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Senegenin

CAS No.:
2469-34-3
Catalog Number:
AG002P1J
Molecular Formula:
C30H45ClO6
Molecular Weight:
537.1277
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
99%(HPLC)
In Stock USA
United States
$53
- +
5mg
99%(HPLC)
In Stock USA
United States
$118
- +
25mg
99%(HPLC)
In Stock USA
United States
$408
- +
Product Description
Catalog Number:
AG002P1J
Chemical Name:
Senegenin
CAS Number:
2469-34-3
Molecular Formula:
C30H45ClO6
Molecular Weight:
537.1277
MDL Number:
MFCD00466906
IUPAC Name:
(2S,3R,4S,4aR,6aR,8aS,12aS,13S,14aR,14bR)-13-(chloromethyl)-2,3-dihydroxy-4,6a,11,11,14b-pentamethyl-2,3,4a,5,6,7,8,9,10,12,12a,13,14,14a-tetradecahydro-1H-picene-4,8a-dicarboxylic acid
InChI:
InChI=1S/C30H45ClO6/c1-26(2)10-11-30(25(36)37)9-6-17-22(18(30)13-26)16(15-31)12-21-27(17,3)8-7-20-28(21,4)14-19(32)23(33)29(20,5)24(34)35/h16,18-21,23,32-33H,6-15H2,1-5H3,(H,34,35)(H,36,37)/t16-,18+,19+,20-,21+,23+,27+,28+,29+,30-/m1/s1
InChI Key:
CWHJIJJSDGEHNS-MYLFLSLOSA-N
SMILES:
ClC[C@H]1C[C@H]2[C@@](C3=C1[C@H]1CC(C)(C)CC[C@@]1(CC3)C(=O)O)(C)CCC1[C@]2(C)C[C@H](O)[C@@H]([C@]1(C)C(=O)O)O
UNII:
06S1QH951L
Properties
Complexity:
1040  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Defined Bond Stereocenter Count:
0
Exact Mass:
536.29g/mol
Formal Charge:
0
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
537.134g/mol
Monoisotopic Mass:
536.29g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
115A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.1  
Literature
Title Journal
Tenuigenin protects dopaminergic neurons from inflammation-mediated damage induced by the lipopolysaccharide. CNS neuroscience & therapeutics 20120701
Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats. PloS one 20120101
Neuroprotective effects of tenuigenin in a SH-SY5Y cell model with 6-OHDA-induced injury. Neuroscience letters 20110622
Tenuigenin protects cultured hippocampal neurons against methylglyoxal-induced neurotoxicity. European journal of pharmacology 20101025
Tenuifolin, an extract derived from tenuigenin, inhibits amyloid-beta secretion in vitro. Acta physiologica (Oxford, England) 20090801
[The protective effects of tenuigenin on the PC12 cells injury induced by H2O2]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070801
[Protective effect of tenuigenin on cytotoxicity of primary cultures of cortical neurons induced by amyloid beta-protein 1-40 (Abeta(1-40))]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070701
Tenuigenin treatment decreases secretion of the Alzheimer's disease amyloid beta-protein in cultured cells. Neuroscience letters 20040826
Properties