Home Carboxys 1-Aminocyclohexanecarboxylic acid

1-Aminocyclohexanecarboxylic acid

CAS No.:
2756-85-6
Catalog Number:
AG002U2H
Molecular Formula:
C7H13NO2
Molecular Weight:
143.1836
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$13
- +
25g
98%
In Stock USA
United States
$38
- +
100g
98%
In Stock USA
United States
$132
- +
500g
98%
In Stock USA
United States
$475
- +
Product Description
Catalog Number:
AG002U2H
Chemical Name:
1-Aminocyclohexanecarboxylic acid
CAS Number:
2756-85-6
Molecular Formula:
C7H13NO2
Molecular Weight:
143.1836
MDL Number:
MFCD00001487
IUPAC Name:
1-aminocyclohexane-1-carboxylic acid
InChI:
InChI=1S/C7H13NO2/c8-7(6(9)10)4-2-1-3-5-7/h1-5,8H2,(H,9,10)
InChI Key:
WOXWUZCRWJWTRT-UHFFFAOYSA-N
SMILES:
OC(=O)C1(N)CCCCC1
EC Number:
220-411-0
UNII:
1SE3HD391H
NSC Number:
9059
Properties
Complexity:
139  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
143.095g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
143.186g/mol
Monoisotopic Mass:
143.095g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
63.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.9  
Literature
Title Journal
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Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Drug design, in vitro pharmacology, and structure-activity relationships of 3-acylamino-2-aminopropionic acid derivatives, a novel class of partial agonists at the glycine site on the N-methyl-D-aspartate (NMDA) receptor complex. Journal of medicinal chemistry 20090827
Redetermination of 1-carboxy-cyclo-hexan-1-aminium chloride. Acta crystallographica. Section E, Structure reports online 20090201
Synthesis and utilization of chiral alpha-methylated alpha-amino acids with a carboxyalkyl side chain in the design of novel Grb2-SH2 peptide inhibitors free of phosphotyrosine. Journal of medicinal chemistry 20081023
cis-3-(tert-Butoxy-carbonyl-amino)cyclo-hexa-necarboxylic acid. Acta crystallographica. Section E, Structure reports online 20080901
Application of 1-aminocyclohexane carboxylic acid to protein nanostructure computer design. Journal of chemical information and modeling 20080201
An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides. PloS one 20070101
New bradykinin analogues substituted in positions 7 and 8 with sterically restricted 1-aminocyclopentane-1-carboxylic acid. Journal of peptide science : an official publication of the European Peptide Society 20061201
Application of azide-alkyne cycloaddition 'click chemistry' for the synthesis of Grb2 SH2 domain-binding macrocycles. Bioorganic & medicinal chemistry letters 20061015
Raman and surface-enhanced Raman spectroscopy investigation of vasopressin analogues containing 1-aminocyclohexane-1-carboxylic acid residue. Biopolymers 20061005
New bradykinin analogues modified in the C-terminal part with sterically restricted 1-aminocyclohexane-1-carboxylic acid. Journal of medicinal chemistry 20051215
Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K. Journal of medicinal chemistry 20051201
The influence of 1-aminocyclopentane-1-carboxylic acid at position 2 or 3 of AVP and its analogues on their pharmacological properties. Journal of peptide science : an official publication of the European Peptide Society 20050901
Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics. Journal of medicinal chemistry 20050210
Bioactive N-terminal undecapeptides derived from parathyroid hormone: the role of alpha-helicity. The journal of peptide research : official journal of the American Peptide Society 20050101
Highly potent 1-aminocyclohexane-1-carboxylic acid substituted V2 agonists of arginine vasopressin. Journal of medicinal chemistry 20041118
Influence of 1-aminocyclohexane-1-carboxylic acid in position 2 or 3 of AVP and its analogues on their pharmacological properties. The journal of peptide research : official journal of the American Peptide Society 20030801
The structure of an endomorphin analogue incorporating 1-aminocyclohexane-1-carboxlylic acid for proline is similar to the beta-turn of Leu-enkephalin. Biochemical and biophysical research communications 20020913
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Nitroxyl peptides as catalysts of enantioselective oxidations. Chemistry (Weinheim an der Bergstrasse, Germany) 20020104
Amphipathic control of the 3(10)-/alpha-helix equilibrium in synthetic peptides. The journal of peptide research : official journal of the American Peptide Society 20010801
Chloramine-T in radiolabeling techniques. IV. Penta-O-acetyl-N-chloro-N-methylglucamine as an oxidizing agent in radiolabelling techniques. Analytical biochemistry 20010101
Crystal-state conformation of Calpha,alpha-dialkylated peptides containing chiral beta-homo-residues. Journal of peptide science : an official publication of the European Peptide Society 20010101
Properties