 
                Butanedioic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine (1:1)
| Title | Journal | 
|---|---|
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| The antipsychotic drug loxapine is an opener of the sodium-activated potassium channel slack (Slo2.2). | The Journal of pharmacology and experimental therapeutics 20120301 | 
| Inhaled loxapine for agitation revisited: focus on effect sizes from 2 Phase III randomised controlled trials in persons with schizophrenia or bipolar disorder. | International journal of clinical practice 20120301 | 
| Loxapine P-glycoprotein interactions in vitro. | Drug metabolism letters 20120301 | 
| Rapid acute treatment of agitation in patients with bipolar I disorder: a multicenter, randomized, placebo-controlled clinical trial with inhaled loxapine. | Bipolar disorders 20120201 | 
| [RÉALITÉ LT, a pharmacoepidemiological study of semiology and therapeutic strategy of patients with schizophrenia treated by antipsychotic loxapine in routine clinical practice]. | L'Encephale 20120201 | 
| Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC-MS/MS. | Journal of pharmaceutical and biomedical analysis 20120125 | 
| Now take a deep breath: inhaled loxapine for the treatment of acute agitation. | Journal of psychosocial nursing and mental health services 20120101 | 
| Neuroleptic malignant syndrome-like reaction precipitated by antipsychotics in a patient with gamma-butyrolactone withdrawal. | Journal of addiction medicine 20111201 | 
| Swallowing difficulties: a prognostic signpost. | Canadian family physician Medecin de famille canadien 20111201 | 
| Efficacy and safety of loxapine for inhalation in the treatment of agitation in patients with schizophrenia: a randomized, double-blind, placebo-controlled trial. | The Journal of clinical psychiatry 20111001 | 
| In vitro identification of the human cytochrome p450 enzymes involved in the oxidative metabolism of loxapine. | Biopharmaceutics & drug disposition 20111001 | 
| The pharmacoepidemiology of antipsychotics for adults with schizophrenia in Canada, 2005 to 2009. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20111001 | 
| 'Extended' antipsychotic dosing in the maintenance treatment of schizophrenia: a double-blind, placebo-controlled trial. | The Journal of clinical psychiatry 20110801 | 
| Combination loxapine and aripiprazole for refractory hallucinations in schizophrenia. | The Annals of pharmacotherapy 20110701 | 
| Modelling schizophrenia using human induced pluripotent stem cells. | Nature 20110512 | 
| The benefits of an active control arm. | The British journal of psychiatry : the journal of mental science 20110401 | 
| Aerosolised antipsychotic assuages agitation: inhaled loxapine for agitation associated with schizophrenia or bipolar disorder. | International journal of clinical practice 20110301 | 
| Interaction of clozapine and its nitrenium ion with rat D2 dopamine receptors: in vitro binding and computational study. | Journal of computer-aided molecular design 20110201 | 
| In vitro aerosol characterization of Staccato(®) Loxapine. | International journal of pharmaceutics 20110117 | 
| Rapid acute treatment of agitation in individuals with schizophrenia: multicentre, randomised, placebo-controlled study of inhaled loxapine. | The British journal of psychiatry : the journal of mental science 20110101 | 
| Validation of HPLC-MS/MS methods for analysis of loxapine, amoxapine, 7-OH-loxapine, 8-OH-loxapine and loxapine N-oxide in human plasma. | Bioanalysis 20101201 | 
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 | 
| In vitro aerosol deposition in the oropharyngeal region for Staccato loxapine. | Journal of aerosol medicine and pulmonary drug delivery 20100801 | 
| Pharmacokinetics of loxapine following inhalation of a thermally generated aerosol in healthy volunteers. | Journal of clinical pharmacology 20100201 | 
| [Catatonia in a 14 year-old girl: treatment with clorazepam and carbamazepine, a 10-year follow-up]. | L'Encephale 20100201 | 
| Beneficial effects of loxapine on agitation and breathing patterns during weaning from mechanical ventilation. | Critical care (London, England) 20100101 | 
| Psychotic woman with painful abdominal distension. Life-threatening psychotropic drug-induced gastrointestinal hypomotility. | Annals of emergency medicine 20091101 | 
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 | 
| Rapid liquid chromatography/tandem mass spectrometer (LCMS) method for clozapine and its metabolite N-desmethyl clozapine (norclozapine) in human serum. | Journal of clinical laboratory analysis 20090101 | 
| Loxapine for schizophrenia. | The Cochrane database of systematic reviews 20071017 | 
| Effect of loxapine on electrical brain activity, intracranial pressure, and middle cerebral artery flow velocity in traumatic brain-injured patients. | Neurocritical care 20070101 | 
| Lack of enhanced effect of antipsychotics combined with fluvoxamine on acetylcholine release in rat prefrontal cortex. | Journal of pharmacological sciences 20061201 | 
| Loxapine treatment in an autistic child with aggressive behavior: therapeutic challenges. | Journal of child and adolescent psychopharmacology 20061001 | 
| Adjunctive topiramate in ultradian cycling bipolar disorder: case report with 3-year follow-up. | European psychiatry : the journal of the Association of European Psychiatrists 20060601 | 
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 | 
| Increasing psychosis in a patient switched from clozaril to generic clozapine. | The American journal of psychiatry 20060401 | 
| [Therapeutics approach of adult patients with acute and chronic psychotic states: REALITE survey]. | L'Encephale 20060101 | 
| Contrasting loxapine to its isomer isoloxapine--the critical role of in vivo D2 blockade in determining atypicality. | Schizophrenia research 20050915 | 
| Atypical and typical antipsychotic drug interactions with the dopamine D2 receptor. | European journal of medicinal chemistry 20050201 | 
| Chlorpromazine and loxapine reduce interleukin-1beta and interleukin-2 release by rat mixed glial and microglial cell cultures. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050101 | 
| Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors. | European journal of pharmacology 20040714 | 
| Transient hyperproinsulinemia during treatment with clozapine and amisulpride. | The Journal of clinical psychiatry 20040601 | 
| [Agranulocytosis induced by loxapine in an elderly patient: a case study]. | Therapie 20040101 | 
| Neuroleptic malignant syndrome: case report and discussion. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030902 | 
| A comparison of the effects of loxapine with ziprasidone and thioridazine on the release of dopamine and acetylcholine in the prefrontal cortex and nucleus accumbens. | Psychopharmacology 20030501 | 
| Human genetic variations in the 5HT2A receptor: a single nucleotide polymorphism identified with altered response to clozapine. | Pharmacogenetics 20030201 | 
| Effect of loxapine on peripheral dopamine-like and serotonin receptors in patients with schizophrenia. | Journal of psychiatry & neuroscience : JPN 20030101 | 
| Loxapine versus olanzapine in the treatment of delirium following traumatic brain injury. | NeuroRehabilitation 20030101 | 
| [Survey of management methods for patients in a state of agitation at admission and emergency departments in France]. | L'Encephale 20030101 | 
| Interspecies variability and drug interactions of loxapine metabolism in liver microsomes. | European journal of drug metabolism and pharmacokinetics 20030101 | 
| Discriminative stimulus properties in rats of the novel antipsychotic quetiapine. | Experimental and clinical psychopharmacology 20021101 | 
| [Self-poisoning with Datura stramonium. 3 case reports]. | Presse medicale (Paris, France : 1983) 20020119 | 
| Re: Neuroleptic malignant syndrome associated with quetiapine. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20010501 | 
| Loxapine side-effects: 3 case reports of hyperleukocytosis. | Therapie 20010101 | 
| Does loxapine have 'atypical' properties? Clinical evidence. | The Journal of clinical psychiatry 19990101 | 
| The role of alpha2-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat. | British journal of pharmacology 19980801 | 
| Clozapine inhibits catalepsy induced by olanzapine and loxapine, but prolongs catalepsy induced by SCH 23390 in rats. | Naunyn-Schmiedeberg's archives of pharmacology 19970301 | 
| Emergence of symptoms of Tourette's syndrome during fluvoxamine treatment of obsessive-compulsive disorder. | The British journal of psychiatry : the journal of mental science 19940601 | 
| Simultaneous quantitation of loxapine, amoxapine and their 7- and 8-hydroxy metabolites in plasma by high-performance liquid chromatography. | Journal of chromatography 19910308 | 
| Loxapine-lorazepam-induced hypotension and stupor. | Journal of clinical psychopharmacology 19890601 | 
| Neurotoxicity resulting from a combination of lithium and loxapine. | The Journal of clinical psychiatry 19890501 | 
| Rapid tranquilization: a comparison of thiothixene with loxapine. | The Journal of clinical psychiatry 19860601 | 
| Drug interactions on spontaneous locomotor activity in rats. Neuroleptics and amphetamine-induced hyperactivity. | Neuropharmacology 19840801 | 
| Loxapine versus chlorpromazine in paranoid schizophrenia: a double-blind study. | The Journal of clinical psychiatry 19840401 | 
| Neuroleptic-induced catatonia: case report. | The Journal of clinical psychiatry 19830801 | 
| Neuroleptic malignant syndrome associated with loxapine. | The Journal of clinical psychiatry 19830101 | 
| Efficacy of antipsychotic medications in behaviorally disturbed dementia patients. | The American journal of psychiatry 19820901 | 
| Loxapine succinate as initial treatment of hostile and aggressive schizophrenic criminal offenders. | Journal of clinical pharmacology 19820101 | 
| Seizures induced by acute loxapine overdose. | The American journal of psychiatry 19810801 | 
| Evaluations of loxapine succinate in the ambulatory treatment of acute schizophrenic episodes. | International pharmacopsychiatry 19800101 | 
| [Loxapine succinate: a new neuroleptic]. | L'Encephale 19790101 | 
| A two year trial of loxapine succinate in chronic psychotic patients. | Diseases of the nervous system 19760501 | 
| Treatment of acute psychotic patients with loxapine parenterally. | Current therapeutic research, clinical and experimental 19760201 | 
| [The assessment of neuroleptogenic extrapyramidal syndroms in psychopharmacological research (author's transl)]. | Pharmakopsychiatrie, Neuro-Psychopharmakologie 19750101 |