Phosphoric acid, diethyl 4-nitrophenyl ester
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Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques. | Toxicology letters 20180901 |
The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE. | Chemico-biological interactions 20180801 |
New therapeutic approaches and novel alternatives for organophosphate toxicity. | Toxicology letters 20180701 |
Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor. | Chemico-biological interactions 20170825 |
Effects of organophosphates on the regulation of mesenchymal stem cell proliferation and differentiation. | Chemico-biological interactions 20170325 |
High concentration of trichlorfon (1mM) disrupts axonal cytoskeleton and decreases the expression of plasticity-related proteins in SH-SY5Y cells. | Toxicology in vitro : an international journal published in association with BIBRA 20170301 |
Butyrylcholinesterase identification in a phenylvalerate esterase-enriched fraction sensitive to low mipafox concentrations in chicken brain. | Archives of toxicology 20170201 |
Alterations in mRNA and protein expression of glutamate transporters in rat hippocampus after paraoxon exposure. | Neurotoxicology 20161201 |
Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells. | Chemico-biological interactions 20161125 |
A new post-intoxication treatment of paraoxon and parathion poisonings using an evolved PON1 variant and recombinant GOT1. | Chemico-biological interactions 20161125 |
Effects of antiretroviral treatment on paraoxonase 1 (PON1) activity in rats. | Chemico-biological interactions 20161125 |
Modulation of paraoxonase 1 (PON1) activity and protein N-homocysteinylation by bisphosphonates in rats. | Chemico-biological interactions 20161125 |
Pyridoxal oxime derivative potency to reactivate cholinesterases inhibited by organophosphorus compounds. | Toxicology letters 20161116 |
Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies. | Neurotoxicology 20160501 |
Comparison of inhibition kinetics of several organophosphates, including some nerve agent surrogates, using human erythrocyte and rat and mouse brain acetylcholinesterase. | Toxicology letters 20160425 |
Esterase detoxication of acetylcholinesterase inhibitors using human liver samples in vitro. | Toxicology 20160415 |
Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches. | Archives of toxicology 20160301 |
Intranasal delivery of obidoxime to the brain prevents mortality and CNS damage from organophosphate poisoning. | Neurotoxicology 20160301 |
Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase. | Toxicology letters 20160226 |
A novel expression cassette delivers efficient production of exclusively tetrameric human butyrylcholinesterase with improved pharmacokinetics for protection against organophosphate poisoning. | Biochimie 20151101 |
Allele frequencies of PON1 Q192R polymorphism in four populations of India. | Environmental toxicology and pharmacology 20150501 |
Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase. | Archives of toxicology 20150301 |
The cannabinoid receptor antagonist AM251 increases paraoxon and chlorpyrifos oxon toxicity in rats. | Neurotoxicology 20150101 |
Paraoxonase 1 polymorphisms within a Mississippi USA population as possible biomarkers of enzyme activities associated with disease susceptibility. | Biochemical genetics 20141201 |
Effects of toxicologically relevant xenobiotics and the lipid-derived electrophile 4-hydroxynonenal on macrophage cholesterol efflux: silencing carboxylesterase 1 has paradoxical effects on cholesterol uptake and efflux. | Chemical research in toxicology 20141020 |
Prevention of organophosphate-induced chronic epilepsy by early benzodiazepine treatment. | Toxicology 20140902 |
Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication. | Neurotoxicology 20140901 |
Developmental exposure to the polybrominated diphenyl ether PBDE 209: Neurobehavioural and neuroprotein analysis in adult male and female mice. | Environmental toxicology and pharmacology 20140901 |
Oxidative stress resulting from exposure of a human salivary gland cells to paraoxon: an in vitro model for organophosphate oral exposure. | Toxicology in vitro : an international journal published in association with BIBRA 20140801 |
Investigation of evolved paraoxonase-1 variants for prevention of organophosphorous pesticide compound intoxication. | The Journal of pharmacology and experimental therapeutics 20140601 |
Purification of Holstein bull semen paraoxonase 1 (PON1) by hydrophobic interaction chromatography and investigation of its inhibition kinetics by heavy metals. | Biological trace element research 20140401 |
Protection against paraoxon toxicity by an intravenous pretreatment with polyethylene-glycol-conjugated recombinant butyrylcholinesterase in macaques. | Chemico-biological interactions 20140305 |
Interactions between xylene-linked carbamoyl bis-pyridinium mono-oximes and organophosphates inhibited-AChE: a kinetic study. | Toxicology 20140227 |
In vitro reactivation kinetics of paraoxon- and DFP-inhibited electric eel AChE using mono- and bis-pyridinium oximes. | Archives of toxicology 20140201 |
Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox. | International journal of molecular sciences 20140101 |
Sub-chronic exposure to paraoxon neither induces nor exacerbates diabetes mellitus in Wistar rat. | Journal of applied toxicology : JAT 20131001 |
Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates. | Chemico-biological interactions 20130325 |
Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents. | Chemico-biological interactions 20130325 |
Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques. | Chemico-biological interactions 20130325 |
In vitro investigation of efficacy of new reactivators on OPC inhibited rat brain acetylcholinesterase. | Chemico-biological interactions 20130325 |
Alteration of the expression of pesticide-metabolizing enzymes in pregnant mice: potential role in the increased vulnerability of the developing brain. | Drug metabolism and disposition: the biological fate of chemicals 20130201 |
Adverse outcome pathways during zebrafish embryogenesis: a case study with paraoxon. | Aquatic toxicology (Amsterdam, Netherlands) 20130115 |
Acetylcholinesterase of the sand fly, Phlebotomus papatasi (Scopoli): cDNA sequence, baculovirus expression, and biochemical properties. | Parasites & vectors 20130101 |
Regulation of CYP3A genes by glucocorticoids in human lung cells. | F1000Research 20130101 |
R-carrying genotypes of serum paraoxonase (PON1) 192 polymorphism and higher activity ratio are related to susceptibility against ischemic stroke. | Molecular biology reports 20121201 |
Towards an integrated biosensor array for simultaneous and rapid multi-analysis of endocrine disrupting chemicals. | Analytica chimica acta 20121102 |
Early in vivo MR spectroscopy findings in organophosphate-induced brain damage-potential biomarkers for short-term survival. | Magnetic resonance in medicine 20121101 |
Paraoxonase 1 (PON1) as a marker of short term death in breast cancer recurrence. | Clinical biochemistry 20121101 |
Cholinesterase and paraoxonase (PON1) enzyme activities in Mexican-American mothers and children from an agricultural community. | Journal of exposure science & environmental epidemiology 20121101 |
Covalent inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by the carbamates JZL184 and URB597. | Biochemical pharmacology 20121101 |
Studies of the interaction of two organophosphonates with nanostructured silver surfaces. | The Analyst 20121007 |
Detoxification of organophosphate residues using phosphotriesterase and their evaluation using flow based biosensor. | Analytica chimica acta 20121001 |
In vitro skin permeation and decontamination of the organophosphorus pesticide paraoxon under various physical conditions--evidence for a wash-in effect. | Toxicology mechanisms and methods 20120901 |
Characterization of status epilepticus induced by two organophosphates in rats. | Epilepsy research 20120901 |
Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity. | Toxicology 20120816 |
4-nitrophenol surface molecularly imprinted polymers based on multiwalled carbon nanotubes for the elimination of paraoxon pollution. | Journal of hazardous materials 20120815 |
Organophosphorus compound effects on neurotrophin receptors and intracellular signaling. | Toxicology in vitro : an international journal published in association with BIBRA 20120801 |
Hydrolysis of phosphotriesters: a theoretical analysis of the enzymatic and solution mechanisms. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120727 |
NTE and non-NTE esterases in brain membrane: kinetic characterization with organophosphates. | Toxicology 20120716 |
Pralidoxime inhibits paraoxon-induced depression of rocuronium-neuromuscular block in a time-dependent fashion. | The American journal of emergency medicine 20120701 |
Decreased paraoxonase 1 (PON1) lactonase activity in hemodialyzed and renal transplanted patients. A novel cardiovascular biomarker in end-stage renal disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120701 |
The effect of age on the paraoxonase and arylesterase activity of pregnant mothers and their infants. | Journal of clinical laboratory analysis 20120701 |
Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20120615 |
Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase--Structure-activity relationships. | Biochemical pharmacology 20120615 |
A molecularly imprinted polymer based on functionalized multiwalled carbon nanotubes for the electrochemical detection of parathion-methyl. | The Analyst 20120607 |
Using MRI for the assessment of paraoxon-induced brain damage and efficacy of antidotal treatment. | Journal of applied toxicology : JAT 20120601 |
Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima. | Proteins 20120601 |
Interactions of organophosphates with keratins in the cornified epithelium of human skin. | Chemico-biological interactions 20120530 |
Metabolic activation of prasugrel: nature of the two competitive pathways resulting in the opening of its thiophene ring. | Chemical research in toxicology 20120521 |
Polyethylene glycosylation prolongs the stability of recombinant human paraoxonase-1. | Toxicology letters 20120505 |
Kinetics of inhibition of soluble peripheral nerve esterases by PMSF: a non-stable compound that potentiates the organophosphorus-induced delayed neurotoxicity. | Archives of toxicology 20120501 |
Acetylcholinesterase of Haematobia irritans (Diptera: Muscidae): baculovirus expression, biochemical properties, and organophosphate insensitivity of the G262A mutant. | Journal of medical entomology 20120501 |
Identification of phosphorylated butyrylcholinesterase in human plasma using immunoaffinity purification and mass spectrometry. | Analytica chimica acta 20120420 |
Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases. | The Journal of biological chemistry 20120406 |
Serum paraoxonase phenotype distribution in exudative age-related macular degeneration and its relationship to homocysteine and oxidized low-density lipoprotein. | Retina (Philadelphia, Pa.) 20120401 |
Heterogeneous reactions of suspended parathion, malathion, and fenthion particles with NO(3) radicals. | Chemosphere 20120401 |
Probing the simulant behavior of PNPDPP toward parathion and paraoxon: a computational study. | Journal of molecular graphics & modelling 20120401 |
Serum paraoxonase and arylesterase activities in Iranian patients with nonalcoholic fatty liver disease. | Pathophysiology : the official journal of the International Society for Pathophysiology 20120401 |
Transcription and induction profiles of three novel P450 genes in Liposcelis bostrychophila (Psocoptera: Liposcelididae). | Journal of economic entomology 20120401 |
Affinity binding-guided fluorescent nanobiosensor for acetylcholinesterase inhibitors via distance modulation between the fluorophore and metallic nanoparticle. | Analytical chemistry 20120320 |
Comparative kinetics of organophosphates and oximes with erythrocyte, muscle and brain acetylcholinesterase. | Toxicology letters 20120307 |
Degradation and elimination of succinylcholine and succinylmonocholine and definition of their respective detection windows in blood and urine for forensic purposes. | International journal of legal medicine 20120301 |
Nano-intercalated organophosphorus-hydrolyzing enzymes in organophosphorus antagonism. | AAPS PharmSciTech 20120301 |
Acetylcholinesterase of Stomoxys calcitrans (L.) (Diptera: Muscidae): cDNA sequence, baculovirus expression, and biochemical properties. | Veterinary parasitology 20120227 |
Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases. | Archives of medical science : AMS 20120227 |
Highly sensitive and selective immuno-capture/electrochemical assay of acetylcholinesterase activity in red blood cells: a biomarker of exposure to organophosphorus pesticides and nerve agents. | Environmental science & technology 20120207 |
Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran. | Chemico-biological interactions 20120205 |
Nicotinic stimulation induces Tristetraprolin over-production and attenuates inflammation in muscle. | Biochimica et biophysica acta 20120201 |
Docking and molecular dynamics simulation studies on glycation-induced conformational changes of human paraoxonase 1. | European biophysics journal : EBJ 20120201 |
A para-nitrophenol phosphonate probe labels distinct serine hydrolases of Arabidopsis. | Bioorganic & medicinal chemistry 20120115 |
Effects of acetylcholinesterase inhibitor paraoxon denote the possibility of non-quantal acetylcholine release in myocardium of different vertebrates. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20120101 |
Immunomodulation by poly-YE reduces organophosphate-induced brain damage. | Brain, behavior, and immunity 20120101 |
Low levels of serum paraoxonase activities are characteristic of metabolic syndrome and may influence the metabolic-syndrome-related risk of coronary artery disease. | Experimental diabetes research 20120101 |
Pyridostigmine bromide protection against acetylcholinesterase inhibition by pesticides. | Journal of biochemical and molecular toxicology 20120101 |
Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon. | Toxicology and applied pharmacology 20120101 |
Identification of differentially expressed genes in SHSY5Y cells exposed to okadaic acid by suppression subtractive hybridization. | BMC genomics 20120101 |
PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways. | PPAR research 20120101 |
Organophosphorus hydrolase: a multifaceted plant genetic marker which is selectable, scorable, and quantifiable in whole seed. | Methods in molecular biology (Clifton, N.J.) 20120101 |
Analytical approaches for monitoring exposure to organophosphorus and carbamate agents through analysis of protein adducts. | Drug testing and analysis 20120101 |
Photostability of antidotal oxime HI-6, impact on drug development. | Drug testing and analysis 20120101 |
Recent advances in polymeric materials used as electron mediators and immobilizing matrices in developing enzyme electrodes. | Sensors (Basel, Switzerland) 20120101 |
Forskolin and derivatives as tools for studying the role of cAMP. | Die Pharmazie 20120101 |
The level of DING proteins is increased in HIV-infected patients: in vitro and in vivo studies. | PloS one 20120101 |
Enhancement of anti-cholinesterase activity of aqueous samples by hypochlorite oxidation for monitoring traces of organophosphorus pesticides in water. | The Journal of toxicological sciences 20120101 |
Antihyperglycemic and antioxidative effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in mice fed with a high fat diet. | International journal of molecular sciences 20120101 |
Mineralization of acephate, a recalcitrant organophosphate insecticide is initiated by a pseudomonad in environmental samples. | PloS one 20120101 |
Complex control of GABA(A) receptor subunit mRNA expression: variation, covariation, and genetic regulation. | PloS one 20120101 |
Vasculitis, Atherosclerosis, and Altered HDL Composition in Heme-Oxygenase-1-Knockout Mice. | International journal of hypertension 20120101 |
Application of physiologically based pharmacokinetic models in chemical risk assessment. | Journal of toxicology 20120101 |
Paraoxonase 1 in chronic kidney failure. | Journal of lipids 20120101 |
Optical detection of organophosphorus compounds based on Mn-doped ZnSe d-dot enzymatic catalytic sensor. | Biosensors & bioelectronics 20120101 |
Lipid peroxidation and paraoxonase-1 activity in celiac disease. | Journal of lipids 20120101 |
Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease. | International journal of hepatology 20120101 |
Novel associations of nonstructural Loci with paraoxonase activity. | Journal of lipids 20120101 |
Paraoxonase 1 polymorphism and prenatal pesticide exposure associated with adverse cardiovascular risk profiles at school age. | PloS one 20120101 |
Additional Common Polymorphisms in the PON Gene Cluster Predict PON1 Activity but Not Vascular Disease. | Journal of lipids 20120101 |
Increased Levels of Human Carotid Lesion Linoleic Acid Hydroperoxide in Symptomatic and Asymptomatic Patients Is Inversely Correlated with Serum HDL and Paraoxonase 1 Activity. | Journal of lipids 20120101 |
Purification and characterization of a novel chlorpyrifos hydrolase from Cladosporium cladosporioides Hu-01. | PloS one 20120101 |
Conformational variability of organophosphorus hydrolase upon soman and paraoxon binding. | The journal of physical chemistry. B 20111229 |
An acetylcholinesterase biosensor for determination of low concentrations of Paraoxon and Dichlorvos. | New biotechnology 20111215 |
Site-specific immobilization of a (His)6-tagged acetylcholinesterase on nickel nanoparticles for highly sensitive toxicity biosensors. | Biosensors & bioelectronics 20111215 |
Relationship of human paraoxonase-1 serum activity and genotype with atherosclerosis in individuals from the Deep South. | Pharmacogenetics and genomics 20111201 |
Polymorphism in the acetylcholinesterase gene of Musca domestica L. field populations in Turkey. | Journal of vector ecology : journal of the Society for Vector Ecology 20111201 |
Reactivation of organophosphate-inhibited human acetylcholinesterase by isonitrosoacetone (MINA): a kinetic analysis. | Chemico-biological interactions 20111115 |
The relationship of PON1 QR 192 and LM 55 polymorphisms with serum paraoxonase activities of Turkish diabetic patients. | Toxicology and industrial health 20111101 |
Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system. | Toxicology and applied pharmacology 20111101 |
His6-OPH enzyme-based bio-hybrid material for organophosphate detection. | Analytical and bioanalytical chemistry 20111101 |
Naringenin is an inhibitor of human serum paraoxonase (PON1): an in vitro study. | Journal of clinical laboratory analysis 20111101 |
Surface-enhanced Raman scattering detection of cholinesterase inhibitors. | Analytica chimica acta 20111010 |
A cembranoid protects acute hippocampal slices against paraoxon neurotoxicity. | Toxicology in vitro : an international journal published in association with BIBRA 20111001 |
Effect of dilution on high-density lipoprotein associated paraoxonase-1 activity. | Clinical biochemistry 20111001 |
High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids. | Annals of the rheumatic diseases 20110901 |
Lateral flow immunochromatographic assay for sensitive pesticide detection by using Fe3O4 nanoparticle aggregates as color reagents. | Analytical chemistry 20110901 |
Cholinesterases, a target of pharmacology and toxicology. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20110901 |
Enhanced refoldability and thermoactivity of fluorinated phosphotriesterase. | Chembiochem : a European journal of chemical biology 20110816 |
Paraoxonase 1 192 and 55 polymorphisms in osteosarcoma. | Molecular biology reports 20110801 |
Relation between methylmercury exposure and plasma paraoxonase activity in inuit adults from Nunavik. | Environmental health perspectives 20110801 |
Acetylcholinesterase biosensor based on single-walled carbon nanotubes--Co phtalocyanine for organophosphorus pesticides detection. | Talanta 20110715 |
Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides. | Medicinal research reviews 20110701 |
Site-specific immobilization of gold binding polypeptide on gold nanoparticle-coated graphene sheet for biosensor application. | Nanoscale 20110701 |
Pitfalls in the assessment of PON1 status in clinical populations. | Fertility and sterility 20110630 |
Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase. | Cell metabolism 20110608 |
New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases. | The Journal of biological chemistry 20110603 |
Mining electron density for functionally relevant protein polysterism in crystal structures. | Cellular and molecular life sciences : CMLS 20110601 |
The crystal structure of the cephalosporin deacetylating enzyme acetyl xylan esterase bound to paraoxon explains the low sensitivity of this serine hydrolase to organophosphate inactivation. | The Biochemical journal 20110601 |
In vitro efficacy of paraoxonase 1 from multiple sources against various organophosphates. | Toxicology in vitro : an international journal published in association with BIBRA 20110601 |
Effects of intronic and exonic polymorphisms of paraoxonase 1 (PON1) gene on serum PON1 activity in a Korean population. | Journal of Korean medical science 20110601 |
Effect of bromine oxidation on high-performance thin-layer chromatography multi-enzyme inhibition assay detection of organophosphates and carbamate insecticides. | Journal of chromatography. A 20110513 |
High risk of cardiovascular disease in iron overload patients. | European journal of clinical investigation 20110501 |
Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period. | Journal of strength and conditioning research 20110501 |
Evaluating pharmacokinetic and pharmacodynamic interactions with computational models in supporting cumulative risk assessment. | International journal of environmental research and public health 20110501 |
A sensitive enzymatic method for paraoxon detection based on enzyme inhibition and fluorescence quenching. | Talanta 20110415 |
Effect of PON1 on dichlorvos toxicokinetics. | Emergency medicine journal : EMJ 20110401 |
Does modulation of organic cation transporters improve pralidoxime activity in an animal model of organophosphate poisoning? | Critical care medicine 20110401 |
Non-quantal release of acetylcholine in guinea-pig airways: role of choline transporter. | Experimental physiology 20110401 |
Electrochemical detection of interaction between Thioflavin T and acetylcholinesterase. | The Analyst 20110321 |
High-fidelity determination of security threats via a Boolean biocatalytic cascade. | Chemical communications (Cambridge, England) 20110321 |
Esterase metabolism of cholinesterase inhibitors using rat liver in vitro. | Toxicology 20110315 |
Effect of different buffers on kinetic properties of human acetylcholinesterase and the interaction with organophosphates and oximes. | Archives of toxicology 20110301 |
Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. | Environmental and molecular mutagenesis 20110301 |
Treatment efficacy in a soman-poisoned guinea pig model: added value of physostigmine? | Archives of toxicology 20110301 |
The effect of paraoxon on spermatogenesis in Dugesia gonocephala from the Chilean Altiplano: proliferation and apoptosis. | Environmental science and pollution research international 20110301 |
Proxidant* antioxidant balance in supplemented elite female volleyball athletes during a six week training period. | The Journal of sports medicine and physical fitness 20110301 |
Performance evaluation of fast Fourier-transform continuous cyclic-voltammetry pesticide biosensor. | Analytica chimica acta 20110221 |
Highly-sensitive organophosphorous pesticide biosensors based on nanostructured films of acetylcholinesterase and CdTe quantum dots. | Biosensors & bioelectronics 20110215 |
Fullerene antioxidants decrease organophosphate-induced acetylcholinesterase inhibition in vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20110201 |
Q192R polymorphism of the paraoxonase-1 gene as a risk factor for obesity in Portuguese women. | European journal of endocrinology 20110201 |
Improving a natural enzyme activity through incorporation of unnatural amino acids. | Journal of the American Chemical Society 20110119 |
Microsomal biotransformation of chlorpyrifos, parathion and fenthion in rainbow trout (Oncorhynchus mykiss) and coho salmon (Oncorhynchus kisutch): mechanistic insights into interspecific differences in toxicity. | Aquatic toxicology (Amsterdam, Netherlands) 20110117 |
Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase. | Toxicology letters 20110115 |
Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking. | Bioorganic & medicinal chemistry 20110115 |
Inhibition with spontaneous reactivation of carboxyl esterases by organophosphorus compounds: paraoxon as a model. | Chemical research in toxicology 20110114 |
Highest paraoxonase turnover rate found in a bacterial phosphotriesterase variant. | Protein engineering, design & selection : PEDS 20110101 |
Purification and characterization of an intracellular lipase from pleopods of whiteleg shrimp (Litopenaeus vannamei). | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20110101 |
Phosphotriesterase variants with high methylphosphonatase activity and strong negative trade-off against phosphotriesters. | Protein engineering, design & selection : PEDS 20110101 |
Differential hydrolysis of homocysteine thiolactone by purified human serum (192)Q and (192)R PON1 isoenzymes. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110101 |
Association analysis of PON2 genetic variants with serum paraoxonase activity and systemic lupus erythematosus. | BMC medical genetics 20110101 |
Evolution of acetylcholinesterase and butyrylcholinesterase in the vertebrates: an atypical butyrylcholinesterase from the Medaka Oryzias latipes. | PloS one 20110101 |
Consistency of the disposition index in the face of diet induced insulin resistance: potential role of FFA. | PloS one 20110101 |
Immobilization of organophosphate hydrolase on an amyloid fibril nanoscaffold: towards bioremediation and chemical detoxification. | Biotechnology progress 20110101 |
Simultaneous determination of a novel antitrypanosomal compound (OSU-36) and its ester derivative (OSU-40) in plasma by HPLC: application to first pharmacokinetic study in rats. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20110101 |
Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles. | Biotechnology progress 20110101 |
Paraoxonase 1 polymorphism Q192R affects the pro-inflammatory cytokine TNF-alpha in healthy males. | BMC research notes 20110101 |
Paraoxonase 1 (PON1) polymorphisms, haplotypes and activity in predicting cad risk in North-West Indian Punjabis. | PloS one 20110101 |
A conjugate of pyridine-4-aldoxime and atropine as a potential antidote against organophosphorus compounds poisoning. | Acta biochimica Polonica 20110101 |
In vitro ability of currently available oximes to reactivate organophosphate pesticide-inhibited human acetylcholinesterase and butyrylcholinesterase. | International journal of molecular sciences 20110101 |
Assessment of acetylcholinesterase activity using indoxylacetate and comparison with the standard Ellman's method. | International journal of molecular sciences 20110101 |
Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation. | Vascular health and risk management 20110101 |
Serum paraoxonase 1 activity predicts arterial stiffness in renal transplant recipients. | Journal of atherosclerosis and thrombosis 20110101 |
Single-step production of a recyclable nanobiocatalyst for organophosphate pesticides biodegradation using functionalized bacterial magnetosomes. | PloS one 20110101 |
Effects of paraoxon on neuronal and lymphocytic cholinergic systems. | Environmental toxicology and pharmacology 20110101 |
Effect of coenzyme Q10 on ischemia and neuronal damage in an experimental traumatic brain-injury model in rats. | BMC neuroscience 20110101 |
Biochemical study of oxidative stress markers in the liver, kidney and heart of high fat diet induced obesity in rats. | Diabetology & metabolic syndrome 20110101 |
Estimation of enzyme kinetic parameters of cell surface-displayed organophosphorus hydrolase and construction of a biosensing system for organophosphorus compounds. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101 |
Non-invasive markers for hepatic fibrosis. | BMC gastroenterology 20110101 |
Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis. | Frontiers in pharmacology 20110101 |
Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women. | PloS one 20110101 |
Homology modeling of human serum paraoxonase1 and its molecular interaction studies with aspirin and cefazolin. | Bioinformation 20110101 |
Paraoxonase-1 (PON1) activity in patients with coronary artery diseases and in diabetic patients. | Annales de biologie clinique 20110101 |
A label-free electrochemical immunosensor for carbofuran detection based on a sol-gel entrapped antibody. | Sensors (Basel, Switzerland) 20110101 |
Effects of sublethal exposure of European brown hares to paraoxon on the course of tularemia. | Neuro endocrinology letters 20110101 |
Luminescence sensors applied to water analysis of organic pollutants--an update. | Sensors (Basel, Switzerland) 20110101 |
Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2. | Chemical research in toxicology 20101220 |
Down-regulated transcriptional level of Ace1 combined with mutations in Ace1 and Ace2 of Aphis gossypii are related with omethoate resistance. | Chemico-biological interactions 20101205 |
Purification and properties of digestive lipases from Chinook salmon (Oncorhynchus tshawytscha) and New Zealand hoki (Macruronus novaezelandiae). | Fish physiology and biochemistry 20101201 |
Improving the promiscuous nerve agent hydrolase activity of a thermostable archaeal lactonase. | Bioresource technology 20101201 |
Functional analysis and molecular characterization of two acetylcholinesterases from the German cockroach, Blattella germanica. | Insect molecular biology 20101201 |
Effects of atropine and pralidoxime on neuronal actions of paraoxon in rat hippocampal slices. | Neuroscience research 20101201 |
PON1 and neurodevelopment in children from the CHAMACOS study exposed to organophosphate pesticides in utero. | Environmental health perspectives 20101201 |
Cholinergic crisis after rodenticide poisoning. | The western journal of emergency medicine 20101201 |
Paraoxon-induced protein expression changes to SH-SY5Y cells. | Chemical research in toxicology 20101115 |
Paraoxonase-1 activity determination via paraoxon substrate yields no significant difference in mild hyperhomocysteinemia. | International journal of cardiology 20101105 |
Paraoxon, 4-nitrophenyl phosphate and acetate are substrates of α- but not of β-, γ- and ζ-carbonic anhydrases. | Bioorganic & medicinal chemistry letters 20101101 |
Hydrolysis of p-nitrophenyl esters promoted by semifluorinated quaternary ammonium polymer latexes and films. | Langmuir : the ACS journal of surfaces and colloids 20101019 |
Synthesis of cholesterol-conjugated magnetic nanoparticles for purification of human paraoxonase 1. | Applied biochemistry and biotechnology 20101001 |
Differential effects of some antibiotics on paraoxonase enzyme activity on human hepatoma cells (HepG2) in vitro. | Journal of enzyme inhibition and medicinal chemistry 20101001 |
Paraoxonase activity in athletes with depleted iron stores and iron-deficient erythropoiesis. | Clinical biochemistry 20101001 |
Diversity and impact of prokaryotic toxins on aquatic environments: a review. | Toxins 20101001 |
Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol. | Journal of controlled release : official journal of the Controlled Release Society 20100915 |
Lactonases with organophosphatase activity: structural and evolutionary perspectives. | Chemico-biological interactions 20100906 |
Synthesis and evaluation of novel analogues of vitamin B6 as reactivators of tabun and paraoxon inhibited acetylcholinesterase. | Chemico-biological interactions 20100906 |
Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae. | Chemico-biological interactions 20100906 |
Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase. | Chemico-biological interactions 20100906 |
Serum albumins and detoxication of anti-cholinesterase agents. | Chemico-biological interactions 20100906 |
Novel oximes as blood-brain barrier penetrating cholinesterase reactivators. | Chemico-biological interactions 20100906 |
Investigating the structural influence of surface mutations on acetylcholinesterase inhibition by organophosphorus compounds and oxime reactivation. | Chemico-biological interactions 20100906 |
Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase. | Chemico-biological interactions 20100906 |
Antioxidant potential, paraoxonase 1, ceruloplasmin activity and C-reactive protein concentration in diabetic retinopathy. | Clinical and experimental medicine 20100901 |
Association of midgestation paraoxonase 1 activity and pregnancies complicated by preterm birth. | American journal of obstetrics and gynecology 20100901 |
Constitutive androstane receptor -null mice are sensitive to the toxic effects of parathion: association with reduced cytochrome p450-mediated parathion metabolism [corrected]. | Drug metabolism and disposition: the biological fate of chemicals 20100901 |
Paraoxonase 1 activity as a predictor of cardiovascular disease in type 2 diabetes. | The Southeast Asian journal of tropical medicine and public health 20100901 |
Baculovirus expression, biochemical characterization and organophosphate sensitivity of rBmAChE1, rBmAChE2, and rBmAChE3 of Rhipicephalus (Boophilus) microplus. | Veterinary parasitology 20100827 |
Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase. | Journal of enzyme inhibition and medicinal chemistry 20100801 |
Pharmacokinetics and toxicodynamics of pralidoxime effects on paraoxon-induced respiratory toxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20100801 |
Bioactive paper dipstick sensors for acetylcholinesterase inhibitors based on sol-gel/enzyme/gold nanoparticle composites. | The Analyst 20100801 |
Thionate versus Oxon: comparison of stability, uptake, and cell toxicity of ((14)CH(3)O)(2)-labeled methyl parathion and methyl paraoxon with SH-SY5Y cells. | Journal of agricultural and food chemistry 20100728 |
The differentiating effect of glimepiride and glibenclamide on paraoxonase 1 and platelet-activating factor acetylohydrolase activity. | Life sciences 20100717 |
X-ray crystallographic and MD simulation studies on the mechanism of interfacial activation of a family I.3 lipase with two lids. | Journal of molecular biology 20100702 |
Cholinergic stimulation of the immune system protects against lethal infection by Salmonella enterica serovar Typhimurium. | Immunology 20100701 |
Disposable electrochemical printed gold chips for the analysis of acetylcholinesterase inhibition. | Analytica chimica acta 20100611 |
Muscle force and acetylcholinesterase activity in mouse hemidiaphragms exposed to paraoxon and treated by oximes in vitro. | Toxicology 20100604 |
Mechanisms of insulin resistance after insulin-induced hypoglycemia in humans: the role of lipolysis. | Diabetes 20100601 |
Critical role of the mesenteric depot versus other intra-abdominal adipose depots in the development of insulin resistance in young rats. | Diabetes 20100601 |
Sonolytic degradation of parathion and the formation of byproducts. | Ultrasonics sonochemistry 20100601 |
Comparative modeling of PON2 and analysis of its substrate binding interactions using computational methods. | Journal of ocular biology, diseases, and informatics 20100601 |
Solution chemistry of self-assembled graphene nanohybrids for high-performance flexible biosensors. | ACS nano 20100525 |
Multi-enzyme inhibition assay for the detection of insecticidal organophosphates and carbamates by high-performance thin-layer chromatography applied to determine enzyme inhibition factors and residues in juice and water samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100515 |
Comparative study of oxime-induced reactivation of erythrocyte and muscle AChE from different animal species following inhibition by sarin or paraoxon. | Toxicology letters 20100504 |
Improvement in organophosphorus hydrolase activity of cell surface-engineered yeast strain using Flo1p anchor system. | Biotechnology letters 20100501 |
Enhanced stability of enzyme organophosphate hydrolase interfaced on the carbon nanotubes. | Colloids and surfaces. B, Biointerfaces 20100501 |
Organophosphorus compound detection on a cell chip with yeast coexpressing hydrolase and eGFP. | Biotechnology journal 20100501 |
Cloning and characterization of acetylcholinesterase 1 genes from insecticide-resistant field populations of Liposcelis paeta Pearman (Psocoptera: Liposcelididae). | Insect biochemistry and molecular biology 20100501 |
Development of Au nanoparticles dispersed carbon nanotube-based biosensor for the detection of paraoxon. | Nanoscale 20100501 |
Colorimetric dipstick for assay of organophosphate pesticides and nerve agents represented by paraoxon, sarin and VX. | Talanta 20100415 |
Calcium signals and caspase-12 participated in paraoxon-induced apoptosis in EL4 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20100401 |
An alternative in vitro method for detecting neuropathic compounds based on acetylcholinesterase inhibition and on inhibition and aging of neuropathy target esterase (NTE). | Toxicology in vitro : an international journal published in association with BIBRA 20100401 |
Central cholinesterase inhibition enhances glutamatergic synaptic transmission. | Journal of neurophysiology 20100401 |
Serum paraoxonase 1 activity status in patients with liver disorders. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20100401 |
Carbon nanotube-polymer based nanocomposite as electrode material for the detection of paraoxon. | Journal of nanoscience and nanotechnology 20100401 |
Biomagnetic glasses: preparation, characterization, and biosensor applications. | Langmuir : the ACS journal of surfaces and colloids 20100316 |
Mechanism and kinetics of parathion degradation under ultrasonic irradiation. | Journal of hazardous materials 20100315 |
Association of midgestational paraoxonase 1 activity with pregnancies complicated by preeclampsia. | American journal of perinatology 20100301 |
Diet-induced obesity prevents interstitial dispersion of insulin in skeletal muscle. | Diabetes 20100301 |
Biochemical, metabolic, and behavioural responses and recovery of Daphnia magna after exposure to an organophosphate. | Ecotoxicology and environmental safety 20100301 |
Influence of oryzanol and ferulic Acid on the lipid metabolism and antioxidative status in high fat-fed mice. | Journal of clinical biochemistry and nutrition 20100301 |
Total oxidant status, total antioxidant status, and paraoxonase and arylesterase activities during laparoscopic cholecystectomy. | Clinics (Sao Paulo, Brazil) 20100301 |
Investigation of in vitro effects of ethephon and chlorpyrifos, either alone or in combination, on rat intestinal muscle contraction. | Interdisciplinary toxicology 20100301 |
AChE biosensor based on zinc oxide sol-gel for the detection of pesticides. | Analytica chimica acta 20100227 |
Acetylcholinesterase point mutations in European strains of Tetranychus urticae (Acari: Tetranychidae) resistant to organophosphates. | Pest management science 20100201 |
Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates. | Bioorganic & medicinal chemistry letters 20100201 |
Monooxime-monocarbamoyl Bispyridinium Xylene-Linked Reactivators of Acetylcholinesterase-Synthesis, In vitro and Toxicity Evaluation, and Docking Studies. | ChemMedChem 20100201 |
Evaluation of serum paraoxonase and arylesterase activities in ankylosing spondylitis patients. | Clinics (Sao Paulo, Brazil) 20100201 |
Effect of quercetin on paraoxonase 1 activity--studies in cultured cells, mice and humans. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100201 |
Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. | Bioorganic & medicinal chemistry 20100115 |
Nanogravimetric and voltammetric DNA-hybridization biosensors for studies of DNA damage by common toxicants and pollutants. | Biophysical chemistry 20100101 |
In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene. | BMC systems biology 20100101 |
Heterologous expression, purification, and biochemical characterization of a greenbug (Schizaphis graminum) acetylcholinesterase encoded by a paralogous gene (ace-1). | Journal of biochemical and molecular toxicology 20100101 |
Adsorption of obidoxime onto human serum albumin nanoparticles: drug loading, particle size and drug release. | Journal of microencapsulation 20100101 |
Paraoxonase 1 status as a risk factor for disease or exposure. | Advances in experimental medicine and biology 20100101 |
The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status. | Advances in experimental medicine and biology 20100101 |
Methodological constraints in interpreting serum paraoxonase-1 activity measurements: an example from a study in HIV-infected patients. | Lipids in health and disease 20100101 |
Cannabinoid receptor agonist WIN-55,212-2 protects differentiated PC12 cells from organophosphorus- induced apoptosis. | International journal of toxicology 20100101 |
Paraoxon attenuates vascular smooth muscle contraction through inhibiting Ca2+ influx in the rabbit thoracic aorta. | Journal of biomedicine & biotechnology 20100101 |
Diet and paraoxonase 1 enzymatic activity in diabetic foot patients from Romania and Belgium: favorable association of high flavonoid dietary intake with arylesterase activity. | Annals of nutrition & metabolism 20100101 |
Decreased paraoxonase-1 activity is associated with alterations of high-density lipoprotein particles in chronic liver impairment. | Lipids in health and disease 20100101 |
Organophosphorus pesticides decrease M2 muscarinic receptor function in guinea pig airway nerves via indirect mechanisms. | PloS one 20100101 |
Paraoxonase: Its antiatherogenic role in chronic renal failure. | Indian journal of nephrology 20100101 |
Bionanoconjugate-based composites for decontamination of nerve agents. | Biotechnology progress 20100101 |
Effect of HDL composition and particle size on the resistance of HDL to the oxidation. | Lipids in health and disease 20100101 |
Incorporation of obidoxime into human serum albumin nanoparticles: optimisation of preparation parameters for the development of a stable formulation. | Journal of microencapsulation 20100101 |
[Echinocytosis and changes of medium weight molecules content in endo- and exogenous intoxications]. | Morfologiia (Saint Petersburg, Russia) 20100101 |
Lower paraoxonase 1 activity in Tunisian bipolar I patients. | Annals of general psychiatry 20100101 |
Reactivation of human acetylcholinesterase and butyrylcholinesterase inhibited by leptophos-oxon with different oxime reactivators in vitro. | International journal of molecular sciences 20100101 |
Pralidoxime--the gold standard of acetylcholinesterase reactivators--reactivation in vitro efficacy. | Bratislavske lekarske listy 20100101 |
A high-throughput enzyme assay for organophosphate residues in milk. | Sensors (Basel, Switzerland) 20100101 |
Fluorescent chemosensors for toxic organophosphorus pesticides: a review. | Sensors (Basel, Switzerland) 20100101 |
Recent trends in monitoring of European water framework directive priority substances using micro-sensors: a 2007-2009 review. | Sensors (Basel, Switzerland) 20100101 |
Study of a QCM dimethyl methylphosphonate sensor based on a ZnO-modified nanowire-structured manganese dioxide film. | Sensors (Basel, Switzerland) 20100101 |
Direct electrochemistry and electrocatalysis of hemoglobin at mesoporous carbon modified electrode. | Sensors (Basel, Switzerland) 20100101 |
Fluorescent silicate materials for the detection of paraoxon. | Sensors (Basel, Switzerland) 20100101 |
ISFET based microsensors for environmental monitoring. | Sensors (Basel, Switzerland) 20100101 |
Sonochemically fabricated microelectrode arrays for use as sensing platforms. | Sensors (Basel, Switzerland) 20100101 |
A common mutation in paraoxonase-2 results in impaired lactonase activity. | The Journal of biological chemistry 20091218 |
The role of paraoxonase polymorphisms in the induction of micronucleus in paraoxon-treated human lymphocytes. | Environmental and molecular mutagenesis 20091201 |
Es-x/Ces1 prevents triacylglycerol accumulation in McArdle-RH7777 hepatocytes. | Biochimica et biophysica acta 20091201 |
Novel bisquaternary oximes--reactivation of acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon. | Molecules (Basel, Switzerland) 20091201 |
Molecular dynamics simulations of the detoxification of paraoxon catalyzed by phosphotriesterase. | Journal of computational chemistry 20091130 |
Combining medium effects and cofactor catalysis: metal-coordinated synzymes accelerate phosphate transfer by 10(8). | Chemistry (Weinheim an der Bergstrasse, Germany) 20091116 |
Biomonitoring of organophosphorus agent exposure by reactivation of cholinesterase enzyme based on carbon nanotube-enhanced flow-injection amperometric detection. | Analytical chemistry 20091115 |
Dramatic differences in organophosphorus hydrolase activity between human and chimeric recombinant mammalian paraoxonase-1 enzymes. | Biochemistry 20091103 |
Carboxylesterase activity in earthworm gut contents: Potential (eco)toxicological implications. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20091101 |
Relations of lysophosphatidylcholine in low-density lipoprotein with serum lipoprotein-associated phospholipase A2, paraoxonase and homocysteine thiolactonase activities in patients with type 2 diabetes mellitus. | Diabetes research and clinical practice 20091101 |
Reagentless bidirectional lateral flow bioactive paper sensors for detection of pesticides in beverage and food samples. | Analytical chemistry 20091101 |
Changes on the physiological lactonase activity of serum paraoxonase 1 by a diet intervention for weight loss in healthy overweight and obese women. | Journal of clinical biochemistry and nutrition 20091101 |
Genotyping mutations in BmAChE3: A survey of organophosphate-resistant and -susceptible strains of Rhipicephalus (Boophilus) microplus. | Journal of medical entomology 20091101 |
Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. | Journal of molecular biology 20091016 |
Lysozyme-mediated formation of protein-silica nano-composites for biosensing applications. | Colloids and surfaces. B, Biointerfaces 20091001 |
Relationships between paraoxon and 2-coumaranone hydrolytic activities in sera genotyped for PON1 Q192R polymorphism. | Clinical biochemistry 20091001 |
Study of acetylcholinesterase inhibitors using CE with contactless conductivity detection. | Electrophoresis 20091001 |
192R allele of paraoxanase 1 (PON1) gene as a new marker for susceptibility to bladder cancer. | Anticancer research 20091001 |
Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphisms. | Environmental health perspectives 20091001 |
Comparing the inhibitory effects of five protoxicant organophosphates (azinphos-methyl, parathion-methyl, chlorpyriphos-methyl, methamidophos and diazinon) on the spontaneously beating auricle of Sparus aurata: an in vitro study. | Aquatic toxicology (Amsterdam, Netherlands) 20090914 |
Extreme variability in the formation of chlorpyrifos oxon (CPO) in patients poisoned by chlorpyrifos (CPF). | Biochemical pharmacology 20090901 |
Development of square wave voltammetry method for the assessment of organophosphorus compound impact on the cholinesterase of Pheretima with 2,6-dichloroindophenol as a redox indicator. | Chemosphere 20090901 |
Recombinant expression and biochemical characterization of the catalytic domain of acetylcholinesterase-1 from the African malaria mosquito, Anopheles gambiae. | Insect biochemistry and molecular biology 20090901 |
New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. | Bioorganic & medicinal chemistry letters 20090901 |
Fluorinated pyridinium oximes as potential reactivators for acetylcholinesterases inhibited by paraoxon organophosphorus agent. | Bioorganic & medicinal chemistry 20090901 |
Structure of EstA esterase from psychrotrophic Pseudoalteromonas sp. 643A covalently inhibited by monoethylphosphonate. | Acta crystallographica. Section F, Structural biology and crystallization communications 20090901 |
The Pine River statement: human health consequences of DDT use. | Environmental health perspectives 20090901 |
Development of MWNT based disposable biosensor on glassy carbon electrode for the detection of organophosphorus nerve agents. | Journal of nanoscience and nanotechnology 20090901 |
Acute renal failure enhances the antidotal activity of pralidoxime towards paraoxon-induced respiratory toxicity. | Toxicology letters 20090825 |
Orientation specific positioning of organophosphorus hydrolase on solid interfaces for biosensor applications. | Langmuir : the ACS journal of surfaces and colloids 20090818 |
In vitro assessment of paraoxon effects on GABA uptake in rat hippocampal synaptosomes. | Toxicology in vitro : an international journal published in association with BIBRA 20090801 |
Organophosphorus pesticide ozonation and formation of oxon intermediates. | Chemosphere 20090801 |
Update on biochemical properties of recombinant Pseudomonas diminuta phosphotriesterase. | Journal of enzyme inhibition and medicinal chemistry 20090801 |
Minireview: does in-vitro testing of oximes help predict their in-vivo action after paraoxon exposure? | Journal of applied toxicology : JAT 20090801 |
Southern Discomfort?: PON1 variation may help explain regional CVD risk. | Environmental health perspectives 20090801 |
Racial differences in paraoxonase-1 (PON1): a factor in the health of southerners? | Environmental health perspectives 20090801 |
Relationship between human paraoxonase-1 activity and PON1 polymorphisms in Mexican workers exposed to organophosphate pesticides. | Toxicology letters 20090724 |
Simultaneous degradation of organophosphates and 4-substituted phenols by Stenotrophomonas species LZ-1 with surface-displayed organophosphorus hydrolase. | Journal of agricultural and food chemistry 20090722 |
Interaction between human serum esterases and environmental metal compounds. | Neurotoxicology 20090701 |
Development of a bioactive paper sensor for detection of neurotoxins using piezoelectric inkjet printing of sol-gel-derived bioinks. | Analytical chemistry 20090701 |
Efficacy of eight experimental bispyridinium oximes against paraoxon-induced mortality: comparison with the conventional oximes pralidoxime and obidoxime. | Neurotoxicity research 20090701 |
Carboxylic ester hydrolases from hyperthermophiles. | Extremophiles : life under extreme conditions 20090701 |
In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase. | Clinical toxicology (Philadelphia, Pa.) 20090701 |
A novel process for the fabrication of nanocomposites membranes. | Journal of nanoscience and nanotechnology 20090701 |
Microcalorimetric study of the inhibition of butyrylcholinesterase by paraoxon. | Analytical biochemistry 20090615 |
Exploration of the susceptibility of AChE from the poultry red mite Dermanyssus gallinae (Acari: Mesostigmata) to organophosphates in field isolates from France. | Experimental & applied acarology 20090601 |
Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090601 |
Cholinesterase based amperometric biosensors for assay of anticholinergic compounds. | Interdisciplinary toxicology 20090601 |
Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis. | Toxicology 20090517 |
A study of the degradation of organophosphorus pesticides in river waters and the identification of their degradation products by chromatography coupled with mass spectrometry. | Archives of environmental contamination and toxicology 20090501 |
In silico analyses of substrate interactions with human serum paraoxonase 1. | Proteins 20090501 |
Cholinesterase inhibition and acetylcholine accumulation following intracerebral administration of paraoxon in rats. | Toxicology and applied pharmacology 20090501 |
Measurement of serum paraoxonase-1 activity in the evaluation of liver function. | World journal of gastroenterology 20090428 |
Comparison of the oxime-induced reactivation of rhesus monkey, swine and guinea pig erythrocyte acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity. | Toxicology 20090428 |
Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin. | Biochemistry 20090421 |
Choline oxidase as a selective recognition element for determination of paraoxon. | Biosensors & bioelectronics 20090415 |
Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds. | Toxicology and applied pharmacology 20090415 |
Hydrolysis of p-nitrophenyl esters in mixtures of water and a fluorous solvent. | Langmuir : the ACS journal of surfaces and colloids 20090409 |
Silica-bound copper(II)triazacyclononane as a phosphate esterase: effect of linker length and surface hydrophobicity. | Dalton transactions (Cambridge, England : 2003) 20090407 |
Covalent immobilization of Drosophila acetylcholinesterase for biosensor applications. | Biotechnology and applied biochemistry 20090401 |
The use of Fluoro-Jade in primary neuronal cell cultures. | Archives of toxicology 20090401 |
Toxicological assessment of chemicals using Caenorhabditis elegans and optical oxygen respirometry. | Environmental toxicology and chemistry 20090401 |
Validation of PON1 enzyme activity assays for longitudinal studies. | Clinica chimica acta; international journal of clinical chemistry 20090401 |
Toxicodynamic analysis of the combined cholinesterase inhibition by paraoxon and methamidophos in human whole blood. | Toxicology and applied pharmacology 20090401 |
Catalytic bioscavengers against toxic esters, an alternative approach for prophylaxis and treatments of poisonings. | Acta naturae 20090401 |
Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily. | Biochemistry 20090317 |
Effects of micelles and vesicles on the oximolysis of p-nitrophenyl diphenyl phosphate: A model system for surfactant-based skin-defensive formulations against organophosphates. | Journal of pharmaceutical sciences 20090301 |
Paraoxonase 1 activity in different types of multiple sclerosis. | Multiple sclerosis (Houndmills, Basingstoke, England) 20090301 |
Serum paraoxonase-I activity is unaffected by short-term administration of simvastatin, bezafibrate, and their combination in type 2 diabetes mellitus. | European journal of clinical investigation 20090301 |
Type of cell death and the role of acetylcholinesterase activity in neurotoxicity induced by paraoxon in cultured rat hippocampal neurons. | Acta biologica Hungarica 20090301 |
Mitochondrial ATP synthase inhibition and nitric oxide are involved in muscle weakness that occurs in acute exposure of rats to monocrotophos. | Toxicology mechanisms and methods 20090301 |
Paraoxonase 1 (PON1) status and substrate hydrolysis. | Toxicology and applied pharmacology 20090215 |
Reactivation potency of fluorinated pyridinium oximes for acetylcholinesterases inhibited by paraoxon organophosphorus agent. | Bioorganic & medicinal chemistry letters 20090215 |
Evaluation of in vitro tests to assess the efficacy of formulations as topical skin protectants against organophosphorus compounds. | Toxicology in vitro : an international journal published in association with BIBRA 20090201 |
Determinants of variation in human serum paraoxonase activity. | Heredity 20090201 |
Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain. | Journal of molecular biology 20090123 |
Purification human PON1Q192 and PON1R192 isoenzymes by hydrophobic interaction chromatography and investigation of the inhibition by metals. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115 |
Automated resolution of dichlorvos and methylparaoxon pesticide mixtures employing a Flow Injection system with an inhibition electronic tongue. | Biosensors & bioelectronics 20090101 |
The measurement of the lactonase activity of paraoxonase-1 in the clinical evaluation of patients with chronic liver impairment. | Clinical biochemistry 20090101 |
Modulated growth of nanoparticles. Application for sensing nerve gases. | Analytical chemistry 20090101 |
Paraoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease. | BMC gastroenterology 20090101 |
A set of piezoelectric biosensors using cholinesterases. | Methods in molecular biology (Clifton, N.J.) 20090101 |
Clinical outcomes and kinetics of propanil following acute self-poisoning: a prospective case series. | BMC clinical pharmacology 20090101 |
Physicochemical characterization of stealth liposomes encapsulating an organophosphate hydrolyzing enzyme. | Journal of liposome research 20090101 |
Effect of inhibition of neuropathy target esterase in mouse nervous tissues in vitro on phosphatidylcholine and lysophosphatidylcholine homeostasis. | International journal of toxicology 20090101 |
Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study. | PloS one 20090101 |
Development of an indirect enzyme-linked immunosorbent assay for the organophosphorus pesticide paraoxon-methyl. | Immunological investigations 20090101 |
Effect of atorvastatin on paraoxonase1 (PON1) and oxidative status. | Pharmacological reports : PR 20090101 |
In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes. | BMC clinical pharmacology 20090101 |
Annotation and expression of carboxylesterases in the silkworm, Bombyx mori. | BMC genomics 20090101 |
Studies on HDL associated enzymes under experimental hypercholesterolemia: possible modulation on selenium supplementation. | Lipids in health and disease 20090101 |
Genetic polymorphism in paraoxonase 1 (PON1): Population distribution of PON1 activity. | Journal of toxicology and environmental health. Part B, Critical reviews 20090101 |
Variation of cholinesterase-based biosensor sensitivity to inhibition by organophosphate due to ionizing radiation. | Sensors (Basel, Switzerland) 20090101 |
Recent advances in nanotechnology applied to biosensors. | Sensors (Basel, Switzerland) 20090101 |
Nanomaterials - acetylcholinesterase enzyme matrices for organophosphorus pesticides electrochemical sensors: a review. | Sensors (Basel, Switzerland) 20090101 |
Evaluation of cholinesterase activities during in vivo intoxication using an electrochemical sensor strip - correlation with intoxication symptoms. | Sensors (Basel, Switzerland) 20090101 |
Semiconductor quantum dots in chemical sensors and biosensors. | Sensors (Basel, Switzerland) 20090101 |
Photometric microplate assay for estimation of the efficacy of paraoxon-inhibited acetylcholinesterase reactivation. | Journal of enzyme inhibition and medicinal chemistry 20081201 |
Ventilatory effects of low-dose paraoxon result from central muscarinic effects. | Toxicology and applied pharmacology 20081201 |
Degradation and byproduct formation of parathion in aqueous solutions by UV and UV/H(2)O(2) treatment. | Water research 20081201 |
Oligopeptides as mimic of acetylcholinesterase: from the rational design to the application in solid-phase extraction for pesticides. | Analytical chemistry 20081201 |
Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. | Bioorganic & medicinal chemistry letters 20081115 |
Magnetic electrochemical immunoassays with quantum dot labels for detection of phosphorylated acetylcholinesterase in plasma. | Analytical chemistry 20081115 |
Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis. | The Journal of biological chemistry 20081114 |
Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology. | Toxicological sciences : an official journal of the Society of Toxicology 20081101 |
The influence of the support nature on the kinetics parameters, inhibition constants and reactivation of immobilized acetylcholinesterase. | International journal of biological macromolecules 20081101 |
Hypotension in severe dimethoate self-poisoning. | Clinical toxicology (Philadelphia, Pa.) 20081101 |
Improvement of acetylcholinesterase-based assay for organophosphates in way of identification by reactivators. | Talanta 20081019 |
A fully validated isotope dilution HPLC-MS/MS method for the simultaneous determination of succinylcholine and succinylmonocholine in serum and urine samples. | Journal of mass spectrometry : JMS 20081001 |
Induction of paraoxonase 1 and apolipoprotein A-I gene expression by aspirin. | Journal of lipid research 20081001 |
PON1Q192R polymorphism is associated with lipid profile in Mexican men with Mayan ascendancy. | Experimental and molecular pathology 20081001 |
Acetylcholinesterase-based biosensors for quantification of carbofuran, carbaryl, methylparaoxon, and dichlorvos in 5% acetonitrile. | Analytical and bioanalytical chemistry 20081001 |
Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages. | Biochimica et biophysica acta 20081001 |
Increased organophosphate scavenging in a butyrylcholinesterase mutant. | Chemico-biological interactions 20080925 |
Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes. | Chemico-biological interactions 20080925 |
Reactivation of model cholinesterases by oximes and intermediate phosphyloximes: a computational study. | Chemico-biological interactions 20080925 |
Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro. | Chemico-biological interactions 20080925 |
Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin. | Chemical research in toxicology 20080915 |
Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation. | Biochemistry 20080909 |
Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase. | Biochemistry 20080909 |
Irreversible inhibition of the thermophilic esterase EST2 from Alicyclobacillus acidocaldarius. | Extremophiles : life under extreme conditions 20080901 |
PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients. | Clinical biochemistry 20080901 |
Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase. | Bioorganic & medicinal chemistry 20080901 |
Glycation of paraoxonase-1 inhibits its activity and impairs the ability of high-density lipoprotein to metabolize membrane lipid hydroperoxides. | Diabetic medicine : a journal of the British Diabetic Association 20080901 |
Acute fatal presentation of ornithine transcarbamylase deficiency in a previously healthy male. | Hepatology international 20080901 |
Protective effects of mecamylamine and atropine against α(4)β(2) nicotinic receptor expression and functional toxicity in paraoxon-treated rats. | Environmental toxicology and pharmacology 20080901 |
Gas-phase mechanisms of degradation of hazardous organophosphorus compounds: do they follow a common pattern of alkaline hydrolysis reaction as in phosphotriesterase? | The journal of physical chemistry. B 20080814 |
Association between p.Leu54Met polymorphism at the paraoxonase-1 gene and plantar fascia thickness in young subjects with type 1 diabetes. | Diabetes care 20080801 |
Serum albumin is as efficient as paraxonase in the detoxication of paraoxon at toxicologically relevant concentrations. | Chemical research in toxicology 20080801 |
Interethnic variability of plasma paraoxonase (PON1) activity towards organophosphates and PON1 polymorphisms among Asian populations--a short review. | Industrial health 20080801 |
Oxydemeton-methyl resistance, mechanisms, and associated fitness cost in green peach aphids (Hemiptera: Aphididae). | Journal of economic entomology 20080801 |
Gastrointestinal nematode infection increases organophosphate toxicity in rats. | Toxicology letters 20080730 |
PON1Q192R genetic polymorphism modifies organophosphorous pesticide effects on semen quality and DNA integrity in agricultural workers from southern Mexico. | Toxicology and applied pharmacology 20080715 |
Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex. | Journal of lipid research 20080701 |
Effect of intrathecal pralidoxime administration upon survival of rats exposed to the organophosphate paraoxon. | Neurotoxicology 20080701 |
The spectrum of intermediate syndrome following acute organophosphate poisoning: a prospective cohort study from Sri Lanka. | PLoS medicine 20080701 |
Evaluation of nicotinic receptors agonists and antagonists against paraoxon exposed PC12 cells. | Environmental toxicology and pharmacology 20080701 |
Engineered bacterial outer membrane vesicles with enhanced functionality. | Journal of molecular biology 20080627 |
Activation of the endocannabinoid system by organophosphorus nerve agents. | Nature chemical biology 20080601 |
Biodegradation of organophosphate pesticide using recombinant Cyanobacteria with surface- and intracellular-expressed organophosphorus hydrolase. | Journal of microbiology and biotechnology 20080501 |
Simple procedures for purification and stabilization of human serum paraoxonase-1. | Journal of biochemical and biophysical methods 20080424 |
Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors. | Toxicology 20080418 |
Simplified speciation and improved phosphodiesterolytic activity of hydroxo complexes of trivalent lanthanides in aqueous DMSO. | Inorganic chemistry 20080407 |
Percutaneous penetration and distribution of VX using in vitro pig or human excised skin validation of demeton-S-methyl as adequate simulant for VX skin permeation investigations. | Toxicology 20080403 |
[Preparation and characterization of parathion sensor based on molecularly imprinted polymer]. | Huan jing ke xue= Huanjing kexue 20080401 |
Association of paraoxonase activity and coronary blood flow. | Atherosclerosis 20080301 |
Management of acute organophosphorus pesticide poisoning. | Lancet (London, England) 20080216 |
Determination of active enzyme concentration using activity-based probes and direct mass spectrometric readout. | Analytical biochemistry 20080215 |
Inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds: pig versus minipig acetylcholinesterase. | Toxicology 20080203 |
Synaptosomal GABA uptake decreases in paraoxon-treated rat brain. | Toxicology 20080203 |
Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity. | Biochemical pharmacology 20080201 |
Lipotoxic effects of triacylglycerols in J774.2 macrophages. | Nutrition (Burbank, Los Angeles County, Calif.) 20080201 |
Alkali metal ion catalysis and inhibition in nucleophilic displacement reactions at phosphorus centers: ethyl and methyl paraoxon and ethyl and methyl parathion. | The Journal of organic chemistry 20080201 |
Alterations of the acetylcholinesterase enzyme in the oriental fruit fly Bactrocera dorsalis are correlated with resistance to the organophosphate insecticide fenitrothion. | Insect biochemistry and molecular biology 20080201 |
Paraoxonase 1 phenotype distribution and activity differs in subjects with newly diagnosed Type 2 diabetes (the CODAM Study). | Diabetic medicine : a journal of the British Diabetic Association 20080201 |
Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase. | Journal of enzyme inhibition and medicinal chemistry 20080201 |
The organophosphate-induced acute-phase response is characterized by synthesis of alpha 1-acid glycoprotein that exhibits an immunomodulatory effect. | Journal of applied toxicology : JAT 20080101 |
Genetic variation in the paraoxonase-3 (PON3) gene is associated with serum PON1 activity. | Annals of human genetics 20080101 |
High-density lipoprotein cholesterol and paraoxonase 1 (PON1) genetics and serum PON1 activity in prepubertal children in Spain. | Clinical chemistry and laboratory medicine 20080101 |
Nanoparticle-based electrochemical immunosensor for the detection of phosphorylated acetylcholinesterase: an exposure biomarker of organophosphate pesticides and nerve agents. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
Potential developmental neurotoxicity of pesticides used in Europe. | Environmental health : a global access science source 20080101 |
Reflectometric cutinase assay for rapid screening of contaminants and residues of insecticidal organophosphates and carbamates. | Journal of AOAC International 20080101 |
Paraoxonases (PON1, PON2, PON3) analyses in vitro and in vivo in relation to cardiovascular diseases. | Methods in molecular biology (Clifton, N.J.) 20080101 |
Hairy-root organ cultures for the production of human acetylcholinesterase. | BMC biotechnology 20080101 |
The organophosphate paraoxon has no demonstrable effect on the murine immune system following subchronic low dose exposure. | International journal of immunopathology and pharmacology 20080101 |
[Low paraoxonase and arylesterase plasma activities in Mexican patients with coronary artery disease]. | Archivos de cardiologia de Mexico 20080101 |
A high throughput serum paraoxonase assay for discovery of small molecule modulators of PON1 activity. | Current chemical genomics 20080101 |
Metabolism of ciclesonide in the upper and lower airways: review of available data. | Journal of asthma and allergy 20080101 |
Multienzyme inhibition assay for residue analysis of insecticidal organophosphates and carbamates. | Journal of agricultural and food chemistry 20071226 |
New oxime reactivators connected with CH2O(CH2)nOCH2 linker and their reactivation potency for organophosphorus agents-inhibited acetylcholinesterase. | Bioorganic & medicinal chemistry 20071215 |
Molecular cloning and expression of the C-terminal domain of mouse NTE-related esterase. | Molecular and cellular biochemistry 20071201 |
Paraoxon inhibits GABA uptake in brain synaptosomes. | Toxicology in vitro : an international journal published in association with BIBRA 20071201 |
Hydrolysis of a series of parabens by skin microsomes and cytosol from human and minipigs and in whole skin in short-term culture. | Toxicology and applied pharmacology 20071201 |
Photonic crystal sensor for organophosphate nerve agents utilizing the organophosphorus hydrolase enzyme. | Analytical and bioanalytical chemistry 20071201 |
The reaction mechanism of paraoxon hydrolysis by phosphotriesterase from combined QM/MM simulations. | Biochemistry 20071120 |
Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver. | Drug metabolism and disposition: the biological fate of chemicals 20071101 |
Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects. | Neurotoxicology 20071101 |
Forskolin potentiates the paraoxon-induced hyperexcitability in snail neurons by blocking afterhyperpolarization. | Neurotoxicology 20071101 |
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase. | Bioorganic & medicinal chemistry 20071101 |
R86Q, a mutation in BmAChE3 yielding a Rhipicephalus microplus organophosphate-insensitive acetylcholinesterase. | Journal of medical entomology 20071101 |
Biosensor system for continuous monitoring of organophosphate aerosols. | Biosensors & bioelectronics 20071031 |
Comparative hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate and paraoxon in different tissues of vertebrates. | Archives of toxicology 20071001 |
Involvement of protein kinase C and IP3-mediated Ca2+ release in activity modulation by paraoxon in snail neurons. | European journal of pharmacology 20071001 |
Effects of organophosphorus pesticides and their ozonation byproducts on gap junctional intercellular communication in rat liver cell line. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071001 |
Development of a yeast biosensor-biocatalyst for the detection and biodegradation of the organophosphate paraoxon. | Applied microbiology and biotechnology 20071001 |
Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901 |
High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism. | Clinical and experimental pharmacology & physiology 20070901 |
Metoclopramide protection of diazinon-induced toxicosis in chickens. | Journal of veterinary science 20070901 |
Association of oxidative stress and PON1 with LDL and HDL particle size in middle-aged subjects. | European journal of clinical investigation 20070901 |
The effect of paraoxon on GABA uptake in rat cerebellar synaptosomes. | Medical science monitor : international medical journal of experimental and clinical research 20070901 |
Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX. | Biochemistry 20070807 |
Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. | Journal of enzyme inhibition and medicinal chemistry 20070801 |
Decomposition reaction of organophosphorus nerve agents on solid surfaces with atmospheric radio frequency plasma generated gaseous species. | Langmuir : the ACS journal of surfaces and colloids 20070717 |
Fluorescence-based sensing of p-nitrophenol and p-nitrophenyl substituent organophosphates. | Analytica chimica acta 20070716 |
The role and characterization of phospholipase A1 in mediating lysophosphatidylcholine synthesis in Trypanosoma brucei. | The Biochemical journal 20070715 |
Enzyme-encapsulated silica monolayers for rapid functionalization of a gold surface. | Colloids and surfaces. B, Biointerfaces 20070701 |
Further biochemical characterization of human pancreatic lipase-related protein 2 expressed in yeast cells. | Journal of lipid research 20070701 |
Fast, sensitive and cost-effective detection of nerve agents in the gas phase using a portable instrument and an electrochemical biosensor. | Analytical and bioanalytical chemistry 20070701 |
Frequency of paraoxonase 192/55 polymorphism in an Iranian population. | Journal of toxicology and environmental health. Part A 20070701 |
Inhibition of protein kinase C protects against paraoxon-mediated neuronal cell death. | Neurotoxicology 20070701 |
Cholinesterase-based dipstick assay for the detection of organophosphate and carbamate pesticides. | Analytica chimica acta 20070626 |
Characterization of a novel cell wall-anchored protein with carboxylesterase activity required for virulence in Mycobacterium tuberculosis. | The Journal of biological chemistry 20070622 |
Pesticide detection with a liposome-based nano-biosensor. | Biosensors & bioelectronics 20070615 |
Array biosensor based on enzyme kinetics monitoring by fluorescence spectroscopy: application for neurotoxins detection. | Biosensors & bioelectronics 20070615 |
Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. | Bioorganic & medicinal chemistry letters 20070601 |
Effects of block length on the enzymatic degradation and erosion of oxazoline linked poly-epsilon-caprolactone. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070601 |
Assessment of paraoxonase activity and lipid peroxidation levels in diabetic and senile subjects suffering from cataract. | Clinical biochemistry 20070601 |
Concentration-dependent interactions of the organophosphates chlorpyrifos oxon and methyl paraoxon with human recombinant acetylcholinesterase. | Toxicology and applied pharmacology 20070601 |
Reduced paraoxonase1 activity is a risk for atherosclerosis in patients with systemic lupus erythematosus. | Annals of the New York Academy of Sciences 20070601 |
Organophosphorus hydrolase multilayer modified microcantilevers for organophosphorus detection. | Biosensors & bioelectronics 20070515 |
Brain acetylcholinesterase as a marine pesticide biomarker using Brazilian fishes. | Marine environmental research 20070501 |
A new phosphotriesterase from Sulfolobus acidocaldarius and its comparison with the homologue from Sulfolobus solfataricus. | Biochimie 20070501 |
Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults. | Toxicology 20070420 |
Testing of antidotes for organophosphorus compounds: experimental procedures and clinical reality. | Toxicology 20070420 |
Reversible inhibition of acetylcholinesterase by carbamates or huperzine A increases residual activity of the enzyme upon soman challenge. | Toxicology 20070420 |
Reevaluation of indirect field stimulation technique to demonstrate oxime effectiveness in OP-poisoning in muscles in vitro. | Toxicology 20070420 |
Effect of metal ions and calcium on purified PON1 and PON3 from rat liver. | Chemico-biological interactions 20070405 |
Aspirin is a substrate for paraoxonase-like activity: implications in atherosclerosis. | Atherosclerosis 20070401 |
Paradoxical effect of salbutamol in a model of acute organophosphates intoxication in guinea pigs: role of substance P release. | American journal of physiology. Lung cellular and molecular physiology 20070401 |
Efficacy of the bone injection gun in the treatment of organophosphate poisoning. | Biopharmaceutics & drug disposition 20070401 |
A wireless magnetoelastic biosensor for the direct detection of organophosphorus pesticides. | The Analyst 20070401 |
Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity. | Human & experimental toxicology 20070401 |
Toxic doses of paraoxon alter the respiratory pattern without causing respiratory failure in rats. | Toxicology 20070322 |
Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. | Journal of agricultural and food chemistry 20070321 |
Phospholipase B activity and organophosphorus compound toxicity in cultured neural cells. | Toxicology and applied pharmacology 20070301 |
Comparison of two pre-exposure treatment regimens in acute organophosphate (paraoxon) poisoning in rats: tiapride vs. pyridostigmine. | Toxicology and applied pharmacology 20070301 |
The search of the target of promotion: Phenylbenzoate esterase activities in hen peripheral nerve. | Toxicology and applied pharmacology 20070301 |
Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines. | Toxicology and applied pharmacology 20070301 |
Identification of a carboxylesterase expressed in protoplasts using fluorescence-activated cell sorting. | Plant biotechnology journal 20070301 |
Genetic and environmental determinants of the PON-1 phenotype. | European journal of clinical investigation 20070301 |
[Substituted cyclodextrins: an example of biomimetic catalyzers]. | Annales pharmaceutiques francaises 20070301 |
Effect of nonionic surfactants on Rhizopus homothallicus lipase activity: a comparative kinetic study. | Molecular biotechnology 20070301 |
High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon. | Biochemistry 20070220 |
Mutations of acetylcholinesterase1 contribute to prothiofos-resistance in Plutella xylostella (L.). | Biochemical and biophysical research communications 20070216 |
Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer. | Toxicology letters 20070205 |
Human hepatic cytochrome p450-specific metabolism of parathion and chlorpyrifos. | Drug metabolism and disposition: the biological fate of chemicals 20070201 |
The Relationship between PON1 phenotype and PON1-192 genotype in detoxification of three oxons by human liver. | Drug metabolism and disposition: the biological fate of chemicals 20070201 |
Accuracy and biological variation of human serum paraoxonase 1 activity and polymorphism (Q192R) by kinetic enzyme assay. | Clinical chemistry 20070201 |
Optical leaky waveguide biosensors for the detection of organophosphorus pesticides. | The Analyst 20070201 |
Early effects of neuropathy-inducing organophosphates on in vivo concentrations of three neurotrophins. | Neurotoxicity research 20070201 |
Effects of ischemia-reperfusion on the absorption and esterase metabolism of diltiazem in rat intestine. | Life sciences 20070109 |
Is paraoxonase 192 gene polymorphism a risk factor for membranoproliferative glomerulonephritis in children? | Cell biochemistry and function 20070101 |
Biosensing paraoxon in simulated environmental samples by immobilized organophosphorus hydrolase in functionalized mesoporous silica. | Journal of environmental quality 20070101 |
Paraoxon has only a minimal effect on pralidoxime brain concentration in rats. | Journal of applied toxicology : JAT 20070101 |
In vitro oxime reactivation of red blood cell acetylcholinesterase inhibited by methyl-paraoxon. | Journal of applied toxicology : JAT 20070101 |
Five oximes (K-27, K-48, obidoxime, HI-6 and trimedoxime) in comparison with pralidoxime: survival in rats exposed to methyl-paraoxon. | Journal of applied toxicology : JAT 20070101 |
Entry of two new asymmetric bispyridinium oximes (K-27 and K-48) into the rat brain: comparison with obidoxime. | Journal of applied toxicology : JAT 20070101 |
Serum paraoxonase and arylesterase activities in patients with lung cancer in a Turkish population. | BMC cancer 20070101 |
Nonenzymatic functions of acetylcholinesterase splice variants in the developmental neurotoxicity of organophosphates: chlorpyrifos, chlorpyrifos oxon, and diazinon. | Environmental health perspectives 20070101 |
Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro. | Journal of applied toxicology : JAT 20070101 |
Nano-enabled synthetic biology. | Molecular systems biology 20070101 |
Effect of pre-germinated brown rice intake on diabetic neuropathy in streptozotocin-induced diabetic rats. | Nutrition & metabolism 20070101 |
Impact of receptor changes on treatment of status epilepticus. | Epilepsia 20070101 |
Effects of eprosartan on serum metabolic parameters in patients with essential hypertension. | The open cardiovascular medicine journal 20070101 |
The effect of chronic consumption of paraoxon on basal and pentagastrin-stimulated gastric acid and pepsin secretion in rats. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20070101 |
New K-Oximes (K-27 and K-48) in Comparison with Obidoxime (LuH-6), HI-6, Trimedoxime (TMB-4), and Pralidoxime (2-PAM): Survival in Rats Exposed IP to the Organophosphate Paraoxon. | Toxicology mechanisms and methods 20070101 |
Distribution profile of paraoxonase phenotypes among the Gujaratis. | Indian journal of human genetics 20070101 |
Carboxylesterase activities toward pesticide esters in crops and weeds. | Phytochemistry 20061201 |
Detection of carbamic and organophosphorous pesticides in water samples using a cholinesterase biosensor based on Prussian Blue-modified screen-printed electrode. | Analytica chimica acta 20061124 |
Effect of pyridostigmine, pralidoxime and their combination on survival and cholinesterase activity in rats exposed to the organophosphate paraoxon. | Archives of toxicology 20061101 |
Acetylcholinesterase inhibition: does it explain the toxicity of organophosphorus compounds? | Archives of toxicology 20061101 |
Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. | Bioorganic & medicinal chemistry letters 20061101 |
Determination of parathion in biological fluids by means of direct solid-phase microextraction. | Analytical and bioanalytical chemistry 20061101 |
Determination of organophosphorous pesticides by a novel biosensor based on localized surface plasmon resonance. | Biosensors & bioelectronics 20061015 |
Modulation of paraoxon toxicity by the cannabinoid receptor agonist WIN 55,212-2. | Toxicology 20061003 |
Effects of an organophosphate on Daphnia magna at suborganismal and organismal levels: implications for population dynamics. | Ecotoxicology and environmental safety 20061001 |
Detection of organophosphorus compounds by covalently immobilized organophosphorus hydrolase. | Analytical chemistry 20061001 |
Mineralization of paraoxon and its use as a sole C and P source by a rationally designed catabolic pathway in Pseudomonas putida. | Applied and environmental microbiology 20061001 |
Organophosphorus hydrolase at the air-water interface: secondary structure and interaction with paraoxon. | Biomacromolecules 20061001 |
Ranitidine in acute high-dose organophosphate exposure in rats: effect of the time-point of administration and comparison with pyridostigmine. | Basic & clinical pharmacology & toxicology 20061001 |
Organophosphorus insecticides extraction and heterogeneous oxidation on column for analysis with an acetylcholinesterase (AChE) biosensor. | Analytica chimica acta 20060925 |
Potentiometric titration of metal ions in ethanol. | Inorganic chemistry 20060918 |
Comparison of chromaffin cells from several animal sources for their use as an in vitro model to study the mechanism of organophosphorous toxicity. | Toxicology letters 20060910 |
Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters. | Biochimica et biophysica acta 20060901 |
Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions. | Chemical research in toxicology 20060901 |
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents. | Proceedings of the National Academy of Sciences of the United States of America 20060829 |
High-level expression of recombinant human paraoxonase 1 Q in silkworm larvae (Bombyx mori). | Applied microbiology and biotechnology 20060801 |
Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH). | Journal of toxicology and environmental health. Part A 20060801 |
The functional consequences of paraoxon exposure in central neurones of land snail, Caucasotachea atrolabiata, are partly mediated through modulation of Ca2+ and Ca2+-activated K+-channels. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060801 |
Effects of some antibiotics on paraoxonase from human serum in vitro and from mouse serum and liver in vivo. | Biological & pharmaceutical bulletin 20060801 |
Lead exposure is associated with decreased serum paraoxonase 1 (PON1) activity and genotypes. | Environmental health perspectives 20060801 |
Development of a dynamic model for real-time determination of membrane-bound acetylcholinesterase activity upon perfusion with inhibitors and reactivators. | Biochemical pharmacology 20060728 |
Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetylcholinesterase by highly toxic organophosphorus compounds. | Biochemical pharmacology 20060728 |
A magnetic biomimetic nanocatalyst for cleaving phosphoester and carboxylic ester bonds under mild conditions. | Organic letters 20060720 |
On-chip integrated hydrolysis, fluorescent labeling, and electrophoretic separation utilized for acetylcholinesterase assay. | Analytica chimica acta 20060707 |
Diazinon, chlorpyrifos and parathion are metabolised by multiple cytochromes P450 in human liver. | Toxicology 20060705 |
Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. | Environmental health perspectives 20060701 |
Baculovirus expression of BmAChE3, a cDNA encoding an acetylcholinesterase of Boophilus microplus (Acari: Ixodidae). | Journal of medical entomology 20060701 |
Unique regulation of the active site of the serine esterase S-formylglutathione hydrolase. | Journal of molecular biology 20060602 |
Relationship of serum paraoxonase 1 activity and paraoxonase 1 genotype to risk of systemic lupus erythematosus. | Arthritis and rheumatism 20060601 |
Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice. | The European journal of neuroscience 20060601 |
[Effects of organophosphorus insecticides on G protein-coupled receptor kinase-2 mediated phosphorylation of M2 muscarinic receptors]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20060601 |
Microbial biosensor for direct determination of nitrophenyl-substituted organophosphate nerve agents using genetically engineered Moraxella sp. | Analytica chimica acta 20060524 |
Improved access to 2-O-monobenzyl ethers of beta-cyclodextrin as precursors of catalysts for organophosphoryl esters hydrolysis. | Carbohydrate research 20060522 |
Each lipase has a unique sensitivity profile for organophosphorus inhibitors. | Toxicological sciences : an official journal of the Society of Toxicology 20060501 |
Lateral parabrachial lesions disrupt paraoxon-induced conditioned flavor avoidance. | Toxicological sciences : an official journal of the Society of Toxicology 20060501 |
Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells. | Environmental health perspectives 20060501 |
Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity. | Environmental health perspectives 20060501 |
Effects of the organophosphate paraoxon-methyl on survival and reproduction of Daphnia magna: importance of exposure duration and recovery. | Environmental toxicology and chemistry 20060501 |
Paraoxon suppresses Ca(2+) spike and afterhyperpolarization in snail neurons: Relevance to the hyperexcitability induction. | Brain research 20060414 |
Concentration-dependent kinetics of acetylcholinesterase inhibition by the organophosphate paraoxon. | Toxicological sciences : an official journal of the Society of Toxicology 20060401 |
Tiapride pre-treatment in acute exposure to paraoxon: comparison of effects of administration at different points-in-time in rats. | Molecular and cellular biochemistry 20060401 |
Functional analysis of organophosphorus hydrolase variants with high degradation activity towards organophosphate pesticides. | Protein engineering, design & selection : PEDS 20060301 |
Semiautomated method for determination of serum paraoxonase activity using paraoxon as substrate. | Clinical chemistry 20060301 |
Purification and characterization of an esterase isozyme involved in hydrolysis of organophosphorus compounds from an insecticide resistant pest, Helicoverpa armigera (Lepidoptera: Noctüidae). | Biochimica et biophysica acta 20060301 |
PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. | Pharmacogenetics and genomics 20060301 |
Structural requirements of acetylcholinesterase reactivators. | Mini reviews in medicinal chemistry 20060301 |
Paraoxonase/arylesterase in serum of patients with type II diabetes mellitus. | Acta pharmaceutica (Zagreb, Croatia) 20060301 |
Peptidolipid as binding site of acetylcholinesterase: molecular recognition of paraoxon in Langmuir films. | Langmuir : the ACS journal of surfaces and colloids 20060227 |
Sensitivity and specificity improvement of an ion sensitive field effect transistors-based biosensor for potato glycoalkaloids detection. | Journal of agricultural and food chemistry 20060208 |
Degradation mechanism and the toxicity assessment in TiO2 photocatalysis and photolysis of parathion. | Chemosphere 20060201 |
Biosensor based on self-assembling acetylcholinesterase on carbon nanotubes for flow injection/amperometric detection of organophosphate pesticides and nerve agents. | Analytical chemistry 20060201 |
Paraoxon-induced ultrastructural growth changes of rat cultured hippocampal cells in neurobasal/B27. | Toxicology 20060116 |
Screen-printed bienzymatic sensor based on sol-gel immobilized Nippostrongylusbrasiliensis acetylcholinesterase and a cytochrome P450 BM-3 (CYP102-A1) mutant. | Biosensors & bioelectronics 20060115 |
Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents. | Journal of medicinal chemistry 20060112 |
A novel butyrylcholinesterase from serum of Leporinus macrocephalus, a Neotropical fish. | Biochimie 20060101 |
Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon. | Journal of applied toxicology : JAT 20060101 |
Interactive toxicity of chlorpyrifos and parathion in neonatal rats: role of esterases in exposure sequence-dependent toxicity. | Toxicology and applied pharmacology 20060101 |
A case for revisiting the safety of pesticides: a closer look at neurodevelopment. | Environmental health perspectives 20060101 |
A model for linking the effects of parathion in soil to its degradation and bioavailability kinetics. | Journal of environmental quality 20060101 |
Amphenicol and macrolide derived antibiotics inhibit paraoxonase enzyme activity in human serum and human hepatoma cells (HepG2) in vitro. | Biochemistry. Biokhimiia 20060101 |
Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: survival in rats exposed to the organophosphate paraoxon. | Journal of applied toxicology : JAT 20060101 |
Comparison of cholin- and carboxylesterase enzyme inhibition and visible effects in the zebra fish embryo bioassay under short-term paraoxon-methyl exposure. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20060101 |
Roles of paraoxonase and oxidative stress in adolescents with uraemic, essential or obesity-induced hypertension. | Kidney & blood pressure research 20060101 |
Paraoxonase-1 (PON1) activity, but not PON1(Q192R) phenotype, is a predictor of coronary artery disease in a middle-aged Serbian population. | Clinical chemistry and laboratory medicine 20060101 |
Activity of paraoxonase 1 (PON1) and its relationship to markers of lipoprotein oxidation in healthy Slovaks. | Acta biochimica Polonica 20060101 |
Solvent deuterium kinetic isotope effects for the methanolyses of neutral C=O, P=O and P=S esters catalyzed by a triazacyclododecane : Zn(2+)-methoxide complex. | Organic & biomolecular chemistry 20051221 |
Serum arylesterase and paraoxonase activity in patients with chronic hepatitis. | World journal of gastroenterology 20051214 |
Role of metabolism in parathion-induced hepatotoxicity and immunotoxicity. | Journal of toxicology and environmental health. Part A 20051210 |
Closed and open conformations of the lid domain induce different patterns of human pancreatic lipase antigenicity and immunogenicity. | Biochimica et biophysica acta 20051201 |
Significant differences in the disposition of cyclic prodrugs of opioid peptides in rats and guinea pigs following IV administration. | Journal of pharmaceutical sciences 20051201 |
Detoxification of the organophosphate nerve agent coumaphos using organophosphorus hydrolase immobilized on cellulose materials. | Journal of industrial microbiology & biotechnology 20051201 |
[Intravenous oxygen therapy increases the activity of the antioxidative and antiatherogenic serum enzyme paraoxonase 1]. | Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine 20051201 |
Synthesis and bioactivity of new phosphorylated R,R'-substituted sulfoximines. | Molecules (Basel, Switzerland) 20051130 |
Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma. | Biochemical pharmacology 20051125 |
Reduction of neuropathy target esterase does not affect neuronal differentiation, but moderate expression induces neuronal differentiation in human neuroblastoma (SK-N-SH) cell line. | Brain research. Molecular brain research 20051118 |
Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. | Toxicology 20051115 |
Highly sensitive and selective amperometric microbial biosensor for direct determination of p-nitrophenyl-substituted organophosphate nerve agents. | Environmental science & technology 20051115 |
Microfluidic biosensor based on an array of hydrogel-entrapped enzymes. | Analytical chemistry 20051101 |
Effects of oximes on muscle force and acetylcholinesterase activity in isolated mouse hemidiaphragms exposed to paraoxon. | Toxicology 20051030 |
Structural and mutational studies of organophosphorus hydrolase reveal a cryptic and functional allosteric-binding site. | Archives of biochemistry and biophysics 20051015 |
The thermodynamics of phosphate versus phosphorothioate ester hydrolysis. | The Journal of organic chemistry 20051014 |
Cholin- and carboxylesterase activities in developing zebrafish embryos (Danio rerio) and their potential use for insecticide hazard assessment. | Aquatic toxicology (Amsterdam, Netherlands) 20051005 |
Squaric monoamide monoester as a new class of reactive immunization hapten for catalytic antibodies. | Bioorganic & medicinal chemistry letters 20051001 |
Iron-ascorbic acid-induced oxidant stress and its quenching by paraoxonase 1 in HDL and the liver: comparison between humans and rats. | Journal of cellular biochemistry 20051001 |
Assessment of paraoxonase 1 activity and malondialdehyde levels in patients with rheumatoid arthritis. | Clinical biochemistry 20051001 |
Stability of oxymethyl-modified coumarinic acid cyclic prodrugs of diastereomeric opioid peptides in biological media from various animal species including human. | Journal of pharmaceutical sciences 20051001 |
Acetylcholinesterase sensor based on screen-printed carbon electrode modified with prussian blue. | Analytical and bioanalytical chemistry 20051001 |
Inhibition of N-methyl-D-aspartate receptors increases paraoxon-induced apoptosis in cultured neurons. | Toxicology and applied pharmacology 20051001 |
Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood. | Environmental health perspectives 20051001 |
Effects of paraoxon and ethylparathion on choline oxidase from Alcaligenes species: inhibition and denaturation. | International journal of biological macromolecules 20050928 |
Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives. | Talanta 20050915 |
Detoxification of organophosphate nerve agents by immobilized dual functional biocatalysts in a cellulose hollow fiber bioreactor. | Biotechnology and bioengineering 20050805 |
Paraoxonase-1 (PON-1) genotype and activity and in vivo oxidized plasma low-density lipoprotein in Type II diabetes. | Clinical science (London, England : 1979) 20050801 |
Serum paraoxonase activity in dairy cows during pregnancy. | Research in veterinary science 20050801 |
Sensitive detection of organophosphates in river water by means of a piezoelectric biosensor. | Analytical and bioanalytical chemistry 20050801 |
Synthesis of 2-substituted beta-cyclodextrin derivatives with a hydrolytic activity against the organophosphorylester paraoxon. | European journal of medicinal chemistry 20050701 |
Disposable biosensor test for organophosphate and carbamate insecticides in milk. | Journal of agricultural and food chemistry 20050629 |
Formation and disposition of diethylphosphoryl-obidoxime, a potent anticholinesterase that is hydrolyzed by human paraoxonase (PON1). | Biochemical pharmacology 20050615 |
Genetic polymorphisms and activity of PON1 in a Mexican population. | Toxicology and applied pharmacology 20050615 |
Paraoxonase activity in Greek migrants and Anglo-Celtic persons in the Melbourne Collaborative Cohort Study: relationship to dietary markers. | European journal of nutrition 20050601 |
Differential effect of antioxidant treatment on plasma and tissue paraoxonase activity in hyperleptinemic rats. | Pharmacological research 20050601 |
Increased expression of a bacterial phosphotriesterase in Escherichia coli through directed evolution. | Protein expression and purification 20050601 |
In vitro assessment of the genotoxicity of ethyl paraoxon in newborns and adults. | Human & experimental toxicology 20050601 |
Modeling impact of parathion and its metabolite paraoxon on the nematode Caenorhabditis elegans in soil. | Environmental toxicology and chemistry 20050601 |
Overview of molecular, cellular, and genetic neurotoxicology. | Neurologic clinics 20050501 |
Optical solid-state detection of organophosphates using organophosphorus hydrolase. | Biosensors & bioelectronics 20050415 |
Inhibition of the acetycholine esterase-stimulated growth of Au nanoparticles: nanotechnology-based sensing of nerve gases. | Nano letters 20050401 |
Metal clad leaky waveguides for chemical and biosensing applications. | Biosensors & bioelectronics 20050315 |
(CdSe)ZnS quantum dots and organophosphorus hydrolase bioconjugate as biosensors for detection of paraoxon. | The journal of physical chemistry. B 20050310 |
Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia. | Journal of lipid research 20050301 |
The interaction between OPH and paraoxon at the air-water interface studied by AFM and epifluorescence microscopies. | Colloids and surfaces. B, Biointerfaces 20050210 |
Direct determination of p-nitrophenyl substituent organophosphorus nerve agents using a recombinant Pseudomonas putida JS444-modified Clark oxygen electrode. | Journal of agricultural and food chemistry 20050209 |
Activation, inhibition, and destabilization of Thermomyces lanuginosus lipase by detergents. | Biochemistry 20050208 |
Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry. | Toxicological sciences : an official journal of the Society of Toxicology 20050201 |
Protective drugs in acute large-dose exposure to organophosphates: a comparison of metoclopramide and tiapride with pralidoxime in rats. | Anesthesia and analgesia 20050201 |
Aqueous sol-gel encapsulation of genetically engineered Moraxella spp. cells for the detection of organophosphates. | Biosensors & bioelectronics 20050115 |
Weak inhibitors protect cholinesterases from strong inhibitors (paraoxon): in vitro effect of ranitidine. | Journal of applied toxicology : JAT 20050101 |
Protective agents in acute high-dose organophosphate exposure: comparison of ranitidine with pralidoxime in rats. | Journal of applied toxicology : JAT 20050101 |
Antileukemic activity and cellular metabolism of the aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07). | Arzneimittel-Forschung 20050101 |
Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells. | Neurotoxicity research 20050101 |
[Changes of parameters of functions of respiratory and cardiovascular systems of different age rats under influence of small doses of cholinesterase inhibitor Phosphacol]. | Zhurnal evoliutsionnoi biokhimii i fiziologii 20050101 |
Paraoxonase 1 status in the Thai population. | Journal of human genetics 20050101 |
Improved degradation of organophosphorus nerve agents and p-nitrophenol by Pseudomonas putida JS444 with surface-expressed organophosphorus hydrolase. | Biotechnology progress 20050101 |
[Finding cholinesterase in endotheliocytes: cholinesterase inhibition by organophosphorus compounds leads to endotheliocyte deformation]. | Eksperimental'naia i klinicheskaia farmakologiia 20050101 |
Lack of association between carotid intima-media thickness and PAF-acetylhydrolase mass and activity in patients with primary hyperlipidemia. | Angiology 20050101 |
Effect of metoclopramide and ranitidine on the inhibition of human AChE by VX in vitro. | Journal of applied toxicology : JAT 20050101 |
Weak inhibitors protect cholinesterases from strong inhibitors (paraoxon): in vitro effect of tiapride. | Journal of applied toxicology : JAT 20050101 |
Metoclopramide-induced central nervous system depression in the chicken. | BMC veterinary research 20050101 |
Liver prenylated methylated protein methyl esterase is an organophosphate-sensitive enzyme. | Journal of biochemical and molecular toxicology 20050101 |
Bis(dialkylamide)hydrogen dibromobromate precursors of hypobromite ion in reactions with nerve and blister agent simulants. | The Journal of organic chemistry 20041224 |
La3+-catalyzed methanolysis of O,O-diethyl S-(p-nitrophenyl) phosphorothioate and O,O-diethyl S-phenyl phosphorothioate. Millions-fold acceleration of the destruction of V-agent simulants. | Organic & biomolecular chemistry 20041207 |
Increased susceptibility to adult paraoxon exposure in mice neonatally exposed to nicotine. | Toxicological sciences : an official journal of the Society of Toxicology 20041201 |
Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids. | Journal of lipid research 20041201 |
Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. | Toxicology and applied pharmacology 20041201 |
Cardiac responses of Pacific oyster Crassostrea gigas to agents modulating cholinergic function. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041201 |
Determinants of homocysteine-thiolactonase activity of the paraoxonase-1 (PON1) protein in humans. | Cellular and molecular biology (Noisy-le-Grand, France) 20041201 |
Methyl-paraoxon comparative inhibition kinetics for acetylcholinesterases from brain of neotropical fishes. | Toxicology letters 20041102 |
Hydrolysis of carbaryl by human serum albumin. | Archives of toxicology 20041101 |
Sonochemically fabricated enzyme microelectrode arrays for the environmental monitoring of pesticides. | Biosensors & bioelectronics 20041101 |
Thermostable esterase from a thermoacidophilic archaeon: purification and characterization for enzymatic resolution of a chiral compound. | Bioscience, biotechnology, and biochemistry 20041101 |
Cloning and characterization of the acid lipase from castor beans. | The Journal of biological chemistry 20041029 |
Zn2+-catalyzed methanolysis of phosphate triesters: a process for catalytic degradation of the organophosphorus pesticides paraoxon and fenitrothion. | Inorganic chemistry 20041018 |
Evaluation of mechanisms of azinphos-methyl resistance in the codling moth Cydia pomonella (L.). | Archives of insect biochemistry and physiology 20041001 |
Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model. | Biochimica et biophysica acta 20041001 |
Glutathione S-transferase in the insect Apis mellifera macedonica kinetic characteristics and effect of stress on the expression of GST isoenzymes in the adult worker bee. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041001 |
Overestimation of plasma nonesterified fatty acid concentrations in heparinized blood. | Circulation 20040928 |
Further assessment of an in vitro screen that may help identify organophosphorus pesticides that are more acutely toxic to the young. | Journal of toxicology and environmental health. Part A 20040924 |
Retrospective detection of exposure to nerve agents: analysis of phosphofluoridates originating from fluoride-induced reactivation of phosphylated BuChE. | Archives of toxicology 20040901 |
A guinea pig hippocampal slice model of organophosphate-induced seizure activity. | The Journal of pharmacology and experimental therapeutics 20040801 |
Comparison of chlorpyrifos-oxon and paraoxon acetylcholinesterase inhibition dynamics: potential role of a peripheral binding site. | Toxicological sciences : an official journal of the Society of Toxicology 20040801 |
Effect of short term treatment with simvastatin and atorvastatin on lipids and paraoxonase activity in patients with hyperlipoproteinaemia. | Current medical research and opinion 20040801 |
Might the kinetic behavior of hormone-sensitive lipase reflect the absence of the lid domain? | Biochemistry 20040727 |
Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver. | FEBS letters 20040716 |
Neurofilament 200 as an indicator of differences between mipafox and paraoxon sensitivity in Sy5Y neuroblastoma cells. | Journal of toxicology and environmental health. Part A 20040709 |
[Decrease of paraoxonase activity in the first day after abdominal operations in women]. | Ginekologia polska 20040701 |
Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity. | Toxicology letters 20040615 |
Effect of organophosphorus hydrolysing enzymes on obidoxime-induced reactivation of organophosphate-inhibited human acetylcholinesterase. | Archives of toxicology 20040601 |
Mechanism for the hydrolysis of organophosphates by the bacterial phosphotriesterase. | Biochemistry 20040518 |
Interactive toxicity of the organophosphorus insecticides chlorpyrifos and methyl parathion in adult rats. | Toxicology and applied pharmacology 20040415 |
Interactive effects of paraoxon and pyridostigmine on blood-brain barrier integrity and cholinergic toxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20040401 |
A fluorogenic substrate for detection of organophosphatase activity. | Analytical biochemistry 20040401 |
Detoxification of organophosphorus compounds by recombinant carboxylesterase from an insecticide-resistant mosquito and oxime-induced amplification of enzyme activity. | Environmental toxicology 20040401 |
Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis. | Experimental gerontology 20040401 |
Protective effect of polyurethane immobilized human butyrylcholinesterase against parathion inhalation in rat. | Environmental toxicology and pharmacology 20040401 |
Whole cell-enzyme hybrid amperometric biosensor for direct determination of organophosphorous nerve agents with p-nitrophenyl substituent. | Biotechnology and bioengineering 20040330 |
Activation of phosphorothionate pesticides based on a cytochrome P450 BM-3 (CYP102 A1) mutant for expanded neurotoxin detection in food using acetylcholinesterase biosensors. | Analytical chemistry 20040315 |
Spine density and dendritic branching pattern of hippocampal CA1 pyramidal neurons in neonatal rats chronically exposed to the organophosphate paraoxon. | Neurotoxicology 20040301 |
Identification of factors responsible for insecticide resistance in Helicoverpa armigera. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20040301 |
Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon. | Toxicological sciences : an official journal of the Society of Toxicology 20040201 |
Hydrolysis of organophosphorus compounds by an esterase isozyme from insecticide resistant pest Helicoverpa armigera. | Indian journal of experimental biology 20040201 |
Pharmacogenetics of paraoxonases: a brief review. | Naunyn-Schmiedeberg's archives of pharmacology 20040101 |
Effect of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins) on tissue paraoxonase 1 and plasma platelet activating factor acetylhydrolase activities. | Journal of cardiovascular pharmacology 20040101 |
The effect of fluoride on the scavenging of organophosphates by human butyrylcholinesterase in buffer solutions and human plasma. | Toxicology and applied pharmacology 20040101 |
Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populations. | BMC evolutionary biology 20040101 |
Long-term functional neurotoxicity of paraoxon and chlorpyrifos: behavioural and pharmacological evidence. | Neurotoxicology and teratology 20040101 |
Detection and classification of organophosphate nerve agent simulants using support vector machines with multiarray sensors. | Journal of chemical information and computer sciences 20040101 |
Paraoxonase 55 and 192 polymorphism and its relationship to serum paraoxonase activity and serum lipids in Turkish patients with non-insulin dependent diabetes mellitus. | Cell biochemistry and function 20040101 |
Paraoxonase 1 and platelet-activating factor acetylhydrolase activities in patients with low hdl-cholesterol levels with or without primary hypertriglyceridemia. | Archives of medical research 20040101 |
The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis. | BMC genetics 20040101 |
In vivo metoclopramide protection of cholinesterase from paraoxon inhibition: direct comparison with pralidoxime in subchronic low-dose exposure. | Journal of applied toxicology : JAT 20040101 |
Alterations of paraoxonase and platelet-activating factor acetylhydrolase activities in patients on peritoneal dialysis. | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20040101 |
Organophosphate nerve agent detection with europium complexes. | TheScientificWorldJournal 20040101 |
Serum paraoxonase activity in uremic predialysis and hemodialysis patients. | Journal of nephrology 20040101 |
In vitro and in vivo pharmacokinetic features and metabolism of the novel cytotoxic nucleoside analog 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate] (Compound 003). | Arzneimittel-Forschung 20040101 |
A label-free electrochemical immunosensor based on gold nanoparticles for detection of paraoxon. | Talanta 20031223 |
Significant and differential acceleration of dephosphorylation of the insecticides, paraoxon and parathion, caused by alkali metal ethoxides. | Chemical communications (Cambridge, England) 20031221 |
Levels of paraoxonase and arylesterase activities and malondialdehyde in workers exposed to ionizing radiation. | Cell biochemistry and function 20031201 |
Morphological effects of neuropathy-inducing organophosphorus compounds in primary dorsal root ganglia cell cultures. | Neurotoxicology 20031201 |
Pharmacokinetics and metabolism of 14C-levetiracetam, a new antiepileptic agent, in healthy volunteers. | European journal of clinical pharmacology 20031101 |
Paraoxonase activity and genetic polymorphisms in greenhouse workers with long term pesticide exposure. | Human & experimental toxicology 20031101 |
New principle of direct real-time monitoring of the interaction of cholinesterase and its inhibitors by piezolectric biosensor. | Biosensors & bioelectronics 20031001 |
Metoclopramide protection of cholinesterase from paraoxon inhibition. | Veterinary and human toxicology 20031001 |
Effects of daily stress or repeated paraoxon exposures on subacute pyridostigmine toxicity in rats. | Archives of toxicology 20031001 |
Paraoxonase (Pon1) Q192R polymorphism and serum Pon1 activity in diabetic patients on maintenance hemodialysis. | Clinical nephrology 20031001 |
Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF mass spectrometry. | Biochemistry 20030923 |
Leptin decreases plasma paraoxonase 1 (PON1) activity and induces oxidative stress: the possible novel mechanism for proatherogenic effect of chronic hyperleptinemia. | Atherosclerosis 20030901 |
Inhibitors of hepatic microsomal triacylglycerol hydrolase decrease very low density lipoprotein secretion. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901 |
Photothermal bioanalytical methods for pesticide toxicity testing. | Arhiv za higijenu rada i toksikologiju 20030901 |
Combined forced running stress and subclinical paraoxon exposure have little effect on pyridostigmine-induced acute toxicity in rats. | Toxicology 20030828 |
Blockage of transcription as a trigger for p53 accumulation by 2-acetylaminofluorene DNA-adducts. | Life sciences 20030822 |
Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase. | Biochemical pharmacology 20030801 |
Sequential structural changes of Escherichia coli thioesterase/protease I in the serial formation of Michaelis and tetrahedral complexes with diethyl p-nitrophenyl phosphate. | Biochemistry 20030715 |
Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways. | Toxicology and applied pharmacology 20030701 |
Enhancement of the catalytic activity of an artificial phosphotriesterase using a molecular imprinting technique. | Biotechnology letters 20030701 |
Billion-fold acceleration of the methanolysis of paraoxon promoted by La(OTf)3 in methanol. | Journal of the American Chemical Society 20030625 |
Low paraoxonase activity predicts coronary events in the Caerphilly Prospective Study. | Circulation 20030610 |
Paraoxonase-1 promoter haplotypes and serum paraoxonase: a predominant role for polymorphic position - 107, implicating the Sp1 transcription factor. | The Biochemical journal 20030601 |
Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man? | Archives of toxicology 20030601 |
[Effect of paraoxon and chlorpyrifos on the nicotinic autoreceptor function in rat cortical synaptosomes]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20030601 |
Structure-activity relationship on human serum paraoxonase (PON1) using substrate analogues and inhibitors. | Bioorganic & medicinal chemistry letters 20030519 |
Fenofibrate induces HDL-associated PAF-AH but attenuates enzyme activity associated with apoB-containing lipoproteins. | Journal of lipid research 20030501 |
Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice. | The Journal of pharmacology and experimental therapeutics 20030501 |
Optical biosensor for simultaneous detection of captan and organophosphorus compounds. | Biosensors & bioelectronics 20030501 |
Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status. | Pharmacogenetics 20030501 |
Properties of phenyl valerate esterase activities from chicken serum are comparable with soluble esterases of peripheral nerves in relation with organophosphorus compounds inhibition. | Toxicology letters 20030430 |
Modulation of the mutagenicity of heterocyclic amines by organophosphate insecticides and their metabolites. | Mutation research 20030420 |
Lack of association between serum paraoxonase 1 activities and increased oxidized low-density lipoprotein levels in impaired glucose tolerance and newly diagnosed diabetes mellitus. | The Journal of clinical endocrinology and metabolism 20030401 |
PON1-192 phenotype and genotype assessments in 918 subjects of the Stanislas cohort study. | Clinical chemistry and laboratory medicine 20030401 |
Ghrelin can bind to a species of high density lipoprotein associated with paraoxonase. | The Journal of biological chemistry 20030314 |
Flow injection amperometric detection of OP nerve agents based on an organophosphorus-hydrolase biosensor detector. | Biosensors & bioelectronics 20030301 |
Detection of pesticides using an amperometric biosensor based on ferophthalocyanine chemically modified carbon paste electrode and immobilized bienzymatic system. | Biosensors & bioelectronics 20030301 |
Oral treatment of organophosphate poisoning in mice. | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20030301 |
[Preparation of monoclonal antibodies against neurotoxic agent raised from an organophosphorus hapten and its characterization]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20030301 |
Layer-by-layer self-assembled chitosan/poly(thiophene-3-acetic acid) and organophosphorus hydrolase multilayers. | Journal of the American Chemical Society 20030219 |
Coordination number of zinc ions in the phosphotriesterase active site by molecular dynamics and quantum mechanics. | Journal of computational chemistry 20030201 |
Evaluating reptile exposure to cholinesterase-inhibiting agrochemicals by serum butyrylcholinesterase activity. | Environmental toxicology and chemistry 20030201 |
Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep. | Pharmacogenetics 20030201 |
Association between human paraoxonase gene polymorphism and chronic symptoms in pesticide-exposed workers. | Journal of occupational and environmental medicine 20030201 |
Utilization of monocrotophos as phosphorus source by Pseudomonas aeruginosa F10B and Clavibacter michiganense subsp. insidiosum SBL 11. | Canadian journal of microbiology 20030201 |
Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds. | Toxicology and applied pharmacology 20030115 |
Thermally triggered purification and immobilization of elastin-OPH fusions. | Biotechnology and bioengineering 20030105 |
Effects of chronic dermal exposure to nonlethal doses of methyl parathion on brain regional acetylcholinesterase and muscarinic cholinergic receptors in female rats. | Journal of neuroscience research 20030101 |
Influence of paraoxon (POX) and parathion (PAT) on apoptosis: a possible mechanism for toxicity in low-dose exposure. | Journal of applied toxicology : JAT 20030101 |
Intravenous pyruvic acid application in minipigs partially protects acetylcholine-esteratic but not butyrylcholine-esteratic activity in plasma from inhibition by paraoxon. | Journal of applied toxicology : JAT 20030101 |
In vitro protection of plasma cholinesterases by metoclopramide from inhibition by paraoxon. | Journal of applied toxicology : JAT 20030101 |
Paraoxonase (PON 1) as a biomarker of susceptibility for organophosphate toxicity. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101 |
Use of atropine-treated Daphnia magna survival for detection of environmental contamination by acetylcholinesterase inhibitors. | Ecotoxicology and environmental safety 20030101 |
Lack of association between Alzheimer's disease and Gln-Arg 192 Q/R polymorphism of the PON-1 gene in an Italian population. | Dementia and geriatric cognitive disorders 20030101 |
Biochemical detection of esterases in the adult female integument of organophosphate-resistant Boophilus microplus (Acari: Ixodidae). | Journal of medical entomology 20030101 |
PON1 paraoxonase activity is reduced during HDL oxidation and is an indicator of HDL antioxidant capacity. | Free radical research 20030101 |
Langmuir and Langmuir-Blodgett films of organophosphorus acid anhydrolase. | Biomacromolecules 20030101 |
Distribution of serum paraoxon hydrolyzing activity in a large Spanish population using a routine automized method in clinical laboratory. | Journal of analytical toxicology 20030101 |
In vitro protection of red blood cell acetylcholinesterase by metoclopramide from inhibition by organophosphates (paraoxon and mipafox). | Journal of applied toxicology : JAT 20030101 |
Modeling of sorption and biodegradation of parathion and its metabolite paraoxon in soil. | Journal of environmental quality 20030101 |
The ratio of serum paraoxonase/arylesterase activity using an improved assay for arylesterase activity to discriminate PON1(R192) from PON1(Q192). | Journal of atherosclerosis and thrombosis 20030101 |
Human parathion poisoning. A toxicokinetic analysis. | Toxicological reviews 20030101 |
Rapid assessment of organophosphorous/carbamate exposure in the bivalve mollusc Mytilus edulis using combined esterase activities as biomarkers. | Aquatic toxicology (Amsterdam, Netherlands) 20021203 |
Synthesis and stability study of a modified phenylpropionic acid linker-based esterase-sensitive prodrug. | Bioorganic & medicinal chemistry letters 20021202 |
Comparative inhibition kinetics for acetylcholinesterases extracted from organophosphate resistant and susceptible strains of Boophilus microplus (Acari: Ixodidae). | Journal of economic entomology 20021201 |
In vitro stability and in vivo pharmacokinetic studies of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs. | The Journal of pharmacology and experimental therapeutics 20021101 |
An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion. | Toxicological sciences : an official journal of the Society of Toxicology 20021101 |
Lizard cholinesterases as biomarkers of pesticide exposure: enzymological characterization. | Environmental toxicology and chemistry 20021101 |
Paraoxonase 1 activity: a new vascular marker of dementia? | Annals of the New York Academy of Sciences 20021101 |
Assays for the classification of two types of esterases: carboxylic ester hydrolases and phosphoric triester hydrolases. | Current protocols in toxicology 20021101 |
Equipotent cholinesterase reactivation in vitro by the nerve agent antidotes HI 6 dichloride and HI 6 dimethanesulfonate. | Archives of toxicology 20021001 |
Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides. | Toxicology letters 20020905 |
Convenient and rapid detection of pesticides in extracts of sheep wool. | Biosensors & bioelectronics 20020901 |
Detection of organophosphorus insecticides with immobilized acetylcholinesterase - comparative study of two enzyme sensors. | Analytical and bioanalytical chemistry 20020901 |
[Reactivation and aging of acetylcholinesterase in human brain inhibited by phoxim and phoxim oxon in vitro]. | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20020901 |
Vitamin C and E intake is associated with increased paraoxonase activity. | Arteriosclerosis, thrombosis, and vascular biology 20020801 |
Synthesis of a novel cyclic prodrug of RGD peptidomimetic to improve its cell membrane permeation. | Bioorganic chemistry 20020801 |
Continuous system modeling of equilibrium dialysis for determinations of tissue partitioning of parathion and paraoxon. | Toxicology letters 20020721 |
Intravenous L-lactate application in minipigs partially protects acetylcholinesteratic but not butyrylcholinesteratic activity in plasma from inhibition by paraoxon. | Critical care medicine 20020701 |
Nanocrystalline metal oxides as destructive adsorbents for organophosphorus compounds at ambient temperatures. | Chemistry (Weinheim an der Bergstrasse, Germany) 20020603 |
Effects of PCB exposure on the toxic impact of organophosphorus insecticides. | Toxicological sciences : an official journal of the Society of Toxicology 20020601 |
Characterization of butyrylcholinesterase antagonism of cocaine-induced hyperactivity. | Drug metabolism and disposition: the biological fate of chemicals 20020601 |
Reactivation of immobilized acetyl cholinesterase in an amperometric biosensor for organophosphorus pesticide. | Biochimica et biophysica acta 20020520 |
Novel irreversible butyrylcholinesterase inhibitors: 2-chloro-1-(substituted-phenyl)ethylphosphonic acids. | Bioorganic & medicinal chemistry 20020501 |
Human and rodent carboxylesterases: immunorelatedness, overlapping substrate specificity, differential sensitivity to serine enzyme inhibitors, and tumor-related expression. | Drug metabolism and disposition: the biological fate of chemicals 20020501 |
Paraoxonase1-192 polymorphism modulates the effects of regular and acute exercise on paraoxonase1 activity. | Journal of lipid research 20020501 |
Paraoxonase Gln-Arg(192) and Leu-Met(55) gene polymorphisms and enzyme activity in a population with a low rate of coronary heart disease. | Clinical biochemistry 20020501 |
Effect of organophosphate intoxication on human serum paraoxonase. | Human & experimental toxicology 20020501 |
Addition of Polybrene improves stability of organophosphate hydrolase immobilized in poly(vinyl alcohol) cryogel carrier. | Journal of biochemical and biophysical methods 20020418 |
Mechanisms of resistance to organophosphates in Tetranychus urticae (Acari: Tetranychidae) from Greece. | Insect biochemistry and molecular biology 20020401 |
Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia. | European archives of psychiatry and clinical neuroscience 20020401 |
Flow-injection amperometric determination of pesticides on the basis of their inhibition of immobilized acetylcholinesterases of different origin. | Analytical and bioanalytical chemistry 20020401 |
Sensitive detection of organophosphorus pesticides using a needle type amperometric acetylcholinesterase-based bioelectrode. Thiocholine electrochemistry and immobilised enzyme inhibition. | Journal of enzyme inhibition and medicinal chemistry 20020401 |
Tricyclic cyanoguanidines: synthesis, site of action and insecticidal activity of a novel class of reversible acetylcholinesterase inhibitors. | Bioorganic & medicinal chemistry 20020301 |
Catalytic buffers enable positive-response inhibition-based sensing of nerve agents. | Biotechnology and bioengineering 20020205 |
Serum paraoxonase activity: a new additional test for the improved evaluation of chronic liver damage. | Clinical chemistry 20020201 |
Atorvastatin preferentially reduces LDL-associated platelet-activating factor acetylhydrolase activity in dyslipidemias of type IIA and type IIB. | Arteriosclerosis, thrombosis, and vascular biology 20020201 |
GFP-visualized immobilized enzymes: degradation of paraoxon via organophosphorus hydrolase in a packed column. | Biotechnology and bioengineering 20020120 |
In vitro effects of chlorpyrifos, parathion, methyl parathion and their oxons on cardiac muscarinic receptor binding in neonatal and adult rats. | Toxicology 20020115 |
In vitro effects of organophosphorus anticholinesterases on muscarinic receptor-mediated inhibition of acetylcholine release in rat striatum. | Toxicology and applied pharmacology 20020115 |
Validation of different commercially available cholinesterases for pesticide toxicity test. | Annali di chimica 20020101 |
Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer. | BMC biotechnology 20020101 |
Cerivastatin modulates plasma paraoxonase/arylesterase activity and oxidant-antioxidant balance in the rat. | Polish journal of pharmacology 20020101 |
Species- and substrate-specific stimulation of human plasma paraoxonase 1 (PON1) activity by high chloride concentration. | Acta biochimica Polonica 20020101 |
Effect of some insecticides on acetylcholinesterase from beneficial insects: Coccinella septempunctata, Chrysoperla carnea and Forficula auricularia. | Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 20020101 |
Lipolytic and esterolytic activities in posterior lingual glands of rat: a histochemical study. | The Histochemical journal 20020101 |
Interaction between organophosphorous hydrolase and paraoxon studied by surface chemistry in situ at air-water interface. | Talanta 20011213 |
Development of a quantitative relationship between inhibition percentage and both incubation time and inhibitor concentration for inhibition biosensors--theoretical and practical considerations. | Biosensors & bioelectronics 20011201 |
Simultaneous degradation of organophosphorus pesticides and p-nitrophenol by a genetically engineered Moraxella sp. with surface-expressed organophosphorus hydrolase. | Biotechnology and bioengineering 20011201 |
Organophosphorus compounds alter intracellular F-actin content in SH-SY5Y human neuroblastoma cells. | Neurotoxicology 20011201 |
The active site of human paraoxonase (PON1). | Journal of applied toxicology : JAT 20011201 |
Peripheral site ligands accelerate inhibition of acetylcholinesterase by neutral organophosphates. | Journal of applied toxicology : JAT 20011201 |
Carboxylesterase: specificity and spontaneous reactivation of an endogenous scavenger for organophosphorus compounds. | Journal of applied toxicology : JAT 20011201 |
Interactions of rat brain acetylcholinesterase with the detergent Triton X-100 and the organophosphate paraoxon. | Toxicological sciences : an official journal of the Society of Toxicology 20011001 |
Lipolytic activity of ricin from Ricinus sanguineus and Ricinus communis on neutral lipids. | The Biochemical journal 20010915 |
Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line. | Journal of controlled release : official journal of the Controlled Release Society 20010911 |
A quantitative histochemistry technique for measuring regional distribution of acetylcholinesterase in the brain using digital scanning densitometry. | Analytical biochemistry 20010901 |
Amperometric microbial biosensor for direct determination of organophosphate pesticides using recombinant microorganism with surface expressed organophosphorus hydrolase. | Biosensors & bioelectronics 20010901 |
Paraoxonase status in coronary heart disease: are activity and concentration more important than genotype? | Arteriosclerosis, thrombosis, and vascular biology 20010901 |
Insecticides and atherosclerosis. | Journal of molecular medicine (Berlin, Germany) 20010801 |
Influence of the conformational flexibility on the kinetics and dimerisation process of two Candida rugosa lipase isoenzymes. | FEBS letters 20010713 |
Purification and characterization of carbaryl hydrolase from Arthrobacter sp. RC100. | FEMS microbiology letters 20010710 |
Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population. | Metabolism: clinical and experimental 20010701 |
Resolving pathways of interaction of covalent inhibitors with the active site of acetylcholinesterases: MALDI-TOF/MS analysis of various nerve agent phosphyl adducts. | Chemical research in toxicology 20010701 |
Glucose feeding exacerbates parathion-induced neurotoxicity. | Journal of toxicology and environmental health. Part A 20010622 |
Flow injection amperometric enzyme biosensor for direct determination of organophosphate nerve agents. | Environmental science & technology 20010615 |
Biochemical factors contributing to response variation among resistant and sensitive clones of Daphnia magna Ssraus exposed to ethyl parathion. | Ecotoxicology and environmental safety 20010601 |
The role of glutathione S-transferases in the detoxification of some organophosphorus insecticides in larvae and pupae of the yellow mealworm, Tenebrio molitor (Coleoptera: Tenebrionidae). | Pest management science 20010601 |
Optimisation of FIA system for detection of organophosphorus and carbamate pesticides based on cholinesterase inhibition. | Talanta 20010530 |
Inhibition of calcium-stimulated ATPase in the hen brain P2 synaptosomal fraction by organophosphorus esters: relevance to delayed neuropathy. | Journal of toxicology and environmental health. Part A 20010525 |
Short, strong hydrogen bonds at the active site of human acetylcholinesterase: proton NMR studies. | Biochemistry 20010515 |
Flow-injection spectrophotometric determination of paraoxon by its inhibitory effect on the enzyme acetylcholinesterase. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010501 |
Purification and characterization of trans-permethrin metabolizing microsomal esterases from workers of the eastern subterranean termite, Reticulitermes flavipes (Kollar). | Insect biochemistry and molecular biology 20010427 |
Soluble and membrane-bound acetylcholinesterases in Mytilus galloprovincialis (Pelecypoda: Filibranchia) from the northern Adriatic sea. | Chemico-biological interactions 20010416 |
Capillary electrophoresis microchips for separation and detection of organophosphate nerve agents. | Analytical chemistry 20010415 |
Serum paraoxonase activities in hemodialyzed uremic patients: cohort study. | Croatian medical journal 20010401 |
Decreased stability of the M54 isoform of paraoxonase as a contributory factor to variations in human serum paraoxonase concentrations. | Journal of lipid research 20010401 |
Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. | Arteriosclerosis, thrombosis, and vascular biology 20010401 |
Bioelectrochemical analysis of neuropathy target esterase activity in blood. | Analytical biochemistry 20010301 |
Paraoxonase1-192 polymorphism modulates the nonfatal myocardial infarction risk associated with decreased HDLs. | Arteriosclerosis, thrombosis, and vascular biology 20010301 |
Effects of subchronic parathion exposure on cyclosporine pharmacokinetics in rats. | Journal of toxicology and environmental health. Part A 20010223 |
Mobility of the active site bound paraoxon and sarin in zinc-phosphotriesterase by molecular dynamics simulation and quantum chemical calculation. | Journal of the American Chemical Society 20010207 |
Enhancement, relaxation, and reversal of the stereoselectivity for phosphotriesterase by rational evolution of active site residues. | Biochemistry 20010206 |
Purification and characterization of a phosphoric triester hydrolase from the tufted apple bud moth, Platynota idaeusalis (Walker). | Journal of biochemical and molecular toxicology 20010101 |
Pralidoxime and l-lactate effects in vitro on the inhibition of acetylcholinesterase by paraoxon: pralidoxime does not confer superior protection. | Journal of applied toxicology : JAT 20010101 |
Paraoxon sensitive phenylvalerate hydrolase in assessing the severity of acute paraoxon poisoning. | Journal of toxicology. Clinical toxicology 20010101 |
High-dose intravenous paraoxon exposure does not cause organophosphate-induced delayed neuropathy (OPIDN) in mini pigs. | Journal of applied toxicology : JAT 20010101 |
1H-MRS detected lipolysis in diabetic rat hearts requires neutral lipase. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20010101 |
Esterase inhibition in SH-SY5Y human neuroblastoma cells following exposure to organophosphorus compounds for 28 days. | In vitro & molecular toxicology 20010101 |
Inhibition of forskolin-stimulated cAMP formation in vitro by paraoxon and chlorpyrifos oxon in cortical slices from neonatal, juvenile, and adult rats. | Journal of biochemical and molecular toxicology 20010101 |
Organophosphorus compound-induced apoptosis in SH-SY5Y human neuroblastoma cells. | Toxicology and applied pharmacology 20001015 |
The PON1 gene and detoxication. | Neurotoxicology 20000801 |
[Participation of a distant cholinergic mechanism in the response of the vascular bed to intoxication by organophosphorus inhibitors of cholinesterase]. | Morfologiia (Saint Petersburg, Russia) 20000101 |
Oxime reactivation of RBC acetylcholinesterases for biomonitoring. | Archives of environmental contamination and toxicology 19991001 |
The influence of peripheral site ligands on the reaction of symmetric and chiral organophosphates with wildtype and mutant acetylcholinesterases. | Chemico-biological interactions 19990514 |
Paraoxonase as a risk marker for cardiovascular disease: facts and hypotheses. | Clinical chemistry and laboratory medicine 19980601 |
Inhibition of carboxylesterases in SH-SY5Y human and NB41A3 mouse neuroblastoma cells by organophosphorus esters. | Journal of toxicology and environmental health. Part A 19980313 |
Differential expression of muscarinic subtype mRNAs after exposure to neurotoxic pesticides. | Neurobiology of aging 19980101 |
Site-directed mutagenesis of an acetylcholinesterase gene from the yellow fever mosquito Aedes aegypti confers insecticide insensitivity. | Experimental parasitology 19971101 |
Acetylcholinesterase and neuropathy target esterase inhibitions in neuroblastoma cells to distinguish organophosphorus compounds causing acute and delayed neurotoxicity. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19970701 |
Subacute neurotoxicity induced in mice by potent organophosphorus neuropathy target esterase inhibitors. | Toxicology and applied pharmacology 19960701 |
Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds. | Archives of toxicology 19960101 |
Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase. | Proceedings of the National Academy of Sciences of the United States of America 19940621 |
Carbamate poisoning and oxime treatment in children: a clinical and laboratory study. | Pediatrics 19940401 |
Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected carbamate and organophosphate insecticides and congeners of carbaryl. | Immunopharmacology and immunotoxicology 19930101 |
[Effects of diisopropylfluorophosphate, paraoxon and dichlophos on [3H] quinuclidinyl benzylate binding to the rat striatum synaptic membranes]. | Biulleten' eksperimental'noi biologii i meditsiny 19920901 |
The specificity of carboxylesterase protection against the toxicity of organophosphorus compounds. | Toxicology and applied pharmacology 19920601 |
Age sensitivity to organophosphate-induced delayed polyneuropathy. Biochemical and toxicological studies in developing chicks. | Biochemical pharmacology 19910515 |
Lithium modifies convulsions and brain phosphoinositide turnover induced by organophosphates. | Pharmacology & toxicology 19910501 |
Acetylcholinesterase fiber-optic biosensor for detection of anticholinesterases. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19910501 |
Modulation of the embryotoxicity and cytotoxicity elicited by 7-hydroxy-2-acetylaminofluorene and acetaminophen via deacetylation. | Toxicology and applied pharmacology 19890301 |
Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy. | Journal of neurochemistry 19871101 |
Pesticide induced muscle necrosis: mechanisms and prevention. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19840401 |
Characterization of the serine reacting with diethyl p-nitrophenyl phosphate in porcine pancreatic lipase. | Biochimica et biophysica acta 19810724 |
Central and peripheral neurotoxic esterase activity and dose-response relationship in adult hens after acute and chronic oral administration of diisopropyl fluorophosphate. | Ecotoxicology and environmental safety 19781201 |
Pathways of microbial metabolism of parathion. | Applied and environmental microbiology 19760101 |
Interaction of dichlorvos and anticholinesterases on the in vitro inhibition of human blood cholinesterases. | Toxicology and applied pharmacology 19740201 |
Pseudocholinesterases of mammalian plasma: physicochemical properties and organophosphate inhibition in eleven species. | Toxicology and applied pharmacology 19730101 |