(S)-3-(Piperidin-2-yl)pyridine
Title | Journal |
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Piperidine, pyridine alkaloid inhibition of fetal movement in a day 40 pregnant goat model. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130801 |
Effect of α₇ nicotinic acetylcholine receptor agonists and antagonists on motor function in mice. | Toxicology and applied pharmacology 20130201 |
Derivatization of chiral carboxylic acids with (S)-anabasine for increasing detectability and enantiomeric separation in LC/ESI-MS/MS. | Journal of separation science 20121101 |
Synthesis and biological activity evaluation of novel β-substituted nitromethylene neonicotinoid analogues. | Molecules (Basel, Switzerland) 20120824 |
Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptor. | The Journal of biological chemistry 20120622 |
N'-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: design, synthesis, crystal structure, insecticidal activity, and structure-activity relationships. | Journal of agricultural and food chemistry 20120523 |
Insecticide residues in pollen and nectar of a cucurbit crop and their potential exposure to pollinators. | Journal of agricultural and food chemistry 20120509 |
Assessment of the environmental exposure of honeybees to particulate matter containing neonicotinoid insecticides coming from corn coated seeds. | Environmental science & technology 20120306 |
Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs. | Bioorganic & medicinal chemistry letters 20120115 |
[Reversible lupininin inhibitors of cholinesterases of mammalian blood and of optical ganglia of individuals of the commander squid Berryteuthis magister from different zones of species areal]. | Zhurnal evoliutsionnoi biokhimii i fiziologii 20120101 |
LC-MS/MS analysis of neonicotinoid insecticides in honey: methodology and residue findings in Austrian honeys. | Journal of agricultural and food chemistry 20111214 |
A one-year monitoring of nicotine use in sport: frontier between potential performance enhancement and addiction issues. | Forensic science international 20111210 |
Simultaneous quantification of nicotine and metabolites in rat brain by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115 |
Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. | European journal of medicinal chemistry 20111101 |
Design, synthesis, crystal structure analysis, and insecticidal evaluation of phenylazoneonicotinoids. | Journal of agricultural and food chemistry 20111012 |
Short-term intubation after ingestion of Nicotiana glauca. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110915 |
[Detection of chloropyridinyl neonicotinoid insecticide metabolite 6-chloronicotinic acid in the urine: six cases with subacute nicotinic symptoms]. | Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20110901 |
The biology of insecticidal activity and resistance. | Insect biochemistry and molecular biology 20110701 |
N-haloacetylimino neonicotinoids: potency and molecular recognition at the insect nicotinic receptor. | Bioorganic & medicinal chemistry letters 20110615 |
Quantitative determination of bisphenol A from human saliva using bulk derivatization and trap-and-elute liquid chromatography coupled to electrospray ionization mass spectrometry. | Environmental toxicology and chemistry 20110601 |
Overview of the status and global strategy for neonicotinoids. | Journal of agricultural and food chemistry 20110413 |
Neonicotinoid metabolism: compounds, substituents, pathways, enzymes, organisms, and relevance. | Journal of agricultural and food chemistry 20110413 |
Receptor structure-guided neonicotinoid design. | Journal of agricultural and food chemistry 20110413 |
Importance of physicochemical properties for the design of new pesticides. | Journal of agricultural and food chemistry 20110413 |
cis-Configuration: a new tactic/rationale for neonicotinoid molecular design. | Journal of agricultural and food chemistry 20110413 |
Neonicotinoid insecticides: highlights of a symposium on strategic molecular designs. | Journal of agricultural and food chemistry 20110413 |
Unique neonicotinoid binding conformations conferring selective receptor interactions. | Journal of agricultural and food chemistry 20110413 |
Tying it all together--papers from two noteworthy symposia dealing with recent developments in agrochemical research. | Journal of agricultural and food chemistry 20110413 |
Nicotiana glauca (tree tobacco) intoxication--two cases in one family. | Journal of medical toxicology : official journal of the American College of Medical Toxicology 20110301 |
New fears over bee declines. | Current biology : CB 20110222 |
Application of catalytic dynamic resolution of N-Boc-2-lithiopiperidine to the asymmetric synthesis of 2-aryl and 2-vinyl piperidines. | Organic letters 20110204 |
Nicotine and metabolites in paired umbilical cord tissue and meconium specimens. | Therapeutic drug monitoring 20110201 |
[An experimental study on chemically induced animal model of goat cleft palate in uterus]. | Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20110201 |
Effects of binary mixtures on the life traits of Daphnia magna. | Ecotoxicology and environmental safety 20110101 |
Determination of neonicotinoid insecticides residues in bovine tissues by pressurized solvent extraction and liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110101 |
Advanced research on cis-Neonicotinoids. | Chimia 20110101 |
Determination of nicotine, anabasine, and cotinine in urine and saliva samples using single-drop microextraction. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015 |
The significance of the Druckrey-Küpfmüller equation for risk assessment--the toxicity of neonicotinoid insecticides to arthropods is reinforced by exposure time. | Toxicology 20100930 |
The conformational landscape of nicotinoids: solving the conformational disparity of anabasine. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100903 |
Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identification. | Journal of medicinal chemistry 20100624 |
Multiresidue analysis of neonicotinoids by solid-phase extraction technique using high-performance liquid chromatography. | Environmental monitoring and assessment 20100601 |
A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein. | European journal of medicinal chemistry 20100601 |
Discovery of bis-aromatic ring neonicotinoid analogues fixed as cis-configuration: Synthesis, insecticidal activities, and molecular docking studies. | Bioorganic & medicinal chemistry letters 20100601 |
Refined methodology for the determination of neonicotinoid pesticides and their metabolites in honey bees and bee products by liquid chromatography-tandem mass spectrometry (LC-MS/MS). | Journal of agricultural and food chemistry 20100526 |
Trifluoroacetyl neonicotinoid insecticides with enhanced hydrophobicity and effectiveness. | Journal of agricultural and food chemistry 20100428 |
Risk assessment for side-effects of neonicotinoids against bumblebees with and without impairing foraging behavior. | Ecotoxicology (London, England) 20100101 |
Quantitation of nicotine, its metabolites, and other related alkaloids in urine, serum, and plasma using LC-MS-MS. | Methods in molecular biology (Clifton, N.J.) 20100101 |
The addition of five minor tobacco alkaloids increases nicotine-induced hyperactivity, sensitization and intravenous self-administration in rats. | The international journal of neuropsychopharmacology 20091101 |
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor. | The EMBO journal 20091007 |
Synthesis of a neonicotinoide pesticide derivative via chemoenzymatic dynamic kinetic resolution. | The Journal of organic chemistry 20091002 |
Diverse actions and target-site selectivity of neonicotinoids: structural insights. | Molecular pharmacology 20090701 |
Differential regulation of receptor activation and agonist selectivity by highly conserved tryptophans in the nicotinic acetylcholine receptor binding site. | The Journal of pharmacology and experimental therapeutics 20090701 |
Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine. | The Journal of pharmacology and experimental therapeutics 20090501 |
Interaction of benzylidene-anabaseine analogues with agonist and allosteric sites on muscle nicotinic acetylcholine receptors. | British journal of pharmacology 20090501 |
Influence of posttreatment temperature on the toxicity of insecticides against Diaphorina citri (Hemiptera: Psyllidae). | Journal of economic entomology 20090401 |
Neonicotinoid substituents forming a water bridge at the nicotinic acetylcholine receptor. | Journal of agricultural and food chemistry 20090325 |
Positive modulation of alpha7 nAChR responses in rat hippocampal interneurons to full agonists and the alpha7-selective partial agonists, 4OH-GTS-21 and S 24795. | Neuropharmacology 20090301 |
Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system. | Journal of agricultural and food chemistry 20090211 |
Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation? | Biochimica et biophysica acta 20090201 |
Determination of nicotine, cotinine, and related alkaloids in human urine and saliva by automated in-tube solid-phase microextraction coupled with liquid chromatography-mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20090115 |
Synthesis, crystal structure, insecticidal activity and DFT study on the geometry and vibration of O-(E)-1-{1-[(6-chloropyridin-3-yl)methyl]-5-methyl-1H-1,2,3-triazol-4-yl}ethyleneamino-O-ethyl-O-phenylphosphorothioate. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201 |
Susceptibility to neonicotinoids and risk of resistance development in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). | Pest management science 20081201 |
Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated alpha7 nicotinic receptor gene transfer. | Brain research 20080408 |
Enantiomeric analysis of anatabine, nornicotine and anabasine in commercial tobacco by multi-dimensional gas chromatography and mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080401 |
Sequential preconcentration by coupling of field amplified sample injection with pseudo isotachophoresis-acid stacking for analysis of alkaloids in capillary electrophoresis. | Analytical and bioanalytical chemistry 20080301 |
Palladium-catalyzed direct C-h arylation of N-iminopyridinium ylides: application to the synthesis of (+/-)-anabasine. | Journal of the American Chemical Society 20080109 |
Effect of anabasine on catecholamine secretion from the perfused rat adrenal medulla. | Journal of cardiology 20071201 |
The effect of the cholinergic anti-inflammatory pathway on experimental colitis. | Scandinavian journal of immunology 20071101 |
Blocking actions of alkylene-tethered bis-neonicotinoids on nicotinic acetylcholine receptors expressed by terminal abdominal ganglion neurons of Periplaneta americana. | Neuroscience letters 20071002 |
Analyses of tobacco alkaloids by cation-selective exhaustive injection sweeping microemulsion electrokinetic chromatography. | Journal of chromatography. A 20070914 |
The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice. | Neuroscience 20070810 |
Effects of tobacco and cigarette smoke extracts on serotonergic raphe neurons in the rat. | Neuroreport 20070611 |
Simultaneous determination of neonicotinoid insecticides in agricultural samples by solid-phase extraction cleanup and liquid chromatography equipped with diode-array detection. | Journal of agricultural and food chemistry 20070516 |
Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification. | Journal of agricultural and food chemistry 20070321 |
A hypothesis to account for the selective and diverse actions of neonicotinoid insecticides at their molecular targets, nicotinic acetylcholine receptors: catch and release in hydrogen bond networks. | Invertebrate neuroscience : IN 20070301 |
Reversal of agonist selectivity by mutations of conserved amino acids in the binding site of nicotinic acetylcholine receptors. | The Journal of biological chemistry 20070223 |
Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore. | Journal of agricultural and food chemistry 20070207 |
Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein. | The Journal of biological chemistry 20061222 |
Complete assignments 1H and 13C NMR spectral data of four anabaseine derivatives. | Magnetic resonance in chemistry : MRC 20061201 |
Specific detection of anabasine, nicotine, and nicotine metabolites in urine by liquid chromatography-tandem mass spectrometry. | American journal of clinical pathology 20061201 |
A nicotinic acetylcholine receptor mutation (Y151S) causes reduced agonist potency to a range of neonicotinoid insecticides. | Journal of neurochemistry 20061101 |
Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site. | Molecular pharmacology 20061001 |
Anabasine toxicity from a topical folk remedy. | Clinical pediatrics 20060901 |
Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions. | Biochemistry 20060725 |
Chloropyridinyl neonicotinoid insecticides: diverse molecular substituents contribute to facile metabolism in mice. | Chemical research in toxicology 20060701 |
N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine. | The Journal of pharmacology and experimental therapeutics 20060601 |
Resistance and cross-resistance to neonicotinoid insecticides and spinosad in the Colorado potato beetle, Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae). | Pest management science 20060101 |
Assignment of absolute configuration of cyclic secondary amines by NMR techniques using Mosher's method: a general procedure exemplified with (-)-isoanabasine. | Magnetic resonance in chemistry : MRC 20060101 |
Substrate specificity of rabbit aldehyde oxidase for nitroguanidine and nitromethylene neonicotinoid insecticides. | Chemical research in toxicology 20060101 |
Relative toxicities and neuromuscular nicotinic receptor agonistic potencies of anabasine enantiomers and anabaseine. | Neurotoxicology and teratology 20060101 |
[Analogs of anabasine as reversible and irreversible inhibitors of choline esterases of different animals]. | Zhurnal evoliutsionnoi biokhimii i fiziologii 20060101 |
Analysis of pesticides in fruits by pressurized liquid extraction and liquid chromatography-ion trap-triple stage mass spectrometry. | Journal of chromatography. A 20051209 |
Rhesus monkey alpha7 nicotinic acetylcholine receptors: comparisons to human alpha7 receptors expressed in Xenopus oocytes. | European journal of pharmacology 20051107 |
A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine. | The AAPS journal 20050901 |
Neonicotinoids show selective and diverse actions on their nicotinic receptor targets: electrophysiology, molecular biology, and receptor modeling studies. | Bioscience, biotechnology, and biochemistry 20050801 |
Stereoselectivity of the demethylation of nicotine piperidine homologues by Nicotiana plumbaginifolia cell suspension cultures. | Phytochemistry 20050801 |
Identification of aldehyde oxidase as the neonicotinoid nitroreductase. | Chemical research in toxicology 20050201 |
Inhibition of cholinesterases of various origin by anabasine derivatives. | Doklady. Biochemistry and biophysics 20050101 |
Role of neonicotinyl insecticides in Washington apple integrated pest management. Part II. Nontarget effects on integrated mite control. | Journal of insect science (Online) 20050101 |
Coaxing a pyridine nucleus to give up its aromaticity: synthesis and pharmacological characterization of novel conformationally restricted analogues of nicotine and anabasine. | Journal of medicinal chemistry 20041230 |
On-line screening of conformationally constrained nicotines and anabasines for agonist activity at the alpha3beta4- and alpha4beta2-nicotinic acetylcholine receptors using immobilized receptor-based liquid chromatographic stationary phases. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225 |
Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry. | Clinical chemistry 20041201 |
Quantitative structure-activity relationship study using refractotopological state atom index on some neonicotinoid insecticides. | Bioorganic & medicinal chemistry 20041201 |
Comparative analysis of neonicotinoid binding to insect membranes: I. A structure-activity study of the mode of [3H]imidacloprid displacement in Myzus persicae and Aphis craccivora. | Pest management science 20041001 |
Comparative analysis of neonicotinoid binding to insect membranes: II. An unusual high affinity site for [3H]thiamethoxam in Myzus persicae and Aphis craccivora. | Pest management science 20041001 |
Anabasine, a selective nicotinic acetylcholine receptor agonist, antagonizes MK-801-elicited mouse popping behavior, an animal model of schizophrenia. | Behavioural brain research 20040831 |
The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors. | Molecular pharmacology 20040701 |
Structural diversity and defensive properties of norditerpenoid alkaloids. | Journal of chemical ecology 20040701 |
Super agonist actions of clothianidin and related compounds on the SAD beta 2 nicotinic acetylcholine receptor expressed in Xenopus laevis oocytes. | Bioscience, biotechnology, and biochemistry 20040301 |
Inhibitory effect of cadmium and tobacco alkaloids on expansion of porcine oocyte-cumulus complexes. | Central European journal of public health 20040301 |
Ligation of CD47 during monocyte differentiation into dendritic cells results in reduced capacity for interleukin-12 production. | Scandinavian journal of immunology 20040101 |
[Application of bisalkaloid derivatives of dicarboxylic acids based on lupinine, anabasine and cytisine as cholinesterase inhibitors of various origin]. | Zhurnal evoliutsionnoi biokhimii i fiziologii 20040101 |
Novaluron (Rimon), a novel IGR: potency and cross-resistance. | Archives of insect biochemistry and physiology 20031201 |
Inhibition of barnacle larval settlement and crustacean toxicity of some hoplonemertine pyridyl alkaloids. | Biomolecular engineering 20030701 |
Studies on intramolecular Diels-Alder reactions of furo[3,4-c]pyridines in the synthesis of conformationally restricted analogues of nicotine and anabasine. | The Journal of organic chemistry 20030530 |
Dihydropiperazine neonicotinoid compounds. Synthesis and insecticidal activity. | Journal of agricultural and food chemistry 20030507 |
Regulation of neuronal function by choline and 4OH-GTS-21 through alpha 7 nicotinic receptors. | Journal of neurophysiology 20030401 |
Variation in response to neonicotinoid insecticides in peach-potato aphids, Myzus persicae (Hemiptera: Aphididae). | Pest management science 20030201 |
Bisalkaloid derivatives of dicarboxylic acids on the basis of lupinine, anabasine, and cytisine as reversible cholinesterase inhibitors. | Doklady. Biochemistry and biophysics 20030101 |
Components of cigarette smoke inhibit expansion of oocyte-cumulus complexes from porcine follicles. | Physiological research 20030101 |
[Sensitive nonradioactive screening method for compounds interacting with alpha7-cholinoreceptor]. | Bioorganicheskaia khimiia 20030101 |
Quantitative structure-activity relationship study on some azidopyridinyl neonicotinoid insecticides for their selective affinity towards the drosophila nicotinic receptor over mammalian alpha4beta2 receptor using electrotopological state atom index. | Drug design and discovery 20030101 |
Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021201 |
Activation and inhibition of native neuronal alpha-bungarotoxin-sensitive nicotinic ACh receptors. | Brain research 20020906 |
Structure-activity relationships of benzylidene anabaseines in nicotinic acetylcholine receptors of cockroach nerve cords. | Bioorganic & medicinal chemistry 20020901 |
Comparative pharmacology of rat and human alpha7 nAChR conducted with net charge analysis. | British journal of pharmacology 20020901 |
Simultaneous analysis of nicotine, nicotine metabolites, and tobacco alkaloids in serum or urine by tandem mass spectrometry, with clinically relevant metabolic profiles. | Clinical chemistry 20020901 |
Accidental fatal poisoning by Nicotiana glauca: identification of anabasine by high performance liquid chromatography/photodiode array/mass spectrometry. | Forensic science international 20020717 |
Enantioselective synthesis of 2-arylpiperidines from chiral lactams. A concise synthesis of (-)-anabasine. | Chemical communications (Cambridge, England) 20020307 |
Translocation and translaminar bioavailability of two neonicotinoid insecticides after foliar application to cabbage and cotton. | Pest management science 20020101 |
Benzylidene analogs of anabaseine display partial agonist and antagonist properties at the mouse 5-hydroxytryptamine(3A) receptor. | The Journal of pharmacology and experimental therapeutics 20011201 |
Insecticidal and neural activities of candidate photoaffinity probes for neonicotinoid binding sites. | Bioscience, biotechnology, and biochemistry 20010701 |
Absolute configuration of anabasine from Messor and Aphaenogaster ants. | Journal of chemical ecology 20010501 |
The discovery of thiamethoxam: a second-generation neonicotinoid. | Pest management science 20010201 |
GTS-21, a mixed nicotinic receptor agonist/antagonist, does not affect the nicotine cue. | Pharmacology, biochemistry, and behavior 19991001 |