Home Sulfos 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide

4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide

CAS No.:
2447-57-6
Catalog Number:
AG002O8V
Molecular Formula:
C12H14N4O4S
Molecular Weight:
310.3290
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$25
- +
25g
98%
In Stock USA
United States
$50
- +
100g
98%
In Stock USA
United States
$82
- +
500g
98%
In Stock USA
United States
$244
- +
Product Description
Catalog Number:
AG002O8V
Chemical Name:
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide
CAS Number:
2447-57-6
Molecular Formula:
C12H14N4O4S
Molecular Weight:
310.3290
MDL Number:
MFCD00792890
IUPAC Name:
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
InChI:
InChI=1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI Key:
PJSFRIWCGOHTNF-UHFFFAOYSA-N
SMILES:
COc1c(OC)ncnc1NS(=O)(=O)c1ccc(cc1)N
EC Number:
219-504-9
UNII:
88463U4SM5
NSC Number:
759319
Properties
Complexity:
420  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
310.074g/mol
Formal Charge:
0
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
310.328g/mol
Monoisotopic Mass:
310.074g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
125A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.7  
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A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania. Malaria journal 20110101
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Effect of transmission reduction by insecticide-treated bednets (ITNs) on antimalarial drug resistance in western Kenya. PloS one 20110101
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Piloting the global subsidy: the impact of subsidized artemisinin-based combination therapies distributed through private drug shops in rural Tanzania. PloS one 20090101
PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria. Malaria journal 20090101
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Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial. Malaria journal 20090101
A simple cost-effective high performance liquid chromatographic assay of sulphadoxine in whole blood spotted on filter paper for field studies. Malaria journal 20090101
Transparency in Nigeria's public pharmaceutical sector: perceptions from policy makers. Globalization and health 20090101
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Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda. Malaria journal 20090101
Self-reported data: a major tool to assess compliance with anti-malarial combination therapy among children in Senegal. Malaria journal 20090101
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Making stillbirths count, making numbers talk - issues in data collection for stillbirths. BMC pregnancy and childbirth 20090101
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A trial of combination antimalarial therapies in children from Papua New Guinea. The New England journal of medicine 20081211
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Prevalence of polymorphisms in DHFR, DHPS, PFMDR1 and PFCRT genes of Plasmodium falciparum isolates in Quang Tri Province, Vietnam. The Southeast Asian journal of tropical medicine and public health 20081101
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A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana. The Journal of infectious diseases 20081015
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Therapeutic effect of a novel oxazolidinone, DA-7867, in BALB/c mice infected with Nocardia brasiliensis. PLoS neglected tropical diseases 20080901
A 12-year retrospective study of non-burn skin loss (burn-like syndromes) at a tertiary burns unit in a developing country. Burns : journal of the International Society for Burn Injuries 20080801
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Impact of intermittent preventive treatment with sulfadoxine-pyrimethamine on antibody responses to erythrocytic-stage Plasmodium falciparum antigens in infants in Mozambique. Clinical and vaccine immunology : CVI 20080801
Molecular markers of in vivo Plasmodium vivax resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1. The Journal of infectious diseases 20080801
Adherence and effectiveness of drug combination in curative treatment among children suffering uncomplicated malaria in rural Senegal. Transactions of the Royal Society of Tropical Medicine and Hygiene 20080801
Anti malarial drugs for prevention of malaria. Indian pediatrics 20080801
Poor knowledge on new malaria treatment guidelines among drug dispensers in private pharmacies in Tanzania: the need for involving the private sector in policy preparations and implementation. East African journal of public health 20080801
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Flow cytometric immunoassay for sulfonamides in raw milk. Analytica chimica acta 20080714
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Dihydrofolate reductase I164L mutation in Plasmodium falciparum, Madagascar. Emerging infectious diseases 20080701
Surveillance for adverse drug reactions to combination antimalarial therapy with sulfadoxine-pyrimethamine plus artesunate in Peru. The American journal of tropical medicine and hygiene 20080701
Molecular markers of resistance to sulfadoxine-pyrimethamine during intermittent preventive treatment for malaria in Mozambican infants. The Journal of infectious diseases 20080615
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New medicines for tropical diseases in pregnancy: catch-22. PLoS medicine 20080601
Association between anaemia during pregnancy and blood loss at and after delivery among women with vaginal births in Pemba Island, Zanzibar, Tanzania. Journal of health, population, and nutrition 20080601
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[Comparative impact of three malaria preventive regimens during pregnancy on maternal anemia due to malaria in Burkina Faso]. Medecine et maladies infectieuses 20080401
Population pharmacokinetics of chloroquine and sulfadoxine and treatment response in children with malaria: suggestions for an improved dose regimen. British journal of clinical pharmacology 20080401
Malaria in African schoolchildren: options for control. Transactions of the Royal Society of Tropical Medicine and Hygiene 20080401
Dihydrofolate reductase I164L mutations in Plasmodium falciparum isolates: clinical outcome of 14 Kenyan adults infected with parasites harbouring the I164L mutation. Transactions of the Royal Society of Tropical Medicine and Hygiene 20080401
Assessment of the therapeutic efficacy of chloroquine in the treatment of uncomplicated Plasmodium falciparum malaria in a tribal block of the Kalahandi district of Orissa, India. Tropical doctor 20080401
Herba Artemisiae annuae tea preparation compared to sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria in adults: a randomized double-blind clinical trial. Tropical doctor 20080401
Artemether + lumefantrine: new drug. An alternative to atovaquone + proguanil. Prescrire international 20080401
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[Assessing the application of Rwanda's national protocol for uncomplicated malaria treatment in healthcare institutions in Kigali City, Rwanda]. Medecine et maladies infectieuses 20080301
Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae. The American journal of tropical medicine and hygiene 20080301
Efficacy, safety, and selection of molecular markers of drug resistance by two ACTs in Mali. The American journal of tropical medicine and hygiene 20080301
[Efficacy of the amodiaquine+sulfadoxine-pyrimethamine combination and of chloroquine for the treatment of malaria in Córdoba, Colombia, 2006]. Biomedica : revista del Instituto Nacional de Salud 20080301
Antimalarial resistance and DHFR/DHPS genotypes of Plasmodium falciparum three years after introduction of sulfadoxine-pyrimethamine and amodiaquine in rural Tanzania. Transactions of the Royal Society of Tropical Medicine and Hygiene 20080201
A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia. PLoS medicine 20080201
Intermittent preventive treatment of malaria in pregnancy: a new delivery system and its effect on maternal health and pregnancy outcomes in Uganda. Bulletin of the World Health Organization 20080201
Access and barriers to measures targeted to prevent malaria in pregnancy in rural Kenya. Tropical medicine & international health : TM & IH 20080201
Chloroquine resistant Plasmodium falciparum malaria in Osogbo Nigeria: efficacy of amodiaquine + sulfadoxine-pyrimethamine and chloroquine + chlorpheniramine for treatment. Memorias do Instituto Oswaldo Cruz 20080201
Intermittent preventive treatment of malaria in pregnancy: a community-based delivery system and its effect on parasitemia, anemia and low birth weight in Uganda. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20080101
How antimalarial drug resistance affects post-treatment prophylaxis. Malaria journal 20080101
Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria. Malaria journal 20080101
A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children. PloS one 20080101
Sulphadoxine/pyrimethamine versus amodiaquine for treating uncomplicated childhood malaria in Gabon: a randomized trial to guide national policy. Malaria journal 20080101
Sulfadoxine-pyrimethamine-based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi. PloS one 20080101
Household cost of malaria overdiagnosis in rural Mozambique. Malaria journal 20080101
Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso. PloS one 20080101
Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine. Malaria journal 20080101
Use of antenatal care, maternity services, intermittent presumptive treatment and insecticide treated bed nets by pregnant women in Luwero district, Uganda. Malaria journal 20080101
Real-time PCR/MCA assay using fluorescence resonance energy transfer for the genotyping of resistance related DHPS-540 mutations in Plasmodium falciparum. Malaria journal 20080101
Guidelines and mindlines: why do clinical staff over-diagnose malaria in Tanzania? A qualitative study. Malaria journal 20080101
Can changes in malaria transmission intensity explain prolonged protection and contribute to high protective efficacy of intermittent preventive treatment for malaria in infants? Malaria journal 20080101
A randomized placebo-controlled trial of intermittent preventive treatment in pregnant women in the context of insecticide treated nets delivered through the antenatal clinic. PloS one 20080101
Efficacy of amodiaquine in the treatment of uncomplicated falciparum malaria in young children of rural north-western Burkina Faso. Malaria journal 20080101
The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus sulphadoxine-pyrimethamine against falciparum malaria in Papua New Guinea. Malaria journal 20080101
Malaria in pregnancy: a literature review. Journal of midwifery & women's health 20080101
Heterogeneous distribution of Plasmodium falciparum drug resistance haplotypes in subsets of the host population. Malaria journal 20080101
Iron incorporation and post-malaria anaemia. PloS one 20080101
Evidence for over-dispersion in the distribution of clinical malaria episodes in children. PloS one 20080101
Duration of protection against malaria and anaemia provided by intermittent preventive treatment in infants in Navrongo, Ghana. PloS one 20080101
Escalating Plasmodium falciparum antifolate drug resistance mutations in Macha, rural Zambia. Malaria journal 20080101
A structural annotation resource for the selection of putative target proteins in the malaria parasite. Malaria journal 20080101
Plasmodium vivax trophozoites insensitive to chloroquine. Malaria journal 20080101
Substandard anti-malarial drugs in Burkina Faso. Malaria journal 20080101
Acute pancreatitis and subdural haematoma in a patient with severe falciparum malaria: case report and review of literature. Malaria journal 20080101
Study protocol for a three-armed randomized controlled trial to assess whether house screening can reduce exposure to malaria vectors and reduce malaria transmission in The Gambia. Trials 20080101
Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children. Malaria journal 20080101
[Cerebral symptomatic toxoplasmosis treated by sulfadoxine/pyrimethamine treatment. About 6 patients]. Therapie 20080101
Acceptability of evidence-based neonatal care practices in rural Uganda - implications for programming. BMC pregnancy and childbirth 20080101
Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique. Malaria journal 20080101
The challenges of diagnosis and treatment of malaria in pregnancy in low resource settings. Acta obstetricia et gynecologica Scandinavica 20080101
Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season on the incidence of clinical malaria in children in Mali. Malaria journal 20080101
Antimalarial drug use in general populations of tropical Africa. Malaria journal 20080101
Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. Malaria journal 20080101
Role of co-trimoxazole prophylaxis in reducing mortality in HIV infected adults being treated for tuberculosis: randomised clinical trial. BMJ (Clinical research ed.) 20080101
Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants. PloS one 20080101
Malaria in pregnant women in an area with sustained high coverage of insecticide-treated bed nets. Malaria journal 20080101
Molecular epidemiology of drug-resistant malaria in western Kenya highlands. BMC infectious diseases 20080101
From strategy development to routine implementation: the cost of Intermittent Preventive Treatment in Infants for malaria control. BMC health services research 20080101
Toxoplasma granuloma of brainstem: a rare case. Neurology India 20080101
Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children. Malaria journal 20080101
Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate. BMC genomics 20080101
Should countries implementing an artemisinin-based combination malaria treatment policy also introduce rapid diagnostic tests? Malaria journal 20080101
A community effectiveness trial of strategies promoting intermittent preventive treatment with sulphadoxine-pyrimethamine in pregnant women in rural Burkina Faso. Malaria journal 20080101
Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: a report from three study sites in sub-Saharan Africa. Malaria journal 20080101
Development of behaviour change communication strategy for a vaccination-linked malaria control tool in southern Tanzania. Malaria journal 20080101
Costs and cost-effectiveness of delivering intermittent preventive treatment through schools in western Kenya. Malaria journal 20080101
Therapeutic and prophylactic effect of intermittent preventive anti-malarial treatment in infants (IPTi) from Ghana and Gabon. Malaria journal 20080101
A nationwide survey of the quality of antimalarials in retail outlets in Tanzania. PloS one 20080101
The acceptability of intermittent preventive treatment of malaria in infants (IPTi) delivered through the expanded programme of immunization in southern Tanzania. Malaria journal 20080101
Willingness and ability to pay for artemisinin-based combination therapy in rural Tanzania. Malaria journal 20080101
Spread of anti-malarial drug resistance: mathematical model with implications for ACT drug policies. Malaria journal 20080101
Implementation of intermittent preventive treatment in pregnancy with sulphadoxine/pyrimethamine (IPTp-SP) at a district health centre in rural Senegal. Malaria journal 20080101
Importance of pre-analytical factors contributing to measurement uncertainty, when determining sulfadoxine and sulfamethoxazole from capillary blood dried on sampling paper. Journal of chromatographic science 20080101
Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola. Malaria journal 20080101
A randomized trial to monitor the efficacy and effectiveness by QT-NASBA of artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment and transmission control of uncomplicated Plasmodium falciparum malaria in western Kenya. Malaria journal 20080101
Evaluation of the efficacy and safety of artemether-lumefantrine in the treatment of acute uncomplicated Plasmodium falciparum malaria in Nigerian infants and children. Malaria journal 20080101
Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity. Malaria journal 20080101
Acceptance of ACTs by patients in private healthcare facilities in Surulere, Lagos State. Nigerian quarterly journal of hospital medicine 20080101
Opposed circulating plasma levels of endothelin-1 and C-type natriuretic peptide in children with Plasmodium falciparum malaria. Malaria journal 20080101
Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy. Malaria journal 20080101
Individual, facility and policy level influences on national coverage estimates for intermittent preventive treatment of malaria in pregnancy in Tanzania. Malaria journal 20080101
Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial. PloS one 20080101
High risk of severe anaemia after chlorproguanil-dapsone+artesunate antimalarial treatment in patients with G6PD (A-) deficiency. PloS one 20080101
[Pediatric management of sickle cell disease: experience at the Charles de Gaulle University Children's Hospital in Ouagadougou (Burkina Faso)]. Sante (Montrouge, France) 20080101
Challenges Associated with Scaling up Artemisinin Combination Therapy in Sub-Saharan Africa A Review Article. The Libyan journal of medicine 20080101
[Dietary recommendations with practical examples of menus for people living with HIV/AIDS in sub-Saharan Africa]. The Pan African medical journal 20080101
Locked-in Syndrome in a Nigerian male with Multiple Sclerosis: a case report and literature review. The Pan African medical journal 20080101
High-performance liquid chromatographic assay for the determination of sulfadoxine and N-acetyl sulfadoxine in plasma from patients infected with sensitive and resistant Plasmodium falciparum malaria. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071215
Pyrimethamine treatment does not ameliorate lymphoproliferation or autoimmune disease in MRL/lpr-/- mice or in patients with autoimmune lymphoproliferative syndrome. American journal of hematology 20071201
Home-based management of fever and malaria treatment practices in Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene 20071201
Ibuprofen does not affect levels of tumor necrosis factor alpha and soluble tumor necrosis factor receptor types I and II in Gabonese children with uncomplicated Plasmodium falciparum malaria. European cytokine network 20071201
Randomized comparison of amodiaquine plus sulfadoxine-pyrimethamine, artemether-lumefantrine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Burkina Faso. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071201
Intermittent preventive therapy with sulfadoxine-pyrimethamine during pregnancy: seeking information on optimal dosing frequency. The Journal of infectious diseases 20071201
Inferiority of single-dose sulfadoxine-pyrimethamine intermittent preventive therapy for malaria during pregnancy among HIV-positive Zambian women. The Journal of infectious diseases 20071201
Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine in HIV-seropositive pregnant Zambian women. The Journal of infectious diseases 20071201
Intermittent preventive treatment against malaria in infants in Gabon--a randomized, double-blind, placebo-controlled trial. The Journal of infectious diseases 20071201
Malaria and anaemia among pregnant women at first antenatal clinic visit in Kisumu, western Kenya. Tropical medicine & international health : TM & IH 20071201
Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis. The American journal of tropical medicine and hygiene 20071201
Malaria in Egypt, Saudi Arabia and Yemen: a clinical pilot study. Journal of the Egyptian Society of Parasitology 20071201
Sulfadoxine-pyrimethamine plus artesunate compared with chloroquine for the treatment of vivax malaria in areas co-endemic for Plasmodium falciparum and P. vivax: a randomised non-inferiority trial in eastern Afghanistan. Transactions of the Royal Society of Tropical Medicine and Hygiene 20071101
A community-based delivery system of intermittent preventive treatment of malaria in pregnancy and its effect on use of essential maternity care at health units in Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene 20071101
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance. Clinical pharmacology and therapeutics 20071101
Pharmacokinetics of sulfadoxine-pyrimethamine in HIV-infected and uninfected pregnant women in Western Kenya. The Journal of infectious diseases 20071101
Comparison of the therapeutic efficacy of chloroquine and sulphadoxine-pyremethamine in children and pregnant women. Tropical medicine & international health : TM & IH 20071101
Low efficacy of amodiaquine or chloroquine plus sulfadoxine-pyrimethamine against Plasmodium falciparum and P. vivax malaria in Papua New Guinea. The American journal of tropical medicine and hygiene 20071101
Intermittent preventive treatment of malaria during pregnancy in central Mozambique. Bulletin of the World Health Organization 20071101
Simple multiresidue method for monitoring of trimethoprim and sulfonamide residues in buffalo meat by high-performance liquid chromatography. Journal of agricultural and food chemistry 20071031
Ethnographic study of factors influencing compliance to intermittent preventive treatment of malaria during pregnancy among Yao women in rural Malawi. Transactions of the Royal Society of Tropical Medicine and Hygiene 20071001
Antimalarial drug quality in Africa. Journal of clinical pharmacy and therapeutics 20071001
Immune responses after single-dose sulphadoxine-pyrimethamine indicate underestimation of protective efficacy of intermittent preventive treatment in infants. Tropical medicine & international health : TM & IH 20071001
Therapeutic efficacy of sulfadoxine-pyrimethamine and the prevalence of molecular markers of resistance in under 5-year olds in Brazzaville, Congo. Tropical medicine & international health : TM & IH 20071001
Comparison of different artemisinin-based combinations for the treatment of Plasmodium falciparum malaria in children in Kigali, Rwanda, an area of resistance to sulfadoxine-pyrimethamine: artesunate plus sulfadoxine/pyrimethamine versus artesunate plus sulfamethoxypyrazine/pyrimethamine. The American journal of tropical medicine and hygiene 20071001
Malaria treatment efficacy among people living with HIV: the role of host and parasite factors. The American journal of tropical medicine and hygiene 20071001
Appraisal on the prevalence of malaria and anaemia in pregnancy and factors influencing uptake of intermittent preventive therapy with sulfadoxine-pyrimethamine in Kibaha district, Tanzania. East African journal of public health 20071001
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High prevalence of molecular markers for resistance to chloroquine and pyrimethamine in Plasmodium falciparum from Zimbabwe. Parasitology research 20070901
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Value of Toxoplasma gondii detection in one hundred thirty-three placentas for the diagnosis of congenital toxoplasmosis. The Pediatric infectious disease journal 20070901
Comparison of artemether-lumefantrine with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in eastern Nepal. The American journal of tropical medicine and hygiene 20070901
Selection of antifolate-resistant Plasmodium falciparum by sulfadoxine-pyrimethamine treatment and infectivity to Anopheles mosquitoes. The American journal of tropical medicine and hygiene 20070901
Molecular epidemiology of malaria in Cameroon. XXVII. Clinical and parasitological response to sulfadoxine-pyrimethamine treatment and Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase alleles in Cameroonian children. Acta tropica 20070801
The effect of health care worker training on the use of intermittent preventive treatment for malaria in pregnancy in rural western Kenya. Tropical medicine & international health : TM & IH 20070801
Perception and practice of malaria prophylaxis in pregnancy among health care providers in Ibadan. African journal of reproductive health 20070801
Characterisation of exogenous folate transport in Plasmodium falciparum. Molecular and biochemical parasitology 20070701
A randomized controlled trial of extended intermittent preventive antimalarial treatment in infants. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070701
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Dramatically decreased therapeutic efficacy of chloroquine and sulfadoxine-pyrimethamine, but not mefloquine, in southern Benin. Tropical medicine & international health : TM & IH 20070701
Combined molecular and clinical assessment of Plasmodium falciparum antimalarial drug resistance in the Lao People's Democratic Republic (Laos). The American journal of tropical medicine and hygiene 20070701
Effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy: a systematic review. JAMA 20070620
Novel reactions for simple and sensitive spectrophotometric determination of nitrite. Talanta 20070615
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A comparison of sulfadoxine-pyrimethamine with chloroquine and pyrimethamine for prevention of malaria in pregnant Nigerian women. The American journal of tropical medicine and hygiene 20070601
Sensitivity to antifolates and genetic analysis of Plasmodium vivax isolates from Thailand. The American journal of tropical medicine and hygiene 20070601
Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine-pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union. Acta tropica 20070601
Primary school children's perspectives on common diseases and medicines used: implications for school healthcare programmes and priority setting in Uganda. African health sciences 20070601
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Assessing malaria burden during pregnancy in Mali. Acta tropica 20070501
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A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda. Transactions of the Royal Society of Tropical Medicine and Hygiene 20070401
Therapeutic response of multidrug-resistant Plasmodium falciparum and P. vivax to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia. Transactions of the Royal Society of Tropical Medicine and Hygiene 20070401
Efficacy of combined treatment with alpha/beta-arteether and sulfadoxine-pyrimethamine, for cases of Plasmodium falciparum malaria in Jharkhand, India. Annals of tropical medicine and parasitology 20070401
Quality evaluation of chloroquine, quinine, sulfadoxine-pyrimethamine and proguanil formulations sold on the market in East Congo DR. Journal of clinical pharmacy and therapeutics 20070401
Sulfadoxine-pyrimethamine efficacy and selection of Plasmodium falciparum DHFR mutations in Burkina Faso before its introduction as intermittent preventive treatment for pregnant women. The American journal of tropical medicine and hygiene 20070401
Unusual pattern of Plasmodium falciparum drug resistance in the northwestern Peruvian Amazon region. The American journal of tropical medicine and hygiene 20070401
Intermittent preventive treatment of malaria in pregnancy: the effect of new delivery approaches on access and compliance rates in Uganda. Tropical medicine & international health : TM & IH 20070401
Detection of drug resistance markers for chloroquine and pyrimethamine-sulfadoxine in Jazan area, Saudi Arabia using PCR and restriction digestion. Journal of the Egyptian Society of Parasitology 20070401
Health workers perceptions on chloroquine and sulfadoxine/sulfalene pyrimethamine monotherapies: implications for the change to combination therapy of artemether/lumefantrine in Tanzania. East African journal of public health 20070401
Correlations between treatment outcome and both anti-MSP119 antibody response and erythrocyte-related genetic factors in Plasmodium falciparum malaria. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070301
Practical HPLC methods for the quantitative determination of common antimalarials in Africa. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301
Effect of haematinic supplementation and malaria prevention on maternal anaemia and malaria in western Kenya. Tropical medicine & international health : TM & IH 20070301
Thiamin deficiency and uncomplicated falciparum malaria in Laos. Tropical medicine & international health : TM & IH 20070301
The role of communication between clients and health care providers: implications for adherence to malaria treatment in rural Gambia. Tropical medicine & international health : TM & IH 20070301
Sulfadoxine-pyrimethamine susceptibilities and analysis of the dihydrofolate reductase and dihydropteroate synthase of Plasmodium falciparum isolates from Côte d'Ivoire. Annals of tropical medicine and parasitology 20070301
[Assessment of the efficacy of antimalarial drugs in Tarapacá, in the Colombian Amazon basin]. Biomedica : revista del Instituto Nacional de Salud 20070301
Influence of consecutive-day blood sampling on polymerase chain reaction-adjusted parasitological cure rates in an antimalarial-drug trial conducted in Tanzania. The Journal of infectious diseases 20070215
Antimalarial drug combinations in vastly different settings. Lancet (London, England) 20070210
Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial. Lancet (London, England) 20070210
Antischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks. Transactions of the Royal Society of Tropical Medicine and Hygiene 20070201
Amodiaquine combined with sulfadoxine/pyrimethamine versus artemisinin-based combinations for the treatment of uncomplicated falciparum malaria in Africa: a meta-analysis. Transactions of the Royal Society of Tropical Medicine and Hygiene 20070201
From evidence to action? Challenges to policy change and programme delivery for malaria in pregnancy. The Lancet. Infectious diseases 20070201
Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand. The Tohoku journal of experimental medicine 20070201
Sustained use of insecticide-treated curtains is not associated with greater circulation of drug-resistant malaria parasites, or with higher risk of treatment failure among children with uncomplicated malaria in Burkina Faso. The American journal of tropical medicine and hygiene 20070201
Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within 2 weeks after treatment. Tropical medicine & international health : TM & IH 20070201
Subclinical Plasmodium falciparum infection and HIV-1 viral load. Emerging infectious diseases 20070201
Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug quality. Journal of pharmaceutical and biomedical analysis 20070104
Field-based evidence for linkage of mutations associated with chloroquine (pfcrt/pfmdr1) and sulfadoxine-pyrimethamine (pfdhfr/pfdhps) resistance and for the fitness cost of multiple mutations in P. falciparum. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070101
Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use. PloS one 20070101
Molecular surveillance of drug-resistance associated mutations of Plasmodium falciparum in south-west Tanzania. Malaria journal 20070101
Efficacies of artesunate plus either sulfadoxine-pyrimethamine or amodiaquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan. Annals of tropical medicine and parasitology 20070101
Dihydroartemisinin suppository in moderately severe malaria: comparative efficacy of dihydroartemisinin suppository versus intramuscular artemeter followed by oral sulfadoxine-pyrimethamine in the management of moderately severe malaria in Nigerian children. The American journal of tropical medicine and hygiene 20070101
Home-based management of fever in rural Uganda: community perceptions and provider opinions. Malaria journal 20070101
The safety of artemisinins during pregnancy: a pressing question. Malaria journal 20070101
Intermittent preventive treatment for malaria in pregnancy in Africa: what's new, what's needed? Malaria journal 20070101
Medicines informal market in Congo, Burundi and Angola: counterfeit and sub-standard antimalarials. Malaria journal 20070101
Prophylactic trimethoprim-sulfadiazine during chemotherapy in dogs with lymphoma and osteosarcoma: a double-blind, placebo-controlled study. Journal of veterinary internal medicine 20070101
Island-wide diversity in single nucleotide polymorphisms of the Plasmodium vivax dihydrofolate reductase and dihydropteroate synthetase genes in Sri Lanka. Malaria journal 20070101
Artesunate--amodiaquine combination therapy for falciparum malaria in young Gabonese children. Malaria journal 20070101
Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant. Malaria journal 20070101
Diagnosis and treatment of malaria in peripheral health facilities in Uganda: findings from an area of low transmission in south-western Uganda. Malaria journal 20070101
Determination of 10 sulfonamide residues in meat samples by liquid chromatography with ultraviolet detection. Journal of AOAC International 20070101
Efficacy of antimalarial treatment in Guinea: in vivo study of two artemisinin combination therapies in Dabola and molecular markers of resistance to sulphadoxine-pyrimethamine in N'Zérékoré. Malaria journal 20070101
Use of over-the-counter malaria medicines in children and adults in three districts in Kenya: implications for private medicine retailer interventions. Malaria journal 20070101
Paracheck-Pf accuracy and recently treated Plasmodium falciparum infections: is there a risk of over-diagnosis? Malaria journal 20070101
Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar. Malaria journal 20070101
Safety and toxicity of sulfadoxine/pyrimethamine: implications for malaria prevention in pregnancy using intermittent preventive treatment. Drug safety 20070101
Efficacy of chloroquine and sulfadoxine/pyrimethamine mono- and combined therapy against falciparum malaria in Sudan. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20070101
Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal. Malaria journal 20070101
Intermittent preventive treatment with sulphadoxine-pyrimethamine is effective in preventing maternal and placental malaria in Ibadan, south-western Nigeria. Malaria journal 20070101
Estimating antimalarial drugs consumption in Africa before the switch to artemisinin-based combination therapies (ACTs). Malaria journal 20070101
A comparative study on the efficacy of artesunate plus sulphadoxine/pyrimethamine versus artemether-lumefantrine in eastern Sudan. Malaria journal 20070101
Battling the malaria iceberg with chloroquine in India. Malaria journal 20070101
The implication of dihydrofolate reductase and dihydropteroate synthetase gene mutations in modification of Plasmodium falciparum characteristics. Malaria journal 20070101
Malaria prevalence in Nias District, North Sumatra Province, Indonesia. Malaria journal 20070101
CCR5 haplotypes and mother-to-child HIV transmission in Malawi. PloS one 20070101
World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria. Malaria journal 20070101
Malaria pharmacovigilance in Africa: lessons from a pilot project in Mpumalanga Province, South Africa. Drug safety 20070101
[Sulfadoxine-pyrimethamine resistance in Maputo, Mozambique: presence of mutations in the dhfr and dhps genes of Plasmodium falciparum]. Revista da Sociedade Brasileira de Medicina Tropical 20070101
Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications. Malaria journal 20070101
Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate. PloS one 20070101
Decline of placental malaria in southern Ghana after the implementation of intermittent preventive treatment in pregnancy. Malaria journal 20070101
Prevalence of mutations associated with antimalarial drugs in Plasmodium falciparum isolates prior to the introduction of sulphadoxine-pyrimethamine as first-line treatment in Iran. Malaria journal 20070101
A randomized controlled pilot trial of azithromycin or artesunate added to sulfadoxine-pyrimethamine as treatment for malaria in pregnant women. PloS one 20070101
Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum. Malaria journal 20070101
Improving quality of reproductive health care in Senegal through formative supervision: results from four districts. Human resources for health 20070101
Malaria control in Malawi: are the poor being served? International journal for equity in health 20070101
Intermittent preventive treatment for the prevention of malaria during pregnancy in high transmission areas. Malaria journal 20070101
How is childhood development of immunity to Plasmodium falciparum enhanced by certain antimalarial interventions? Malaria journal 20070101
Malaria incidence and efficacy of intermittent preventive treatment in infants (IPTi). Malaria journal 20070101
A randomized open-label trial of artesunate- sulfadoxine-pyrimethamine with or without primaquine for elimination of sub-microscopic P. falciparum parasitaemia and gametocyte carriage in eastern Sudan. PloS one 20070101
Estimated financial and human resources requirements for the treatment of malaria in Malawi. Malaria journal 20070101
Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West Africa. Malaria journal 20070101
Antiplasmodial effects of the aqueous extract of Phyllantus amarus Schumach and Thonn against Plasmodium berghei in Swiss albino mice. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20070101
Sudden enlargement of the prostate in a patient taking Fansidar for malaria. Drug metabolism and drug interactions 20070101
HIV immunosuppression and antimalarial efficacy: sulfadoxine-pyrimethamine for the treatment of uncomplicated malaria in HIV-infected adults in Siaya, Kenya. The Journal of infectious diseases 20061201
Continued efficacy of sulfadoxine-pyrimethamine as second line treatment for malaria in children in Guinea-Bissau. Acta tropica 20061201
Sulfadoxine-pyrimethamine pharmacokinetics in malaria: pediatric dosing implications. Clinical pharmacology and therapeutics 20061201
Rifampicin/Cotrimoxazole/Isoniazid versus mefloquine or quinine + sulfadoxine- pyrimethamine for malaria: a randomized trial. PLoS clinical trials 20061201
A plant-derived morphinan as a novel lead compound active against malaria liver stages. PLoS medicine 20061201
Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children. Memorias do Instituto Oswaldo Cruz 20061201
The influence of genetic innate resistance and acquired immunity on drug treatment outcome of uncomplicated Plasmodium falciparum malaria in Tanzania. Parassitologia 20061201
Malaria. Chloroquine makes a comeback. Science (New York, N.Y.) 20061110
Return of chloroquine antimalarial efficacy in Malawi. The New England journal of medicine 20061109
Rapid selection of dhfr mutant allele in Plasmodium falciparum isolates after the introduction of sulfadoxine/pyrimethamine in combination with 4-aminoquinolines in Papua New Guinea. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20061101
Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali. Transactions of the Royal Society of Tropical Medicine and Hygiene 20061101
A randomised, double-blind, placebo-controlled trial of atovaquone-proguanil vs. sulphadoxine-pyrimethamine in the treatment of malarial anaemia in Zambian children. Tropical medicine & international health : TM & IH 20061101
Improved efficacy with amodiaquine instead of chloroquine in sulfadoxine/pyrimethamine combination treatment of falciparum malaria in Uganda: experience with fixed-dose formulation. Acta tropica 20061101
Amodiaquine, malaria, pregnancy: the old new drug. Lancet (London, England) 20061014
Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial. Lancet (London, England) 20061014
HIV-1 immune suppression and antimalarial treatment outcome in Zambian adults with uncomplicated malaria. The Journal of infectious diseases 20061001
Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes. Tropical medicine & international health : TM & IH 20061001
Malaria control using indoor residual spraying and larvivorous fish: a case study in Betul, central India. Tropical medicine & international health : TM & IH 20061001
Cost-effectiveness study of three antimalarial drug combinations in Tanzania. PLoS medicine 20061001
Responding to AIDS, tuberculosis, malaria, and emerging infectious diseases in Burma: dilemmas of policy and practice. PLoS medicine 20061001
Amino acid mutations in Plasmodium vivax DHFR and DHPS from several geographical regions and susceptibility to antifolate drugs. The American journal of tropical medicine and hygiene 20061001
Use of area under the curve to characterize transmission potential after antimalarial treatment. The American journal of tropical medicine and hygiene 20061001
Therapeutic efficacy of quinine plus sulfadoxine-pyremethamine for the treatment of uncomplicated falciparum malaria in Bangladesh. The American journal of tropical medicine and hygiene 20061001
A randomized controlled trial of folate supplementation when treating malaria in pregnancy with sulfadoxine-pyrimethamine. PLoS clinical trials 20061001
Interaction studies of omeprazole with mefloquine, pyrimethamine and sulfadoxine. Pakistan journal of pharmaceutical sciences 20061001
Treating malaria at home in Uganda. Bulletin of the World Health Organization 20061001
Short course of quinine plus a single dose of sulfadoxine/pyrimethamine for Plasmodium falciparum malaria. Wiener klinische Wochenschrift 20061001
Simultaneous quantification of alpha-/beta-diastereomers of arteether, sulphadoxine and pyrimethamine: a promising anti-relapse antimalarial therapeutic combination, by liquid chromatography tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914
Therapeutic efficacy of chloroquine in Plasmodium vivax from areas with different epidemiological patterns in India and their Pvdhfr gene mutation pattern. Transactions of the Royal Society of Tropical Medicine and Hygiene 20060901
Fixed drug eruption in Nigeria. International journal of dermatology 20060901
Cotrimoxazole prophylaxis and malaria in Africa: Have the important questions been answered? The American journal of tropical medicine and hygiene 20060901
Effect of cotrimoxazole prophylaxis taken by human immunodeficiency virus (HIV)-infected persons on the selection of sulfadoxine-pyrimethamine-resistant malaria parasites among HIV-uninfected household members. The American journal of tropical medicine and hygiene 20060901
Molecular epidemiology of malaria in Cameroon. XXI. Baseline therapeutic efficacy of chloroquine, amodiaquine, and sulfadoxine-pyrimethamine monotherapies in children before national drug policy change. The American journal of tropical medicine and hygiene 20060901
Submicroscopic Plasmodium falciparum infections before and after sulfadoxine-pyrimethamine and artesunate association treatment in Dienga, Southeastern Gabon. Clinical medicine & research 20060901
A simple technique for the detection of anti-malarial drug formulations and their presence in human urine. Tanzania health research bulletin 20060901
Multiresidue determination of sulfonamides in edible catfish, shrimp and salmon tissues by high-performance liquid chromatography with postcolumn derivatization and fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060818
Perceptions on use of sulfadoxine-pyrimethamine in pregnancy and the policy implications for malaria control in Uganda. Health policy (Amsterdam, Netherlands) 20060801
Intermittent preventive treatment in infants--adjusting expectations and seeing opportunity. The Journal of infectious diseases 20060801
Protecting pregnant women from malaria in areas of high HIV infection prevalence. The Journal of infectious diseases 20060801
Intermittent preventive treatment for malaria control administered at the time of routine vaccinations in Mozambican infants: a randomized, placebo-controlled trial. The Journal of infectious diseases 20060801
Randomized trial of 2-dose versus monthly sulfadoxine-pyrimethamine intermittent preventive treatment for malaria in HIV-positive and HIV-negative pregnant women in Malawi. The Journal of infectious diseases 20060801
Malaria prevention during pregnancy: assessing the disease burden one year after implementing a program of intermittent preventive treatment in Koupela District, Burkina Faso. The American journal of tropical medicine and hygiene 20060801
Relationship between antipyretic effects and cytokine levels in uncomplicated falciparum malaria during different treatment regimes. Acta tropica 20060801
Gametocytaemia after drug treatment of asymptomatic Plasmodium falciparum. PLoS clinical trials 20060801
Antifolate resistance in Plasmodium falciparum: multiple origins and identification of novel dhfr alleles. The Journal of infectious diseases 20060715
Artesunate plus sulfadoxine-pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria during pregnancy in eastern Sudan. Transactions of the Royal Society of Tropical Medicine and Hygiene 20060701
Elucidation of sulfadoxine resistance with structural models of the bifunctional Plasmodium falciparum dihydropterin pyrophosphokinase-dihydropteroate synthase. Bioorganic & medicinal chemistry 20060701
Plasmodium falciparum infection dynamics and transmission potential following treatment with sulfadoxine-pyrimethamine. The Journal of antimicrobial chemotherapy 20060701
A randomized, placebo-controlled trial of intermittent preventive treatment with sulphadoxine-pyrimethamine in Gambian multigravidae. Tropical medicine & international health : TM & IH 20060701
Urban malaria in Dakar, Senegal: chemosusceptibility and genetic diversity of Plasmodium falciparum isolates. The American journal of tropical medicine and hygiene 20060701
Short report: molecular markers associated with Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in the Democratic Republic of Congo. The American journal of tropical medicine and hygiene 20060701
Roles of specific Plasmodium falciparum mutations in resistance to amodiaquine and sulfadoxine-pyrimethamine in Burkina Faso. The American journal of tropical medicine and hygiene 20060701
Randomised trial of chloroquine/sulphadoxine-pyrimethamine in Gambian children with malaria: impact against multidrug-resistant P. falciparum. PLoS clinical trials 20060701
[In vivo sensitivity of Plasmodium faciparum to chloroquine and sulfadoxine pyrimethamine in the Bobo Dioulasso region (1998-2001): risk factors associated with treatments failures to the two drugs]. Bulletin de la Societe de pathologie exotique (1990) 20060701
Single-dose sulfadoxine-pyrimethamine in intermittent preventive treatment of malaria. The Journal of infectious diseases 20060601
In vitro study assessing the response of plasmodium falciparum malaria to chloroquine, sulfadoxine/pyrimethamine, quinine and mefloquine in Wad Medani District, Sudan. Saudi medical journal 20060601
Lack of inhibition of the anti-malarial action of sulfadoxine-pyrimethamine by folic acid supplementation when used for intermittent preventive treatment in Gambian primigravidae. The American journal of tropical medicine and hygiene 20060601
Folic acid treatment of Zambian children with moderate to severe malaria anemia. The American journal of tropical medicine and hygiene 20060601
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for uncomplicated malaria: a systematic review. Tropical medicine & international health : TM & IH 20060601
Impact of chloroquine on viral load in breast milk. Tropical medicine & international health : TM & IH 20060601
A systematic map of genetic variation in Plasmodium falciparum. PLoS pathogens 20060601
[Knowledge and practice among health workers from the Thiès region with regard to new malaria treatment policies]. Sante publique (Vandoeuvre-les-Nancy, France) 20060601
Pharmacokinetic interactions between chloroquine, sulfadoxine and pyrimethamine and their bioequivalence in a generic fixed-dose combination in healthy volunteers in Uganda. African health sciences 20060601
Efficacy of chloroquine, sulfadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria among children under five in Bongor and Koumra, Chad. Transactions of the Royal Society of Tropical Medicine and Hygiene 20060501
Potential impact of intermittent preventive treatment (IPT) on spread of drug-resistant malaria. PLoS medicine 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Comparative efficacy of chloroquine and sulphadoxine--pyrimethamine in pregnant women and children: a meta-analysis. Tropical medicine & international health : TM & IH 20060501
Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults. Tropical medicine & international health : TM & IH 20060501
The efficacy of sulfadoxine-pyrimethamine alone and in combination with chloroquine for malaria treatment in rural Eastern Sudan: the interrelation between resistance, age and gametocytogenesis. Tropical medicine & international health : TM & IH 20060501
Sulfadoxine-pyrimethamine as an anti-malaria preventative in donated blood. The American journal of tropical medicine and hygiene 20060501
Severe cutaneous reactions to sulfadoxine-pyrimethamine and trimethoprim-sulfamethoxazole in Blantyre District, Malawi. The American journal of tropical medicine and hygiene 20060501
Short report: Dynamics of Plasmodium falciparum malaria after sub-optimal therapy in Uganda. The American journal of tropical medicine and hygiene 20060501
(Sub)microscopic Plasmodium falciparum gametocytaemia in Kenyan children after treatment with sulphadoxine-pyrimethamine monotherapy or in combination with artesunate. International journal for parasitology 20060401
Predictors of the failure of treatment with pyrimethamine-sulfadoxine in children with uncomplicated falciparum malaria. Acta tropica 20060401
Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistance. The Journal of infectious diseases 20060401
Reaching the Abuja target for intermittent preventive treatment of malaria in pregnancy in African women: a review of progress and operational challenges. Tropical medicine & international health : TM & IH 20060401
Microscopy and outpatient malaria case management among older children and adults in Kenya. Tropical medicine & international health : TM & IH 20060401
Prevalence of malaria parasitemia among clients seeking treatment for fever or malaria at drug stores in rural Tanzania 2004. Tropical medicine & international health : TM & IH 20060401
The costs of changing national policy: lessons from malaria treatment policy guidelines in Tanzania. Tropical medicine & international health : TM & IH 20060401
Prevention of malaria during pregnancy in West Africa: policy change and the power of subregional action. Tropical medicine & international health : TM & IH 20060401
Polymerase chain reaction and molecular genotyping to monitor parasitological response to anti-malarial chemotherapy in the Peruvian Amazon. The American journal of tropical medicine and hygiene 20060401
Existence of antimalarial formulations with low bioavailability in Tanzania. Tropical doctor 20060401
Central nervous system toxoplasmosis in adult Ethiopians. Ethiopian medical journal 20060401
Therapeutic efficacy of sulfadoxin/pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria in Enseno, Meskan Woreda, Gurage zone, SNNPR, Ethiopia. Ethiopian medical journal 20060401
Efficacy of sulfadoxine-pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria in East Timor. The American journal of tropical medicine and hygiene 20060301
Chemoprophylaxis and malaria death rates. Emerging infectious diseases 20060301
[Coartem and fansimef in the treatment of falciparum malaria]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20060227
Seasonal intermittent preventive treatment with artesunate and sulfadoxine-pyrimethamine for prevention of malaria in Senegalese children: a randomised, placebo-controlled, double-blind trial. Lancet (London, England) 20060225
Increased density but not prevalence of gametocytes following drug treatment of Plasmodium falciparum. Transactions of the Royal Society of Tropical Medicine and Hygiene 20060201
A randomized trial comparing the efficacy of four treatment regimens for uncomplicated falciparum malaria in Assam state, India. Transactions of the Royal Society of Tropical Medicine and Hygiene 20060201
Point mutations in the dihydrofolate reductase and dihydropteroate synthase genes of Plasmodium falciparum and resistance to sulfadoxine-pyrimethamine in Sri Lanka. The American journal of tropical medicine and hygiene 20060201
Frequency distribution of antimalarial drug-resistant alleles among isolates of Plasmodium falciparum in Bangui, Central African Republic. The American journal of tropical medicine and hygiene 20060201
Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria. The Cochrane database of systematic reviews 20060125
Ocular manifestations in congenital toxoplasmosis. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060101
How sulfadoxine-pyrimethamine (SP) was perceived in some rural communities after phasing out chloroquine (CQ) as a first-line drug for uncomplicated malaria in Tanzania: lessons to learn towards moving from monotherapy to fixed combination therapy. Journal of ethnobiology and ethnomedicine 20060101
CD4 T cell activation as a predictor for treatment failure in Ugandans with Plasmodium falciparum malaria. The American journal of tropical medicine and hygiene 20060101
The efficacies of artesunate-sulfadoxine-pyrimethamine and artemether-lumefantrine in the treatment of uncomplicated, Plasmodium falciparum malaria, in an area of low transmission in central Sudan. Annals of tropical medicine and parasitology 20060101
Therapeutic efficacy test in malaria falciparum in Antioquia, Colombia. Malaria journal 20060101
A steep decline of malaria morbidity and mortality trends in Eritrea between 2000 and 2004: the effect of combination of control methods. Malaria journal 20060101
Adherence of community caretakers of children to pre-packaged antimalarial medicines (HOMAPAK) among internally displaced people in Gulu district, Uganda. Malaria journal 20060101
Artemether-lumefantrine versus artesunate plus amodiaquine for treating uncomplicated childhood malaria in Nigeria: randomized controlled trial. Malaria journal 20060101
Therapeutic efficacy of sulphadoxine-pyrimethamine and chloroquine for the treatment of uncomplicated malaria in pregnancy in Burkina Faso. Malaria journal 20060101
High prevalence of drug-resistance mutations in Plasmodium falciparum and Plasmodium vivax in southern Ethiopia. Malaria journal 20060101
From chloroquine to artemisinin-based combination therapy: the Sudanese experience. Malaria journal 20060101
Safety and efficacy of lumefantrine-artemether (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Zambian adults. Malaria journal 20060101
A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan. Annals of clinical microbiology and antimicrobials 20060101
Dynamics of immune response and drug resistance in malaria infection. Malaria journal 20060101
Drug resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum malaria in Mlimba, Tanzania. Malaria journal 20060101
An in-depth study of patent medicine sellers' perspectives on malaria in a rural Nigerian community. Malaria journal 20060101
Combined chloroquine, sulfadoxine/pyrimethamine and primaquine against Plasmodium falciparum in Central Java, Indonesia. Malaria journal 20060101
Decreased availability of antimalarials in the private sector following the policy change from chloroquine to sulphadoxine-pyrimethamine in the Kilombero Valley, Tanzania. Malaria journal 20060101
Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space? Malaria journal 20060101
Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo. Malaria journal 20060101
[In vitro antimalarial drug resistance in Southeastern Bangladesh]. Wiener klinische Wochenschrift 20060101
Consumers stated and revealed preferences for community health workers and other strategies for the provision of timely and appropriate treatment of malaria in southeast Nigeria. Malaria journal 20060101
[Opportunistic infections in HIV-infected subjects: no wonders]. Terapevticheskii arkhiv 20060101
Effect of Aristolochia petersiana on the efficacy of fansidar. The Central African journal of medicine 20060101
[Prenatal treatment of congenital toxoplasmosis]. Presse medicale (Paris, France : 1983) 20051217
Infectious diseases. Will a preemptive strike against malaria pay off? Science (New York, N.Y.) 20051209
Rare Congolese Plasmodium falciparum DHFR alleles. Molecular and biochemical parasitology 20051201
Intermittent preventive treatment for malaria in infants: moving forward, cautiously. The Journal of infectious diseases 20051201
Parasitological rebound effect and emergence of pyrimethamine resistance in Plasmodium falciparum after single-dose sulfadoxine-pyrimethamine. The Journal of infectious diseases 20051201
The quality of sulphadoxine-pyrimethamine and amodiaquine products in the Kenyan retail sector. Journal of clinical pharmacy and therapeutics 20051201
The chemical and pharmaceutical equivalence of sulphadoxine/pyrimethamine tablets sold on the Tanzanian market. Journal of clinical pharmacy and therapeutics 20051201
In vitro processing of donor blood with sulfadoxine-pyrimethamine for eradication of transfusion-induced malaria. The American journal of tropical medicine and hygiene 20051201
Molecular surveillance of mutations in dihydrofolate reductase and dihydropteroate synthase genes of Plasmodium falciparum in Ethiopia. The American journal of tropical medicine and hygiene 20051201
Amplification of Plasmodium falciparum multidrug resistance gene 1 in isolates from Gabon. The Journal of infectious diseases 20051115
Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa. PLoS medicine 20051101
Use of intermittent preventive treatment for malaria in pregnancy in a rural area of western Kenya with high coverage of insecticide-treated bed nets. Tropical medicine & international health : TM & IH 20051101
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children. Tropical medicine & international health : TM & IH 20051101
Amodiaquine and combination chemotherapy for malaria. The American journal of tropical medicine and hygiene 20051101
Amodiaquine, sulfadoxine-pyrimethamine, and combination therapy for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso. The American journal of tropical medicine and hygiene 20051101
Prevalence of Plasmodium falciparum mutations associated with antimalarial drug resistance during an epidemic in Kuna Yala, Panama, Central America. The American journal of tropical medicine and hygiene 20051101
Determination of pKa values by capillary zone electrophoresis with a dynamic coating procedure. Journal of separation science 20051101
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria. The Cochrane database of systematic reviews 20051019
Malaria cure with sulphadoxine/pyrimethamine combination in 12 semi-immune adults from West-Central Africa with high rates of point mutations in Plasmodium falciparum dhfr and dhps genes. Parasitology research 20051001
Efficacy of chloroquine + sulfadoxine--pyrimethamine, mefloquine + artesunate and artemether + lumefantrine combination therapies to treat Plasmodium falciparum malaria in the Chittagong Hill Tracts, Bangladesh. Transactions of the Royal Society of Tropical Medicine and Hygiene 20051001
Epidemiology of drug-resistant malaria in Republic of Congo: using molecular evidence for monitoring antimalarial drug resistance combined with assessment of antimalarial drug use. Tropical medicine & international health : TM & IH 20051001
Adoption of the new antimalarial drug policy in Tanzania--a cross-sectional study in the community. Tropical medicine & international health : TM & IH 20051001
Cluster randomised trial of intermittent preventive treatment for malaria in infants in area of high, seasonal transmission in Ghana. BMJ (Clinical research ed.) 20051001
Treatment of paediatric malaria during a period of drug transition to artemether-lumefantrine in Zambia: cross sectional study. BMJ (Clinical research ed.) 20051001
Therapeutic efficacy of sulfadoxine-pyrimethamine and amodiaquine among children with uncomplicated Plasmodium falciparum malaria in Zanzibar, Tanzania. The American journal of tropical medicine and hygiene 20051001
Reduced variation around drug-resistant dhfr alleles in African Plasmodium falciparum. Molecular biology and evolution 20050901
Rapid increase in resistance of Plasmodium falciparum to chloroquine-Fansidar in Uganda and the potential of amodiaquine-Fansidar as a better alternative. Acta tropica 20050901
Polymorphisms in Plasmodium falciparum dhfr and dhps genes and age related in vivo sulfadoxine-pyrimethamine resistance in malaria-infected patients from Nigeria. Acta tropica 20050901
Comparative efficacy of antimalarial drugs including ACTs in the treatment of uncomplicated malaria among children under 5 years in Ghana. Acta tropica 20050901
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