Home Other Building Blocks 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-

CAS No.:
249296-44-4
Catalog Number:
AG002PWQ
Molecular Formula:
C13H13N3
Molecular Weight:
211.2624
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$173
- +
10mg
99%
1 week
United States
$223
- +
25mg
99%
1 week
United States
$373
- +
50mg
99%
1 week
United States
$557
- +
100mg
99%
1 week
United States
$890
- +
Product Description
Catalog Number:
AG002PWQ
Chemical Name:
6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-
CAS Number:
249296-44-4
Molecular Formula:
C13H13N3
Molecular Weight:
211.2624
MDL Number:
MFCD10001497
IUPAC Name:
5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene
InChI:
InChI=1S/C13H13N3/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1/h1-2,4-5,8-9,14H,3,6-7H2
InChI Key:
JQSHBVHOMNKWFT-UHFFFAOYSA-N
SMILES:
N1CC2CC(C1)c1c2cc2c(c1)nccn2
Properties
Complexity:
254  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
211.111g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
211.268g/mol
Monoisotopic Mass:
211.111g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
37.8A^2
Undefined Atom Stereocenter Count:
2  
Undefined Bond Stereocenter Count:
0
XLogP3:
0.8  
Literature
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Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex. Neurochemistry international 20110101
Parallel anxiolytic-like effects and upregulation of neuronal nicotinic acetylcholine receptors following chronic nicotine and varenicline. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110101
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The high-affinity nAChR partial agonists varenicline and sazetidine-A exhibit reinforcing properties in rats. Progress in neuro-psychopharmacology & biological psychiatry 20101201
Drug discrimination in methamphetamine-trained rats: effects of cholinergic nicotinic compounds. The Journal of pharmacology and experimental therapeutics 20101201
The nicotinic acetylcholine receptor partial agonist varenicline increases the ataxic and sedative-hypnotic effects of acute ethanol administration in C57BL/6J mice. Alcoholism, clinical and experimental research 20101201
Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis. Trends in pharmacological sciences 20101201
A review of the clinical pharmacokinetics and pharmacodynamics of varenicline for smoking cessation. Clinical pharmacokinetics 20101201
Varenicline-induced grand mal seizure. Epileptic disorders : international epilepsy journal with videotape 20101201
Thiopurine S-methyltransferase deficiency associated with a novel mutation. Inflammatory bowel diseases 20101101
Immediate versus delayed quitting and rates of relapse among smokers treated successfully with varenicline, bupropion SR or placebo. Addiction (Abingdon, England) 20101101
Mental health stability in veterans with posttraumatic stress disorder receiving varenicline. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101101
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Comparison of available treatments for tobacco addiction. Current psychiatry reports 20101001
A pilot study to assess smokeless tobacco use reduction with varenicline. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20101001
Nicotine gum dependence treated with varenicline--a case report. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20101001
Clinical experience of varenicline for smoking cessation. The clinical respiratory journal 20101001
A brief review of pharmacotherapeutic treatment options in smoking cessation: bupropion versus varenicline. Journal of the American Academy of Nurse Practitioners 20101001
Relapse prevention in UK Stop Smoking Services: current practice, systematic reviews of effectiveness and cost-effectiveness analysis. Health technology assessment (Winchester, England) 20101001
Varenicline (champix)-associated manic relapse in bipolar affective disorder. Irish medical journal 20101001
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