L-Glutamic acid, N-acetyl-L-α-aspartyl-
| Title | Journal |
|---|---|
| Altered development of the dorsolateral prefrontal cortex in chromosome 22q11.2 deletion syndrome: an in vivo proton spectroscopy study. | Biological psychiatry 20121015 |
| NAA and NAAG variation in neuronal activation during visual stimulation. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20121001 |
| Metabolite detection of pancreatic carcinoma by in vivo proton MR spectroscopy at 3T: initial results. | La Radiologia medica 20120801 |
| Three-dimensional arbitrary voxel shapes in spectroscopy with submillisecond TEs. | NMR in biomedicine 20120801 |
| NAAG peptidase inhibitors block cognitive deficit induced by MK-801 and motor activation induced by d-amphetamine in animal models of schizophrenia. | Translational psychiatry 20120701 |
| Effects of N-acetylaspartylglutamate (NAAG) peptidase inhibition on release of glutamate and dopamine in prefrontal cortex and nucleus accumbens in phencyclidine model of schizophrenia. | The Journal of biological chemistry 20120622 |
| Differences in apparent diffusion coefficients of brain metabolites between grey and white matter in the human brain measured at 7 T. | Magnetic resonance in medicine 20120501 |
| Glutamate carboxypeptidase II gene polymorphisms and neural tube defects in a high-risk Chinese population. | Metabolic brain disease 20120301 |
| Proton magnetic resonance spectroscopy and its diagnostically important metabolites in the brain. | General physiology and biophysics 20120301 |
| Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla. | Biological psychiatry 20120201 |
| Increased N-acetylaspartate in model mouse of Pelizaeus-Merzbacher disease. | Journal of magnetic resonance imaging : JMRI 20120201 |
| Effects of bee venom on glutamate-induced toxicity in neuronal and glial cells. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Glutamate carboxypeptidase II in diagnosis and treatment of neurologic disorders and prostate cancer. | Current medicinal chemistry 20120101 |
| Elevated pontine and putamenal GABA levels in mild-moderate Parkinson disease detected by 7 tesla proton MRS. | PloS one 20120101 |
| Tissue distribution of glutamate carboxypeptidase II (GCPII) with a focus on the central and peripheral nervous system. | Current medicinal chemistry 20120101 |
| NAAG, NMDA receptor and psychosis. | Current medicinal chemistry 20120101 |
| Structure-activity relationships of glutamate carboxypeptidase II (GCPII) inhibitors. | Current medicinal chemistry 20120101 |
| Altered neurochemical ingredient of hippocampus in patients with bipolar depression. | Depression research and treatment 20120101 |
| Advances in corticosteroid therapy for ocular inflammation: loteprednol etabonate. | International journal of inflammation 20120101 |
| Adult mouse basal forebrain harbors two distinct cholinergic populations defined by their electrophysiology. | Frontiers in behavioral neuroscience 20120101 |
| Elevated glutamatergic compounds in pregenual anterior cingulate in pediatric autism spectrum disorder demonstrated by 1H MRS and 1H MRSI. | PloS one 20120101 |
| Metabolite profiles correlate closely with neurobehavioral function in experimental spinal cord injury in rats. | PloS one 20120101 |
| N-acetylaspartylglutamate is an agonist at mGluR₃ in vivo and in vitro. | Journal of neurochemistry 20111201 |
| Proton magnetic resonance spectroscopy and thought disorder in childhood schizophrenia. | Schizophrenia research 20111201 |
| N-acetylaspartylglutamate is not demonstrated to be a selective mGlu₃receptor agonist. | Journal of neurochemistry 20111201 |
| A modular strategy to prepare multivalent inhibitors of prostate-specific membrane antigen (PSMA). | Oncotarget 20111201 |
| Molecular identification of β-citrylglutamate hydrolase as glutamate carboxypeptidase 3. | The Journal of biological chemistry 20111104 |
| Whole-exome sequencing detects somatic mutations of IDH1 in metaphyseal chondromatosis with D-2-hydroxyglutaric aciduria (MC-HGA). | American journal of medical genetics. Part A 20111101 |
| Metabolic abnormalities in pain-processing regions of patients with fibromyalgia: a 3T MR spectroscopy study. | AJNR. American journal of neuroradiology 20111001 |
| Who is resilient to depression? Multimodal imaging of the hippocampus in preclinical chronic mild stress model may provide clues. | Biological psychiatry 20110901 |
| Cerebral metabolic alterations and cognitive dysfunction in chronic kidney disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110801 |
| Advances in understanding the peptide neurotransmitter NAAG and appearance of a new member of the NAAG neuropeptide family. | Journal of neurochemistry 20110801 |
| Quantitative measurement of N-acetyl-aspartyl-glutamate at 3 T using TE-averaged PRESS spectroscopy and regularized lineshape deconvolution. | Magnetic resonance in medicine 20110801 |
| Transcranial direct current stimulation (tDCS) produces localized and specific alterations in neurochemistry: a ¹H magnetic resonance spectroscopy study. | Neuroscience letters 20110801 |
| Group II mGluR agonist LY354740 and NAAG peptidase inhibitor effects on prepulse inhibition in PCP and D-amphetamine models of schizophrenia. | Psychopharmacology 20110701 |
| Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans. | PLoS genetics 20110701 |
| Post-injury administration of NAAG peptidase inhibitor prodrug, PGI-02776, in experimental TBI. | Brain research 20110613 |
| Brainstem metabolites in multiple system atrophy of cerebellar type: 3.0-T magnetic resonance spectroscopy study. | Movement disorders : official journal of the Movement Disorder Society 20110601 |
| N-acetylaspartylglutamate synthetase II synthesizes N-acetylaspartylglutamylglutamate. | The Journal of biological chemistry 20110513 |
| Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy. | Gut 20110301 |
| Anterior cingulate and frontal lobe white matter spectroscopy in early childhood of former very LBW premature infants. | Pediatric research 20110301 |
| Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus. | Nutritional neuroscience 20110301 |
| Correlation of findings in advanced MRI techniques with global severity scales in patients with Parkinson disease. | Academic radiology 20110201 |
| 1H-MRS in spinal cord injury: acute and chronic metabolite alterations in rat brain and lumbar spinal cord. | The European journal of neuroscience 20110201 |
| N-acetylaspartylglutamate in CNS hypomyelination. | Neuropediatrics 20110201 |
| Orally active glutamate carboxypeptidase II inhibitor 2-MPPA attenuates dizocilpine-induced prepulse inhibition deficits in mice. | Brain research 20110131 |
| Differential regional N-acetylaspartate deficits in postmortem brain in schizophrenia, bipolar disorder and major depressive disorder. | Journal of psychiatric research 20110101 |
| Discordant behavioral effects of psychotomimetic drugs in mice with altered NMDA receptor function. | Psychopharmacology 20110101 |
| Review: magnetic resonance spectroscopy studies of pediatric major depressive disorder. | Depression research and treatment 20110101 |
| mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists. | Molecular pain 20110101 |
| Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies. | Journal of translational medicine 20110101 |
| Multiple endpoint analysis of BAC-preserved and unpreserved antiallergic eye drops on a 3D-reconstituted corneal epithelial model. | Molecular vision 20110101 |
| MR spectroscopy-based brain metabolite profiling in propionic acidaemia: metabolic changes in the basal ganglia during acute decompensation and effect of liver transplantation. | Orphanet journal of rare diseases 20110101 |
| Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease. | PloS one 20110101 |
| Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer. | PloS one 20110101 |
| Glutathione restores the mechanism of synaptic plasticity in aged mice to that of the adult. | PloS one 20110101 |
| The Vertebrate Brain, Evidence of Its Modular Organization and Operating System: Insights into the Brain's Basic Units of Structure, Function, and Operation and How They Influence Neuronal Signaling and Behavior. | Frontiers in behavioral neuroscience 20110101 |
| Evidence that the tri-cellular metabolism of N-acetylaspartate functions as the brain's 'operating system': how NAA metabolism supports meaningful intercellular frequency-encoded communications. | Amino acids 20101101 |
| Measurement of N-acetylaspartylglutamate in the human frontal brain by 1H-MRS at 7 T. | Magnetic resonance in medicine 20101101 |
| Glutamate carboxypeptidase II: an amyloid peptide-degrading enzyme with physiological function in the brain. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101101 |
| Elevated CSF N-acetylaspartylglutamate suggests specific molecular diagnostic abnormalities in patients with white matter diseases. | Biochimica et biophysica acta 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase. | The Journal of biological chemistry 20100924 |
| Molecular characterization of N-acetylaspartylglutamate synthetase. | The Journal of biological chemistry 20100917 |
| Bioanalysis of N-acetyl-aspartyl-glutamate as a marker of glutamate carboxypeptidase II inhibition. | Analytical biochemistry 20100901 |
| Proton magnetic resonance spectroscopy of brain in obstructive sleep apnoea in north Indian Asian subjects. | The Indian journal of medical research 20100901 |
| Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia. | Dialogues in clinical neuroscience 20100901 |
| Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status. | Movement disorders : official journal of the Movement Disorder Society 20100715 |
| Riluzole decreases synthesis of N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells. | Brain research 20100602 |
| Determination of kynurenic acid levels in rat brain microdialysis samples and changes in kynurenic acid levels induced by N-acetylaspartic acid. | Biomedical chromatography : BMC 20100601 |
| Glutamate carboxypeptidase inhibition reduces the severity of chemotherapy-induced peripheral neurotoxicity in rat. | Neurotoxicity research 20100501 |
| Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats. | European journal of pharmacology 20100210 |
| Elevated CSF N-acetylaspartylglutamate in patients with free sialic acid storage diseases. | Neurology 20100126 |
| A novel key-lock mechanism for inactivating amino acid neurotransmitters during transit across extracellular space. | Amino acids 20100101 |
| N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats. | Neuropharmacology 20100101 |
| Metabolic changes in rat brain following intracerebroventricular injections of streptozotocin: a model of sporadic Alzheimer's disease. | Acta neurochirurgica. Supplement 20100101 |
| Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. | Journal of neurochemistry 20100101 |
| Pain perception in neurodevelopmental animal models of schizophrenia. | Physiological research 20100101 |
| Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS. | PloS one 20100101 |
| Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate. | Arthritis research & therapy 20100101 |
| Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model. | Molecular pain 20100101 |
| Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patients. | Journal of affective disorders 20091201 |
| MR spectroscopic evaluation of N-acetylaspartate's T2 relaxation time and concentration corroborates white matter abnormalities in schizophrenia. | NeuroImage 20091115 |
| Unraveling pathology in juvenile Alexander disease: serial quantitative MR imaging and spectroscopy of white matter. | Neuroradiology 20091001 |
| Are astrocytes the missing link between lack of brain aspartoacylase activity and the spongiform leukodystrophy in Canavan disease? | Neurochemical research 20090901 |
| GCP II inhibition rescues neurons from gp120IIIB-induced neurotoxicity. | Journal of neurovirology 20090901 |
| The neuroactive peptide N-acetylaspartylglutamate is not an agonist at the metabotropic glutamate receptor subtype 3 of metabotropic glutamate receptor. | The Journal of pharmacology and experimental therapeutics 20090701 |
| Differential expression of metabotropic glutamate receptors 2 and 3 in schizophrenia: a mechanism for antipsychotic drug action? | The American journal of psychiatry 20090701 |
| Intracerebroventricular administration of N-acetylaspartic acid impairs antioxidant defenses and promotes protein oxidation in cerebral cortex of rats. | Metabolic brain disease 20090601 |
| The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes. | Brain : a journal of neurology 20090601 |
| Reaction mechanism of glutamate carboxypeptidase II revealed by mutagenesis, X-ray crystallography, and computational methods. | Biochemistry 20090519 |
| Distinct MRI pattern in lesional and perilesional area after traumatic brain injury in rat--11 months follow-up. | Experimental neurology 20090101 |
| Role of retinal glial cells in neurotransmitter uptake and metabolism. | Neurochemistry international 20090101 |
| Effects of N-acetylaspartylglutamate (NAAG) at group II mGluRs and NMDAR. | Neuropharmacology 20090101 |
| In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment. | BMC neuroscience 20090101 |
| In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain. | BMC neuroscience 20090101 |
| Excitatory neurotransmitters in brain regions in interictal migraine patients. | Molecular pain 20090101 |
| Linking mechanistic and behavioral responses to sublethal esfenvalerate exposure in the endangered delta smelt; Hypomesus transpacificus (Fam. Osmeridae). | BMC genomics 20090101 |
| Development and application of a liquid chromatography/tandem mass spectrometric assay for measurement of N-acetylaspartate, N-acetylaspartylglutamate and glutamate in brain slice superfusates and tissue extracts. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081215 |
| [Intra-annual and seasonal allergic conjunctivitis treatment: comparison of two therapeutic protocols]. | Journal francais d'ophtalmologie 20081201 |
| Simultaneous determination of N-acetylaspartylglutamate and N-acetylaspartate in rat brain homogenate using high-performance liquid chromatography with pre-column fluorescence derivatization. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115 |
| Proton magnetic resonance spectroscopy reveals medial temporal metabolic abnormalities in adolescents with history of preterm birth. | Pediatric research 20081101 |
| The effect of epileptic seizures on proton MRS visible neurochemical concentrations. | Epilepsy research 20080901 |
| Modeling the impact of COPD on the brain. | International journal of chronic obstructive pulmonary disease 20080901 |
| Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease. | Journal of neurology, neurosurgery, and psychiatry 20080801 |
| Reduced parietooccipital white matter glutamine measured by proton magnetic resonance spectroscopy in treated graves' disease patients. | The Journal of clinical endocrinology and metabolism 20080801 |
| Antipsychotic drugs increase N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells. | Journal of neurochemistry 20080801 |
| Increased level of N-acetylaspartylglutamate (NAAG) in the CSF of a patient with Pelizaeus-Merzbacher-like disease due to mutation in the GJA12 gene. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20080701 |
| The astrocyte surface NAAG receptor and NAAG peptidase signaling complex as a therapeutic target. | Drug news & perspectives 20080601 |
| Comparative efficacy of topical antihistamines in an animal model of early phase allergic conjunctivitis. | Experimental eye research 20080501 |
| Cerebral impairment in chronic solvent-induced encephalopathy. | Annals of neurology 20080501 |
| N-acetylaspartate and N-acetylaspartylglutamate: neurobiology and clinical significance. | Neurology 20080415 |
| Small-molecule complement inhibitors cannot prevent the development of the platelet storage lesion. | Transfusion 20080401 |
| N-acetyl-L-aspartate activates hippocampal CA3 neurons in rodent slice preparations. | Brain research bulletin 20080328 |
| Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs. | Journal of molecular biology 20080307 |
| Oxidative stress and protein oxidation in the brain of water drinking and alcohol drinking rats administered the HIV envelope protein, gp120. | Journal of neurochemistry 20080301 |
| Regional apparent metabolite concentrations in young adult brain measured by (1)H MR spectroscopy at 3 Tesla. | Journal of magnetic resonance imaging : JMRI 20080301 |
| Effects of selective inhibition of N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) on mice in learning and memory tasks. | European journal of pharmacology 20080128 |
| Phencyclidine and dizocilpine induced behaviors reduced by N-acetylaspartylglutamate peptidase inhibition via metabotropic glutamate receptors. | Biological psychiatry 20080101 |
| Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain. | Molecular pain 20080101 |
| Neurobiology of spirituality. | Mens sana monographs 20080101 |
| Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain. | Journal of magnetic resonance imaging : JMRI 20071201 |
| Assessment of metabolite quantitation reproducibility in serial 3D-(1)H-MR spectroscopic imaging of human brain using stereotactic repositioning. | Magnetic resonance in medicine 20071001 |
| Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis. | The FEBS journal 20070901 |
| Using proton magnetic resonance imaging and spectroscopy to understand brain 'activation'. | Brain and language 20070801 |
| Low choline concentrations in normal-appearing white matter of patients with multiple sclerosis and normal MR imaging brain scans. | AJNR. American journal of neuroradiology 20070801 |
| Temporal window of metabolic brain vulnerability to concussions: mitochondrial-related impairment--part I. | Neurosurgery 20070801 |
| Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II. | Journal of medicinal chemistry 20070712 |
| Quantitative proton MRS of cerebral metabolites in laminin alpha2 chain deficiency. | Brain & development 20070701 |
| Different transfer of nociceptive sensitivity from rats with postnatal hippocampal lesions to control rats. | The European journal of neuroscience 20070701 |
| In vivo differentiation of N-acetyl aspartyl glutamate from N-acetyl aspartate at 3 Tesla. | Magnetic resonance in medicine 20070601 |
| Group II metabotropic glutamate receptors inhibit glutamate release at thalamocortical synapses in the developing somatosensory cortex. | Neuroscience 20070525 |
| Selective vulnerability of hippocampal NAAGergic neurons in experimental temporal lobe epilepsy. | Brain research 20070504 |
| Biochemical characterization of human glutamate carboxypeptidase III. | Journal of neurochemistry 20070501 |
| The effect of sodium valproate on proton MRS visible neurochemical concentrations. | Epilepsy research 20070501 |
| Carbamazepine treatment recovered low N-acetylaspartate+N-acetylaspartylglutamate (tNAA) levels in the megencephaly mouse BALB/cByJ-Kv1.1(mceph/mceph). | Neurobiology of disease 20070401 |
| Expression of glutamate carboxypeptidase II in human brain. | Neuroscience 20070223 |
| 1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG. | Epilepsia 20070201 |
| Modeling of context-dependent retrieval in hippocampal region CA1: implications for cognitive function in schizophrenia. | Schizophrenia research 20070101 |
| Endogenous N-acetylaspartylglutamate reduced NMDA receptor-dependent current neurotransmission in the CA1 area of the hippocampus. | Journal of neurochemistry 20070101 |
| Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats. | The European journal of neuroscience 20070101 |
| Clinical and biological efficacy of preservative-free NAAGA eye-drops versus levocabastine eye-drops in vernal keratoconjunctivitis patients. | The British journal of ophthalmology 20070101 |
| 2-5A ligands--a new concept for the treatment of prostate cancer. | Nucleosides, nucleotides & nucleic acids 20070101 |
| Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain - relation to brain concentration. | Neuropharmacology 20061201 |
| Modulation of GABAergic inhibition in the rat superior colliculus by a presynaptic group II metabotropic glutamate receptor. | The Journal of physiology 20061201 |
| Cerebral metabolic and structural alterations in hereditary spastic paraplegia with thin corpus callosum assessed by MRS and DTI. | Neuroradiology 20061201 |
| Effect of dipeptide N-acetylaspartylglutamate on denervation-induced changes in the volume of rat skeletal muscle fibers. | Bulletin of experimental biology and medicine 20061201 |
| Metabolic analysis of mouse brains that have compromised iron storage. | Metabolic brain disease 20060901 |
| [Alteration of the antinociceptive systems in chronic daily headaches]. | Revista de neurologia 20060901 |
| Regulation of N-acetylaspartate and N-acetylaspartylglutamate biosynthesis by protein kinase activators. | Journal of neurochemistry 20060901 |
| Ketamine and N-acetylaspartylglutamate peptidase inhibitor exert analgesia in bone cancer pain. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060901 |
| Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing? | Archives of neurology 20060801 |
| Detection of cerebral degeneration in amyotrophic lateral sclerosis using high-field magnetic resonance spectroscopy. | Archives of neurology 20060801 |
| Natural history of Canavan disease revealed by proton magnetic resonance spectroscopy (1H-MRS) and diffusion-weighted MRI. | Neuropediatrics 20060801 |
| NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat. | Journal of neurochemistry 20060501 |
| Identifying the affected hemisphere by (1)H-MR spectroscopy in patients with temporal lobe epilepsy and no pathological findings in high resolution MRI. | European journal of neurology 20060501 |
| ProFit: two-dimensional prior-knowledge fitting of J-resolved spectra. | NMR in biomedicine 20060401 |
| NAAG peptidase as a therapeutic target: Potential for regulating the link between glucose metabolism and cognition. | Drug news & perspectives 20060401 |
| Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer. | The EMBO journal 20060322 |
| Metabolite changes in early relapsing-remitting multiple sclerosis. A two year follow-up study. | Journal of neurology 20060201 |
| Differential negative coupling of type 3 metabotropic glutamate receptor to cyclic GMP levels in neurons and astrocytes. | Journal of neurochemistry 20060201 |
| Neuroprotective effects of selective group II mGluR activation in brain trauma and traumatic neuronal injury. | Journal of neurotrauma 20060201 |
| Magnetic resonance imaging and proton magnetic resonance spectroscopy of megalencephaly and dilated Virchow-Robin spaces. | Pediatric neurology 20060101 |
| Neurotransmitters of the suprachiasmatic nuclei. | Journal of circadian rhythms 20060101 |
| Neonatal administration of N-acetyl-L-aspartyl-L-glutamate induces early neurodegeneration in hippocampus and alters behaviour in young adult rats. | Neurochemistry international 20060101 |
| Preface: a brief review of N-acetylaspartate. | Advances in experimental medicine and biology 20060101 |
| A brief overview of N-acetylaspartate and N-acetylaspartylglutamate. | Advances in experimental medicine and biology 20060101 |
| Expression of N-acetylaspartate and N-acetylaspartylglutamate in the nervous system. | Advances in experimental medicine and biology 20060101 |
| Canavan disease: studies on the knockout mouse. | Advances in experimental medicine and biology 20060101 |
| Functions of N-acetylaspartate and N-acetylaspartylglutamate in brain: evidence of a role in maintenance of higher brain integrative activities of information processing and cognition. | Advances in experimental medicine and biology 20060101 |
| Hypoacetylaspartia: clinical and biochemical follow-up of a patient. | Advances in experimental medicine and biology 20060101 |
| Synthesis of N-acetylaspartyl-glutamate (NAAG) and N-acetylaspartate (NAA) in axons and glia of the crayfish medial giant nerve fiber. | Advances in experimental medicine and biology 20060101 |
| Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy. | Advances in experimental medicine and biology 20060101 |
| N-acetylaspartylglutamate (NAAG) in spinal cord injury and disease. | Advances in experimental medicine and biology 20060101 |
| N-acetylaspartylglutamate (NAAG) in Pelizaeus-Merzbacher disease. | Advances in experimental medicine and biology 20060101 |
| Neuroprotective effect of N-acetyl-aspartyl-glutamate in combination with mild hypothermia in the endothelin-1 rat model of focal cerebral ischaemia. | Journal of neurochemistry 20051201 |
| Optimized diffusion-weighted spectroscopy for measuring brain glutamate apparent diffusion coefficient on a whole-body MR system. | NMR in biomedicine 20051201 |
| NAAG peptidase inhibitors and their potential for diagnosis and therapy. | Nature reviews. Drug discovery 20051201 |
| Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism. | Clinical biochemistry 20051101 |
| Glutamate carboxypeptidase II levels in rodent brain using [125I]DCIT quantitative autoradiography. | Neuroscience letters 20051028 |
| Mice lacking glutamate carboxypeptidase II are protected from peripheral neuropathy and ischemic brain injury. | Journal of neurochemistry 20051001 |
| A phase rotation scheme for achieving very short echo times with localized stimulated echo spectroscopy. | Magnetic resonance imaging 20051001 |
| Quantitative proton MRS of Pelizaeus-Merzbacher disease: evidence of dys- and hypomyelination. | Neurology 20050913 |
| The metabotropic glutamate receptor mGluR3 is critically required for hippocampal long-term depression and modulates long-term potentiation in the dentate gyrus of freely moving rats. | Cerebral cortex (New York, N.Y. : 1991) 20050901 |
| The neurotransmitter N-acetylaspartylglutamate in models of pain, ALS, diabetic neuropathy, CNS injury and schizophrenia. | Trends in pharmacological sciences 20050901 |
| Central N-acetyl aspartylglutamate deficit: a possible pathogenesis of schizophrenia. | Medical science monitor : international medical journal of experimental and clinical research 20050901 |
| Glycyl-L-glutamine disposition in rat choroid plexus epithelial cells in primary culture: role of PEPT2. | Pharmaceutical research 20050801 |
| Strategies to increase central N-acetyl aspartylglutamate: a potential treatment for schizophrenia and bipolar disorders. | Schizophrenia research 20050715 |
| Effect of N-acetylaspartylglutamate (NAAG) on non-quantal and spontaneous quantal release of acetylcholine at the neuromuscular synapse of rat. | Journal of neurochemistry 20050701 |
| Regulation of glutamate carboxypeptidase II hydrolysis of N-acetylaspartylglutamate (NAAG) in crayfish nervous tissue is mediated by glial glutamate and acetylcholine receptors. | Journal of neurochemistry 20050501 |
| Metabolic characterization of distinct neuroanatomical regions in rats by magic angle spinning 1H nuclear magnetic resonance spectroscopy. | Magnetic resonance in medicine 20050501 |
| Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050316 |
| Chronic phencyclidine administration induces schizophrenia-like changes in N-acetylaspartate and N-acetylaspartylglutamate in rat brain. | Schizophrenia research 20050301 |
| In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats. | Journal of neurochemistry 20050301 |
| NAAG reduces NMDA receptor current in CA1 hippocampal pyramidal neurons of acute slices and dissociated neurons. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050101 |
| Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis. | Neuropharmacology 20050101 |
| High-field localized 1H NMR spectroscopy in the anesthetized and in the awake monkey. | Magnetic resonance imaging 20041201 |
| In vivo quantitative 1H MRS of cerebellum and evaluation of quantitation reproducibility by simulation of different levels of noise and spectral resolution. | Magnetic resonance imaging 20041201 |
| Serotonin1B receptors: from protein to physiological function and behavior. | Neuroscience and biobehavioral reviews 20041001 |
| Quantitative 1H-MRS of healthy human cortex, hippocampus, and thalamus: metabolite concentrations, quantification precision, and reproducibility. | Journal of magnetic resonance imaging : JMRI 20040901 |
| Clinical correlation of brain MRI and MRS abnormalities in patients with Wilson disease. | Neurology 20040824 |
| Aspartoacylase deficiency does not affect N-acetylaspartylglutamate level or glutamate carboxypeptidase II activity in the knockout mouse brain. | Brain research 20040806 |
| Biosynthesis of NAAG by an enzyme-mediated process in rat central nervous system neurons and glia. | Journal of neurochemistry 20040801 |
| Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model. | The European journal of neuroscience 20040701 |
| Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity. | Protein science : a publication of the Protein Society 20040601 |
| SH-SY5Y neuroblastoma cells: a model system for studying biosynthesis of NAAG. | Neuroreport 20040519 |
| Severe hypomyelination associated with increased levels of N-acetylaspartylglutamate in CSF. | Neurology 20040511 |
| The cloning and characterization of a second brain enzyme with NAAG peptidase activity. | Journal of neurochemistry 20040501 |
| A comparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brain. | Magnetic resonance imaging 20040501 |
| NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR. | Journal of neurochemistry 20040501 |
| Protection against glucose-induced neuronal death by NAAG and GCP II inhibition is regulated by mGluR3. | Journal of neurochemistry 20040401 |
| Synthesis of urea-based inhibitors as active site probes of glutamate carboxypeptidase II: efficacy as analgesic agents. | Journal of medicinal chemistry 20040325 |
| NAAG fails to antagonize synaptic and extrasynaptic NMDA receptors in cerebellar granule neurons. | Neuropharmacology 20040301 |
| Measurement of brain glutamate using TE-averaged PRESS at 3T. | Magnetic resonance in medicine 20040301 |
| Tumor target prostate specific membrane antigen (PSMA) and its regulation in prostate cancer. | Journal of cellular biochemistry 20040215 |
| Reduced isolation-induced aggressiveness in mice following NAALADase inhibition. | Psychopharmacology 20040201 |
| GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism. | Journal of neurophysiology 20040101 |
| Glutamate carboxypeptidase II gene expression in the human frontal and temporal lobe in schizophrenia. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040101 |
| Early embryonic death of glutamate carboxypeptidase II (NAALADase) homozygous mutants. | Synapse (New York, N.Y.) 20031215 |
| N-acetylaspartylglutamate and beta-NAAG protect against injury induced by NMDA and hypoxia in primary spinal cord cultures. | Brain research 20031121 |
| Magnetization transfer imaging and magnetic resonance spectroscopy of normal-appearing white matter in late-life major depression. | Journal of magnetic resonance imaging : JMRI 20031101 |
| Metabotropic glutamate receptor regulation of neuronal cell death. | Experimental neurology 20031101 |
| High-field proton MRS of human brain. | European journal of radiology 20031101 |
| Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy. | Neurology 20031014 |
| Effect of carbohydrate moieties on the folate hydrolysis activity of the prostate specific membrane antigen. | The Prostate 20031001 |
| Effects of GCP-II inhibition on responses of dorsal horn neurones after inflammation and neuropathy: an electrophysiological study in the rat. | Neuropeptides 20031001 |
| Expression of glutamate transporter, GABRA6, serine proteinase inhibitor 2 and low levels of glutamate and GABA in the brain of knock-out mouse for Canavan disease. | Brain research bulletin 20030830 |
| Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy. | Psychiatry research 20030730 |
| Prostate targeting ligands based on N-acetylated alpha-linked acidic dipeptidase. | Biochemical and biophysical research communications 20030718 |
| Regulation of glutamate carboxypeptidase II function in corticolimbic regions of rat brain by phencyclidine, haloperidol, and clozapine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701 |
| N-acetylaspartate and N-Acetylaspartylglutamate deficits in superior temporal cortex in schizophrenia and bipolar disorder: a postmortem study. | Biological psychiatry 20030615 |
| Reductions in N-acetylaspartylglutamate and the 67 kDa form of glutamic acid decarboxylase immunoreactivities in the visual system of albino and pigmented rats after optic nerve transections. | The Journal of comparative neurology 20030407 |
| [In vitro effects of antiallergic eyedrops on complement activation induced by particulate matter]. | Journal francais d'ophtalmologie 20030401 |
| Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease. | Neurology 20030311 |
| Characterisation of the 1H and 13C NMR spectra of N-acetylaspartylglutamate and its detection in urine from patients with Canavan disease. | Journal of pharmaceutical and biomedical analysis 20030310 |
| Modulation of epileptiform burst frequency by the metabotropic glutamate receptor subtype mGluR3. | Epilepsy research 20030301 |
| Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging. | NMR in biomedicine 20030201 |
| Cerebral proton magnetic resonance spectroscopy of a patient with giant axonal neuropathy. | Brain & development 20030101 |
| Morphology and ultrastructure of rat hippocampal formation after i.c.v. administration of N-acetyl-L-aspartyl-L-glutamate. | Neuroscience 20030101 |
| Group II and III metabotropic glutamate receptors and the control of the nucleus reticularis thalami input to rat thalamocortical neurones in vitro. | Neuroscience 20030101 |
| Brain metabolite composition during early human brain development as measured by quantitative in vivo 1H magnetic resonance spectroscopy. | Magnetic resonance in medicine 20021201 |
| [N acetyl-aspartyl glutamic acid (NAAGA) inhibits the adhesion of leukocytes to activated endothelial cells and down-modulates the cytokine-induced expression of adhesion molecules]. | Journal francais d'ophtalmologie 20021201 |
| Kinetics and inhibition of glutamate carboxypeptidase II using a microplate assay. | Analytical biochemistry 20021101 |
| High-performance liquid chromatography method for detecting prostate-specific membrane antigen activity. | Analytical biochemistry 20021101 |
| Brain metabolite changes in cortical grey and normal-appearing white matter in clinically early relapsing-remitting multiple sclerosis. | Brain : a journal of neurology 20021001 |
| Maturation of the human fetal brain as observed by 1H MR spectroscopy. | Magnetic resonance in medicine 20021001 |
| Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate. | Journal of neurochemistry 20021001 |
| Glutamine uptake and metabolism to N-acetylaspartylglutamate (NAAG) by crayfish axons and glia. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20021001 |
| Molecular modeling of the interactions of glutamate carboxypeptidase II with its potent NAAG-based inhibitors. | Journal of medicinal chemistry 20020912 |
| A short-echo-time proton magnetic resonance spectroscopic imaging study of temporal lobe epilepsy. | Epilepsia 20020901 |
| NAALADase (GCP II) inhibition prevents cocaine-kindled seizures. | Neuropharmacology 20020901 |
| Mechanism of NMDA receptor contribution to axon-to-glia signaling in the crayfish medial giant nerve fiber. | Glia 20020401 |
| Neuroprotective effects of N-acetylaspartylglutamate in a neonatal rat model of hypoxia-ischemia. | European journal of pharmacology 20020222 |
| Effect of 2-(phosphono-methyl)-pentanedioic acid on allodynia and afferent ectopic discharges in a rat model of neuropathic pain. | The Journal of pharmacology and experimental therapeutics 20020201 |
| Reproducibility of in vivo metabolite quantification with proton magnetic resonance spectroscopic imaging. | Journal of magnetic resonance imaging : JMRI 20020201 |
| Measurement of glutamate carboxypeptidase II (NAALADase) enzyme activity by the hydrolysis of [³H]-N-acetylaspartylglutamate (NAAG). | Current protocols in pharmacology 20020201 |
| N-Acetyl-L-aspartyl-L-glutamate changes functional and structural properties of rat blood-brain barrier. | Neuroscience letters 20020111 |
| Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens. | The Journal of pharmacology and experimental therapeutics 20020101 |
| N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve. | Annals of neurology 20020101 |
| Differential expression of carnosine, homocarnosine and N-acetyl-L-histidine hydrolytic activities in cultured rat macroglial cells. | Journal of molecular neuroscience : MN 20011201 |
| Neuroprotection mediated by glutamate carboxypeptidase II (NAALADase) inhibition requires TGF-beta. | European journal of pharmacology 20011026 |
| Neuroprotection afforded by NAAG and NAALADase inhibition requires glial cells and metabotropic glutamate receptor activation. | European journal of pharmacology 20010824 |
| Spinal N-acetyl-alpha-linked acidic dipeptidase (NAALADase) inhibition attenuates mechanical allodynia induced by paw carrageenan injection in the rat. | Brain research 20010803 |
| In vivo short echo time 1H-magnetic resonance spectroscopic imaging (MRSI) of the temporal lobes. | NeuroImage 20010801 |
| Design of NAALADase inhibitors: a novel neuroprotective strategy. | Current medicinal chemistry 20010701 |
| Group II mGlu receptor agonists fail to protect against various neurotoxic insults induced in murine cortical, striatal and cerebellar granular pure neuronal cultures. | Neuropharmacology 20010701 |
| Postmortem degradation of N-acetyl aspartate and N-acetyl aspartylglutamate: an HPLC analysis of different rat CNS regions. | Neurochemical research 20010601 |
| Absence of N-acetylaspartate in the human brain: impact on neurospectroscopy? | Annals of neurology 20010401 |
| [Synthesis and release of N-acetylaspartyl glutamate (NAAG) in medial giant axons in crayfish]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010401 |
| beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor. | Journal of neurophysiology 20010301 |
| Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy. | Brain : a journal of neurology 20010201 |
| [Antioxidant effects of mast cell inhibitors in a human conjunctival cell line]. | Journal francais d'ophtalmologie 20010201 |
| Amino acids are still as exciting as ever. | Current opinion in pharmacology 20010201 |
| Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain. | Neurochemistry international 20010101 |
| Inhibition of spinal N-acetylated-alpha-linked acidic dipeptidase produces an antinociceptive effect in the rat formalin test. | Neuroscience 20010101 |
| NAAG inhibits KCl-induced [(3)H]-GABA release via mGluR3, cAMP, PKA and L-type calcium conductance. | The European journal of neuroscience 20010101 |
| N-acetylaspartylglutamate (NAAG) is the probable mediator of axon-to-glia signaling in the crayfish medial giant nerve fiber. | Neuroscience 20010101 |
| Synthesis and release of N-acetylaspartylglutamate (NAAG) by crayfish nerve fibers: implications for axon-glia signaling. | Neuroscience 20010101 |
| Mechanisms for clearance of released N-acetylaspartylglutamate in crayfish nerve fibers: implications for axon-glia signaling. | Neuroscience 20010101 |
| Characterization of [(3)H]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using semliki forest virus vectors. | Neuropharmacology 20000724 |