Home Carboxys (2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid

(2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid

CAS No.:
2438-57-5
Catalog Number:
AG0032CH
Molecular Formula:
C5H8FNO2
Molecular Weight:
133.1209
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
95%
In Stock USA
United States
$56
- +
250mg
95%
In Stock USA
United States
$88
- +
1g
97%
In Stock USA
United States
$163
- +
5g
97%
In Stock USA
United States
$538
- +
10g
97%
In Stock USA
United States
$975
- +
Product Description
Catalog Number:
AG0032CH
Chemical Name:
(2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid
CAS Number:
2438-57-5
Molecular Formula:
C5H8FNO2
Molecular Weight:
133.1209
MDL Number:
MFCD02683983
IUPAC Name:
(2S,4S)-4-fluoropyrrolidine-2-carboxylic acid
InChI:
InChI=1S/C5H8FNO2/c6-3-1-4(5(8)9)7-2-3/h3-4,7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
InChI Key:
ZIWHMENIDGOELV-IMJSIDKUSA-N
SMILES:
OC(=O)[C@@H]1C[C@@H](CN1)F
Properties
Complexity:
128  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
133.054g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
133.122g/mol
Monoisotopic Mass:
133.054g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
49.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.3  
Literature
Title Journal
Rational design of protein stability: effect of (2S,4R)-4-fluoroproline on the stability and folding pathway of ubiquitin. PloS one 20110101
Thermodynamic consequences of incorporating 4-substituted proline derivatives into a small helical protein. Biochemistry 20100518
Stereoelectronic effects on the transition barrier of polyproline conformational interconversion. Protein science : a publication of the Protein Society 20090901
Direct and continuous assay for prolyl 4-hydroxylase. Analytical biochemistry 20090315
Conformational preferences of substrates for human prolyl 4-hydroxylase. Biochemistry 20080909
Stereoelectronic effects on polyproline conformation. Protein science : a publication of the Protein Society 20060101
A stereoelectronic effect on turn formation due to proline substitution in elastin-mimetic polypeptides. Journal of the American Chemical Society 20051228
Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association. Journal of the American Chemical Society 20051116
Substituted 2-azabicyclo[2.1.1]hexanes as constrained proline analogues: implications for collagen stability. The Journal of organic chemistry 20041210
Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers. Journal of the American Chemical Society 20030806
Properties