Home Carboxys 9-Oxo-9,10-dihydroacridine-4-carboxylic acid

9-Oxo-9,10-dihydroacridine-4-carboxylic acid

CAS No.:
24782-64-7
Catalog Number:
AG002PFH
Molecular Formula:
C14H9NO3
Molecular Weight:
239.2262
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
96%
1 week
United States
$163
- +
1g
96%
1 week
United States
$288
- +
Product Description
Catalog Number:
AG002PFH
Chemical Name:
9-Oxo-9,10-dihydroacridine-4-carboxylic acid
CAS Number:
24782-64-7
Molecular Formula:
C14H9NO3
Molecular Weight:
239.2262
MDL Number:
MFCD00957937
IUPAC Name:
9-oxo-10H-acridine-4-carboxylic acid
InChI:
InChI=1S/C14H9NO3/c16-13-8-4-1-2-7-11(8)15-12-9(13)5-3-6-10(12)14(17)18/h1-7H,(H,15,16)(H,17,18)
InChI Key:
BATAOFZEDHPRTM-UHFFFAOYSA-N
SMILES:
OC(=O)c1cccc2c1[nH]c1ccccc1c2=O
Properties
Complexity:
368  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
239.058g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
239.23g/mol
Monoisotopic Mass:
239.058g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
66.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.5  
Literature
Title Journal
Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation. Bioorganic & medicinal chemistry letters 20110615
9-Acridone-4-carboxylic acid as an efficient Cr(III) fluorescent sensor: trace level detection, estimation and speciation studies. Journal of hazardous materials 20110415
The acridone derivative MBLI-87 sensitizes breast cancer resistance protein-expressing xenografts to irinotecan. European journal of cancer (Oxford, England : 1990) 20110301
Spectroscopic, structural and theoretical studies of novel, potentially cytotoxic 4-acridonecarboxamide imines. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090715
Design, synthesis and evaluations of acridone derivatives using Candida albicans--search for MDR modulators led to the identification of an anti-candidiasis agent. Bioorganic & medicinal chemistry 20090601
Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2. Bioorganic & medicinal chemistry 20070415
Synthesis and evaluation of acridine- and acridone-based anti-herpes agents with topoisomerase activity. Bioorganic & medicinal chemistry 20060815
Properties