1,4-Naphthalenedione, 2-[(1R)-1-(acetyloxy)-4-methyl-3-penten-1-yl]-5,8-dihydroxy-
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Lithospermum erythrorhizon suppresses high-fat diet-induced obesity, and acetylshikonin, a main compound of Lithospermum erythrorhizon, inhibits adipocyte differentiation. | Journal of agricultural and food chemistry 20120912 |
Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. | Journal of natural products 20120525 |
Ionization of shikonin derivatives using negative-ion electrospray mass spectrometry: [M-H]- versus [M + e]•-. | Journal of mass spectrometry : JMS 20120501 |
Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. | Bioorganic & medicinal chemistry 20120301 |
Callus culture of Echium italicum L. towards production of a shikonin derivative. | Natural product research 20110901 |
The anti-proliferation effect of Aikete injection on hepatocellular carcinoma in vitro and in vivo. | Pharmaceutical biology 20110501 |
Simultaneous densitometric determination of shikonin, acetylshikonin, and beta-acetoxyisovaleryl-shikonin in ultrasonic-assisted extracts of four Arnebia species using reversed-phase thin layer chromatography. | Journal of separation science 20090901 |
Inhibitory effect of acetylshikonin on human gastric carcinoma cell line SGC-7901 in vitro and in vivo. | World journal of gastroenterology 20090421 |
The influence of acetylshikonin, a natural naphthoquinone, on the production of leukotriene B4 and thromboxane A2 in rat neutrophils. | European journal of pharmacology 20090401 |
Quantitative determination of acetylshikonin in macaque monkey blood by LC-ESI-MS/MS after precolumn derivatization with 2-mercaptoethanol and its application in pharmacokinetic study. | Acta pharmacologica Sinica 20081201 |
Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. | Cancer research 20081101 |
Shikonin, acetylshikonin, and isobutyroylshikonin inhibit VEGF-induced angiogenesis and suppress tumor growth in lewis lung carcinoma-bearing mice. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081101 |
Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones. | European journal of medicinal chemistry 20080601 |
Isolation and purification of acetylshikonin and beta-acetoxyisovalerylshikonin from cell suspension cultures of Arnebia euchroma (Royle) Johnston using rapid preparative HPLC. | Journal of separation science 20080301 |
Synthetic 2',5'-dimethoxychalcones as G(2)/M arrest-mediated apoptosis-inducing agents and inhibitors of nitric oxide production in rat macrophages. | European journal of medicinal chemistry 20070501 |
Human ACAT inhibitory effects of shikonin derivatives from Lithospermum erythrorhizon. | Bioorganic & medicinal chemistry letters 20070215 |
Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma leptantha. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20060301 |
The effect of acetylshikonin isolated from Lithospermum canescens roots on tumor-induced cutaneous angiogenesis. | Acta poloniae pharmaceutica 20040101 |
Antimicrobial activities of naphthazarins from Arnebia euchroma. | Journal of natural products 20021201 |
Shikonin derivatives: synthesis and inhibition of human telomerase. | Bioorganic & medicinal chemistry letters 20020520 |