Home Sulfos Benzamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-, hydrochloride (1:1)

Benzamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-, hydrochloride (1:1)

CAS No.:
23694-17-9
Catalog Number:
AG002O5N
Molecular Formula:
C17H27ClN2O4S
Molecular Weight:
390.9253
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$223
- +
10mg
99%
1 week
United States
$348
- +
25mg
99%
1 week
United States
$640
- +
50mg
99%
1 week
United States
$1029
- +
Product Description
Catalog Number:
AG002O5N
Chemical Name:
Benzamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-, hydrochloride (1:1)
CAS Number:
23694-17-9
Molecular Formula:
C17H27ClN2O4S
Molecular Weight:
390.9253
MDL Number:
MFCD01319147
IUPAC Name:
N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride
InChI:
InChI=1S/C17H26N2O4S.ClH/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3;/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20);1H
InChI Key:
IGOWMQPOGQYFFM-UHFFFAOYSA-N
SMILES:
CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC.Cl
Properties
Complexity:
517  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
390.138g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
390.923g/mol
Monoisotopic Mass:
390.138g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
84.1A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Effect of the antipsychotic agent amisulpride on glucose lowering and insulin secretion. Diabetes, obesity & metabolism 20120401
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No negative symptoms in healthy volunteers after single doses of amisulpride, aripiprazole, and haloperidol: a double-blind placebo-controlled trial. International clinical psychopharmacology 20120301
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Prediction of torsade de pointes from the QT interval: analysis of a case series of amisulpride overdoses. Clinical pharmacology and therapeutics 20110801
Clozapine-induced salivation: interaction with N-desmethylclozapine and amisulpride in an experimental rat model. European journal of oral sciences 20110801
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Amisulpride overdose is frequently associated with QT prolongation and torsades de pointes. Journal of clinical psychopharmacology 20100801
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Amisulpride overdose: suggested management of prolonged QTc. Emergency medicine journal : EMJ 20100701
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Inhibitory effects of polyphenol compounds on lipid peroxidation caused by antipsychotics (haloperidol and amisulpride) in human plasma in vitro. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20100301
Acute rhabdomyolysis during treatment with amisulpride and metformin. European journal of clinical pharmacology 20100301
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Clozapine and amisulpride in refractory schizophrenia and alcohol dependence. Journal of clinical psychopharmacology 20071001
Increase in plasma concentration of amisulpride after addition of concomitant lithium. Journal of clinical psychopharmacology 20071001
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Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics. Journal of psychopharmacology (Oxford, England) 20070901
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Comparative validation of amisulpride determination in pharmaceuticals by several chromatographic, electrophoretic and spectrophotometric methods. Analytica chimica acta 20070508
Blockade of morphine-induced behavioral sensitization by a combination of amisulpride and RB101, comparison with classical opioid maintenance treatments. British journal of pharmacology 20070501
Amisulpride in the short-term treatment of depressive and physical symptoms in cancer patients during chemotherapies. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070501
Metabolic control in patients with schizophrenia treated with amisulpride or olanzapine. International clinical psychopharmacology 20070501
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Atypical antipsychotic therapy for treatment of schizophrenia in Hong Kong Chinese patients--a cost analysis. International journal of clinical pharmacology and therapeutics 20070501
Amenorrhea after sertraline introduction in an amisulpride-treated patient with undiagnosed polycystic ovary disease. Journal of clinical psychopharmacology 20070401
Development of tardive dyskinesia in a patient taking amisulpride. Progress in neuro-psychopharmacology & biological psychiatry 20070330
[The benzamides tiapride, sulpiride, and amisulpride in treatment for Tourette's syndrome]. Der Nervenarzt 20070301
Amisulpride-induced hyperprolactinaemia is not reversed by addition of aripiprazole. The international journal of neuropsychopharmacology 20070201
Transient hyperglycemia and decreased glucose tolerance during antipsychotic monotherapy with amisulpride. Journal of clinical psychopharmacology 20070201
Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride. Acta psychiatrica Scandinavica 20070201
Amisulpride augmentation after the failure of citalopram for depression: a case report. Journal of clinical pharmacy and therapeutics 20070201
Amisulpride-induced hyperprolactinemia is reversible following discontinuation. Progress in neuro-psychopharmacology & biological psychiatry 20070130
Is the superior efficacy of new generation antipsychotics an artifact of LOCF? Schizophrenia bulletin 20070101
Atypical antipsychotics and pituitary neoplasms in the WHO database. Psychopharmacology bulletin 20070101
Outcomes in schizophrenia outpatients treated with amisulpride or olanzapine. Pharmacopsychiatry 20070101
Comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study. Advances in therapy 20070101
Atypical antipsychotic drugs in the treatment of delusional parasitosis. International journal of psychiatry in medicine 20070101
[Delusional bromosis: treatment with amisulpiride and olanzapine]. Annales de dermatologie et de venereologie 20070101
Neuroleptic malignant syndrome due to amisulpride in a patient with solvent-induced chronic toxic encephalopathy. Clinical neuropharmacology 20070101
Amisulpride-induced neuroleptic malignant syndrome. The Journal of neuropsychiatry and clinical neurosciences 20070101
Amisulpride-induced tardive dyskinesia. Schizophrenia research 20061201
Efficacy of amisulpride in treating primary negative symptoms in first-episode psychosis: a pilot study. Human psychopharmacology 20061201
Remission and relapse in the outpatient care of schizophrenia: three-year results from the Schizophrenia Outpatient Health Outcomes study. Journal of clinical psychopharmacology 20061201
A double-blind randomised comparative trial of amisulpride versus olanzapine for 2 months in the treatment of subjects with schizophrenia and comorbid depression. European psychiatry : the journal of the Association of European Psychiatrists 20061201
[The use of atypical antipsychotics in the long-term care of schizophrenia]. L'Encephale 20061201
Improvement of patient compliance after switching from conventional neuroleptics to the atypical neuroleptic amisulpride. Journal of psychopharmacology (Oxford, England) 20061101
Early changes of plasma lipids during treatment with atypical antipsychotics. International clinical psychopharmacology 20061101
The treatment of negative symptoms and deficit states of chronic schizophrenia: olanzapine compared to amisulpride and placebo in a 6-month double-blind controlled clinical trial. Acta psychiatrica Scandinavica 20061101
The antipsychotic sultopride is overdosed--a PET study of drug-induced receptor occupancy in comparison with sulpiride. The international journal of neuropsychopharmacology 20061001
Comparison of pramipexole and amisulpride on alertness, autonomic and endocrine functions in healthy volunteers. Psychopharmacology 20060901
Amisulpride in the treatment of behavioural disturbances among patients with moderate to severe Alzheimer's disease. Acta neurologica Scandinavica 20060801
Blockade of cue-induced brain activation of abstinent alcoholics by a single administration of amisulpride as measured with fMRI. Alcoholism, clinical and experimental research 20060801
Haloperidol alone or in combination for acute mania. The Cochrane database of systematic reviews 20060719
Cyclosporine A (CsA) affects the pharmacodynamics and pharmacokinetics of the atypical antipsychotic amisulpride probably via inhibition of P-glycoprotein (P-gp). Journal of neural transmission (Vienna, Austria : 1996) 20060701
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Effects of novel antipsychotics, amisulpiride and aripiprazole, on maternal behavior in rats. Psychopharmacology 20050901
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Hyperprolactinemia after low dose of amisulpride. Neuro endocrinology letters 20041201
High striatal occupancy of D2-like dopamine receptors by amisulpride in the brain of patients with schizophrenia. The international journal of neuropsychopharmacology 20041201
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Successful treatment of Tourette's disorder with amisulpride. The Annals of pharmacotherapy 20040501
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Combined use of amisulpride and clozapine for patients with treatment-resistant schizophrenia. Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20040301
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THE LESSA (Lebanese Short-term Study with Amisulpride) STUDY a Phase IV clinical trial in acutely ill schizophrenic patients. Le Journal medical libanais. The Lebanese medical journal 20040101
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The antinociceptive effect of amisulpride in mice is mediated through opioid mechanisms. European journal of pharmacology 20031008
Visual and auditory hallucinations with excessive intake of paroxetine. Psychiatry and clinical neurosciences 20031001
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Lack of effect of amisulpride on the pharmacokinetics and safety of lithium. The international journal of neuropsychopharmacology 20030601
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Automated determination of amisulpride by liquid chromatography with column switching and spectrophotometric detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030205
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[Frontal dysfunctions in Huntington's disease -- neuropsychology and therapy]. Psychiatrische Praxis 20030101
Amisulpride versus risperidone in the treatment of schizophrenic patients: a double-blind pilot study in Taiwan. Journal of the Formosan Medical Association = Taiwan yi zhi 20030101
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Effects of amisulpride on consummatory negative contrast. Behavioural pharmacology 20021201
Foreword. The clinical aspects of deficit in dopaminergic ways. International clinical psychopharmacology 20021201
Dopaminergic deficit and the role of amisulpride in the treatment of mood disorders. International clinical psychopharmacology 20021201
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Discriminative stimulus properties in rats of the novel antipsychotic quetiapine. Experimental and clinical psychopharmacology 20021101
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Catatonia and transcranial magnetic stimulation. The American journal of psychiatry 20021001
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A comparison of paroxetine and amisulpride in the treatment of dysthymic disorder. Journal of affective disorders 20020801
Effect of the amisulpride isomers on rat prolactinemia. European journal of pharmacology 20020719
Carmoxirole is able to reduce amisulpride-induced hyperprolactinemia without affecting its central effect. European journal of pharmacology 20020628
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Switching to amisulpride due to hepatic complications. European psychiatry : the journal of the Association of European Psychiatrists 20020501
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Sub-chronic treatment with classical but not atypical antipsychotics produces morphological changes in rat nigro-striatal dopaminergic neurons directly related to 'early onset' vacuous chewing. The European journal of neuroscience 20020401
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Comparative efficacy of SSRIs and amisulpride in burning mouth syndrome: a single-blind study. The Journal of clinical psychiatry 20020101
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(-)S amisulpride binds with high affinity to cloned dopamine D(3) and D(2) receptors. European journal of pharmacology 20011207
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Faster response on amisulpride 50 mg versus sertraline 50-100 mg in patients with dysthymia or double depression: a randomized, double-blind, parallel group study. International clinical psychopharmacology 20011101
Asymptomatic bradycardia associated with amisulpride. Pharmacopsychiatry 20011101
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Physostigmine as treatment for severe CNS anticholinergic toxicity. Emergency medicine journal : EMJ 20010901
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Establishment of enzyme immunoassay for measuring serum sultopride levels. Therapeutic drug monitoring 20010601
In vivo extrastriatal and striatal D2 dopamine receptor blockade by amisulpride in schizophrenia. Journal of clinical psychopharmacology 20010401
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The changes of biological markers and treatment efficacy in schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry 20010201
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