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Marfey's reagent

CAS No.:
95713-52-3
Catalog Number:
AG0032GL
Molecular Formula:
C9H9FN4O5
Molecular Weight:
272.1900
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
97%
In Stock USA
United States
$132
- +
5g
97%
In Stock USA
United States
$457
- +
10g
97%
In Stock USA
United States
$775
- +
25g
97%
In Stock USA
United States
$1563
- +
Product Description
Catalog Number:
AG0032GL
Chemical Name:
Marfey's reagent
CAS Number:
95713-52-3
Molecular Formula:
C9H9FN4O5
Molecular Weight:
272.1900
MDL Number:
MFCD00042049
IUPAC Name:
(2S)-2-(5-fluoro-2,4-dinitroanilino)propanamide
InChI:
InChI=1S/C9H9FN4O5/c1-4(9(11)15)12-6-2-5(10)7(13(16)17)3-8(6)14(18)19/h2-4,12H,1H3,(H2,11,15)/t4-/m0/s1
InChI Key:
NEPLBHLFDJOJGP-BYPYZUCNSA-N
SMILES:
NC(=O)[C@@H](Nc1cc(F)c(cc1[N+](=O)[O-])[N+](=O)[O-])C
Properties
Complexity:
382  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
272.056g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
272.192g/mol
Monoisotopic Mass:
272.056g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
147A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.6  
Literature
Title Journal
A universal HPLC-MS method to determine the stereochemistry of common and unusual amino acids. Methods in molecular biology (Clifton, N.J.) 20120101
Use of Marfey's reagent and analogs for chiral amino acid analysis: assessment and applications to natural products and biological systems. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Indirect reversed-phase high-performance liquid chromatographic and direct thin-layer chromatographic enantioresolution of (R,S)-Cinacalcet. Biomedical chromatography : BMC 20110601
Indirect enantioresolution of (R,S)-mexiletine by reversed-phase high-performance liquid chromatography via diastereomerization with [(S,S)-O,O'-di-p-toluoyl tartaric acid anhydride], (S)-naproxen and nine chiral reagents synthesized as variants of Marfey's reagent. Biomedical chromatography : BMC 20110301
Fast chiral separation of drugs using columns packed with sub-2 microm particles and ultra-high pressure. Chirality 20100301
A liquid chromatography-tandem mass spectrometry assay for Marfey's derivatives of L-Ala, D-Ala, and D-Ala-D-Ala: application to the in vivo confirmation of alanine racemase as the target of cycloserine in Escherichia coli. Analytical biochemistry 20100101
Reversed-phase liquid chromatographic determination of enantiomers of atenolol in rat plasma using derivatization with Marfey's reagent. Biomedical chromatography : BMC 20090701
Reversed-phase high performance liquid chromatographic separation of diastereomers of beta-amino alcohols and microwave assisted synthesis of Marfey's reagent, its chiral variants and diastereomers. Journal of chromatography. A 20090320
Chromatographic separation of enantiomers of non-protein alpha-amino acids after derivatization with Marfey's reagent and its four variants. Amino acids 20090301
Indirect resolution of baclofen enantiomers from pharmaceutical dosage form by reversed-phase liquid chromatography after derivatization with Marfey's reagent and its structural variants. Biomedical chromatography : BMC 20080801
Indirect resolution of enantiomers of penicillamine by TLC and HPLC using Marfey's reagent and its variants. Biomedical chromatography : BMC 20071001
Analysis of monoethanolamine by derivatization with Marfey's reagent and HPLC. Journal of chromatographic science 20070301
Quantification of serine enantiomers in rat brain microdialysate using Marfey's reagent and LC/MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201
Stereochemical heterogeneity in Verongid sponge metabolites. Absolute stereochemistry of (+)-fistularin-3 and (+)-11-epi-fistularin-3 by microscale LCMS-Marfey's analysis. Journal of natural products 20050601
Marfey's reagent for chiral amino acid analysis: a review. Amino acids 20041201
Chirality determination of unusual amino acids using precolumn derivatization and liquid chromatography-electrospray ionization mass spectrometry. Journal of chromatography. A 20040507
Acid hydrolysis of silk fibroins and determination of the enrichment of isotopically labeled amino acids using precolumn derivatization and high-performance liquid chromatography-electrospray ionization-mass spectrometry. Analytical biochemistry 20021201
High-performance liquid chromatographic enantioseparation of beta-amino acids. Journal of chromatography. A 20010817
Properties