Home Aminos 9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-

9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-

CAS No.:
27591-97-5
Catalog Number:
AG002U6A
Molecular Formula:
C25H34N2O3
Molecular Weight:
410.5491
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%(HPLC)
In Stock USA
United States
$114
- +
25mg
99%(HPLC)
In Stock USA
United States
$350
- +
100mg
99%(HPLC)
In Stock USA
United States
$1176
- +
Product Description
Catalog Number:
AG002U6A
Chemical Name:
9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-
CAS Number:
27591-97-5
Molecular Formula:
C25H34N2O3
Molecular Weight:
410.5491
MDL Number:
MFCD00866953
IUPAC Name:
2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one
InChI:
InChI=1S/C25H34N2O3/c1-5-26(6-2)13-15-29-19-9-11-21-22-12-10-20(30-16-14-27(7-3)8-4)18-24(22)25(28)23(21)17-19/h9-12,17-18H,5-8,13-16H2,1-4H3
InChI Key:
MPMFCABZENCRHV-UHFFFAOYSA-N
SMILES:
CCN(CCOc1ccc2c(c1)C(=O)c1c2ccc(c1)OCCN(CC)CC)CC
UNII:
O6W7VEW6KS
NSC Number:
759311
Properties
Complexity:
477  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
410.257g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
410.558g/mol
Monoisotopic Mass:
410.257g/mol
Rotatable Bond Count:
12  
Topological Polar Surface Area:
42A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.7  
Literature
Title Journal
Why are most phospholipidosis inducers also hERG blockers? Archives of toxicology 20171201
Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. Toxicological sciences : an official journal of the Society of Toxicology 20120501
SAR of α7 nicotinic receptor agonists derived from tilorone: exploration of a novel nicotinic pharmacophore. Bioorganic & medicinal chemistry letters 20120215
[The antiviral activity of diphenyl derivatives in different model systems]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20120101
Dose-dependent IFN-stimulating and immunomodulating properties of 6H-indolo[2,3-B] quinoxaline derivatives. Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20120101
[Perspectives of prevention and treatment of herpes symplex with regular recurrence]. Terapevticheskii arkhiv 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Performance of tiloronoxim and tilorone determination in human blood by HPLC-MS/MS: method validation, uncertainty assessment and its application to a pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201
α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease. The open medicinal chemistry journal 20100101
Synthesis and affinity to DNA of phenylbenzoimidazoles and benzoimidazo[1,2-c]quinazolines. European journal of medicinal chemistry 20090801
Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury. Annals of the New York Academy of Sciences 20081201
Simultaneous quantification of tiloronoxim and tilorone in human urine by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115
Chemically induced accumulation of GAGs delays PrP(Sc) clearance but prolongs prion disease incubation time. Cellular and molecular neurobiology 20081101
alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues. British journal of pharmacology 20080301
DNA binding of tilorone: 1H NMR and calorimetric studies of the intercalation. Biochemistry 20070710
[Interferonogenic activity of amixin analogs and diphenyl derivatives]. Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20070101
Possible implication of macrophages in the regulation of cytochrome P450 activities in carp (Cyprinus carpio). Fish & shellfish immunology 20060701
[Individual changes of gene expression in the interferon system in human blood cells due to amixin and cycloferon]. Voprosy virusologii 20050101
[Interferon status of patients with non-specific ulcerous colitis and its correction with interferon inducers]. Terapevticheskii arkhiv 20020101
[Intestinal microflora in rats under the conditions of a chronic toxic lesion of the liver]. Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20020101
Correlations between in vitro effects of preparations of interferon and its inducers on blood cells in patients with multiple sclerosis. Bulletin of experimental biology and medicine 20010401
Antiviral and interferon-inducing properties of interferon inducers administered with prostaglandins. Antimicrobial agents and chemotherapy 19800301
Effects of tilorone hydrochloride on experimental flavivirus infections in mice. Acta virologica 19770301
Antiviral activity of BL-3849A, a low-molecular-weight oral interferon inducer. Antimicrobial agents and chemotherapy 19761001
Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 3. 2,7-Bis(aminoacyl)fluorenes and -fluorenones. Journal of medicinal chemistry 19740801
Antiviral activity and induction of interferon-like substance by quinacrine and acranil. Antimicrobial agents and chemotherapy 19730501
Properties