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PLoS neglected tropical diseases 20120501

Non-histone lysine acetylated proteins in heart failure.

Biochimica et biophysica acta 20120401

Is histone acetylation the most important physiological function for CBP and p300?

Aging 20120401

Histone recognition and large-scale structural analysis of the human bromodomain family.

Cell 20120330

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FEBS letters 20120323

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Molecular biology reports 20120301

Trapping of cis-2-butene-1,4-dial to measure furan metabolism in human liver microsomes by cytochrome P450 enzymes.

Drug metabolism and disposition: the biological fate of chemicals 20120301

SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120201

Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides.

Journal of medicinal chemistry 20120126

SIRT1 contains N- and C-terminal regions that potentiate deacetylase activity.

The Journal of biological chemistry 20120120

Dual modification of Alzheimer's disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach.

Acta neuropathologica 20120101

Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function.

PloS one 20120101

Increasing dietary fat elicits similar changes in fat oxidation and markers of muscle oxidative capacity in lean and obese humans.

PloS one 20120101

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Frontiers in pharmacology 20120101

Structures, substrates, and regulators of Mammalian sirtuins - opportunities and challenges for drug development.

Frontiers in pharmacology 20120101

Transcriptional repressor NIR functions in the ribosome RNA processing of both 40S and 60S subunits.

PloS one 20120101

Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.

Molecular systems biology 20120101

Arsenic trioxide exerts antimyeloma effects by inhibiting activity in the cytoplasmic substrates of histone deacetylase 6.

PloS one 20120101

Function of the active site lysine autoacetylation in Tip60 catalysis.

PloS one 20120101

Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions.

PloS one 20120101

Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation.

PloS one 20120101

Identifying acetylated proteins in mitosis.

Methods in molecular biology (Clifton, N.J.) 20120101

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Current opinion in structural biology 20111201

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Druggability of methyl-lysine binding sites.

Journal of computer-aided molecular design 20111201

Metabolic variation during development in culture of Leishmania donovani promastigotes.

PLoS neglected tropical diseases 20111201

The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis.

Nature cell biology 20111120

Aspirin acetylates multiple cellular proteins in HCT-116 colon cancer cells: Identification of novel targets.

International journal of oncology 20111101

Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns.

Molecular & cellular proteomics : MCP 20111101

Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.

PLoS biology 20111101

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands.

Journal of medicinal chemistry 20111013

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.

Nature 20111002

BET bromodomain inhibition as a therapeutic strategy to target c-Myc.

Cell 20110916

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Expert reviews in molecular medicine 20110901

Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway.

The Journal of biological chemistry 20110812

SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.

Aging 20110601

Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.

PLoS genetics 20110601

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.

Nature communications 20110501

Preparation of fully synthetic histone H3 reveals that acetyl-lysine 56 facilitates protein binding within nucleosomes.

Journal of molecular biology 20110429

A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes.

Chemistry & biology 20110422

CLU blocks HDACI-mediated killing of neuroblastoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110401

Resveratrol-mediated SIRT-1 interactions with p300 modulate receptor activator of NF-kappaB ligand (RANKL) activation of NF-kappaB signaling and inhibit osteoclastogenesis in bone-derived cells.

The Journal of biological chemistry 20110401

The path to clinical proteomics research: integration of proteomics, genomics, clinical laboratory and regulatory science.

The Korean journal of laboratory medicine 20110401

Capillary electrophoresis-based sirtuin assay using non-peptide substrates.

Journal of pharmaceutical and biomedical analysis 20110325

hALP, a novel transcriptional U three protein (t-UTP), activates RNA polymerase I transcription by binding and acetylating the upstream binding factor (UBF).

The Journal of biological chemistry 20110304

Enhanced reactivity of Lys182 explains the limited efficacy of biogenic amines in preventing the inactivation of glucose-6-phosphate dehydrogenase by methylglyoxal.

Bioorganic & medicinal chemistry 20110301

H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation.

PLoS genetics 20110301

Rational design of cyclic peptide modulators of the transcriptional coactivator CBP: a new class of p53 inhibitors.

Journal of the American Chemical Society 20110223

SIRT3 substrate specificity determined by peptide arrays and machine learning.

ACS chemical biology 20110218

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Diabetes 20110101

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Protein science : a publication of the Protein Society 20110101

Histone deacetylase inhibitors: the epigenetic therapeutics that repress hypoxia-inducible factors.

Journal of biomedicine & biotechnology 20110101

Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies?

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Histone H4 lysine 12 acetylation regulates telomeric heterochromatin plasticity in Saccharomyces cerevisiae.

PLoS genetics 20110101

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PloS one 20110101

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Nutrition & metabolism 20110101

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PloS one 20110101

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Journal of aging research 20110101

Post-translational protein modification by carotenoid cleavage products.

BioFactors (Oxford, England) 20110101

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Genome biology 20110101

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PloS one 20110101

Metabolomic Characterization of Ovarian Epithelial Carcinomas by HRMAS-NMR Spectroscopy.

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International journal of biological sciences 20110101

The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells.

PloS one 20110101

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PloS one 20110101

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Molecular cancer 20110101

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PloS one 20110101

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Handbook of experimental pharmacology 20110101

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PloS one 20110101

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International journal of molecular sciences 20110101

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Bioinformation 20110101

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Current chemical genomics 20110101

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PloS one 20110101

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Nature 20101223

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Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20101028

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Oncogene 20101021

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Bioinformatics (Oxford, England) 20101015

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Deciphering normal blood gene expression variation--The NOWAC postgenome study.

PLoS genetics 20100301

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BMC genomics 20100101

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European journal of mass spectrometry (Chichester, England) 20100101

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International journal of cell biology 20100101

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BMC molecular biology 20100101

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Nature 20091001

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Current opinion in drug discovery & development 20090901

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Bioorganic & medicinal chemistry letters 20090801

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Chemical research in toxicology 20090701

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Chemical research in toxicology 20090601

A mechanistic investigation into the irreversible protein binding and antigenicity of p-phenylenediamine.

Chemical research in toxicology 20090601

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ACS chemical biology 20090515

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Applied biochemistry and biotechnology 20090501

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Chemical research in toxicology 20090501

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The EMBO journal 20090121

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Toxicological sciences : an official journal of the Society of Toxicology 20090101

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Molecular cancer 20090101

Computational screening of molecular targets in Plasmodium for novel non resistant anti-malarial drugs.

Bioinformation 20090101

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Methods in molecular biology (Clifton, N.J.) 20090101

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Retrovirology 20090101

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Journal of the American Chemical Society 20081210

Establishment of glutamine synthetase of Mycobacterium smegmatis as a protein acetyltransferase utilizing polyphenolic acetates as the acetyl group donors.

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Electrophoresis 20080901

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PLoS genetics 20080301

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Bioscience, biotechnology, and biochemistry 20080201

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BMC cell biology 20080101

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Nuclear receptor signaling 20080101

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BMC developmental biology 20080101

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Angewandte Chemie (International ed. in English) 20080101

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Arthritis research & therapy 20080101

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BMC molecular biology 20080101

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Genome biology 20080101

Tumor microvasculature: endothelial leakiness and endothelial pore size distribution in a breast cancer model.

Breast cancer : basic and clinical research 20080101

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Biochemistry 20071218

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Carbohydrate research 20071210

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Structural basis for nicotinamide inhibition and base exchange in Sir2 enzymes.

Molecular cell 20070209

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Nature chemical biology 20070101

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Molecular cancer 20070101

Characterization of protein transacetylase from human placenta as a signaling molecule calreticulin using polyphenolic peracetates as the acetyl group donors.

Cell biochemistry and biophysics 20070101

Requirement of histone deacetylase activity for the expression of critical photoreceptor genes.

BMC developmental biology 20070101

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BMC structural biology 20070101

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Eukaryotic cell 20061001

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Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases.

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BMC genomics 20060101

Target structure-based discovery of small molecules that block human p53 and CREB binding protein association.

Chemistry & biology 20060101

Hydralazine target: from blood vessels to the epigenome.

Journal of translational medicine 20060101

Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine.

Molecular pain 20060101

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Characterization of a lysK gene as an argE homolog in Thermus thermophilus HB27.

FEBS letters 20020213

Generation of intramolecular and intermolecular sulfenamides, sulfinamides, and sulfonamides by hypochlorous acid: a potential pathway for oxidative cross-linking of low-density lipoprotein by myeloperoxidase.

Biochemistry 20020129

The diversity of acetylated proteins.

Genome biology 20020101

Capillary electrophoretic separation by double-strand polyaniline-coate capillaries of the advanced glycation endproducts formed from N-alpha-acetyl-L-lysine with reducing sugars.

Journal of capillary electrophoresis and microchip technology 20020101

Structure of histone deacetylases: insights into substrate recognition and catalysis.

Structure (London, England : 1993) 20011201

Duality in bromodomain-containing protein complexes.

Frontiers in bioscience : a journal and virtual library 20010801

Acetyllysine-binding and function of bromodomain-containing proteins in chromatin.

Frontiers in bioscience : a journal and virtual library 20010801

The bromodomain: a chromatin browser?

Frontiers in bioscience : a journal and virtual library 20010801

The bromodomain: a regulator of ATP-dependent chromatin remodeling?

Frontiers in bioscience : a journal and virtual library 20010801

Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation.

The Journal of biological chemistry 20010406

Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate.

Free radical biology & medicine 20010301

Early glycation products produce pentosidine cross-links on native proteins. novel mechanism of pentosidine formation and propagation of glycation.

The Journal of biological chemistry 20010209

Enzyme immunoassay for aflatoxin B1-lysine adduct and its validation.

Journal of AOAC International 20010101