Home Other Building Blocks Ng,Ng-dimethylarginine hydrochloride

Ng,Ng-dimethylarginine hydrochloride

CAS No.:
30315-93-6
Catalog Number:
AG002ZOL
Molecular Formula:
C8H18N4O2
Molecular Weight:
202.2541
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
95%
In Stock USA
United States
$248
- +
1g
95%
In Stock USA
United States
$619
- +
5g
95%
In Stock USA
United States
$1875
- +
Product Description
Catalog Number:
AG002ZOL
Chemical Name:
Ng,Ng-dimethylarginine hydrochloride
CAS Number:
30315-93-6
Molecular Formula:
C8H18N4O2
Molecular Weight:
202.2541
MDL Number:
MFCD00038406
IUPAC Name:
(2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid
InChI:
InChI=1S/C8H18N4O2/c1-12(2)8(10)11-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14)/t6-/m0/s1
InChI Key:
YDGMGEXADBMOMJ-LURJTMIESA-N
SMILES:
N[C@H](C(=O)O)CCCNC=NN(C)C
Properties
Complexity:
215  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
202.143g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
202.258g/mol
Monoisotopic Mass:
202.143g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
105A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.6  
Literature
Title Journal
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Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension? Pulmonary medicine 20160101
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INF-β1b therapy modulates L-arginine and nitric oxide metabolism in patients with relapse remittent multiple sclerosis. Journal of the neurological sciences 20121215
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Reduced plasma levels of asymmetric di-methylarginine (ADMA) in patients with alcohol dependence normalize during withdrawal. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20121101
Paraoxonase lactonase activity (PON-HTLase), asymmetric dimethylarginine (ADMA) and platelet activating factor-acetylhydrolase (PAF-AH) activity in non-obese women with PCOS. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20121101
Do cardiac risk factors affect the homocysteine and asymmetric dimethylarginine relationship in patients with coronary artery diseases? Clinical biochemistry 20121101
Clinical remission following treatment with tumour necrosis factor-alpha antagonists is not accompanied by changes in asymmetric dimethylarginine in patients with rheumatoid arthritis. Clinical biochemistry 20121101
Feasibility of landiolol and bisoprolol for prevention of atrial fibrillation after coronary artery bypass grafting: a pilot study. The Journal of thoracic and cardiovascular surgery 20121101
Serum asymmetric dimethylarginine, apelin, and tumor necrosis factor-α levels in non-obese women with polycystic ovary syndrome. Steroids 20121101
Weight loss and vascular inflammatory markers in overweight women with and without polycystic ovary syndrome. Reproductive biomedicine online 20121101
The L-arginine/asymmetric dimethylarginine ratio is improved by anti-tumor necrosis factor-α therapy in inflammatory arthropathies. Associations with aortic stiffness. Atherosclerosis 20121101
Actin cytoskeleton-dependent pathways for ADMA-induced NF-κB activation and TGF-β high expression in human renal glomerular endothelial cells. Acta biochimica et biophysica Sinica 20121101
Anti-hypertensive effects of shichimotsukokato in 5/6 nephrectomized Wistar rats mediated by the DDAH-ADMA-NO pathway. Journal of natural medicines 20121001
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Proteinuria elevates asymmetric dimethylarginine levels via protein arginine methyltransferase-1 overexpression in a rat model of nephrotic syndrome. Life sciences 20120924
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Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells. Amino acids 20120901
Addition of liraglutide in patients with Type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function. Diabetic medicine : a journal of the British Diabetic Association 20120901
Endothelial nitric oxide synthase enhancer for protection of endothelial function from asymmetric dimethylarginine-induced injury in human internal thoracic artery. The Journal of thoracic and cardiovascular surgery 20120901
Vascular effects of nebivolol added to hydrochlorothiazide in African Americans with hypertension and echocardiographic evidence of diastolic dysfunction: the NASAA study. Journal of cardiovascular pharmacology and therapeutics 20120901
The effect of valsartan and nebivolol treatment on ADMA and pentraxin-3 levels in hypertensive patients. Medical hypotheses 20120901
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The CSF concentration of ADMA, but not of ET-1, is correlated with the occurrence and severity of cerebral vasospasm after subarachnoid hemorrhage. Neuroscience letters 20120822
Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction. Clinical journal of the American Society of Nephrology : CJASN 20120807
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Increased asymmetric dimethylarginine (ADMA) dimethylaminohydrolase (DDAH) activity in childhood hypercholesterolemia type II. Amino acids 20120801
Birth by cesarean section is associated with elevated neonatal plasma levels of dimethylarginines. Pediatrics international : official journal of the Japan Pediatric Society 20120801
Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level. Metabolism: clinical and experimental 20120801
High tea and vegetable consumption is associated with low ADMA generation in older healthy subjects. Metabolism: clinical and experimental 20120801
Nitric oxide and L-arginine metabolism in a devascularized porcine model of acute liver failure. American journal of physiology. Gastrointestinal and liver physiology 20120801
Aqueous humour and serum concentration of asymmetric dimethyl arginine in pseudoexfoliation syndrome. The British journal of ophthalmology 20120801
Regulation of endothelial nitric oxide synthase and asymmetric dimethylarginine by matrine attenuates isoproterenol-induced acute myocardial injury in rats. The Journal of pharmacy and pharmacology 20120801
The role of homocysteine, asymmetric dimethylarginine and nitric oxide in pre-eclampsia. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20120801
Diagnostical significance of dimethylarginine in the development of hepatorenal syndrome in patients with alcoholic liver cirrhosis. Vojnosanitetski pregled 20120801
Asymmetric dimethylarginine and vascular indices of atherosclerosis in patients after coarctation of aorta repair. International journal of cardiology 20120726
Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis. Journal of the neurological sciences 20120715
Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I. Free radical biology & medicine 20120715
The impact of pioglitazone on ADMA and oxidative stress markers in patients with type 2 diabetes. Primary care diabetes 20120701
Evaluation of asymmetric dimethylarginine, arginine, and carnitine metabolism in pediatric sepsis. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20120701
Flow-evoked vasodilation is blunted in penile arteries from Zucker diabetic fatty rats. The journal of sexual medicine 20120701
The effect of diet and exercise on markers of endothelial function in overweight and obese women with polycystic ovary syndrome. Human reproduction (Oxford, England) 20120701
Reduced renal plasma clearance does not explain increased plasma asymmetric dimethylarginine in hypertensive subjects with mild to moderate renal insufficiency. American journal of physiology. Renal physiology 20120701
The association between serum asymmetric dimethyl arginine levels and a history of gestational diabetes among healthy women. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20120701
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Human hemoglobin does not contain asymmetric dimethylarginine (ADMA). Nitric oxide : biology and chemistry 20120630
Impairment of the extrusion transporter for asymmetric dimethyl-L-arginine: a novel mechanism underlying vasospastic angina. Biochemical and biophysical research communications 20120629
HIV replication, inflammation, and the effect of starting antiretroviral therapy on plasma asymmetric dimethylarginine, a novel marker of endothelial dysfunction. Journal of acquired immune deficiency syndromes (1999) 20120601
Plasma asymmetric dimethylarginine and mortality in patients with acute decompensation of chronic heart failure. Heart (British Cardiac Society) 20120601
Nitric oxide synthase, ADMA, SDMA, and nitric oxide activity in the paraventricular nucleus throughout the etiology of renal wrap hypertension. American journal of physiology. Heart and circulatory physiology 20120601
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Asymmetric dimethylarginine in adults with cystathionine β-synthase deficiency. Atherosclerosis 20120601
Dimethylarginine dimethylaminohydrolase 1 regulates nerve growth factor-promoted differentiation of PC12 cells in a nitric oxide-dependent but asymmetric dimethylargenine-independent manner. Journal of neuroscience research 20120601
Plasma asymmetric dimethylarginine in patients with acute decompensation of chronic heart failure. Heart (British Cardiac Society) 20120601
Urinary asymmetric dimethylarginine (ADMA) is a predictor of mortality risk in patients with coronary artery disease. International journal of cardiology 20120503
Cellular hypomethylation is associated with impaired nitric oxide production by cultured human endothelial cells. Amino acids 20120501
Imbalance of arginine and asymmetric dimethylarginine is associated with markers of circulatory failure, organ failure and mortality in shock patients. The British journal of nutrition 20120501
In vivo nitric oxide synthesis, insulin sensitivity, and asymmetric dimethylarginine in obese subjects without and with metabolic syndrome. Metabolism: clinical and experimental 20120501
Effect of nisoldipine and olmesartan on endothelium-dependent vasodilation in essential hypertensive patients. CNS neuroscience & therapeutics 20120501
The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes. Gene 20120425
Elevation of serum asymmetrical and symmetrical dimethylarginine in patients with advanced glaucoma. Investigative ophthalmology & visual science 20120418
Role of the human erythrocyte in generation and storage of asymmetric dimethylarginine. American journal of physiology. Heart and circulatory physiology 20120415
Day-night variations in endothelial dysfunction markers and haemostatic factors in sleep apnoea. The European respiratory journal 20120401
Role of dimethylarginine dimethylaminohydrolase activity in regulation of tissue and plasma concentrations of asymmetric dimethylarginine in an animal model of prolonged critical illness. Metabolism: clinical and experimental 20120401
Elevated asymmetric dimethylarginine in plasma: an early marker for endothelial dysfunction in non-alcoholic fatty liver disease? Diabetes research and clinical practice 20120401
Endotoxemia exacerbates kidney injury and increases asymmetric dimethylarginine in young bile duct-ligated rats. Shock (Augusta, Ga.) 20120401
Inhibition of eNOS phosphorylation mediates endothelial dysfunction in renal failure: new effect of asymmetric dimethylarginine. Kidney international 20120401
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The impact of rapid atrial pacing on ADMA and endothelial NOS. International journal of cardiology 20120126
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L-arginine and asymmetric dimethylarginine are early predictors for survival in septic patients with acute liver failure. Mediators of inflammation 20120101
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Biomarkers in hemodialysis patients. Advances in clinical chemistry 20120101
Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression. PloS one 20120101
Serum levels of asymmetric dimethylarginine and apelin as potential markers of vascular endothelial dysfunction in early rheumatoid arthritis. Mediators of inflammation 20120101
Compensatory feto-placental upregulation of the nitric oxide system during fetal growth restriction. PloS one 20120101
Asymmetric dimethylarginine, endothelial dysfunction and renal disease. International journal of molecular sciences 20120101
Dimethylarginine dimethylaminohydrolase1 is an organ-specific mediator of end organ damage in a murine model of hypertension. PloS one 20120101
Plasma asymmetric dimethylarginine (ADMA) concentrations in patients with first and multiple episode schizophrenia. Psychiatry research 20111230
Stimulus-specific blockade of nitric oxide-mediated dilatation by asymmetric dimethylarginine (ADMA) and monomethylarginine (L-NMMA) in rat aorta and carotid artery. European journal of pharmacology 20111230
Detection and quantification of α-keto-δ-(N(G),N(G)-dimethylguanidino)valeric acid: a metabolite of asymmetric dimethylarginine. Analytical biochemistry 20111215
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase. Circulation 20111213
Plasma asymmetric dimethylarginine predicts death and major adverse cardiovascular events in individuals referred for coronary angiography. International journal of cardiology 20111201
Increased asymmetric dimethylarginine and enhanced inflammation are associated with impaired vascular reactivity in women with endometriosis. Atherosclerosis 20111201
Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium-derived hyperpolarizing factor in small arteries from rat. The Journal of pharmacology and experimental therapeutics 20111201
Ascorbic acid or L-arginine improves cutaneous microvascular function in chronic kidney disease. Journal of applied physiology (Bethesda, Md. : 1985) 20111201
Asymmetric dimethylarginine (ADMA): is really a biomarker for cardiovascular prognosis? International journal of cardiology 20111201
Levels of soluble advanced glycation end product-receptors and other soluble serum markers as indicators of diabetic neuropathy in the foot. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20111201
A dietary approach to increase in-stent stenosis and face validity of a rat model for arterial angioplasty and stenting. Atherosclerosis 20111201
Apelin-13 passes through the ADMA-damaged endothelial barrier and acts on vascular smooth muscle cells. Peptides 20111201
Relationships of osteoprotegerin with albuminuria and asymmetric dimethylarginine in essential hypertension: integrating vascular dysfunction. Expert opinion on therapeutic targets 20111201
Aliskiren prevents hypertension and reduces asymmetric dimethylarginine in young spontaneously hypertensive rats. European journal of pharmacology 20111130
Exercise blood pressure response is related to asymmetric dimethylarginine and osteoprotegerin in hypertension. International journal of cardiology 20111117
Cardiovascular involvement in psoriatic arthritis. Reumatismo 20111109
Synergistic adverse prognostic effects of asymmetric dimethylarginine and endothelial progenitor-related cells deficiency after elective coronary angioplasty. International journal of cardiology 20111103
Active site mutant dimethylarginine dimethylaminohydrolase 1 expression confers an intermediate tumour phenotype in C6 gliomas. The Journal of pathology 20111101
Asymmetric dimethylarginine concentration and recurrence of atrial tachyarrythmias after catheter ablation in patients with persistent atrial fibrillation. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20111101
The biochemistry of asthma. Biochimica et biophysica acta 20111101
The biological effect of pharmacological treatment on dimethylaminohydrolases (DDAH-1) and cationic amino acid transporter-1 (CAT-1) expression in patients with acute congestive heart failure. Microvascular research 20111101
Elevated plasma asymmetric dimethylarginine level in acute myocardial infarction patients as a predictor of poor prognosis and angiographic impaired reperfusion. Atherosclerosis 20111101
Endogenous hydrogen sulfide is involved in asymmetric dimethylarginine-induced protection against neurotoxicity of 1-methyl-4-phenyl-pyridinium ion. Neurochemical research 20111101
Unilateral nephrectomy causes an abrupt increase in inflammatory mediators and a simultaneous decrease in plasma ADMA: a study in living kidney donors. American journal of physiology. Renal physiology 20111101
Pseudomonas aeruginosa is associated with increased lung cytokines and asymmetric dimethylarginine compared with methicillin-resistant Staphylococcus aureus. Shock (Augusta, Ga.) 20111101
Sympathetic nerve traffic and asymmetric dimethylarginine in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN 20111101
Effect of smoking cessation on the number and adhesive properties of early outgrowth endothelial progenitor cells. International journal of cardiology 20111006
Effect of moderate and high-dose simvastatin on asymmetric dimethylarginine-homocysteine metabolic pathways in patients with newly detected severe hypercholesterolemia. Cardiovascular therapeutics 20111001
Asymmetric dimethylarginine level in hyperglycemic gestation. Endocrine 20111001
Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20111001
Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN 20111001
Changes in the arginine methylation of organ proteins during the development of diabetes mellitus. Diabetes research and clinical practice 20111001
Favorable effect of short-term lifestyle intervention on human paraoxonase-1 activity and adipokine levels in childhood obesity. Journal of the American College of Nutrition 20111001
Determination of asymmetric dimethyl arginine in human serum by liquid chromatography-tandem mass spectrometry: clinical application in hypertensive subjects. Clinical chemistry and laboratory medicine 20110906
Asymmetric dimethylarginine confers the communication between endothelial and smooth muscle cells and leads to VSMC migration through p38 and ERK1/2 signaling cascade. FEBS letters 20110902
Evaluation of asymmetric dimethylarginine, nitric oxide levels and associated independent variables in obese and lean patients with polycystic ovarian syndrome. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110901
Inflammatory-metabolic parameters in obese and nonobese normoandrogenemic polycystic ovary syndrome during metformin and oral contraceptive treatment. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110901
Asymmetric dimethylarginine levels in essential thrombocythemia--a retrospective analysis. Annals of hematology 20110901
Transient endothelial dysfunction following flow-mediated dilation assessment. Heart and vessels 20110901
Novel endothelial biomarkers: implications for periodontal disease and CVD. Journal of dental research 20110901
Relationship between plasma coenzyme Q10, asymmetric dimethylarginine and arterial stiffness in patients with phenotypic or genotypic familial hypercholesterolemia on long-term statin therapy. Atherosclerosis 20110901
Vascular endothelial function assessed by a noninvasive ultrasound method and serum asymmetric dimethylarginine concentrations in mild-to-moderate plaque-type psoriatic patients. Clinical biochemistry 20110901
Serum levels of arginase I are associated with left ventricular function after myocardial infarction. Clinical biochemistry 20110901
Chronic renal failure alters endothelial function in cerebral circulation in mice. American journal of physiology. Heart and circulatory physiology 20110901
Salt sensitivity in blacks: evidence that the initial pressor effect of NaCl involves inhibition of vasodilatation by asymmetrical dimethylarginine. Hypertension (Dallas, Tex. : 1979) 20110901
The effect of calcineurin inhibitors on endothelial and platelet function in renal transplant patients. Clinical nephrology 20110901
Late effects of renal transplantation on endothelial functions and cardiac morphology. Transplantation proceedings 20110901
Effects of walking on heart rate recovery, endothelium modulators and quality of life in patients with heart failure. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20110801
The levels of nitric oxide and asymmetric dimethylarginine in the rat endometriosis model. The journal of obstetrics and gynaecology research 20110801
Methionine-induced homocysteinemia impairs endothelial function in hypertensives: the role of asymmetrical dimethylarginine and antioxidant vitamins. American journal of hypertension 20110801
Asymmetric dimethylarginine and coronary artery calcium scores are increased in patients infected with human immunodeficiency virus. Atherosclerosis 20110801
Vascular function in the diagnostic categories of polycystic ovary syndrome. Human reproduction (Oxford, England) 20110801
Coronary flow reserve and asymmetric dimethylarginine levels: new measurements for identifying subclinical atherosclerosis in patients with psoriatic arthritis. The Journal of rheumatology 20110801
Effects of 7 days of arginine-alpha-ketoglutarate supplementation on blood flow, plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise. International journal of sport nutrition and exercise metabolism 20110801
Homocysteine and asymmetric dimethylarginine in relation to B vitamins in elderly people. Wiener klinische Wochenschrift 20110801
Role of asymmetric dimethylarginine in acute lung injury induced by cerebral ischemia/reperfusion injury in rats. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110801
C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow. American journal of respiratory cell and molecular biology 20110701
Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine. European journal of pediatrics 20110701
Serum asymmetric dimethylarginine (ADMA), homocysteine, vitamin B(12), folate levels, and lipid profiles in epileptic children treated with valproic acid. European journal of pediatrics 20110701
Asymmetric dimethylarginine in normotensive pregnant women with isolated fetal intrauterine growth restriction: a comparison with preeclamptic women with and without intrauterine growth restriction. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20110701
Asymmetric dimethylarginine impairs fibrinolytic activity in human umbilical vein endothelial cells via p38 MAPK and NF-κB pathways. Thrombosis research 20110701
Exercise training increases endothelial progenitor cells and decreases asymmetric dimethylarginine in peripheral arterial disease: a randomized controlled trial. Atherosclerosis 20110701
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine. Arteriosclerosis, thrombosis, and vascular biology 20110701
Serum retinol-binding protein 4, leptin, and plasma asymmetric dimethylarginine levels in obese and nonobese young women with polycystic ovary syndrome. Fertility and sterility 20110701
Asymmetric dimethylarginine and clinical outcomes in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN 20110701
Inflammation and asymmetric dimethylarginine for predicting death and cardiovascular events in ESRD patients. Clinical journal of the American Society of Nephrology : CJASN 20110701
DDAH says NO to ADMA. Arteriosclerosis, thrombosis, and vascular biology 20110701
Endothelial arginase II and atherosclerosis. Korean journal of anesthesiology 20110701
Robotic treadmill training improves cardiovascular function in spinal cord injury patients. International journal of cardiology 20110616
The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis. Science translational medicine 20110615
Plasma levels of asymmetric dimethylarginine in patients with biopsy-proven nonalcoholic fatty liver disease. Metabolism: clinical and experimental 20110601
Plasma dimethylarginines during the acute inflammatory response. European journal of clinical investigation 20110601
Asymmetric dimethylarginine in young people with Type 1 diabetes: a paradoxical association with HbA(1c). Diabetic medicine : a journal of the British Diabetic Association 20110601
Simultaneous gas chromatography-tandem mass spectrometry quantification of symmetric and asymmetric dimethylarginine in human urine. Analytical biochemistry 20110601
NO problem: arterial and venous endothelial function and erectile dysfunction. European urology 20110601
Relationship of asymmetric dimethylarginine with penile Doppler ultrasound parameters in men with vasculogenic erectile dysfunction. European urology 20110601
Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine. Coronary artery disease 20110601
Relationships between serum levels of thyroid hormones and serum concentrations of asymmetric dimethylarginine (ADMA) and N-terminal-pro-B-type natriuretic peptide (NT-proBNP) in patients with Graves' disease. Endocrine 20110601
Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity. Atherosclerosis 20110601
Arginine/asymmetric dimethylarginine ratio and cardiovascular risk factors in patients with predialytic chronic kidney disease. Clinical biochemistry 20110601
Oxidative stress and endothelial dysfunction in hypertension. Hypertension research : official journal of the Japanese Society of Hypertension 20110601
Chronic kidney disease: the silent enemy? Anesthesia and analgesia 20110601
The effect of pharmacological treatment on ADMA in patients with heart failure. Frontiers in bioscience (Elite edition) 20110601
Nitric oxide (NO) and asymmetric dimethylarginine (ADMA): their pathophysiological role and involvement in intracerebral hemorrhage. Neurological research 20110601
Elevated concentration of asymmetric dimethylarginine (ADMA) in individuals with metabolic syndrome. Nitric oxide : biology and chemistry 20110531
Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with cystic fibrosis. American journal of respiratory and critical care medicine 20110515
Asymmetric dimethylarginine: a novel biomarker of gastric mucosal injury? World journal of gastroenterology 20110507
Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes. European heart journal 20110501
Carotid restenosis is associated with plasma ADMA concentrations in carotid endarterectomy patients. Clinical chemistry and laboratory medicine 20110501
Serum asymmetric dimethylarginine levels in diabetic patients with neuropathy. Diabetes research and clinical practice 20110501
High concentrations of asymmetric dimethylarginine are associated with ST-segment resolution failure after reperfusion for acute myocardial infarction. Clinical chemistry and laboratory medicine 20110501
Weight loss improves endothelial function independently of ADMA reduction in severe obesity. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20110501
Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity. Atherosclerosis 20110501
Asymmetric dimethylarginine levels in Buerger's disease. Annals of vascular surgery 20110501
The role of asymmetric and symmetric dimethylarginines in renal disease. Nature reviews. Nephrology 20110501
[Alterations in reactive oxygen species and dimethylarginine dimethylaminohydrolase-asymmetric dimethyl-arginine system in the process of endothelial cell senescence induced by high glucose]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20110501
In patients with aortic stenosis increased flow-mediated dilation is independently associated with higher peak jet velocity and lower asymmetric dimethylarginine levels. American heart journal 20110501
Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. American journal of respiratory cell and molecular biology 20110401
Immunoregulatory effects of the flavonol quercetin in vitro and in vivo. European journal of nutrition 20110401
Low levels of asymmetric dimethylarginine in children with diabetes mellitus type I compared with healthy children. The Journal of pediatrics 20110401
Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients with type 2 diabetes mellitus. Clinical endocrinology 20110401
Association between asymmetric dimethylarginine and indices of vascular function in patients with essential hypertension. Blood pressure 20110401
Dimethylarginine dimethylaminohydrolase 1 modulates endothelial cell growth through nitric oxide and Akt. Arteriosclerosis, thrombosis, and vascular biology 20110401
Elevated concentrations of Nɛ-homocysteinyl-lysine isopeptide in acute myocardial infarction: links with ADMA formation. Clinical chemistry and laboratory medicine 20110401
Asymmetric dimethylarginine (ADMA) levels are increased in patients with fibromyalgia: correlation with tumor necrosis factor-α (TNF-α) and 8-iso-prostaglandin F(2α) (8-iso-PGF(2α)). Clinical biochemistry 20110401
Regional differences in hypertensive cardiovascular remodeling between fishing and farming communities in Japan. American journal of hypertension 20110401
Increased asymmetric dimethylarginine and nitric oxide levels in patients with migraine. The journal of headache and pain 20110401
The therapeutic potential of targeting endogenous inhibitors of nitric oxide synthesis. Nature reviews. Drug discovery 20110401
Protective effect of neferine on endothelial cell nitric oxide production induced by lysophosphatidylcholine: the role of the DDAH-ADMA pathway. Canadian journal of physiology and pharmacology 20110401
Left ventricular hypertrophy is associated with inflammation in sodium loaded subtotal nephrectomized rats. Biomedical research (Tokyo, Japan) 20110401
[Analysis of transporter function and development to clinical application]. Seikagaku. The Journal of Japanese Biochemical Society 20110401
AADMA as a marker of endothelial dysfunction in prediabetic women. Acta medica Indonesiana 20110401
cAMP phosphodiesterase inhibitors increases nitric oxide production by modulating dimethylarginine dimethylaminohydrolases. Circulation 20110322
Targeting dimethylarginine dimethylaminohydrolases in pulmonary arterial hypertension: a new approach to improve vascular dysfunction? Circulation 20110322
Increased production of asymmetric dimethylarginine (ADMA) in ankylosing spondylitis: association with other clinical and laboratory parameters. Joint, bone, spine : revue du rhumatisme 20110301
Emerging interface between metabolic syndrome and asthma. American journal of respiratory cell and molecular biology 20110301
Acute lung injury-induced collagen deposition is associated with elevated asymmetric dimethylarginine and arginase activity. Shock (Augusta, Ga.) 20110301
Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease. Journal of internal medicine 20110301
Serum paraoxonase 1 activity, asymmetric dimethylarginine levels, and brachial artery flow-mediated dilatation in women with polycystic ovary syndrome. Fertility and sterility 20110301
Inflammation and reduced endothelial function in the course of severe acute heart failure. Translational research : the journal of laboratory and clinical medicine 20110301
Increased plasma level of asymmetric dimethylarginine in hypertensive rats facilitates platelet aggregation: role of plasma tissue factor. Canadian journal of physiology and pharmacology 20110301
Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers. International journal of cancer 20110201
Association between plasma asymmetrical dimethylarginine activity and severity of aortic valve stenosis. Journal of cardiovascular medicine (Hagerstown, Md.) 20110201
N-3 polyunsaturated fatty acids early supplementation improves ultrasound indices of endothelial function, but not through NO inhibitors in patients with acute myocardial infarction: N-3 PUFA supplementation in acute myocardial infarction. Clinical nutrition (Edinburgh, Scotland) 20110201
Ramipril retards development of aortic valve stenosis in a rabbit model: mechanistic considerations. British journal of pharmacology 20110201
Posttranslational arginine methylation of lamin A/C during myoblast fusion. Biochimica et biophysica acta 20110201
Asymmetric dimethylarginine in ELBW newborns exposed to chorioamnionitis. Early human development 20110201
Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: a model related to metabolic syndrome. Atherosclerosis 20110201
The L-arginine-asymmetric dimethylarginine ratio is strongly related to the severity of chronic heart failure. No effects of exercise training. Journal of cardiac failure 20110201
Asymmetric dimethylarginine: clinical applications in pediatric medicine. Journal of the Formosan Medical Association = Taiwan yi zhi 20110201
Asymmetric dimethylarginine as a risk marker for early-onset ischemic stroke in Indian population. Clinica chimica acta; international journal of clinical chemistry 20110114
Characterization of C-alkyl amidines as bioavailable covalent reversible inhibitors of human DDAH-1. ChemMedChem 20110103
Effect of a single hemodialysis session on endothelial dysfunction. Journal of nephrology 20110101
Asymmetric dimethylarginine (ADMA) induces chronic kidney disease through a mechanism involving collagen and TGF-β1 synthesis. The Journal of pathology 20110101
Transplantation of endothelial progenitor cells overexpressing endothelial nitric oxide synthase enhances inhibition of neointimal hyperplasia and restores endothelium-dependent vasodilatation. Microvascular research 20110101
Plasma asymmetric dimethylarginine (ADMA) levels and atherosclerotic disease in ankylosing spondylitis: a cross-sectional study. Clinical rheumatology 20110101
The alteration of asymmetric dimetilarginine (ADMA) levels in cardiac and gastrocnemius muscles following radioactive iodine application in guinea pigs and the effect of L-carnitine on this alteration. International journal of radiation biology 20110101
Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study. Clinical chemistry 20110101
Statin treatment decreased serum asymmetric dimethylarginine (ADMA) levels in ischemic stroke patients. Journal of atherosclerosis and thrombosis 20110101
Protection against age-dependent renal injury in the F344xBrown Norway male rat is associated with maintained nitric oxide synthase. Mechanisms of ageing and development 20110101
Association of asymmetric dimethylarginine with severity of kidney injury and decline in kidney function in IgA nephropathy. American journal of nephrology 20110101
Nitric oxide synthase inhibitors and cerebral vasospasm. Acta neurochirurgica. Supplement 20110101
Post-challenge hyperglycaemia, nitric oxide production and endothelial dysfunction: the putative role of asymmetric dimethylarginine (ADMA). Nutrition, metabolism, and cardiovascular diseases : NMCD 20110101
The effect of nebivolol on asymmetric dimethylarginine system in spontaneously hypertension rats. Vascular pharmacology 20110101
Pharmacological interventions on asymmetric dimethylarginine, a clinical marker of vascular disease. Current medicinal chemistry 20110101
L-arginine, NO and asymmetrical dimethylarginine in hypertension and type 2 diabetes. Frontiers in bioscience (Landmark edition) 20110101
The effect of nebivolol versus metoprolol succinate extended release on asymmetric dimethylarginine in hypertension. Journal of the American Society of Hypertension : JASH 20110101
3,4,5,6-Tetrahydroxyxanthone preserves intercellular communication by reduction of the endogenous nitric oxide synthase inhibitor level. Journal of Asian natural products research 20110101
Effect of asymmetric dimethylarginine on MIF expression and TNF-α and IL-8 secretion in THP-1 monocytes-derived macrophages. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110101
Effects of eicosapentaenoic acid on asymmetric dimethylarginine in patients in the chronic phase of cerebral infarction: a preliminary study. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20110101
Effects of asymmetric dimethylarginine on bovine retinal capillary endothelial cell proliferation, reactive oxygen species production, permeability, intercellular adhesion molecule-1, and occludin expression. Molecular vision 20110101
The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study. Cardiovascular diabetology 20110101
Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis. PloS one 20110101
Simvastatin re-couples dysfunctional endothelial nitric oxide synthase in experimental subarachnoid hemorrhage. PloS one 20110101
Contribution of endogenous inhibitor of nitric oxide synthase to hepatic mitochondrial dysfunction in streptozotocin-induced diabetic rats. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Lipid-apheresis improves microcirculation of the upper limbs. Journal of clinical apheresis 20110101
Serum asymmetric dimethylarginine and nitric oxide levels in obese postmenopausal women. Journal of clinical laboratory analysis 20110101
Production of free methylarginines via the proteasome and autophagy pathways in cultured cells. Molecular medicine reports 20110101
Meta-analysis of cardiovascular disease risk markers in women with polycystic ovary syndrome. Human reproduction update 20110101
Plasma asymmetric dimethylarginine levels in healthy people. Folia medica 20110101
Vascular incompetence in dialysis patients--protein-bound uremic toxins and endothelial dysfunction. Seminars in dialysis 20110101
Quantitation of L-arginine and asymmetric dimethylarginine in human plasma by LC-selective ion mode-MS for Type 2 diabetes mellitus study. Chemical & pharmaceutical bulletin 20110101
Asymmetric dimethylarginine (ADMA) levels display a morning peak in patients with acute myocardial infarction. Disease markers 20110101
Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice. Cardiovascular diabetology 20110101
Serum asymmetric dimethylarginine, nitrate, vitamin B(12), and homocysteine levels in individuals with pulmonary embolism. Mediators of inflammation 20110101
Simultaneous determination of L-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in the plasma of rodents with LC-MS/MS. Arzneimittel-Forschung 20110101
Actin cytoskeleton modulates ADMA-induced NF-kappaB nuclear translocation and ICAM-1 expression in endothelial cells. Medical science monitor : international medical journal of experimental and clinical research 20110101
Renovascular protective effects of erythropoietin in patients with chronic kidney disease. Internal medicine (Tokyo, Japan) 20110101
The transhepatic endotoxin gradient is present despite liver cirrhosis and is attenuated after transjugular portosystemic shunt (TIPS). BMC gastroenterology 20110101
The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia. Fetal and pediatric pathology 20110101
Endothelial dysfunction in the apolipoprotein E-deficient mouse: insights into the influence of diet, gender and aging. Lipids in health and disease 20110101
Diabetes and alpha lipoic Acid. Frontiers in pharmacology 20110101
Peripheral hemorheological and vascular correlates of coronary blood flow. Clinical hemorheology and microcirculation 20110101
Changes of skin temperature of parts of the body and serum asymmetric dimethylarginine (ADMA) in type-2 diabetes mellitus Indian patients. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20110101
Exploring disease activity and cardiovascular events by raised serum asymmetric dimethyl arginine among systemic lupus erythematosus patients. The Egyptian journal of immunology 20110101
Assessment of the relationship between asymmetric dimethylarginine and severity of erectile dysfunction and coronary artery disease. International urology and nephrology 20101201
Effect of supplementation with B vitamins and antioxidants on levels of asymmetric dimethylarginine (ADMA) and C-reactive protein (CRP): a double-blind, randomised, factorial design, placebo-controlled trial. European journal of nutrition 20101201
Adipokines, endothelial dysfunction and nutritional status in peritoneal dialysis patients. Scandinavian journal of urology and nephrology 20101201
Relationship between L-arginine/asymmetric dimethylarginine, homocysteine, folic acid, vitamin B levels, and coronary artery ectasia. Coronary artery disease 20101201
Negative association of L-arginine methylation products with oocyte numbers. Human reproduction (Oxford, England) 20101201
Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma. American journal of physiology. Lung cellular and molecular physiology 20101201
Asymmetric dimethylarginine upregulates the expression of ACAT-1 in THP-1 macrophage-derived foam cells. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20101201
HPLC determination of plasma dimethylarginines: method validation and preliminary clinical application. Clinica chimica acta; international journal of clinical chemistry 20101111
Effects of angiotensin type 1 receptor blockade on arginine and ADMA synthesis and metabolic pathways in fawn-hooded hypertensive rats. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101
Impaired endothelial function and microvascular asymmetrical dimethylarginine in angiotensin II-infused rats: effects of tempol. Hypertension (Dallas, Tex. : 1979) 20101101
Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats. Journal of pineal research 20101101
Serum asymmetric dimethylarginine levels in normotensive obese individuals. Medical science monitor : international medical journal of experimental and clinical research 20101101
Interethnic differences in ADMA concentrations and negative association with nitric oxide formation in preeclampsia. Clinica chimica acta; international journal of clinical chemistry 20101009
Association of homocysteine, asymmetric dimethylarginine, and nitric oxide with preeclampsia. Archives of gynecology and obstetrics 20101001
Effects of long-term disease-modifying antirheumatic drugs on endothelial function in patients with early rheumatoid arthritis. Cardiovascular therapeutics 20101001
Reduced proteinuria using ramipril in diabetic CKD stage 1 decreases circulating cell death receptor activators concurrently with ADMA. A novel pathophysiological pathway? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101001
Relationships between dimethylarginine and the presence of vertebral fractures in type 2 diabetes mellitus. Clinical endocrinology 20101001
FGF-23 and vascular dysfunction in patients with stage 3 and 4 chronic kidney disease. Kidney international 20101001
Antiretrovirals induce endothelial dysfunction via an oxidant-dependent pathway and promote neointimal hyperplasia. Toxicological sciences : an official journal of the Society of Toxicology 20101001
Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study. Atherosclerosis 20101001
Usefulness of cardiovascular biomarkers and cardiac imaging in systemic rheumatic diseases. Autoimmunity reviews 20101001
Do sea stars have low ADMA levels? High ADMA and low EPC count--duo infernal for the kidney. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101001
Circulating levels of asymmetric dimethylarginine are an independent risk factor for left ventricular hypertrophy and predict cardiovascular events in pre-dialysis patients with chronic kidney disease. European journal of internal medicine 20101001
The adipose tissue gene expression in mice with different nitric oxide availability. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20101001
Simultaneous quantitative determination of N(G),N(G)-dimethyl-L-arginine or asymmetric dimethylarginine and related pathway's metabolites in biological fluids by ultrahigh-performance liquid chromatography/electrospray ionization-tandem mass spectrometry. Analytica chimica acta 20100916
The effects of G-CSF-induced mobilization of progenitor cells are limited by ADMA. International journal of cardiology 20100903
ADMA is a correlate of insulin resistance in early-stage diabetes independent of hs-CRP and body adiposity. Annales d'endocrinologie 20100901
Left atrial volume and N-terminal pro-B type natriuretic peptide are associated with elevated pulmonary artery pressure in patients with systemic sclerosis. Clinical rheumatology 20100901
Modulatory role of the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine (ADMA), in morphine tolerance and dependence in mice. Journal of neural transmission (Vienna, Austria : 1996) 20100901
Angiotensin II and NADPH oxidase increase ADMA in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979) 20100901
Impact of reversible myocardial ischaemia on nitric oxide and asymmetric dimethylarginine production in patients with high risk for coronary heart disease. Medical science monitor : international medical journal of experimental and clinical research 20100901
The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism. Cell cycle (Georgetown, Tex.) 20100901
Sequential change of asymmetric dimethylarginine levels after initiation of peritoneal dialysis in patients with end-stage renal disease. Nephrology (Carlton, Vic.) 20100901
[Plasma asymmetric dimethylarginine and cystatin C levels in patients with coronary artery disease]. Zhonghua xin xue guan bing za zhi 20100901
Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics. Toxicology and applied pharmacology 20100815
Alpha-lipoic acid activates dimethylarginine dimethylaminohydrolase in cultured endothelial cells. Biochemical and biophysical research communications 20100806
Synergistic effects of asymmetrical dimethyl-L-arginine accumulation and endothelial progenitor cell deficiency on renal function decline during a 2-year follow-up in stable angina. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100801
The serum protein and lipid oxidation marker levels in Alzheimer's disease and effects of cholinesterase inhibitors and antipsychotic drugs therapy. Current Alzheimer research 20100801
Circulating angiopoietin-2 levels increase with progress of chronic kidney disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100801
The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: Relation with endothelial ADMA levels. Atherosclerosis 20100801
Asymmetric dimethylarginine correlates with measures of disease severity, major adverse cardiovascular events and all-cause mortality in patients with peripheral arterial disease. Vascular medicine (London, England) 20100801
Endothelium-derived vasoactive factors and hypertension: possible roles in pathogenesis and as treatment targets. Current hypertension reports 20100801
Bile duct ligation in developing rats: temporal progression of liver, kidney, and brain damage. Journal of pediatric surgery 20100801
Effect of selected drugs on plasma asymmetric dimethylarginine (ADMA) levels. Die Pharmazie 20100801
Asymmetric dimethylarginine concentrations are elevated in women with gestational diabetes. Endocrine 20100801
[The correlation of asymmetrical dimethylarginine level and oxidative stress to the onset of Alzheimer's disease]. Yao xue xue bao = Acta pharmaceutica Sinica 20100801
Endothelial dysfunction, ADMA and insulin resistance in essential hypertension. International journal of cardiology 20100723
Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism. Circulation research 20100709
A miR-thless perspective: how asymmetric dimethylarginine impairs the functions of angiogenic progenitor cells. Circulation research 20100709
Effect of genistein therapy on plasma levels of asymmetric dimethylarginine in healthy postmenopausal women: a randomized, placebo-controlled study. Fertility and sterility 20100701
Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine in the rat aorta. British journal of pharmacology 20100701
Predictors of the intima-media thickness of carotid artery in asymptomatic newly detected severe hypercholesterolemic patients. Clinical physiology and functional imaging 20100701
The effects of endothelial dysfunction and inflammation on slow coronary flow. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20100701
The beneficial effects of angiotensin-converting enzyme inhibitors on serum asymmetric dimethylarginine levels in the patients with cardiovascular disease. International journal of cardiology 20100625
Massive quantities of asymmetric dimethylarginine (ADMA) are incorporated in red blood cell proteins and may be released by proteolysis following hemolytic stress. Blood cells, molecules & diseases 20100615
Acute effects of 5-methyltetrahydrofolate on endothelial function and asymmetric dimethylarginine in patients with chronic heart failure. Nutrition, metabolism, and cardiovascular diseases : NMCD 20100601
ADMA, C-reactive protein, and albuminuria in untreated essential hypertension: a cross-sectional study. American journal of kidney diseases : the official journal of the National Kidney Foundation 20100601
Adenoviral-mediated overexpression of DDAH improves vascular tone regulation. Vascular medicine (London, England) 20100601
Randomized controlled trial of the effect of short-term coadministration of methylcobalamin and folate on serum ADMA concentration in patients receiving long-term hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation 20100601
Association between exaggerated blood pressure response to exercise and serum asymmetric dimethylarginine levels. Circulation journal : official journal of the Japanese Circulation Society 20100601
Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and plasma concentrations of asymmetric dimethylarginine in Turkish pre-eclamptic women without fetal growth retardation. The journal of obstetrics and gynaecology research 20100601
Chitotriosidase activity predicts endothelial dysfunction in type-2 diabetes mellitus. Endocrine 20100601
Asymmetric dimethylarginine (ADMA) is present in plasma proteins of healthy subjects at the low nmol-per-g-level. Nitric oxide : biology and chemistry 20100515
Early detection of cardiac involvement in systemic sclerosis assessed by tissue-Doppler echocardiography: relationship with neurohormonal activation and endothelial dysfunction. The Journal of rheumatology 20100501
Nitric oxide and oxidative stress in vascular disease. Pflugers Archiv : European journal of physiology 20100501
Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine. The American journal of pathology 20100501
Plasma apelin and ADMA Levels in patients with essential hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993) 20100501
Neuroprotective effect of asymmetric dimethylarginine against 1-methyl-4-phenylpyridinium ion-induced damage in PC12 cells. Clinical and experimental pharmacology & physiology 20100501
The role of the DDAH-ADMA pathway in the protective effect of resveratrol analog BTM-0512 on gastric mucosal injury. Canadian journal of physiology and pharmacology 20100501
Asymmetric dimethylarginine in hemodialysis, hemodiafiltration, and peritoneal dialysis. Artificial organs 20100501
The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease. Current cardiology reviews 20100501
Plasma asymmetric dimethylarginine concentrations in sickle cell disease are related to the hemolytic phenotype. Blood cells, molecules & diseases 20100415
A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease. Circulation research 20100402
Down but not out: candidate gene-based studies still have value in a world dominated by whole genome approaches. Circulation research 20100402
Increased nitric oxide stress is associated with migraine. Cephalalgia : an international journal of headache 20100401
Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus. Journal of thrombosis and haemostasis : JTH 20100401
Intake of red wine increases the number and functional capacity of circulating endothelial progenitor cells by enhancing nitric oxide bioavailability. Arteriosclerosis, thrombosis, and vascular biology 20100401
Inflammatory/oxidative stress during the first week after different types of cardiac surgery. Scandinavian cardiovascular journal : SCJ 20100401
Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase. Journal of hypertension 20100401
Effects of stent implementation on plasma levels of asymmetric dimethylarginine in patients with or without ST-segment elevation acute myocardial infarction. International journal of molecular medicine 20100401
Melatonin prevents increased asymmetric dimethylarginine in young rats with bile duct ligation. Journal of pineal research 20100401
Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus. Diabetes & vascular disease research 20100401
Correlation between plasma asymmetric dimethylarginine and different types of coronary heart disease. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100401
Effect of uric acid on coronary microvascular endothelial function in women: association with eGFR and ADMA. Journal of atherosclerosis and thrombosis 20100331
Asymmetric dimethylarginine (ADMA) as a possible risk marker for ischemic stroke. Journal of the neurological sciences 20100315
Arginine methylation of vasa protein is conserved across phyla. The Journal of biological chemistry 20100312
Asymmetric dimethylarginine levels and carotid intima-media thickness in obese patients with polycystic ovary syndrome and their relationship to metabolic parameters. Fertility and sterility 20100301
Ex vivo gene transferring of human dimethylarginine dimethylaminohydrolase-2 improved endothelial dysfunction in diabetic rat aortas and high glucose-treated endothelial cells. Atherosclerosis 20100301
Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians. European journal of endocrinology 20100301
Circulating methylarginine levels and the decline in renal function in patients with chronic kidney disease are modulated by DDAH1 polymorphisms. Kidney international 20100301
Asymmetric dimethylarginine in angiotensin II-induced hypertension. American journal of physiology. Regulatory, integrative and comparative physiology 20100301
Green tea catechins improve human forearm endothelial dysfunction and have antiatherosclerotic effects in smokers. Circulation journal : official journal of the Japanese Circulation Society 20100301
Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production. The Journal of biological chemistry 20100219
Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. Circulation research 20100219
ADMA concentration changes across the menstrual cycle and during oral contraceptive use: the Cardiovascular Risk in Young Finns Study. European journal of endocrinology 20100201
Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. The Journal of urology 20100201
Asymmetric dimethylarginine, an endogenous NO synthase inhibitor, in human breast milk. Early human development 20100201
Endothelial function and insulin resistance in polycystic ovary syndrome: the effects of medical therapy. Fertility and sterility 20100101
Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA), arginine, and 8-iso-prostaglandin F2alpha (8-iso-PGF2alpha) level in patients with inflammatory bowel diseases. Inflammatory bowel diseases 20100101
The conjoint detrimental effect of chronic periodontal disease and systemic inflammation on asymmetric dimethyl-arginine in untreated hypertensive subjects. Atherosclerosis 20100101
Altered asymmetric dimethyl arginine metabolism in allergically inflamed mouse lungs. American journal of respiratory cell and molecular biology 20100101
Co-administration of ezetimibe enhances proteinuria-lowering effects of pitavastatin in chronic kidney disease patients partly via a cholesterol-independent manner. Pharmacological research 20100101
Collagen synthesis, nitric oxide and asymmetric dimethylarginine in diabetic subjects undergoing hyperbaric oxygen therapy. Physiological research 20100101
Altered metabolisms of mediators controlling vascular function and enhanced oxidative stress in asymptomatic children with congenital portosystemic venous shunt. Metabolism: clinical and experimental 20100101
Postprandial vascular effects of VIAject compared with insulin lispro and regular human insulin in patients with type 2 diabetes. Diabetes care 20100101
The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia. Gynecologic and obstetric investigation 20100101
Asymmetrical dimethylarginine is associated with renal and cardiovascular outcomes and all-cause mortality in renal transplant recipients. Kidney international 20100101
Distribution of asymmetric dimethylarginine among 980 healthy, older adults of different ethnicities. Clinical chemistry 20100101
Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2. American journal of physiology. Heart and circulatory physiology 20100101
Stroke biomarkers: progress and challenges for diagnosis, prognosis, differentiation, and treatment. Clinical chemistry 20100101
The biochemistry, measurement and current clinical significance of asymmetric dimethylarginine. Annals of clinical biochemistry 20100101
Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: role of asymmetric dimethylarginine. Vascular pharmacology 20100101
Increased serum asymmetric dimethylarginine levels in primary dysmenorrhea. Gynecologic and obstetric investigation 20100101
Association between plasma asymmetrical dimethylarginine activity and saphenous vein graft disease in patients with coronary bypass. Coronary artery disease 20100101
Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus. Translational research : the journal of laboratory and clinical medicine 20100101
Growth differentiation factor 15 and coronary collateral formation. Clinical cardiology 20100101
A novel predictor of restenosis and adverse cardiac events: asymmetric dimethylarginine. Heart and vessels 20100101
Increased levels of asymmetric dimethylarginine and C-reactive protein are associated with impaired vascular reactivity in essential hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101
Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes. PloS one 20100101
The effect of n-3 fatty acids on levels of methylarginines in patients with end-stage renal disease. Journal of nephrology 20100101
Perspectives in renal disease progression: the endothelium as a treatment target in chronic kidney disease. Journal of nephrology 20100101
New pathways to renal damage: role of ADMA in retarding renal disease progression. Journal of nephrology 20100101
Effect of simvastatin on nitric oxide synthases (eNOS, iNOS) and arginine and its derivatives (ADMA, SDMA) in ischemia/reperfusion injury in rat liver. Pharmacological reports : PR 20100101
[Prevalence of cardiovascular disease in uraemia and relevance of cardiovascular risk factors]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101
Cardiovascular disease markers in women with polycystic ovary syndrome with emphasis on asymmetric dimethylarginine and homocysteine. Annals of Saudi medicine 20100101
The levels of asymmetric dimethylarginine in patients with isolated coronary artery ectasia. Annals of Saudi medicine 20100101
Hormone therapy and asymmetrical dimethylarginine in postmenopausal women. Hormones (Athens, Greece) 20100101
The differences of asymmetric dimethylarginine removal by different dialysis treatments. Renal failure 20100101
Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension. Vascular pharmacology 20100101
Relationship between asymmetric dimethylarginine and asymptomatic carotid atherosclerosis. Journal of biological regulators and homeostatic agents 20100101
Simvastatin and asymmetric dimethylarginine-homocysteine metabolic pathways in patients with newly detected severe hypercholesterolemia. Clinical laboratory 20100101
[Asymmetric dimethylarginine (ADMA) in children with diabetes type 1]. Pediatric endocrinology, diabetes, and metabolism 20100101
Helicobacter pylori eradication lowers serum asymmetric dimethylarginine levels. Mediators of inflammation 20100101
The biology and therapeutic potential of the DDAH/ADMA pathway. Current pharmaceutical design 20100101
Acute effects of hyperglycaemia on asymmetric dimethylarginine (ADMA), adiponectin and inflammatory markers (IL-6, hs-CRP) in overweight and obese women with metabolic syndrome. British journal of biomedical science 20100101
Effect of aspirin on high glucose-induced senescence of endothelial cells. Chinese medical journal 20091220
Circulating asymmetric dimethylarginine, endothelin-1 and cell adhesion molecules in women with gestational diabetes. Acta diabetologica 20091201
Ezetimibe decreases serum levels of asymmetric dimethylarginine (ADMA) and ameliorates renal injury in non-diabetic chronic kidney disease patients in a cholesterol-independent manner. Pharmacological research 20091201
Circulating levels of advanced glycation end products (AGE) and interleukin-6 (IL-6) are independent determinants of serum asymmetric dimethylarginine (ADMA) levels in patients with septic shock. Pharmacological research 20091201
Methylarginines and mortality in patients with end stage renal disease: a prospective cohort study. Atherosclerosis 20091201
The effect of rosiglitazone on asymmetric dimethylarginine (ADMA) in critically ill patients. Pharmacological research 20091201
Correlates of arterial stiffness in an ageing population: role of asymmetric dimethylarginine. Pharmacological research 20091201
Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality--an update on patient populations with a wide range of cardiovascular risk. Pharmacological research 20091201
Plasma concentrations of the cardiovascular risk factor asymmetric dimethylarginine (ADMA) are increased in patients with HIV-1 infection and correlate with immune activation markers. Pharmacological research 20091201
ADMA and the role of the genes: lessons from genetically modified animals and human gene polymorphisms. Pharmacological research 20091201
Cellular ADMA: regulation and action. Pharmacological research 20091201
Role of the PRMT-DDAH-ADMA axis in the regulation of endothelial nitric oxide production. Pharmacological research 20091201
PRMT-1 and DDAHs-induced ADMA upregulation is involved in ROS- and RAS-mediated diabetic retinopathy. Experimental eye research 20091201
The ADMA/DDAH pathway regulates VEGF-mediated angiogenesis. Arteriosclerosis, thrombosis, and vascular biology 20091201
Role of asymmetric-dimethyl-L-arginine (ADMA) and nitrite/nitrate (NOx) in the pathogenesis of oxidative stress in female subjects with uncomplicated type 1 diabetes mellitus. Diabetes research and clinical practice 20091201
Asymmetric dimethylarginine: understanding the physiology, genetics, and clinical relevance of this novel biomarker. Proceedings of the 4th International Symposium on ADMA. Pharmacological research 20091201
The DDAH/ADMA pathway in the control of endothelial cell migration and angiogenesis. Biochemical Society transactions 20091201
Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1-deficient mice reveal that vascular endothelium plays an important role in removing asymmetric dimethylarginine. Circulation 20091201
Asymmetric dimethylarginine damages connexin43-mediated endothelial gap junction intercellular communication. Biochemistry and cell biology = Biochimie et biologie cellulaire 20091201
Serum ADMA concentration-- an independent factor determining FMD impairment in cardiac syndrome X. Upsala journal of medical sciences 20091201
The DDAH-ADMA pathway. Proceedings of the 4th International Symposium on ADMA. August 28-30, 2008. Bregenz, Austria. Pharmacological research 20091201
Dimethylarginines and serotonin in the blood of spontaneously hypertensive rats. Bulletin of experimental biology and medicine 20091201
Positive association of serum levels of advanced glycation end products and high mobility group box-1 with asymmetric dimethylarginine in nondiabetic chronic kidney disease patients. Metabolism: clinical and experimental 20091101
Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate. Pediatric research 20091101
Is asymmetric dimethylarginine responsible for the vascular events in patients under antiepileptic drug treatment? Epilepsy research 20091101
A click chemistry mediated in vivo activity probe for dimethylarginine dimethylaminohydrolase. Journal of the American Chemical Society 20091028
Postmenopausal women with osteoporosis may be associated with high endothelin-1. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20091001
Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia. Pediatric research 20091001
Coordinated regulation of dimethylarginine dimethylaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine. The Journal of pharmacology and experimental therapeutics 20091001
Quantification of arginine and its mono- and dimethylated analogs NMMA, ADMA and SDMA in biological fluids by LC-MS/MS: Is LC superfluous? Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001
Paradoxical effect of L-arginine: acceleration of endothelial cell senescence. Biochemical and biophysical research communications 20090904
Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity. Neurochemical research 20090901
Differential effects of cross-sex hormonal treatment on plasma asymmetric dimethylarginine (ADMA) in healthy male-to-female and female-to-male transsexuals. Atherosclerosis 20090901
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition. Arteriosclerosis, thrombosis, and vascular biology 20090901
Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study. Stroke 20090901
Effect of keto acids on asymmetric dimethylarginine, muscle, and fat tissue in chronic kidney disease and after kidney transplantation. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20090901
Asymmetric dimethylarginine endogenous inhibition of nitric oxide synthase causes differential vasculature effects. Medical science monitor : international medical journal of experimental and clinical research 20090901
Role of neutrophils in arginine-asymmetric dimethylarginine pathway subsequent to endotoxemia. Annals of the New York Academy of Sciences 20090901
Asymmetric dimethylarginine induces tissue factor expression in monocytes via NF-kappaB-dependent pathway: Role in acute coronary syndromes. Atherosclerosis 20090801
De novo synthesis of trideuteromethyl esters of amino acids for use in GC-MS and GC-tandem MS exemplified for ADMA in human plasma and urine: standardization, validation, comparison and proof of evidence for their aptitude as internal standards. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090801
ADMA and SDMA levels in healthy men exposed to tobacco smoke. Atherosclerosis 20090801
Ranolazine improves endothelial function in patients with stable coronary artery disease. Coronary artery disease 20090801
Inhibition of natriuretic factors increases blood pressure in rats. American journal of physiology. Renal physiology 20090801
Asymmetric dimethylarginine reference intervals determined with liquid chromatography-tandem mass spectrometry: results from the Framingham offspring cohort. Clinical chemistry 20090801
Renal resistance index in renal allograft recipients: a role for ADMA. American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801
Determinants of occurrence of aortic sclerosis in an aging population. JACC. Cardiovascular imaging 20090801
Prophylactics of erectile dysfunction in patients with metabolic syndrome. Bulletin of experimental biology and medicine 20090801
Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population. Atherosclerosis 20090701
Non-invasive assessment of coronary flow reserve and ADMA levels: a case-control study of early rheumatoid arthritis patients. Rheumatology (Oxford, England) 20090701
Proteomic identification of cytosolic proteins that undergo arginine methylation during rat liver regeneration. Electrophoresis 20090701
Involvement of asymmetric dimethylarginine (ADMA) in glomerular capillary loss and sclerosis in a rat model of chronic kidney disease (CKD). Life sciences 20090605
Carotid intima-media thickness in patients with cardiac syndrome X and its association with high circulating levels of asymmetric dimethylarginine. Atherosclerosis 20090601
Asymmetric dimethylarginine is closely associated with the development and progression of nephropathy in patients with type 2 diabetes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601
ADMA injures the glomerular filtration barrier: role of nitric oxide and superoxide. American journal of physiology. Renal physiology 20090601
HDL-cholesterol, blood pressure, and asymmetric dimethylarginine are significantly associated with arterial wall thickness in children. Arteriosclerosis, thrombosis, and vascular biology 20090601
Low arginine/asymmetric dimethylarginine ratio deteriorates systemic hemodynamics and organ blood flow in a rat model. Critical care medicine 20090601
Asymmetric dimethylarginine and mortality in stages 3 to 4 chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN 20090601
Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension. Journal of hypertension 20090601
[Effects of Xuefu Zhuyu decoction on serum asymmetric dimethylarginine in atherosclerosis rabbits]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090601
Plasma asymmetric dimethylarginine, L-arginine and left ventricular structure and function in a community-based sample. Atherosclerosis 20090501
Role of symmetric dimethylarginine in vascular damage by increasing ROS via store-operated calcium influx in monocytes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090501
Losartan inhibits monocytic adhesion induced by ADMA via downregulation of chemokine receptors in monocytes. European journal of clinical pharmacology 20090501
Maternal serum ADMA is not associated with proinflammatory cytokines or C-reactive protein during normal pregnancy. Cytokine 20090501
Asymmetric dimethylarginine and nitric oxide levels in migraine during the interictal period. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090501
Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis. European heart journal 20090501
Correlation of biomarkers of endothelium dysfunction and matrix remodeling in patients with systemic sclerosis. The Journal of rheumatology 20090501
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death. British journal of haematology 20090501
Stent placement in patients with coronary heart disease decreases plasma levels of the endogenous nitric oxide synthase inhibitor ADMA. International journal of molecular medicine 20090501
[Biology of arterial ageing and arteriosclerosis]. Comptes rendus biologies 20090501
Asymmetric dimethylarginine (ADMA) and endothelial dysfunction: implications for atherogenesis. Clinics (Sao Paulo, Brazil) 20090501
L-Arginine is related to endothelium-dependent vasodilation in resistance and conduit arteries in divergent ways-The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Atherosclerosis 20090401
Involvement of asymmetric dimethylarginine (ADMA) in tubulointerstitial ischaemia in the early phase of diabetic nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401
Advanced oxidative protein products are independently associated with endothelial function in peritoneal dialysis patients. Nephrology (Carlton, Vic.) 20090401
Endothelial and red blood cell turnover rate--factors possibly affecting circulating ADMA levels? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401
Asymmetrical dimethylarginine triggers lipolysis and inflammatory response via induction of endoplasmic reticulum stress in cultured adipocytes. American journal of physiology. Endocrinology and metabolism 20090401
Determinants of platelet activation in hypertensives with microalbuminuria. Free radical biology & medicine 20090401
Asymmetric dimethylarginine (ADMA): an endogenous inhibitor of nitric oxide synthase and a novel cardiovascular risk molecule. Medical science monitor : international medical journal of experimental and clinical research 20090401
Elevation of serum apelin-13 is positively correlated with ADMA in patients on maintenance hemodialysis. Clinical nephrology 20090401
Vascular biomarkers in the metabolic syndrome. Expert review of molecular diagnostics 20090401
Serum asymmetric dimethylarginine and endothelial function after renal transplantation. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090401
[Relationship between changes of endogenous nitric oxide synthase inhibitor and hydrolase and initiation of pre-eclampsia]. Zhonghua fu chan ke za zhi 20090401
Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community. Circulation 20090331
Plasma levels of asymmetric dimethylarginine in premature neonates: its possible involvement in developmental programming of chronic diseases. Acta paediatrica (Oslo, Norway : 1992) 20090301
HPLC analysis of asymmetric dimethylarginine (ADMA) and related arginine metabolites in human plasma using a novel non-endogenous internal standard. Clinica chimica acta; international journal of clinical chemistry 20090301
Asymmetric dimethylarginine predicts outcome and time of stay in hospital in patients attending an internal medicine emergency room. Clinica chimica acta; international journal of clinical chemistry 20090301
Evaluation of asymmetric dimethylarginine and homocysteine in microangiopathy-related cerebral damage. American journal of hypertension 20090301
Plasma asymmetric dimethylarginine is related to anticitrullinated protein antibodies in rheumatoid arthritis of short duration. Metabolism: clinical and experimental 20090301
ADMA and the brain: an unfolding story. American journal of hypertension 20090301
Relationship of baseline plasma ADMA levels to cardiovascular outcomes at 2 years in men with acute coronary syndrome referred for coronary angiography. Coronary artery disease 20090301
Dimethylarginine dimethylaminohydrolase regulation: a novel therapeutic target in cardiovascular disease. Expert opinion on drug metabolism & toxicology 20090301
Effect of angiotensin-converting enzyme inhibitor on serum asymmetric dimethylarginine and coronary circulation in patients with type 2 diabetes mellitus. International journal of cardiology 20090220
Asymmetric dimethylarginine and impaired cardiovascular healing. Journal of thrombosis and thrombolysis 20090201
Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension. American journal of physiology. Regulatory, integrative and comparative physiology 20090201
Blood content of asymmetric dimethylarginine: new insights into its dysregulation in renal disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201
Acute effects of Helicobacter pylori extracts on gastric mucosal blood flow in the mouse. World journal of gastroenterology 20090114
Asymmetric dimethylarginine and the effect of folate substitution in children with familial hypercholesterolemia and diabetes mellitus type 1. Physiological research 20090101
Relationship between serum pre-B cell colony-enhancing factor/visfatin and atherosclerotic parameters in chronic hemodialysis patients. American journal of nephrology 20090101
Obstructive sleep apnoea syndrome is associated with enhanced sub-clinical inflammation and asymmetric dimethyl-arginine levels in hypertensives. Journal of human hypertension 20090101
Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101
Elevated plasma adiponectin and decreased plasma homocysteine and asymmetric dimethylarginine in children with type 1 diabetes. Scandinavian journal of clinical and laboratory investigation 20090101
Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function. Molecular biology of the cell 20090101
Increased plasma levels of asymmetric dimethylarginine and soluble CD40 ligand in patients with sleep apnea. Respiration; international review of thoracic diseases 20090101
Unchanged plasma levels of dimethylarginines and nitric oxide in chronic hepatitis C. Scandinavian journal of gastroenterology 20090101
Plasma ADMA predicts restenosis of arteriovenous fistula. Journal of the American Society of Nephrology : JASN 20090101
Clinical implications of elevated asymmetric dimethylarginine in chronic kidney disease and end-stage renal disease. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20090101
From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases. BMC pulmonary medicine 20090101
The impact of fiber supplementation on ADMA levels. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20090101
Telmisartan decreases plasma levels of asymmetrical dimethyl-L-arginine and improves lipid and glucose metabolism and vascular function. International heart journal 20090101
Relationship between cerebral arterial pulsatility and carotid intima media thickness in diabetic and non-diabetic patients with non-alcoholic fatty liver disease. Journal of endocrinological investigation 20090101
Posttranslational modification of constitutive nitric oxide synthase in the penis. Journal of andrology 20090101
Perinatal risk factors affecting the maternal and fetal asymmetric dimethylarginine levels. The Turkish journal of pediatrics 20090101
A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria. Cardiovascular diabetology 20090101
Asymmetric dimethylarginine impairs glucose utilization via ROS/TLR4 pathway in adipocytes: an effect prevented by vitamin E. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101
Increased levels of asymmetric dimethylarginine (ADMA) in patients with ankylosing spondylitis. Internal medicine (Tokyo, Japan) 20090101
Asymmetric dimethylarginine and symmetric dimethylarginine: axis of evil or useful alliance? Seminars in dialysis 20090101
The emerging role of symmetric dimethylarginine in vascular disease. Advances in clinical chemistry 20090101
Dimethylarginine dimethylaminohydrolase-1 transgenic mice are not protected from ischemic stroke. PloS one 20090101
Asymmetric dimethylarginine, vascular calcifications and parathyroid hormone serum levels in hemodialysis patients. Journal of nephrology 20090101
Dimethylarginine levels and nutritional status in hemodialysis patients. Journal of nephrology 20090101
Effects of an exercise intervention using Dance Dance Revolution on endothelial function and other risk factors in overweight children. International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity 20090101
[Homocysteine and asymmetric dimethylarginine (ADMA) in epilepsy]. Przeglad lekarski 20090101
Transjugular intrahepatic portosystemic shunt-placement increases arginine/asymmetric dimethylarginine ratio in cirrhotic patients. World journal of gastroenterology 20081221
ADMA, cardiovascular disease and diabetes. Diabetes research and clinical practice 20081215
Effect of acute variations of insulin and glucose on plasma concentrations of asymmetric dimethylarginine in young people with Type 1 diabetes. Clinical science (London, England : 1979) 20081201
Endogenous nitric oxide synthase inhibitors, arterial hemodynamics, and subclinical vascular disease: the PREVENCION Study. Hypertension (Dallas, Tex. : 1979) 20081201
Roles of oxidants, nitric oxide, and asymmetric dimethylarginine in endothelial function. Journal of cardiovascular pharmacology and therapeutics 20081201
Smoker's paradox in heart failure: might asymmetric dimethylarginine be the possible explanation? European heart journal 20081201
Plasma ADMA concentrations at birth and mechanical ventilation in preterm infants: a prospective pilot study. Pediatric pulmonology 20081201
Effects of growth hormone treatment on arginine to asymmetric dimethylarginine ratio and endothelial function in patients with growth hormone deficiency. Metabolism: clinical and experimental 20081201
Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension. American heart journal 20081201
Asymmetric dimethylarginine in hematological malignancies: a preliminary study. Leukemia & lymphoma 20081201
Nebivolol treatment reduces serum levels of asymmetric dimethylarginine and improves endothelial dysfunction in essential hypertensive patients. American journal of hypertension 20081101
Development and validation of a fast quantitative method for plasma dimethylarginines analysis using liquid chromatography-tandem mass spectrometry. Clinical biochemistry 20081101
Relationship of asymmetric dimethylarginine with flow-mediated dilatation in subjects with newly detected severe hypercholesterolemia. Clinical physiology and functional imaging 20081101
Nitric oxide upregulates dimethylarginine dimethylaminohydrolase-2 via cyclic GMP induction in endothelial cells. Hypertension (Dallas, Tex. : 1979) 20081101
ADMA impairs nitric oxide-mediated arteriolar function due to increased superoxide production by angiotensin II-NAD(P)H oxidase pathway. Hypertension (Dallas, Tex. : 1979) 20081101
Asymmetric dimethylarginine and coronary collateral vessel development. Coronary artery disease 20081101
Asymmetric dimethylarginine levels decrease because of insulin infusion: is it an unexpected finding? Metabolism: clinical and experimental 20081101
Asymmetric dimethylarginine: a novel marker of risk and a potential target for therapy in chronic kidney disease. Current opinion in nephrology and hypertension 20081101
Decrease in the synthesis and release of calcitonin gene-related peptide in dorsal root ganglia of spontaneously hypertensive rat: role of nitric oxide synthase inhibitors. European journal of pharmacology 20081031
Metformin and oral contraceptive treatments reduced circulating asymmetric dimethylarginine (ADMA) levels in patients with polycystic ovary syndrome (PCOS). Atherosclerosis 20081001
Alpha-defensin-like product and asymmetric dimethylarginine increase in mesenteric lymph after hemorrhage in anesthetized rat. Shock (Augusta, Ga.) 20081001
Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
Asymmetric dimethylarginine (ADMA) is tightly correlated with growth in juveniles without correlations to obesity related disorders. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20081001
Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide. British journal of pharmacology 20081001
Down-regulation of asymmetric arginine methylation during replicative and H2O2-induced premature senescence in WI-38 human diploid fibroblasts. Journal of biochemistry 20081001
Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation. Clinical biochemistry 20081001
Increased asymmetric dimethylarginine levels in young men with familial Mediterranean fever (FMF): is it early evidence of interaction between inflammation and endothelial dysfunction in FMF? The Journal of rheumatology 20081001
Effect of nitrous oxide anesthesia on plasma homocysteine and endothelial function. Anesthesiology 20081001
L-arginine analogs--inactive markers or active agents in atherogenesis? Cardiovascular & hematological agents in medicinal chemistry 20081001
Sodium, hypertension, and an explanation of the 'lag phenomenon' in hemodialysis patients. Hemodialysis international. International Symposium on Home Hemodialysis 20081001
Methylated arginines in stable and acute patients with coronary artery disease before and after percutaneous revascularization. International journal of cardiology 20080926
Coronary artery calcification, ADMA, and insulin resistance in CKD patients. Clinical journal of the American Society of Nephrology : CJASN 20080901
EPO induces rise in serum ADMA but does not prevent the increase in NO release: the likely involvement of HO-1. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901
Association of asymmetric dimethylarginine with sickle cell disease-related pulmonary hypertension. Haematologica 20080901
Determination of asymmetric dimethylarginine in biological fluids: a paradigm for a successful analytical story. Current opinion in clinical nutrition and metabolic care 20080901
Cardiovascular disease in patients with diabetic nephropathy. Current molecular medicine 20080901
[Endothelial injury and CKD]. Nihon rinsho. Japanese journal of clinical medicine 20080901
Asymmetric dimethylarginine (ADMA) and other endogenous nitric oxide synthase (NOS) inhibitors as an important cause of vascular insulin resistance. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080901
[The effect of plasma asymmetric dimethylarginine (ADMA) level and L-arginine/ADMA ratio on the development of coronary collaterals]. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20080901
Metformin, arterial function, intima-media thickness and nitroxidation in metabolic syndrome: the mefisto study. Clinical and experimental pharmacology & physiology 20080801
Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study. American journal of hypertension 20080801
Symmetric dimethylarginine is an independent predictor of intradialytic hypotension. American journal of hypertension 20080801
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia. American journal of physiology. Heart and circulatory physiology 20080801
Asymmetric dimethylarginine concentration and early recurrence of atrial fibrillation after electrical cardioversion. Pacing and clinical electrophysiology : PACE 20080801
[Pathophysiology of mild hypertension: role of endothelial function]. Nihon rinsho. Japanese journal of clinical medicine 20080801
Regulation of eNOS-derived superoxide by endogenous methylarginines. Biochemistry 20080708
Plasma concentrations of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, are elevated in sickle cell patients but do not increase further during painful crisis. American journal of hematology 20080701
Disturbed angiogenesis in systemic sclerosis: high levels of soluble endoglin. Rheumatology (Oxford, England) 20080701
Plasma asymmetric dimethylarginine and cardiovascular events in patients with acute decompensated heart failure. Translational research : the journal of laboratory and clinical medicine 20080701
Differential long-term effects of carvedilol on proinflammatory and antiinflammatory cytokines, asymmetric dimethylarginine, and left ventricular function in patients with heart failure. Journal of cardiovascular pharmacology 20080701
Determination of dimethylarginine levels in rats using HILIC-MS/MS: an in vivo microdialysis study. Journal of separation science 20080701
Evaluation of mobile phase, ion pairing, and temperature influence on an HILIC-MS/MS method for L-arginine and its dimethylated derivatives detection. Journal of separation science 20080701
Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension. Circulation 20080610
Endothelin-1 and asymmetric dimethylarginine in children with left-to-right shunt after intracardiac repair. Clinical research in cardiology : official journal of the German Cardiac Society 20080601
Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: role of mitochondrial dysfunction. American journal of physiology. Cell physiology 20080601
Acute effects of passive smoking on peripheral vascular function. Hypertension (Dallas, Tex. : 1979) 20080601
Putative role of asymmetric dimethylarginine in microvascular disease of kidney and heart in hypertensive patients. American journal of hypertension 20080601
The homocysteine paradox. Arteriosclerosis, thrombosis, and vascular biology 20080601
Glomerular filtration and coronary flow: is ADMA the faucet regulating both? American journal of hypertension 20080601
Plasma level of asymmetric dimethylarginine (ADMA) as a predictor of carotid intima-media thickness progression: six-year prospective study using carotid ultrasonography. Hypertension research : official journal of the Japanese Society of Hypertension 20080601
[Asymmetric dimethil-arginine (ADMA) as a link between insulin resistance and atherosclerosis]. Ideggyogyaszati szemle 20080530
A new selective pre-column ninhydrin-based derivatization for a RP-HPLC determination of plasma asymmetric dimethyl-L-arginine (ADMA) by fluorescence detection. Amino acids 20080501
Human recombinant erythropoietin augments serum asymmetric dimethylarginine concentrations but does not compromise nitric oxide generation in mice. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080501
Impact of asymmetric dimethylarginine on mortality after acute myocardial infarction. Arteriosclerosis, thrombosis, and vascular biology 20080501
Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg. Arteriosclerosis, thrombosis, and vascular biology 20080501
Effects of moderate hyperhomocysteinaemia induced by 4 weeks methionine-enriched diet on metabolite profile and mesenteric artery function in rats. The British journal of nutrition 20080501
Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failure. European journal of heart failure 20080501
Short term fluvastatin treatment lowers serum asymmetric dimethylarginine levels in patients with metabolic syndrome. International heart journal 20080501
Gene transfer of dimethylarginine dimethylaminohydrolase-2 improves the impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells induced by lysophosphatidylcholine. European journal of pharmacology 20080414
Relations between markers of renal function, coronary risk factors and the occurrence and severity of coronary artery disease. Atherosclerosis 20080401
Methylglyoxal and methylglyoxal-arginine adducts do not directly inhibit endothelial nitric oxide synthase. Annals of the New York Academy of Sciences 20080401
Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity. Arteriosclerosis, thrombosis, and vascular biology 20080401
[The effect of plasma asymmetric dimethylarginine (ADMA) level and L-arginine/ADMA ratio on the development of coronary collaterals]. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20080401
Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus. Transplantation 20080327
Involvement of the endothelial DDAH/ADMA pathway in nitroglycerin tolerance: the role of ALDH-2. Life sciences 20080326
Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle? Clinical journal of the American Society of Nephrology : CJASN 20080301
Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging. Hypertension (Dallas, Tex. : 1979) 20080301
Biomarkers in acute and chronic kidney disease. Current opinion in nephrology and hypertension 20080301
Anti-hypertensive effects of Rosuvastatin are associated with decreased inflammation and oxidative stress markers in hypertensive rats. Free radical research 20080301
Role of endogenous nitric oxide synthase inhibitor in gastric mucosal injury. Canadian journal of physiology and pharmacology 20080301
Study of the correlation between clinical efficiency of impaza and serum ADMA level. Bulletin of experimental biology and medicine 20080301
The administration of estrogens, combined with anti-androgens, has beneficial effects on the hormonal features and asymmetric dimethyl-arginine levels, in women with the polycystic ovary syndrome. Atherosclerosis 20080201
Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals. American journal of physiology. Renal physiology 20080201
Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia. Clinical chemistry 20080201
Urotensin II and cardiomyopathy in end-stage renal disease. Hypertension (Dallas, Tex. : 1979) 20080201
Elevated asymmetric dimethylarginine (ADMA) and inverse correlation between circulating ADMA and glomerular filtration rate in children with sporadic focal segmental glomerulosclerosis (FSGS). Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080201
Synthetic approaches to N(delta)-methylated L-arginine, N(omega)-hydroxy-L-arginine, L-citrulline, and N(delta)-cyano-L-ornithine. The Journal of organic chemistry 20080201
Determination of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, in umbilical blood. Metabolism: clinical and experimental 20080201
ADMA levels correlate with proteinuria, secondary amyloidosis, and endothelial dysfunction. Journal of the American Society of Nephrology : JASN 20080201
Asymmetric dimethylarginine and lipid peroxidation products in early autosomal dominant polycystic kidney disease. American journal of kidney diseases : the official journal of the National Kidney Foundation 20080201
First-trimester uterine artery resistance and maternal serum concentration of asymmetric dimethylarginine. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20080201
[Differentiation of 2 endothelial progenitor cells in vitro and inhibitory effect of asymmetric dimethylarginine on its proliferation]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080201
Asymmetrical dimethylarginine level in atrial fibrillation. Acta cardiologica 20080201
Catechin combined with vitamins C and E ameliorates insulin resistance (IR) and atherosclerotic changes in aged rats with chronic renal failure (CRF). Archives of gerontology and geriatrics 20080101
Aqueous humor levels of asymmetric dimethylarginine (ADMA) are positively associated with monocyte chemoattractant protein-1 (MCP-1) in patients with uveitis. The British journal of ophthalmology 20080101
Reduced asymmetric dimethylarginine (ADMA) levels mediate in the protection from metabolic syndrome by smoking. Atherosclerosis 20080101
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. British journal of clinical pharmacology 20080101
Oxidative stress and asymmetric dimethylarginine is independently associated with carotid intima media thickness in peritoneal dialysis patients. American journal of nephrology 20080101
Nitric oxide deficiency in chronic kidney disease. American journal of physiology. Renal physiology 20080101
Asymmetrical dimethylarginine, inflammatory and metabolic parameters in women with polycystic ovary syndrome before and after metformin treatment. The Journal of clinical endocrinology and metabolism 20080101
Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation. Stroke 20080101
The relationship between plasma asymmetrical dimethyl-L-arginine and inflammation and adhesion molecule levels in subjects with normal, impaired, and diabetic glucose tolerance. Metabolism: clinical and experimental 20080101
Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants. American journal of obstetrics and gynecology 20080101
ADMA correlates with portal pressure in patients with compensated cirrhosis by Vizzutti et al. Eur J Clin Invest 2007; 37: 509-15. European journal of clinical investigation 20080101
Effects of normalization of plasma testosterone levels in hypogonadal men on plasma levels and urinary excretion of asymmetric dimethylarginine (ADMA). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080101
Polycystic ovarian syndrome, biomarkers, and metformin: research, risk, and reality. The Journal of clinical endocrinology and metabolism 20080101
The role of asymmetric dimethylarginine (ADMA) and leptin in hypertensive patients. The Journal of international medical research 20080101
Response of asymmetric dimethylarginine to hemodialysis-associated hypotension in end-stage renal disease patients. Nephron. Clinical practice 20080101
Increased plasma asymmetric dimethylarginine (ADMA) levels in retinal venous occlusive disease. Clinical chemistry and laboratory medicine 20080101
Effect of simvastatin on plasma asymmetric dimethylarginine concentration in patients with chronic kidney disease. Journal of nephrology 20080101
Asymmetric dimethylarginine induces TNF-alpha production via ROS/NF-kappaB dependent pathway in human monocytic cells and the inhibitory effect of reinioside C. Vascular pharmacology 20080101
Impact of catheter arteriography on the serum level of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase. Cardiovascular and interventional radiology 20080101
The effects of renal replacement therapy on plasma, asymmetric dimethylarginine, nitric oxide and C-reactive protein levels. Clinical and investigative medicine. Medecine clinique et experimentale 20080101
Oxidative stress and asymmetric dimethylarginine are associated with cardiovascular complications in hemodialysis patients: improvements by L-arginine intake. Kidney & blood pressure research 20080101
Effects of oral L-arginine supplementation on blood pressure and asymmetric dimethylarginine in stress-induced preeclamptic rats. Cell biochemistry and function 20080101
Asymmetric dimethylarginine--mechanisms and targets for therapeutic management. Folia medica 20080101
Evaluation of the relationship between flow-mediated vasodilation and some atherogenic risk markers in severe hypercholesterolemia. Folia medica 20080101
The relationship among asymmetric dimethylarginine (ADMA) levels, residual renal function, and left ventricular hypertrophy in continuous ambulatory peritoneal dialysis patients. Renal failure 20080101
Asymmetrical dimethylarginine is increased in plasma and decreased in cerebrospinal fluid of patients with Alzheimer's disease. Dementia and geriatric cognitive disorders 20080101
Molecular mechanisms of endothelial dysfunction: from nitric oxide synthesis to ADMA inhibition. American journal of therapeutics 20080101
[Asymmetric dimethylarginine (ADMA): A cardiovascular risk factor]. Wiener klinische Wochenschrift 20080101
Reduction of plasma asymmetric dimethylarginine in obese patients with chronic kidney disease after three years of a low-protein diet supplemented with keto-amino acids: a randomized controlled trial. Wiener klinische Wochenschrift 20080101
Cardiac biomarkers and chronic renal diseases. Bratislavske lekarske listy 20080101
[Novelties in the field of progression factors in chronic kidney disease]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20080101
Relation between asymmetric dimethylarginine (ADMA) and hearing loss in patients with renal impairment. Renal failure 20080101
Plasma levels of asymmetric dimethylarginine in cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy. Cerebrovascular diseases (Basel, Switzerland) 20080101
Role of asymmetric dimethylarginine (ADMA) in diabetic vascular complications. Current pharmaceutical design 20080101
Role of some biomarkers of atherogenic risk in the screening for molecular defects in the low density lipoprotein receptor in severe hypercholesterolemia. Folia medica 20080101
L-Arginine, ADMA, SDMA, creatinine, MDRD formula: detour to renal function testing. Journal of nephrology 20080101
Waist circumference is associated with asymmetric dimethylarginine levels in patients with metabolic syndrome. Acta clinica Belgica 20080101
Dysfunction of endothelial NO system originated from homocysteine-induced aberrant methylation pattern in promoter region of DDAH2 gene. Chinese medical journal 20071205
Asymmetric dimethylarginine is increased in chronic thromboembolic pulmonary hypertension. American journal of respiratory and critical care medicine 20071201
Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems. American journal of physiology. Heart and circulatory physiology 20071201
Nebivolol reduces asymmetric dimethylarginine in endothelial cells by increasing dimethylarginine dimethylaminohydrolase 2 (DDAH2) expression and activity. Pharmacological research 20071201
Assessment of protein-incorporated arginine methylation in biological specimens by CZE UV-detection. Electrophoresis 20071201
Effect of telmisartan on forearm postischemic hyperemia and serum asymmetric dimethylarginine levels. American journal of hypertension 20071201
Contrast-induced nephropathy and mortality: possible crucial role of asymmetric dimethylarginine. Journal of cardiovascular medicine (Hagerstown, Md.) 20071201
Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia. The Journal of biological chemistry 20071130
Plasma concentrations of asymmetric dimethylarginine (ADMA) in metabolic syndrome. International journal of cardiology 20071115
Direct analysis of un-derivatized asymmetric dimethylarginine (ADMA) and L-arginine from plasma using mixed-mode ion-exchange liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071115
Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy. Circulation 20071113
Role of DDAH-1 in lipid peroxidation product-mediated inhibition of endothelial NO generation. American journal of physiology. Cell physiology 20071101
Plasma asymmetric dimethylarginine and L-arginine levels in patients with cardiac syndrome X. Coronary artery disease 20071101
Asymmetric dimethylarginine plasma concentrations and L-arginine/asymmetric dimethylarginine ratio in patients with slow coronary flow. Coronary artery disease 20071101
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. Journal of neurosurgery 20071101
Rosiglitazone improves endothelial function and inflammation but not asymmetric dimethylarginine or oxidative stress in patients with type 2 diabetes mellitus. Vascular medicine (London, England) 20071101
GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015
Insulin and adiponectin inhibit the TNFalpha-induced ADMA accumulation in human endothelial cells: the role of DDAH. Atherosclerosis 20071001
Determination of dimethylarginine dimethylaminohydrolase activity in the kidney. Kidney international 20071001
Asymmetric dimethylarginine is associated with parameters of glucose metabolism in Caucasian but not in African women from South Africa. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20071001
Temporal effects of low-dose ACE inhibition on endothelial function in Type 1 diabetic patients. Journal of endocrinological investigation 20071001
Reduction of NO- and EDHF-mediated vasodilatation in hypertension: role of asymmetric dimethylarginine. Clinical and experimental hypertension (New York, N.Y. : 1993) 20071001
Brachial artery flow-mediated dilation and asymmetrical dimethylarginine in the cardiovascular risk in young Finns study. Circulation 20070918
Oxidative stress in cardiovascular disease: successful translation from bench to bedside? Circulation 20070918
Isoform-specific regulation by N(G),N(G)-dimethylarginine dimethylaminohydrolase of rat serum asymmetric dimethylarginine and vascular endothelium-derived relaxing factor/NO. Circulation research 20070914
Tilarginine in patients with acute myocardial infarction and cardiogenic shock. JAMA 20070905
Pressure-related increase of asymmetric dimethylarginine caused by hyperbaric oxygen in the rat brain: a possible neuroprotective mechanism. Neurochemical research 20070901
Asymmetric dimethylarginine enhances cardiovascular risk prediction in patients with chronic heart failure. Arteriosclerosis, thrombosis, and vascular biology 20070901
Asymmetric dimethylarginine (ADMA)--a modulator of nociception in opiate tolerance and addiction? Nitric oxide : biology and chemistry 20070901
Arginase: a critical regulator of nitric oxide synthesis and vascular function. Clinical and experimental pharmacology & physiology 20070901
Presence of asymmetric dimethylarginine gradients across high-grade lesions in patients with coronary artery disease. Coronary artery disease 20070901
Dimethylarginine dimethylaminohydrolase: a new therapeutic target for the modulation of nitric oxide and angiogenesis. Current opinion in investigational drugs (London, England : 2000) 20070901
Soluble RAGE in type 2 diabetes: association with oxidative stress. Free radical biology & medicine 20070815
Asymmetric dimethylarginine (ADMA) in vascular, renal and hepatic disease and the regulatory role of L-arginine on its metabolism. Molecular genetics and metabolism 20070801
Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery. Critical care medicine 20070801
Reduction of asymmetric dimethylarginine involved in the cardioprotective effect of losartan in spontaneously hypertensive rats. Canadian journal of physiology and pharmacology 20070801
Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2. Circulation research 20070720
Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury. Cardiovascular research 20070715
Chronic kidney disease: effects on the cardiovascular system. Circulation 20070703
Flow- and acetylcholine-induced dilatation in small arteries from rats with renovascular hypertension--effect of tempol treatment. European journal of pharmacology 20070702
Effects of combined supplementation with B vitamins and antioxidants on plasma levels of asymmetric dimethylarginine (ADMA) in subjects with elevated risk for cardiovascular disease. Atherosclerosis 20070701
Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes. Diabetes care 20070701
Serum leptin, oxidized low density lipoprotein and plasma asymmetric dimethylarginine levels and their relationship with dyslipidaemia in adolescent girls with polycystic ovary syndrome. Clinical endocrinology 20070701
Asymmetric dimethylarginine and hypertension in cerebral small vessel disease. Stroke 20070701
Asymmetric dimethylarginine is a marker of poor prognosis and coronary calcium in systemic lupus erythematosus. The Journal of rheumatology 20070701
Hyperbaric oxygen therapy mediates increased nitric oxide production associated with wound healing: a preliminary study. Advances in skin & wound care 20070701
Effects of atorvastatin therapy on hypercholesterolemic rabbits with respect to oxidative stress, nitric oxide pathway and homocysteine. Life sciences 20070620
Asymmetric dimethylarginine determines the improvement of endothelium-dependent vasodilation by simvastatin: Effect of combination with oral L-arginine. Journal of the American College of Cardiology 20070612
Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs. Research in veterinary science 20070601
High-throughput CZE-UV determination of arginine and dimethylated arginines in human plasma. Electrophoresis 20070601
Increased asymmetric dimethylarginine concentrations in stimulated peripheral blood mononuclear cells. Scandinavian journal of immunology 20070601
ADMA correlates with portal pressure in patients with compensated cirrhosis. European journal of clinical investigation 20070601
Asymmetric dimethylarginine (ADMA) is a novel emerging risk factor for cardiovascular disease and the development of renal injury in chronic kidney disease. Clinical and experimental nephrology 20070601
[Effect of asymmetric dimethylarginine on the activation of hepatic stellate cells and its mechanism]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070601
HPLC analysis of ADMA and other methylated L-arginine analogs in biological fluids. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515
Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515
An overview of plasma concentrations of asymmetric dimethylarginine (ADMA) in health and disease and in clinical studies: methodological considerations. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515
High-throughput liquid chromatographic-tandem mass spectrometric determination of arginine and dimethylated arginine derivatives in human and mouse plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515
A stable-isotope based technique for the determination of dimethylarginine dimethylaminohydrolase (DDAH) activity in mouse tissue. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515
Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells. American journal of respiratory cell and molecular biology 20070501
Taurine protects against low-density lipoprotein-induced endothelial dysfunction by the DDAH/ADMA pathway. Vascular pharmacology 20070501
Dimethylarginine dimethylaminohydrolase prevents progression of renal dysfunction by inhibiting loss of peritubular capillaries and tubulointerstitial fibrosis in a rat model of chronic kidney disease. Journal of the American Society of Nephrology : JASN 20070501
A new perspective for the treatment of renal diseases? Journal of the American Society of Nephrology : JASN 20070501
Biological variation of asymmetric dimethylarginine and related arginine metabolites and analytical performance goals for their measurement in human plasma. European journal of clinical investigation 20070501
Regulation by DDAH/ADMA pathway of lipopolysaccharide-induced tissue factor expression in endothelial cells. Thrombosis and haemostasis 20070501
Plasma adhesion and inflammation markers: asymmetrical dimethyl-L-arginine and secretory phospholipase A2 concentrations before and after laparoscopic gastric banding in morbidly obese patients. Obesity surgery 20070501
Asymmetric dimethylarginine and reduced nitric oxide bioavailability in young Black African men. Hypertension (Dallas, Tex. : 1979) 20070401
Asymmetric dimethylarginine, smoking, and risk of coronary heart disease in apparently healthy men: prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in der Region Augsburg study and experimental data. Clinical chemistry 20070401
ADMA is independently related to flow-mediated vasodilation in subjects at low cardiovascular risk. European journal of clinical investigation 20070401
Beneficial metabolic effects of nateglinide versus acarbose in patients with newly-diagnosed type 2 diabetes. Acta pharmacologica Sinica 20070401
Asymmetric dimethylarginine (ADMA) in the aqueous humor of diabetic patients. Endocrine journal 20070401
Effects of a supplement containing isoflavones and Actaea racemosa L. on asymmetric dimethylarginine, lipids, and C-reactive protein in menopausal women. Fertility and sterility 20070401
Asymmetric dimethyl-arginine and coronary artery calcification in young adults entering middle age: the CARDIA Study. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20070401
The past, presence and future of ADMA in nephrology. Nephrologie & therapeutique 20070401
Unchanged asymmetric dimethylarginine levels in non-diabetic, premenopausal obese women who have common risk factors for cardiovascular disease. Endocrine 20070401
The ADMA/DDAH pathway is a critical regulator of endothelial cell motility. Journal of cell science 20070315
Dimethylarginine dimethylaminohydrolase promotes endothelial repair after vascular injury. Journal of the American College of Cardiology 20070313
Plasma levels of asymmetric dimethylarginine (ADMA) are related to intima-media thickness of the carotid artery: an epidemiological study. Atherosclerosis 20070301
Asymmetrical dimethylarginine (ADMA) and coronary endothelial function in patients with coronary artery disease and mild hypercholesterolemia. Atherosclerosis 20070301
Asymmetric dimethylarginine reduced erythrocyte deformability in streptozotocin-induced diabetic rats. Microvascular research 20070301
Asymmetric dimethyl-arginine (ADMA) response to inflammation in acute infections. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070301
Asymmetrical dimethylarginine inhibits shear stress-induced nitric oxide release and dilation and elicits superoxide-mediated increase in arteriolar tone. Hypertension (Dallas, Tex. : 1979) 20070301
Dimethylarginines at the crossroad of insulin resistance and atherosclerosis. Metabolism: clinical and experimental 20070301
Arterial wave reflections and determinants of endothelial function a hypothesis based on peripheral mode of action. American journal of hypertension 20070301
Elevated plasma asymmetric dimethyl-L-arginine levels are linked to endothelial progenitor cell depletion and carotid atherosclerosis in rheumatoid arthritis. Arthritis and rheumatism 20070301
Oral administration of both tetrahydrobiopterin and L-arginine prevents endothelial dysfunction in rats with chronic renal failure. Journal of cardiovascular pharmacology 20070301
Asymmetric dimethylarginine levels in thyroid diseases. Journal of endocrinological investigation 20070301
Asymmetric dimethylarginine (ADMA) induces vascular endothelium impairment and aggravates post-ischemic ventricular dysfunction in rats. European journal of pharmacology 20070227
Asymmetric dimethylarginine is not elevated in exfoliation syndrome but symmetric dimethylarginine is related to exfoliative glaucoma. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070201
Asymmetrical dimethylarginine independently predicts total and cardiovascular mortality in individuals with angiographic coronary artery disease (the Ludwigshafen Risk and Cardiovascular Health study). Clinical chemistry 20070201
Asymmetric dimethylarginine in cerebral small vessel disease. Stroke 20070201
Increased plasma levels of asymmetric dimethylarginine in patients with carotid stenosis: no evidence for the role of the common FABP2 A54T gene polymorphism. Acta neurologica Scandinavica 20070201
Should we measure asymmetric dimethylarginine in patients with coronary artery disease? Clinical chemistry 20070201
[Coronary allograft vasculopathy: pathophysiological interaction between the immune system, infections and metabolic syndrome]. Giornale italiano di cardiologia (2006) 20070201
The inhibitory effect of simvastatin on the ADMA-induced inflammatory reaction is mediated by MAPK pathways in endothelial cells. Biochemistry and cell biology = Biochimie et biologie cellulaire 20070201
Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function. The Journal of biological chemistry 20070112
Dimethylarginine dimethylaminohydrolase inhibition and asymmetric dimethylarginine accumulation contribute to endothelial dysfunction in rats exposed to glycosylated protein: effects of aminoguanidine. Atherosclerosis 20070101
Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA. American journal of physiology. Lung cellular and molecular physiology 20070101
Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression. Journal of applied physiology (Bethesda, Md. : 1985) 20070101
The lung in the balance: arginine, methylated arginines, and nitric oxide. American journal of physiology. Lung cellular and molecular physiology 20070101
Elevated plasma asymmetric dimethyl-L-arginine in a patient with Gordon syndrome. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070101
Asymmetric dimethylarginine (ADMA) and hyperhomocysteinemia in patients with acute myocardial infarction. Clinical biochemistry 20070101
Pioglitazone improves endothelial function in non-diabetic patients with coronary artery disease. Cardiology 20070101
Nontraditional atherosclerotic risk factors and extent of coronary atherosclerosis in patients with combined impaired fasting glucose and impaired glucose tolerance. Metabolism: clinical and experimental 20070101
Asymmetric dimethylarginine, cortisol/cortisone ratio, and C-peptide: markers for diabetes and cardiovascular risk? American heart journal 20070101
Increasing dimethylarginine levels are associated with adverse clinical outcome in severe alcoholic hepatitis. Hepatology (Baltimore, Md.) 20070101
Effects of alpha-lipoic acid on the plasma levels of asymmetric dimethylarginine in diabetic end-stage renal disease patients on hemodialysis: a pilot study. American journal of nephrology 20070101
Serum asymmetric dimethylarginine negatively correlates with intima-media thickness in early-onset atherosclerosis. Cerebrovascular diseases (Basel, Switzerland) 20070101
Role of asymmetric dimethylarginine in inflammatory reactions by angiotensin II. Journal of vascular research 20070101
C-reactive protein and asymmetric dimethylarginine: markers or mediators in cardiovascular disorders? Current pharmaceutical design 20070101
Improvement in central arterial pressure waveform during hemodialysis is related to a reduction in asymmetric dimethylarginine (ADMA) levels. Nephron. Clinical practice 20070101
Plasma asymmetric dimethylarginine concentration during the perinatal period. Neonatology 20070101
Plasma dimethylarginine levels in chronic hemodialysis patients are independent of the type of dialyzer applied. Blood purification 20070101
Measurement of arginine derivatives in pediatric patients with chronic kidney disease using high-performance liquid chromatography-tandem mass spectrometry. Clinical chemistry and laboratory medicine 20070101
Lowering asymmetric dimethylarginine--a new mechanism mediating the renoprotective effects of renin-angiotensin system inhibitors in proteinuric patients? Blood purification 20070101
Improving proteinuria, endothelial functions and asymmetric dimethylarginine levels in chronic kidney disease: ramipril versus valsartan. Blood purification 20070101
Impaired vascular nitric oxide bioactivity in women with previous gestational diabetes. Wiener klinische Wochenschrift 20070101
Changes of asymmetric dimethylarginine, nitric oxide, tetrahydrobiopterin, and oxidative stress in patients with acute myocardial infarction by medical treatments. Clinical hemorheology and microcirculation 20070101
Possible involvement of enhanced arginase activity due to up-regulated arginases and decreased hydroxyarginine in accelerating intimal hyperplasia with hyperglycemia. Vascular pharmacology 20070101
Health-associated reference values for arginine, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) measured with high-performance liquid chromatography. Scandinavian journal of clinical and laboratory investigation 20070101
Down-regulation of endogenous nitric oxide synthase inhibitors on endothelial SK3 expression. Vascular pharmacology 20070101
From Zanius to ADMA: ADMA - a new ''adipocytokine'' and its potential role in metabolic syndrome. Journal of nephrology 20070101
The enzymatic machinery for ADMA synthesis and degradation is fully expressed in human adipocytes. Journal of nephrology 20070101
Homocysteine and asymmetric dimethylarginine (ADMA): biochemically linked but differently related to vascular disease in chronic kidney disease. Clinical chemistry and laboratory medicine 20070101
The endothelium as a target in renal diseases. Journal of nephrology 20070101
Aqueous humour levels of asymmetric dimethylarginine (ADMA) are correlated with pigment epithelium-derived factor (PEDF) in patients with uveitis. The Journal of international medical research 20070101
Plasma biomarkers of endothelial dysfunction in patients with hypertrophic cardiomyopathy. Pharmacological reports : PR 20070101
[Does tobacco smoke influence the concentration of asymmetric dimethylarginine (ADMA) in healthy males plasma?]. Przeglad lekarski 20070101
Farnesoid X receptor agonist reduces serum asymmetric dimethylarginine levels through hepatic dimethylarginine dimethylaminohydrolase-1 gene regulation. The Journal of biological chemistry 20061229
Protein arginine methylation: Cellular functions and methods of analysis. Biochimica et biophysica acta 20061201
Asymmetric dimethylarginine and cerebrovascular disorders in humans. Stroke 20061201
Effects of amlodipine and valsartan on oxidative stress and plasma methylarginines in end-stage renal disease patients on hemodialysis. Kidney international 20061201
Changes of plasma asymmetric dimethylarginine levels after coronary artery bypass grafting. Scandinavian cardiovascular journal : SCJ 20061201
Asymmetric dimethylarginine in end-stage renal disease patients: a biomarker modifiable by calcium blockade and angiotensin II antagonism? Kidney international 20061201
Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine in citrullinemia. Metabolism: clinical and experimental 20061201
[Effect of puerarin on ADMA-DDAH system in human umbilical vein endothelial cells cultured with oxidized free radical]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20061201
Determination of NG,NG-dimethyl-L-arginine in rat plasma and dimethylarginine dimethylaminohydrolase activity in rat kidney using a monolithic silica column. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061107
Asymmetric dimethylarginine is associated with macrovascular disease and total homocysteine in patients with type 2 diabetes. Atherosclerosis 20061101
Asymmetric dimethylarginine predicts major adverse cardiovascular events in patients with advanced peripheral artery disease. Arteriosclerosis, thrombosis, and vascular biology 20061101
Plasma asymmetric dimethylarginine level and extent of lesion at coronary angiography. Coronary artery disease 20061101
Association of homocysteine and asymmetric dimethylarginine with atherosclerosis and cardiovascular events in maintenance hemodialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 20061101
Involvement of DDAH/ADMA/NOS pathway in nicotine-induced endothelial dysfunction. Biochemical and biophysical research communications 20061020
Cigarettes and ADMA: the smoke hasn't cleared yet. Hypertension (Dallas, Tex. : 1979) 20061001
Salt loading on plasma asymmetrical dimethylarginine and the protective role of potassium supplement in normotensive salt-sensitive asians. Hypertension (Dallas, Tex. : 1979) 20061001
Medium-term methionine supplementation increases plasma homocysteine but not ADMA and improves blood pressure control in rats fed a diet rich in protein and adequate in folate and choline. European journal of nutrition 20061001
Level of asymmetric dimethylarginine and carotid atherosclerosis in patients with chronic kidney disease. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20061001
[Effect of asymmetric dimethylarginine on platelet-aggregation and losartan intervention in spontaneous hypertensive rat models]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20061001
Vaso-occlusion in Schimke-immuno-osseous dysplasia: is the NO pathway involved? Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20061001
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH. Neurological research 20061001
[Dimethylarginine dimethylaminohydrolase and endothelium dysfunction]. Sheng li ke xue jin zhan [Progress in physiology] 20061001
Plasma asymmetric dimethylarginine (ADMA), nitrate and the indices of low-density lipoprotein oxidation. Clinica chimica acta; international journal of clinical chemistry 20060901
L-arginine chlorination results in the formation of a nonselective nitric-oxide synthase inhibitor. The Journal of pharmacology and experimental therapeutics 20060901
Asymmetric dimethylarginine is an independent risk factor for coronary heart disease: results from the multicenter Coronary Artery Risk Determination investigating the Influence of ADMA Concentration (CARDIAC) study. American heart journal 20060901
Gene polymorphism and requirement for vasopressor infusion after cardiac surgery. The Annals of thoracic surgery 20060901
Effect of iloprost on plasma asymmetric dimethylarginine and plasma and platelet serotonin in patients with peripheral arterial occlusive disease. Prostaglandins & other lipid mediators 20060901
Letter by Kielstein et al regarding article, 'Renal function as a predictor of outcome in a broad spectrum of patients with heart failure'. Circulation 20060808
Adverse effects of cigarette smoke on NO bioavailability: role of arginine metabolism and oxidative stress. Hypertension (Dallas, Tex. : 1979) 20060801
Molecular mechanism for elevation of asymmetric dimethylarginine and its role for hypertension in chronic kidney disease. Journal of the American Society of Nephrology : JASN 20060801
ADMA increases arterial stiffness and decreases cerebral blood flow in humans. Stroke 20060801
ADMA, proteinuria, and insulin resistance in non-diabetic stage I chronic kidney disease. Kidney international 20060801
Cross-talk between the kidney and the cardiovascular system. Journal of the American Society of Nephrology : JASN 20060801
Probucol decreases asymmetrical dimethylarginine level by alternation of protein arginine methyltransferase I and dimethylarginine dimethylaminohydrolase activity. Cardiovascular drugs and therapy 20060801
Endogenous inhibitors of nitric oxide and preeclampsia: a review. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20060801
Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging. Biochemical and biophysical research communications 20060707
Umbilical vein plasma concentrations of asymmetrical dimethylarginine are increased in male but not female neonates delivered preterm: a pilot study. Early human development 20060701
L-arginine: a new opportunity in the management of clinical derangements in dialysis patients. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20060701
[Nitric oxide]. Nihon rinsho. Japanese journal of clinical medicine 20060701
Analysis of asymmetric dimethylarginine in plasma by HPLC using a monolithic column. Analytical biochemistry 20060615
Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine. Rheumatology (Oxford, England) 20060601
Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide. Climacteric : the journal of the International Menopause Society 20060601
Intensive treatment of risk factors in patients with type-2 diabetes mellitus is associated with improvement of endothelial function coupled with a reduction in the levels of plasma asymmetric dimethylarginine and endogenous inhibitor of nitric oxide synthase. European heart journal 20060501
Urotensin II and biomarkers of endothelial activation and atherosclerosis in end-stage renal disease. American journal of hypertension 20060501
No effect of B vitamins on ADMA levels in patients at increased cardiovascular risk. Clinical endocrinology 20060501
Asymmetric arginine dimethylation of heterogeneous nuclear ribonucleoprotein K by protein-arginine methyltransferase 1 inhibits its interaction with c-Src. The Journal of biological chemistry 20060421
Endothelial dysfunction induced by postprandial lipemia is neutralized by addition of proteins to the fatty meal. Atherosclerosis 20060401
Asymmetric dimethyl arginine levels correlate with cardiovascular risk factors in patients with erectile dysfunction. Atherosclerosis 20060401
Asymmetric dimethylarginine (ADMA) as a risk marker for stroke and TIA in a Swedish population. Atherosclerosis 20060401
Coronary endothelial dysfunction is associated with erectile dysfunction and elevated asymmetric dimethylarginine in patients with early atherosclerosis. European heart journal 20060401
Asymmetric dimethylarginine induces apoptosis via p38 MAPK/caspase-3-dependent signaling pathway in endothelial cells. Journal of molecular and cellular cardiology 20060401
Asymmetric dimethylarginine (ADMA): a cardiovascular and renal risk factor on the move. Journal of hypertension 20060401
Arginine, arginine analogs and nitric oxide production in chronic kidney disease. Nature clinical practice. Nephrology 20060401
L-NAME- and ADMA-induced sympathetic neural activation in conscious rats. American journal of physiology. Regulatory, integrative and comparative physiology 20060301
Lysophosphatidylcholine-induced elevation of asymmetric dimethylarginine level by the NADPH oxidase pathway in endothelial cells. Vascular pharmacology 20060301
Fast and efficient determination of arginine, symmetric dimethylarginine, and asymmetric dimethylarginine in biological fluids by hydrophilic-interaction liquid chromatography-electrospray tandem mass spectrometry. Clinical chemistry 20060301
Detection of dimethylarginines in protein hydrolysates by matrix-assisted laser desorption/ionization mass spectrometry. Analytical biochemistry 20060301
Effect of fenofibrate on the level of asymmetric dimethylarginine in individuals with hypertriglyceridemia. European journal of clinical pharmacology 20060301
Effect of vasoconstrictor coupling factor 6 on gene expression profile in human vascular endothelial cells: enhanced release of asymmetric dimethylarginine. Journal of hypertension 20060301
[Asymmetric dimethylarginine--a novel cardiovascular risk factor]. Vnitrni lekarstvi 20060301
Comparison of HPLC method and commercial ELISA assay for asymmetric dimethylarginine (ADMA) determination in human serum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202
Relations between plasma asymmetric dimethylarginine (ADMA) and risk factors for coronary disease. Atherosclerosis 20060201
Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover. Diabetologia 20060201
Treatment with niacin lowers ADMA. Atherosclerosis 20060201
High glucose-mediated imbalance of nitric oxide synthase and dimethylarginine dimethylaminohydrolase expression in endothelial cells. Current neurovascular research 20060201
[Nephrosclerosis: Pathogenesis, pathophysiology, and therapy]. Nihon rinsho. Japanese journal of clinical medicine 20060201
[Protective effect of losartan on injury induced by ox-LDL in endothelial cells and the relationship with asymmetric dimethylarginine]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20060201
Asymmetric dimethylarginine in homocystinuria due to cystathionine beta-synthase deficiency: relevance of renal function. Journal of inherited metabolic disease 20060201
Plasma markers of NO synthase activity in women after ovarian hyperstimulation: influence of estradiol on ADMA. Vascular medicine (London, England) 20060201
Epigallocatechin gallate preserves endothelial function by reducing the endogenous nitric oxide synthase inhibitor level. Canadian journal of physiology and pharmacology 20060201
The determinants of endothelial dysfunction in CKD: oxidative stress and asymmetric dimethylarginine. American journal of kidney diseases : the official journal of the National Kidney Foundation 20060101
Accumulation of symmetric dimethylarginine in hepatorenal syndrome. Experimental biology and medicine (Maywood, N.J.) 20060101
Estrogen replacement effectively improves the accelerated intimal hyperplasia following balloon injury of carotid artery in the ovariectomized rats. Journal of cardiovascular pharmacology 20060101
[The best of epidemiology and cardiovascular prevention in 2005]. Archives des maladies du coeur et des vaisseaux 20060101
Management of intradialytic hypertension: the ongoing challenge. Seminars in dialysis 20060101
No benefit of hemodiafiltration over hemodialysis in lowering elevated levels of asymmetric dimethylarginine in ESRD patients. Blood purification 20060101
Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a prospective observational study. Critical care (London, England) 20060101
Live and let die: asymmetric dimethylarginine and septic shock. Critical care (London, England) 20060101
Asymmetric dimethylarginine and nitric oxide levels as signs of endothelial dysfunction in Behcet's disease. Annals of clinical and laboratory science 20060101
[The influence of tobacco smoke on plasma atherogenic compounds levels in active smokers (preliminary report)]. Przeglad lekarski 20060101
Asymmetric dimethylarginine (ADMA) a novel cardiovascular risk factor--evidence from epidemiological and prospective clinical trials. Pharmacological reports : PR 20060101
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation. Arteriosclerosis, thrombosis, and vascular biology 20051201
Long-term use of vitamin E-coated polysulfone membrane reduces oxidative stress markers in haemodialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051201
Serum asymmetric dimethylarginine as a marker of coronary microcirculation in patients with non-insulin dependent diabetes mellitus: correlation with coronary flow reserve. Heart (British Cardiac Society) 20051201
Dissociation between the short-term effects of nocturnal hemodialysis on endothelium dependent vasodilation and plasma ADMA. Arteriosclerosis, thrombosis, and vascular biology 20051201
A role for asymmetric dimethylarginine in the pathophysiology of portal hypertension in rats with biliary cirrhosis. Hepatology (Baltimore, Md.) 20051201
A gas, an amino acid, and an imposter: the story of nitric oxide, L-arginine, and ADMA in portal hypertension. Hepatology (Baltimore, Md.) 20051201
Elevated serum interleukin-18 levels might reflect the high risk of hospitalization in patients on peritoneal dialysis. Nephrology (Carlton, Vic.) 20051201
Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage renal disease. American journal of hypertension 20051201
Free fatty acids do not acutely increase asymmetrical dimethylarginine concentrations. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051201
Endurance training reduces circulating asymmetric dimethylarginine and myeloperoxidase levels in persons at risk of coronary events. Thrombosis and haemostasis 20051201
Biomarkers in chronic kidney disease: utility and issues towards better understanding. Current opinion in nephrology and hypertension 20051101
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Determination of asymmetric dimethylarginine: liquid chromatography-mass spectrometry or ELISA? Clinical chemistry 20051101
Reduced nitric oxide concentration in the renal cortex of streptozotocin-induced diabetic rats: effects on renal oxygenation and microcirculation. Diabetes 20051101
Endothelial function and its assessment. Expert opinion on investigational drugs 20051101
Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine. Journal of the American College of Cardiology 20051101
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The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease. Journal of hypertension 20051001
Determination of methylated arginines by column-switching high-performance liquid chromatography-fluorescence detection. The Analyst 20051001
Determination of a reference value for N(G), N(G)-dimethyl-L-arginine in 500 subjects. European journal of clinical investigation 20051001
Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA. PLoS medicine 20051001
In vitro and in vivo effects of probucol on hydrolysis of asymmetric dimethyl L-arginine and vasospasm in primates. Journal of neurosurgery 20051001
Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease. Circulation 20050913
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Raised plasma levels of asymmetric dimethylarginine are associated with cardiovascular events, disease activity, and organ damage in patients with systemic lupus erythematosus. Annals of the rheumatic diseases 20050901
An association between plasma asymmetric dimethylarginine and membrane fluidity of erythrocytes in hypertensive and normotensive men: an electron paramagnetic resonance investigation. American journal of hypertension 20050901
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Increased circulating concentrations of asymmetric dimethylarginine (ADMA) in white coat hypertension. Journal of human hypertension 20050801
Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study. Journal of the American Society of Nephrology : JASN 20050801
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The effects of thyroxine replacement on the levels of serum asymmetric dimethylarginine (ADMA) and other biochemical cardiovascular risk markers in patients with subclinical hypothyroidism. Clinical endocrinology 20050801
A selective estrogen receptor modulator, tamoxifen, and membrane fluidity of erythrocytes in normotensive and hypertensive postmenopausal women: an electron paramagnetic resonance investigation. American journal of hypertension 20050801
Asymmetric dimethylarginine: a cardiovascular risk factor and a uremic toxin coming of age? American journal of kidney diseases : the official journal of the National Kidney Foundation 20050801
Homocysteine-induced vascular dysregulation is mediated by the NMDA receptor. Vascular medicine (London, England) 20050801
Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase. Journal of medicinal chemistry 20050714
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701
Asymmetrical dimethylarginine in idiopathic pulmonary arterial hypertension. Arteriosclerosis, thrombosis, and vascular biology 20050701
Liquid chromatography-tandem mass spectrometry method for the analysis of asymmetric dimethylarginine in human plasma. Clinical chemistry 20050701
ADMA: an emerging cardiovascular risk factor. Vascular medicine (London, England) 20050701
Endogenous production of nitric oxide synthase inhibitors. Vascular medicine (London, England) 20050701
ADMA: its role in vascular disease. Vascular medicine (London, England) 20050701
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ADMA and hyperhomocysteinemia. Vascular medicine (London, England) 20050701
Insulin resistance: potential role of the endogenous nitric oxide synthase inhibitor ADMA. Vascular medicine (London, England) 20050701
DDAH gene and cardiovascular risk. Vascular medicine (London, England) 20050701
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Spotlight on endothelial progenitor cell inhibitors: short review. Vascular medicine (London, England) 20050701
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Quantification of ADMA: analytical approaches. Vascular medicine (London, England) 20050701
ADMA and oxidative stress may relate to the progression of renal disease: rationale and design of the VIVALDI study. Vascular medicine (London, England) 20050701
Proceedings of the 2nd International Symposium on ADMA -- An Emerging Cardiovascular Risk Factor, November 6, 2004, New Orleans, Louisiana, USA. Vascular medicine (London, England) 20050701
Asymmetrical dimethylarginine plasma concentrations are related to basal nitric oxide release but not endothelium-dependent vasodilation of resistance arteries in peritoneal dialysis patients. Journal of the American Society of Nephrology : JASN 20050601
Prognostic value of combined use of biomarkers of inflammation, endothelial dysfunction, and myocardiopathy in patients with ESRD. Kidney international 20050601
Effect of diabetic duration on serum concentrations of endogenous inhibitor of nitric oxide synthase in patients and rats with diabetes. Life sciences 20050527
Plasma levels of asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, are elevated in sickle cell disease. Annals of hematology 20050501
Endothelial cell dysfunction: the syndrome in making. Kidney international 20050501
Erythropoietin increases asymmetric dimethylarginine in endothelial cells: role of dimethylarginine dimethylaminohydrolase. Journal of the American Society of Nephrology : JASN 20050401
Acute hyperhomocysteinemia decreases NO bioavailability in healthy adults. Atherosclerosis 20050401
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Circulation 20050322
A new method for the liquid chromatography analysis of methylated arginines in biological fluids and tissues by o-phthaldialdehyde postcolumn derivatization. Analytical biochemistry 20050315
Plasma asymmetric dimethylarginine concentrations in newly diagnosed patients with acute myocardial infarction or unstable angina pectoris during two weeks of medical treatment. The American journal of cardiology 20050315
Home-based exercise training modulates pro-oxidant substrates in patients with chronic heart failure. European journal of heart failure 20050302
Elevated plasma concentration of asymmetric dimethylarginine that is reduced by single dose testosterone administration in idiopathic hypogonadotropic hypogonadism patients. The Journal of clinical endocrinology and metabolism 20050301
Circulating ADMA concentrations are elevated in hypopituitary adults with and without growth hormone deficiency. European journal of clinical investigation 20050301
Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality? Critical care medicine 20050301
Hyperglycemia, asymmetric dimethylarginine, and patient survival: Dysregulation of complex networks and the metabolic basis of disease. Critical care medicine 20050301
L-Arginine improves vascular function by overcoming deleterious effects of ADMA, a novel cardiovascular risk factor. Alternative medicine review : a journal of clinical therapeutic 20050301
Pioglitazone lowers systemic asymmetric dimethylarginine by inducing dimethylarginine dimethylaminohydrolase in rats. Hypertension research : official journal of the Japanese Society of Hypertension 20050301
Endothelial cell dysfunction and the vascular complications associated with type 2 diabetes: assessing the health of the endothelium. Vascular health and risk management 20050301
L-arginine improves the symptoms of strokelike episodes in MELAS. Neurology 20050222
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[Changes of serum asymmetric dimethylarginine in essential hypertension before and after the treatment]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050201
ADMA regulates angiogenesis: genetic and metabolic evidence. Vascular medicine (London, England) 20050201
Clinical epidemiology of major nontraditional risk factors in peritoneal dialysis patients. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050201
A reduction of endogenous asymmetric dimethylarginine contributes to the effect of captopril on endothelial dysfunction induced by homocysteine in rats. European journal of pharmacology 20050131
Cardiovascular tests: use & limits of biochemical markers - therapeutic measurements of ADMA involved in cardiovascular disorders. Current pharmaceutical design 20050101
Systemic nitric oxide production rate during hemodialysis and its relationship with nitric oxide-related factors. Blood purification 20050101
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Elevated levels of asymmetric dimethylarginine (ADMA) as a marker of cardiovascular disease and mortality. Clinical chemistry and laboratory medicine 20050101
Measurement of asymmetric dimethylarginine in plasma: methodological considerations and clinical relevance. Clinical chemistry and laboratory medicine 20050101
Concentrations of homocysteine, related metabolites and asymmetric dimethylarginine in preeclamptic women with poor nutritional status. Clinical chemistry and laboratory medicine 20050101
Asymmetric dimethylarginine, homocysteine and renal function--is there a relation? Clinical chemistry and laboratory medicine 20050101
Neurohormonal and circulatory effects of short-term treatment with enalapril and quinapril in dogs with asymptomatic mitral regurgitation. Journal of veterinary internal medicine 20050101
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The transplanted liver graft is capable of clearing asymmetric dimethylarginine. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20041201
Relationship between obesity, smoking, and the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine. Metabolism: clinical and experimental 20041201
Aspirin protected against endothelial damage induced by LDL: role of endogenous NO synthase inhibitors in rats. Acta pharmacologica Sinica 20041201
Weight loss reduces circulating asymmetrical dimethylarginine concentrations in morbidly obese women. The Journal of clinical endocrinology and metabolism 20041201
A calcium channel blocker, benidipine, improves cell membrane fluidity in human subjects via a nitric oxide-dependent mechanism. An electron paramagnetic resonance investigation. American journal of hypertension 20041201
Capillary electrophoretic and micellar electrokinetic separations of asymmetric dimethyl-L-arginine and structurally related amino acids: quantitation in human plasma. Journal of separation science 20041201
Determination of arginine and asymmetric dimethylarginine (ADMA) in human plasma by liquid chromatography/mass spectrometry with the isotope dilution technique. Journal of mass spectrometry : JMS 20041101
Asymmetric dimethyl arginine and symmetric dimethyl arginine levels in infants with persistent pulmonary hypertension of the newborn. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20041101
Association between cerebrospinal fluid levels of asymmetric dimethyl-L-arginine, an endogenous inhibitor of endothelial nitric oxide synthase, and cerebral vasospasm in a primate model of subarachnoid hemorrhage. Journal of neurosurgery 20041101
Relationship of asymmetric dimethylarginine to haemodialysis hypotension. Nitric oxide : biology and chemistry 20041101
Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl L-arginine accelerates endothelial cell senescence. Arteriosclerosis, thrombosis, and vascular biology 20041001
Asymmetric dimethylarginine (ADMA) and acute vascular events. Clinica chimica acta; international journal of clinical chemistry 20041001
Atherosclerosis and uremic retention solutes. Kidney international 20041001
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Plasma asymmetric dimethylarginine and coronary and peripheral endothelial dysfunction in hypertensive patients. American journal of hypertension 20040901
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Asymmetric dimethylarginine upregulates LOX-1 in activated macrophages: role in foam cell formation. American journal of physiology. Heart and circulatory physiology 20040801
Homocysteine, vitamin B6, and endothelial dysfunction in circulatory disorders. Stroke 20040801
17beta-estradiol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level. International journal of cardiology 20040801
The pivotal role of nitric oxide for vascular health. The Canadian journal of cardiology 20040801
Hypercholesterolemia impairs basal nitric oxide synthase turnover rate: a study investigating the conversion of L-[guanidino-(15)N(2)]-arginine to (15)N-labeled nitrate by gas chromatography--mass spectrometry. Nitric oxide : biology and chemistry 20040801
Serum homocysteine and endothelial dysfunction in circulatory disorders in women. Circulation 20040727
Sex hormones and asymmetric dimethylarginine in transplant arteriosclerosis. Circulation 20040720
Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in endothelial cells by nitric oxide deficiency. American journal of physiology. Renal physiology 20040701
Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit. The Journal of urology 20040701
Effect of simvastatin on endothelium-dependent vaso-relaxation and endogenous nitric oxide synthase inhibitor. Acta pharmacologica Sinica 20040701
Sulfhydryl angiotensin-converting enzyme inhibition induces sustained reduction of systemic oxidative stress and improves the nitric oxide pathway in patients with essential hypertension. American heart journal 20040701
Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis. Journal of hepatology 20040701
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Determination of l-arginine and NG, NG - and NG, NG' -dimethyl-L-arginine in plasma by liquid chromatography as AccQ-Fluor fluorescent derivatives. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615
Homocysteine induces oxidative stress by uncoupling of NO synthase activity through reduction of tetrahydrobiopterin. Free radical biology & medicine 20040615
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Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway. Arteriosclerosis, thrombosis, and vascular biology 20040601
Changes in the dimeric state of neuronal nitric oxide synthase affect the kinetics of secretagogue-induced insulin response. Diabetes 20040601
Effects of concentrated fine ambient particles on rat plasma levels of asymmetric dimethylarginine. Inhalation toxicology 20040601
Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA. Vascular medicine (London, England) 20040501
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Fenofibrate increases the L-arginine:ADMA ratio by increase of L-arginine concentration but has no effect on ADMA concentration. Atherosclerosis 20040401
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Plasma concentrations of asymmetric dimethylarginine (ADMA) in Colombian women with pre-eclampsia. JAMA 20040218
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Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis. Circulation 20040203
Analysis of the relationship between norepinephrine and asymmetric dimethyl arginine levels among patients with end-stage renal disease. Journal of the American Society of Nephrology : JASN 20040201
Hyperhomocysteinemia, oxidative stress, and cerebral vascular dysfunction. Stroke 20040201
Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans. Circulation 20040120
Novel cardiovascular risk factors in end-stage renal disease. Journal of the American Society of Nephrology : JASN 20040101
Atherosclerosis in dialyzed patients. Blood purification 20040101
Vascular endothelium is the organ chiefly responsible for the catabolism of plasma asymmetric dimethylarginine--an explanation for the elevation of plasma ADMA in disorders characterized by endothelial dysfunction. Medical hypotheses 20040101
Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay. Clinical chemistry and laboratory medicine 20040101
Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Circulation 20031216
Handling of asymmetrical dimethylarginine and symmetrical dimethylarginine by the rat kidney under basal conditions and during endotoxaemia. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031201
Plasma concentration of coupling factor 6 and cardiovascular events in patients with end-stage renal disease. Kidney international 20031201
Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase. Atherosclerosis. Supplements 20031201
Asymmetrical dimethylarginine (ADMA) and risk of acute coronary events. Does statin treatment influence plasma ADMA levels? Atherosclerosis. Supplements 20031201
ADMA: a novel risk factor that explains excess cardiovascular event rate in patients with end-stage renal disease. Atherosclerosis. Supplements 20031201
Plasma concentration of asymmetric dimethylarginine and the risk of coronary heart disease: rationale and design of the multicenter CARDIAC study. Atherosclerosis. Supplements 20031201
The DDAH/ADMA/NOS pathway. Atherosclerosis. Supplements 20031201
ADMA and oxidative stress. Atherosclerosis. Supplements 20031201
NO and angiogenesis. Atherosclerosis. Supplements 20031201
Hyperhomocysteinemia, endothelial dysfunction, and cardiovascular risk: the potential role of ADMA. Atherosclerosis. Supplements 20031201
Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's disease. Neurobiology of aging 20031101
Impact of vitamin E on plasma asymmetric dimethylarginine (ADMA) in chronic kidney disease (CKD): a pilot study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031101
Effect of shear stress on asymmetric dimethylarginine release from vascular endothelial cells. Hypertension (Dallas, Tex. : 1979) 20031101
When the endothelium cannot say 'NO' anymore. ADMA, an endogenous inhibitor of NO synthase, promotes cardiovascular disease. European heart journal 20031101
Plasma levels of asymmetrical dimethylarginine and adverse cardiovascular events after percutaneous coronary intervention. European heart journal 20031101
Serum concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in patients with chronic kidney diseases. Clinica chimica acta; international journal of clinical chemistry 20031001
Asymmetrical dimethylarginine and multiple organ failure. Clinical nutrition (Edinburgh, Scotland) 20031001
Elevated plasma and urine levels of ADMA and 15(S)-8-iso-PGF2alpha in end-stage liver disease. Hepatology (Baltimore, Md.) 20031001
The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor. Cardiovascular research 20031001
Asymmetrical dimethylarginine: a novel risk factor for coronary artery disease. Clinical cardiology 20031001
Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. Circulation 20030930
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension. Circulation 20030923
A novel mechanism for pulmonary arterial hypertension? Circulation 20030923
Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype. Biochemical and biophysical research communications 20030905
Effect of hormone replacement therapy on plasma levels of the cardiovascular risk factor asymmetric dimethylarginine: a randomized, placebo-controlled 12-week study in healthy early postmenopausal women. The Journal of clinical endocrinology and metabolism 20030901
High plasma level of asymmetric dimethylarginine in patients with acutely exacerbated congestive heart failure: role in reduction of plasma nitric oxide level. Heart and vessels 20030901
Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine. Circulation 20030826
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Elevated levels of the serum endogenous inhibitor of nitric oxide synthase and metabolic control in rats with streptozotocin-induced diabetes. Journal of cardiovascular pharmacology 20030801
Oestrogen replacement therapy lowers plasma levels of asymmetrical dimethylarginine in healthy postmenopausal women. Clinical science (London, England : 1979) 20030701
Oestrogen and the cardiovascular system. Clinical science (London, England : 1979) 20030701
High-performance liquid chromatographic assay of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine in human plasma by derivatization with naphthalene-2,3-dicarboxaldehyde. Analytical biochemistry 20030701
Functional changes in the ageing kidney: is there a role for asymmetric dimethylarginine? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030701
Hyperhomocysteinaemia is not associated with increased levels of asymmetric dimethylarginine in patients with ischaemic heart disease. European journal of clinical investigation 20030701
Metabolism-based inactivation of neuronal nitric-oxide synthase by components of cigarette and cigarette smoke. Drug metabolism and disposition: the biological fate of chemicals 20030701
Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women. Journal of hypertension 20030701
Increased asymmetric dimethylarginine and endothelin 1 levels in secondary Raynaud's phenomenon: implications for vascular dysfunction and progression of disease. Arthritis and rheumatism 20030701
The protective effects of monophosphoryl lipid A on the ischemic myocardium and endothelium in rats. Cardiovascular drugs and therapy 20030701
Potential mechanisms of impaired endothelial function in arterial hypertension and hypercholesterolemia. Current hypertension reports 20030601
Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia. Lancet (London, England) 20030503
Asymmetric dimethylarginine: a cardiovascular risk factor in renal disease? Kidney international. Supplement 20030501
ADMA: a critical cardio-renal link in heart failure? European journal of clinical investigation 20030501
Endogenous nitric oxide synthase inhibitors and renal perfusion in patients with heart failure. European journal of clinical investigation 20030501
Effects of simvastatin and L-arginine on vasodilation, nitric oxide metabolites and endogenous NOS inhibitors in hypercholesterolemic subjects. Free radical research 20030501
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Cardiac allograft vasculopathy and dysregulation of the NO synthase pathway. Arteriosclerosis, thrombosis, and vascular biology 20030401
Significance of asymmetric dimethylarginine (ADMA) concentrations during coronary circulation in patients with vasospastic angina. Circulation journal : official journal of the Japanese Circulation Society 20030401
Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia. Circulation 20030304
Folic acid treatment reduces elevated plasma levels of asymmetric dimethylarginine in hyperhomocysteinaemic subjects. The British journal of nutrition 20030301
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Regulation of cytokine-induced nitric oxide synthesis by asymmetric dimethylarginine: role of dimethylarginine dimethylaminohydrolase. Circulation research 20030207
Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin. Atherosclerosis 20030201
Effect of high-dose statin treatment on plasma concentrations of endogenous nitric oxide synthase inhibitors. Journal of cardiovascular pharmacology 20030201
The liver is an important organ in the metabolism of asymmetrical dimethylarginine (ADMA). Clinical nutrition (Edinburgh, Scotland) 20030201
Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality. Clinical nutrition (Edinburgh, Scotland) 20030201
The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis. Clinical nutrition (Edinburgh, Scotland) 20030201
Acute intravenous L-arginine infusion decreases endothelin-1 levels and improves endothelial function in patients with angina pectoris and normal coronary arteriograms: correlation with asymmetric dimethylarginine levels. Circulation 20030128
Reduction of total homocysteine levels by oral folic acid fails to improve endothelial function in children with chronic renal failure. Circulation 20030107
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. Cardiovascular research 20030101
Presence of methylated arginine derivatives in orthotopic human liver transplantation: relevance for liver function. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030101
Asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, in maternal and fetal circulation. Journal of the Society for Gynecologic Investigation 20030101
New markers of accelerated atherosclerosis in end-stage renal disease. Journal of nephrology 20030101
Asymmetric dimethylarginine and total homocysteine in plasma after oral methionine loading. Scandinavian journal of clinical and laboratory investigation 20030101
Asymmetric dimethylarginine (ADMA) modulates endothelial function--therapeutic implications. Vascular medicine (London, England) 20030101
Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults. Vascular medicine (London, England) 20030101
Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in hyperthyroid patients. The Journal of clinical endocrinology and metabolism 20021201
Asymmetric dimethylarginine (ADMA): a potential link between endothelial dysfunction and cardiovascular diseases in insulin resistance syndrome? Diabetologia 20021201
Endothelium-dependent vasorelaxation and the expression of calcitonin gene-related peptide in aged rats. Neuropeptides 20021201
Hypertension in relation to nitric oxide, asymmetric dimethylarginine, and inflammation: different patterns in heart transplant recipients and individuals with essential hypertension. Transplantation 20021127
Effect of oestrone on membrane fluidity of erythrocytes is mediated by a nitric oxide-dependent pathway: An electron paramagnetic resonance study. Clinical and experimental pharmacology & physiology 20021101
Long-term angiotensin-converting enzyme inhibition reduces plasma asymmetric dimethylarginine and improves endothelial nitric oxide bioavailability and coronary microvascular function in patients with syndrome X. The American journal of cardiology 20021101
Net renal extraction of asymmetrical (ADMA) and symmetrical (SDMA) dimethylarginine in fasting humans. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021101
Plasma asymmetric dimethylarginine and hyperemic myocardial blood flow in young subjects with borderline hypertension or familial hypercholesterolemia. Journal of the American College of Cardiology 20021002
Circulating concentrations of asymmetrical dimethyl-L-arginine are increased in women with previous gestational diabetes. Diabetologia 20021001
Leptin improves membrane fluidity of erythrocytes in humans via a nitric oxide-dependent mechanism--an electron paramagnetic resonance investigation. Biochemical and biophysical research communications 20020927
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Alzheimer's disease is not associated with altered concentrations of the nitric oxide synthase inhibitor asymmetric dimethylarginine in cerebrospinal fluid. Journal of neural transmission (Vienna, Austria : 1996) 20020901
Angiotensin-converting enzyme activity is involved in the mechanism of increased endogenous nitric oxide synthase inhibitor in patients with type 2 diabetes mellitus. Circulation journal : official journal of the Japanese Circulation Society 20020901
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Reduced nitric oxide synthase activity in rats with chronic renal disease due to glomerulonephritis. Kidney international 20020801
Synergistic role of progesterone and nitric oxide in the regulation of membrane fluidity of erythrocytes in humans: an electron paramagnetic resonance investigation. American journal of hypertension 20020801
Blunted acetylcholine relaxation and nitric oxide release in arteries from renal hypertensive rats. Journal of hypertension 20020801
Endothelin stimulates an endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine, in experimental heart failure. Clinical science (London, England : 1979) 20020801
Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes. Metabolism: clinical and experimental 20020701
Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients. Kidney international 20020701
Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension. American journal of hypertension 20020701
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia. American journal of physiology. Regulatory, integrative and comparative physiology 20020601
Effect of age on bone mineral density and the serum concentration of endogenous nitric oxide synthase inhibitors in rats. Comparative medicine 20020601
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[Relationship between serum asymmetric dimethylarginine and blood pressure in patients with chronic renal failure]. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20020428
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all-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase. Circulation research 20020419
Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography. Analytical biochemistry 20020415
Myocardial proteome analysis reveals reduced NOS inhibition and enhanced glycolytic capacity in areas of low local blood flow. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020401
Helicobacter pylori infection inhibits antral mucosal nitric oxide production in humans. Scandinavian journal of gastroenterology 20020401
Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA 20020320
Insulin resistance, ADMA levels, and cardiovascular disease. JAMA 20020320
Nitric oxide synthase and hypertension. Current opinion in nephrology and hypertension 20020301
Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level. British journal of pharmacology 20020301
Mechanisms of dysfunction of the nitric oxide pathway in vascular diseases. Nitric oxide : biology and chemistry 20020301
Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries. Journal of cardiovascular pharmacology 20020201
Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease. Journal of the American Society of Nephrology : JASN 20020201
Hemodynamic changes during hemodialysis: role of nitric oxide and endothelin. Kidney international 20020201
Marked increase of asymmetric dimethylarginine in patients with incipient primary chronic renal disease. Journal of the American Society of Nephrology : JASN 20020101
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Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease. Blood purification 20020101
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Homocysteine and ADMA--emerging risk factors for cardiovascular disease? Blood pressure 20020101
Acute administration of L-arginine does not improve arterial endothelial function in chronic renal failure. Kidney international 20011201
Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation 20011120
Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus. The American journal of cardiology 20011115
Effect of asymmetric dimethylarginine on osteoblastic differentiation. Kidney international 20011101
Reduction in asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in the cerebrospinal fluid during aging and in patients with Alzheimer's disease. Neuroscience letters 20011026
Elevated serum endogenous inhibitor of nitric oxide synthase and endothelial dysfunction in aged rats. Clinical and experimental pharmacology & physiology 20011001
Elevated levels of plasma homocyst(e)ine and asymmetric dimethylarginine in elderly patients with stroke. Atherosclerosis 20011001
High NaCl intake decreases both flow-induced dilation and pressure-induced myogenic tone in resistance arteries from normotensive rats: involvement of cyclooxygenase-2. Pharmacology & toxicology 20011001
ADMA (asymmetric dimethylarginine): an atherosclerotic disease mediating agent in patients with renal disease? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010901
Dialysis improves endothelial function in humans. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010901
PRMT5 (Janus kinase-binding protein 1) catalyzes the formation of symmetric dimethylarginine residues in proteins. The Journal of biological chemistry 20010831
Electron paramagnetic resonance investigation on modulatory effect of 17beta-estradiol on membrane fluidity of erythrocytes in postmenopausal women. Arteriosclerosis, thrombosis, and vascular biology 20010801
Endothelium-dependent vasodilation is independent of the plasma L-arginine/ADMA ratio in men with stable angina: lack of effect of oral L-arginine on endothelial function, oxidative stress and exercise performance. Journal of the American College of Cardiology 20010801
Levels of dimethylarginines and cytokines in mild and severe preeclampsia. Acta obstetricia et gynecologica Scandinavica 20010701
Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine. Journal of the American College of Cardiology 20010701
Dimethylarginines in chronic renal failure. Journal of clinical pathology 20010601
Methylation of histone H3 by coactivator-associated arginine methyltransferase 1. Biochemistry 20010515
Atherogenesis and the arginine hypothesis. Current atherosclerosis reports 20010501
SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets. Molecular cell 20010501
Estriol improves membrane fluidity of erythrocytes by the nitric oxide-dependent mechanism: an electron paramagnetic resonance study. Hypertension research : official journal of the Japanese Society of Hypertension 20010501
Circulating endothelial nitric oxide synthase inhibitory factor in some patients with chronic renal disease. Kidney international 20010401
Plasma levels of asymmetrical dimethyl-L-arginine in patients with congenital heart disease and pulmonary hypertension. Journal of cardiovascular pharmacology 20010401
Relationship of asymmetric dimethylarginine to dialysis treatment and atherosclerotic disease. Kidney international. Supplement 20010201
Serum concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in renal failure patients. Kidney international. Supplement 20010201
Increased reduction of dimethylarginines and lowered interdialytic blood pressure by the use of biocompatible membranes. Kidney international. Supplement 20010201
Comment: the asymmetrical dimethylarginine/dimethylarginine dimethylaminohydrolase pathway in the regulation of nitric oxide generation. Clinical science (London, England : 1979) 20010201
Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans. Clinical science (London, England : 1979) 20010201
Reversible sequestration of nitric oxide by hemoglobin during hemodialysis in end-stage renal disease. The American journal of the medical sciences 20010201
The nitric oxide system and cortisol-induced hypertension in humans. Clinical and experimental pharmacology & physiology 19981101
Protein and cDNA sequence of a glycine-rich, dimethylarginine-containing region located near the carboxyl-terminal end of nucleolin (C23 and 100 kDa). The Journal of biological chemistry 19860715
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