Home Other Building Blocks 3,3'-Diiodo-l-thyronine

3,3'-Diiodo-l-thyronine

CAS No.:
4604-41-5
Catalog Number:
AG0032CC
Molecular Formula:
C15H13I2NO4
Molecular Weight:
525.0770
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥95%
1 week
United States
$194
- +
5mg
≥95%
1 week
United States
$668
- +
10mg
≥95%
1 week
United States
$1126
- +
Product Description
Catalog Number:
AG0032CC
Chemical Name:
3,3'-Diiodo-l-thyronine
CAS Number:
4604-41-5
Molecular Formula:
C15H13I2NO4
Molecular Weight:
525.0770
MDL Number:
MFCD01863378
IUPAC Name:
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
InChI:
InChI=1S/C15H13I2NO4/c16-10-7-9(2-3-13(10)19)22-14-4-1-8(5-11(14)17)6-12(18)15(20)21/h1-5,7,12,19H,6,18H2,(H,20,21)/t12-/m0/s1
InChI Key:
CPCJBZABTUOGNM-LBPRGKRZSA-N
SMILES:
OC(=O)[C@H](Cc1ccc(c(c1)I)Oc1ccc(c(c1)I)O)N
EC Number:
225-005-7
UNII:
3L9U2Z4602
Properties
Complexity:
385  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
524.893g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
525.081g/mol
Monoisotopic Mass:
524.893g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
92.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.1  
Literature
Title Journal
Analysis of thyroid hormones in serum of Baikal seals and humans by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and immunoassay methods: application of the LC-MS/MS method to wildlife tissues. Environmental science & technology 20111201
Modulation of thyroid hormone concentrations in serum of rats coadministered with perchlorate and iodide-deficient diet. Archives of environmental contamination and toxicology 20110701
Determination of six thyroid hormones in the brain and thyroid gland using isotope-dilution liquid chromatography/tandem mass spectrometry. Analytical chemistry 20110101
Primary and secondary thyroid hormone transporters. Thyroid research 20110101
A method for the analysis of six thyroid hormones in thyroid gland by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100701
Thyroid hormone transport by the human monocarboxylate transporter 8 and its rate-limiting role in intracellular metabolism. Molecular endocrinology (Baltimore, Md.) 20061101
The role of thyroid hormone therapy in acutely ill cardiac patients. Critical care (London, England) 20050101
Measurement of 3,3'-diiodothyronine sulfate (T2S) in thyroidal and nonthyroidal disease, pregnancy, and fetal/neonatal life. Metabolism: clinical and experimental 20041001
Inhibition of the activity of the native gamma-aminobutyric acid A receptor by metabolites of thyroid hormones: correlations with molecular modeling studies. Brain research 20040409
A radioimmunoassay for measurement of 3,3'-diiodothyronine sulfate: Studies in thyroidal and nonthyroidal diseases, pregnancy, and fetal/neonatal life. Metabolism: clinical and experimental 20040401
Comparative evaluation of 11 scoring functions for molecular docking. Journal of medicinal chemistry 20030605
Uptake of triiodothyronine and triiodothyroacetic acid in neonatal rat cardiomyocytes: effects of metabolites and analogs. The Journal of endocrinology 20020501
Characterization of iodothyronine sulfatase activities in human and rat liver and placenta. Endocrinology 20020301
Characterization of uptake and compartmentalization of 3,5,3'-tri-iodothyronine in cultured neonatal rat cardiomyocytes. The Journal of endocrinology 20011001
3,3'-Diiodothyronine sulfate excretion in maternal urine reflects fetal thyroid function in sheep. Pediatric research 20010901
Molecular cloning, expression, and characterization of a canine sulfotransferase that is a human ST1B2 ortholog. Archives of biochemistry and biophysics 20010601
Sulfation of thyroid hormone and dopamine during human development: ontogeny of phenol sulfotransferases and arylsulfatase in liver, lung, and brain. The Journal of clinical endocrinology and metabolism 20010601
Properties