Home Aminos 1,4-Bis(3-aminopropyl)piperazine

1,4-Bis(3-aminopropyl)piperazine

CAS No.:
7209-38-3
Catalog Number:
AG003286
Molecular Formula:
C10H24N4
Molecular Weight:
200.3244
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Product Description
Catalog Number:
AG003286
Chemical Name:
1,4-Bis(3-aminopropyl)piperazine
CAS Number:
7209-38-3
Molecular Formula:
C10H24N4
Molecular Weight:
200.3244
MDL Number:
MFCD00006161
IUPAC Name:
3-[4-(3-aminopropyl)piperazin-1-yl]propan-1-amine
InChI:
InChI=1S/C10H24N4/c11-3-1-5-13-7-9-14(10-8-13)6-2-4-12/h1-12H2
InChI Key:
XUSNPFGLKGCWGN-UHFFFAOYSA-N
SMILES:
NCCCN1CCN(CC1)CCCN
EC Number:
230-589-1
UNII:
7GVX6C734B
Properties
Complexity:
116  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
200.2g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
200.33g/mol
Monoisotopic Mass:
200.2g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
58.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.4  
Literature
Title Journal
Retraction notice to 'Layer silicates modified with 1,4-bis(3-aminopropyl)piperazine for the removal of Th(IV), U(VI) and Eu(III) from aqueous media' [J. Hazard. Mater. 171 (2009) 514-523]. Journal of hazardous materials 20111030
New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity--Part II. European journal of medicinal chemistry 20110601
Synthesis and in vitro biological evaluation of new polyamine conjugates as potential anticancer drugs. European journal of medicinal chemistry 20101201
Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine. Bioorganic & medicinal chemistry 20100715
Layer silicates modified with 1,4-bis(3-aminopropyl)piperazine for the removal of Th(IV), U(VI) and Eu(III) from aqueous media. Journal of hazardous materials 20091115
Designed pendant chain covalently bonded to analogue of heulandite for removal of divalent toxic metals from aqueous solution: thermodynamic and equilibrium study. Journal of colloid and interface science 20090901
Synthesis, characterization, and properties of organically templated lanthanide oxalatophosphates with a three-dimensional honeycomb structure: (H4APPIP)[Ln3(C2O4)(5.5)(H2PO4)2].5H2O (Ln = Er-Lu, APPIP = 1,4-bis(3-aminopropyl)piperazine). Inorganic chemistry 20090216
New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity. Bioorganic & medicinal chemistry 20081015
Synthesis and preliminary evaluation of new ursolic and oleanolic acids derivatives as antileishmanial agents. Journal of enzyme inhibition and medicinal chemistry 20081001
Designed pendant chain covalently bonded to silica gel for cation removal. Journal of hazardous materials 20080815
Synthesis, structure, and polymorphism studies in amine-templated open-framework zinc phosphites. Inorganic chemistry 20080616
Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents. Bioorganic & medicinal chemistry 20080115
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling. Bioorganic & medicinal chemistry letters 20070701
One pot synthesis of pyrimidine and bispyrimidine derivatives and their evaluation for anti-inflammatory and analgesic activities. Bioorganic & medicinal chemistry 20070515
[Thieno[3,2-c]quinoline-4-yl-amines--synthesis and investigation of activity against malaria]. Die Pharmazie 20060401
1,4-bis(3-aminopropyl)piperazine libraries: from the discovery of classical chloroquine-like antimalarials to the identification of new targets. Combinatorial chemistry & high throughput screening 20050201
Synthesis, antimalarial activity, and molecular modeling of new pyrrolo[1,2-a]quinoxalines, bispyrrolo[1,2-a]quinoxalines, bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and bispyrrolo[1,2-a]thieno[3,2-e]pyrazines. Journal of medicinal chemistry 20040408
Synthesis and antimalarial evaluation of new 1,4-bis(3-aminopropyl)piperazine derivatives. Bioorganic & medicinal chemistry letters 20031103
Recent news related to substrates and inhibitors of plant amine oxidases. Biochimica et biophysica acta 20030411
Synthesis and in vitro and in vivo antimalarial activity of N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine derivatives. Journal of medicinal chemistry 20030213
Properties