Home Halogens Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-

Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-

CAS No.:
305-03-3
Catalog Number:
AG0030DZ
Molecular Formula:
C14H19Cl2NO2
Molecular Weight:
304.2122
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
≥98%
1 week
United States
$91
- +
500mg
≥98%
1 week
United States
$110
- +
1g
≥98%
1 week
United States
$147
- +
Product Description
Catalog Number:
AG0030DZ
Chemical Name:
Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-
CAS Number:
305-03-3
Molecular Formula:
C14H19Cl2NO2
Molecular Weight:
304.2122
MDL Number:
MFCD00021783
IUPAC Name:
4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid
InChI:
InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
InChI Key:
JCKYGMPEJWAADB-UHFFFAOYSA-N
SMILES:
ClCCN(c1ccc(cc1)CCCC(=O)O)CCCl
EC Number:
206-162-0
UNII:
18D0SL7309
UN Number:
2811
Properties
Complexity:
250  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
303.079g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
304.211g/mol
Monoisotopic Mass:
303.079g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
40.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.7  
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Evaluation of the (R)VAD+C regimen for the treatment of newly diagnosed mantle cell lymphoma. Combined results of two prospective phase II trials from the French GOELAMS group. Haematologica 20100801
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Delivery of chlorambucil using an acoustically-triggered perfluoropentane emulsion. Ultrasound in medicine & biology 20100801
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DNA instability at chromosomal fragile sites in cancer. Current genomics 20100801
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Comparative study of genetic activity of chlorambucil's active metabolite steroidal esters: the role of steroidal skeleton on aneugenic potential. Mutation research 20100707
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Proposing an algorithm for treatment of different manifestations of neuro-Behcet's disease. Clinical rheumatology 20100601
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Infliximab for the treatment of refractory scleritis. The British journal of ophthalmology 20100501
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Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells. The pharmacogenomics journal 20100401
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Treatment course of steroid-dependent nephrotic syndrome: emphasized on treatment effect. Nephrology (Carlton, Vic.) 20100401
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The oncogene DEK promotes leukemic cell survival and is downregulated by both Nutlin-3 and chlorambucil in B-chronic lymphocytic leukemic cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20100315
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Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line. Cancer science 20100301
Design, synthesis and biological evaluation of estradiol-chlorambucil hybrids as anticancer agents. Bioorganic & medicinal chemistry letters 20100301
Novel melphalan and chlorambucil derivatives of 2,2,6,6-tetramethyl-1-piperidinyloxy radicals: synthesis, characterization, and biological evaluation in vitro. Chemical & pharmaceutical bulletin 20100301
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Pharmacokinetics and pharmacodynamics of chlorambucil delivered in long-circulating nanoemulsion. Journal of drug targeting 20100201
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An evaluation of the cost-effectiveness of rituximab in combination with chemotherapy for the first-line treatment of follicular non-Hodgkin's lymphoma in the UK. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101
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A biophysical elucidation for less toxicity of agglutinin than abrin-a from the seeds of Abrus precatorius in consequence of crystal structure. Journal of biomedical science 20100101
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A case to illustrate the role of ophthalmologist in systemic lupus erythematosus. Indian journal of dermatology 20100101
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Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL). Journal of blood medicine 20100101
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Time-course study of the immunotoxic effects of the anticancer drug chlorambucil in the rat. Toxicologic pathology 20091201
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Revised guidelines for management of steroid-sensitive nephrotic syndrome. Indian journal of nephrology 20080101
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Prospective controlled study on mycophenolate mofetil and prednisolone in the treatment of membranous nephropathy with nephrotic syndrome. Nephrology (Carlton, Vic.) 20071201
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Primary cutaneous marginal zone B-cell lymphoma in a patient with chronic lymphocytic leukaemia. The British journal of dermatology 20070901
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Advances in immunosuppressive therapy. Seminars in respiratory and critical care medicine 20070801
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New cyclodextrin bioconjugates for active tumour targeting. Journal of drug targeting 20070701
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A brief primer on treatments of cutaneous T cell lymphoma, newly approved or late in development. Journal of drugs in dermatology : JDD 20070701
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Low-dose methylprednisolone pulse therapy in Chinese children with steroid resistant focal segmental glomerulosclerosis. Pediatrics international : official journal of the Japan Pediatric Society 20070601
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Comparison of the clinical manifestations, brain MRI and prognosis between neuroBeçhet's disease and neuropsychiatric lupus. The Korean journal of internal medicine 20070601
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Inhalation and dermal exposure to eight antineoplastic drugs in an industrial laundry facility. International archives of occupational and environmental health 20070401
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Disseminated xanthogranulomas associated with adult T-cell leukaemia/lymphoma: a case report and review the association of haematologic malignancies. Journal of the European Academy of Dermatology and Venereology : JEADV 20070401
Suggested guidelines for patient monitoring: hepatic and hematologic toxicity attributable to systemic dermatologic drugs. Dermatologic clinics 20070401
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Two novel nucleoside ester derivatives of chlorambucil as potential antileukemic prodrugs: a preliminary study. Anti-cancer drugs 20070301
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Pulmonary hypertension and amyloidosis--an uncommon association: a case report and review of the literature. Journal of general internal medicine 20070301
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Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. PLoS medicine 20070301
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The treatment of polycythaemia vera: an update in the JAK2 era. Internal and emergency medicine 20070301
Fluocinolone acetonide intravitreal sustained release device--a new addition to the armamentarium of uveitic management. International journal of nanomedicine 20070301
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Use of rituximab in patients with follicular lymphoma. Clinical oncology (Royal College of Radiologists (Great Britain)) 20070201
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Chlorambucil - rituximab as first line combination therapy in follicular non-Hodgkin's lymphoma: a clinical and biological analysis. Leukemia & lymphoma 20070201
Molecular mechanism of nitrogen mustard induced leukocyte(s) chemotaxis. Medical hypotheses 20070101
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Therapeutic approach to FSGS in children. Pediatric nephrology (Berlin, Germany) 20070101
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Extensive exfoliative dermatitis induced by chlorambucil. American journal of hematology 20061101
Toward building a database of bifunctional probes for the MS3D investigation of nucleic acids structures. Journal of the American Society for Mass Spectrometry 20061101
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Case of chlorambucil-induced seizure. Internal medicine journal 20061001
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Oral chlorambucil for extranodal, marginal zone, B-cell lymphoma of mucosa-associated lymphoid tissue of the orbit. Ophthalmology 20060701
Molecular characterization of chronic lymphocytic leukemia with two distinct cell populations: Evidence for separate clonal origins. American journal of clinical pathology 20060701
A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate. Cell cycle (Georgetown, Tex.) 20060701
Successful therapeutic use of rituximab in refractory membranous glomerulonephritis. Clinical nephrology 20060701
Spontaneous remission of therapy-resistant minimal change nephritis in an adult woman 12 years after onset of the disease. Wiener medizinische Wochenschrift (1946) 20060701
Non-Hodgkin's lymphoma in patients 80 years of age or older. Annals of oncology : official journal of the European Society for Medical Oncology 20060601
The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro. Leukemia 20060601
Structure-anti-leukemic activity relationship study of B- and D-ring modified and non-modified steroidal esters of chlorambucil. Anti-cancer drugs 20060601
Detection of Chlamydia pneumoniae in a bilateral orbital mucosa-associated lymphoid tissue lymphoma. American journal of ophthalmology 20060601
Plasmapheresis for refractory urticarial vasculitis in a patient with B-cell chronic lymphocytic leukemia. Journal of drugs in dermatology : JDD 20060601
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The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo. The Journal of pharmacology and experimental therapeutics 20060501
A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Annals of hematology 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
New agents in chronic lymphocytic leukemia. Current treatment options in oncology 20060501
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The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative. The Journal of biological chemistry 20060414
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Adefovir added to lamivudine for hepatitis B recurrent infection in refractory B-cell chronic lymphocytic leukemia on prolonged therapy with Campath-1H. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20060401
Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060401
Chlorambucil therapy in children with steroid-resistant nephrotic syndrome. Saudi medical journal 20060401
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Chronic lymphocytic leukaemia, synchronous small cell carcinoma and squamous neoplasia of the urinary bladder in a paraplegic man following long-term phenoxybenzamine therapy. Spinal cord 20060301
Necrobiotic xanthogranuloma with paraproteinaemia. Clinical and experimental dermatology 20060301
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Prognostic impact of multidrug resistance gene expression on the management of breast cancer in the context of adjuvant therapy based on a series of 171 patients. British journal of cancer 20060227
[Long-term course of necrobiotic xanthogranuloma with ocular involvement]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20060201
A randomized pilot trial comparing methylprednisolone plus a cytotoxic agent versus synthetic adrenocorticotropic hormone in idiopathic membranous nephropathy. American journal of kidney diseases : the official journal of the National Kidney Foundation 20060201
Transformation and progression of Waldenström's macroglobulinemia following cladribine therapy in two cases: natural evolution or iatrogenic causation? American journal of hematology 20060201
Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data. Anti-cancer drugs 20060101
PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions. Bioconjugate chemistry 20060101
Identification and characterization of the carboxy-terminal region of Sip-1, a novel autoantigen in Behçet's disease. Arthritis research & therapy 20060101
Evolution of treatment of high-risk metastatic gestational trophoblastic tumors: Ain Shams University experience. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Gestational trophoblastic tumor in pregnancy: a case report and review of the literature. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Free radical theory of autoimmunity. Theoretical biology & medical modelling 20060101
Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data. Arthritis research & therapy 20060101
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Two reciprocal translocations provide new clues to the high mutability of the Grid2 locus. Mammalian genome : official journal of the International Mammalian Genome Society 20050101
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Behçet's disease, myelodysplastic syndrome, trisomy 8, gastroenterological involvement--an association. Clinical and experimental rheumatology 20050101
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Primary malignant lymphoma of the testis. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 20050101
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Aromatic oligopeptides with chlorambucil moiety--synthesis and biological evaluation. Acta poloniae pharmaceutica 20050101
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Establishment and characterisation of a human carcinoma cell line with acquired resistance to Aplidin. British journal of cancer 20041004
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In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity. Molecular cancer therapeutics 20040701
Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards. Chemical research in toxicology 20040701
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Advances in chemotherapy for chronic lymphocytic leukemia. Seminars in hematology 20040701
IgD kappa myeloma: a new case. Joint, bone, spine : revue du rhumatisme 20040701
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ChlVPP/ABVVP, a first line 'hybrid' combination chemotherapy for advanced Hodgkin's lymphoma: a retrospective analysis. British journal of haematology 20040601
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Necrobiotic xanthogranuloma with cutaneous and cerebral manifestations. Case report and review of the literature. Journal of neurosurgery 20040601
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Long-term maintenance therapy with weekly chlorambucil in patients with symptomatic or progressive follicular lymphoma. Leukemia & lymphoma 20040601
Amidine analogue of chlorambucil is a stronger inhibitor of protein and DNA synthesis in breast cancer MCF-7 cells than is the parent drug. European journal of pharmacology 20040525
Effects of tumour acidification with glucose+MIBG on the spontaneous metastatic potential of two murine cell lines. British journal of cancer 20040504
Recurrence of severe steroid dependency in cyclosporin A-treated childhood idiopathic nephrotic syndrome. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040501
Remarkable response to rituximab in a patient with atypical CD20(++) mantle cell lymphoma of the bone marrow leading to severe pancytopenia. Annals of hematology 20040501
Cutaneous B-cell lymphoma of nails, pinna and nose treated with chlorambucil. The Australasian journal of dermatology 20040501
Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium. Leukemia research 20040501
Use of corticosteroid sparing systemic immunosuppression for treatment of corticosteroid dependent optic neuritis not associated with demyelinating disease. The British journal of ophthalmology 20040501
Anti-CD20 monoclonal antibody (rituximab) treatment for hepatitis C-negative therapy-resistant essential mixed cryoglobulinemia with renal and cardiac failure. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040501
Bryostatin induces protein kinase C modulation, Mcl-1 up-regulation and phosphorylation of Bcl-2 resulting in cellular differentiation and resistance to drug-induced apoptosis in B-cell chronic lymphocytic leukemia cells. Leukemia & lymphoma 20040501
Myelodysplasia and acute myeloid leukaemia in a case of rheumatoid arthritis with secondary amyloidosis treated with chlorambucil. The Journal of the Association of Physicians of India 20040501
Comprehensive analysis of risk factors associating with Hepatitis B virus (HBV) reactivation in cancer patients undergoing cytotoxic chemotherapy. British journal of cancer 20040405
Pemphigus: current therapy. Veterinary dermatology 20040401
Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects. Molecular pharmacology 20040401
Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia. Postgraduate medical journal 20040401
Waldenström's macroglobulinemia: prognostic factors and recent therapeutic advances. Clinical and experimental medicine 20040401
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[Waldenstrom macroglobulinemia]. Praxis 20040331
Synthesis and biological evaluation of novel chloroethylaminoanthraquinones with potent cytotoxic activity against cisplatin-resistant tumor cells. Journal of medicinal chemistry 20040325
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2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT. British journal of cancer 20040308
Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs. Blood 20040301
Imatinib sensitizes CLL lymphocytes to chlorambucil. Leukemia 20040301
Tacrolimus therapy in pediatric patients with treatment-resistant nephrotic syndrome. Pediatric nephrology (Berlin, Germany) 20040301
Detection of mitotic recombination and sex chromosome loss induced by adriamycin, chlorambucil, demecolcine, paclitaxel and vinblastine in somatic cells of Drosophila melanogaster in vivo. Mutagenesis 20040301
Reactions of N,N-bis(2-chloroethyl)-p-aminophenylbutyric acid (chlorambucil) with 2'-deoxycytidine, 2'-deoxy-5-methylcytidine, and thymidine. Chemical research in toxicology 20040301
Increased cyclooxygenase-2 (COX-2): a potential role in the pathogenesis of lymphoma. Leukemia research 20040201
Pentostatin (Nipent) in the treatment of chronic lymphocyte leukemia and hairy cell leukemia. Expert review of anticancer therapy 20040201
Long-standing Bell's palsy and ipsilateral conjunctival maltoma. American journal of hematology 20040201
Limited field radiotherapy for early stage, infra-diaphragmatic Hodgkin's lymphoma. Clinical oncology (Royal College of Radiologists (Great Britain)) 20040201
Synthesis and biological evaluation of new cyclic amidine analogs of chlorambucil. Farmaco (Societa chimica italiana : 1989) 20040201
Urinary immunocytology for primary bladder B cell lymphoma. Urology 20040201
[Drug-resistant B cell chronic lymphocytic leukemia safely treated with rituximab to control leukemic cell increment and platelet transfusion dependence]. Gan to kagaku ryoho. Cancer & chemotherapy 20040201
[Chronic lymphocytic leukemia--the old and the new]. Therapeutische Umschau. Revue therapeutique 20040201
High dose chlorambucil in the treatment of lymphoid malignancies. Leukemia & lymphoma 20040201
Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity. The Journal of pharmacology and experimental therapeutics 20040101
Long-acting beta2-adrenergic formoterol and salmeterol induce the apoptosis of B-chronic lymphocytic leukaemia cells. British journal of haematology 20040101
Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia. American journal of hematology 20040101
Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040101
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[Membranous kidney diseases in adults]. Medicina 20040101
Pentostatin, chlorambucil and prednisone therapy for B-chronic lymphocytic leukemia: a phase I/II study by the Eastern Cooperative Oncology Group study E1488. Leukemia & lymphoma 20040101
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Chemotherapy combination treatment regimens with fludarabine in chronic lymphocytic leukemia. The hematology journal : the official journal of the European Haematology Association 20040101
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[Relapsing nephrotic syndrome in a diabetic patient with minimal change]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
Conjugation of a hairpin pyrrole-imidazole polyamide to a quinone methide for control of DNA cross-linking. Bioconjugate chemistry 20040101
Extended venous thrombosis in Adamantiades-Behçet's disease. European journal of dermatology : EJD 20040101
UVA/UVA1 phototherapy and PUVA photochemotherapy in connective tissue diseases and related disorders: a research based review. BMC dermatology 20040101
Etanercept treatment of renal amyloidosis complicating rheumatoid arthritis. Internal medicine journal 20040101
Behçet's disease in Moroccan children: a report of 12 cases. Scandinavian journal of rheumatology 20040101
The in vitro effect of gefitinib ('Iressa') alone and in combination with cytotoxic chemotherapy on human solid tumours. BMC cancer 20040101
[Treatment of idiopathic membranous nephropathy]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20040101
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Chlorambucil. Report on carcinogens : carcinogen profiles 20040101
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High dose methylprednisolone can induce remissions in CLL patients with p53 abnormalities. Annals of hematology 20031201
Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP). Annals of oncology : official journal of the European Society for Medical Oncology 20031201
[Standard and experimental therapy of cutaneous T-cell lymphoma]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20031201
Primary ovarian cancer chemotherapy: current standards of care. British journal of cancer 20031201
Feline pemphigus foliaceus: a retrospective analysis of 57 cases. Veterinary dermatology 20031201
Mood alterations in patients treated with chlorambucil. Clinical lymphoma 20031201
[Membranous nephropathy]. La Revue du praticien 20031130
Synthesis and pharmacokinetic profile of a quaternary ammonium derivative of chlorambucil, a potential anticancer drug for the chemotherapy of chondrosarcoma. Bioorganic & medicinal chemistry 20031117
Infertility rates following POMB/ACE chemotherapy for male and female germ cell tumours - a retrospective long-term follow-up study. British journal of cancer 20031117
Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress. Toxicology 20031115
Role of the TRAIL/APO2-L death receptors in chlorambucil- and fludarabine-induced apoptosis in chronic lymphocytic leukemia. Oncogene 20031113
Multicentric Castleman's disease treated with antivirals and immunosuppressants. Journal of medical virology 20031101
Multidrug resistance protein-6 (MRP6) in human dermal fibroblasts. Comparison between cells from normal subjects and from Pseudoxanthoma elasticum patients. Matrix biology : journal of the International Society for Matrix Biology 20031101
[Asynchronous occurrence of three neoplastic diseases: chronic B-cell lymphatic leukemia, renal carcinoma and prostatic adenocarcinoma]. Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti 20031101
Identification and prediction of promiscuous aggregating inhibitors among known drugs. Journal of medicinal chemistry 20031009
Chlorambucil in combination with induction and maintenance rituximab is feasible and active in indolent non-Hodgkin's lymphoma. British journal of haematology 20031001
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Synthesis of poly(ethylene glycol) with sulfadiazine and chlorambucil end groups and investigation of its antitumor activity. Bioorganic & medicinal chemistry letters 20030804
Increased resistance to nitrogen mustards and antifolates following in vitro selection of murine fibroblasts and primary hematopoietic cells transduced with a bicistronic retroviral vector expressing the rat glutathione S-transferase A3 and a mutant dihydrofolate reductase. Cancer gene therapy 20030801
Management of nephrotic syndrome in children. Pharmacotherapy 20030801
Mantle cell lymphoma. Current treatment options in oncology 20030801
Chronic lymphocytic leukemia and multiple myeloma in the same patient: case report. Leukemia & lymphoma 20030801
Treatment of nephrotic syndrome in children and controlled trials. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030801
Structure-activity studies of novel amidine analogues of chlorambucil: correlation of cytotoxic activity with DNA-binding affinity and topoisomerase II inhibition. Archiv der Pharmazie 20030801
Validation of a flow cytometric acridine orange micronuclei methodology in rats. Mutation research 20030725
[Current concepts in chronic lymphocytic leukemia. Better chances for young patients]. MMW Fortschritte der Medizin 20030710
HOVON 47/EORTC 20013: chlorambucil vs 2x2 Gy involved field radiotherapy in stage III/IV previously untreated follicular lymphoma patients. Annals of hematology 20030701
Therapy-resistant focal and segmental glomerulosclerosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030701
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Treatment of de novo and recurrent membranous nephropathy in renal transplant patients. Seminars in nephrology 20030701
Vitamin E analogues as inducers of apoptosis: structure-function relation. British journal of cancer 20030616
Expression of apoptosis regulators in cutaneous T-cell lymphoma (CTCL) cells. The Journal of pathology 20030601
The effect of chlorambucil treatment on cytogenetic parameters in chronic lymphocytic leukemia patients. Cancer genetics and cytogenetics 20030601
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Autoimmune thrombocytopenia due to chronic lymphocytic leukemia treated with fludarabine. The Annals of pharmacotherapy 20030501
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Conjugation of chlorambucil with GSH by GST purified from human colon adenocarcinoma cells and its inhibition by plant polyphenols. Life sciences 20030425
Enabling ScFvs as multi-drug carriers: a dendritic approach. Bioorganic & medicinal chemistry 20030417
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Treatment of indolent B-Cell nonfollicular lymphomas: final results of the LL01 randomized trial of the Gruppo Italiano per lo Studio dei Linfomi. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030415
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Low-dose continuous chemotherapy for metastatic melanoma: a phase II trial. Melanoma research 20030401
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Waldenstrom's macroglobulinemia: a retrospective analysis of 40 patients from 1972 to 2001. Seminars in oncology 20030401
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Transverse myelitis occurring in association with primary biliary cirrhosis and Sjogren's syndrome. Digestive diseases and sciences 20030401
Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study. Blood 20030301
Primary malignant follicular lymphoma of the cervix: a rare cause of postmenopausal bleeding. BJOG : an international journal of obstetrics and gynaecology 20030301
Reactions of N,N-bis(2-chloroethyl)-p-aminophenylbutyric acid (chlorambucil) with 2'-deoxyadenosine. Chemical research in toxicology 20030301
Chlornaphazine and chlorambucil induce dominant lethal mutations in male mice. Mutation research 20030301
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Toxicity of the alkylating agent bendamustin. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement 19850101
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Enhancement by electron-affinic agents of the therapeutic effects of cytotoxic agents against the KHT tumor: structure-activity relationships. International journal of radiation oncology, biology, physics 19820101
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Chlorambucil neurotoxicity: report of two cases. Helvetica paediatrica acta 19800701
Spindle cell cancer of bladder during cyclophosphamide therapy for Wegener's granulomatosis. The American journal of surgical pathology 19800401
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Focal fits during chlorambucil therapy. Postgraduate medical journal 19791101
Skin sensitizing properties of arylalcanoic acids and their analogues. Contact dermatitis 19790901
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Chronic lymphatic leukaemia, chlorambucil, and sensorimotor peripheral neuropathy. British medical journal 19771112
[Longitudinal study in children with the nephrotic syndrome and minimal glomerular lesion]. Boletin medico del Hospital Infantil de Mexico 19770101
Therapeutic studies in NZB/NZW F1 mice. V. Comparison of cyclophosphamide and chlorambucil. Arthritis and rheumatism 19770101
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Carcinoma of the urinary bladder in patients receiving cyclophosphamide. The New England journal of medicine 19750807
Metabolic complications of aggressive therapy of chronic lymphocytic leukemia. The American journal of the medical sciences 19740501
Long-lasting remission of Behcet's disease after chlorambucil therapy. The British journal of ophthalmology 19730901
Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. British medical journal 19730428
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