(±)-Blebbistatin
| Title | Journal |
|---|---|
| A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative. | Scientific reports 20160101 |
| Temporal analysis of vascular smooth muscle cell elasticity and adhesion reveals oscillation waveforms that differ with aging. | Aging cell 20121001 |
| Modifications of mechanoelectric feedback induced by 2,3-butanedione monoxime and Blebbistatin in Langendorff-perfused rabbit hearts. | Acta physiologica (Oxford, England) 20120901 |
| Contractility in type III cochlear fibrocytes is dependent on non-muscle myosin II and intercellular gap junctional coupling. | Journal of the Association for Research in Otolaryngology : JARO 20120801 |
| Interventricular heterogeneity as a substrate for arrhythmogenesis of decoupled mitochondria during ischemia in the whole heart. | American journal of physiology. Heart and circulatory physiology 20120715 |
| Cytoskeletal modulation of lipid interactions regulates Lck kinase activity. | The Journal of biological chemistry 20120713 |
| Blebbistatin, a myosin inhibitor, is phototoxic to human cancer cells under exposure to blue light. | Biochimica et biophysica acta 20120701 |
| LTP induction translocates cortactin at distant synapses in wild-type but not Fmr1 knock-out mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120523 |
| Enrichment of cell populations in metaphase, anaphase, and telophase by synchronization using nocodazole and blebbistatin: a novel method suitable for examining dynamic changes in proteins during mitotic progression. | European journal of cell biology 20120501 |
| Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells. | Integrative biology : quantitative biosciences from nano to macro 20120401 |
| Inhibition of actin dynamics during epithelial-to-mesenchymal transition. | Biochemical and biophysical research communications 20120309 |
| Myosin II activity regulates neurite outgrowth and guidance in response to chondroitin sulfate proteoglycans. | Journal of neurochemistry 20120301 |
| Enucleation of human erythroblasts involves non-muscle myosin IIB. | Blood 20120126 |
| Smooth muscle myosin expression, isoform composition, and functional activities in rat corpus cavernosum altered by the streptozotocin-induced type 1 diabetes. | American journal of physiology. Endocrinology and metabolism 20120101 |
| The role of dynamic instability and wavelength in arrhythmia maintenance as revealed by panoramic imaging with blebbistatin vs. 2,3-butanedione monoxime. | American journal of physiology. Heart and circulatory physiology 20120101 |
| Pre-power-stroke cross-bridges contribute to force transients during imposed shortening in isolated muscle fibers. | PloS one 20120101 |
| Mechanics regulates fate decisions of human embryonic stem cells. | PloS one 20120101 |
| Involvement of actin filament in the generation of Ca2+ mobilizing messengers in glucose-induced Ca2+ signaling in pancreatic β-cells. | Islets 20120101 |
| [A single E726Q mutation in the membrane proximal α-helix of integrin β3 subunit induces membrane blebbing by disrupting the membrane-actin cortex interaction]. | Zhongguo shi yan xue ye xue za zhi 20111201 |
| LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. | Journal of cellular physiology 20111101 |
| Non-muscle myosin IIA is required for the development of the zebrafish glomerulus. | Kidney international 20111101 |
| Dynamic changes of acoustic load and complex impedance as reporters for the cytotoxicity of small molecule inhibitors. | Chemical research in toxicology 20110919 |
| Titin based viscosity in ventricular physiology: an integrative investigation of PEVK-actin interactions. | Journal of molecular and cellular cardiology 20110901 |
| Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes. | Nature cell biology 20110828 |
| Drifting motions of the adenovirus receptor CAR and immobile integrins initiate virus uncoating and membrane lytic protein exposure. | Cell host & microbe 20110818 |
| Inhibition of suicidal erythrocyte death by blebbistatin. | American journal of physiology. Cell physiology 20110801 |
| Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. | The Biochemical journal 20110715 |
| Real-time cellular impedance measurements detect Ca(2+) channel-dependent oscillations of morphology in human H295R adrenoma cells. | Biochimica et biophysica acta 20110501 |
| Rho signaling pathway and apical constriction in the early lens placode. | Genesis (New York, N.Y. : 2000) 20110501 |
| Distinct cytoskeleton populations and extensive crosstalk control Ciona notochord tubulogenesis. | Development (Cambridge, England) 20110401 |
| Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins. | EMBO reports 20110303 |
| Correlation of dysfunction of nonmuscle myosin IIA with increased induction of Cyp1a1 in Hepa-1 cells. | Biochimica et biophysica acta 20110301 |
| Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A. | Cancer cell 20110118 |
| In vitro and in vivo relaxation of urinary bladder smooth muscle by the selective myosin II inhibitor, blebbistatin. | BJU international 20110101 |
| Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101 |
| Blebbing dynamics during endothelial cell spreading. | European journal of cell biology 20110101 |
| Blebbistain, a myosin II inhibitor, as a novel strategy to regulate detrusor contractility in a rat model of partial bladder outlet obstruction. | PloS one 20110101 |
| Myosin II activity dependent and independent vinculin recruitment to the sites of E-cadherin-mediated cell-cell adhesion. | BMC cell biology 20110101 |
| The elementary events underlying force generation in neuronal lamellipodia. | Scientific reports 20110101 |
| Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Vesicle trafficking plays a novel role in erythroblast enucleation. | Blood 20101028 |
| Dupuytren's fibroblast contractility by sphingosine-1-phosphate is mediated through non-muscle myosin II. | The Journal of hand surgery 20101001 |
| Non-muscle myosin II regulates survival threshold of pluripotent stem cells. | Nature communications 20100907 |
| Effect of nonuniform muscle contraction on sustainability and frequency of triggered arrhythmias in rat cardiac muscle. | Circulation 20100629 |
| Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase. | American journal of physiology. Cell physiology 20100601 |
| Myosin II contributes to cell-scale actin network treadmilling through network disassembly. | Nature 20100520 |
| The kinetics of force-induced cell reorganization depend on microtubules and actin. | Cytoskeleton (Hoboken, N.J.) 20100401 |
| Blebbistatin effectively uncouples the excitation-contraction process in zebrafish embryonic heart. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100301 |
| Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis. | Experimental cell research 20100115 |
| Myosin IIB isoform plays an essential role in the formation of two distinct types of macropinosomes. | Cytoskeleton (Hoboken, N.J.) 20100101 |
| Blebbistatin inhibits contraction and accelerates migration in mouse hepatic stellate cells. | British journal of pharmacology 20100101 |
| Reversible bleb formation in mast cells stimulated with antigen is Ca2+/calmodulin-dependent and bleb size is regulated by ARF6. | The Biochemical journal 20091214 |
| On the origins of the universal dynamics of endogenous granules in mammalian cells. | Molecular & cellular biomechanics : MCB 20091201 |
| Stabilization of anaphase midzone microtubules is regulated by Rho during cytokinesis in human fibrosarcoma cells. | Experimental cell research 20091001 |
| In vitro and in vivo relaxation of corpus cavernosum smooth muscle by the selective myosin II inhibitor, blebbistatin. | The journal of sexual medicine 20091001 |
| Cortical F-actin, the exocytic mode, and neuropeptide release in mouse chromaffin cells is regulated by myristoylated alanine-rich C-kinase substrate and myosin II. | Molecular biology of the cell 20090701 |
| 'Injecting' yeast. | Nature methods 20090701 |
| Megalin and nonmuscle myosin heavy chain IIA interact with the adaptor protein Disabled-2 in proximal tubule cells. | Kidney international 20090601 |
| The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA. | Journal of cell science 20090515 |
| Stabilization of helical order in the thick filaments by blebbistatin: further evidence of coexisting multiple conformations of myosin. | Biophysical journal 20090506 |
| Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis. | Investigative ophthalmology & visual science 20090501 |
| Roles of focal adhesions and fibronectin-mediated cohesion in proliferation of confluent fibroblasts. | Journal of cellular physiology 20090401 |
| Programmed subcellular release for studying the dynamics of cell detachment. | Nature methods 20090301 |
| F-actin and myosin II accelerate catecholamine release from chromaffin granules. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090121 |
| Panoramic imaging reveals basic mechanisms of induction and termination of ventricular tachycardia in rabbit heart with chronic infarction: implications for low-voltage cardioversion. | Heart rhythm 20090101 |
| The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellular calcium wave propagation in corneal endothelial cells. | Investigative ophthalmology & visual science 20081101 |
| Dual role for myosin II in GLUT4-mediated glucose uptake in 3T3-L1 adipocytes. | Experimental cell research 20081015 |
| Blebbistatin stabilizes the helical order of myosin filaments by promoting the switch 2 closed state. | Biophysical journal 20081001 |
| The translocation of signaling molecules in dark adapting mammalian rod photoreceptor cells is dependent on the cytoskeleton. | Cell motility and the cytoskeleton 20081001 |
| Extracellular matrix rigidity promotes invadopodia activity. | Current biology : CB 20080909 |
| Propofol causes neurite retraction in neurones. | British journal of anaesthesia 20080901 |
| Regulation of polarity in cells devoid of actin bundle system after treatment with inhibitors of myosin II activity. | Cell motility and the cytoskeleton 20080901 |
| Plectin deposition at podosome rings requires myosin contractility. | Cell motility and the cytoskeleton 20080801 |
| Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth. | Blood 20080701 |
| Roles of basolateral solute uptake via NKCC1 and of myosin II in vasopressin-induced cell swelling in inner medullary collecting duct. | American journal of physiology. Renal physiology 20080701 |
| Myosin II regulates the shape of three-dimensional intestinal epithelial cysts. | Journal of cell science 20080601 |
| Blebbistatin inhibits the chemotaxis of vascular smooth muscle cells by disrupting the myosin II-actin interaction. | American journal of physiology. Heart and circulatory physiology 20080501 |
| Images in cardiovascular medicine. Optical mapping of the human atrioventricular junction. | Circulation 20080318 |
| Blebbistatin: use as inhibitor of muscle contraction. | Pflugers Archiv : European journal of physiology 20080301 |
| A cytoskeletal demolition worker: myosin II acts as an actin depolymerization agent. | Journal of molecular biology 20080111 |
| Atrial cardiomyocyte tachycardia alters cardiac fibroblast function: a novel consideration in atrial remodeling. | Cardiovascular research 20071201 |
| Myosin II and Rho kinase activity are required for melanosome aggregation in fish retinal pigment epithelial cells. | Cell motility and the cytoskeleton 20071101 |
| Attenuation of actinomyosinII contractile activity in growth cones accelerates filopodia-guided and microtubule-based neurite elongation. | Brain research 20071024 |
| Membrane associated nonmuscle myosin II functions as a motor for actin-based vesicle transport in clam oocyte extracts. | Cell motility and the cytoskeleton 20071001 |
| Forced unfolding of proteins within cells. | Science (New York, N.Y.) 20070803 |
| Hepatic stellate cell protrusions couple platelet-derived growth factor-BB to chemotaxis. | Hepatology (Baltimore, Md.) 20070601 |
| Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk. | Nature cell biology 20070301 |
| Association of CD38 with nonmuscle myosin heavy chain IIA and Lck is essential for the internalization and activation of CD38. | The Journal of biological chemistry 20070223 |
| Analysis of mitotic phosphorylation of borealin. | BMC cell biology 20070101 |
| A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions. | PloS one 20070101 |
| Blebbistatin inhibits sphingosylphosphorylcholine-induced contraction of collagen-gel fiber populated by vascular smooth-muscle cells. | Journal of pharmacological sciences 20061101 |
| Myosin-based contraction is not necessary for cardiac c-looping in the chick embryo. | Anatomy and embryology 20061001 |
| Myosin light chain kinase plays a role in the regulation of epithelial cell survival. | Journal of cell science 20060601 |
| Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation. | Experimental cell research 20060515 |
| Catch force links and the low to high force transition of myosin. | Biophysical journal 20060501 |
| The interaction of Phe472 with a fluorescent inhibitor bound to the complex of myosin subfragment-1 with nucleotide. | Biochemistry 20060131 |
| Antagonists of myosin light chain kinase and of myosin II inhibit specific events of egg activation in fertilized mouse eggs. | Biology of reproduction 20060101 |
| Rho kinase regulates fragmentation and phagocytosis of apoptotic cells. | Experimental cell research 20060101 |
| Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts. | Molecular biology of the cell 20051001 |
| Redundant mechanisms for anaphase chromosome movements: crane-fly spermatocyte spindles normally use actin filaments but also can function without them. | Protoplasma 20051001 |
| Myosin II regulatory light chain is required for trafficking of bile salt export protein to the apical membrane in Madin-Darby canine kidney cells. | The Journal of biological chemistry 20050624 |
| A novel role for myosin II in insulin-stimulated glucose uptake in 3T3-L1 adipocytes. | Biochemical and biophysical research communications 20050617 |
| NCAM 180 acting via a conserved C-terminal domain and MLCK is essential for effective transmission with repetitive stimulation. | Neuron 20050616 |
| Cortical actin turnover during cytokinesis requires myosin II. | Current biology : CB 20050426 |
| A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050330 |
| Rho-kinase and myosin II activities are required for cell type and environment specific migration. | Genes to cells : devoted to molecular & cellular mechanisms 20050201 |
| Myosin regulation in the migration of tumor cells and leukocytes within a three-dimensional collagen matrix. | Cellular and molecular life sciences : CMLS 20050101 |
| Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure. | BMC cell biology 20050101 |
| Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041124 |
| Kinetic mechanism of blebbistatin inhibition of nonmuscle myosin IIb. | Biochemistry 20041123 |
| Cell type-specific regulation of RhoA activity during cytokinesis. | The Journal of biological chemistry 20041022 |
| Mechanism of blebbistatin inhibition of myosin II. | The Journal of biological chemistry 20040820 |
| Inhibition of pancreatic adenocarcinoma cellular invasiveness by blebbistatin: a novel myosin II inhibitor. | Biochemical and biophysical research communications 20040123 |
| Specificity of blebbistatin, an inhibitor of myosin II. | Journal of muscle research and cell motility 20040101 |
| Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. | Science (New York, N.Y.) 20030314 |