1,5-Naphthyridine
Title | Journal |
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1,8-Naphthyridine-2,7-diamine: a potential universal reader of Watson-Crick base pairs for DNA sequencing by electron tunneling. | Organic & biomolecular chemistry 20121121 |
Exploring the role of water molecules for docking and receptor guided 3D-QSAR analysis of naphthyridine derivatives as spleen tyrosine kinase (Syk) inhibitors. | Journal of chemical information and modeling 20121022 |
4-Diphenyl-phosphanyl-1,5-naphthyridine. | Acta crystallographica. Section E, Structure reports online 20121001 |
Novel multifunctional organic semiconductor materials based on 4,8-substituted 1,5-naphthyridine: synthesis, single crystal structures, opto-electrical properties and quantum chemistry calculation. | Organic & biomolecular chemistry 20120907 |
New domino heteroannulation of enaminones: synthesis of diverse fused naphthyridines. | Organic & biomolecular chemistry 20120728 |
A new 4-phenyl-1,8-naphthyridine derivative affects carcinoma cell proliferation by impairing cell cycle progression and inducing apoptosis. | Anti-cancer agents in medicinal chemistry 20120701 |
Synthesis of 1,8-naphthyridines and their application in the development of anionic fluorogenic chemosensors. | Journal of fluorescence 20120701 |
Highly selective binding of naphthyridine with a trifluoromethyl group to cytosine opposite an abasic site in DNA duplexes. | Organic & biomolecular chemistry 20120528 |
In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin. | Toxicology mechanisms and methods 20120401 |
Methyl 1-ethyl-7-methyl-4-oxo-1,4-di-hydro-1,8-naphthyridine-3-carboxyl-ate monohydrate. | Acta crystallographica. Section E, Structure reports online 20120301 |
Enhancement of affinity in molecular recognition via hydrogen bonds by POSS-core dendrimer and its application for selective complex formation between guanosine triphosphate and 1,8-naphthyridine derivatives. | Organic & biomolecular chemistry 20120107 |
Bis(morpholin-4-ium) tetra-chlorido-cobalt(II). | Acta crystallographica. Section E, Structure reports online 20120101 |
Plasmid-Mediated Quinolone Resistance; Interactions between Human, Animal, and Environmental Ecologies. | Frontiers in microbiology 20120101 |
Radiosensitization by the novel DNA intercalating agent vosaroxin. | Radiation oncology (London, England) 20120101 |
A fluorescence study of new angular polycyclic blue light-emitting pyrazolo[3,4-h][1,6]naphthyridine and their interaction with bovine serum albumin (BSA). | Journal of fluorescence 20111101 |
(rac)-1,1'-binaphthyl-based simple receptors designed for fluorometric discrimination of maleic and fumaric acids. | The journal of physical chemistry. B 20110707 |
Aqua-[2-(2-pyrid-yl)-1,8-naphthyridine-κN,N](2,2':6',2''-terpyridine-κN,N',N'')ruthenium(II) bis-(hexa-fluorido-phosphate) acetone sesquisolvate. | Acta crystallographica. Section E, Structure reports online 20110601 |
Diaryl urea analogues of SB-334867 as orexin-1 receptor antagonists. | Bioorganic & medicinal chemistry letters 20110515 |
Triptycene-derived oxacalixarenes as new wheels for the synthesis of [2]rotaxanes: acid-base- and metal-ion-switchable complexation processes. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110502 |
Molecular recognition of the antiretroviral drug abacavir: towards the development of a novel carbazole-based fluorosensor. | Journal of fluorescence 20110501 |
2,6-Diamino-pyridinium tetra-phenyl-borate-1,2-bis-(5,7-dimethyl-1,8-naphthyridin-2-yl)diazene (1/1). | Acta crystallographica. Section E, Structure reports online 20110501 |
7-(4-Meth-oxy-phen-yl)-4,9-dimethyl-N-(4-methyl-phen-yl)-5,12-diaza-tetra-phen-6-amine. | Acta crystallographica. Section E, Structure reports online 20110401 |
Sensitive and selective fluorescence detection of guanosine nucleotides by nanoparticles conjugated with a naphthyridine receptor. | Analytical and bioanalytical chemistry 20110101 |
2,9-Dimethyl-7-phenyl-N-(4-methyl-phen-yl)dibenzo[b,h][1,6]naphthyridin-6-amine. | Acta crystallographica. Section E, Structure reports online 20110101 |
Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. | PloS one 20110101 |
In the quest of drugs for bad bugs: are newer fluoroquinolones any better? | Journal of laboratory physicians 20110101 |
Clinical Use of Inhibitors of HIV-1 Integration: Problems and Prospects. | Acta naturae 20110101 |
Bimetallic catalysis involving dipalladium(I) and diruthenium(I) complexes. | Chemistry (Weinheim an der Bergstrasse, Germany) 20101227 |
Bioactivation of isothiazoles: minimizing the risk of potential toxicity in drug discovery. | Chemical research in toxicology 20101115 |
Novel CGRP receptor antagonists from central amide replacements causing a reversal of preferred chirality. | Bioorganic & medicinal chemistry letters 20101115 |
Voreloxin, a first-in-class anticancer quinolone derivative, acts synergistically with cytarabine in vitro and induces bone marrow aplasia in vivo. | Cancer chemotherapy and pharmacology 20101001 |
Regioselective facile one-pot Friedländer synthesis of sugar-based heterocyclic biomolecules. | Carbohydrate research 20100923 |
Identification of orally available naphthyridine protein kinase D inhibitors. | Journal of medicinal chemistry 20100812 |
QSAR study of substituted 1,3,4-oxadiazole naphthyridines as HIV-1 integrase inhibitors. | European journal of medicinal chemistry 20100701 |
1,3-Diphenyl-3,4-dihydro-benzo[b][1,6]naphthyridine. | Acta crystallographica. Section E, Structure reports online 20100501 |
Molecular recognition studies on naphthyridine derivatives. | Molecules (Basel, Switzerland) 20100303 |
Mapping the transformation [{Ru(II)(CO)(3)Cl(2)}(2)]-->[Ru(I) (2)(CO)(4)](2+): implications in binuclear water-gas shift chemistry. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100222 |
Theoretical study of the peripheral disulfide bridge substituent effects on the antioxidant properties of naphthyridine diol derivatives. | The journal of physical chemistry. A 20100121 |
trans-Pyridyl and naphthyridyl cinnamides as alternatives for urea in complexation of carboxylic acid and formation of water-templated assemblies in the solid state. | The journal of physical chemistry. B 20100114 |
Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II. | PloS one 20100101 |
Suppression of transforming growth factor-β effects in rabbit subconjunctival fibroblasts by activin receptor-like kinase 5 inhibitor. | Molecular vision 20100101 |
Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapy. | Infection and drug resistance 20100101 |
Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses. | Aging cell 20091201 |
N'-[(E)-Benzyl-idene]-1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide. | Acta crystallographica. Section E, Structure reports online 20091201 |
Face-to-face porphyrin moieties assembled with spacing for pyrazine recognition in molecularly imprinted polymers. | Biosensors & bioelectronics 20091115 |
Synergism between pyronaridine and retinol in Plasmodium falciparum in vitro. | Wiener klinische Wochenschrift 20091001 |
Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification. | Journal of medicinal chemistry 20090924 |
Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells. | The Journal of pharmacy and pharmacology 20090801 |
1,5-Naphthyridine as a new linker for the construction of bridging ligands and their corresponding Ru(II) complexes. | Inorganic chemistry 20090720 |
Nitroimidazole-based bioreductive compounds bearing a quinazoline or a naphthyridine chromophore. | Anti-cancer drugs 20090701 |
2,2',4,4'-Tetra-methyl-7,7'-diazenediylbis(1,8-naphthyridin-1-ium) bis-(perchlorate). | Acta crystallographica. Section E, Structure reports online 20090701 |
μ-Bis(5,7-dimethyl-1,8-naphthyridin-2-yl)diazene]bis-[difluoridoboron(III). | Acta crystallographica. Section E, Structure reports online 20090701 |
Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models. | Cancer chemotherapy and pharmacology 20090601 |
3,6-Dimethyl-1-phenyl-4-(2-thien-yl)-8-(2-thienylmethyl-ene)-5,6,7,8-tetra-hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine. | Acta crystallographica. Section E, Structure reports online 20090501 |
N-[6-(Dibromo-meth-yl)-2-pyrid-yl]-2,2-dimethyl-propionamide. | Acta crystallographica. Section E, Structure reports online 20090401 |
1-Ethyl-N'-[(E)-4-hydroxy-benzyl-idene]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide. | Acta crystallographica. Section E, Structure reports online 20090401 |
7-(2,2-Dimethylpropanamido)-2-methyl-1,8-naphthyridin-1-ium chloride monohydrate. | Acta crystallographica. Section E, Structure reports online 20090201 |
Selective targeting of tumorigenic cancer cell lines by microtubule inhibitors. | PloS one 20090101 |
Synthesis, characterization, antibacterial and anti-inflammatory activities of enoxacin metal complexes. | Bioinorganic chemistry and applications 20090101 |
3,5-Dichloro-6-methyl-pyridin-2-amine. | Acta crystallographica. Section E, Structure reports online 20090101 |
Interactions of 1,5-naphthyridine with Pd(en)Cl2 or [Pd(en)(H2O)2](NO3)2 in aqueous solution. | Dalton transactions (Cambridge, England : 2003) 20081207 |
Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase. | Bioorganic & medicinal chemistry letters 20081001 |
Zabofloxacin (DW-224a) activity against Neisseria gonorrhoeae including quinolone-resistant strains. | Diagnostic microbiology and infectious disease 20080901 |
Hexa-μ(2)-acetato-1:2κO:O';1:2κO:O;2:3κO:O';2:3κO:O-bis-(2-amino-7-chloro-5-methyl-1,8-naphthyridine)-1κN,3κN-trizinc(II). | Acta crystallographica. Section E, Structure reports online 20080901 |
2,2'-Dimethyl-7,7'-(methyl-enediimino)di-1,8-naphthyridin-1-ium bis-(perchlorate). | Acta crystallographica. Section E, Structure reports online 20080901 |
Extended metal-atom chains with an inert second row transition metal: [Ru5(mu5-tpda)4X2] (tpda2- = tripyridyldiamido dianion, X = Cl and NCS). | Journal of the American Chemical Society 20080806 |
Toward prediction of alkane/water partition coefficients. | Journal of medicinal chemistry 20080710 |
Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model. | Bioorganic & medicinal chemistry letters 20080601 |
SNS-595, a naphthyridine cell cycle inhibitor and stimulator of apoptosis for the treatment of cancers. | Current opinion in investigational drugs (London, England : 2000) 20080601 |
Raltegravir: first in class HIV integrase inhibitor. | Therapeutics and clinical risk management 20080401 |
cis,trans-Dicarbonyl-dichlorido[2-(2-pyrid-yl)-1,8-naphthyridine-κN,N]ruthenium(II). | Acta crystallographica. Section E, Structure reports online 20080301 |
Fluorescence and electrochemical detection of pyrimidine/purine transversion by a ferrocenyl aminonaphthyridine derivative. | Organic & biomolecular chemistry 20080121 |
Antimalarial therapy selection for quinolone resistance among Escherichia coli in the absence of quinolone exposure, in tropical South America. | PloS one 20080101 |
Raltegravir in the management of HIV-infected patients. | Drug design, development and therapy 20080101 |
Dichloridobis(7-amino-2,4-dimethyl-1,8-naphthyridine-κN,N')cobalt(II) methanol disolvate. | Acta crystallographica. Section E, Structure reports online 20080101 |
Bis(7-amino-2,4-dimethyl-1,8-naphthyridine)dinitratocadmium(II). | Acta crystallographica. Section E, Structure reports online 20080101 |
7-[4-(5,7-Dimethyl-1,8-naphthyridin-2-yl-oxy)phen-oxy]-2,4-dimethyl-1,8-naphthyridine methanol disolvate. | Acta crystallographica. Section E, Structure reports online 20080101 |
Synthesis and SAR comparison of regioisomeric aryl naphthyridines as potent mGlu5 receptor antagonists. | Bioorganic & medicinal chemistry letters 20071201 |
[Study of derivatives of 2, 6-diaminopyridine as fluorescence probe of transition metal ions]. | Guang pu xue yu guang pu fen xi = Guang pu 20071201 |
Synthesis and evaluation of naphthyridine compounds as antimalarial agents. | Bioorganic & medicinal chemistry letters 20071115 |
Rapid and efficient synthesis of 4-substituted pyrazol-5-one under microwave irradiation in solvent-free conditions. | Archiv der Pharmazie 20071101 |
Species-specific, P450- and sulfotransferase-mediated novel ring contraction of a naphthyridine-N-oxide compound in cynomolgus monkey. | Chemical research in toxicology 20071101 |
Synthesis and structure-activity relationships of potent antitumor active quinoline and naphthyridine derivatives. | Anti-cancer agents in medicinal chemistry 20071101 |
Tetrahydro-1,8-naphthyridinol analogues of alpha-tocopherol as antioxidants in lipid membranes and low-density lipoproteins. | Journal of the American Chemical Society 20070822 |
Analysis of mismatched DNA by mismatch binding ligand (MBL)-Sepharose affinity chromatography. | Analytical and bioanalytical chemistry 20070701 |
Tosufloxacin tosilate-induced thrombocytopenic purpura. | The Journal of dermatology 20070701 |
Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites. | Biochemistry 20070508 |
Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors. | Bioorganic & medicinal chemistry letters 20070501 |
2-Amino-5,7-dimethyl-1,8-naphthyridine as a fluorescent reagent for the determination of nitrite. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070301 |
In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate. | Retrovirology 20070101 |
Multi-class confirmatory method for analyzing trace levels of tetracyline and quinolone antibiotics in pig tissues by ultra-performance liquid chromatography coupled with tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20070101 |
Electrochemical and fluorescence detection of cytosine-related SNPs using a ferrocenyl naphthyridine derivative. | Nucleic acids symposium series (2004) 20070101 |
Fluorescence-based affinity labeling of nucleobase by hydrogen-bond forming metal complex. | Nucleic acids symposium series (2004) 20070101 |
Strong binding of naphthyridine derivatives to cytosine in an AP site-containing DNA duplex and their application to fluorescence detection of single nucleotide polymorphisms. | Nucleic acids symposium series (2004) 20070101 |
First total synthesis of the 2,7-naphthyridine alkaloids lophocladine a and B. | Archiv der Pharmazie 20061201 |
Ratiometric fluorescence detection of pyrimidine/purine transversion by using a 2-amino-1,8-naphthyridine derivative. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060201 |
Effects of anti-inflammatory [1, 2, 4]triazolo[4, 3-a] [1, 8]naphthyridine derivatives on human stimulated PMN and endothelial cells: an in vitro study. | Journal of inflammation (London, England) 20060101 |
A quadruply hydrogen bonded heterocomplex displaying high-fidelity recognition. | Journal of the American Chemical Society 20051228 |
Luminescence ranging from red to blue: a series of copper(I)-halide complexes having rhombic {Cu2(mu-X)2} (X = Br and I) units with N-heteroaromatic ligands. | Inorganic chemistry 20051226 |
Hydrogen bond directed synthesis of pyridazine and naphthyridine containing macrocycles. | Chemical communications (Cambridge, England) 20051214 |
Two-stage sensing property via a conjugated donor-acceptor-donor constitution: application to the visual detection of mercuric ion. | The Journal of organic chemistry 20050722 |
A highly stable quadruply hydrogen-bonded heterocomplex useful for supramolecular polymer blends. | Journal of the American Chemical Society 20050511 |
The effect of reduction on rhenium(I) complexes with binaphthyridine and biquinoline ligands: a spectroscopic and computational study. | The journal of physical chemistry. A 20050428 |
NMR structural analysis of the G.G mismatch DNA complexed with naphthyridine-dimer. | Nucleic acids symposium series (2004) 20050101 |
Strong binding of naphthyridine derivatives to a guanine base in DNA duplexes containing an AP site. | Nucleic acids symposium series (2004) 20050101 |
Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. | Journal of medicinal chemistry 20040826 |
Formation of branched calixarene aggregates-a time-resolved static light scattering study. | Journal of the American Chemical Society 20040804 |
The binding of guanine-guanine mismatched DNA to naphthyridine dimer immobilized sensor surfaces: kinetic aspects. | Bioorganic & medicinal chemistry 20040615 |
Synthesis and biological evaluation of 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives as new ligands of cannabinoid receptors. | Bioorganic & medicinal chemistry 20040415 |
Enoxacin trihydrate. | Acta crystallographica. Section C, Crystal structure communications 20040401 |
Antineoplastic agents. 499. Synthesis of hystatin 2 and related 1H-benzo[de][1,6]-naphthyridinium salts from aaptamine. | Journal of medicinal chemistry 20040325 |
Highly sensitive detection of GG mismatched DNA by surfaces immobilized naphthyridine dimer through poly(ethylene oxide) linkers. | Bioorganic & medicinal chemistry letters 20040308 |
Affinity labeling of a single guanine bulge. | Journal of the American Chemical Society 20030730 |
Spectroscopic and theoretical studies of derivatives of 1,6- and 1,7-naphthyridines. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030501 |
Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors. | Journal of medicinal chemistry 20030327 |
Formation and destruction of the guanine quartet in solution observed by cold-spray ionization mass spectrometry. | Chemical communications (Cambridge, England) 20030321 |
Induction of a remarkable conformational change in a human telomeric sequence by the binding of naphthyridine dimer: inhibition of the elongation of a telomeric repeat by telomerase. | Journal of the American Chemical Society 20030122 |
The binding of naphthyridine tetramer to guanine-rich sequences. | Nucleic acids research. Supplement (2001) 20030101 |
Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1. | Journal of medicinal chemistry 20021205 |
Chemically induced hairpin formation in DNA monolayers. | Journal of the American Chemical Society 20020619 |
Binding analysis between naphthyridine dimers and GG mismatch DNA. | Nucleic acids research. Supplement (2001) 20020101 |
Recognition of guanine-guanine mismatches by the dimeric form of 2-amino-1,8-naphthyridine. | Journal of the American Chemical Society 20011219 |
Improved selectivity for the binding of naphthyridine dimer to guanine-guanine mismatch. | Bioorganic & medicinal chemistry 20010901 |
5-amino-4-(4-diethylaminophenyl)-2-(4-hydroxyphenyl)-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbonitrile. | Acta crystallographica. Section C, Crystal structure communications 20010601 |
Selective amination of secoiridoid glycosides to give monomeric pyridine, dimeric pyridine, and naphthyridine alkaloids. | Natural product letters 20010101 |