Home Other Building Blocks Sincalide

Sincalide

CAS No.:
25126-32-3
Catalog Number:
AG002QKR
Molecular Formula:
C49H62N10O16S3
Molecular Weight:
1143.2690
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$193
- +
5mg
≥98%
1 week
United States
$689
- +
Product Description
Catalog Number:
AG002QKR
Chemical Name:
Sincalide
CAS Number:
25126-32-3
Molecular Formula:
C49H62N10O16S3
Molecular Weight:
1143.2690
MDL Number:
MFCD00079849
IUPAC Name:
(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-(4-sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid
InChI:
InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1
InChI Key:
IZTQOLKUZKXIRV-YRVFCXMDSA-N
SMILES:
CSCC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1ccccc1)CC(=O)O)CCSC)Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)N)Cc1ccc(cc1)OS(=O)(=O)O
EC Number:
246-639-0
UNII:
M03GIQ7Z6P
Properties
Complexity:
2180  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Defined Bond Stereocenter Count:
0
Exact Mass:
1142.351g/mol
Formal Charge:
0
Heavy Atom Count:
78  
Hydrogen Bond Acceptor Count:
19  
Hydrogen Bond Donor Count:
13  
Isotope Atom Count:
0
Molecular Weight:
1143.269g/mol
Monoisotopic Mass:
1142.351g/mol
Rotatable Bond Count:
33  
Topological Polar Surface Area:
486A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.6  
Literature
Title Journal
Promotion of SIRT1 protein degradation and lower SIRT1 gene expression via reactive oxygen species is involved in Sb-induced apoptosis in BEAS-2b cells. Toxicology letters 20181015
27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells. Neurotoxicology 20170301
Therapeutic effects of quercetin on early inflammation in hypertriglyceridemia-related acute pancreatitis and its mechanism. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20160101
[Effect of PON1 overexpression on mouse diaphragmatic muscle cells injury caused by acute dichlorvos poisoning]. Zhonghua yi xue za zhi 20150922
Artesunate induces apoptosis through caspase-dependent and -independent mitochondrial pathways in human myelodysplastic syndrome SKM-1 cells. Chemico-biological interactions 20140805
Interaction of the bioactive flavonol, icariin, with the essential human solute carrier transporters. Journal of biochemical and molecular toxicology 20140201
Cholecystokinin-octapeptide restored morphine-induced hippocampal long-term potentiation impairment in rats. Neuroscience letters 20140124
Effect of methamphetamine on the microglial damage: role of potassium channel Kv1.3. PloS one 20140101
Modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity. Brain research bulletin 20121201
Cocaine- and amphetamine-regulated transcript is the neurotransmitter regulating the action of cholecystokinin and leptin on short-term satiety in rats. American journal of physiology. Gastrointestinal and liver physiology 20121101
Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes. Diabetologia 20121001
Tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone initiates and enhances pancreatitis responses. American journal of physiology. Gastrointestinal and liver physiology 20120915
Effect of melatonin on α-synuclein self-assembly and cytotoxicity. Neurobiology of aging 20120901
Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats. Gastroenterology 20120901
[Direct contact with bone stromal HS-5 cells reduces the sensitivity of HEL to drugs]. Zhongguo shi yan xue ye xue za zhi 20120801
Synthesis and cytotoxicity testing of new amido-substituted triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) derivatives. Molecules (Basel, Switzerland) 20120725
Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1α/P-gp and MRP1 signaling pathway in vitro and in vivo. Journal of cellular biochemistry 20120701
The biological behavior of SDF-1/CXCR4 in patients with myelodysplastic syndrome. Medical oncology (Northwood, London, England) 20120601
Simvastatin attenuated cerebrovascular cell proliferation in the development of hypertension through Rho/Rho-kinase pathway. Journal of cardiovascular pharmacology 20120601
An active extract of Ulmus pumila inhibits adipogenesis through regulation of cell cycle progression in 3T3-L1 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry 20120524
Neddylation positively regulates the ubiquitin E3 ligase activity of parkin. Journal of neuroscience research 20120501
An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. The Journal of clinical investigation 20120402
Feeding-suppressive mechanism of sulfated cholecystokinin (26-33) in chicks. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20120401
[Effects of anhydroicaritin on the immunologic function of mouse macrophages]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20120401
CCK receptors-related signaling involved in nitric oxide production caused by gastrin 17 in porcine coronary endothelial cells. Molecular and cellular endocrinology 20120305
Resveratrol mobilizes Ca2+ from intracellular stores and induces c-Jun N-terminal kinase activation in tumoral AR42J cells. Molecular and cellular biochemistry 20120301
The cytocompatability of polyhydroxyalkanoates coated with a fusion protein of PHA repressor protein (PhaR) and Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) polypeptide. Biomaterials 20120301
The effect of matrix extracellular phosphoglycoprotein and its downstream osteogenesis-related gene expression on the proliferation and differentiation of human dental pulp cells. Journal of endodontics 20120301
The effects of exogenous CCK-8 on the acquisition and expression of morphine-induced CPP. Neuroscience letters 20120221
Duodenal myotomy blocks reduction of meal size and prolongation of intermeal interval by cholecystokinin. Physiology & behavior 20120201
Systemic cholecystokinin amplifies vago-vagal reflex responses recorded in vagal motor neurones. The Journal of physiology 20120201
The effect of exogenous apelin on the secretion of pancreatic juice in anaesthetized rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120201
Circulating GLP-1 and CCK-8 reduce food intake by capsaicin-insensitive, nonvagal mechanisms. American journal of physiology. Regulatory, integrative and comparative physiology 20120115
Biphasic regulation of the acute μ-withdrawal and CCk-8 contracture responses by the ORL-1 system in guinea pig ileum. Pharmacological research 20120101
Dicyclomine: cause of abnormally decreased gall bladder ejection with sincalide-stimulated hepatobiliary scintigraphy. Clinical nuclear medicine 20120101
Role of calcium in activation of hyperpolarization-activated cyclic nucleotide-gated channels caused by cholecystokinin octapeptide in interstitial cells of cajal. Digestion 20120101
The PBDE-209 exposure during pregnancy and lactation impairs immune function in rats. Mediators of inflammation 20120101
Role of centromere protein H and Ki67 in relapse-free survival of patients after primary surgery for hypopharyngeal cancer. Asian Pacific journal of cancer prevention : APJCP 20120101
Cholecystokinin enhances visceral pain-related affective memory via vagal afferent pathway in rats. Molecular brain 20120101
Cholecystokinin receptor-1 mediates the inhibitory effects of exogenous cholecystokinin octapeptide on cellular morphine dependence. BMC neuroscience 20120101
Effects of exogenous cholecystokinin octapeptide on acquisition of naloxone precipitated withdrawal induced conditioned place aversion in rats. PloS one 20120101
In vitro toxicity evaluation of 25-nm anatase TiO2 nanoparticles in immortalized keratinocyte cells. Biological trace element research 20111201
Tracing of the Bile-chemotactic migration of juvenile Clonorchis sinensis in rabbits by PET-CT. PLoS neglected tropical diseases 20111201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Cholecystokinin octapeptide inhibits immunoglobulin G1 production of lipopolysaccharide-activated B cells. International immunopharmacology 20111101
Block by nitrate tolerance of meal-induced insulin sensitization in conscious rabbits. Journal of cardiovascular pharmacology 20111101
Visfatin induces neurite outgrowth in PC12 cells via ERK1/2 signaling pathway. Neuroscience letters 20111024
Stimulative effects of Polygonum amplexicaule var. sinense on osteoblastic MC3T3-E1 cells. Pharmaceutical biology 20111001
Inhibition of Delta1 promotes differentiation of odontoblasts and inhibits proliferation of human dental pulp stem cell in vitro. Archives of oral biology 20110901
Acetyl-L-carnitine ameliorates spatial memory deficits induced by inhibition of phosphoinositol-3 kinase and protein kinase C. Journal of neurochemistry 20110901
[Effect of chai qin cheng qi decoction on serum CCK-8 and calcium overload of pancreatic acinar in mice with acute pancreatitis]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110901
Silencing of MGMT with small interference RNA reversed resistance in human BCUN-resistant glioma cell lines. Chinese medical journal 20110901
New anthranilic acid based antagonists with high affinity and selectivity for the human cholecystokinin receptor 1 (hCCK1-R). Journal of medicinal chemistry 20110825
Fluorescence polarization screening for allosteric small molecule ligands of the cholecystokinin receptor. Assay and drug development technologies 20110801
Cholecystokinin exerts an effect via the endocannabinoid system to inhibit GABAergic transmission in midbrain periaqueductal gray. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110801
Ternary complexes of amphiphilic polycaprolactone-graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery. Biomaterials 20110601
The short term satiety peptide cholecystokinin reduces meal size and prolongs intermeal interval. Peptides 20110601
A fundamental role for NO-PLC signaling pathway in mediating intracellular Ca2+ oscillation in pancreatic acini. Nitric oxide : biology and chemistry 20110430
Rosiglitazone promotes pancreatic regeneration in experimental model of acute pancreatitis. Fundamental & clinical pharmacology 20110401
Additive effects of cannabinoid CB1 receptors blockade and cholecystokinin on feeding inhibition. Pharmacology, biochemistry, and behavior 20110401
Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways: implications for leptin as a regulator of short term satiety. The Journal of biological chemistry 20110401
Biodegradable block poly(ester-urethane)s based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) copolymers. Biomaterials 20110401
[Effects of cholecystokinin octapeptide on the contractile activity of guinea-pig colonic smooth muscles, L-type calcium currents and membrane potentials of myocytes]. Zhonghua yi xue za zhi 20110329
Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity. Pharmacogenetics and genomics 20110301
[Oxidative damage to the endoplasmic reticulum stress pathway of apoptosis-related molecules expression in MIN6 cell]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110301
Ethanol impairs the assembly and disassembly of actin cytoskeleton and cell adhesion via the RhoA signaling pathway, catenin p120 and E-cadherin in CCK-stimulated pancreatic acini. Biochemical and biophysical research communications 20110225
Rapakinin, Arg-Ile-Tyr, derived from rapeseed napin, shows anti-opioid activity via the prostaglandin IP receptor followed by the cholecystokinin CCK(2) receptor in mice. Peptides 20110201
Sulfated cholecystokinin-8 activates phospho-mTOR immunoreactive neurons of the paraventricular nucleus in rats. Peptides 20110101
Berberine attenuates calyculin A-induced cytotoxicity and Tau hyperphosphorylation in HEK293 cells. Journal of Alzheimer's disease : JAD 20110101
Upregulation of AKT attenuates amyloid-β-induced cell apoptosis. Journal of Alzheimer's disease : JAD 20110101
Emodin potentiates the antitumor effects of gemcitabine in pancreatic cancer cells via inhibition of nuclear factor-κB. Molecular medicine reports 20110101
The improvement of fibroblast growth on hydrophobic biopolyesters by coating with polyhydroxyalkanoate granule binding protein PhaP fused with cell adhesion motif RGD. Biomaterials 20101201
Monoclonal antibody to the six-transmembrane epithelial antigen of prostate 4 promotes apoptosis and inhibits proliferation and glucose uptake in human adipocytes. International journal of molecular medicine 20101201
Response to: Laparoscopic cholecystectomy is safe and effective for the treatment of biliary dyskinesia in the pediatric population. The American surgeon 20101201
Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells. Neurochemistry international 20101101
The anorexigenic effect of cholecystokinin octapeptide in a goldfish model is mediated by the vagal afferent and subsequently through the melanocortin- and corticotropin-releasing hormone-signaling pathways. Peptides 20101101
Melatonin induces calcium release from CCK-8- and thapsigargin-sensitive cytosolic stores in pancreatic AR42J cells. Journal of pineal research 20101001
Anti-inflammatory action of cholecystokinin and melatonin in the rat parotid gland. Oral diseases 20101001
Effects of cholesterol on CCK-1 receptors and caveolin-3 proteins recycling in human gallbladder muscle. American journal of physiology. Gastrointestinal and liver physiology 20100901
Repeated administration of methamphetamine blocked cholecystokinin-octapeptide injection-induced c-fos mRNA expression without change in capsaicin-induced junD mRNA expression in rat cerebellum. Journal of neural transmission (Vienna, Austria : 1996) 20100901
Dorsal vagal preganglionic neurons: differential responses to CCK1 and 5-HT3 receptor stimulation. Autonomic neuroscience : basic & clinical 20100825
Immunosuppressive constituents from Urtica dentata Hand. Journal of Asian natural products research 20100801
Stress impairs GABAergic network function in the hippocampus by activating nongenomic glucocorticoid receptors and affecting the integrity of the parvalbumin-expressing neuronal network. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100701
Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. American journal of physiology. Gastrointestinal and liver physiology 20100701
Peripherally injected CCK-8S activates CART positive neurons of the paraventricular nucleus in rats. Peptides 20100601
Increased calcium influx in the presence of ethanol in mouse pancreatic acinar cells. International journal of experimental pathology 20100401
Cloning/characterization of the canine organic anion transporting polypeptide 1b4 (Oatp1b4) and classification of the canine OATP/SLCO members. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100401
Comparison between two kinds of cigarette smoke condensates (CSCs) of the cytogenotoxicity and protein expression in a human B-cell lymphoblastoid cell line using CCK-8 assay, comet assay and protein microarray. Mutation research 20100329
Mechanisms mediating CCK-8S-induced contraction of proximal colon in guinea pigs. World journal of gastroenterology 20100307
Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line. Pancreas 20100301
Progesterone receptor A mediates VIP inhibition of contraction. American journal of physiology. Gastrointestinal and liver physiology 20100301
Analysis of oxidation process of cholecystokinin octapeptide with reactive oxygen species by high-performance liquid chromatography and subsequent electrospray ionization mass spectrometry. Biomedical chromatography : BMC 20100201
Collagen II/hyaluronan/chondroitin-6-sulfate tri-copolymer scaffold for nucleus pulposus tissue engineering. Journal of biomedical materials research. Part B, Applied biomaterials 20100201
Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 β production in a cancer-induced pain model in mice. Molecular pain 20100101
Nesfatin-1 evokes Ca2+ signaling in isolated vagal afferent neurons via Ca2+ influx through N-type channels. Biochemical and biophysical research communications 20091218
Effects of exogenous annexin-1 on lipopolysaccharide-induced proliferation and reactive oxygen species production partially through modulation of CRAC channels but independent of NF-kappaB pathway. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20091201
L-DOPA-induced neurotoxicity is reduced by the activation of the PI3K signaling pathway. Toxicology 20091130
Hsp90 Co-localizes with Rab-GDI-1 and regulates agonist-induced amylase release in AR42J cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20091101
Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis. Gastroenterology 20091001
Inhibitory effects of somatostatin on cholecystokinin octapeptide induced bile regurgitation under stress: ionic and molecular mechanisms. Regulatory peptides 20090807
Possible mechanism of CCL2-induced Akt activation in prostate cancer cells. Anticancer research 20090801
Prosurvival Bcl-2 proteins stabilize pancreatic mitochondria and protect against necrosis in experimental pancreatitis. Experimental cell research 20090701
Alternative block polyurethanes based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) and poly(ethylene glycol). Biomaterials 20090601
A high-fat diet attenuates the central response to within-meal satiation signals and modifies the receptor expression of vagal afferents in mice. American journal of physiology. Regulatory, integrative and comparative physiology 20090601
Interventions used with cholescintigraphy for the diagnosis of hepatobiliary disease. Seminars in nuclear medicine 20090501
Valproate activates the Notch3/c-FLIP signaling cascade: a strategy to attenuate white matter hyperintensities in bipolar disorder in late life? Bipolar disorders 20090501
Effect of viscosity on appetite and gastro-intestinal hormones. Physiology & behavior 20090420
NMDA NR2 receptors participate in CCK-induced reduction of food intake and hindbrain neuronal activation. Brain research 20090417
Gastrointestinal growth factors and hormones have divergent effects on Akt activation. Cellular signalling 20090401
Phenotype of neurons in the nucleus of the solitary tract that express CCK-induced activation of the ERK signaling pathway. American journal of physiology. Regulatory, integrative and comparative physiology 20090401
Cholecystokinin-8 sulfate modulates the anticonvulsant efficacy of vigabatrin in an experimental model of partial complex epilepsy in the rat. Epilepsia 20090401
Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors. Brain : a journal of neurology 20090301
Neuroprotective effects of donepezil through inhibition of GSK-3 activity in amyloid-beta-induced neuronal cell death. Journal of neurochemistry 20090301
The roles of nerve growth factor and cholecystokinin in the enhancement of morphine analgesia in a rodent model of central nervous system inflammation. Neuropharmacology 20090301
Neuroprotection of interleukin-6 against NMDA attack and its signal transduction by JAK and MAPK. Neuroscience letters 20090130
CCK-8S inhibited the NMDA-activated current of cultured hippocampal neuron under normal and ethanol exposure conditions. Neuroscience letters 20090102
Ethanol exerts dual effects on calcium homeostasis in CCK-8-stimulated mouse pancreatic acinar cells. BMC cell biology 20090101
Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model. Drug metabolism and disposition: the biological fate of chemicals 20081201
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. Journal of medicinal chemistry 20081127
Ethanol impairs calcium homeostasis following CCK-8 stimulation in mouse pancreatic acinar cells. Alcohol (Fayetteville, N.Y.) 20081101
[Oxidative stress experimental model of rat with stria vascularis marginal cells injury induced by hydrogen peroxide in vitro]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20081101
Responses of human sling and clasp fibers to cholecystokinin (CCK) and gastrin through CCK receptors. Journal of gastroenterology and hepatology 20081001
Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. Journal of neurochemistry 20081001
Amino acid residues in transmembrane domain 10 of organic anion transporting polypeptide 1B3 are critical for cholecystokinin octapeptide transport. Biochemistry 20080902
Overexpression of progesterone receptor B increases sensitivity of human colon muscle cells to progesterone. American journal of physiology. Gastrointestinal and liver physiology 20080901
Effects of cholecystokinin-58 on type 1 cholecystokinin receptor function and regulation. American journal of physiology. Gastrointestinal and liver physiology 20080901
Micelles by self-assembling peptide-conjugate amphiphile: synthesis and structural characterization. Journal of peptide science : an official publication of the European Peptide Society 20080801
Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells. Gastroenterology 20080801
Localization of CCK-1R in the omasum and role of CCK in the regulation of omasal contractions in sheep. Domestic animal endocrinology 20080801
The micelle-associated 3D structures of Boc-Y(SO3)-Nle-G-W-Nle-D-2-phenylethylester (JMV-180) and CCK-8(s) share conformational elements of a calculated CCK1 receptor-bound model. Journal of medicinal chemistry 20080710
A cholecystokinin-1 receptor agonist (CCK-8) mediates increased permeability of brain barriers to leptin. British journal of pharmacology 20080701
Microscale characterization of the binding specificity and affinity of a monoclonal antisulfotyrosyl IgG antibody. Electrophoresis 20080601
Cholecystokinin-A receptors regulate photic input pathways to the circadian clock. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501
Tonic and phasic pyloric activity in response to CCK-octapeptide. Digestive diseases and sciences 20080401
Role of CCK and potential utility of CCK1 receptor antagonism in the treatment of pancreatitis induced by biliary tract obstruction. British journal of pharmacology 20080401
Cholecystokinin-58 is more potent in inhibiting food intake than cholecystokinin-8 in rats. Nutritional neuroscience 20080401
Decrease in intestinal endocrine cells in Balb/c mice with CT-26 carcinoma cells. Journal of veterinary science 20080301
Sphincter of Oddi dysfunction in hypercholesterolemic rabbits. European journal of gastroenterology & hepatology 20080301
Involvement of cholecystokinin receptor in the inhibition of gastrointestinal motility by oxytocin in ovariectomized rats. European journal of pharmacology 20080212
A high-fat diet raises fasting plasma CCK but does not affect upper gut motility, PYY, and ghrelin, or energy intake during CCK-8 infusion in lean men. American journal of physiology. Regulatory, integrative and comparative physiology 20080101
Synergistic effect of CART (cocaine- and amphetamine-regulated transcript) peptide and cholecystokinin on food intake regulation in lean mice. BMC neuroscience 20080101
Identification and species similarity of OATP transporters responsible for hepatic uptake of beta-lactam antibiotics. Drug metabolism and pharmacokinetics 20080101
Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor. Drug metabolism and disposition: the biological fate of chemicals 20071201
Role of the amygdaloid cholecystokinin (CCK)/gastrin-2 receptors and terminal networks in the modulation of anxiety in the rat. Effects of CCK-4 and CCK-8S on anxiety-like behaviour and [3H]GABA release. The European journal of neuroscience 20071201
Interaction of apolipoprotein AIV with cholecystokinin on the control of food intake. American journal of physiology. Regulatory, integrative and comparative physiology 20071001
Distribution of neuroendocrine cells in the small and large intestines of the one-humped camel (Camelus dromedarius). Neuropeptides 20071001
Zerumbone exerts a beneficial effect on inflammatory parameters of cholecystokinin octapeptide-induced experimental pancreatitis but fails to improve histology. Pancreas 20071001
Effects of potential mediators of an intestinal brake mechanism on gut motility in Chinook salmon (Oncorhynchus tshawytscha). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070901
Cholecystokinin B-type receptors mediate a G-protein-dependent depolarizing action of sulphated cholecystokinin ocatapeptide (CCK-8s) on rodent neonatal spinal ventral horn neurons. Journal of neurophysiology 20070901
Vagus nerve integrity and experimental colitis. American journal of physiology. Gastrointestinal and liver physiology 20070901
Modulation of CCK-8-evoked intracellular Ca2+ waves by hydrogen peroxide in mouse pancreatic acinar cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901
The effect of concomitant stimulation with cholecystokinin and epidermal growth factor on extracellular signal-regulated kinase (ERK) activity in pancreatic acinar cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901
Effects of long term hydrophilic bile acid therapy on in vitro contraction of gallbladder muscle strips in patients with cholesterol gallstones. World journal of gastroenterology 20070828
Vagally mediated, nonparacrine effects of cholecystokinin-8s on rat pancreatic exocrine secretion. American journal of physiology. Gastrointestinal and liver physiology 20070801
Cholecystokinin-8s excites identified rat pancreatic-projecting vagal motoneurons. American journal of physiology. Gastrointestinal and liver physiology 20070801
Cholecystokinin CCK2 receptors mediate the peptide's inhibitory actions on the contractile activity of human distal colon via the nitric oxide pathway. British journal of pharmacology 20070801
Pioglitazone reverses insulin resistance and impaired CCK-stimulated pancreatic secretion in eNOS(-/-) mice: therapy for exocrine pancreatic disorders? American journal of physiology. Gastrointestinal and liver physiology 20070701
Role of caveolae in the pathogenesis of cholesterol-induced gallbladder muscle hypomotility. American journal of physiology. Gastrointestinal and liver physiology 20070601
Local inhibitory reflexes excited by mucosal application of nutrient amino acids in guinea pig jejunum. American journal of physiology. Gastrointestinal and liver physiology 20070601
Secretagogues differentially activate endoplasmic reticulum stress responses in pancreatic acinar cells. American journal of physiology. Gastrointestinal and liver physiology 20070601
Unexpected relationship between plasma protein binding and the pharmacodynamics of 2-NAP, a CCK1-receptor antagonist. British journal of clinical pharmacology 20070501
Alcohol redirects CCK-mediated apical exocytosis to the acinar basolateral membrane in alcoholic pancreatitis. Traffic (Copenhagen, Denmark) 20070501
Selective cyclooxygenase-2 inhibitor ameliorates cholecystokinin-octapeptide-induced acute pancreatitis in rats. World journal of gastroenterology 20070428
Supramaximal CCK-58 does not induce pancreatitis in the rat: role of pancreatic water secretion. American journal of physiology. Gastrointestinal and liver physiology 20070401
Gastric vagal efferent inhibition evoked by intravenous CRF is unrelated to simultaneously recorded vagal afferent activity in urethane-anesthetized rats. Journal of neurophysiology 20070401
[The role of protein kinase C-mediated phosphorylation of type III inositol 1, 4, 5-triphosphate receptor in cholecystokinin octapeptide induced calcium mobilization in gastric antral smooth muscle cells]. Zhonghua yi xue za zhi 20070313
Immunohistochemical study on the neuroendocrine system of the digestive tract of turbot, Scophthalmus maximus (L.), infected by Enteromyxum scophthalmi (Myxozoa). Fish & shellfish immunology 20070301
Effects of cholecystokinin-8s in the nucleus tractus solitarius of vagally deafferented rats. American journal of physiology. Regulatory, integrative and comparative physiology 20070301
Microinjection of exogenous somatostatin in the dorsal vagal complex inhibits pancreatic secretion via somatostatin receptor-2 in rats. American journal of physiology. Gastrointestinal and liver physiology 20070301
Periaqueductal gray cholecystokinin infusions block morphine-induced disruption of maternal behavior. Peptides 20070301
CCK2 receptors mediate inhibitory effects of cholecystokinin on the motor activity of guinea-pig distal colon. European journal of pharmacology 20070227
High-relaxivity supramolecular aggregates containing peptides and Gd complexes as contrast agents in MRI. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070201
Cholecystokinin-8S-induced intracellular calcium signaling in acutely isolated periaqueductal gray neurons of the rat. Biological & pharmaceutical bulletin 20070201
Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers. Biopolymers 20070101
Gastrointestinal hormones cause rapid c-Met receptor down-regulation by a novel mechanism involving clathrin-mediated endocytosis and a lysosome-dependent mechanism. The Journal of biological chemistry 20061208
Functional analysis of mouse and monkey multidrug resistance-associated protein 2 (Mrp2). Drug metabolism and disposition: the biological fate of chemicals 20061201
The ghrelin pentapeptide inhibits the secretion of pancreatic juice in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201
Modulatory effect of CCK-8S on GABA-induced depolarization from rat dorsal root ganglion. Brain research 20061122
Mechanism of exocrine pancreatic insufficiency in streptozotocin-induced type 1 diabetes mellitus. Annals of the New York Academy of Sciences 20061101
Peripheral injection of CCK-8S induces Fos expression in the dorsomedial hypothalamic nucleus in rats. Brain research 20061030
Early caspase-3 activation independent of apoptosis is required for cellular function. Journal of cellular physiology 20061001
Very low levels of cholecystokinin octapeptide activate Na-pump in the cerebral cortex of CCK2 receptor-deficient mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20061001
The vagus nerve: a tonic inhibitory influence associated with inflammatory bowel disease in a murine model. Gastroenterology 20061001
[The effect and mechanism of cholecystokinin octapeptide induced-gastric dysmotility on bile regurgitation during stress]. Zhonghua nei ke za zhi 20061001
Cellular action of cholecystokinin-8S-mediated excitatory effects in the rat periaqueductal gray. Life sciences 20060927
Effect of cholecystokinin on feeding is attenuated in monosodium glutamate obese mice. Regulatory peptides 20060911
The antagonism of cholecystokinin octapeptide-8 to the peroxynitrite oxidation on a diabetic cataractal rat model. Chinese medical journal 20060905
Ethanol sensitizes NF-kappaB activation in pancreatic acinar cells through effects on protein kinase C-epsilon. American journal of physiology. Gastrointestinal and liver physiology 20060901
Determination of the biliary excretion of piperacillin in humans using a novel method. British journal of clinical pharmacology 20060901
Enzymatic properties of human aminopeptidase A. Regulation of its enzymatic activity by calcium and angiotensin IV. The Journal of biological chemistry 20060818
Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans. Drug metabolism and disposition: the biological fate of chemicals 20060701
Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans. Drug metabolism and disposition: the biological fate of chemicals 20060701
Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors. Journal of medicinal chemistry 20060518
Cholecystokinin- and gastrin-induced protein and amylase secretion from the parotid gland of the anaesthetized rat. Regulatory peptides 20060515
Effect of sympathectomy and demedullation on increased myenteric and dorsal vagal complex Fos-like immunoreactivity by cholecystokinin-8. Regulatory peptides 20060515
Molecular characterization and inhibition of amanitin uptake into human hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology 20060501
Involvement of cholecystokinin in peripheral nociceptive sensitization during diabetes in rats as revealed by the formalin response. Pain 20060501
[Effects and mechanisms of cholecystokinin octapeptide on hippocampal injury during endotoxic shock]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060501
Anthranilic acid based CCK1 receptor antagonists and CCK-8 have a common step in their 'receptor desmodynamic processes'. Journal of medicinal chemistry 20060420
Comparison of protocatechuic aldchyde in Radix Salvia miltiorrhiza and corresponding pharmacological sera from normal and fibrotic rats by high performance liquid chromatography. World journal of gastroenterology 20060414
Cytotoxic and antimitotic effects of N-containing Monascus metabolites studied using immortalized human kidney epithelial cells. Molecular nutrition & food research 20060401
[Receptor mechanisms underlying the modulation of lipopolysaccharide-induced nuclear factor-kappaB expression in vascular endothelial cells by cholecystokinin octapeptide]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20060301
Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. Journal of natural products 20060301
Beneficial effect of resveratrol on cholecystokinin-induced experimental pancreatitis. European journal of pharmacology 20060217
Estrogen and CCK1 receptor modification of mu-opioid receptor binding in the cortex of female rats. Brain research 20060216
Adapter protein CRKII signaling is involved in the rat pancreatic acini response to reactive oxygen species. Journal of cellular biochemistry 20060201
Dose-dependent effect of hydrogen peroxide on calcium mobilization in mouse pancreatic acinar cells. Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201
Cholecystokinin-2 receptors couple to cAMP-protein kinase A to depress excitatory synaptic currents in rat nucleus accumbens in vitro. Canadian journal of physiology and pharmacology 20060201
Effect of intraperitoneal CCK-8 on food intake and brain orexin-A after 48 h of fasting in the rat. Regulatory peptides 20060115
Blockade of central GLP-1 receptors prevents CART-induced hypophagia and brain c-Fos expression. Peptides 20060101
A novel, quantitative bio-assay for cholecystokinin type-1 receptor activity in the anaesthetised rat. Journal of pharmacological and toxicological methods 20060101
Ethanol impairs CCK-8-evoked amylase secretion through Ca2+-mediated ROS generation in mouse pancreatic acinar cells. Alcohol (Fayetteville, N.Y.) 20060101
Signal transduction pathways mediating CCK-8S-induced gastric antral smooth muscle contraction. Digestion 20060101
Effect of cholecystokinin octapeptide on diacylglycerol-PKC signaling pathway in rat pulmonary interstitial macrophages stimulated by lipopolysaccharide. Acta pharmacologica Sinica 20051201
Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors. Journal of medicinal chemistry 20051117
C-type natriuretic peptide applied to the brain enhances exocrine pancreatic secretion through a vagal pathway. European journal of pharmacology 20051107
The proteasome inhibitor MG132 protects against acute pancreatitis. Free radical biology & medicine 20051101
Strain differences in myenteric neuron number and CCK1 receptor mRNA expression may account for differences in CCK induced c-Fos activation. Brain research 20051005
Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans. Drug metabolism and disposition: the biological fate of chemicals 20051001
Human hepatobiliary transport of organic anions analyzed by quadruple-transfected cells. Molecular pharmacology 20051001
Cholecystokinin octapeptide increases spontaneous glutamatergic synaptic transmission to neurons of the nucleus tractus solitarius centralis. Journal of neurophysiology 20051001
Selective CCK-A but not CCK-B receptor antagonists inhibit HT-29 cell proliferation: synergism with pharmacological levels of melatonin. Journal of pineal research 20051001
Overeating after restraint stress in cholecystokinin-a receptor-deficient mice. The Japanese journal of physiology 20051001
Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity. American journal of physiology. Regulatory, integrative and comparative physiology 20050901
Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050810
Inhibitory effects on intake of cholecystokinin-8 and cholecystokinin-33 in rats with hepatic proper or common hepatic branch vagal innervation. American journal of physiology. Regulatory, integrative and comparative physiology 20050801
Effects of cholecystokinin-receptor antagonists on Fos-like immunoreactivity stimulated by sulfated cholecystokinin-8 in neurons of the myenteric plexus and hindbrain of rats. American journal of veterinary research 20050801
[The responses of pain-related neurons in habenula to nociceptive stimuli and morphine]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050801
Changes in the satiating effect of cholecystokinin over repeated trials. Physiology & behavior 20050721
Epileptogenesis and chronic seizures in a mouse model of temporal lobe epilepsy are associated with distinct EEG patterns and selective neurochemical alterations in the contralateral hippocampus. Experimental neurology 20050701
Cholecystokinin octapeptide improves cardiac function by activating cholecystokinin octapeptide receptor in endotoxic shock rats. World journal of gastroenterology 20050614
Intake inhibition by NPY and CCK-8: A challenge of the notion of NPY as an 'Orexigen'. Behavioural brain research 20050603
Effect of protein kinase C on proliferation and apoptosis of T lymphocytes in idiopathic thrombocytopenic purpura children. Cellular & molecular immunology 20050601
Satiety enhancement by selective orexin-1 receptor antagonist SB-334867: influence of test context and profile comparison with CCK-8S. Behavioural brain research 20050507
Water and enzyme secretion are tightly coupled in pancreatic secretion stimulated by food or CCK-58 but not by CCK-8. American journal of physiology. Gastrointestinal and liver physiology 20050501
Vectorial transport of the peptide CCK-8 by double-transfected MDCKII cells stably expressing the organic anion transporter OATP1B3 (OATP8) and the export pump ABCC2. The Journal of pharmacology and experimental therapeutics 20050501
Inhibitor-based validation of a homology model of the active-site of tripeptidyl peptidase II. Journal of molecular graphics & modelling 20050401
CCK-8 prevents the development of kindling and regulates the GABA and NPY expression in the hippocampus of pentylenetetrazole (PTZ)-treated adult rats. Neuropharmacology 20050401
Changes of the gastric endocrine cells in the C57BL/6 mouse after implantation of murine lung carcinoma: an immunohistochemical quantitative study. World journal of gastroenterology 20050307
Effect of CCK-8 on insulin-induced hyperphagia and hypothalamic orexigenic neuropeptide expression in the rat. Peptides 20050301
Electrophysiological responses of nucleus tractus solitarius neurons to CCK and gastric distension in newborn lambs. Cellular and molecular neurobiology 20050301
A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis. World journal of gastroenterology 20050221
Cleavage of SNAP-25 and VAMP-2 impairs store-operated Ca2+ entry in mouse pancreatic acinar cells. American journal of physiology. Cell physiology 20050101
Failure of cholecystokinin-octapeptide to prevent TPN-associated gallstone disease. Journal of pediatric surgery 20050101
Synthesis and evaluation of N-(5-methyl-3-oxo-1,2- diphenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-phenylureas as cholecystokinin antagonists. Arzneimittel-Forschung 20050101
Redistribution of CB1 cannabinoid receptors during evolution of cholinergic basal forebrain territories and their cortical projection areas: a comparison between the gray mouse lemur (Microcebus murinus, primates) and rat. Neuroscience 20050101
Pharmacological characterization of rebamipide: its cholecystokinin CCK1 receptor binding profile and effects on Ca2+ mobilization and amylase release in rat pancreatic acinar cells. European journal of pharmacology 20041128
Cholecystokinin octapeptide: a potential growth factor for pancreatic beta cells in diabetic rats. JOP : Journal of the pancreas 20041110
Systemic and intra-dorsal periaqueductal gray injections of cholecystokinin sulfated octapeptide (CCK-8s) induce a panic-like response in rats submitted to the elevated T-maze. Peptides 20041101
Changes in IP3 receptor are associated with altered calcium response to cholecystokinin in diabetic rat pancreatic acini. Pancreas 20041101
A role for dopamine in feeding responses produced by orexigenic agents. Brain research 20041015
5-(tryptophylamino)-1,3-dioxoperhydropyrido[1,2-c]pyrimidine-based cholecystokinin receptor antagonists: reversal of CCK1 receptor subtype selectivity toward CCK2 receptors. Journal of medicinal chemistry 20041007
Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. The Journal of pharmacology and experimental therapeutics 20041001
Effect of lipopolysaccharide on expression and characterization of cholecystokinin receptors in rat pulmonary interstitial macrophages. Acta pharmacologica Sinica 20041001
Cholecystokinin-8-induced hypoplasia of the rat pancreas: influence of nitric oxide on cell proliferation and programmed cell death. Basic & clinical pharmacology & toxicology 20041001
Suppression of food intake by GI fatty acid infusions: roles of celiac vagal afferents and cholecystokinin. Physiology & behavior 20040801
Interaction of TRH and CCK in the satiation of alcohol intake. Physiology & behavior 20040801
Studying ingestive behavior with Gerry Smith. Physiology & behavior 20040801
Insulin is necessary for the hypertrophic effect of cholecystokinin-octapeptide following acute necrotizing experimental pancreatitis. World journal of gastroenterology 20040801
Total enzymatic synthesis of cholecystokinin CCK-5. Amino acids 20040801
ATP and ATPase secretion by exocrine pancreas in rat, guinea pig, and human. Pancreas 20040701
Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells: comparison of different modes of evaluating DeltaPsim. The Journal of biological chemistry 20040625
Heme oxygenase-1 in cholecystokinin-octapeptipe attenuated injury of pulmonary artery smooth muscle cells induced by lipopolysaccharide and its signal transduction mechanism. World journal of gastroenterology 20040615
Abdominal vagal mediation of the satiety effects of CCK in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20040601
Dietary virgin olive oil enhances secretagogue-evoked calcium signaling in rat pancreatic acinar cells. Nutrition (Burbank, Los Angeles County, Calif.) 20040601
CCK-8 and PGE1: central effects on circadian body temperature and activity rhythms in rats. Physiology & behavior 20040601
Pancreatic exocrine secretion and plasma concentration of some gastrointestinal hormones in response to abomasal infusion of starch hydrolyzate and/or casein. Journal of animal science 20040601
NMDA receptor blockade attenuates CCK-induced reduction of real feeding but not sham feeding. American journal of physiology. Regulatory, integrative and comparative physiology 20040501
Physicochemical properties of mixed micellar aggregates containing CCK peptides and Gd complexes designed as tumor specific contrast agents in MRI. Journal of the American Chemical Society 20040317
Secretagogue-stimulated pancreatic secretion is differentially regulated by constitutive NOS isoforms in mice. American journal of physiology. Gastrointestinal and liver physiology 20040301
In vitro and in vivo evaluation of 111In-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040301
Cholecystokinin octapeptide inhibits carotid sinus baroreflex in anesthetized rats. Sheng li xue bao : [Acta physiologica Sinica] 20040225
Cholecystokinin octapeptide increases free intracellular calcium of guinea pig cardiomyocytes through activation of Ca2+ channel and tyrosine kinase. Sheng li xue bao : [Acta physiologica Sinica] 20040225
Cholecystokinin activates CCKB receptors to excite cells and depress EPSCs in the rat rostral nucleus accumbens in vitro. The Journal of physiology 20040215
Structure-activity function for binding and signaling in CHO-K1 and COS-7 cells expressing the cholecystokinin A receptor. Biochemical and biophysical research communications 20040213
Coordinated gastric and sphincter motility evoked by intravenous CCK-8 as monitored by ultrasonomicrometry in rats. American journal of physiology. Gastrointestinal and liver physiology 20040201
Phosphatidylinositide 3-kinase gamma regulates key pathologic responses to cholecystokinin in pancreatic acinar cells. Gastroenterology 20040201
In vitro and in vivo characterization of Indium-111 and Technetium-99m labeled CCK-8 derivatives for CCK-B receptor imaging. Cancer biotherapy & radiopharmaceuticals 20040201
Synthesis and biological characterisation of [3H]BBL454, a new CCK2 selective radiolabelled agonist displaying original pharmacological properties. Bioorganic & medicinal chemistry letters 20040119
Single-unit activity of paraventricular nucleus neurons in response to intero- and exteroceptive stressors in conscious, freely moving rats. Brain research 20040102
Role of PGE2 on gallbladder muscle cytoprotection of guinea pigs. American journal of physiology. Gastrointestinal and liver physiology 20040101
Anxiogenic effect of cholecystokinin in the dorsal periaqueductal gray. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040101
Jejunal administration of linoleic acid increases activity of neurons in the paraventricular nucleus of the hypothalamus. American journal of physiology. Regulatory, integrative and comparative physiology 20040101
Inhibitory effect of the lectin wheat germ agglutinin on the binding of 125I-CCK-8s to the CCK-A and -B receptors of AR42J cells. Pancreas 20040101
Ethanol modifies the actin cytoskeleton in rat pancreatic acinar cells--comparison with effects of CCK. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20040101
Altered action of dopamine and cholecystokinin on lateral hypothalamic neurons in rats raised under different feeding conditions. Behavioural brain research 20031217
Oxytocin innervation of caudal brainstem nuclei activated by cholecystokinin. Brain research 20031212
Cholecystokinin activates both A- and C-type vagal afferent neurons. American journal of physiology. Gastrointestinal and liver physiology 20031201
Cholecystokinin rapidly stimulates CrkII function in vivo in rat pancreatic acini. Formation of CrkII-protein complexes. European journal of biochemistry 20031201
[Altered cholecystokinin-induced calcium signal in streptozotocin-induced diabetic rat pancreatic acini]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20031201
Changes in mitochondrial activity evoked by cholecystokinin in isolated mouse pancreatic acinar cells. Cellular signalling 20031101
Animal and in vitro models of alcoholic pancreatitis: role of cholecystokinin. Pancreas 20031101
Differential mechanism and site of action of CCK on the pancreatic secretion and growth in rats. American journal of physiology. Gastrointestinal and liver physiology 20031001
Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031001
Complementary distribution of type 1 cannabinoid receptors and vesicular glutamate transporter 3 in basal forebrain suggests input-specific retrograde signalling by cholinergic neurons. The European journal of neuroscience 20031001
Lack of cholecystokinin-A receptor enhanced gallstone formation: a study in CCK-A receptor gene knockout mice. Digestive diseases and sciences 20031001
Cholecystokinin-stimulated protein kinase C-delta kinase activation, tyrosine phosphorylation, and translocation are mediated by Src tyrosine kinases in pancreatic acinar cells. The Journal of biological chemistry 20030912
CCK-58 is the only detectable endocrine form of cholecystokinin in rat. American journal of physiology. Gastrointestinal and liver physiology 20030801
Effects of peripheral CCK receptor blockade on food intake in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20030801
Differential startle reactivity following central CCK-8S and systemic Boc CCK-4 administration in mice: antecedent stressor history and testing condition. Behavioral neuroscience 20030801
CCK-nitric oxide interaction in rat cortex, striatum and pallidum. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030801
Modulation of meal pattern in the rat by the anorexic lipid mediator oleoylethanolamide. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701
Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin. The Journal of pharmacy and pharmacology 20030701
Exogenous leptin inhibits the secretion of pancreatic juice via a duodenal CCK1-vagal-dependent mechanism in anaesthetized rats. Regulatory peptides 20030615
Molecular cloning of an unusual bicistronic cholecystokinin receptor mRNA expressed in chicken brain: a structural and functional expression study. Regulatory peptides 20030615
Melatonin-induced calcium signaling in clusters of human and rat duodenal enterocytes. American journal of physiology. Gastrointestinal and liver physiology 20030601
Hydrophilic but not hydrophobic bile acids prevent gallbladder muscle dysfunction in acute cholecystitis. Hepatology (Baltimore, Md.) 20030601
Phosphospecific site tyrosine phosphorylation of p125FAK and proline-rich kinase 2 is differentially regulated by cholecystokinin receptor type A activation in pancreatic acini. The Journal of biological chemistry 20030523
Oxygen radical production precedes alcohol-induced acute pancreatitis in rats. Pancreas 20030501
Central D-Ala2-Met5-enkephalinamide mu/delta-opioid receptor activation reverses the anxiogenic-like properties of cholecystokinin on locomotor and rearing activity in CD-1 mice. Brain research 20030425
Central D-Ala2-Met5-enkephalinamide mu/delta-opioid receptor activation blocks behavioral sensitization to cholecystokinin in CD-1 mice. Brain research 20030425
[Effects of cholecystokinin-octapeptide on the tension of pulmonary artery in rabbits with endotoxic shock]. Sheng li xue bao : [Acta physiologica Sinica] 20030425
Effects of bioactive agents on biliary motor function. Current gastroenterology reports 20030401
Further evidence that the CCK2 receptor is coupled to two transduction pathways using site-directed mutagenesis. Journal of neurochemistry 20030401
CCK-8 modulates GABA-stimulated [3H]-flunitrazepam binding in vitro. Methods and findings in experimental and clinical pharmacology 20030401
Conserved cholecystokinin receptor transmembrane domain IV amino acids confer peptide affinity. Journal of molecular neuroscience : MN 20030401
The anti-inflammatory effect of methylprednisolone occurs down-stream of nuclear factor-kappaB DNA binding in acute pancreatitis. European journal of pharmacology 20030319
Role for the cholecystokinin-A receptor in fever: a study of a mutant rat strain and a pharmacological analysis. The Journal of physiology 20030315
An immunohistochemical study on the neuropeptide-producing endocrine cells in the alimentary tract of wrinkled frog, Rana rugosa (Ranidae). General and comparative endocrinology 20030301
Cholecystokinin induces cerebral vasodilatation via presynaptic CCK2 receptors: new implications for the pathophysiology of panic. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030301
Endogenous CCK depresses contractile activity within the ascending myenteric reflex pathway of rat ileum. Neuropharmacology 20030301
Effects of peripheral CCK receptor blockade on feeding responses to duodenal nutrient infusions in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20030201
Curcumin ameliorates ethanol and nonethanol experimental pancreatitis. American journal of physiology. Gastrointestinal and liver physiology 20030101
Central cholecystokinin-octapeptide accelerates the activity of the hypothalamic gonadotropin-releasing hormone pulse generator in goats. Journal of neuroendocrinology 20030101
Transient agonist-induced regulation of the cholecystokinin-A and cholecystokinin-B receptor mRNA levels in rat pancreatic acinar AR42J cells. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20030101
A secretin i.v. infusion activates gene expression in the central amygdala of rats. Neuroscience 20030101
Inhibitory effects of human and porcine alpha-amylase on CCK-8-stimulated lipase secretion of isolated rat pancreatic acini. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20030101
[Effect of conjunctive instillation of cholecystokinin 26-33 on pancreatic endocrine function in type 1 diabetes mellitus]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101
The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop? Regulatory peptides 20021231
Cholecystokinin increases cytosolic calcium in a subpopulation of cultured vagal afferent neurons. American journal of physiology. Regulatory, integrative and comparative physiology 20021201
General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals. Anesthesiology 20021201
Comparison of fatty meal and intravenous cholecystokinin infusion for gallbladder ejection fraction. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20021201
Human pancreatic acinar cells do not respond to cholecystokinin. Pharmacology & toxicology 20021201
Where have all the Na+ channels gone? In search of functional ENaC in exocrine pancreas. Biochimica et biophysica acta 20021113
Tripeptidyl peptidase-I is essential for the degradation of sulphated cholecystokinin-8 (CCK-8S) by mouse brain lysosomes. Neuroscience letters 20021011
Aging and panicogenic response to cholecystokinin tetrapeptide: an examination of the cholecystokinin system. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021001
Lysosomal degradation of cholecystokinin-(29-33)-amide in mouse brain is dependent on tripeptidyl peptidase-I: implications for the degradation and storage of peptides in classical late-infantile neuronal ceroid lipofuscinosis. The Biochemical journal 20020901
Antinociceptive mechanisms of platycodin D administered intracerebroventricularly in the mouse. Planta medica 20020901
Regional distribution and relative frequency of gastrointestinal endocrine cells in large intestines of C57BL/6 mice. Journal of veterinary science 20020901
Effect of cholecystokinin octapeptide on tumor necrosis factor alpha transcription and nuclear factor-kappaB activity induced by lipopolysaccharide in rat pulmonary interstitial macrophages. World journal of gastroenterology 20020815
Amylase secretion from dispersed human pancreatic acini: neither cholecystokinin a nor cholecystokinin B receptors mediate amylase secretion in vitro. Pancreas 20020801
Nitric oxide regulates the release of somatostatin from cultured gastric rabbit primary D-cells. Gastroenterology 20020801
Effects of cholecystokinin octapeptide on the exocrine pancreas in a new rat model of type 2 diabetes. European journal of pharmacology 20020719
Role of cholecystokinin-8 in nerve growth factor and nerve growth factor mRNA expression in carrageenan-induced joint inflammation in adult rats. Rheumatology (Oxford, England) 20020701
L-365,260 reversed effect of sincalide against morphine on electrical and mechanical activities of rat duodenum in vitro. Acta pharmacologica Sinica 20020701
Dibutyltin dichloride modifies amylase release from isolated rat pancreatic acini. Pancreas 20020701
Effects of cholecystokinin octapeptide on rat cardiac function and the receptor mechanism. Sheng li xue bao : [Acta physiologica Sinica] 20020625
Characteristics and mechanism of enzyme secretion and increase in [Ca2+]i in Saikosaponin(I) stimulated rat pancreatic acinar cells. World journal of gastroenterology 20020615
Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats. Free radical biology & medicine 20020615
The effect of phosphodiesterase inhibition on gallbladder motility in vitro. The Journal of surgical research 20020615
Effects of reactive oxygen species on actin filament polymerisation and amylase secretion in mouse pancreatic acinar cells. Cellular signalling 20020601
Characterization of CCK(A) receptor affinity states and Ca(2+) signal transduction in vagal nodose ganglia. American journal of physiology. Gastrointestinal and liver physiology 20020601
Low-affinity CCK-1 receptors inhibit bombesin-stimulated secretion in rat pancreatic acini--implication of the actin cytoskeleton. Regulatory peptides 20020515
Increased expression of gallbladder cholecystokinin: a receptor in prairie dogs fed a high-cholesterol diet and its dissociation with decreased contractility in response to cholecystokinin. The Journal of laboratory and clinical medicine 20020501
Pharmacological characterization of cholecystokinin receptors mediating contraction of human gallbladder and ascending colon. Regulatory peptides 20020415
Intestinal metabolism and absorption of cholecystokinin analogs in rats. Biochemical and biophysical research communications 20020405
Role of CCK-A receptor for pancreatic function in mice: a study in CCK-A receptor knockout mice. Pancreas 20020401
Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengers. The EMBO journal 20020301
XOD-catalyzed ROS generation mobilizes calcium from intracellular stores in mouse pancreatic acinar cells. Cellular signalling 20020201
Effect of CCK and intracellular calcium to regulate eIF2B and protein synthesis in rat pancreatic acinar cells. American journal of physiology. Gastrointestinal and liver physiology 20020201
Reactive oxygen species (H(2)O(2)): effects on the gallbladder muscle of guinea pigs. American journal of physiology. Gastrointestinal and liver physiology 20020201
Parenteral nutrition-associated liver complications in children. Pharmacotherapy 20020201
Principles of rat subcortical forebrain organization: a study using histological techniques and multiple fluorescence labeling. Journal of chemical neuroanatomy 20020201
A biochemical approach to study sub-second endogenous release of diverse neurotransmitters from central nerve terminals. Journal of neuroscience methods 20020115
Catecholaminergic innervation of the sympathetic preganglionic cell column of the filefish Stephanolepis cirrhifer. The Journal of comparative neurology 20020114
Mechanisms of gastric mucus secretion from cultured rat gastric epithelial cells induced by carbachol, cholecystokinin octapeptide, secretin, and prostaglandin E2. Biological & pharmaceutical bulletin 20020101
Comparison of effects of cholecystokinin and erythromycin on bile chemistry and gallstone formation in aged guinea pigs. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20020101
Comparative effects of water immersion pretreatment on three different acute pancreatitis models in rats. Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101
Pharmacologic interventions in nuclear radiology: indications, imaging protocols, and clinical results. Radiographics : a review publication of the Radiological Society of North America, Inc 20020101
Active relaxation of human gallbladder muscle is mediated by ATP-sensitive potassium channels. Digestion 20020101
Cholecystokinin-like immunoreactive amacrine cells in the rat retina. Visual neuroscience 20020101
[The effects of cholecystokinin octapeptide on PKC activity in rat cerebral cortex neurocytes]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20020101
Radiolabeling approaches for cholecystokinin B receptor imaging. Biopolymers 20020101
Effect of xanthine oxidase-catalyzed reactive oxygen species generation on secretagogue-evoked calcium mobilization in mouse pancreatic acinar cells. Biochemical pharmacology 20011215
Endogenous neurotensin facilitates enterohepatic bile acid circulation by enhancing intestinal uptake in rats. American journal of physiology. Gastrointestinal and liver physiology 20011201
Human pancreatic acinar cells lack functional responses to cholecystokinin and gastrin. Gastroenterology 20011201
Effect of exogenous cholecystokinin (CCK)-8 on food intake and plasma CCK, leptin, and insulin concentrations in older and young adults: evidence for increased CCK activity as a cause of the anorexia of aging. The Journal of clinical endocrinology and metabolism 20011201
Brain-gut axis in gastroprotection by leptin and cholecystokinin against ischemia-reperfusion induced gastric lesions. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20011201
[Role of nitric oxide in cholecystokinin octapeptide alleviation of tumor necrosis factor alpha induced changes in rabbit pulmonary arterial reactivity]. Sheng li xue bao : [Acta physiologica Sinica] 20011201
5-(Tryptophyl)amino-1,3-dioxoperhydropyrido[1,2-c]pyrimidine-based potent and selective CCK(1) receptor antagonists: structure-activity relationship studies on the central 1,3-dioxoperhydropyrido[1,2-c]pyrimidine scaffold. Journal of medicinal chemistry 20011122
Deficits in E2-dependent control of feeding, weight gain, and cholecystokinin satiation in ER-alpha null mice. Endocrinology 20011101
Effects of lectins on CCK-8-stimulated enzyme secretion and differentiation of the rat pancreatic cell line AR42J. Pancreas 20011101
Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver. Gastroenterology 20011101
Protein kinase C and calcium regulation of adenylyl cyclase in isolated rat pancreatic islets. Diabetes 20011101
The CCK-2 receptor is located on the ECL cell, but not on the parietal cell. Scandinavian journal of gastroenterology 20011101
Cholecystokinin fails to promote pancreatic regeneration in diabetic rats following the induction of experimental pancreatitis. Pharmacological research 20011101
Pyloric relaxation regulated via intramural neural pathway of the antrum. Digestive diseases and sciences 20011101
Jejunal or portal vein infusions of lipids increase hepatic vagal afferent activity. Neuroreport 20011008
Pancreatic acinar cell dysfunction in CFTR(-/-) mice is associated with impairments in luminal pH and endocytosis. Gastroenterology 20011001
Effect of exogenous cholecystokinin and secretin on pancreatic secretion of insulin and glucagon in rats: in vivo model without hepatic filter. Digestive diseases and sciences 20011001
Immunocytochemical and ultrastructural characterization of endocrine cells in the larval stomach of the frog Rana temporaria tadpoles: a comparison with adult specimens. Tissue & cell 20011001
Identification of CCK-B/gastrin receptor splice variants in human peripheral blood mononuclear cells. Regulatory peptides 20010915
Potentiation of NMDA receptor function through somatostatin release: a possible mechanism for the cognition-enhancing activity of GABA(B) receptor antagonists. Neuropharmacology 20010901
Rat pancreatic acinar cells express a cytosolic phospholipase D1b isoform that is not regulated by cholecystokinin. Pflugers Archiv : European journal of physiology 20010901
Abnormalities of gallbladder muscle associated with acute inflammation in guinea pigs. American journal of physiology. Gastrointestinal and liver physiology 20010801
PYY inhibits CCK-stimulated pancreatic secretion through the area postrema in unanesthetized rats. American journal of physiology. Regulatory, integrative and comparative physiology 20010801
Cholecystokinin/dopamine/GABA interactions in the nucleus accumbens: biochemical and functional correlates. Peptides 20010801
Cholecystokinin-8 (CCK-8) has no effect on heart rate in rats lacking CCK-A receptors. Peptides 20010801
Cholecystokinin modulation of apomorphine- or amphetamine-induced stereotypy in rats: opposite effects. Peptides 20010801
Stimulation of either cholecystokinin receptor subtype reduces while antagonists potentiate or sensitize a morphine-induced excitatory response. Peptides 20010801
Effects of forebrain microinjection of cholecystokinin on dopamine cell firing rate. Peptides 20010701
Effect of somatostatin on cholecystokinin-induced amylase release in rat pancreatic acini. Pancreas 20010701
The method of administration of cholecystokinin determines the effects evoked in the pancreas. Pancreas 20010701
Synthesis and solution characterization of a porphyrin-CCK8 conjugate. Journal of peptide science : an official publication of the European Peptide Society 20010701
Involvement of cellular calcium in exocrine pancreatic insufficiency during streptozotocin-induced diabetes mellitus. Archives of physiology and biochemistry 20010701
The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. European journal of pharmacology 20010629
The H3 receptor is involved in cholecystokinin inhibition of food intake in rats. Life sciences 20010615
Cholecystokinin-8 promotes recovery of sympathectomy induced by 6-hydroxydopamine in adult mice. Neuroreport 20010613
Contraction of human colonic circular smooth muscle cells is inhibited by the calcium channel blocker pinaverium bromide. Cell calcium 20010601
Vanadate inhibits the calcium extrusion in rat pancreatic acinar cells. Cellular signalling 20010601
Direct inhibitory effect of adrenomedullin, calcitonin gene-related peptide, calcitonin, and amylin on cholecystokinin-induced contraction of guinea-pig isolated caecal circular smooth muscle cells. Peptides 20010601
Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action. Biochemistry 20010515
Interaction of serotonin and cholecystokinin in the lateral parabrachial nucleus to control sodium intake. American journal of physiology. Regulatory, integrative and comparative physiology 20010501
Function and regulation of cholecystokinin octapeptide, beta-endorphin and gastrin in anorexic infantile rats treated with ErBao Granules. World journal of gastroenterology 20010415
Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin A receptor. Biochemistry 20010403
Cholecystokinin octapeptide induces both proliferation and apoptosis in the rat pancreas. Regulatory peptides 20010402
Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage. Neuroscience research 20010401
Enhanced intestinal motor response to cholecystokinin in post-Nippostrongylus brasiliensis-infected rats: modulation by CCK receptors and the vagus nerve. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20010401
Effect of leptin on insulin, glugacon and somatostatin secretion in the perfused rat pancreas. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010401
Role of cholecystokinin in the reduction of endomorphin-2-induced antinociception in diabetic mice. European journal of pharmacology 20010323
Design of non-peptide CCK2 and NK1 peptidomimetics using 1-(2-nitrophenyl)thiosemicarbazide as a novel common scaffold. Bioorganic & medicinal chemistry letters 20010312
Functional expression of cholecystokinin-A receptor on ventromedial hypothalamic neurons in the immature rat brain. Neuroscience letters 20010309
Sequential activation of heterotrimeric and monomeric G proteins mediates PLD activity in smooth muscle. American journal of physiology. Gastrointestinal and liver physiology 20010301
Comparative effects of amylin and cholecystokinin on food intake and gastric emptying in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20010301
Vacuolating toxin of Helicobacter pylori inhibits secretagogue-induced amylase secretion from isolated pancreatic acini. Pancreas 20010301
Impaired pancreatic secretion in severely malnourished patients is a consequence of primary pancreatic dysfunction. Nutrition (Burbank, Los Angeles County, Calif.) 20010301
Mecamylamine, a nicotinic receptor channel antagonist, affects amylase secretion by isolated pancreatic acinar cells. Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians 20010301
Role of leptin in ulcer healing. European journal of pharmacology 20010223
Gallbladder muscle dysfunction in patients with chronic acalculous disease. Gastroenterology 20010201
Effect of cholecystokinin-8 microinjection into ventral tegmental area on dopamine release in nucleus accumbens of rats: an in vivo voltammetric study. Progress in neuro-psychopharmacology & biological psychiatry 20010201
Release of calcium from mitochondrial and nonmitochondrial intracellular stores in mouse pancreatic acinar cells by hydrogen peroxide. The Journal of membrane biology 20010101
A possible interaction between CCKergic and GABAergic systems in the rat brain. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010101
Role of leptin in the stomach and the pancreas. Journal of physiology, Paris 20010101
Effects of putative galanin antagonists M35 and C7 on rat exocrine pancreas. Journal of physiology, Paris 20010101
Different affinity states of CCK(1) receptors on pancreatic acini and gastric smooth muscle in the rat. Journal of physiology, Paris 20010101
6-Hydroxydopamine infusions into the structures of mesolimbic dopaminergic system alter the memory enhancing effect of CK-8US and caerulein in rats. Folia histochemica et cytobiologica 20010101
Action of CCK and 5-HT on lateral hypothalamic neurons depends on early postnatal nutrition. Nutritional neuroscience 20010101
Estradiol has a direct impact on the exocrine pancreas as demonstrated by enzyme and vigilin expression. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20010101
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. Journal of medicinal chemistry 20000224
Cholecystokinin-8 enhances nerve growth factor synthesis and promotes recovery of capsaicin-induced sensory deficit. British journal of pharmacology 20000201
Acceleration of ulcer healing by cholecystokinin (CCK): role of CCK-A receptors, somatostatin, nitric oxide and sensory nerves. Regulatory peptides 19990630
Leptin in gastroprotection induced by cholecystokinin or by a meal. Role of vagal and sensory nerves and nitric oxide. European journal of pharmacology 19990618
SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. I. In vitro studies. The Journal of pharmacology and experimental therapeutics 19990501
Characterization of the binding of a novel radioligand to CCKB/gastrin receptors in membranes from rat cerebral cortex. British journal of pharmacology 19990301
The role of cholecystokinin (CCK), CCK-A or CCK-B receptor antagonists in the spontaneous preference for drugs of abuse (alcohol or cocaine) in naive rats. Methods and findings in experimental and clinical pharmacology 19981001
Involvement of endogenous cholecystokinin and somatostatin in gastroprotection induced by intraduodenal fat. Journal of clinical gastroenterology 19980101
Peripheral administration of cholecystokinin activates c-fos expression in the locus coeruleus/subcoeruleus nucleus, dorsal vagal complex and paraventricular nucleus via capsaicin-sensitive vagal afferents and CCK-A receptors in the rat. Brain research 19971003
Optimization of 3-(1H-indazol-3-ylmethyl)-1,5-benzodiazepines as potent, orally active CCK-A agonists. Journal of medicinal chemistry 19970815
Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor. Journal of medicinal chemistry 19970227
YF476 is a new potent and selective gastrin/cholecystokinin-B receptor antagonist in vitro and in vivo. Alimentary pharmacology & therapeutics 19970201
(3R)-N-(1-(tert-butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl)-N'-(3-(methylamino)phenyl)urea (YF476): a potent and orally active gastrin/CCK-B antagonist. Journal of medicinal chemistry 19970131
Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release. Proceedings of the National Academy of Sciences of the United States of America 19961015
Pharmacological profile of T-0632, a novel potent and selective CCKA receptor antagonist, in vitro. European journal of pharmacology 19960523
Pharmacological profile of TP-680, a new cholecystokininA receptor antagonist. British journal of pharmacology 19960401
Controlled modification of acidity in cholecystokinin B receptor antagonists: N-(1,4-benzodiazepin-3-yl)-N'-[3-(tetrazol-5-ylamino) phenyl]ureas. Journal of medicinal chemistry 19960216
Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity. 1. Optimization of the agonist 'trigger'. Journal of medicinal chemistry 19960119
His381 of the rat CCKB receptor is essential for CCKB versus CCKA receptor antagonist selectivity. European journal of pharmacology 19960118
The in vivo metabolism of cholecystokinin (CCK-8) is essentially ensured by aminopeptidase A. Peptides 19960101
CCKB receptor activation results in increased [3H]thymidine incorporation in rat glioma C6 cells. Neuropeptides 19951101
Comparison of cholecystokinin, pentagastrin, and duodenal oleate in gastroprotection in rats. Scandinavian journal of gastroenterology 19950701
Behavioural effects of two cholecystokinin analogues: JMV 236 and JMV 179. Neuropeptides 19940901
Characterization of cholecystokininA receptor agonist activity by a family of cholecystokininB receptor antagonists. The Journal of pharmacology and experimental therapeutics 19940601
Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo. The Journal of pharmacology and experimental therapeutics 19940501
Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide. The Journal of pharmacology and experimental therapeutics 19940201
Localisation of sulfakinin neuronal pathways in the blowfly Calliphora vomitoria. Cell and tissue research 19940101
Effect of pinaverium and other calcium channel blockers on contraction of isolated gastric antral smooth muscle cells caused by gastrointestinal hormones. Life sciences 19940101
Synthesis and biological evaluation of cholecystokinin analogs in which the Asp-Phe-NH2 moiety has been replaced by a 3-amino-7-phenylheptanoic acid or a 3-amino-6-(phenyloxy)hexanoic acid. Journal of medicinal chemistry 19931001
Functional characterization of a human brain cholecystokinin-B receptor. A trophic effect of cholecystokinin and gastrin. The Journal of biological chemistry 19930825
Cholecystokinin increases intracellular Ca2+ concentration in the Human JURKAT T Lymphocyte cell line. European journal of pharmacology 19930515
The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization. The Journal of biological chemistry 19930415
[3H]PD 140376: a novel and highly selective antagonist radioligand for the cholecystokininB/gastrin receptor in guinea pig cerebral cortex and gastric mucosa. Molecular pharmacology 19930401
Cholecystokinin dipeptoid antagonists: design, synthesis, and anxiolytic profile of some novel CCK-A and CCK-B selective and 'mixed' CCK-A/CCK-B antagonists. Journal of medicinal chemistry 19930305
Tetronothiodin, a novel CCKB receptor ligand, antagonizes cholecystokinin-induced Ca2+ mobilization in a pituitary cell line. European journal of pharmacology 19921006
Behavioral effects of A71623, a highly selective CCK-A agonist tetrapeptide. The American journal of physiology 19920701
[3H]pBC 264, a suitable probe for studying cholecystokinin-B receptors: binding characteristics in rodent brains and comparison with [3H]SNF 8702. Molecular pharmacology 19920601
Replacement of Tyr-SO3H by a p-carboxymethyl-phenylalanine in a CCK8-derivative preserves its high affinity for CCK-B receptor. International journal of peptide and protein research 19920101
Human brain leucyl aminopeptidase: isolation, characterization and specificity against some neuropeptides. Neuropeptides 19910701
Boc-Trp-Orn(Z)-Asp-NH2 and derivatives: a new family of CCK antagonists. Journal of medicinal chemistry 19901201
Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity. Proceedings of the National Academy of Sciences of the United States of America 19900901
CCK-8S inhibits L-dopa-induced dyskinesias in parkinsonian squirrel monkeys. Neurology 19900401
Correlation between phospholipid breakdown, intracellular calcium mobilization and enzyme secretion in rat pancreatic acini treated with Boc-[Nle28, Nle31]-CCK-7 and JMV180, two cholecystokinin analogues. Cellular signalling 19900101
Synthesis and binding affinities of cyclic and related linear analogues of CCK8 selective for central receptors. Journal of medicinal chemistry 19890601
CCK-JMV-180: a peptide that distinguishes high-affinity cholecystokinin receptors from low-affinity cholecystokinin receptors. Biochimica et biophysica acta 19890209
Electrophysiological studies with new CCK analogs: correlation with binding affinity on B-type receptors. Peptides 19890101
Progesterone receptors regulate gallbladder motility. The Journal of surgical research 19881201
Conformational analysis of possible biologically active (receptor-bound) conformations of peptides derived from cholecystokinin, cerulein and little gastrin and the opiate peptide, Met-enkephalin. Peptides 19880101
Investigation of peripheral cholecystokinin receptor heterogeneity by cyclic and related linear analogues of CCK26-33: synthesis and biological properties. Journal of medicinal chemistry 19870601
Behavioral evidence for the involvement of endogenous opioids in the interaction between cholecystokinin and brain dopamine systems. Neuroscience letters 19870309
CCK-5: sequence analysis of a small cholecystokinin from canine brain and intestine. The American journal of physiology 19870201
CR-1409: a potent inhibitor of cholecystokinin-stimulated amylase release and cholecystokinin binding in rat pancreatic acini. Pancreas 19870101
A behavioral pharmacological study on CCK-8 related peptides in mice. Neuropeptides 19861001
Isolation, structure and properties of the C-terminal flanking peptide of preprocholecystokinin from rat brain. FEBS letters 19860818
Conformational analysis of cholecystokinin CCK26-33 and related fragments by 1H NMR spectroscopy, fluorescence-transfer measurements, and calculations. Biochemistry 19860701
Inhibition of haloperidol-induced catalepsy by cholecystokinin octapeptides after central administration to rats. Neuropharmacology 19850601
Cataleptogenic and anticataleptic activity produced by cholecystokinin octapeptides in mice. Neuropeptides 19850601
Isolation of a large cholecystokinin precursor from canine brain. Proceedings of the National Academy of Sciences of the United States of America 19841101
Inhibition of seizures induced by picrotoxin and electroshock by cholecystokinin octapeptides and their fragments in rats after intracerebroventricular administration. Neuropharmacology 19840801
Structure-activity and dose-effect relationships of the antagonism of picrotoxin-induced seizures by cholecystokinin, fragments and analogues of cholecystokinin in mice. Neuropharmacology 19831001
Sedative action of cholecystokinin octapeptide on behavioral excitation by thyrotropin releasing hormone and methamphetamine in the rat. The Japanese journal of physiology 19820101
Anticonvulsant effects of caerulein, cholecystokinin octapeptide (CCK-8) and diazepam against seizures produced in mice by harman, thiosemicarbazide and isoniazid. Neuroscience letters 19810702
Degradation of cholecystokinin-like peptides by a crude rat brain synaptosomal fraction: a study by high pressure liquid chromatography. Regulatory peptides 19810401
Properties