2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole
| Title | Journal |
|---|---|
| Might the observed α(2A)-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? | Bioorganic & medicinal chemistry 20120315 |
| Noradrenergic α₁ receptor antagonist treatment attenuates positive subjective effects of cocaine in humans: a randomized trial. | PloS one 20120101 |
| Yohimbine-induced amygdala activation in pathological gamblers: a pilot study. | PloS one 20120101 |
| Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds. | Journal of neurosciences in rural practice 20120101 |
| Acupuncture for the treatment of opiate addiction. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Exercise and physical activity in the therapy of substance use disorders. | TheScientificWorldJournal 20120101 |
| Tryptophan in alcoholism treatment II: inhibition of the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevation of blood acetaldehyde concentration and induction of aversion to alcohol by combined administration of tryptophan and benserazide. | Alcohol and alcoholism (Oxford, Oxfordshire) 20111101 |
| The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of substance use and related disorders. Part 2: Opioid dependence. | The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20110401 |
| Electroacupuncture treatment normalized sleep disturbance in morphine withdrawal rats. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Outpatient versus inpatient opioid detoxification: a randomized controlled trial. | Journal of substance abuse treatment 20110101 |
| Opioid dependence. | BMJ clinical evidence 20110101 |
| The pharmacological treatment of opioid addiction--a clinical perspective. | European journal of clinical pharmacology 20100601 |
| A comparison of methadone, buprenorphine and alpha(2) adrenergic agonists for opioid detoxification: a mixed treatment comparison meta-analysis. | Drug and alcohol dependence 20100401 |
| Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. | The Annals of pharmacotherapy 20100201 |
| A case report of inpatient detoxification after kratom (Mitragyna speciosa) dependence. | European addiction research 20100101 |
| Clonidine in adults as a sedative agent in the intensive care unit. | Journal of anaesthesiology, clinical pharmacology 20100101 |
| Opioid antagonists with minimal sedation for opioid withdrawal. | The Cochrane database of systematic reviews 20091007 |
| A double-blind, randomized, parallel group study to compare the efficacy, safety and tolerability of slow-release oral morphine versus methadone in opioid-dependent in-patients willing to undergo detoxification. | Addiction (Abingdon, England) 20090901 |
| Alpha2-receptor agonists for treatment and prevention of iatrogenic opioid abstinence syndrome in critically ill patients. | The Annals of pharmacotherapy 20090901 |
| Buprenorphine for the management of opioid withdrawal. | The Cochrane database of systematic reviews 20090708 |
| Electrocardiographic effects of lofexidine and methadone coadministration: secondary findings from a safety study. | Pharmacotherapy 20090501 |
| Alpha2-adrenergic agonists for the management of opioid withdrawal. | The Cochrane database of systematic reviews 20090415 |
| Norepinephrine and stimulant addiction. | Addiction biology 20090401 |
| Pharmacokinetics of lofexidine hydrochloride in healthy volunteers. | Journal of pharmaceutical sciences 20090101 |
| The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) prisons project: a randomised controlled trial comparing dihydrocodeine and buprenorphine for opiate detoxification. | Substance abuse treatment, prevention, and policy 20090101 |
| Pharmacotherapy for cannabis dependence: how close are we? | CNS drugs 20090101 |
| The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) Prisons Project Study: protocol for a randomised controlled trial comparing methadone and buprenorphine for opiate detoxification. | Trials 20090101 |
| Urine and plasma pharmacokinetics of lofexidine after oral delivery in opiate-dependent patients. | The American journal of drug and alcohol abuse 20090101 |
| A study on Fu-Yuan Pellet, a traditional chinese medicine formula for detoxification of heroin addictions. | The American journal of drug and alcohol abuse 20090101 |
| Opioid dependence. | BMJ clinical evidence 20090101 |
| A Phase 3 placebo-controlled, double-blind, multi-site trial of the alpha-2-adrenergic agonist, lofexidine, for opioid withdrawal. | Drug and alcohol dependence 20080901 |
| Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans. | Current neuropharmacology 20080901 |
| Effects of THC and lofexidine in a human laboratory model of marijuana withdrawal and relapse. | Psychopharmacology 20080301 |
| Tai-Kang-Ning, a Chinese herbal medicine formula, alleviates acute heroin withdrawal. | The American journal of drug and alcohol abuse 20080101 |
| Clinical pharmacokinetics of lofexidine, the alpha 2-adrenergic receptor agonist, in opiate addicts plasma using a highly sensitive liquid chromatography tandem mass spectrometric analysis. | The American journal of drug and alcohol abuse 20080101 |
| A comparative clinical study of the effects of the traditional Chinese medicine Jinniu capsules and lofexidine on acute heroin withdrawal symptoms. | The American journal of drug and alcohol abuse 20080101 |
| Agenda for specialty section in addiction medicine. | Indian journal of psychiatry 20080101 |
| Pharmacologic treatments for opioid dependence: detoxification and maintenance options. | Dialogues in clinical neuroscience 20071201 |
| Hemodynamic and cognitive effects of lofexidine and methadone coadministration: a pilot study. | Pharmacotherapy 20070801 |
| Opioid dependence. | BMJ clinical evidence 20070601 |
| In-patient detoxification procedures, treatment retention, and post-treatment opiate use: comparison of lofexidine + naloxone, lofexidine + placebo, and methadone. | Drug and alcohol dependence 20070417 |
| Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings. | Psychopharmacology 20070301 |
| Buprenorphine versus dihydrocodeine for opiate detoxification in primary care: a randomised controlled trial. | BMC family practice 20070101 |
| The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) prisons project pilot study: protocol for a randomised controlled trial comparing dihydrocodeine and buprenorphine for opiate detoxification. | Trials 20070101 |
| The place of detoxification in treatment of opioid dependence. | Current opinion in psychiatry 20060501 |
| Opiate addiction in China: current situation and treatments. | Addiction (Abingdon, England) 20060501 |
| Opioid antagonists with minimal sedation for opioid withdrawal. | The Cochrane database of systematic reviews 20060125 |
| Cognitive function during early abstinence from opioid dependence: a comparison to age, gender, and verbal intelligence matched controls. | BMC psychiatry 20060101 |
| A comparison of buprenorphine and lofexidine for community opiate detoxification: results from a randomized controlled trial. | Addiction (Abingdon, England) 20051201 |
| Is clonidine useful for treatment of clozapine-induced sialorrhea? | Journal of psychopharmacology (Oxford, England) 20050701 |
| Induction of patients with moderately severe methadone dependence onto buprenorphine. | Addiction biology 20050601 |
| Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats. | Psychopharmacology 20050501 |
| Lofexidine for opioid detoxification. | Psychiatry (Edgmont (Pa. : Township)) 20050101 |
| QT interval increased after single dose of lofexidine. | BMJ (Clinical research ed.) 20041106 |
| Evidence-based addiction medicine: the use of lofexidine for opioid detoxification. | Psychiatry (Edgmont (Pa. : Township)) 20041101 |
| Alpha2 adrenergic agonists for the management of opioid withdrawal. | The Cochrane database of systematic reviews 20041018 |
| A placebo-controlled study of lofexidine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. | Journal of psychopharmacology (Oxford, England) 20040601 |
| [Clinical observation on effect of modified banxia houpu decoction in treating patients with protracted heroin abstinence syndrome]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040301 |
| The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: an open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCTN07752728]. | BMC family practice 20040101 |
| Evaluation of the effects of lofexidine and clonidine on naloxone-precipitated withdrawal in opioid-dependent humans. | Addiction (Abingdon, England) 20030401 |
| A placebo-controlled study of lofexidine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. | Journal of psychopharmacology (Oxford, England) 20030301 |
| Major disruptions of sleep during treatment of the opiate withdrawal syndrome: differences between methadone and lofexidine detoxification treatments. | Addiction biology 20030301 |
| Alpha2 adrenergic agonists for the management of opioid withdrawal. | The Cochrane database of systematic reviews 20030101 |
| The effectiveness of combined naloxone/lofexidine in opiate detoxification: results from a double-blind randomized and placebo-controlled trial. | The American journal on addictions 20030101 |
| Lofexidine in hyperactive and impulsive children with autistic disorder. | Journal of the American Academy of Child and Adolescent Psychiatry 20021201 |
| A review of chemical agents in the pharmacotherapy of addiction. | Current medicinal chemistry 20021001 |
| [125I]2-(2-chloro-4-iodo-phenylamino)-5-methyl-pyrroline (LNP 911), a high-affinity radioligand selective for I1 imidazoline receptors. | Molecular pharmacology 20020701 |
| Prison based detoxification for opioid dependence: a randomised double blind controlled trial of lofexidine and methadone. | Drug and alcohol dependence 20020701 |
| Prescribing to drug misusers in practice--often effective, but rarely straightforward. | Addiction biology 20020701 |
| Use of qigong therapy in the detoxification of heroin addicts. | Alternative therapies in health and medicine 20020101 |
| Alpha2-adrenergic agonists in opioid withdrawal. | Addiction (Abingdon, England) 20020101 |
| Acceptability and availability of pharmacological interventions for substance misuse by British NHS treatment services. | Addiction (Abingdon, England) 20020101 |
| Two methods of community detoxification from opiates: an open-label comparison of lofexidine and buprenorphine. | Drug and alcohol dependence 20011201 |
| Repeated lofexidine treatment attenuates stress-induced, but not drug cues-induced reinstatement of a heroin-cocaine mixture (speedball) seeking in rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010901 |
| Randomized placebo controlled trial of lofexidine hydrochloride for chronic pelvic pain in women. | Human reproduction (Oxford, England) 20010801 |
| Lofexidine versus clonidine in rapid opiate detoxification. | Journal of substance abuse treatment 20010701 |
| Alpha2 adrenergic agonists for the management of opioid withdrawal. | The Cochrane database of systematic reviews 20010101 |
| A double-blind randomized placebo-controlled trial of lofexidine in alcohol withdrawal: lofexidine is not a useful adjunct to chlordiazepoxide. | Alcohol and alcoholism (Oxford, Oxfordshire) 20010101 |
| [Therapy of tic disorders apparently of organic origin in a multi-morbid 5-year-old patient with lofexidine (Britlofex) and clonidine (Catapressan)]. | Wiener medizinische Wochenschrift (1946) 20010101 |
| Alpha-2 adrenergic receptor agonists block stress-induced reinstatement of cocaine seeking. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20000801 |
| Accelerated lofexidine treatment regimen compared with conventional lofexidine and methadone treatment for in-patient opiate detoxification. | Drug and alcohol dependence 19980501 |
| Double-blind randomised controlled trial of lofexidine versus clonidine in the treatment of heroin withdrawal. | Drug and alcohol dependence 19971125 |
| Alcohol withdrawal syndromes: clinical management with lofexidine. | Alcoholism, clinical and experimental research 19850101 |
| Animal experiments on the safety pharmacology of lofexidine. | Arzneimittel-Forschung 19820101 |