4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
| Title | Journal |
|---|---|
| DNMT1 controls LncRNA H19/ERK signal pathway in hepatic stellate cell activation and fibrosis. | Toxicology letters 20181001 |
| Aristolochic acid I interferes with the expression of BLCAP tumor suppressor gene in human cells. | Toxicology letters 20180701 |
| Modulations of DNMT1 and HDAC1 are involved in the OTA-induced cytotoxicity and apoptosis in vitro. | Chemico-biological interactions 20171225 |
| Multiple drug transporters mediate the placental transport of sulpiride. | Archives of toxicology 20171201 |
| Continuous soy isoflavones exposure from weaning to maturity induces downregulation of ovarian steroidogenic factor 1 gene expression and corresponding changes in DNA methylation pattern. | Toxicology letters 20171105 |
| Aberrant methylation of RUNX3 is present in Aflatoxin B(1)-induced transformation of the L02R cell line. | Toxicology 20170615 |
| Cadmium-induced malignant transformation of rat liver cells: Potential key role and regulatory mechanism of altered apolipoprotein E expression in enhanced invasiveness. | Toxicology 20170501 |
| In vitro analysis of factors influencing CYP1A2 expression as potential determinants of interindividual variation. | Pharmacology research & perspectives 20170401 |
| The Role of miR-182-5p in Hepatocarcinogenesis of Trichloroethylene in Mice. | Toxicological sciences : an official journal of the Society of Toxicology 20170301 |
| Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells. | Oncotarget 20170214 |
| The Inhibitory Role of α2,6-Sialylation in Adipogenesis. | The Journal of biological chemistry 20170210 |
| Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis. | Toxicology and applied pharmacology 20170115 |
| Determinants of orofacial clefting I: Effects of 5-Aza-2'-deoxycytidine on cellular processes and gene expression during development of the first branchial arch. | Reproductive toxicology (Elmsford, N.Y.) 20170101 |
| Determinants of orofacial clefting II: Effects of 5-Aza-2'-deoxycytidine on gene methylation during development of the first branchial arch. | Reproductive toxicology (Elmsford, N.Y.) 20170101 |
| Long-term exposure to estrogen enhances chemotherapeutic efficacy potentially through epigenetic mechanism in human breast cancer cells. | PloS one 20170101 |
| The Synergistic Effects of Decitabine Combined with Arsenic Trioxide (ATO) in the Human Myelodysplastic Syndrome Cell Line SKM-1. | Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 20161201 |
| Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer. | Chemico-biological interactions 20161025 |
| LINE-1 gene hypomethylation and p16 gene hypermethylation in HepG2 cells induced by low-dose and long-term triclosan exposure: The role of hydroxyl group. | Toxicology in vitro : an international journal published in association with BIBRA 20160801 |
| MeCP2 silencing of LncRNA H19 controls hepatic stellate cell proliferation by targeting IGF1R. | Toxicology 20160601 |
| Chromatin remodeling by curcumin alters endogenous aryl hydrocarbon receptor signaling. | Chemico-biological interactions 20160525 |
| Epigenetics Reactivation of Nrf2 in Prostate TRAMP C1 Cells by Curcumin Analogue FN1. | Chemical research in toxicology 20160418 |
| MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. | Oncotarget 20160322 |
| DNA Hypermethylation of CREB3L1 and Bcl-2 Associated with the Mitochondrial-Mediated Apoptosis via PI3K/Akt Pathway in Human BEAS-2B Cells Exposure to Silica Nanoparticles. | PloS one 20160101 |
| Transient resistance to DNA damaging agents is associated with expression of microRNAs-135b and -196b in human leukemia cell lines. | International journal of biochemistry and molecular biology 20160101 |
| Roles of oxidative stress and the ERK1/2, PTEN and p70S6K signaling pathways in arsenite-induced autophagy. | Toxicology letters 20151215 |
| Function of DNA methyltransferase 3a in lead (Pb(2+) )-Induced Cyclooxygenase-2 gene. | Environmental toxicology 20150901 |
| SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer. | Oncogene 20150813 |
| Differential DNA methylation profile of key genes in malignant prostate epithelial cells transformed by inorganic arsenic or cadmium. | Toxicology and applied pharmacology 20150801 |
| Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells. | Chemical research in toxicology 20150518 |
| Epigenetic marks responsible for cadmium-induced melanoma cell overgrowth. | Toxicology in vitro : an international journal published in association with BIBRA 20150201 |
| Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer. | Neoplasia (New York, N.Y.) 20141201 |
| Reversible epigenetic regulation of 14-3-3σ expression in acquired gemcitabine resistance by uhrf1 and DNA methyltransferase 1. | Molecular pharmacology 20141101 |
| Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis. | Toxicology and applied pharmacology 20140915 |
| DNMT3A silencing RASSF1A promotes cardiac fibrosis through upregulation of ERK1/2. | Toxicology 20140902 |
| Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation. | Archives of toxicology 20140801 |
| Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126). | International journal of molecular sciences 20140801 |
| Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1. | Cell reports 20140724 |
| The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB. | Toxicology letters 20140605 |
| Epigenetic silencing of Na,K-ATPase β 1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma. | Epigenetics 20140401 |
| [Effect of arsenic trioxide and 5-aza-2'-deoxycytidine on SHP-1, JAK3, TYK2 gene expression in K562 cells]. | Zhongguo shi yan xue ye xue za zhi 20140401 |
| SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages. | Toxicology letters 20140321 |
| Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer. | International journal of cancer 20140315 |
| Repression of Smad7 mediated by DNMT1 determines hepatic stellate cell activation and liver fibrosis in rats. | Toxicology letters 20140113 |
| Methylation and miRNA effects of resveratrol on mammary tumors vs. normal tissue. | Nutrition and cancer 20140101 |
| Epigenetic regulation of sox30 is associated with testis development in mice. | PloS one 20140101 |
| Hypermethylation of Cox5a promoter is associated with mitochondrial dysfunction in skeletal muscle of high fat diet-induced insulin resistant rats. | PloS one 20140101 |
| Trichloroethylene-induced gene expression and DNA methylation changes in B6C3F1 mouse liver. | PloS one 20140101 |
| Changes in DNA methylation of erythroid-specific genes in K562 cells exposed to phenol and hydroquinone. | Toxicology 20131004 |
| Epigenetic regulation is a crucial factor in the repression of UGT1A1 expression in the human kidney. | Drug metabolism and disposition: the biological fate of chemicals 20131001 |
| Persistent overexpression of DNA methyltransferase 1 attenuating GABAergic inhibition in basolateral amygdala accounts for anxiety in rat offspring exposed perinatally to low-dose bisphenol A. | Journal of psychiatric research 20131001 |
| Inhibition of DNA methylation attenuates low-dose cadmium-induced cardiac contractile and intracellular Ca(2+) anomalies. | Clinical and experimental pharmacology & physiology 20131001 |
| Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis. | Cell death & disease 20130901 |
| Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1. | The Journal of biological chemistry 20130816 |
| Expression of WWOX and FHIT is downregulated by exposure to arsenite in human uroepithelial cells. | Toxicology letters 20130704 |
| 5-Aza-2'-deoxycytidine inhibited PDGF-induced rat airway smooth muscle cell phenotypic switching. | Archives of toxicology 20130501 |
| Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter. | Proceedings of the National Academy of Sciences of the United States of America 20130312 |
| A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons. | CNS neuroscience & therapeutics 20130301 |
| MicroRNA-152 targets DNA methyltransferase 1 in NiS-transformed cells via a feedback mechanism. | Carcinogenesis 20130201 |
| Epigenetic therapies in MDS and AML. | Advances in experimental medicine and biology 20130101 |
| Transporter gene expression in human head and neck squamous cell carcinoma and associated epigenetic regulatory mechanisms. | The American journal of pathology 20130101 |
| Increased PRAME-specific CTL killing of acute myeloid leukemia cells by either a novel histone deacetylase inhibitor chidamide alone or combined treatment with decitabine. | PloS one 20130101 |
| 5-aza-CdR induces the demethylation of Syk promoter in nasopharyngeal carcinoma cell. | Gene 20121215 |
| Differential expression of miRNAs in rhabdomyosarcoma and malignant rhabdoid tumor. | Experimental cell research 20121210 |
| MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer. | Medical oncology (Northwood, London, England) 20121201 |
| Screening of drugs to counteract human papillomavirus 16 E6 repression of E-cadherin expression. | Investigational new drugs 20121201 |
| Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent. | The Prostate 20121201 |
| Hypoxia-inducible factor-1α expression indicates poor prognosis in myelodysplastic syndromes. | Leukemia & lymphoma 20121201 |
| Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor. | International journal of molecular medicine 20121201 |
| Protocadherin8 is a functional tumor suppressor frequently inactivated by promoter methylation in nasopharyngeal carcinoma. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20121101 |
| Refractory anemia with ring sideroblasts associated with marked thrombocytosis harboring cytogenetic abnormality dup(2)(p15p22) treated with decitabine. | Leukemia & lymphoma 20121101 |
| Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma. | Biochimie 20121101 |
| Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors. | Hepatology (Baltimore, Md.) 20121101 |
| PROX1 overexpression inhibits protein kinase C beta II transcription through promoter DNA methylation. | Genes, chromosomes & cancer 20121101 |
| Synergism between clofarabine and decitabine through p53R2: a pharmacodynamic drug-drug interaction modeling. | Leukemia research 20121101 |
| Could decitabine treatment impair memory functions in humans? | Medical hypotheses 20121101 |
| Inhibition of SOX17 by microRNA 141 and methylation activates the WNT signaling pathway in esophageal cancer. | The Journal of molecular diagnostics : JMD 20121101 |
| Epigenetic mechanisms regulate the prostaglandin E receptor 2 in breast cancer. | The Journal of steroid biochemistry and molecular biology 20121101 |
| Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer. | Oncology reports 20121101 |
| DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences. | Expert opinion on drug discovery 20121101 |
| Anti-HIV-1 activity of resveratrol derivatives and synergistic inhibition of HIV-1 by the combination of resveratrol and decitabine. | Bioorganic & medicinal chemistry letters 20121101 |
| Analysis of possible mechanisms accounting for raf-1 kinase inhibitor protein downregulation in hepatocellular carcinoma. | Omics : a journal of integrative biology 20121101 |
| Superinduction of leptin mRNA in mouse hypothalamic neurons. | Neuroreport 20121024 |
| Methylation subtypes and large-scale epigenetic alterations in gastric cancer. | Science translational medicine 20121017 |
| Epigenetically mediated downregulation of the differentiation-promoting chaperon protein CRABP2 in astrocytic gliomas. | International journal of cancer 20121015 |
| DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung. | International journal of cancer 20121001 |
| Sequence-specific biosensors report drug-induced changes in epigenetic silencing in living cells. | DNA and cell biology 20121001 |
| Over-expression of RPL23 in myelodysplastic syndromes is associated with apoptosis resistance of CD34+ cells and predicts poor prognosis and distinct response to CHG chemotherapy or decitabine. | Annals of hematology 20121001 |
| Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. | Experimental hematology 20121001 |
| Comprehensive DNA methylation analysis of benign and malignant adrenocortical tumors. | Genes, chromosomes & cancer 20121001 |
| IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer. | Carcinogenesis 20121001 |
| 14-3-3σ mediates G2-M arrest produced by 5-aza-2'-deoxycytidine and possesses a tumor suppressor role in endometrial carcinoma cells. | Gynecologic oncology 20121001 |
| Phase I/II study of decitabine in patients with myelodysplastic syndrome: a multi-center study in Japan. | Cancer science 20121001 |
| Enforced expression of RASAL1 suppresses cell proliferation and the transformation ability of gastric cancer cells. | Oncology reports 20121001 |
| Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers. | Molecular cancer therapeutics 20121001 |
| DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats. | Toxicology and applied pharmacology 20121001 |
| Increased cleavage rate of human nuclear transfer embryos after 5-aza-2'-deoxycytidine treatment. | Reproductive biomedicine online 20121001 |
| CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. | Cancer biology & therapy 20121001 |
| Promoter methylation of tumor-related genes in gastric carcinogenesis. | Histology and histopathology 20121001 |
| Epigenetic regulation of Wnt signaling pathway gene SRY-related HMG-box 17 in papillary thyroid carcinoma. | Chinese medical journal 20121001 |
| Decitabine, a DNA methyltransferase inhibitor, reduces P-glycoprotein mRNA and protein expressions and increases drug sensitivity in drug-resistant MOLT4 and Jurkat cell lines. | Anticancer research 20121001 |
| Clinical results with the DNA hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in patients with myelodysplastic syndromes: an update. | Seminars in hematology 20121001 |
| [Methylation of FHIT gene promoter region in DNA from plasma of patients with myelodysplastic syndromes and demethylating effect of decitabine]. | Zhongguo shi yan xue ye xue za zhi 20121001 |
| Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications. | British journal of cancer 20120925 |
| Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia. | Blood 20120920 |
| Clofarabine plus low-dose cytarabine followed by clofarabine plus low-dose cytarabine alternating with decitabine in acute myeloid leukemia frontline therapy for older patients. | Cancer 20120915 |
| Global identification of genes regulated by estrogen signaling and demethylation in MCF-7 breast cancer cells. | Biochemical and biophysical research communications 20120914 |
| Development of a novel microRNA promoter microarray for ChIP-on-chip assay to identify epigenetically regulated microRNAs. | Biochemical and biophysical research communications 20120914 |
| Epigenetic modulation of the biophysical properties of drug-resistant cell lipids to restore drug transport and endocytic functions. | Molecular pharmaceutics 20120904 |
| Clonal cytogenetic abnormalities after tyrosine kinase inhibitor therapy in Ph+ ALL resolution after decitabine therapy. | Pediatric blood & cancer 20120901 |
| A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20120901 |
| Differential effects of low-dose decitabine on immune effector and suppressor responses in melanoma-bearing mice. | Cancer immunology, immunotherapy : CII 20120901 |
| Regulation of leptin receptor expression in human papillary thyroid cancer cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120901 |
| Efficacy of hypomethylating agents in therapy-related myelodysplastic syndromes. | Leukemia research 20120901 |
| Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells. | Oncology reports 20120901 |
| Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation. | International journal of oncology 20120901 |
| Targeting the MAGE A3 antigen in pancreatic cancer. | Surgery 20120901 |
| Genomic methylation profiling combined with gene expression microarray reveals the aberrant methylation mechanism involved in nasopharyngeal carcinoma taxol resistance. | Anti-cancer drugs 20120901 |
| Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms. | Blood cancer journal 20120901 |
| Aberration of p73 promoter methylation in de novo myelodysplastic syndrome. | Hematology (Amsterdam, Netherlands) 20120901 |
| 5'-Aza-dC sensitizes paraquat toxic effects on PC12 cell. | Neuroscience letters 20120822 |
| Improving the outlook for myelodysplastic syndrome. | Journal of the National Cancer Institute 20120822 |
| CIITA is silenced by epigenetic mechanisms that prevent the recruitment of transactivating factors in rhabdomyosarcoma cells. | International journal of cancer 20120815 |
| MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma. | International journal of cancer 20120815 |
| Hypermethylation-mediated silencing of p14(ARF) in fibroblasts from idiopathic pulmonary fibrosis. | American journal of physiology. Lung cellular and molecular physiology 20120815 |
| Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators. | Toxicology and applied pharmacology 20120815 |
| Case report of isochromosome 17q in acute myeloid leukemia with myelodysplasia-related changes after treatment with a hypomethylating agent. | Genetics and molecular research : GMR 20120806 |
| Synergetic effects of DNA demethylation and histone deacetylase inhibition in primary rat hepatocytes. | Investigational new drugs 20120801 |
| Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas. | International journal of cancer 20120801 |
| Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype. | Leukemia & lymphoma 20120801 |
| Clone-derived human AF-amniotic fluid stem cells are capable of skeletal myogenic differentiation in vitro and in vivo. | Journal of tissue engineering and regenerative medicine 20120801 |
| Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death. | Genes, chromosomes & cancer 20120801 |
| Cell cycle regulation of human endometrial stromal cells during decidualization. | Reproductive sciences (Thousand Oaks, Calif.) 20120801 |
| A patient with acute megakaryoblastic leukaemia who achieved CRi after decitabine treatment. | Leukemia research 20120801 |
| Transcriptional silencing of the inhibin-α gene in human gastric carcinoma cells. | International journal of oncology 20120801 |
| Epigenetic alteration of CCDC67 and its tumor suppressor function in gastric cancer. | Carcinogenesis 20120801 |
| Rewiring drug-activated p53-regulatory network from suppressing to promoting tumorigenesis. | Journal of molecular cell biology 20120801 |
| 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status. | Oncology reports 20120801 |
| The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer. | Epigenetics 20120801 |
| DNA hypermethylation biomarkers to predict response to cisplatin treatment, radiotherapy or chemoradiation: the present state of art. | Cellular oncology (Dordrecht) 20120801 |
| Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. | The Journal of biological chemistry 20120720 |
| Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120720 |
| Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy. | International journal of radiation oncology, biology, physics 20120715 |
| Factors influencing epigenetic mechanisms and related diseases. | Antioxidants & redox signaling 20120715 |
| Promoter demethylation of Keap1 gene in human diabetic cataractous lenses. | Biochemical and biophysical research communications 20120706 |
| Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo. | International journal of cancer 20120701 |
| Durable complete remission after single agent decitabine in AML relapsing in extramedullary sites after allo-SCT. | Bone marrow transplantation 20120701 |
| Rap1GAP regulates renal cell carcinoma invasion. | Cancer letters 20120701 |
| 5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis. | Molecular & cellular proteomics : MCP 20120701 |
| Treatment with the cancer drugs decitabine and doxorubicin induces human skin keratinocytes to express Oct4 and the OCT4 regulator mir-145. | The Journal of dermatology 20120701 |
| cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120701 |
| Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers. | Laboratory investigation; a journal of technical methods and pathology 20120701 |
| Assessing signaling pathways associated with in vitro resistance to cytotoxic agents in AML. | Leukemia research 20120701 |
| Epigenetics and vitrification of embryos: one step forward and many raised equivocal questions. | Fertility and sterility 20120701 |
| Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor suppressor in hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120701 |
| Epigenetic inactivation of PLCD1 in chronic myeloid leukemia. | International journal of molecular medicine 20120701 |
| Overexpression of IFITM1 has clinicopathologic effects on gastric cancer and is regulated by an epigenetic mechanism. | The American journal of pathology 20120701 |
| Effect of 5-aza-2'-deoxycytidine on methylation of the putative imprinted control region of H19 during the in vitro development of vitrified bovine two-cell embryos. | Fertility and sterility 20120701 |
| Epigenetic regulation of cancer stem cell genes in triple-negative breast cancer. | The American journal of pathology 20120701 |
| 5-aza-2'-deoxycytidine improves the sensitivity of endometrial cancer cells to progesterone therapy. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20120701 |
| Myelodysplastic syndromes: 2012 update on diagnosis, risk-stratification, and management. | American journal of hematology 20120701 |
| Myelodysplastic syndromes: therapy and outlook. | The American journal of medicine 20120701 |
| Immunization with WT1-derived peptides by tattooing inhibits the growth of TRAMP-C2 prostate tumor in mice. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20120701 |
| Prostaglandin E2 induces growth inhibition, apoptosis and differentiation in T and B cell-derived acute lymphoblastic leukemia cell lines (CCRF-CEM and Nalm-6). | Prostaglandins, leukotrienes, and essential fatty acids 20120701 |
| Expression and functions of μ-opioid receptors and cannabinoid receptors type 1 in T lymphocytes. | Annals of the New York Academy of Sciences 20120701 |
| SDF-1/CXCR4 signal is involved in decreased expression of p57kip2 in de novo MDS patients. | Hematology (Amsterdam, Netherlands) 20120701 |
| [Effective treatment of myelodysplastic syndromes-refractory anemia with excess blasts type II by decitabine: a case report]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120701 |
| Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia. | Blood 20120621 |
| Development and validation of a liquid chromatography-tandem mass spectrometry method for quantification of decitabine in rat plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120615 |
| The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. | Nature 20120614 |
| XAF1 is frequently methylated in human esophageal cancer. | World journal of gastroenterology 20120614 |
| Abundant expression and hemimethylation of C19MC in cell cultures from placenta-derived stromal cells. | Biochemical and biophysical research communications 20120608 |
| Correlation between T-cadherin gene expression and aberrant methylation of T-cadherin promoter in human colon carcinoma cells. | Medical oncology (Northwood, London, England) 20120601 |
| Reactivation of Syk gene by AZA suppresses metastasis but not proliferation of breast cancer cells. | Medical oncology (Northwood, London, England) 20120601 |
| Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer. | International journal of cancer 20120601 |
| Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells. | The Journal of nutritional biochemistry 20120601 |
| Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers. | International journal of cancer 20120601 |
| Epigenetic silencing of the tumor suppressor klotho in human breast cancer. | Breast cancer research and treatment 20120601 |
| Curcumin causes promoter hypomethylation and increased expression of FANCF gene in SiHa cell line. | Molecular and cellular biochemistry 20120601 |
| Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study. | Cancer chemotherapy and pharmacology 20120601 |
| TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma. | EMBO molecular medicine 20120601 |
| microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis. | Oncology reports 20120601 |
| Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of cloned cattle. | Cellular reprogramming 20120601 |
| Global methylation analysis identifies PITX2 as an upstream regulator of the androgen receptor and IGF-I receptor genes in prostate cancer. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120601 |
| Molecular features of hepatosplenic T-cell lymphoma unravels potential novel therapeutic targets. | Blood 20120601 |
| DNA demethylating agent decitabine increases AQP5 expression and restores salivary function. | Journal of dental research 20120601 |
| Chronic myelomonocytic leukemia: 2012 update on diagnosis, risk stratification, and management. | American journal of hematology 20120601 |
| Pharmacological unmasking microarray approach-based discovery of novel DNA methylation markers for hepatocellular carcinoma. | Journal of Korean medical science 20120601 |
| RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas. | Neoplasia (New York, N.Y.) 20120601 |
| [Effect of proliferation inhibition and PTEN gene expression induced by decitabine combined with daunorubicin on HL-60 cell line]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120601 |
| Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo. | Oncogene 20120531 |
| The mitogen-activated protein kinase phosphatase-1 (MKP-1) gene is a potential methylation biomarker for malignancy of breast cancer. | Experimental & molecular medicine 20120531 |
| Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia. | Blood 20120531 |
| RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia. | Blood 20120531 |
| Anti-tumor effect of 5-aza-2'-deoxycytidine by inhibiting telomerase activity in hepatocellular carcinoma cells. | World journal of gastroenterology 20120521 |
| Azacitidine-associated Sweet's syndrome. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120515 |
| Aberrant methylation of SPARC in human hepatocellular carcinoma and its clinical implication. | World journal of gastroenterology 20120507 |
| Epigenetic regulation of 5-lipoxygenase in the phenotypic plasticity of valvular interstitial cells associated with aortic valve stenosis. | FEBS letters 20120507 |
| 5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand. | Blood 20120503 |
| Notch pathway activation induces neuroblastoma tumor cell growth arrest. | Pediatric blood & cancer 20120501 |
| Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma. | Cell biology international 20120501 |
| Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501 |
| DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia. | Leukemia 20120501 |
| Proteomic analysis identifies differentially expressed proteins in AML1/ETO acute myeloid leukemia cells treated with DNMT inhibitors azacitidine and decitabine. | Leukemia research 20120501 |
| Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling. | International journal of oncology 20120501 |
| Tumor suppressor gene BLU is frequently downregulated by promoter hypermethylation in myelodysplastic syndrome. | Journal of cancer research and clinical oncology 20120501 |
| DNA methylation status of REIC/Dkk-3 gene in human malignancies. | Journal of cancer research and clinical oncology 20120501 |
| Commentary on paper: 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene (Chachadi et al.). | The international journal of biochemistry & cell biology 20120501 |
| Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo. | Journal of immunology (Baltimore, Md. : 1950) 20120501 |
| Epigenetic resensitization to platinum in ovarian cancer. | Cancer research 20120501 |
| [Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and methylation of CHFR in human laryngreal carcinoma cell line]. | Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20120501 |
| [The role of hypermethylation in promoter region of ubiquitin carboxyl-terminal hydrolase L1 in human esophageal cancer]. | Zhonghua nei ke za zhi 20120501 |
| The differentiating and apoptotic effects of 2-aza-5'-deoxycytidine are dependent on the PU.1 expression level in PU.1-transgenic K562 cells. | Biochemical and biophysical research communications 20120420 |
| [A case report of undifferentiated connective tissue disease associated myelodysplastic]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20120418 |
| Identification of methylation-dependent regulatory elements for intergenic miRNAs in human H4 cells. | Biochemical and biophysical research communications 20120406 |
| Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth. | International journal of cancer 20120401 |
| Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20120401 |
| MicroRNA regulation via DNA methylation during the morula to blastocyst transition in mice. | Molecular human reproduction 20120401 |
| AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401 |
| Hypermethylation of Sox17 gene is useful as a molecular diagnostic application in early gastric cancer. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401 |
| DNA methylation contributes to the regulation of sclerostin expression in human osteocytes. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20120401 |
| Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation. | Kidney international 20120401 |
| Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells. | Oncology reports 20120401 |
| SFRP1 promoter methylation and expression in human trabecular meshwork cells. | Experimental eye research 20120401 |
| Discovery of drugs that possess activity against feline leukemia virus. | The Journal of general virology 20120401 |
| Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1. | Antimicrobial agents and chemotherapy 20120401 |
| DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs. | Biochemical pharmacology 20120401 |
| Promoter methylation of aminopeptidase N/CD13 in malignant melanoma. | Carcinogenesis 20120401 |
| Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia. | American journal of hematology 20120401 |
| A simple method for high-throughput quantification of genome-wide DNA methylation by fluorescence polarization. | Epigenetics 20120401 |
| Promoter methylation regulates cigarette smoke-stimulated cyclooxygenase-2 expression in esophageal squamous cell carcinoma. | Journal of digestive diseases 20120401 |
| Reactivation of Silenced WT1 Transgene by Hypomethylating Agents - Implications for in vitro Modeling of Chemoimmunotherapy. | Immune network 20120401 |
| Hypomethylation mediated by decreased DNMTs involves in the activation of proto-oncogene MPL in TK6 cells treated with hydroquinone. | Toxicology letters 20120325 |
| Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells. | Cancer cell 20120320 |
| Identification of the A kinase anchor protein 12 (AKAP12) gene as a candidate tumor suppressor of hepatocellular carcinoma. | Journal of surgical oncology 20120315 |
| Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120315 |
| Interstitial lung disease associated with azacitidine use: a case report. | American journal of therapeutics 20120301 |
| Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence. | Head & neck 20120301 |
| The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells. | International journal of cancer 20120301 |
| Feasibility of hypomethylating agents followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome. | Bone marrow transplantation 20120301 |
| Aberrant methylation of RASSF2A in human pancreatic ductal adenocarcinoma and its relation to clinicopathologic features. | Pancreas 20120301 |
| Comparative effects of retinoic acid, vitamin D and resveratrol alone and in combination with adenosine analogues on methylation and expression of phosphatase and tensin homologue tumour suppressor gene in breast cancer cells. | The British journal of nutrition 20120301 |
| How to manage lower-risk myelodysplastic syndromes. | Leukemia 20120301 |
| Down-regulation of CXCL12 by DNA hypermethylation and its involvement in gastric cancer metastatic progression. | Digestive diseases and sciences 20120301 |
| A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy. | Haematologica 20120301 |
| DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells. | Cancer letters 20120301 |
| Promoter methylation of the bone morphogenetic protein 6 gene in multiple myeloma. | Oncology reports 20120301 |
| Downregulation of MUC1 expression and its recognition by CD8⁺ T cells on the surface of malignant pleural mesothelioma cells treated with HDACi. | European journal of immunology 20120301 |
| Optimizing hypomethylating agents in myelodysplastic syndromes. | Current opinion in hematology 20120301 |
| 5-Aza-2'-deoxycytidine increases the sensitivity of human bone marrow mesenchymal stem cells to chemotherapeutic agents by demethylation of p73. | Journal of pediatric hematology/oncology 20120301 |
| Decitabine for acute myeloid leukemia. | Expert review of anticancer therapy 20120301 |
| Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1. | Anticancer research 20120301 |
| Increased DNA methyltransferase activity and DNA methylation following Epidermal Growth Factor stimulation in ovarian cancer cells. | Epigenetics 20120301 |
| [Effect of methylation inhibitor on EphB4 gene expression, proliferation and apoptosis in CEM cells]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20120301 |
| [Therapeutic effect of in vitro 5-aza-2'-deoxycytidine combined with imatinib on gastrointestinal stromal tumor]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20120301 |
| Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions. | PLoS genetics 20120301 |
| Expression profiling after induction of demethylation in MCF-7 breast cancer cells identifies involvement of TNF-α mediated cancer pathways. | Molecules and cells 20120227 |
| Position effect variegation and epigenetic modification of a transgene in a pig model. | Genetics and molecular research : GMR 20120216 |
| Aberrant DNA methylation and tumor suppressive activity of the EBF3 gene in gastric carcinoma. | International journal of cancer 20120215 |
| Epigenetic inactivation of secreted frizzled-related protein 2 in esophageal squamous cell carcinoma. | World journal of gastroenterology 20120214 |
| Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine. | Blood 20120202 |
| ENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumours. | Journal of cellular and molecular medicine 20120201 |
| Deoxycytidine kinase is overexpressed in poor outcome breast cancer and determines responsiveness to nucleoside analogs. | Breast cancer research and treatment 20120201 |
| CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors. | Leukemia 20120201 |
| Histone H4 deacetylation down-regulates catalase gene expression in doxorubicin-resistant AML subline. | Cell biology and toxicology 20120201 |
| Heparanase expression is associated with histone modifications in glioblastoma. | International journal of oncology 20120201 |
| Analysis of aberrant methylation in DNA repair genes during malignant transformation of human bronchial epithelial cells induced by cadmium. | Toxicological sciences : an official journal of the Society of Toxicology 20120201 |
| Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis. | World journal of surgery 20120201 |
| Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence. | Cancer prevention research (Philadelphia, Pa.) 20120201 |
| Light-regulated and cell-specific methylation of the maize PEPC promoter. | Journal of experimental botany 20120201 |
| CRABP-II methylation: a critical determinant of retinoic acid resistance of medulloblastoma cells. | Molecular oncology 20120201 |
| PCDH17 gene promoter demethylation and cell cycle arrest by genistein in gastric cancer. | Histology and histopathology 20120201 |
| Oligonucleotide-mediated gene editing is underestimated in cells expressing mutated green fluorescent protein and is positively associated with target protein expression. | The journal of gene medicine 20120201 |
| Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma. | Molecular cancer research : MCR 20120201 |
| Influence of epigenetic modifications of the interleukin-10 promoter on IL10 gene expression. | European journal of oral sciences 20120201 |
| p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies. | Seminars in oncology 20120201 |
| Epigenetic modulation to enable antigen-specific T-cell therapy of colorectal cancer. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20120201 |
| [Decitabine for treatment of myelodysplastic syndrome in an elderly patient and review of literature]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120201 |
| [Decitabine inhibits cell proliferation and induces apoptosis of all-trans retinoid acid-resistant acute promyelocytic leukemia NB4-R2 cell line]. | Zhongguo shi yan xue ye xue za zhi 20120201 |
| Rapid turnover of DNA methylation in human cells. | Epigenetics 20120201 |
| Promoter methylation status of VEGF receptor genes: a possible epigenetic biomarker to anticipate the efficacy of intracellular-acting VEGF-targeted drugs in cancer cells. | Epigenetics 20120201 |
| [The comparison of short-term efficacies between decitabine and HA regimen for MDS/AML patients]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120201 |
| DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines. | International journal of cancer 20120115 |
| DNA methylation of the 5'-untranslated region at +298 and +351 represses BACE1 expression in mouse BV-2 microglial cells. | Biochemical and biophysical research communications 20120106 |
| Enhancement of chemotherapeutic efficacy in hypermethylator breast cancer cells through targeted and pharmacologic inhibition of DNMT3b. | Breast cancer research and treatment 20120101 |
| DNA hypermethylation and histone modifications downregulate the candidate tumor suppressor gene RRP22 on 22q12 in human gliomas. | Brain pathology (Zurich, Switzerland) 20120101 |
| Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy. | Advances in hematology 20120101 |
| Identification of a potent epigenetic biomarker for resistance to camptothecin and poor outcome to irinotecan-based chemotherapy in colon cancer. | International journal of oncology 20120101 |
| HSPB8 is methylated in hematopoietic malignancies and overexpression of HSPB8 exhibits antileukemia effect. | Experimental hematology 20120101 |
| Epigenetic drug discovery: targeting DNA methyltransferases. | Journal of biomolecular screening 20120101 |
| A cost-effectiveness analysis of using azacitidine vs. decitabine in treating patients with myelodysplastic syndromes. | Journal of medical economics 20120101 |
| 5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120101 |
| Effect of 5-Aza-2'-deoxycytidine on SLC22A18 in glioma U251 cells. | Molecular medicine reports 20120101 |
| Molecular determinants of retinoic acid sensitivity in pancreatic cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120101 |
| CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells. | Experimental dermatology 20120101 |
| Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life. | Endocrinology 20120101 |
| Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas. | Oral oncology 20120101 |
| Antiretroviral activity of 5-azacytidine during treatment of a HTLV-1 positive myelodysplastic syndrome with autoimmune manifestations. | Virology journal 20120101 |
| Combination strategies in myelodysplastic syndromes. | International journal of hematology 20120101 |
| Ovarian cancer: opportunity for targeted therapy. | Journal of oncology 20120101 |
| Why do results conflict regarding the prognostic value of the methylation status in colon cancers? The role of the preservation method. | BMC cancer 20120101 |
| TGFBI promoter hypermethylation correlating with paclitaxel chemoresistance in ovarian cancer. | Journal of experimental & clinical cancer research : CR 20120101 |
| DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4). | BMC cancer 20120101 |
| Defining the sister rat mammary tumor cell lines HH-16 cl.2/1 and HH-16.cl.4 as an in vitro cell model for Erbb2. | PloS one 20120101 |
| Regulation of opioid and cannabinoid receptor genes in human neuroblastoma and T cells by the epigenetic modifiers trichostatin A and 5-aza-2'-deoxycytidine. | Neuroimmunomodulation 20120101 |
| Sensitive quantitative analysis of murine LINE1 DNA methylation using high resolution melt analysis. | Epigenetics 20120101 |
| [Demethylating medication in myelodysplastic syndrome]. | Nederlands tijdschrift voor geneeskunde 20120101 |
| Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells. | Epigenetics & chromatin 20120101 |
| Drug transporter regulation in tumors by DNA methylation. | Genome medicine 20120101 |
| Molecular basis of triple negative breast cancer and implications for therapy. | International journal of breast cancer 20120101 |
| Oncolytic virotherapy for hematological malignancies. | Advances in virology 20120101 |
| Methylation of the KEAP1 gene promoter region in human colorectal cancer. | BMC cancer 20120101 |
| TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia. | PloS one 20120101 |
| DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo. | Chemotherapy 20120101 |
| Emerging pharmacotherapies for adult patients with acute lymphoblastic leukemia. | Clinical Medicine Insights. Oncology 20120101 |
| Autosomal monoallelic expression in the mouse. | Genome biology 20120101 |
| Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models. | Cancer cell international 20120101 |
| Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine. | Nucleosides, nucleotides & nucleic acids 20120101 |
| Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation. | Clinical laboratory 20120101 |
| Different involvement of DNA methylation and histone deacetylation in the expression of solute-carrier transporters in 4 colon cancer cell lines. | Biological & pharmaceutical bulletin 20120101 |
| NYESO-1/LAGE-1s and PRAME are targets for antigen specific T cells in chondrosarcoma following treatment with 5-Aza-2-deoxycitabine. | PloS one 20120101 |
| Screening for epigenetically masked genes in colorectal cancer Using 5-Aza-2'-deoxycytidine, microarray and gene expression profile. | Cancer genomics & proteomics 20120101 |
| IGFBP3 impedes aggressive growth of pediatric liver cancer and is epigenetically silenced in vascular invasive and metastatic tumors. | Molecular cancer 20120101 |
| Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer. | PloS one 20120101 |
| Epigenetic disregulation in oral cancer. | International journal of molecular sciences 20120101 |
| The silencing of RECK gene is associated with promoter hypermethylation and poor survival in hepatocellular carcinoma. | International journal of biological sciences 20120101 |
| In planta assays involving epigenetically silenced genes reveal inhibition of cytosine methylation by genistein. | Plant methods 20120101 |
| DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells. | PloS one 20120101 |
| DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity. | Radiation oncology (London, England) 20120101 |
| Epigenetic modification of TLRs in leukocytes is associated with increased susceptibility to Salmonella enteritidis in chickens. | PloS one 20120101 |
| Milk fermented by Propionibacterium freudenreichii induces apoptosis of HGT-1 human gastric cancer cells. | PloS one 20120101 |
| Folic acid supplementation increases survival and modulates high risk HPV-induced phenotypes in oral squamous cell carcinoma cells and correlates with p53 mRNA transcriptional down-regulation. | Cancer cell international 20120101 |
| Reversin increase the plasticity of bone marrow-derived mesenchymal stem cell for generation of cardiomyocyte in vitro. | Acta medica Indonesiana 20120101 |
| Low-dose Cd induces hepatic gene hypermethylation, along with the persistent reduction of cell death and increase of cell proliferation in rats and mice. | PloS one 20120101 |
| Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1 in tumors of epithelial, NK- and B-cell origins. | BMC cancer 20120101 |
| Depletion of OLFM4 gene inhibits cell growth and increases sensitization to hydrogen peroxide and tumor necrosis factor-alpha induced-apoptosis in gastric cancer cells. | Journal of biomedical science 20120101 |
| Androgen receptor expression predicts breast cancer survival: the role of genetic and epigenetic events. | BMC cancer 20120101 |
| Multi-target siRNA based on DNMT3A/B homologous conserved region influences cell cycle and apoptosis of human prostate cancer cell line TSU-PR1. | Genetics and molecular biology 20120101 |
| HIV RNA suppression and immune restoration: can we do better? | Clinical & developmental immunology 20120101 |
| [5-aza-2'-deoxycytidine-induced inhibition of CDH13 expression and its inhibitory effect on methylation status in human colon cancer cells in vitro and on growth of xenograft in nude mice]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20120101 |
| Novel therapies for aggressive B-cell lymphoma. | Advances in hematology 20120101 |
| Cell cycle gene networks are associated with melanoma prognosis. | PloS one 20120101 |
| A Case of Atypical Delayed and Prolonged Hematologic Toxicity With Azacitidine in Chronic Myelomonocytic Leukemia (CMML) and Review of Literature. | Mediterranean journal of hematology and infectious diseases 20120101 |
| Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation. | PloS one 20120101 |
| Utility of DNA methyltransferase inhibitors for the treatment of myelodysplastic syndromes. | Current pharmaceutical design 20120101 |
| Approach to new therapeutics: investigation by the use of MDS-derived cell lines. | Current pharmaceutical design 20120101 |
| Vorinostat approved in Japan for treatment of cutaneous T-cell lymphomas: status and prospects. | OncoTargets and therapy 20120101 |
| RASSF Signalling and DNA Damage: Monitoring the Integrity of the Genome? | Molecular biology international 20120101 |
| Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation. | PloS one 20120101 |
| Surf the post-translational modification network of p53 regulation. | International journal of biological sciences 20120101 |
| Arabidopsis RPT2a, 19S proteasome subunit, regulates gene silencing via DNA methylation. | PloS one 20120101 |
| TCUP: A Novel hAT Transposon Active in Maize Tissue Culture. | Frontiers in plant science 20120101 |
| Epigenetic dysregulation in laryngeal squamous cell carcinoma. | Journal of oncology 20120101 |
| Epigenetics modifications and therapeutic prospects in human thyroid cancer. | Frontiers in endocrinology 20120101 |
| Acute myeloid leukemia: focus on novel therapeutic strategies. | Clinical Medicine Insights. Oncology 20120101 |
| FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors. | Anemia 20120101 |
| Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. | PloS one 20120101 |
| Demethylation of the coding region triggers the activation of the human testis-specific PDHA2 gene in somatic tissues. | PloS one 20120101 |
| Effect of AGM and fetal liver-derived stromal cell lines on globin expression in adult baboon (P. anubis) bone marrow-derived erythroid progenitors. | PloS one 20120101 |
| Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells. | Journal of biomedicine & biotechnology 20120101 |
| Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation. | PloS one 20120101 |
| Effect of phenylhexyl isothiocyanate on aberrant histone H3 methylation in primary human acute leukemia. | Journal of hematology & oncology 20120101 |
| The effects of promoter methylation on downregulation of DAZAP2 in multiple myeloma cell lines. | PloS one 20120101 |
| Promoter DNA methylation regulates murine SUR1 (Abcc8) and SUR2 (Abcc9) expression in HL-1 cardiomyocytes. | PloS one 20120101 |
| Aberrant promoter methylation and expression of UTF1 during cervical carcinogenesis. | PloS one 20120101 |
| Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1. | Genes & cancer 20120101 |
| Gene expression profiling of the synergy of 5-aza-2'-deoxycytidine and paclitaxel against renal cell carcinoma. | World journal of surgical oncology 20120101 |
| Transcriptional regulation of hTREX84 in human cancer cells. | PloS one 20120101 |
| Expression of MUC17 is regulated by HIF1α-mediated hypoxic responses and requires a methylation-free hypoxia responsible element in pancreatic cancer. | PloS one 20120101 |
| Unlike pancreatic cancer cells pancreatic cancer associated fibroblasts display minimal gene induction after 5-aza-2'-deoxycytidine. | PloS one 20120101 |
| Mining gene expression signature for the detection of pre-malignant melanocytes and early melanomas with risk for metastasis. | PloS one 20120101 |
| Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers. | PloS one 20120101 |
| 5-aza-2'-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes. | PloS one 20120101 |
| Alterations of the WNT7A gene in clear cell renal cell carcinomas. | PloS one 20120101 |
| Decitabine induced transient cardiomyopathy: a case report. | Clinical Medicine Insights. Oncology 20120101 |
| Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas. | PloS one 20120101 |
| Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation. | PloS one 20120101 |
| MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in rats. | Toxicology 20111218 |
| Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression. | Cancer research 20111215 |
| 5-aza-2'-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel by decreasing LEF1/phospho-β-catenin expression. | Cancer letters 20111208 |
| Epigenetic inactivation of the hsa-miR-203 in haematological malignancies. | Journal of cellular and molecular medicine 20111201 |
| Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer. | Journal of hepatology 20111201 |
| The association between non-Hodgkin lymphoma and methylation of p73. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20111201 |
| Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine. | Cell biochemistry and function 20111201 |
| Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells. | Carcinogenesis 20111201 |
| Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer. | International journal of cancer 20111201 |
| The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression. | Genes, chromosomes & cancer 20111201 |
| Epigenetic regulation of glucose transporter 4 by estrogen receptor β. | Molecular endocrinology (Baltimore, Md.) 20111201 |
| Novel therapeutic approaches for acute lymphoblastic leukemia. | Hematology/oncology clinics of North America 20111201 |
| Mucins in human neoplasms: clinical pathology, gene expression and diagnostic application. | Pathology international 20111201 |
| What is the optimal induction strategy for older patients? | Best practice & research. Clinical haematology 20111201 |
| Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines. | Epigenetics 20111201 |
| Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer. | Oncotarget 20111201 |
| Epigenetic inactivation of the MIR34B/C in multiple myeloma. | Blood 20111124 |
| HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL. | Blood 20111117 |
| Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines. | International journal of cancer 20111115 |
| CpG methylation at the USF-binding site mediates cell-specific transcription of human ascorbate transporter SVCT2 exon 1a. | The Biochemical journal 20111115 |
| DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter. | Human molecular genetics 20111115 |
| Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111115 |
| MAGE: the spell is broken. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111115 |
| Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter. | FEBS letters 20111104 |
| Amyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line. | Biochemical and biophysical research communications 20111104 |
| CpG methylation prevents YY1-mediated transcriptional activation of the vimentin promoter. | Biochemical and biophysical research communications 20111104 |
| The neuronal pentraxin II gene (NPTX2) inhibit proliferation and invasion of pancreatic cancer cells in vitro. | Molecular biology reports 20111101 |
| Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells. | Breast cancer research and treatment 20111101 |
| 5-Aza-2'-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression. | International journal of cancer 20111101 |
| Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer. | International journal of cancer 20111101 |
| Reactivation of transgene expression by alleviating CpG methylation of the Rous sarcoma virus promoter in transgenic quail cells. | Molecular biotechnology 20111101 |
| A 5-aza-2'-deoxycytidine/valproate combination induces cytotoxic T-cell response against mesothelioma. | The European respiratory journal 20111101 |
| Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. | Digestive diseases and sciences 20111101 |
| Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors. | British journal of pharmacology 20111101 |
| Promoter hypermethylation of the CFTR gene and clinical/pathological features associated with non-small cell lung cancer. | Respirology (Carlton, Vic.) 20111101 |
| p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia. | Leukemia 20111101 |
| Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer. | Breast cancer research and treatment 20111101 |
| Epigenetic silencing of microRNA-373 plays an important role in regulating cell proliferation in colon cancer. | Oncology reports 20111101 |
| γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines. | International journal of radiation biology 20111101 |
| Differential down-modulation of HLA class I and II molecule expression on human tumor cell lines upon in vivo transfer. | Cancer immunology, immunotherapy : CII 20111101 |
| WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix. | Carcinogenesis 20111101 |
| Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer. | Cancer research 20111101 |
| Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia. | American journal of hematology 20111101 |
| Antiangiogenesis in myelodysplastic syndrome. | Current cancer drug targets 20111101 |
| Decitabine, independent of apoptosis, exerts its cytotoxic effects on cell growth in melanoma cells. | Environmental toxicology and pharmacology 20111101 |
| DNA methylation patterns of Brachypodium distachyon chromosomes and their alteration by 5-azacytidine treatment. | Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20111101 |
| 5-AZA-2'-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer. | Epigenetics 20111101 |
| The effect of epigenetic factors on differentiation of pancreatic progenitor cells into insulin-producing cells. | Transplantation proceedings 20111101 |
| [The clinical research of treatment by decitabine moderate or high-risk myelodysplastic syndrome patients]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20111101 |
| Aberrant DNA methylation and prostate cancer. | Current genomics 20111101 |
| p53-independent epigenetic repression of the p21(WAF1) gene in T-cell acute lymphoblastic leukemia. | The Journal of biological chemistry 20111028 |
| 5-aza-2'-deoxycytidine activates iron uptake and heme biosynthesis by increasing c-Myc nuclear localization and binding to the E-boxes of transferrin receptor 1 (TfR1) and ferrochelatase (Fech) genes. | The Journal of biological chemistry 20111028 |
| Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells. | Clinical epigenetics 20111026 |
| FMR1 CGG repeat lengths mediate different regulation of reporter gene expression in comparative transient and locus specific integration assays. | Gene 20111015 |
| A new look at immune privilege of the eye: dual role for the vision-related molecule retinoic acid. | Journal of immunology (Baltimore, Md. : 1950) 20111015 |
| Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinoma. | World journal of gastroenterology 20111007 |
| Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial. | Blood 20111006 |
| The expression of ADAM23 and its correlation with promoter methylation in non-small-cell lung carcinoma. | International journal of experimental pathology 20111001 |
| Aberrant CpG island hypermethylation and down-regulation of Oct-6 mRNA expression in human hepatocellular carcinoma. | Digestive diseases and sciences 20111001 |
| Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy. | Cancer 20111001 |
| A phase 1 trial dose-escalation study of tipifarnib on a week-on, week-off schedule in relapsed, refractory or high-risk myeloid leukemia. | Leukemia 20111001 |
| A prospective multicenter observational study of decitabine treatment in Korean patients with myelodysplastic syndrome. | Haematologica 20111001 |
| CDH4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma. | Cancer letters 20111001 |
| Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineage. | Bone 20111001 |
| Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL. | Carcinogenesis 20111001 |
| Expression and regulation of B7-H3 immunoregulatory receptor, in human mesothelial and mesothelioma cells: immunotherapeutic implications. | Journal of cellular physiology 20111001 |
| Sex hormone control of left ventricular structure/function: mechanistic insights using echocardiography, expression, and DNA methylation analyses in adult mice. | American journal of physiology. Heart and circulatory physiology 20111001 |
| Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer. | Molecular oncology 20111001 |
| Human leptin tissue distribution, but not weight loss-dependent change in expression, is associated with methylation of its promoter. | Epigenetics 20111001 |
| Hematopoietic growth factors in myelodysplastic syndromes. | Seminars in oncology 20111001 |
| Treatment of higher-risk myelodysplastic syndrome. | Seminars in oncology 20111001 |
| Failure of hypomethylating agent-based therapy in myelodysplastic syndromes. | Seminars in oncology 20111001 |
| [Novel therapeutics for myelodysplastic syndromes]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20111001 |
| [Silence mechanism of WT1 gene in leukemic cell line U937]. | Zhongguo shi yan xue ye xue za zhi 20111001 |
| Epigenomics in hematopoietic transplantation: novel treatment strategies. | Epigenomics 20111001 |
| Methylation of adrenergic β1 receptor is a potential epigenetic mechanism controlling antihypertensive response to metoprolol. | Indian journal of biochemistry & biophysics 20111001 |
| Induction of regulatory T cells by green tea polyphenol EGCG. | Immunology letters 20110930 |
| DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. | Blood 20110929 |
| Successful allogeneic stem-cell transplantation in a patient with myelodysplastic syndrome with hemodialysis-dependent end-stage renal disease. | Transplantation 20110927 |
| Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. | Oncogene 20110922 |
| Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells. | Oncogene 20110915 |
| Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor. | Analytical chemistry 20110915 |
| A pilot study of subcutaneous decitabine in β-thalassemia intermedia. | Blood 20110908 |
| Dickkopf3 overexpression inhibits pancreatic cancer cell growth in vitro. | World journal of gastroenterology 20110907 |
| [Effects of 5-Aza-2'-deoxycytidine on the carcinogenesis of colorectal cancer in mouse and the in vivo expression of p16/CDKN(2) mRNA]. | Zhonghua yi xue za zhi 20110906 |
| Hypomethylating agents for the treatment of acute myeloid leukemia in the elderly: for all, none, or which patients? | Cancer 20110901 |
| Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2'-deoxycytidine. | Leukemia research 20110901 |
| Effect of trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells. | Molecular and cellular biochemistry 20110901 |
| Increased PRAME antigen-specific killing of malignant cell lines by low avidity CTL clones, following treatment with 5-Aza-2'-Deoxycytidine. | Cancer immunology, immunotherapy : CII 20110901 |
| Co-expression of laminin β3 and γ2 chains and epigenetic inactivation of laminin α3 chain in gastric cancer. | International journal of oncology 20110901 |
| MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells to facilitate cytotoxic T lymphocyte-mediated tumor cell killing. | Cancer immunology, immunotherapy : CII 20110901 |
| Decreased expression of protease-activated receptor 4 in human gastric cancer. | The international journal of biochemistry & cell biology 20110901 |
| The DNA methylome of benign and malignant parathyroid tumors. | Genes, chromosomes & cancer 20110901 |
| Transformation-dependent silencing of tumor-selective apoptosis-inducing TRAIL by DNA hypermethylation is antagonized by decitabine. | Molecular cancer therapeutics 20110901 |
| Epigenetic silencing of MIR203 in multiple myeloma. | British journal of haematology 20110901 |
| Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer. | Cancer biology & therapy 20110901 |
| Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1. | Cancer research 20110901 |
| Definition of the landscape of promoter DNA hypomethylation in liver cancer. | Cancer research 20110901 |
| Hypomethylating agents in the treatment of myelodysplastic syndromes and myeloid leukemia. | Current cancer drug targets 20110901 |
| NOR1 is an HSF1- and NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma. | Carcinogenesis 20110901 |
| Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a phase I study. | American journal of hematology 20110901 |
| TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers. | Epigenetics 20110901 |
| Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells. | Epigenetics 20110901 |
| Chromium(VI) causes down regulation of biotinidase in human bronchial epithelial cells by modifications of histone acetylation. | Toxicology letters 20110828 |
| Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML. | Blood 20110811 |
| Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni. | Nature communications 20110809 |
| Identification of methylation profile of HOX genes in extrahepatic cholangiocarcinoma. | World journal of gastroenterology 20110807 |
| Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20110801 |
| Interferon-alpha induces reversible DNA demethylation of the interferon-induced transmembrane protein-3 core promoter in human melanoma cells. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110801 |
| DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. | European journal of cancer (Oxford, England : 1990) 20110801 |
| Inhibition of p53-p21 pathway promotes the differentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes. | Molecular and cellular biochemistry 20110801 |
| The effects of 5-aza-2'- deoxycytidine and trichostatin A on gene expression and DNA methylation status in cloned bovine blastocysts. | Cellular reprogramming 20110801 |
| Klotho, an anti-senescence related gene, is frequently inactivated through promoter hypermethylation in colorectal cancer. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110801 |
| Delineation of the molecular mechanisms of nucleoside recognition by cytidine deaminase through virtual screening. | ChemMedChem 20110801 |
| Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma. | Melanoma research 20110801 |
| MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer. | Carcinogenesis 20110801 |
| Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110801 |
| The effect of decitabine on megakaryocyte maturation and platelet release. | Thrombosis and haemostasis 20110801 |
| The depletion of DNA methyltransferase-1 and the epigenetic effects of 5-aza-2'deoxycytidine (decitabine) are differentially regulated by cell cycle progression. | Epigenetics 20110801 |
| The application of delivery systems for DNA methyltransferase inhibitors. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20110801 |
| Hematologic outcomes of myelodysplastic syndromes treatment with hypomethylating agents in community practice. | Clinical lymphoma, myeloma & leukemia 20110801 |
| [Hypomethylating agents for the treatment of myelodysplastic syndromes]. | Bulletin du cancer 20110801 |
| [Effects of decitabine on biological behavior of U266 cells]. | Zhongguo shi yan xue ye xue za zhi 20110801 |
| Downregulation of ARFGEF1 and CAMK2B by promoter hypermethylation in breast cancer cells. | BMB reports 20110801 |
| Improving the outcomes of elderly patients with acute myeloid leukemia in a Brazilian University Hospital. | Clinics (Sao Paulo, Brazil) 20110801 |
| Methylation-associated dysregulation of the suppressor of cytokine signaling-3 gene in multiple myeloma. | Epigenetics 20110801 |
| Construction of eukaryotic expression vector of TSLC1 gene. | Archives of medical science : AMS 20110801 |
| [Mechanism of loss of human esophageal cancer-related gene 4 (ECRG4) gene expression in esophageal squamous cell carcinoma cell line EC9706]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110801 |
| Role of DNA methylation in head and neck cancer. | Clinical epigenetics 20110801 |
| Epigenetic regulation of prostate cancer. | Clinical epigenetics 20110801 |
| Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies. | Clinical epigenetics 20110801 |
| Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applications. | Clinical epigenetics 20110801 |
| 5-Aza-2'-deoxycytidine stress response and apoptosis in prostate cancer. | Clinical epigenetics 20110801 |
| Treatment of poor-risk myelodysplastic syndromes and acute myeloid leukemia with a combination of 5-azacytidine and valproic acid. | Clinical epigenetics 20110801 |
| Epigenetic approaches in stem cell transplantation. | Clinical epigenetics 20110801 |
| The role of promoter methylation in Epstein-Barr virus (EBV) microRNA expression in EBV-infected B cell lines. | Experimental & molecular medicine 20110731 |
| Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells. | Toxicology 20110729 |
| Identification of epigenetically silenced genes in human pancreatic cancer by a novel method 'microarray coupled with methyl-CpG targeted transcriptional activation' (MeTA-array). | Biochemical and biophysical research communications 20110722 |
| Epigenetic mechanisms for silencing glutathione S-transferase m2 expression by hypermethylated specificity protein 1 binding in lung cancer. | Cancer 20110715 |
| MicroRNA-146a downregulates NFκB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110715 |
| Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia. | Cell cycle (Georgetown, Tex.) 20110715 |
| Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer. | British journal of cancer 20110712 |
| The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO. | Oncogene 20110707 |
| Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes. | Leukemia research 20110701 |
| IGFBP7 is a p53 target gene inactivated in human lung cancer by DNA hypermethylation. | Lung cancer (Amsterdam, Netherlands) 20110701 |
| Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells. | Journal of cellular biochemistry 20110701 |
| Recurrent DNMT3A mutations in patients with myelodysplastic syndromes. | Leukemia 20110701 |
| Changes in the levels of DNA methylation in testis and liver of SD rats neonatally exposed to 5-aza-2'-deoxycytidine and cadmium. | Journal of applied toxicology : JAT 20110701 |
| The in vivo induction of sister chromatid exchange by the demethylating agent 5-aza-2'-deoxycytidine. | Mutagenesis 20110701 |
| DNMT3B gene amplification predicts resistance to DNA demethylating drugs. | Genes, chromosomes & cancer 20110701 |
| Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. | Cancer science 20110701 |
| Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells. | Leukemia research 20110701 |
| Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
| EFEMP1 as a novel DNA methylation marker for prostate cancer: array-based DNA methylation and expression profiling. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
| Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110701 |
| Genome-wide analysis of promoter methylation associated with gene expression profile in pancreatic adenocarcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
| The Levels of H11/HspB8 DNA methylation in human melanoma tissues and xenografts are a critical molecular marker for 5-Aza-2'-deoxycytidine therapy. | Cancer investigation 20110701 |
| [High glucose induce the demethylation of CTGF promoter and gene expression]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110701 |
| [Epigenetic therapy in myelodysplastic syndromes]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20110701 |
| [Treatment of two chronic myelomonocytic leukemia patients with Decitabine]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110701 |
| Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway. | Molecules and cells 20110630 |
| Azacytidine impairs NK cell reactivity while decitabine augments NK cell responsiveness toward stimulation. | International journal of cancer 20110615 |
| Activity of azacitidine in chronic myelomonocytic leukemia. | Cancer 20110615 |
| Thrombomodulin is silenced in malignant mesothelioma by a poly(ADP-ribose) polymerase-1-mediated epigenetic mechanism. | The Journal of biological chemistry 20110603 |
| Phosphorylation of human DNMT1: implication of cyclin-dependent kinases. | Biochemical and biophysical research communications 20110603 |
| Promoter hypomethylation up-regulates CD147 expression through increasing Sp1 binding and associates with poor prognosis in human hepatocellular carcinoma. | Journal of cellular and molecular medicine 20110601 |
| The detection of CMV pp65 and IE1 in glioblastoma multiforme. | Journal of neuro-oncology 20110601 |
| Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring. | Annals of hematology 20110601 |
| Senescence-associated gene YPEL3 is downregulated in human colon tumors. | Annals of surgical oncology 20110601 |
| Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20110601 |
| Expression of the human cancer/testis antigen NY-SAR-35 is activated by CpG island hypomethylation. | Biotechnology letters 20110601 |
| Hepatitis B virus X protein overcomes all-trans retinoic acid-induced cellular senescence by downregulating levels of p16 and p21 via DNA methylation. | The Journal of general virology 20110601 |
| Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells. | Endocrine-related cancer 20110601 |
| Epigenetic regulation of proMMP-1 expression in the HT1080 human fibrosarcoma cell line. | International journal of oncology 20110601 |
| Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. | Biochemical pharmacology 20110601 |
| Clinical significance of expression of Hint1 and potential epigenetic mechanism in gastric cancer. | International journal of oncology 20110601 |
| Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant glioma cells. | Molecular oncology 20110601 |
| A demethylating agent enhances chemosensitivity to vinblastine in a xenograft model of renal cell carcinoma. | International journal of oncology 20110601 |
| Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell lines. | Oncology reports 20110601 |
| Improved response to nab-paclitaxel compared with cremophor-solubilized paclitaxel is independent of secreted protein acidic and rich in cysteine expression in non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110601 |
| Ultra-performance liquid chromatography/tandem mass spectrometry for accurate quantification of global DNA methylation in human sperms. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110601 |
| Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia. | The Journal of clinical investigation 20110601 |
| Use of hypomethylating agents and associated care in patients with myelodysplastic syndromes: a claims database study. | Current medical research and opinion 20110601 |
| Epigenetic regulation of microRNA-10b and targeting of oncogenic MAPRE1 in gastric cancer. | Epigenetics 20110601 |
| 2´-deoxy-5,6-dihydro-5-azacytidine - a less toxic alternative of 2´-deoxy-5-azacytidine: a comparative study of hypomethylating potential. | Epigenetics 20110601 |
| Myelodysplastic syndromes: 2011 update on diagnosis, risk-stratification, and management. | American journal of hematology 20110601 |
| HDAC1 inhibition by maspin abrogates epigenetic silencing of glutathione S-transferase pi in prostate carcinoma cells. | Molecular cancer research : MCR 20110601 |
| Global gene disruption in human cells to assign genes to phenotypes by deep sequencing. | Nature biotechnology 20110601 |
| MicroRNAs in Human Diseases: From Cancer to Cardiovascular Disease. | Immune network 20110601 |
| Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients. | British journal of cancer 20110524 |
| Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer. | British journal of cancer 20110524 |
| Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110520 |
| Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions. | International journal of cancer 20110515 |
| Acute myocarditis induced by hypomethylating agents. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110510 |
| Epigenetic modulation enhances the therapeutic effect of anti-IL-13R(alpha)2 antibody in human mesothelioma xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110501 |
| Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer. | International journal of molecular medicine 20110501 |
| Regulation of cancer cell proliferation by caveolin-2 down-regulation and re-expression. | International journal of oncology 20110501 |
| Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer. | Thyroid : official journal of the American Thyroid Association 20110501 |
| Pharmacokinetic evaluation of decitabine for the treatment of leukemia. | Expert opinion on drug metabolism & toxicology 20110501 |
| Mouse models of graft-versus-host disease: advances and limitations. | Disease models & mechanisms 20110501 |
| [Promoter methylation status of hPer3 gene in AML patients and the in vitro effect of decitabine on the status]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501 |
| c-JUN prevents methylation of p16(INK4a) (and Cdk6): the villain turned bodyguard. | Oncotarget 20110501 |
| [Reversal effect of 5-Aza-dc on cisplatin-resistance in human NSCLC cells in vitro]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110501 |
| A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors. | Oncogene 20110421 |
| Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. | International journal of cancer 20110415 |
| Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas. | Breast cancer research and treatment 20110401 |
| Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines. | International journal of andrology 20110401 |
| Decreased incidence of febrile episodes with antibiotic prophylaxis in the treatment of decitabine for myelodysplastic syndrome. | Leukemia research 20110401 |
| Aberrant methylation of the RIZ1 gene in myelodysplastic syndrome and acute myeloid leukemia. | Leukemia research 20110401 |
| Gene expression profiling of myelodysplastic CD34+ hematopoietic stem cells treated in vitro with decitabine. | Leukemia research 20110401 |
| Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial. | Annals of hematology 20110401 |
| Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway. | European journal of nuclear medicine and molecular imaging 20110401 |
| Epigenetic modification involved in benzene-induced apoptosis through regulating apoptosis-related genes expression. | Cell biology international 20110401 |
| Decitabine-induced apoptosis is derived by Puma and Noxa induction in chronic myeloid leukemia cell line as well as in PBL and is potentiated by SAHA. | Molecular and cellular biochemistry 20110401 |
| 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene. | The international journal of biochemistry & cell biology 20110401 |
| (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells. | Carcinogenesis 20110401 |
| Epigenetic regulation of the calcitonin gene-related peptide gene in trigeminal glia. | Cephalalgia : an international journal of headache 20110401 |
| Methylation status of T-lymphoma invasion and metastasis 1 promoter and its overexpression in colorectal cancer. | Human pathology 20110401 |
| Hypermethylation of hepatic glucokinase and L-type pyruvate kinase promoters in high-fat diet-induced obese rats. | Endocrinology 20110401 |
| GPR54 is a target for suppression of metastasis in endometrial cancer. | Molecular cancer therapeutics 20110401 |
| Possible involvement of loss of imprinting in immortalization of human fibroblasts. | International journal of oncology 20110401 |
| Quantitative assessment of AKAP12 promoter methylation in human prostate cancer using methylation-sensitive high-resolution melting: correlation with Gleason score. | Urology 20110401 |
| Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. | Epigenetics 20110401 |
| Interleukin-6 expression was regulated by epigenetic mechanisms in response to influenza virus infection or dsRNA treatment. | Molecular immunology 20110401 |
| Epigenetic regulation of somatic angiotensin-converting enzyme by DNA methylation and histone acetylation. | Epigenetics 20110401 |
| Epigenetic regulation in myelodysplastic syndromes: implications for therapy. | Expert opinion on investigational drugs 20110401 |
| Epigenetic modifications of the 35S promoter in cultured gentian cells. | Plant science : an international journal of experimental plant biology 20110401 |
| Abnormal methylation of histone deacetylase genes: implications on etiology and epigenetic therapy of astrocytomas. | Anticancer research 20110401 |
| Production of cloned calves by combination treatment of both donor cells and early cloned embryos with 5-aza-2/-deoxycytidine and trichostatin A. | Theriogenology 20110315 |
| Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110315 |
| DSC3 expression is regulated by p53, and methylation of DSC3 DNA is a prognostic marker in human colorectal cancer. | British journal of cancer 20110315 |
| MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. | Cancer research 20110315 |
| Epigenetics, microRNAs, and carcinogenesis: functional role of microRNA-137 in uveal melanoma. | Investigative ophthalmology & visual science 20110302 |
| In vitro cardiomyogenic potential of human amniotic fluid stem cells. | Journal of tissue engineering and regenerative medicine 20110301 |
| Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma. | Digestive diseases and sciences 20110301 |
| Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers. | Leukemia research 20110301 |
| Chronic exposure to cigarette smoke condensate in vitro induces epithelial to mesenchymal transition-like changes in human bronchial epithelial cells, BEAS-2B. | Toxicology in vitro : an international journal published in association with BIBRA 20110301 |
| Thioredoxin-binding protein-2 (TBP-2/VDUP1/TXNIP) regulates T-cell sensitivity to glucocorticoid during HTLV-I-induced transformation. | Leukemia 20110301 |
| Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia. | Epigenetics 20110301 |
| New nucleoside analogs for patients with hematological malignancies. | Expert opinion on investigational drugs 20110301 |
| Novel agents for the treatment of acute myeloid leukemia in the older patient. | Journal of the National Comprehensive Cancer Network : JNCCN 20110301 |
| Hypomethylating agents for urologic cancers. | Future oncology (London, England) 20110301 |
| [Inhibitory effect of 5-aza-2'-deoxycytidine combined with docetaxel on prostate cancer PC3 cells in vitro]. | Zhonghua nan ke xue = National journal of andrology 20110301 |
| Cardiomyocyte marker expression in a human lymphocyte cell line using mouse cardiomyocyte extract. | Human cell 20110301 |
| Epigenetics in cancer: what's the future? | Oncology (Williston Park, N.Y.) 20110301 |
| Effects of DNMT and MEK inhibitors on the expression of RECK, MMP-9, -2, uPA and VEGF in response to arsenite stimulation in human uroepithelial cells. | Toxicology letters 20110225 |
| Epigenetic inactivation of the RASSF10 candidate tumor suppressor gene is a frequent and an early event in gliomagenesis. | Oncogene 20110224 |
| Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a. | Toxicology and applied pharmacology 20110215 |
| Noncytotoxic differentiation treatment of renal cell cancer. | Cancer research 20110215 |
| Hypomethylating agents and other novel strategies in myelodysplastic syndromes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110210 |
| Irradiation, cisplatin, and 5-azacytidine upregulate cytomegalovirus promoter in tumors and muscles: implementation of non-invasive fluorescence imaging. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110201 |
| The transglutaminase 2 gene is aberrantly hypermethylated in glioma. | Journal of neuro-oncology 20110201 |
| Functional and epigenetic characterization of the KRT19 gene in renal cell neoplasms. | DNA and cell biology 20110201 |
| DNA methyltransferase inhibition may limit cancer cell growth by disrupting ribosome biogenesis. | Epigenetics 20110201 |
| Fused-core silica column ultra-performance liquid chromatography-ion trap tandem mass spectrometry for determination of global DNA methylation status. | Analytical biochemistry 20110201 |
| Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy. | Biochemical pharmacology 20110201 |
| Frequent gene hypermethylation in laryngeal cancer cell lines and the resistance to demethylation induction by plant polyphenols. | Toxicology in vitro : an international journal published in association with BIBRA 20110201 |
| Dual antitumour effect of 5-azacytidine by inducing a breakdown of resistance-mediating factors and epigenetic modulation. | Gut 20110201 |
| Successful resolution of acute myelogenous leukemia-associated hemophagocytic lymphohistiocytosis with decitabine. | Leukemia & lymphoma 20110201 |
| WNT5A expression is regulated by the status of its promoter methylation in leukaemia and can inhibit leukemic cell malignant proliferation. | Oncology reports 20110201 |
| Loss of DMBT1 expression in human prostate cancer and its correlation with clinical progressive features. | Urology 20110201 |
| Chromatin structure predicts epigenetic therapy responsiveness in sarcoma. | Molecular cancer therapeutics 20110201 |
| Aberrant methylation frequency of TNFRSF10C promoter in pancreatic cancer cell lines. | Hepatobiliary & pancreatic diseases international : HBPD INT 20110201 |
| DNA methylation changes following 5-azacitidine treatment in patients with myelodysplastic syndrome. | Journal of Korean medical science 20110201 |
| Epigenetic Silencing of ALDH1L1, a Metabolic Regulator of Cellular Proliferation, in Cancers. | Genes & cancer 20110201 |
| A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retina. | Vision research 20110128 |
| Silence of HIN-1 expression through methylation of its gene promoter in gastric cancer. | World journal of gastroenterology 20110128 |
| High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23). | Blood 20110120 |
| Effects of MEK and DNMT inhibitors on arsenic-treated human uroepithelial cells in relation to Cyclin-D1 and p16. | Toxicology letters 20110115 |
| Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c. | Biochemical and biophysical research communications 20110114 |
| Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation. | Mutation research 20110110 |
| A novel epigenetic phenotype associated with the most aggressive pathway of bladder tumor progression. | Journal of the National Cancer Institute 20110105 |
| Treatment with at homeopathic complex medication modulates mononuclear bone marrow cell differentiation. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| 3-Deazauridine enhances the antileukemic action of 5-aza-2'-deoxycytidine and targets drug-resistance due to deficiency in deoxycytidine kinase. | Leukemia research 20110101 |
| Demethylation of a nonpromoter cytosine-phosphate-guanine island in the aromatase gene may cause the aberrant up-regulation in endometriotic tissues. | Fertility and sterility 20110101 |
| Foetal nicotine exposure causes PKCε gene repression by promoter methylation in rat hearts. | Cardiovascular research 20110101 |
| Frequent epigenetic inactivation of Myocardin in human nasopharyngeal carcinoma. | Head & neck 20110101 |
| Demethylation of TMS1 gene sensitizes thyroid cancer cells to TRAIL-induced apoptosis. | The Journal of clinical endocrinology and metabolism 20110101 |
| Reduced methyl-CpG protein binding contributing to miR-184 expression in umbilical cord blood CD4+ T-cells. | Leukemia 20110101 |
| Epigenetic silencing of somatostatin in gastric cancer. | Digestive diseases and sciences 20110101 |
| Epigenetic regulation on the 5'-proximal CpG island of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B. | Microbes and infection 20110101 |
| Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A. | Differentiation; research in biological diversity 20110101 |
| siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)-dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures. | Experimental hematology 20110101 |
| Demethylation of E-cadherin gene in nasopharyngeal carcinoma could serve as a potential therapeutic strategy. | Journal of biochemistry 20110101 |
| Epigenetic regulation of glial fibrillary acidic protein by DNA methylation in human malignant gliomas. | Neuro-oncology 20110101 |
| Premature senescence induced by DNA demethylating agent (Decitabine) as therapeutic option for malignant pleural mesothelioma. | Lung cancer (Amsterdam, Netherlands) 20110101 |
| Epigenetic modification of RhoE expression in gastric cancer cells. | Oncology reports 20110101 |
| Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity. | Current medicinal chemistry 20110101 |
| Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors. | Journal of biomedicine & biotechnology 20110101 |
| Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies? | Journal of biomedicine & biotechnology 20110101 |
| Identification of novel DNA methylation inhibitors via a two-component reporter gene system. | Journal of biomedical science 20110101 |
| Epigenetic reprogramming of breast cancer cells with oocyte extracts. | Molecular cancer 20110101 |
| NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes. | Journal of the National Comprehensive Cancer Network : JNCCN 20110101 |
| Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay. | Journal of biomedicine & biotechnology 20110101 |
| Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel. | BMC cancer 20110101 |
| DNA methylation-mediated control of learning and memory. | Molecular brain 20110101 |
| Discovery pipeline for epigenetically deregulated miRNAs in cancer: integration of primary miRNA transcription. | BMC genomics 20110101 |
| Evaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaks. | Genome integrity 20110101 |
| Analysis of the ex vivo and in vivo antiretroviral activity of gemcitabine. | PloS one 20110101 |
| DNA methylation of the first exon is tightly linked to transcriptional silencing. | PloS one 20110101 |
| Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. | PloS one 20110101 |
| Functional characterization of Trip10 in cancer cell growth and survival. | Journal of biomedical science 20110101 |
| Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd+2 or As+3 transformed human urothelial cells. | Cancer cell international 20110101 |
| Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma. | BMC cancer 20110101 |
| Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis. | Molecular cancer 20110101 |
| The role of HDACs inhibitors in childhood and adolescence acute leukemias. | Journal of biomedicine & biotechnology 20110101 |
| Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice. | BMC cancer 20110101 |
| Genome-wide expression patterns associated with oncogenesis and sarcomatous transdifferentation of cholangiocarcinoma. | BMC cancer 20110101 |
| Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells. | BMC cancer 20110101 |
| ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer. | PloS one 20110101 |
| Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery. | PloS one 20110101 |
| Functional and sequence analysis of human neuroglobin gene promoter region. | Biochimica et biophysica acta 20110101 |
| Newly engineered magnetic erythrocytes for sustained and targeted delivery of anti-cancer therapeutic compounds. | PloS one 20110101 |
| Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia. | PloS one 20110101 |
| Induction of cyclooxygenase-2 expression by hepatitis B virus depends on demethylation-associated recruitment of transcription factors to the promoter. | Virology journal 20110101 |
| Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines. | PloS one 20110101 |
| Genome-wide assessment of imprinted expression in human cells. | Genome biology 20110101 |
| [Progress in research on DNA methylation and laryngeal carcinoma]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20110101 |
| Future perspectives in melanoma research. Meeting report from the 'Melanoma Research: a bridge Naples-USA. Naples, December 6th-7th 2010'. | Journal of translational medicine 20110101 |
| Continuous and low-energy 125I seed irradiation changes DNA methyltransferases expression patterns and inhibits pancreatic cancer tumor growth. | Journal of experimental & clinical cancer research : CR 20110101 |
| Proximity ligation in situ assay for monitoring the global DNA methylation in cells. | BMC biotechnology 20110101 |
| Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties. | Journal of experimental & clinical cancer research : CR 20110101 |
| Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells. | BMC genomics 20110101 |
| Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer. | Molecular cancer 20110101 |
| LINE-1 hypomethylation during primary colon cancer progression. | PloS one 20110101 |
| Epigenetics, spermatogenesis and male infertility. | Mutation research 20110101 |
| Epigenetic regulation of cancer-associated genes in ovarian cancer. | International journal of molecular sciences 20110101 |
| Epigenetic inactivation of the miR-124-1 in haematological malignancies. | PloS one 20110101 |
| CpG island methylation in colorectal cancer: past, present and future. | Pathology research international 20110101 |
| Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons. | PloS one 20110101 |
| Cardiac differentiation of pluripotent stem cells. | Stem cells international 20110101 |
| Homeobox gene Rhox5 is regulated by epigenetic mechanisms in cancer and stem cells and promotes cancer growth. | Molecular cancer 20110101 |
| Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications. | BMC medicine 20110101 |
| Methylation levels of the 'long interspersed nucleotide element-1' repetitive sequences predict survival of melanoma patients. | Journal of translational medicine 20110101 |
| PKC isoforms interact with and phosphorylate DNMT1. | BMC biology 20110101 |
| 5-azacytidine in chronic myelomonocytic leukemia: case report and review of literature. | Mediterranean journal of hematology and infectious diseases 20110101 |
| Interpreting clinical assays for histone deacetylase inhibitors. | Cancer management and research 20110101 |
| Myelodysplastic syndrome and histone deacetylase inhibitors: 'to be or not to be acetylated'? | Journal of biomedicine & biotechnology 20110101 |
| Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1. | PloS one 20110101 |
| Aberrant methylation of N-methyl-D-aspartate receptor type 2B (NMDAR2B) in non-small cell carcinoma. | BMC cancer 20110101 |
| Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. | BMC cancer 20110101 |
| Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences. | BMC genomics 20110101 |
| Zeranol down-regulates p53 expression in primary cultured human breast cancer epithelial cells through epigenetic modification. | International journal of molecular sciences 20110101 |
| Changes in global gene expression in response to chemical and genetic perturbation of chromatin structure. | PloS one 20110101 |
| Potential utility of natural products as regulators of breast cancer-associated aromatase promoters. | Reproductive biology and endocrinology : RB&E 20110101 |
| Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis. | PloS one 20110101 |
| Identification and functional analysis of epigenetically silenced microRNAs in colorectal cancer cells. | PloS one 20110101 |
| A DNMT3B alternatively spliced exon and encoded peptide are novel biomarkers of human pluripotent stem cells. | PloS one 20110101 |
| Thalassemia and venous thromboembolism. | Mediterranean journal of hematology and infectious diseases 20110101 |
| Securinine, a myeloid differentiation agent with therapeutic potential for AML. | PloS one 20110101 |
| Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells. | PloS one 20110101 |
| MAGE-C2/CT10 protein expression is an independent predictor of recurrence in prostate cancer. | PloS one 20110101 |
| Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia. | PloS one 20110101 |
| Therapeutic strategies to enhance the anticancer efficacy of histone deacetylase inhibitors. | Journal of biomedicine & biotechnology 20110101 |
| Epigenetic silencing of erythropoietin in human cancers. | Genes & cancer 20110101 |
| Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells. | PloS one 20110101 |
| Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer. | Molecular cancer 20110101 |
| Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation. | PloS one 20110101 |
| Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression. | Breast cancer research : BCR 20110101 |
| Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors. | BMC cancer 20110101 |
| Epigenetic therapy for breast cancer. | International journal of molecular sciences 20110101 |
| DNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells. | Molecular medicine reports 20110101 |
| Mechanisms of resistance to decitabine in the myelodysplastic syndrome. | PloS one 20110101 |
| Epigenetic regulation of caloric restriction in aging. | BMC medicine 20110101 |
| Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells. | PloS one 20110101 |
| Current findings for recurring mutations in acute myeloid leukemia. | Journal of hematology & oncology 20110101 |
| Helios expression is a marker of T cell activation and proliferation. | PloS one 20110101 |
| The tumour suppressor SOX11 is associated with improved survival among high grade epithelial ovarian cancers and is regulated by reversible promoter methylation. | BMC cancer 20110101 |
| Systematic in-vitro evaluation of the NCI/NIH Developmental Therapeutics Program Approved Oncology Drug Set for the identification of a candidate drug repertoire for MLL-rearranged leukemia. | OncoTargets and therapy 20110101 |
| Epigenetic regulation of microRNA genes and the role of miR-34b in cell invasion and motility in human melanoma. | PloS one 20110101 |
| Generation of reactive oxygen species during apoptosis induced by DNA-damaging agents and/or histone deacetylase inhibitors. | Oxidative medicine and cellular longevity 20110101 |
| Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor. | Breast cancer research : BCR 20110101 |
| MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma. | Molecular cancer 20110101 |
| Promoting illiteracy in epigenetics: an emerging therapeutic strategy. | Current chemical genomics 20110101 |
| Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumors. | Cell adhesion & migration 20110101 |
| GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells. | PloS one 20110101 |
| Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma. | PloS one 20110101 |
| Systemic vasculitis with prolonged pyrexia, recurrent facial urticaria, skin nodules, pleural effusions and venous thrombosis: an unusual presentation of an uncommon disease. | German medical science : GMS e-journal 20110101 |
| Promoter hypermethylation mediated downregulation of FBP1 in human hepatocellular carcinoma and colon cancer. | PloS one 20110101 |
| Paracrine molecules of mesenchymal stem cells for hematopoietic stem cell niche. | Bone marrow research 20110101 |
| An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells. | Molecular cancer 20110101 |
| Loss of interferon regulatory factor 5 (IRF5) expression in human ductal carcinoma correlates with disease stage and contributes to metastasis. | Breast cancer research : BCR 20110101 |
| Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway. | Journal of translational medicine 20110101 |
| Integrated epigenetics of human breast cancer: synoptic investigation of targeted genes, microRNAs and proteins upon demethylation treatment. | PloS one 20110101 |
| Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms. | Journal of translational medicine 20110101 |
| Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays. | BMC molecular biology 20110101 |
| Uses of cardiomyocytes generated from induced pluripotent stem cells. | Stem cell research & therapy 20110101 |
| Therapy-related myeloid malignancies in myeloma. | Mediterranean journal of hematology and infectious diseases 20110101 |
| Genome-wide differential gene expression in immortalized DF-1 chicken embryo fibroblast cell line. | BMC genomics 20110101 |
| miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells. | Breast cancer research : BCR 20110101 |
| Analysis of CpG methylation sites and CGI among human papillomavirus DNA genomes. | BMC genomics 20110101 |
| Decreased expression of 17β-hydroxysteroid dehydrogenase type 1 is associated with DNA hypermethylation in colorectal cancer located in the proximal colon. | BMC cancer 20110101 |
| Epigenetics in prostate cancer. | Prostate cancer 20110101 |
| Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses. | PloS one 20110101 |
| DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma. | Genome medicine 20110101 |
| Pseudo differentiation syndrome. | Mediterranean journal of hematology and infectious diseases 20110101 |
| Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. | Clinical epigenetics 20110101 |
| Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia. | Journal of blood medicine 20110101 |
| Romidepsin in the treatment of cutaneous T-cell lymphoma. | Journal of blood medicine 20110101 |
| Development of an oral form of azacytidine: 2'3'5'triacetyl-5-azacytidine. | Chemotherapy research and practice 20110101 |
| Epigenomics of ovarian cancer and its chemoprevention. | Frontiers in genetics 20110101 |
| The Beginning of the Road for Non-Coding RNAs in Normal Hematopoiesis and Hematologic Malignancies. | Frontiers in genetics 20110101 |
| Methylation of secreted frizzled related protein gene in acute leukemia patients in China. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
| Ribavirin restores ESR1 gene expression and tamoxifen sensitivity in ESR1 negative breast cancer cell lines. | Clinical epigenetics 20110101 |
| Suffocating cancer: hypoxia-associated epimutations as targets for cancer therapy. | Clinical epigenetics 20110101 |
| Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers. | Frontiers in oncology 20110101 |
| Ocular manifestations and pathology of adult T-cell leukemia/lymphoma associated with human T-lymphotropic virus type 1. | Rare tumors 20101231 |
| Sequential treatment of CD34+ cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells. | Blood 20101223 |
| [Myeloproliferative/myelodysplastic syndromes]. | La Revue du praticien 20101220 |
| Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis. | Blood 20101202 |
| DNA methylation and carcinogenesis of PRDM5 in cervical cancer. | Journal of cancer research and clinical oncology 20101201 |
| Expression, epigenetic regulation, and humoral immunogenicity of cancer-testis antigens in chronic myeloid leukemia. | Leukemia research 20101201 |
| Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect. | Carcinogenesis 20101201 |
| Decitabine in myelodysplastic syndromes and chronic myelomonocytic leukemia: Argentinian/South Korean multi-institutional clinical experience. | Leukemia & lymphoma 20101201 |
| Prodrugs of aza nucleosides based on proton transfer reaction. | Journal of computer-aided molecular design 20101201 |
| Transcriptional repression of DLEC1 associates with the depth of tumor invasion in oral squamous cell carcinoma. | Oral oncology 20101201 |
| Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101201 |
| Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms. | Hepatology (Baltimore, Md.) 20101201 |
| Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancer. | The American journal of pathology 20101201 |
| Pharmacologic induction of fetal hemoglobin production. | Hematology/oncology clinics of North America 20101201 |
| Analysis of genome-wide methylation and gene expression induced by 5-aza-2'-deoxycytidine identifies BCL2L10 as a frequent methylation target in acute myeloid leukemia. | Leukemia & lymphoma 20101201 |
| Histone deacetylase inhibitors in Hodgkin lymphoma. | Investigational new drugs 20101201 |
| Has there been progress in the treatment of older patients with acute myeloid leukemia? | Best practice & research. Clinical haematology 20101201 |
| The DAC system and associations with acute leukemias and myelodysplastic syndromes. | Investigational new drugs 20101201 |
| Aberrant methylation of heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer. | Anticancer research 20101201 |
| Alphabet soup: RAEB, HMA, DOE, and AFOP. | Medicine and health, Rhode Island 20101201 |
| Economic analysis of decitabine versus best supportive care in the treatment of intermediate- and high-risk myelodysplastic syndromes from a US payer perspective. | Clinical therapeutics 20101201 |
| Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells. | Cell death & disease 20101201 |
| Cytosine methyltransferases as tumor markers. | Current genomics 20101201 |
| Hypoexpression and epigenetic regulation of candidate tumor suppressor gene CADM-2 in human prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101115 |
| Epigenetic silencing of beta-spectrin, a TGF-beta signaling/scaffolding protein in a human cancer stem cell disorder: Beckwith-Wiedemann syndrome. | The Journal of biological chemistry 20101112 |
| Targeted methylation of CMV and E1A viral promoters. | Biochemical and biophysical research communications 20101112 |
| Epigenetic silencing of lysyl oxidase-like-1 through DNA hypermethylation in an autosomal recessive cutis laxa case. | The Journal of investigative dermatology 20101101 |
| Epigenetic regulation of miR-196b expression in gastric cancer. | Genes, chromosomes & cancer 20101101 |
| Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications. | Journal of hepatology 20101101 |
| Promoter hypermethylation of progesterone receptor isoform B (PR-B) in adenomyosis and its rectification by a histone deacetylase inhibitor and a demethylation agent. | Reproductive sciences (Thousand Oaks, Calif.) 20101101 |
| Decitabine increases fetal hemoglobin in Papio anubis by increasing γ-globin gene transcription. | Experimental hematology 20101101 |
| Aberrant demethylation of the recoverin gene is involved in the aberrant expression of recoverin in cancer cells. | Experimental dermatology 20101101 |
| The effect of DNA methylation inhibitor 5-Aza-2'-deoxycytidine on human endometrial stromal cells. | Human reproduction (Oxford, England) 20101101 |
| Loss of reelin expression in breast cancer is epigenetically controlled and associated with poor prognosis. | The American journal of pathology 20101101 |
| Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines. | Oncology reports 20101101 |
| Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice. | The American journal of pathology 20101101 |
| Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. | Nature neuroscience 20101101 |
| Protein tyrosine phosphatase receptor type {gamma} is a functional tumor suppressor gene specifically downregulated in chronic myeloid leukemia. | Cancer research 20101101 |
| Claudin-7 down-regulation is an important feature in oral squamous cell carcinoma. | Histopathology 20101101 |
| Altered DNA methylation in leukocytes with trisomy 21. | PLoS genetics 20101101 |
| [Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101 |
| Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription. | Oncogene 20101028 |
| The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers. | International journal of cancer 20101015 |
| Promoter hypomethylation and upregulation of trefoil factors in prostate cancer. | International journal of cancer 20101015 |
| Cell cycle-dependent accumulation of histone H3.3 and euchromatic histone modifications in pericentromeric heterochromatin in response to a decrease in DNA methylation levels. | Experimental cell research 20101015 |
| Epigenetic influences of low-dose bisphenol A in primary human breast epithelial cells. | Toxicology and applied pharmacology 20101015 |
| Epigenetic inactivation and tumor suppressor activity of HAI-2/SPINT2 in gastric cancer. | International journal of cancer 20101001 |
| Downregulation of tapasin expression in primary human oral squamous cell carcinoma: association with clinical outcome. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20101001 |
| Epigenetically altered wound healing in keloid fibroblasts. | The Journal of investigative dermatology 20101001 |
| Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study. | Pediatric blood & cancer 20101001 |
| Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes. | Molecular pharmacology 20101001 |
| Epigenetic reprogramming of host genes in viral and microbial pathogenesis. | Trends in microbiology 20101001 |
| Loss of WW domain-containing oxidoreductase expression in the progression and development of gastric carcinoma: clinical and histopathologic correlations. | Virchows Archiv : an international journal of pathology 20101001 |
| Myelodysplastic syndromes in older adults. | Clinical journal of oncology nursing 20101001 |
| [Expression, genetic and epigenetic alterations of LTF gene in nasopharyngeal carcinoma cell lines]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001 |
| Absence of Metallothionein 3 Expression in Breast Cancer is a Rare, But Favorable Marker of Outcome that is Under Epigenetic Control. | Toxicological and environmental chemistry 20101001 |
| Regeneration and DNA demethylation do not trigger PDX-1 expression in rat hepatocytes. | World journal of biological chemistry 20100926 |
| DNA methylation of the Trip10 promoter accelerates mesenchymal stem cell lineage determination. | Biochemical and biophysical research communications 20100924 |
| Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis. | Oncogene 20100916 |
| Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells. | Oncogene 20100916 |
| WNT5A antagonizes WNT/β-catenin signaling and is frequently silenced by promoter CpG methylation in esophageal squamous cell carcinoma. | Cancer biology & therapy 20100915 |
| Effect of 5-aza-2-deoxycytidine microinjecting into hippocampus and prelimbic cortex on acquisition and retrieval of cocaine-induced place preference in C57BL/6 mice. | European journal of pharmacology 20100910 |
| miR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer. | International journal of cancer 20100901 |
| Demethylating agent 5-aza-2-deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents. | Molecular and cellular biochemistry 20100901 |
| Epigenetic and genetic silencing of CHFR in esophageal adenocarcinomas. | Cancer 20100901 |
| A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer. | Cancer 20100901 |
| Exploiting drug repositioning for discovery of a novel HIV combination therapy. | Journal of virology 20100901 |
| Therapeutic options for patients with myelofibrosis in blast phase. | Leukemia research 20100901 |
| The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer. | Carcinogenesis 20100901 |
| Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer. | Molecular cancer research : MCR 20100901 |
| Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation. | Cancer research 20100901 |
| Modulation of embryo-forming capacity in culture through the expression of Brassica genes involved in the regulation of the shoot apical meristem. | Journal of experimental botany 20100901 |
| The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation. | The Journal of biological chemistry 20100820 |
| Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. | Blood 20100819 |
| Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. | Epigenetics 20100816 |
| Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling. | Biochemical pharmacology 20100815 |
| Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy. | Cancer 20100815 |
| Chronic prenatal hypoxia induces epigenetic programming of PKC{epsilon} gene repression in rat hearts. | Circulation research 20100806 |
| Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer. | Breast cancer research and treatment 20100801 |
| Identification of aberrant promoter hypomethylation of HOXA10 in ovarian cancer. | Journal of cancer research and clinical oncology 20100801 |
| Functional modulation of IGF-binding protein-3 expression in melanoma. | The Journal of investigative dermatology 20100801 |
| Clinical advances in hypomethylating agents targeting epigenetic pathways. | Current cancer drug targets 20100801 |
| Pharmacotherapy of myelodysplastic syndromes. | Expert opinion on pharmacotherapy 20100801 |
| Therapy with azanucleosides for myelodysplastic syndromes. | Nature reviews. Clinical oncology 20100801 |
| Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesothelioma. | Oncology reports 20100801 |
| Aberrant promoter methylation of DLEC1, a critical 3p22 tumor suppressor for renal cell carcinoma, is associated with more advanced tumor stage. | The Journal of urology 20100801 |
| Validation of a novel statistical model for assessing the synergy of combined-agent cancer chemoprevention. | Cancer prevention research (Philadelphia, Pa.) 20100801 |
| Identification of novel methylation markers in hepatocellular carcinoma using a methylation array. | Journal of Korean medical science 20100801 |
| Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression. | Molecular cancer therapeutics 20100801 |
| Fetal globin gene inducers: novel agents and new potential. | Annals of the New York Academy of Sciences 20100801 |
| [Study on promoter methylation status of E-cadherin gene in nasopharyngeal carcinoma cell lines]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20100801 |
| Current and future management options for myelodysplastic syndromes. | Drugs 20100730 |
| Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. | Cancer research 20100715 |
| Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100715 |
| MAD2 downregulation in hypoxia is independent of promoter hypermethylation. | Cell cycle (Georgetown, Tex.) 20100715 |
| The functional significance of microRNA-145 in prostate cancer. | British journal of cancer 20100713 |
| In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia. | Blood 20100708 |
| Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers. | World journal of gastroenterology 20100707 |
| Rapid determination of AKAP12 promoter methylation levels in peripheral blood using methylation-sensitive high resolution melting (MS-HRM) analysis: application in colorectal cancer. | Clinica chimica acta; international journal of clinical chemistry 20100704 |
| Changes in chromatin structure and methylation of the human interleukin-1beta gene during monopoiesis. | Immunology 20100701 |
| Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. | Pancreas 20100701 |
| Establishment and characterization of multi-drug resistant, prostate carcinoma-initiating stem-like cells from human prostate cancer cell lines 22RV1. | Molecular and cellular biochemistry 20100701 |
| Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20-methylcholanthrene. | Journal of cellular physiology 20100701 |
| Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b. | Carcinogenesis 20100701 |
| The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells. | Leukemia research 20100701 |
| Possible involvement of DNA methylation in NKCC1 gene expression during postnatal development and in response to ischemia. | Journal of neurochemistry 20100701 |
| Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation. | British journal of haematology 20100701 |
| Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells. | The American journal of pathology 20100701 |
| DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae. | Cancer science 20100701 |
| Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy. | Molecular cancer research : MCR 20100701 |
| Frequent epigenetic inactivation of deleted in lung and esophageal cancer 1 gene by promoter methylation in non-small-cell lung cancer. | Clinical lung cancer 20100701 |
| Screening for methylation-silenced genes in acute myeloid leukemia HL-60 cell line by a quantitative proteomic approach. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100701 |
| Promoter hypomethylation contributes to the expression of MUC3A in cancer cells. | Biochemical and biophysical research communications 20100625 |
| Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. | Circulation 20100622 |
| DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcription factor binding. | The Journal of biological chemistry 20100618 |
| Downregulation of WIF-1 by hypermethylation in astrocytomas. | Acta biochimica et biophysica Sinica 20100615 |
| Epigenetic mechanisms regulating CYP19 transcription in human breast adipose fibroblasts. | Molecular and cellular endocrinology 20100610 |
| Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting. | Blood 20100610 |
| Methylation of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression. | Toxicology letters 20100602 |
| 5-Aza-2'-deoxycytidine is a potent inhibitor of DNA methyltransferase 3B and induces apoptosis in human endometrial cancer cell lines with the up-regulation of hMLH1. | Medical oncology (Northwood, London, England) 20100601 |
| Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas. | International journal of cancer 20100601 |
| Induction of apoptosis of non-small cell lung cancer by a methylated oligonucleotide targeting survivin gene. | Cancer gene therapy 20100601 |
| Epigenetic therapy in myelodysplastic syndromes. | European journal of haematology 20100601 |
| Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma. | Carcinogenesis 20100601 |
| Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue. | Diabetologia 20100601 |
| Quantitative assessment of AKAP12 promoter methylation in colorectal cancer using methylation-sensitive high resolution melting: Correlation with Duke's stage. | Cancer biology & therapy 20100601 |
| Long-term genistein treatment of MCF-7 cells decreases acetylated histone 3 expression and alters growth responses to mitogens and histone deacetylase inhibitors. | The Journal of steroid biochemistry and molecular biology 20100601 |
| Frequent alterations of the candidate genes hMLH1, ITGA9 and RBSP3 in early dysplastic lesions of head and neck: clinical and prognostic significance. | Cancer science 20100601 |
| DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines. | Journal of biotechnology 20100601 |
| Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells. | Cancer research 20100601 |
| Development of therapeutic agents for older patients with acute myelogenous leukemia. | Current opinion in investigational drugs (London, England : 2000) 20100601 |
| Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus. | Molecular cancer therapeutics 20100601 |
| Feasibility of therapy with hypomethylating agents in patients with renal insufficiency. | Clinical lymphoma, myeloma & leukemia 20100601 |
| Epigenetic silencing of cell cycle regulatory genes during 3-methylcholanthrene and diethylnitrosamine-induced multistep rat lung cancer. | Molecular carcinogenesis 20100601 |
| CpG island methylator phenotype involving chromosome 3p confers an increased risk of non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100601 |
| An update on the treatment of myelodysplastic syndromes. | Clinical journal of oncology nursing 20100601 |
| Dosage-sensitive function of retinoblastoma related and convergent epigenetic control are required during the Arabidopsis life cycle. | PLoS genetics 20100601 |
| Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA. | PLoS pathogens 20100601 |
| Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells. | Anticancer research 20100601 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20100601 |
| Effect of 5-aza-2'-deoxycytidine on immune-associated proteins in exosomes from hepatoma. | World journal of gastroenterology 20100521 |
| The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma. | Oncogene 20100520 |
| [The relationship between the TSLC1 silencing and DNA methylation in human lung cancer cells]. | Zhongguo fei ai za zhi = Chinese journal of lung cancer 20100520 |
| Methylation of a single intronic CpG mediates expression silencing of the PMP24 gene in prostate cancer. | The Prostate 20100515 |
| Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene. | Experimental cell research 20100515 |
| Virus-specific cytotoxic CD4+ T cells for the treatment of EBV-related tumors. | Journal of immunology (Baltimore, Md. : 1950) 20100515 |
| miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. | Carcinogenesis 20100501 |
| FOXE1 is a target for aberrant methylation in cutaneous squamous cell carcinoma. | The British journal of dermatology 20100501 |
| Role of histone modifications and DNA methylation in the regulation of O6-methylguanine-DNA methyltransferase gene expression in human stomach cancer cells. | Cancer investigation 20100501 |
| Generation of antigen-presenting cells from tumor-infiltrated CD11b myeloid cells with DNA demethylating agent 5-aza-2'-deoxycytidine. | Cancer immunology, immunotherapy : CII 20100501 |
| Neutrophilic eccrine hidradenitis associated with decitabine. | Leukemia research 20100501 |
| Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis. | Carcinogenesis 20100501 |
| Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation. | Genes, chromosomes & cancer 20100501 |
| Aberrant methylation impairs low density lipoprotein receptor-related protein 1B tumor suppressor function in gastric cancer. | Genes, chromosomes & cancer 20100501 |
| Epigenetic repression of E-cadherin by human papillomavirus 16 E7 protein. | Carcinogenesis 20100501 |
| Epigenetically regulated clonal heritability of CTA expression profiles in human melanoma. | Journal of cellular physiology 20100501 |
| TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer. | Genes, chromosomes & cancer 20100501 |
| 5-Aza-2'-deoxycytidine treatment induces skeletal myogenic differentiation of mouse dental pulp stem cells. | Archives of oral biology 20100501 |
| Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells. | International journal of oncology 20100501 |
| Frequent inactivation of hSRBC in ovarian cancers by promoter CpG island hypermethylation. | Acta obstetricia et gynecologica Scandinavica 20100501 |
| [Epigenetic therapy in myelodysplastic syndromes (MDS). Treatment with DNA methyltransferase inhibitors]. | Pharmazie in unserer Zeit 20100501 |
| Advances in the management of acute myeloid leukemia in older adult patients. | Oncology nursing forum 20100501 |
| S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. | Molecular cancer therapeutics 20100501 |
| Enhancement of cardiomyocyte differentiation from human embryonic stem cells. | Science China. Life sciences 20100501 |
| Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer. | The Journal of biological chemistry 20100416 |
| Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines. | Toxicology letters 20100415 |
| Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML. | Blood 20100415 |
| The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100415 |
| Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells. | Breast cancer research and treatment 20100401 |
| CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors. | Breast cancer research and treatment 20100401 |
| Effects of decitabine on the expression of selected endogenous control genes in human breast cancer cells. | Molecular and cellular probes 20100401 |
| Increased CXCR4 expression in AsPC1 pancreatic carcinoma cells with RNA interference-mediated knockdown of DNMT1 and DNMT3B. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100401 |
| Direct and transgenerational impact on Daphnia magna of chemicals with a known effect on DNA methylation. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100401 |
| Epigenetic mediated transcriptional activation of PARP-1 participates in silica-associated malignant transformation of human bronchial epithelial cells. | Toxicology letters 20100401 |
| Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas. | Neuropathology and applied neurobiology 20100401 |
| PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells. | Pigment cell & melanoma research 20100401 |
| Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma. | International journal of oncology 20100401 |
| Identification of hypermethylated genes associated with cisplatin resistance in human cancers. | Cancer research 20100401 |
| Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6. | Molecular cancer research : MCR 20100401 |
| Epigenetic changes in the myelodysplastic syndrome. | Hematology/oncology clinics of North America 20100401 |
| Practical recommendations for hypomethylating agent therapy of patients with myelodysplastic syndromes. | Hematology/oncology clinics of North America 20100401 |
| Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer. | PLoS genetics 20100401 |
| [No correlation between the sensitivity to 5-aza-dC and the global DNA methylation level in hepatocellular carcinoma cells]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100401 |
| Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer. | Journal of gastroenterology and hepatology 20100401 |
| The expression of survivin and its related genes in adipocyte-derived stem cell by demethylation. | Korean journal of anesthesiology 20100401 |
| [Synergistic effect of DNA methylation inhibitor and histone deacetylase inhibitor on RASSF1A gene expression in U266 cells.]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20100401 |
| Differential epigenetic regulation of BDNF and NT-3 genes by trichostatin A and 5-aza-2'-deoxycytidine in Neuro-2a cells. | Biochemical and biophysical research communications 20100326 |
| The imprinted gene PEG3 inhibits Wnt signaling and regulates glioma growth. | The Journal of biological chemistry 20100312 |
| RA induces the neural-like cells generated from epigenetic modified NIH/3T3 cells. | Molecular biology reports 20100301 |
| IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. | Carcinogenesis 20100301 |
| 5-Aza-2'-deoxycytidine sensitizes busulfan-resistant myeloid leukemia cells by regulating expression of genes involved in cell cycle checkpoint and apoptosis. | Leukemia research 20100301 |
| Epidermal growth factor-containing fibulin-like extracellular matrix protein 1, EFEMP1, a novel tumor-suppressor gene detected in hepatocellular carcinoma using double combination array analysis. | Annals of surgical oncology 20100301 |
| Killer cell immunoglobulin-like receptor expression induction on neonatal CD8(+) T cells in vitro and following congenital infection with Trypanosoma cruzi. | Immunology 20100301 |
| Maintenance therapy in acute myeloid leukemia revisited: will new agents rekindle an old interest? | Current opinion in hematology 20100301 |
| Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer. | Laboratory investigation; a journal of technical methods and pathology 20100301 |
| DNA methylation profiles of organic anion transporting polypeptide 1B3 in cancer cell lines. | Pharmaceutical research 20100301 |
| DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target. | Cancer research 20100301 |
| The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice. | Regenerative medicine 20100301 |
| Valproic acid in the complex therapy of malignant tumors. | Current drug targets 20100301 |
| Antineoplastic effects of decitabine, an inhibitor of DNA promoter methylation, in adrenocortical carcinoma cells. | Archives of surgery (Chicago, Ill. : 1960) 20100301 |
| Expression of glutathione S-transferase M2 in stage I/II non-small cell lung cancer and alleviation of DNA damage exposure to benzo[a]pyrene. | Toxicology letters 20100215 |
| Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells. | Cancer research 20100215 |
| Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors. | Cancer research 20100215 |
| X-linked ectodermal dysplasia receptor is downregulated in breast cancer via promoter methylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100215 |
| [The methylation analysis of EMP3 and PCDH-gamma-A11 gene in human glioma]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20100215 |
| CTCF is a DNA methylation-sensitive positive regulator of the INK/ARF locus. | Biochemical and biophysical research communications 20100205 |
| Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli. | DNA repair 20100204 |
| Sox17, the canonical Wnt antagonist, is epigenetically inactivated by promoter methylation in human breast cancer. | Breast cancer research and treatment 20100201 |
| Aberrant DNA methylation of integrin alpha4: a potential novel role for metastasis of cholangiocarcinoma. | Journal of cancer research and clinical oncology 20100201 |
| Preclinical antileukemia activity of JNJ-26481585, a potent second-generation histone deacetylase inhibitor. | Leukemia research 20100201 |
| 5-azacitidine prolongs overall survival in patients with myelodysplastic syndrome--a systematic review and meta-analysis. | Haematologica 20100201 |
| Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100201 |
| Inhibition of methylation decreases osteoblast differentiation via a non-DNA-dependent methylation mechanism. | Bone 20100201 |
| Hepatitis B virus X protein overcomes the growth-inhibitory potential of retinoic acid by downregulating retinoic acid receptor-beta2 expression via DNA methylation. | The Journal of general virology 20100201 |
| The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells. | Toxicology letters 20100201 |
| Decitabine versus 5-azacitidine for the treatment of myelodysplastic syndrome: adjusted indirect meta-analysis. | Haematologica 20100201 |
| Epigenetic therapies for chemoresensitization of epithelial ovarian cancer. | Gynecologic oncology 20100201 |
| Epigenetic regulation of the non-canonical Wnt pathway in acute myeloid leukemia. | Cancer science 20100201 |
| Resistance to 5-aza-2'-deoxycytidine in genic regions compared to non-genic repetitive sequences. | The Journal of reproduction and development 20100201 |
| Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201 |
| Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines. | Leukemia & lymphoma 20100201 |
| DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201 |
| DNA methylation and its involvement in carboxylesterase 1A1 (CES1A1) gene expression. | Xenobiotica; the fate of foreign compounds in biological systems 20100201 |
| Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation. | The FEBS journal 20100201 |
| Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100201 |
| Tissue factor pathway inhibitor 2 (TFPI2) is frequently silenced by aberrant promoter hypermethylation in gastric cancer. | Cancer genetics and cytogenetics 20100201 |
| Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth. | Molecular cancer therapeutics 20100201 |
| Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors. | Epigenomics 20100201 |
| Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition. | Oncogene 20100128 |
| Immune dysregulation in myelodysplastic syndrome. | Hematology reports 20100126 |
| DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells. | Experimental cell research 20100115 |
| Efficient readout of posttranslational codes on the 50-residue tail of histone H3 by high-resolution MS/MS. | Analytical biochemistry 20100115 |
| DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection. | Analytical biochemistry 20100115 |
| Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene. | The Journal of biological chemistry 20100115 |
| Methylation induced gene silencing of HtrA3 in smoking-related lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100115 |
| SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis. | Cancer research 20100115 |
| Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia. | Blood 20100114 |
| DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences. | Proceedings of the National Academy of Sciences of the United States of America 20100105 |
| Frequent methylation of RASSF1A in synovial sarcoma and the anti-tumor effects of 5-aza-2'-deoxycytidine against synovial sarcoma cell lines. | Journal of cancer research and clinical oncology 20100101 |
| Incorporating novel agents in the treatment of myelodysplastic syndromes. | Leukemia research 20100101 |
| Tumor necrosis factor-alpha decreases sarcoplasmic reticulum Ca2+-ATPase expressions via the promoter methylation in cardiomyocytes. | Critical care medicine 20100101 |
| Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer. | Human pathology 20100101 |
| Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection. | Molecular reproduction and development 20100101 |
| Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100101 |
| Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation. | British journal of haematology 20100101 |
| Combination PPARgamma and RXR Agonist Treatment in Melanoma Cells: Functional Importance of S100A2. | PPAR research 20100101 |
| Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer. | Cancer 20100101 |
| 5'-AZA induces Ngn3 expression and endocrine differentiation in the PANC-1 human ductal cell line. | Biochemical and biophysical research communications 20100101 |
| Cystatin M expression is reduced in gastric carcinoma and is associated with promoter hypermethylation. | Biochemical and biophysical research communications 20100101 |
| Decitabine in the treatment of myelodysplastic syndromes. | Expert review of anticancer therapy 20100101 |
| [Effect of 5-Aza-CdR on expression and methylation of E-cadherin gene in human colon carcinoma cells]. | Chinese journal of cancer 20100101 |
| Multifactorial regulation of E-cadherin expression: an integrative study. | Molecular cancer therapeutics 20100101 |
| Myelodysplastic syndromes. | Annual review of medicine 20100101 |
| Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice. | PloS one 20100101 |
| Decitabine. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101 |
| Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells. | PloS one 20100101 |
| Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number. | PloS one 20100101 |
| Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells. | BMC molecular biology 20100101 |
| Simultaneous CXCL12 and ESR1 CpG island hypermethylation correlates with poor prognosis in sporadic breast cancer. | BMC cancer 20100101 |
| Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy. | Journal of translational medicine 20100101 |
| A comparison of azacitidine and decitabine activities in acute myeloid leukemia cell lines. | PloS one 20100101 |
| Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents. | Journal of hematology & oncology 20100101 |
| Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. | BMC cancer 20100101 |
| Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma. | BMC medical genomics 20100101 |
| Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies. | Breast cancer research : BCR 20100101 |
| Osteopontin regulates human glioma cell invasiveness and tumor growth in mice. | Neuro-oncology 20100101 |
| DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer. | European journal of medical research 20100101 |
| A systems biology approach to invasive behavior: comparing cancer metastasis and suburban sprawl development. | BMC research notes 20100101 |
| A genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers. | Molecular cancer 20100101 |
| Influence of genetic background and tissue types on global DNA methylation patterns. | PloS one 20100101 |
| Elevated osteopontin levels in metastatic melanoma correlate with epigenetic silencing of breast cancer metastasis suppressor 1. | Oncology 20100101 |
| Genetic and epigenetic somatic alterations in head and neck squamous cell carcinomas are globally coordinated but not locally targeted. | PloS one 20100101 |
| BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas. | PloS one 20100101 |
| Methylation of the SPARC gene promoter and its clinical implication in pancreatic cancer. | Journal of experimental & clinical cancer research : CR 20100101 |
| Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in patients with myelodysplastic syndromes. | Clinical advances in hematology & oncology : H&O 20100101 |
| Circadian rhythm and its role in malignancy. | Journal of circadian rhythms 20100101 |
| Replication independent DNA double-strand break retention may prevent genomic instability. | Molecular cancer 20100101 |
| Rapid selection and proliferation of CD133+ cells from cancer cell lines: chemotherapeutic implications. | PloS one 20100101 |
| CD7 in acute myeloid leukemia: correlation with loss of wild-type CEBPA, consequence of epigenetic regulation. | Journal of hematology & oncology 20100101 |
| Oral Ezatiostat HCl (TLK199) and Myelodysplastic syndrome: a case report of sustained hematologic response following an abbreviated exposure. | Journal of hematology & oncology 20100101 |
| Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights. | Journal of hematology & oncology 20100101 |
| NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer. | BMC cancer 20100101 |
| High-risk myelodysplastic syndromes: chemotherapy, transplantation, and beyond. | Current hematologic malignancy reports 20100101 |
| Benzo[a]pyrene diol epoxide suppresses retinoic acid receptor-beta2 expression by recruiting DNA (cytosine-5-)-methyltransferase 3A. | Molecular cancer 20100101 |
| [Effect of 5-azadeoxycytidine and retinoic acid on expression of genomic imprinting in parthenogenetic mouse embryos]. | Ontogenez 20100101 |
| Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications. | Journal of carcinogenesis 20100101 |
| HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors. | PloS one 20100101 |
| Cyclin K and cyclin D1b are oncogenic in myeloma cells. | Molecular cancer 20100101 |
| Seladin-1 expression is regulated by promoter methylation in adrenal cancer. | BMC cancer 20100101 |
| The aberrant asynchronous replication - characterizing lymphocytes of cancer patients - is erased following stem cell transplantation. | BMC cancer 20100101 |
| Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors. | PloS one 20100101 |
| Epigenetics of induced pluripotency, the seven-headed dragon. | Stem cell research & therapy 20100101 |
| Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors. | Molecular cancer 20100101 |
| Identification of non-coding RNAs embracing microRNA-143/145 cluster. | Molecular cancer 20100101 |
| Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma. | BMC cancer 20100101 |
| Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies. | Journal of translational medicine 20100101 |
| Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines. | BMC cancer 20100101 |
| LPS-induced IL-8 activation in human intestinal epithelial cells is accompanied by specific histone H3 acetylation and methylation changes. | BMC microbiology 20100101 |
| Active loss of DNA methylation in two-cell stage goat embryos. | The International journal of developmental biology 20100101 |
| Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines. | Molecular cancer 20100101 |
| Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by methyl-CpG binding proteins and histone modifications. | BMC cancer 20100101 |
| Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer. | Molecular cancer 20100101 |
| BCG strain S4-Jena: An early BCG strain is capable to reduce the proliferation of bladder cancer cells by induction of apoptosis. | Cancer cell international 20100101 |
| Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer. | Molecular cancer 20100101 |
| Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices. | PloS one 20100101 |
| Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition. | Molecular cancer 20100101 |
| Altered intra-nuclear organisation of heterochromatin and genes in ICF syndrome. | PloS one 20100101 |
| An update on the safety and efficacy of decitabine in the treatment of myelodysplastic syndromes. | OncoTargets and therapy 20100101 |
| Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists. | BMC cancer 20100101 |
| Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene. | Molecular cancer 20100101 |
| Exon 2 methylation inhibits hepaCAM expression in transitional cell carcinoma of the bladder. | Urologia internationalis 20100101 |
| Challenges in treating older patients with acute myeloid leukemia. | Journal of oncology 20100101 |
| BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines. | Cancer immunity 20100101 |
| Oxidative stress and DNA methylation in prostate cancer. | Obstetrics and gynecology international 20100101 |
| Scope of nanotechnology in ovarian cancer therapeutics. | Journal of ovarian research 20100101 |
| Leucine-rich repeat protein PRAME: expression, potential functions and clinical implications for leukaemia. | Molecular cancer 20100101 |
| MicroRNA expression in human retinal pigment epithelial (ARPE-19) cells: increased expression of microRNA-9 by N-(4-hydroxyphenyl)retinamide. | Molecular vision 20100101 |
| Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine. | PloS one 20100101 |
| Identification of methylated genes associated with aggressive bladder cancer. | PloS one 20100101 |
| Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors. | BMC cancer 20100101 |
| Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics. | Genome medicine 20100101 |
| Thrombospondin-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylation. | BMC cancer 20100101 |
| Epigenetic approaches in the treatment of myelodysplastic syndromes: clinical utility of azacitidine. | OncoTargets and therapy 20100101 |
| The Effect of Imatinib Mesylate for Newly Diagnosed Philadelphia Chromosome-Positive, Chronic-Phase Myeloid Leukemia in Sub-Saharan African Patients: The Experience of Côte d'Ivoire. | Advances in hematology 20100101 |
| Down-regulation of the nucleotide excision repair gene XPG as a new mechanism of drug resistance in human and murine cancer cells. | Molecular cancer 20100101 |
| Short-hairpin RNA-induced suppression of adenine nucleotide translocase-2 in breast cancer cells restores their susceptibility to TRAIL-induced apoptosis by activating JNK and modulating TRAIL receptor expression. | Molecular cancer 20100101 |
| Portrait of ependymoma recurrence in children: biomarkers of tumor progression identified by dual-color microarray-based gene expression analysis. | PloS one 20100101 |
| Epigenetic regulation of CD44 in Hodgkin and non-Hodgkin lymphoma. | BMC cancer 20100101 |
| Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences. | Molecular cancer 20100101 |
| DNA methylation and cancer. | Advances in genetics 20100101 |
| Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome. | PloS one 20100101 |
| Mechanisms of transcriptional regulation and prognostic significance of activated leukocyte cell adhesion molecule in cancer. | Molecular cancer 20100101 |
| Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination. | Journal of Alzheimer's disease : JAD 20100101 |
| S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis). | Journal of translational medicine 20100101 |
| Cell line-dependent variability in HIV activation employing DNMT inhibitors. | Virology journal 20100101 |
| Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells. | Molecular cancer 20100101 |
| Safety and efficacy of azacitidine in myelodysplastic syndromes. | Drug design, development and therapy 20100101 |
| The effects of forodesine in murine and human multiple myeloma cells. | Advances in hematology 20100101 |
| The effect of differentiating and apoptotic agents on notch signalling pathway in hepatoblastoma. | Hepato-gastroenterology 20100101 |
| Evaluation of suitable reference genes for normalization of real-time reverse transcription PCR analysis in colon cancer. | Journal of experimental & clinical cancer research : CR 20100101 |
| Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma. | BMC cancer 20100101 |
| TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma. | BMC cancer 20100101 |
| Aberrant WNT/β-catenin signaling in parathyroid carcinoma. | Molecular cancer 20100101 |
| Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation. | PloS one 20100101 |
| Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells. | Molecular cancer 20100101 |
| Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation. | Molecular cancer 20100101 |
| Reactivating aberrantly hypermethylated p15 gene in leukemic T cells by a phenylhexyl isothiocyanate mediated inter-active mechanism on DNA and chromatin. | Journal of hematology & oncology 20100101 |
| Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells. | Reproductive biology and endocrinology : RB&E 20100101 |
| Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation. | PloS one 20100101 |
| S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer. | International journal of biological sciences 20100101 |
| Epigenomics in cancer management. | Cancer management and research 20100101 |
| Epstein-Barr virus-specific methylation of human genes in gastric cancer cells. | Infectious agents and cancer 20100101 |
| CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells. | PloS one 20100101 |
| Disclosing ambiguous gene aliases by automatic literature profiling. | BMC genomics 20100101 |
| Dose-modified lenalidomide induces sustained hematological response in patients with intermediate to high risk myelodysplasia. | Mediterranean journal of hematology and infectious diseases 20100101 |
| Role and timing of hematopoietic cell transplantation for myelodysplastic syndrome. | Mediterranean journal of hematology and infectious diseases 20100101 |
| New treatments for myelodysplastic syndromes. | Mediterranean journal of hematology and infectious diseases 20100101 |
| Polymorphisms in promoter sequences of MDM2, p53, and p16 genes in normal Japanese individuals. | Genetics and molecular biology 20100101 |
| Myelodysplastic syndromes/neoplasms: recent classification system based on World Health Organization Classification of Tumors - International Agency for Research on Cancer for Hematopoietic and Lymphoid Tissues. | Journal of blood medicine 20100101 |
| Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists. | Biochemical and biophysical research communications 20091225 |
| Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities. | Cancer 20091215 |
| High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors. | Cancer research 20091215 |
| Escape mechanisms from antibody therapy to lymphoma cells: downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation. | Biochemical and biophysical research communications 20091204 |
| Epigenetic modifications: new therapeutic targets in primary myelofibrosis. | Current stem cell research & therapy 20091201 |
| DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells. | Journal of cancer research and clinical oncology 20091201 |
| Involvement of DNA hypermethylation in down-regulation of the zinc transporter ZIP8 in cadmium-resistant metallothionein-null cells. | Toxicology and applied pharmacology 20091201 |
| Common fragile sites are characterized by histone hypoacetylation. | Human molecular genetics 20091201 |
| Preventing autoimmunity by regulating regulatory T-cell induction. | Journal of molecular medicine (Berlin, Germany) 20091201 |
| Induction of Foxp3 demethylation increases regulatory CD4+CD25+ T cells and prevents the occurrence of diabetes in mice. | Journal of molecular medicine (Berlin, Germany) 20091201 |
| Dual promoter regulation of death-associated protein kinase gene leads to differentially silenced transcripts by methylation in cancer. | Carcinogenesis 20091201 |
| Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20091201 |
| Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. | Molecular cancer therapeutics 20091201 |
| Mechanism of DNA replication-dependent transcriptional activation of the acetylcholinesterase gene in the Ciona intestinalis embryo. | Development, growth & differentiation 20091201 |
| A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. | Cancer prevention research (Philadelphia, Pa.) 20091201 |
| Tissue inhibitor of metalloproteinase 1 expression associated with gene demethylation confers anoikis resistance in early phases of melanocyte malignant transformation. | Translational oncology 20091201 |
| Decitabine treatment of patients with higher-risk myelodysplastic syndromes. | Leukemia research 20091201 |
| In vitro basis for treatment with hypomethylating agents and histone deacetylase inhibitors: can epigenetic changes be used to monitor treatment? | Leukemia research 20091201 |
| Epigenetic silencing of CRABP2 and MX1 in head and neck tumors. | Neoplasia (New York, N.Y.) 20091201 |
| Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance. | Neoplasia (New York, N.Y.) 20091201 |
| The human retinoblastoma gene is imprinted. | PLoS genetics 20091201 |
| Methods in DNA methylation profiling. | Epigenomics 20091201 |
| Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation. | Oncogene 20091126 |
| LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer. | Oncogene 20091126 |
| Epigenetic control of the expression of a primate-specific microRNA cluster in human cancer cells. | Epigenetics 20091116 |
| Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma (MPM) cells. | Lung cancer (Amsterdam, Netherlands) 20091101 |
| Repeated responses of an elderly patient with high-risk myelodysplastic syndrome to sequential therapy with tipifarnib, 5-azacitidine, and decitabine. | Annals of hematology 20091101 |
| Non-intensive treatment with low-dose 5-aza-2'-deoxycytidine (DAC) prior to allogeneic blood SCT of older MDS/AML patients. | Bone marrow transplantation 20091101 |
| Immunotherapy for adenoid cystic carcinoma of salivary glands: cancer/testis antigens and 5-aza-2'-deoxycytidine. | Medical hypotheses 20091101 |
| Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells. | The Prostate 20091101 |
| Identification of Sp1 and GC-boxes as transcriptional regulators of mouse Dag1 gene promoter. | American journal of physiology. Cell physiology 20091101 |
| Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms. | Molecular pharmacology 20091101 |
| 5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1. | Journal of virology 20091101 |
| Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells. | Oncology reports 20091101 |
| The 10q25.3-26.1 G protein-coupled receptor gene GPR26 is epigenetically silenced in human gliomas. | International journal of oncology 20091101 |
| Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications. | European journal of cancer (Oxford, England : 1990) 20091101 |
| DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes. | Arthritis and rheumatism 20091101 |
| [Effects and mechanisms of 5-aza-2'-deoxycytidine on endometrial cancer cell.]. | Zhonghua fu chan ke za zhi 20091101 |
| Myelodysplastic syndromes: emerging therapies, survival, and alternative outcomes. | Managed care (Langhorne, Pa.) 20091101 |
| Alternative dosing schedules for methylation inhibitors in MDS treatment. | Managed care (Langhorne, Pa.) 20091101 |
| Myelodysplastic syndromes: health care management considerations. | Managed care (Langhorne, Pa.) 20091101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20091101 |
| Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation. | Biochemical and biophysical research communications 20091016 |
| Quantitative expression and immunogenicity of MAGE-3 and -6 in upper aerodigestive tract cancer. | International journal of cancer 20091015 |
| Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines. | Cancer research 20091015 |
| Alteration of transcriptional profile in human bronchial epithelial cells induced by cigarette smoke condensate. | Toxicology letters 20091008 |
| Sodium arsenite-induced DAPK promoter hypermethylation and autophagy via ERK1/2 phosphorylation in human uroepithelial cells. | Chemico-biological interactions 20091007 |
| Epigenetic therapies move into new territory, but how exactly do they work? | Journal of the National Cancer Institute 20091007 |
| Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells. | The Journal of biological chemistry 20091002 |
| PDCD4 gene silencing in gliomas is associated with 5'CpG island methylation and unfavourable prognosis. | Journal of cellular and molecular medicine 20091001 |
| Expression of esophageal cancer related gene 4 (ECRG4), a novel tumor suppressor gene, in esophageal cancer and its inhibitory effect on the tumor growth in vitro and in vivo. | International journal of cancer 20091001 |
| Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms. | Experimental hematology 20091001 |
| Methylation-associated silencing of S100A4 expression in human epidermal cancers. | Experimental dermatology 20091001 |
| Atypical presentations of Sweet's syndrome in patients with MDS/AML receiving combinations of hypomethylating agents with histone deacetylase inhibitors. | American journal of hematology 20091001 |
| Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents. | Cancer research 20091001 |
| Development of a novel output value for quantitative assessment in methylated DNA immunoprecipitation-CpG island microarray analysis. | DNA research : an international journal for rapid publication of reports on genes and genomes 20091001 |
| Fluorescence polarization combined capillary electrophoresis immunoassay for the sensitive detection of genomic DNA methylation. | Analytical chemistry 20091001 |
| Human T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax. | Neoplasia (New York, N.Y.) 20091001 |
| Genetic factors influencing cytarabine therapy. | Pharmacogenomics 20091001 |
| [Management of anemia and bone marrow hypoplasia in the treatment of myeloid leukemia]. | Nihon rinsho. Japanese journal of clinical medicine 20091001 |
| [Novel therapeutic agents for myelodysplastic syndrome]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20091001 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20091001 |
| Enhancing survival outcomes in the management of patients with higher-risk myelodysplastic syndromes. | Cancer control : journal of the Moffitt Cancer Center 20091001 |
| Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090915 |
| Case records of the Massachusetts General Hospital. Case 28-2009. A 68-year-old man with fatigue, cough, and peripheral-blood monocytosis. | The New England journal of medicine 20090910 |
| Decitabine-induced effusions. | Leukemia research 20090901 |
| Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. | Leukemia 20090901 |
| Clinical-translational strategies for the elevation of Nm23-H1 metastasis suppressor gene expression. | Molecular and cellular biochemistry 20090901 |
| Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells. | International journal of cancer 20090901 |
| c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair. | Molecular and cellular neurosciences 20090901 |
| Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors. | The Prostate 20090901 |
| Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues. | Experimental hematology 20090901 |
| DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma. | Genes, chromosomes & cancer 20090901 |
| Decitabine combined with fractionated gemtuzumab ozogamicin therapy in patients with relapsed or refractory acute myeloid leukemia. | American journal of hematology 20090901 |
| Epigenetic silencing of death receptor 4 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in gliomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090901 |
| A 64-year-old male with fever and persistent lung infiltrate. | Respiratory care 20090901 |
| [Effect of 5-Aza-dC on FHIT gene expression in hepatocellular carcinoma cell line HepG2]. | Ai zheng = Aizheng = Chinese journal of cancer 20090901 |
| [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090901 |
| [Reversion transcriptional expression of DAPK in bladder cancer T24 cells 5-aza-2'-deoxycytidine]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901 |
| [Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2'-deoxycytidine]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090901 |
| Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling. | Journal of cellular and molecular medicine 20090901 |
| HBV life cycle: entry and morphogenesis. | Viruses 20090901 |
| Epigenetic cross-talk between DNA methylation and histone modifications in human cancers. | Yonsei medical journal 20090831 |
| Loss of human ribosomal gene CpG methylation enhances cryptic RNA polymerase II transcription and disrupts ribosomal RNA processing. | Molecular cell 20090828 |
| Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. | Toxicology letters 20090825 |
| Quantification of regional DNA methylation by liquid chromatography/tandem mass spectrometry. | Analytical biochemistry 20090815 |
| Methylation of PTCH1a gene in a subset of gastric cancers. | World journal of gastroenterology 20090814 |
| Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid. | Molecular and cellular endocrinology 20090813 |
| Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810 |
| Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer. | Oncogene 20090806 |
| Promoter CpG methylation of oestrogen receptors in leukaemia. | Bioscience reports 20090801 |
| 5-Aza-2'-deoxycytidine reactivates expression of RUNX3 by deletion of DNA methyltransferases leading to caspase independent apoptosis in colorectal cancer Lovo cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801 |
| The property of methylated APC gene promotor and its influence on lung cancer cell line. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801 |
| The presence of aberrant DNA methylation in noncancerous esophageal mucosae in association with smoking history: a target for risk diagnosis and prevention of esophageal cancers. | Cancer 20090801 |
| iTRAQ-coupled 2-D LC-MS/MS analysis of protein profile associated with HBV-modulated DNA methylation. | Proteomics 20090801 |
| RUNX3 gene methylation in epithelial ovarian cancer tissues and ovarian cancer cell lines. | Omics : a journal of integrative biology 20090801 |
| Effects of 5-Aza-CdR on the proliferation of human breast cancer cell line MCF-7 and on the expression of Apaf-1 gene. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090801 |
| Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal transcriptional regulatory region in an antifolate-resistant HeLa cell line. | Molecular cancer therapeutics 20090801 |
| Evolving strategies in the treatment of MDS and AML. | Clinical advances in hematology & oncology : H&O 20090801 |
| Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy. | Current genomics 20090801 |
| Expression and Function of Kruppel Like-Factors (KLF) in Carcinogenesis. | Current genomics 20090801 |
| Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells. | Oncogene 20090730 |
| Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2. | The Journal of biological chemistry 20090717 |
| Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. | International journal of cancer 20090715 |
| Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. | International journal of cancer 20090715 |
| Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells. | Cancer research 20090715 |
| 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090715 |
| Treatment with demethylating agent, 5-aza-2'-deoxycytidine enhances therapeutic HPV DNA vaccine potency. | Vaccine 20090709 |
| Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer. | Oncogene 20090702 |
| Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. | Breast cancer research and treatment 20090701 |
| Assessment of ATRX expression in patients with myelodysplastic syndromes treated with decitabine. | Leukemia research 20090701 |
| Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms. | Gastroenterology 20090701 |
| Successful induction therapy with decitabine in refractory childhood acute lymphoblastic leukemia. | Leukemia 20090701 |
| Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia. | European journal of cancer (Oxford, England : 1990) 20090701 |
| Role of DNA methylation in the tissue-specific expression of the CYP17A1 gene for steroidogenesis in rodents. | The Journal of endocrinology 20090701 |
| Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas. | Laboratory investigation; a journal of technical methods and pathology 20090701 |
| Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090701 |
| Aberrant methylation and reduced expression of LHX9 in malignant gliomas of childhood. | Neoplasia (New York, N.Y.) 20090701 |
| Clinical roundtable monograph. Overall survival and maintenance of MDS patients. | Clinical advances in hematology & oncology : H&O 20090701 |
| Clinical roundtable monograph. Choosing an appropriate therapy for lower-risk MDS in the community setting. | Clinical advances in hematology & oncology : H&O 20090701 |
| [Effects of 5-aza-2'-deoxycytidine on the amount of exosomes and secreted immuno-associated proteins by hepatoma cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090701 |
| Promoter methylation in the genesis of gastrointestinal cancer. | Yonsei medical journal 20090630 |
| How I treat patients with myelodysplastic syndromes. | Blood 20090618 |
| Epigenetic modifiers: basic understanding and clinical development. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090615 |
| Targeting DNA methylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090615 |
| Synergy of 5-aza-2'-deoxycytidine (DAC) and paclitaxel in both androgen-dependent and -independent prostate cancer cell lines. | Cancer letters 20090608 |
| Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia. | Evidence-based complementary and alternative medicine : eCAM 20090601 |
| Epigenetic control of differential expression of specific ERG isoforms in acute T-lymphoblastic leukemia. | Leukemia research 20090601 |
| Feasibility of allo-SCT after hypomethylating therapy with decitabine for myelodysplastic syndrome. | Bone marrow transplantation 20090601 |
| Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. | Leukemia 20090601 |
| The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. | Leukemia 20090601 |
| Erythropoietin-receptor gene regulation in neuronal cells. | Pediatric research 20090601 |
| Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer. | International journal of colorectal disease 20090601 |
| Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers. | The pharmacogenomics journal 20090601 |
| Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. | Carcinogenesis 20090601 |
| Transgelin as a suppressor is associated with poor prognosis in colorectal carcinoma patients. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20090601 |
| CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer. | International journal of oncology 20090601 |
| Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer. | Cancer research 20090601 |
| Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090601 |
| Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090601 |
| Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1. | Journal of neurochemistry 20090601 |
| Chemical decomposition of 5-aza-2'-deoxycytidine (Decitabine): kinetic analyses and identification of products by NMR, HPLC, and mass spectrometry. | Chemical research in toxicology 20090601 |
| Camptothecin-induced cell proliferation inhibition and apoptosis enhanced by DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine. | Biological & pharmaceutical bulletin 20090601 |
| DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. | Molecular cancer therapeutics 20090601 |
| Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells. | Anticancer research 20090601 |
| Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells. | Molecular cancer research : MCR 20090601 |
| Differential methylation pattern of ID4, SFRP1, and SHP1 between acute myeloid leukemia and chronic myeloid leukemia. | Journal of Korean medical science 20090601 |
| Use of epigenetic modification to induce FOXP3 expression in naïve T cells. | Transplantation proceedings 20090601 |
| Epigenetic regulation of HIV-1 latency by cytosine methylation. | PLoS pathogens 20090601 |
| [Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma]. | Ai zheng = Aizheng = Chinese journal of cancer 20090601 |
| Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation. | Biochemistry. Biokhimiia 20090601 |
| Clinical implications of gene expression profiling in myelodysplastic syndromes: recognition of ribosomal and translational gene dysregulation and development of predictive assays. | Best practice & research. Clinical haematology 20090601 |
| TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia. | Blood 20090528 |
| Treatment of chronic lymphocytic leukemia with a hypomethylating agent induces expression of NXF2, an immunogenic cancer testis antigen. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090515 |
| A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation. | Cancer research 20090515 |
| Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies: its prevalence and clinical significance. | Blood 20090514 |
| DNA methylation inhibits p53-mediated survivin repression. | Oncogene 20090514 |
| Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications. | Biochemical and biophysical research communications 20090508 |
| The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2'-deoxycytidine. | Zygote (Cambridge, England) 20090501 |
| Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma. | European journal of cancer (Oxford, England : 1990) 20090501 |
| DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin. | Mutagenesis 20090501 |
| Modulation of DNA methylation by a sesquiterpene lactone parthenolide. | The Journal of pharmacology and experimental therapeutics 20090501 |
| 5-AZA-2'-deoxycytidine (5-AZA-CdR) leads to down-regulation of Dnmt1o and gene expression in preimplantation mouse embryos. | Zygote (Cambridge, England) 20090501 |
| The comet assay: a sensitive method for detecting DNA damage in individual cells. | Methods (San Diego, Calif.) 20090501 |
| Incorporation of 5-chlorocytosine into mammalian DNA results in heritable gene silencing and altered cytosine methylation patterns. | Carcinogenesis 20090501 |
| Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells. | Cancer biology & therapy 20090501 |
| Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1. | ChemMedChem 20090501 |
| Epigenetic reversal of acquired resistance to 5-fluorouracil treatment. | Molecular cancer therapeutics 20090501 |
| Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes. | Haematologica 20090501 |
| Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20090501 |
| Epigenetic hierarchy governing Nestin expression. | Stem cells (Dayton, Ohio) 20090501 |
| Additive effects of 5-aza-2'-deoxycytidine and irradiation on clonogenic survival of human medulloblastoma cell lines. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20090501 |
| T-lymphocyte maturation-associated protein gene as a candidate metastasis suppressor for head and neck squamous cell carcinomas. | Cancer science 20090501 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090501 |
| Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine. | Blood 20090430 |
| HAI-2 is epigenetically downregulated in human hepatocellular carcinoma, and its Kunitz domain type 1 is critical for anti-invasive functions. | International journal of cancer 20090415 |
| Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival. | British journal of cancer 20090407 |
| Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules. | Cancer immunology, immunotherapy : CII 20090401 |
| Demethylating agent 5-aza-2'-deoxycytidine activates HLA-G expression in human leukemia cell lines. | Leukemia research 20090401 |
| Frequent concomitant epigenetic silencing of the stress-responsive tumor suppressor gene CADM1, and its interacting partner DAL-1 in nasal NK/T-cell lymphoma. | International journal of cancer 20090401 |
| Decitabine is an effective treatment of idiopathic myelofibrosis. | British journal of haematology 20090401 |
| The mechanism involved in the repression of the mu opioid receptor gene expression in CEM x174 cells infected by simian immunodeficiency virus. | Journal of leukocyte biology 20090401 |
| Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation. | Acta neuropathologica 20090401 |
| BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer. | Carcinogenesis 20090401 |
| The evolution of hematopoietic SCT in myelodysplastic syndrome. | Bone marrow transplantation 20090401 |
| CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers. | International journal of oncology 20090401 |
| Methylation of CLDN6, FBN2, RBP1, RBP4, TFPI2, and TMEFF2 in esophageal squamous cell carcinoma. | Oncology reports 20090401 |
| Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. | Proteomics 20090401 |
| Growth inhibition of human cancer cells by 5-aza-2'-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status. | Molecular cancer therapeutics 20090401 |
| Durable clinical and cytogenetic remission in an elderly patient with relapsed acute myeloid leukemia treated with low-dose lenalidomide. | Leukemia & lymphoma 20090401 |
| [Effect of a methylation inhibitor 5-aza-2'-deoxycytidine on SHP-1 gene expression, proliferation and apoptosis in K562 cells]. | Zhongguo shi yan xue ye xue za zhi 20090401 |
| LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors. | Epigenetics 20090401 |
| Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells. | Archives of medical research 20090401 |
| Epigenetic analysis of childhood acute lymphoblastic leukemia. | Epigenetics 20090401 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090401 |
| Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. | The Journal of biological chemistry 20090327 |
| Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. | Blood 20090319 |
| Timing is everything: order of administration of 5-aza 2' deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity. | Cancer letters 20090318 |
| 6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo. | Biochemistry 20090317 |
| Promoter hypermethylation of the ADAM23 gene in colorectal cancer cell lines and cancer tissues. | International journal of cancer 20090315 |
| Epigenetic regulation of c-ROS receptor tyrosine kinase expression in malignant gliomas. | Cancer research 20090315 |
| Extended weekly dose-dense paclitaxel/carboplatin is feasible and active in heavily pre-treated platinum-resistant recurrent ovarian cancer. | British journal of cancer 20090310 |
| Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo. | British journal of cancer 20090310 |
| Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation. | The Kobe journal of medical sciences 20090310 |
| Hydralazine inhibits human cervical cancer cell growth in vitro in association with APC demethylation and re-expression. | Cancer chemotherapy and pharmacology 20090301 |
| Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression. | Cancer immunology, immunotherapy : CII 20090301 |
| A limited number of 5-azacitidine cycles can be effective treatment in MDS. | Annals of hematology 20090301 |
| Complete cytogenetic remission after decitabine treatment in a patient with secondary AML harbouring high p15INK4b gene methylation and high global DNA methylation. | Annals of hematology 20090301 |
| Aberrant DNA methylation of the transcription factor C/EBPalpha in acute myelogenous leukemia. | Leukemia research 20090301 |
| Epigenetic regulation of E-cadherin controls endometrial receptivity. | Endocrinology 20090301 |
| Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells. | Journal of neuro-oncology 20090301 |
| Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer. | Genes, chromosomes & cancer 20090301 |
| Egr-1 negatively regulates calsequestrin expression and calcium dynamics in ventricular cells. | Cardiovascular research 20090301 |
| Differential CpG island methylation of murine adenine nucleotide translocase genes. | Biochimica et biophysica acta 20090301 |
| A systematic assessment of radiation dose enhancement by 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma. | International journal of radiation oncology, biology, physics 20090301 |
| Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090301 |
| Promising therapies in sickle cell disease. | Cardiovascular & hematological disorders drug targets 20090301 |
| GSTP1 determines cis-platinum cytotoxicity in gastric adenocarcinoma MGC803 cells: regulation by promoter methylation and extracellular regulated kinase signaling. | Anti-cancer drugs 20090301 |
| Optimal sequencing of treatments for patients with myelodysplastic syndromes. | Current opinion in hematology 20090301 |
| Changes in gene expression and assessment of DNA methylation in primary human hepatocytes and HepG2 cells exposed to the environmental contaminants-Hexabromocyclododecane and 17-beta oestradiol. | Toxicology 20090227 |
| Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine. | Life sciences 20090227 |
| The context and potential of epigenetics in oncology. | British journal of cancer 20090224 |
| ZIC1 is downregulated through promoter hypermethylation in gastric cancer. | Biochemical and biophysical research communications 20090220 |
| Silencing of the CKII alpha and CKII alpha' genes during cellular senescence is mediated by DNA methylation. | Gene 20090215 |
| The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae. | International journal of cancer 20090215 |
| Genetic and epigenetic inactivation of TNFRSF10C in human prostate cancer. | The Prostate 20090215 |
| Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target. | Cancer research 20090215 |
| Pharmacologic unmasking of epigenetically silenced genes in breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090215 |
| Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells. | Biochemical and biophysical research communications 20090213 |
| Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation. | Blood 20090212 |
| Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2'-deoxycytidine. | Cancer chemotherapy and pharmacology 20090201 |
| Progressive silencing of p14ARF in oesophageal adenocarcinoma. | Journal of cellular and molecular medicine 20090201 |
| ARHI, as a novel suppressor of cell growth and downregulated in human hepatocellular carcinoma, could contribute to hepatocarcinogenesis. | Molecular carcinogenesis 20090201 |
| Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine. | The Plant journal : for cell and molecular biology 20090201 |
| Transcriptional activity of the novel identified human yy2 promoter is modified by DNA methylation. | Gene 20090201 |
| Haemoglobin F modulation in childhood sickle cell disease. | British journal of haematology 20090201 |
| Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation. | Carcinogenesis 20090201 |
| Resistance to paclitaxel therapy is related with Bcl-2 expression through an estrogen receptor mediated pathway in breast cancer. | International journal of oncology 20090201 |
| The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. | Nature genetics 20090201 |
| Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice. | Cancer research 20090201 |
| Aberrant promoter methylation of SPARC in ovarian cancer. | Neoplasia (New York, N.Y.) 20090201 |
| Blocking the hedgehog pathway inhibits hepatoblastoma growth. | Hepatology (Baltimore, Md.) 20090201 |
| Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy. | Molecular cancer research : MCR 20090201 |
| Androgen receptor CpG island methylation status in human leukemia cancer cells. | Cancer investigation 20090201 |
| Atonal homolog 1 is a tumor suppressor gene. | PLoS biology 20090201 |
| Health-related quality of life and symptom assessment in patients with myelodysplastic syndromes. | Expert review of hematology 20090201 |
| Epigenetic inactivation of SLIT2 in human hepatocellular carcinomas. | Biochemical and biophysical research communications 20090130 |
| Promoter CpG methylation in cancer cells contributes to the regulation of MUC4. | British journal of cancer 20090127 |
| Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. | Cancer letters 20090118 |
| Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells. | Oncogene 20090115 |
| Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines. | Blood 20090115 |
| Down-regulation of Rap1GAP via promoter hypermethylation promotes melanoma cell proliferation, survival, and migration. | Cancer research 20090115 |
| Identification of aberrant promoter methylation of EDNRB gene in esophageal squamous cell carcinoma. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20090101 |
| DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. | Gut 20090101 |
| Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma. | Genes, chromosomes & cancer 20090101 |
| Epigenetic silencing of LRRC3B in colorectal cancer. | Scandinavian journal of gastroenterology 20090101 |
| Aberrant methylation of EphA7 in human prostate cancer and its relation to clinicopathologic features. | International journal of cancer 20090101 |
| Sensitization by 5-azacytidine toward death receptor-induced hepatic apoptosis. | The Journal of pharmacology and experimental therapeutics 20090101 |
| Comparative epigenomics of human and mouse mammary tumors. | Genes, chromosomes & cancer 20090101 |
| Induction of intestinalization in human esophageal keratinocytes is a multistep process. | Carcinogenesis 20090101 |
| Epigenetic therapy of leukemia: An update. | The international journal of biochemistry & cell biology 20090101 |
| 5'-azacytidine expression arrays. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells. | Cancer science 20090101 |
| Decreased expression of KAI1/CD82 metastasis suppressor gene is associated with loss of heterozygosity in melanoma cell lines. | Oncology reports 20090101 |
| Therapy-related acute myelogenous leukemia and myelodysplastic syndrome in patients with acute lymphoblastic leukemia treated with the hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimens. | Cancer 20090101 |
| Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. | Journal of immunology (Baltimore, Md. : 1950) 20090101 |
| Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells. | Cancer research 20090101 |
| High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer. | PloS one 20090101 |
| Senescence induction; a possible cancer therapy. | Molecular cancer 20090101 |
| Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation. | Molecular cancer therapeutics 20090101 |
| [5-Aza-CdR regulates the expression of RASSF1A gene in human gastric cancer cell line and inhibits the growth of cells]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090101 |
| Study of 5-Aza-CdR on transcription regulation of RASSF1A gene in the BIU87 cell line. | Urologia internationalis 20090101 |
| Relation of DNA methylation of 5'-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma. | PloS one 20090101 |
| Phenotypic instability and epigenetic variability in a diploid potato of hybrid origin, Solanum ruiz-lealii. | BMC plant biology 20090101 |
| Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells. | BMC molecular biology 20090101 |
| Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. | PloS one 20090101 |
| Differential expression of Caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion. | BMC cancer 20090101 |
| Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. | Breast cancer research : BCR 20090101 |
| Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour. | BMC medical genomics 20090101 |
| The characterization of DNA methylation-mediated regulation of bovine placental lactogen and bovine prolactin-related protein-1 genes. | BMC molecular biology 20090101 |
| ADAM33 gene silencing by promoter hypermethylation as a molecular marker in breast invasive lobular carcinoma. | BMC cancer 20090101 |
| Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays. | PloS one 20090101 |
| Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer. | PloS one 20090101 |
| MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. | PloS one 20090101 |
| Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells. | Anticancer research 20090101 |
| Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma. | BMC cancer 20090101 |
| Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism. | Nuclear receptor signaling 20090101 |
| Quantitation of DNA methylation by melt curve analysis. | BMC cancer 20090101 |
| Decytabine enhances cytotoxicity induced by oxaliplatin and 5-fluorouracil in the colorectal cancer cell line Colo-205. | Cancer cell international 20090101 |
| The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines. | World journal of surgical oncology 20090101 |
| Hypermethylation of genomic 3.3-kb repeats is frequent event in HPV-positive cervical cancer. | BMC medical genomics 20090101 |
| The 14-3-3sigma gene promoter is methylated in both human melanocytes and melanoma. | BMC cancer 20090101 |
| New clinical developments in histone deacetylase inhibitors for epigenetic therapy of cancer. | Journal of hematology & oncology 20090101 |
| Molecular prognostic markers for adult acute myeloid leukemia with normal cytogenetics. | Journal of hematology & oncology 20090101 |
| Targeted treatment of acute myeloid leukemia in older adults: role of gemtuzumab ozogamicin. | Clinical interventions in aging 20090101 |
| Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer. | BMC medical genomics 20090101 |
| Expression of BNIP3 in invasive breast cancer: correlations with the hypoxic response and clinicopathological features. | BMC cancer 20090101 |
| Development of DNA methyltransferase inhibitors for the treatment of neoplastic diseases. | Current medicinal chemistry 20090101 |
| Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer. | Breast cancer research : BCR 20090101 |
| A modified protocol for bisulfite genomic sequencing of difficult samples. | Biological procedures online 20090101 |
| Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer. | BMC cancer 20090101 |
| Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations. | Journal of translational medicine 20090101 |
| RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression. | Journal of hematology & oncology 20090101 |
| Vorinostat in solid and hematologic malignancies. | Journal of hematology & oncology 20090101 |
| 14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence. | Molecular cancer 20090101 |
| Activation of HLA-G expression by 5-aza-2 - deoxycytidine in malignant hematopoetic cells isolated from leukemia patients. | Neoplasma 20090101 |
| A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms. | PloS one 20090101 |
| Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
| Expression and mutation analysis of TIG1 (tazarotene-induced gene 1) in human gastric cancer. | Oncology research 20090101 |
| Recurrence in oral and pharyngeal cancer is associated with quantitative MGMT promoter methylation. | BMC cancer 20090101 |
| Real-time PCR analysis of genes encoding tumor antigens in esophageal tumors and a cancer vaccine. | Cancer immunity 20090101 |
| Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. | Molecular cancer 20090101 |
| NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells. | BMC cancer 20090101 |
| CHD5 is down-regulated through promoter hypermethylation in gastric cancer. | Journal of biomedical science 20090101 |
| Loss of prostasin (PRSS8) in human bladder transitional cell carcinoma cell lines is associated with epithelial-mesenchymal transition (EMT). | BMC cancer 20090101 |
| Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro. | Journal of negative results in biomedicine 20090101 |
| Fas expression in metastatic osteosarcoma cells is not regulated by CpG island methylation. | Oncology research 20090101 |
| Tackling the methylome: recent methodological advances in genome-wide methylation profiling. | Genome medicine 20090101 |
| Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells. | PloS one 20090101 |
| Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies. | Retrovirology 20090101 |
| Managing myelodysplastic symptoms in elderly patients. | Clinical interventions in aging 20090101 |
| Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC. | PloS one 20090101 |
| Promoter methylation of IGFBP-3 and p53 expression in ovarian endometrioid carcinoma. | Molecular cancer 20090101 |
| Treatment of MDS: something old, something new, something borrowed.. | Hematology. American Society of Hematology. Education Program 20090101 |
| Activin signaling in microsatellite stable colon cancers is disrupted by a combination of genetic and epigenetic mechanisms. | PloS one 20090101 |
| The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis. | Molecular cancer 20090101 |
| ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma. | BMC cancer 20090101 |
| Global demethylation of rat chondrosarcoma cells after treatment with 5-aza-2'-deoxycytidine results in increased tumorigenicity. | PloS one 20090101 |
| Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma. | Journal of experimental & clinical cancer research : CR 20090101 |
| Management of myelodysplastic syndromes in the geriatric patient. | Current hematologic malignancy reports 20090101 |
| Myelodysplastic syndrome: An update on diagnosis and therapy. | Current hematologic malignancy reports 20090101 |
| Hematopoietic stem cell transplantation in patients with myelodysplastic syndrome. | F1000 medicine reports 20090101 |
| The role of azacitidine in the management of myelodysplastic syndromes (MDS). | Cancer management and research 20090101 |
| Pathophisiology of sickle cell disease and new drugs for the treatment. | Mediterranean journal of hematology and infectious diseases 20090101 |
| Coagulopathy in Beta-thalassemia: current understanding and future perspectives. | Mediterranean journal of hematology and infectious diseases 20090101 |
| Identification and detection of a novel human endogenous retrovirus-related gene, and structural characterization of its related elements. | Genetics and molecular biology 20090101 |
| Relationship of SNCG, S100A4, S100A9 and LCN2 gene expression and DNA methylation in bladder cancer. | International journal of cancer 20081215 |
| Current management of metastatic melanoma. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081215 |
| Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer. | Biochemical and biophysical research communications 20081212 |
| Inhibition of DNA methyltransferase activity upregulates Fyn tyrosine kinase expression in Hut-78 T-lymphoma cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081201 |
| Semenogelin I expression in myeloma cells can be upregulated pharmacologically. | Leukemia research 20081201 |
| Alleviation of myelodysplastic syndrome-associated skin rush after treatment with decitabine. | European journal of haematology 20081201 |
| Predictive value of expression and promoter hypermethylation of XAF1 in hepatitis B virus-associated hepatocellular carcinoma treated with transplantation. | Annals of surgical oncology 20081201 |
| Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma. | Experimental hematology 20081201 |
| Silencing DNA methyltransferase (DNMT) enhances glioma chemosensitivity. | Oligonucleotides 20081201 |
| Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro. | Cancer biology & therapy 20081201 |
| Differentiation of human adipose-derived stem cells towards cardiomyocytes is facilitated by laminin. | Cell and tissue research 20081201 |
| The pharmacotherapy of sickle cell disease. | Expert opinion on pharmacotherapy 20081201 |
| Aberrant methylation of ADAMTS1 in non-small cell lung cancer. | Cancer genetics and cytogenetics 20081201 |
| Are new agents really making a difference in MDS? | Best practice & research. Clinical haematology 20081201 |
| NGALR is overexpressed and regulated by hypomethylation in esophageal squamous cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081201 |
| [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP]. | Ai zheng = Aizheng = Chinese journal of cancer 20081201 |
| Recent advances in low- and intermediate-1-risk myelodysplastic syndrome: developing a consensus for optimal therapy. | Clinical advances in hematology & oncology : H&O 20081201 |
| Epigenetic perturbations in the pathogenesis of mustard toxicity; hypothesis and preliminary results. | Interdisciplinary toxicology 20081201 |
| Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. | The Journal of biological chemistry 20081128 |
| PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells. | Biochemical and biophysical research communications 20081128 |
| Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS. | Gene 20081115 |
| Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors. | International journal of cancer 20081115 |
| Methylation of Tip30 promoter is associated with poor prognosis in human hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081115 |
| p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia. | Cancer research 20081115 |
| Management of myelodysplastic syndromes: 2008 update. | Oncology (Williston Park, N.Y.) 20081115 |
| Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression. | Biochemical and biophysical research communications 20081107 |
| Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells. | Carcinogenesis 20081101 |
| Frequent aberrant methylation of the promoter region of sterile alpha motif domain 14 in pulmonary adenocarcinoma. | Cancer science 20081101 |
| Demethylating agents in myeloid malignancies. | Current opinion in oncology 20081101 |
| Epigenetic changes in cancer as potential targets for prophylaxis and maintenance therapy. | Basic & clinical pharmacology & toxicology 20081101 |
| Methylation-associated silencing of SFRP1 in renal cell carcinoma. | Oncology reports 20081101 |
| The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas. | Oncology reports 20081101 |
| Involvement of epigenetic mechanisms in the regulation of secreted phospholipase A2 expressions in Jurkat leukemia cells. | Neoplasia (New York, N.Y.) 20081101 |
| AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20081101 |
| DNA hypomethylation therapies and hemoglobin disorders. [An interview with Hassana Fathallah by H&O]. | Clinical advances in hematology & oncology : H&O 20081101 |
| New agents for the treatment of AML recent study findings. | Clinical advances in hematology & oncology : H&O 20081101 |
| Future research directions for the treatment of AML. | Clinical advances in hematology & oncology : H&O 20081101 |
| Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter. | The Journal of biological chemistry 20081024 |
| Sensitivity of human prostate cancer cells to chemotherapeutic drugs depends on EndoG expression regulated by promoter methylation. | Cancer letters 20081018 |
| [Myelodysplastic syndromes: therapeutic advances and promising future]. | Medicina clinica 20081018 |
| Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases. | International journal of cancer 20081015 |
| Promoter methylation of the bone morphogenetic protein-6 gene in association with adult T-cell leukemia. | International journal of cancer 20081015 |
| The effect of thiopurine drugs on DNA methylation in relation to TPMT expression. | Biochemical pharmacology 20081015 |
| Clusterin is epigenetically regulated in prostate cancer. | International journal of cancer 20081001 |
| Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells. | Blood 20081001 |
| Promoter hypomethylation regulates CD133 expression in human gliomas. | Cell research 20081001 |
| Decitabine as 'bridge therapy' to a MUD transplant in relapsed AML postautologous stem cell transplantation. | American journal of hematology 20081001 |
| Future directions in myelodysplastic syndrome: newer agents and the role of combination approaches. | Cancer control : journal of the Moffitt Cancer Center 20081001 |
| Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. | International journal of oncology 20081001 |
| Methylation-associated silencing of TU3A in human cancers. | International journal of oncology 20081001 |
| Reprimo as a potential biomarker for early detection in gastric cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081001 |
| Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. | Cancer research 20081001 |
| [Pathogenesis of and therapeutic progress for myelodysplastic syndromes]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001 |
| The costs of drugs used to treat myelodysplastic syndromes following National Comprehensive Cancer Network Guidelines. | Journal of the National Comprehensive Cancer Network : JNCCN 20081001 |
| [Advance of study on demethylation in leukemia - review]. | Zhongguo shi yan xue ye xue za zhi 20081001 |
| Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor. | Neurosurgery 20081001 |
| Expression and promoter methylation status of mismatch repair gene hMLH1 and hMSH2 in epithelial ovarian cancer. | The Australian & New Zealand journal of obstetrics & gynaecology 20081001 |
| [Histone H3 lysine 9 methylation is associated with the expression of hMLH1 and DNA methylation in gastric cancer cells]. | Zhonghua yi xue za zhi 20080916 |
| Epigenetic silencing of cell adhesion molecule 1 in different cancer progenitor cells of transgenic c-Myc and c-Raf mouse lung tumors. | Cancer research 20080915 |
| Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential? | British journal of cancer 20080902 |
| Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. | Breast cancer research and treatment 20080901 |
| Epigenetic inactivation of secreted Frizzled-related proteins in acute myeloid leukaemia. | British journal of haematology 20080901 |
| EXTL3 promoter methylation down-regulates EXTL3 and heparan sulphate expression in mucinous colorectal cancers. | The Journal of pathology 20080901 |
| Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. | The Journal of clinical endocrinology and metabolism 20080901 |
| Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells. | International journal of cancer 20080901 |
| Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. | Theriogenology 20080901 |
| DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication. | Blood 20080901 |
| Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis. | Molecular and cellular biology 20080901 |
| Potential link between estrogen receptor-alpha gene hypomethylation and uterine fibroid formation. | Molecular human reproduction 20080901 |
| LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer. | Cancer research 20080901 |
| Azacytidine causes complex DNA methylation responses in myeloid leukemia. | Molecular cancer therapeutics 20080901 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20080901 |
| Cancer prevention: epigenetics steps up to the plate. | Cancer prevention research (Philadelphia, Pa.) 20080901 |
| Cause and consequences of genetic and epigenetic alterations in human cancer. | Current genomics 20080901 |
| [5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells]. | Zhonghua yi xue za zhi 20080819 |
| Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues. | Biochemical and biophysical research communications 20080815 |
| 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1. | Cancer letters 20080808 |
| Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice. | Cancer chemotherapy and pharmacology 20080801 |
| ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. | Journal of cancer research and clinical oncology 20080801 |
| Current status of epigenetic treatment in myelodysplastic syndromes. | Annals of hematology 20080801 |
| DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines. | International journal of cancer 20080801 |
| Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. | International journal of cancer 20080801 |
| Epigenetic remodeling during arsenical-induced malignant transformation. | Carcinogenesis 20080801 |
| Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080801 |
| Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential. | Diabetologia 20080801 |
| Hypermethylation of CXCR4 promoter in CD34+ cells from patients with primary myelofibrosis. | Stem cells (Dayton, Ohio) 20080801 |
| Gene expression and methylation status of 14-3-3sigma in human renal carcinoma tissues. | IUBMB life 20080801 |
| Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells. | International immunology 20080801 |
| 5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis. | Cancer investigation 20080801 |
| Modest reactivation of the mutant FMR1 gene by valproic acid is accompanied by histone modifications but not DNA demethylation. | Pharmacogenetics and genomics 20080801 |
| CpG methylation in exon 1 of transcription factor 4 increases with age in normal gastric mucosa and is associated with gene silencing in intestinal-type gastric cancers. | Carcinogenesis 20080801 |
| Downmodulation of dimethyl transferase activity enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in prostate cancer cells. | International journal of oncology 20080801 |
| Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma. | Oncology reports 20080801 |
| Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. | Hepatology (Baltimore, Md.) 20080801 |
| New drugs in acute myeloid leukemia. | Seminars in oncology 20080801 |
| Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. | PLoS genetics 20080801 |
| [Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. | Zhongguo shi yan xue ye xue za zhi 20080801 |
| Retinoic acid receptor beta2 re-expression and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment. | Journal of endocrinological investigation 20080801 |
| [Hypomethylation of 5'CpG island of insulin-like growth factor binding protein-related protein 1 is associated with its overexpression in colorectal cancer]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20080801 |
| Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type beta-catenin nuclear accumulation in lung tumorigenesis. | Oncogene 20080724 |
| Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation. | International journal of cancer 20080715 |
| Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis. | International journal of cancer 20080715 |
| A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts. | Cell cycle (Georgetown, Tex.) 20080715 |
| Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells. | Oncogene 20080703 |
| CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas. | Journal of the National Cancer Institute 20080702 |
| Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer. | Carcinogenesis 20080701 |
| Cytogenetic features in myelodysplastic syndromes. | Annals of hematology 20080701 |
| Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine. | International journal of cancer 20080701 |
| Frequent silencing of a putative tumor suppressor gene melatonin receptor 1 A (MTNR1A) in oral squamous-cell carcinoma. | Cancer science 20080701 |
| DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer. | Gastroenterology 20080701 |
| CpG hypermethylation of the UCHL1 gene promoter is associated with pathogenesis and poor prognosis in renal cell carcinoma. | The Journal of urology 20080701 |
| Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. | Oncology reports 20080701 |
| Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines. | Cancer investigation 20080701 |
| Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines. | Science in China. Series C, Life sciences 20080701 |
| Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. | The Journal of biological chemistry 20080620 |
| Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. | Cancer research 20080615 |
| ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080615 |
| Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080615 |
| Induction of MHC class I-related chain B (MICB) by 5-aza-2'-deoxycytidine. | Biochemical and biophysical research communications 20080613 |
| Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma. | Oncogene 20080605 |
| p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. | Oncogene 20080605 |
| SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response. | British journal of cancer 20080603 |
| Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. | Leukemia research 20080601 |
| The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma. | International journal of cancer 20080601 |
| DCC promoter hypermethylation in esophageal squamous cell carcinoma. | International journal of cancer 20080601 |
| Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies. | Cancer 20080601 |
| Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells. | The Journal of allergy and clinical immunology 20080601 |
| Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. | Placenta 20080601 |
| DNA methylation controls Foxp3 gene expression. | European journal of immunology 20080601 |
| Generalized granuloma annulare as an initial manifestation of chronic myelomonocytic leukemia: a report of 2 cases. | The American Journal of dermatopathology 20080601 |
| Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells. | International journal of oncology 20080601 |
| Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. | Cancer research 20080601 |
| Identification of 6-benzylthioinosine as a myeloid leukemia differentiation-inducing compound. | Cancer research 20080601 |
| Intertumor and intratumor NY-ESO-1 expression heterogeneity is associated with promoter-specific and global DNA methylation status in ovarian cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080601 |
| The human receptor tyrosine kinase Axl gene--promoter characterization and regulation of constitutive expression by Sp1, Sp3 and CpG methylation. | Bioscience reports 20080601 |
| Epigenetic treatment of myelodysplastic syndromes and acute myeloid leukemias. | Current medicinal chemistry 20080601 |
| Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of bladder transitional cell carcinoma to Cisplatin. | Urology 20080601 |
| DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. | Cancer cell 20080601 |
| Visualization and measurement of DNA methyltransferase activity in living cells. | Current protocols in cell biology 20080601 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20080601 |
| Investigation of transcriptional gene silencing and mechanism induced by shRNAs targeted to RUNX3 in vitro. | World journal of gastroenterology 20080521 |
| Effects of cellular differentiation, chromosomal integration and 5-aza-2'-deoxycytidine treatment on human papillomavirus-16 DNA methylation in cultured cell lines. | Virology 20080510 |
| An epigenetic disorder may cause aberrant expression of aromatase gene in endometriotic stromal cells. | Fertility and sterility 20080501 |
| DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity. | Neurobiology of learning and memory 20080501 |
| Resistance to Imatinib Mesylate-induced apoptosis in acute lymphoblastic leukemia is associated with PTEN down-regulation due to promoter hypermethylation. | Leukemia research 20080501 |
| Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer. | Oncogene 20080501 |
| DNA hypomethylation circuit of the mouse oocyte-specific histone H1foo gene in female germ cell lineage. | Biology of reproduction 20080501 |
| Frequent hypermethylation of DBC1 in malignant lymphoproliferative neoplasms. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20080501 |
| Epigenetic and HIF-1 regulation of stanniocalcin-2 expression in human cancer cells. | Experimental cell research 20080501 |
| Reduced T-cadherin expression and promoter methylation are associated with the development and progression of hepatocellular carcinoma. | International journal of oncology 20080501 |
| Promoter methylation of death-associated protein kinase and its role in irradiation response in cervical cancer. | Oncology reports 20080501 |
| ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. | Autoimmunity 20080501 |
| Quantitative promoter hypermethylation analysis of cancer-related genes in salivary gland carcinomas: comparison with methylation-specific PCR technique and clinical significance. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080501 |
| Monitoring the effect of belinostat in solid tumors by H4 acetylation. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20080501 |
| Genomic structure, alternative splicing and expression of TG-interacting factor, in human myeloid leukemia blasts and cell lines. | Biochimica et biophysica acta 20080501 |
| Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells. | Neoplasia (New York, N.Y.) 20080501 |
| Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia. | Current cancer drug targets 20080501 |
| Tetraploidy and 5q deletion in myelodysplastic syndrome: a case report. | Cancer genetics and cytogenetics 20080501 |
| Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor. | Molecular cancer therapeutics 20080501 |
| Interferon regulatory factors IRF5 and IRF7 inhibit growth and induce senescence in immortal Li-Fraumeni fibroblasts. | Molecular cancer research : MCR 20080501 |
| TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells. | Molecular cancer research : MCR 20080501 |
| Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis. | PLoS medicine 20080501 |
| Epigenetic disregulation induces cell growth retardation in primary cultured glial cells. | Journal of bioscience and bioengineering 20080501 |
| [Promoter methylation status of PTEN gene and the effect of induced demethylation in leukemia cell lines]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20080501 |
| Homocysteine inhibits arterial endothelial cell growth through transcriptional downregulation of fibroblast growth factor-2 involving G protein and DNA methylation. | Circulation research 20080425 |
| Polyaminohydroxamic acids and polyaminobenzamides as isoform selective histone deacetylase inhibitors. | Journal of medicinal chemistry 20080424 |
| Genetic and epigenetic mechanisms combine to control MMP1 expression and its association with preterm premature rupture of membranes. | Human molecular genetics 20080415 |
| MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells. | Cancer research 20080415 |
| Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. | Cancer research 20080415 |
| MS-275 synergistically enhances the growth inhibitory effects of RAMBA VN/66-1 in hormone-insensitive PC-3 prostate cancer cells and tumours. | British journal of cancer 20080408 |
| Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol. | Environment international 20080401 |
| Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). | Cancer chemotherapy and pharmacology 20080401 |
| Efficacy of decitabine in the treatment of patients with chronic myelomonocytic leukemia (CMML). | Leukemia research 20080401 |
| Frequent epigenetic inactivation of hSRBC in gastric cancer and its implication in attenuated p53 response to stresses. | International journal of cancer 20080401 |
| Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. | Stem cells (Dayton, Ohio) 20080401 |
| 5-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene. | British journal of pharmacology 20080401 |
| Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation. | Cancer 20080401 |
| Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. | Experimental eye research 20080401 |
| Clinical effectiveness of decitabine in severe sickle cell disease. | British journal of haematology 20080401 |
| Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo. | Journal of cell science 20080401 |
| Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. | Cancer research 20080401 |
| Methylation silencing of transforming growth factor-beta receptor type II in rat prostate cancers. | Cancer research 20080401 |
| DNA methyltransferase inhibitors: class effect or unique agents? | Leukemia & lymphoma 20080401 |
| Activity of decitabine in patients with myelodysplastic syndrome previously treated with azacitidine. | Leukemia & lymphoma 20080401 |
| Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells. | Stem cells and development 20080401 |
| [Analysis of in vitro anti-leukemia effect of 5-aza-2'-deoxycitydine]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080401 |
| The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage. | BMB reports 20080331 |
| The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth. | Oncogene 20080327 |
| Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. | British journal of cancer 20080325 |
| 5-Aza-2'-deoxycytidine increases the expression of anti-angiogenic vascular endothelial growth factor 189b variant in human lung microvascular endothelial cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080301 |
| IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells. | International journal of cancer 20080301 |
| DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. | Human molecular genetics 20080301 |
| Supportive care, growth factors, and new therapies in myelodysplastic syndromes. | Blood reviews 20080301 |
| The transglutaminase 2 gene (TGM2), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer. | Carcinogenesis 20080301 |
| The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle. | Journal of hepatology 20080301 |
| Iron overload in myelodysplastic syndromes (MDS) - diagnosis, management, and response criteria: a proposal of the Austrian MDS platform. | European journal of clinical investigation 20080301 |
| Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion. | Carcinogenesis 20080301 |
| Hedgehog signalling in medulloblastoma, glioblastoma and neuroblastoma. | Oncology reports 20080301 |
| Cutting edge: TGF-beta-induced expression of Foxp3 in T cells is mediated through inactivation of ERK. | Journal of immunology (Baltimore, Md. : 1950) 20080301 |
| Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. | Neoplasia (New York, N.Y.) 20080301 |
| Differential expression of secretory phospholipases A2 in normal and malignant prostate cell lines: regulation by cytokines, cell signaling pathways, and epigenetic mechanisms. | Neoplasia (New York, N.Y.) 20080301 |
| [Myelodysplastic syndrome]. | Nihon rinsho. Japanese journal of clinical medicine 20080301 |
| SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. | PLoS genetics 20080301 |
| Expression of BORIS in melanoma: lack of association with MAGE-A1 activation. | International journal of cancer 20080215 |
| The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1. | Human molecular genetics 20080215 |
| Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells. | Biochemical pharmacology 20080215 |
| Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. | Blood 20080215 |
| Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215 |
| Sequential changes in genome-wide DNA methylation status during adipocyte differentiation. | Biochemical and biophysical research communications 20080208 |
| Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells. | FEBS letters 20080206 |
| An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment. | The Journal of biological chemistry 20080201 |
| Reduced expression of DNA topoisomerase I in SF295 human glioblastoma cells selected for resistance to homocamptothecin and diflomotecan. | Molecular pharmacology 20080201 |
| Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. | DNA repair 20080201 |
| DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines. | The Prostate 20080201 |
| Drugs affecting prelamin A processing: effects on heterochromatin organization. | Experimental cell research 20080201 |
| Induction of ID1 expression and apoptosis by the histone deacetylase inhibitor (trichostatin A) in human acute myeloid leukaemic cells. | Cell proliferation 20080201 |
| [Effect of (-)-epigallocatechin-3-gallate and 5-AZA-CdR on expression of X-linked inhibitor of apoptosis protein-associated factor 1 in human leukemia HL-60 and K562 cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080201 |
| Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion. | Molecular cancer research : MCR 20080201 |
| DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells. | Molecular cancer research : MCR 20080201 |
| [Methylation of PTPRG gene and its regulation in gastric cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080201 |
| Therapeutic options for chronic myeloid leukemia: focus on imatinib (Glivec, Gleevectrade mark). | Therapeutics and clinical risk management 20080201 |
| A review of topotecan in combination chemotherapy for advanced cervical cancer. | Therapeutics and clinical risk management 20080201 |
| The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation. | Oncogene 20080131 |
| Regulation of demethylation and re-expression of RASSF1A gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB. | World journal of gastroenterology 20080128 |
| Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL. | Oncogene 20080117 |
| Methylation of TIMP3 in esophageal squamous cell carcinoma. | World journal of gastroenterology 20080114 |
| Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes. | Oncogene 20080110 |
| Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma. | Brain research 20080110 |
| PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells. | Leukemia research 20080101 |
| Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer. | The Journal of pathology 20080101 |
| Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney. | American journal of physiology. Renal physiology 20080101 |
| Expression of the human Sd(a) beta-1,4-N-acetylgalactosaminyltransferase II gene is dependent on the promoter methylation status. | Glycobiology 20080101 |
| Dipeptidyl peptidase IV (DPPIV), a candidate tumor suppressor gene in melanomas is silenced by promoter methylation. | Frontiers in bioscience : a journal and virtual library 20080101 |
| DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. | Molecular and cellular biology 20080101 |
| Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis. | Cancer 20080101 |
| CpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 binding. | Nucleic acids research 20080101 |
| Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription. | Nature cell biology 20080101 |
| Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells. | Cancer research 20080101 |
| Myelodysplastic syndromes: introduction. | Seminars in hematology 20080101 |
| DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes. | Seminars in hematology 20080101 |
| Targeted therapies in myelodysplastic syndrome. | Seminars in hematology 20080101 |
| Regulation of the p14ARF promoter by DNA methylation. | Cell cycle (Georgetown, Tex.) 20080101 |
| Hypermethylation of the AKAP12 promoter is a biomarker of Barrett's-associated esophageal neoplastic progression. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080101 |
| DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. | Molecular cancer 20080101 |
| Pharmacogenomics and therapeutics of hemoglobinopathies. | Hemoglobin 20080101 |
| Hypermethylated MAL gene - a silent marker of early colon tumorigenesis. | Journal of translational medicine 20080101 |
| Involvement of CCAAT/enhancer binding protein-beta (C/EBPbeta) in epigenetic regulation of mouse methionine adenosyltransferase 1A gene expression. | The international journal of biochemistry & cell biology 20080101 |
| Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-aza-2'-deoxycytidine. | The international journal of biochemistry & cell biology 20080101 |
| Methylation alterations are not a major cause of PTTG1 misregulation. | BMC cancer 20080101 |
| Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling. | PloS one 20080101 |
| Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier. | BMC cancer 20080101 |
| Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer. | BMC cancer 20080101 |
| Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors. | Molecular cancer 20080101 |
| SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro. | BMC cancer 20080101 |
| Generation of a genomic tiling array of the human major histocompatibility complex (MHC) and its application for DNA methylation analysis. | BMC medical genomics 20080101 |
| Anticancer drug discovery targeting DNA hypermethylation. | Current medicinal chemistry 20080101 |
| Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma. | Pathobiology : journal of immunopathology, molecular and cellular biology 20080101 |
| CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23. | BMC cancer 20080101 |
| HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells. | PloS one 20080101 |
| miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. | BMC medicine 20080101 |
| Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. | Journal of hematology & oncology 20080101 |
| Role of retinoic receptors in lung carcinogenesis. | Journal of experimental & clinical cancer research : CR 20080101 |
| Differential interactions of the autonomous pathway RRM proteins and chromatin regulators in the silencing of Arabidopsis targets. | PloS one 20080101 |
| Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy. | BMC gastroenterology 20080101 |
| In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma. | PloS one 20080101 |
| Aberrant promoter CpG islands methylation of tumor suppressor genes in cholangiocarcinoma. | Oncology research 20080101 |
| Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: comparison of rat and mouse. | BMC genomics 20080101 |
| Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours. | Breast cancer research : BCR 20080101 |
| DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage. | BMC medical genomics 20080101 |
| Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma. | Molecular cancer 20080101 |
| DNA methylation: its role in cancer development and therapy. | Current problems in cancer 20080101 |
| Epigenetic modifications in rheumatoid arthritis. | Arthritis research & therapy 20080101 |
| Promoter hypermethylation-mediated inactivation of LRRC4 in gliomas. | BMC molecular biology 20080101 |
| Synergistic effect of 5-Aza-2'-deoxycytidine and genistein in combination against leukemia. | Oncology research 20080101 |
| Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer. | Molecular cancer 20080101 |
| Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression. | BMC cancer 20080101 |
| Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene. | Epigenetics & chromatin 20080101 |
| Preclinical evaluation of the antineoplastic action of 5-aza-2'-deoxycytidine and different histone deacetylase inhibitors on human Ewing's sarcoma cells. | Cancer cell international 20080101 |
| Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype. | Journal of ovarian research 20080101 |
| Aberrant promoter methylation of the TPEF gene in esophageal squamous cell carcinoma. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20080101 |
| Multivariate gene expression analysis reveals functional connectivity changes between normal/tumoral prostates. | BMC systems biology 20080101 |
| Recent patents concerning diagnostic and therapeutic applications of aberrantly methylated sequences in pancreatic cancer. | Recent patents on DNA & gene sequences 20080101 |
| Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients. | BMC cancer 20080101 |
| Antiangiogenic therapy in myelodysplastic syndromes: is there a role? | Current hematologic malignancy reports 20080101 |
| Downregulation of regenerating islet-derived 3 alpha (REG3A) in primary human gastric adenocarcinomas. | Experimental & molecular medicine 20071231 |
| [Epigenetic regulation of expression of retinoic acid receptor beta gene in leukemia cell]. | Zhonghua yi xue za zhi 20071225 |
| Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis. | Cancer research 20071215 |
| Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines. | World journal of gastroenterology 20071214 |
| PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation. | Oncogene 20071213 |
| Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention. | Annals of the rheumatic diseases 20071201 |
| Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma. | Leukemia 20071201 |
| Downregulation of microRNAs-143 and -145 in B-cell malignancies. | Cancer science 20071201 |
| Downregulation of several fibulin genes in prostate cancer. | The Prostate 20071201 |
| Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor. | The Prostate 20071201 |
| Alterations in the expression of PDCD4 in ductal carcinoma of the breast. | Oncology reports 20071201 |
| Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that differ in susceptibility to histone deacetylase inhibitors. | International journal of oncology 20071201 |
| Identification of methylation-silenced genes in colorectal cancer cell lines: genomic screening using oligonucleotide arrays. | Scandinavian journal of gastroenterology 20071201 |
| WNT5A, a putative tumour suppressor of lymphoid malignancies, is inactivated by aberrant methylation in acute lymphoblastic leukaemia. | European journal of cancer (Oxford, England : 1990) 20071201 |
| Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer. | Gastroenterology 20071201 |
| Epigenetic lesions in malignant melanoma. | Current pharmaceutical biotechnology 20071201 |
| Targeted therapies in the management of metastatic bladder cancer. | Biologics : targets & therapy 20071201 |
| Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer. | World journal of gastroenterology 20071121 |
| Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours. | British journal of cancer 20071119 |
| Quantitative hypermethylation of NMDAR2B in human gastric cancer. | International journal of cancer 20071101 |
| Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubis. | American journal of hematology 20071101 |
| p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma. | Journal of clinical pathology 20071101 |
| Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC). | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20071101 |
| Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071101 |
| The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer. | The American journal of pathology 20071101 |
| Regulation of the CLDN3 gene in ovarian cancer cells. | Cancer biology & therapy 20071101 |
| Methylation-induced silencing of ASC/TMS1, a pro-apoptotic gene, is a late-stage event in colorectal cancer. | Cancer biology & therapy 20071101 |
| Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island. | Cancer cell 20071101 |
| Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells. | Molecular cancer therapeutics 20071101 |
| Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. | Neoplasia (New York, N.Y.) 20071101 |
| Treatment options in advanced myelodysplastic syndrome, with emphasis on epigenetic therapy. | International journal of hematology 20071101 |
| Evaluating new treatment options for MDS. | Clinical advances in hematology & oncology : H&O 20071101 |
| [Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20071101 |
| ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations. | FEBS letters 20071030 |
| Combining epigenetic and cytotoxic therapy in the treatment of solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010 |
| Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010 |
| Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer. | British journal of cancer 20071008 |
| Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells. | Oncogene 20071004 |
| Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer. | Oncogene 20071004 |
| Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation. | Oral oncology 20071001 |
| Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis. | Leukemia research 20071001 |
| Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells. | Journal of cellular physiology 20071001 |
| Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. | Journal of molecular medicine (Berlin, Germany) 20071001 |
| Promoter methylation regulates estrogen receptor 2 in human endometrium and endometriosis. | Biology of reproduction 20071001 |
| Transcriptional silencing of hedgehog-interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer. | The Journal of pathology 20071001 |
| Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements. | The FEBS journal 20071001 |
| CMTM5 exhibits tumor suppressor activities and is frequently silenced by methylation in carcinoma cell lines. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071001 |
| Evaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor types. | Cancer biology & therapy 20071001 |
| Tumor suppressor gene inactivation during cadmium-induced malignant transformation of human prostate cells correlates with overexpression of de novo DNA methyltransferase. | Environmental health perspectives 20071001 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20071001 |
| Effects of 5-Aza-CdR on cell proliferation of breast cancer cell line MDA-MB-435S and expression of maspin gene. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20071001 |
| Decitabine in the treatment of myelodysplastic syndromes. | Therapeutics and clinical risk management 20071001 |
| Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma. | Oncogene 20070927 |
| Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma. | Oncogene 20070920 |
| Gene induction and apoptosis in human hepatocellular carci-noma cells SMMC-7721 exposed to 5-aza-2'-deoxycytidine. | Chinese medical journal 20070920 |
| RNA interference-mediated knockdown of DNMT1 and DNMT3B induces CXCL12 expression in MCF-7 breast cancer and AsPC1 pancreatic carcinoma cell lines. | Cancer letters 20070918 |
| Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer. | International journal of cancer 20070915 |
| Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma. | The Prostate 20070915 |
| MicroRNA signatures in human ovarian cancer. | Cancer research 20070915 |
| Clonogenic acute myelogenous leukemia cells are heterogeneous with regard to regulation of differentiation and effect of epigenetic pharmacological targeting. | Leukemia research 20070901 |
| Adverse effects of 5-aza-2'-deoxycytidine on spermatogenesis include reduced sperm function and selective inhibition of de novo DNA methylation. | The Journal of pharmacology and experimental therapeutics 20070901 |
| Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes. | Developmental dynamics : an official publication of the American Association of Anatomists 20070901 |
| Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901 |
| Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition. | British journal of haematology 20070901 |
| Down-regulation of placenta growth factor by promoter hypermethylation in human lung and colon carcinoma. | Molecular cancer research : MCR 20070901 |
| Decitabine up-regulates S100A2 expression and synergizes with IFN-gamma to kill uveal melanoma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070901 |
| The use of hypomethylating agents in the treatment of hematologic malignancies. | Leukemia & lymphoma 20070901 |
| Myelodysplastic syndromes: review of pathophysiology and current novel treatment approaches. | Current cancer drug targets 20070901 |
| Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation. | AAPS PharmSciTech 20070901 |
| Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis. | Oncogene 20070830 |
| SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas. | Oncogene 20070816 |
| Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer. | Cancer research 20070815 |
| Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors. | Oncogene 20070809 |
| Ornithine decarboxylase antizyme upregulates DNA-dependent protein kinase and enhances the nonhomologous end-joining repair of DNA double-strand breaks in human oral cancer cells. | Biochemistry 20070807 |
| An MLL-SEPT9 fusion and t(11;17)(q23;q25) associated with de novo myelodysplastic syndrome. | Leukemia research 20070801 |
| Frequent inactivation of SPARC by promoter hypermethylation in colon cancers. | International journal of cancer 20070801 |
| Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer. | International journal of cancer 20070801 |
| Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. | International journal of cancer 20070801 |
| Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070801 |
| Transcriptional activation of steroidogenic factor-1 by hypomethylation of the 5' CpG island in endometriosis. | The Journal of clinical endocrinology and metabolism 20070801 |
| Epigenetic inheritance in rice plants. | Annals of botany 20070801 |
| Preferential cytogenetic response to continuous intravenous low-dose decitabine (DAC) administration in myelodysplastic syndrome with monosomy 7. | Blood 20070801 |
| Decitabine dosage in myelodysplastic syndromes. | Blood 20070801 |
| DNA methylation regulates MicroRNA expression. | Cancer biology & therapy 20070801 |
| Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070801 |
| The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma. | Cancer genetics and cytogenetics 20070801 |
| Decitabine and its role in the treatment of hematopoietic malignancies. | Leukemia & lymphoma 20070801 |
| Monocytic skin nodules in chronic myelomonocytic leukemia: clinical response to decitabine therapy. | Leukemia & lymphoma 20070801 |
| High expressions of neuronatin isoforms in favorable neuroblastoma. | Journal of pediatric hematology/oncology 20070801 |
| Lenalidomide: a brief review of its therapeutic potential in myelodysplastic syndromes. | Therapeutics and clinical risk management 20070801 |
| Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells. | Biochemical and biophysical research communications 20070727 |
| Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance. | Oncogene 20070726 |
| Hypermethylation and transcriptional downregulation of the CITED4 gene at 1p34.2 in oligodendroglial tumours with allelic losses on 1p and 19q. | Oncogene 20070726 |
| [The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. | Zhonghua yi xue za zhi 20070724 |
| Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers. | Oncogene 20070719 |
| Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma. | British journal of cancer 20070716 |
| Silencing of tissue factor pathway inhibitor-2 gene in malignant melanomas. | International journal of cancer 20070715 |
| Effect of cytarabine and decitabine in combination in human leukemic cell lines. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070715 |
| Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. | Oncogene 20070712 |
| Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter. | Oncogene 20070705 |
| Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. | Breast cancer research and treatment 20070701 |
| Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701 |
| The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. | Laboratory investigation; a journal of technical methods and pathology 20070701 |
| Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors. | Genes, chromosomes & cancer 20070701 |
| Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. | Molecular and cellular biology 20070701 |
| Silencing of Lactotransferrin expression by methylation in prostate cancer progression. | Cancer biology & therapy 20070701 |
| Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. | Cancer research 20070701 |
| Effects of chromatin-modifying agents on CD34+ cells from patients with idiopathic myelofibrosis. | Cancer research 20070701 |
| DNA damage, homology-directed repair, and DNA methylation. | PLoS genetics 20070701 |
| Use of hypomethylating agents in myelodysplastic syndromes. | Clinical advances in hematology & oncology : H&O 20070701 |
| Effects of 5-aza-2'-deoxycytidine on the gene expression profile during embryogenesis of the Ascidian ciona intestinalis: a microarray analysis. | Zoological science 20070701 |
| [Relationship between RAR-beta gene expression defect and its methylation]. | Zhonghua fu chan ke za zhi 20070701 |
| Downregulation and CpG island hypermethylation of NES1/hK10 gene in the pathogenesis of human gastric cancer. | Cancer letters 20070618 |
| Aberrant hypermethylation of the FGFR2 gene in human gastric cancer cell lines. | Biochemical and biophysical research communications 20070615 |
| Epigenetic and functional analysis of IGFBP3 and IGFBPrP1 in cellular immortalization. | Biochemical and biophysical research communications 20070608 |
| A selective activity of DNMTi decitabine on AML1ETO positive cells? | Leukemia research 20070601 |
| Inactivation of LLC1 gene in nonsmall cell lung cancer. | International journal of cancer 20070601 |
| DNA methylation regulates tissue-specific expression of Shank3. | Journal of neurochemistry 20070601 |
| Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells. | Biochemical and biophysical research communications 20070601 |
| Overlapping roles of the methylated DNA-binding protein MBD1 and polycomb group proteins in transcriptional repression of HOXA genes and heterochromatin foci formation. | The Journal of biological chemistry 20070601 |
| Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells. | The Journal of pathology 20070601 |
| Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2'-deoxycytidine in cutaneous melanoma: immunotherapeutic implications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070601 |
| Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth. | Cancer research 20070601 |
| Down-regulation of the progesterone receptor by the methylation of progesterone receptor gene in endometrial cancer cells. | Cancer genetics and cytogenetics 20070601 |
| Optimization of comparative expressed sequence hybridization for genome-wide expression profiling at chromosome level. | Cancer genetics and cytogenetics 20070601 |
| [Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines]. | Ai zheng = Aizheng = Chinese journal of cancer 20070601 |
| Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20070601 |
| DNA methyltransferases as targets for cancer therapy. | Drugs of today (Barcelona, Spain : 1998) 20070601 |
| Re-expression of RASSF1A by 5-Aza-CdR induced demethylation of the promoter region in human biliary tract carcinoma cells. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070601 |
| Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors. | Cancer letters 20070518 |
| Genetic redundancy in human cervical carcinoma cells: identification of cells with 'normal' properties. | International journal of cancer 20070515 |
| MAGE-A9 mRNA and protein expression in bladder cancer. | International journal of cancer 20070515 |
| Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma. | Cancer 20070515 |
| Tumor suppressor activity of CCAAT/enhancer binding protein alpha is epigenetically down-regulated in head and neck squamous cell carcinoma. | Cancer research 20070515 |
| Frequent epigenetic inactivation of cystatin M in breast carcinoma. | Oncogene 20070510 |
| Acute myeloid leukemia and myelodysplastic syndromes in older patients. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070510 |
| Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites. | Cancer letters 20070508 |
| Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes. | Proceedings of the National Academy of Sciences of the United States of America 20070508 |
| Environment factors can influence mitochondrial inheritance in the fungus Cryptococcus neoformans. | Fungal genetics and biology : FG & B 20070501 |
| Up-regulation of DLK1 as an imprinted gene could contribute to human hepatocellular carcinoma. | Carcinogenesis 20070501 |
| Decreased expression of insulin-like growth factor binding protein 7 in human colorectal carcinoma is related to DNA methylation. | Journal of cancer research and clinical oncology 20070501 |
| Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15. | Annals of surgical oncology 20070501 |
| The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia. | Blood 20070501 |
| Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines. | Biochemical pharmacology 20070501 |
| The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo. | FEMS microbiology letters 20070501 |
| Discovery of epigenetically silenced genes in acute myeloid leukemias. | Leukemia 20070501 |
| Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression. | The Journal of pathology 20070501 |
| Aberrant DNA methylation of the Src kinase Hck, but not of Lyn, in Philadelphia chromosome negative acute lymphocytic leukemia. | Leukemia 20070501 |
| The incidence and impact of thrombocytopenia in myelodysplastic syndromes. | Cancer 20070501 |
| Down-regulation of IL-7Ralpha expression in human T cells via DNA methylation. | Journal of immunology (Baltimore, Md. : 1950) 20070501 |
| Methylation of Ras association domain family protein 1, isoform A correlated with proliferation and drug resistance in hepatocellular carcinoma cell line SMMC-7721. | Journal of gastroenterology and hepatology 20070501 |
| LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer. | Cancer research 20070501 |
| Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20070501 |
| Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel. | Urology 20070501 |
| Identification of epigenetically silenced genes in tumor endothelial cells. | Cancer research 20070501 |
| Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells. | Experimental & molecular medicine 20070430 |
| Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum. | British journal of cancer 20070423 |
| Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin. | British journal of cancer 20070423 |
| Hypermethylation and aberrant expression of Wnt antagonist secreted frizzled-related protein 1 in gastric cancer. | World journal of gastroenterology 20070421 |
| Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells. | The Journal of biological chemistry 20070420 |
| Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia. | Blood 20070415 |
| Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential. | Blood 20070415 |
| High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene. | Cancer genetics and cytogenetics 20070415 |
| Epigenetic up-regulation of CXCR4 and CXCL12 expression by 17 beta-estradiol and tamoxifen is associated with formation of DNA methyltransferase 3B4 splice variant in Ishikawa endometrial adenocarcinoma cells. | FEBS letters 20070403 |
| Strategies for achieving transfusion independence in myelodysplastic syndromes. | European journal of oncology nursing : the official journal of European Oncology Nursing Society 20070401 |
| Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines. | Leukemia research 20070401 |
| Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers. | Annals of surgical oncology 20070401 |
| Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites. | Histochemistry and cell biology 20070401 |
| Differential expression of hDAB2IPA and hDAB2IPB in normal tissues and promoter methylation of hDAB2IPA in hepatocellular carcinoma. | Journal of hepatology 20070401 |
| Transcriptional reactivation of murine cytomegalovirus ie gene expression by 5-aza-2'-deoxycytidine and trichostatin A in latently infected cells despite lack of methylation of the major immediate-early promoter. | The Journal of general virology 20070401 |
| 5-aza-2'-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070401 |
| Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas. | Haematologica 20070401 |
| Current treatment options: impact of cytogenetics on the course of myelodysplasia. | Current treatment options in oncology 20070401 |
| Identification of PRTFDC1 silencing and aberrant promoter methylation of GPR150, ITGA8 and HOXD11 in ovarian cancers. | Life sciences 20070327 |
| Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol. | The Journal of biological chemistry 20070323 |
| Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience. | Cancer 20070315 |
| Covalent modification of DNA regulates memory formation. | Neuron 20070315 |
| DNA methylation as a therapeutic target in cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070315 |
| 5-AZA-2'-deoxycytidine in cancer immunotherapy: a mouse to man story. | Cancer research 20070315 |
| Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir. | Cancer letters 20070308 |
| DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. | Molecular pharmacology 20070301 |
| Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer. | The Journal of pathology 20070301 |
| Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia. | Cancer 20070301 |
| Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method. | Nucleic acids research 20070301 |
| Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer. | Cancer science 20070301 |
| Methylation status of the SOCS3 gene in human malignant melanomas. | International journal of oncology 20070301 |
| The myelodysplastic syndromes. | Expert opinion on biological therapy 20070301 |
| Hypermethylation of RASSF1A in human and rhesus placentas. | The American journal of pathology 20070301 |
| RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. | Cancer research 20070301 |
| Myelodysplasia: the good, the fair and the ugly. | Best practice & research. Clinical haematology 20070301 |
| Frequent epigenetic silencing of protocadherin 10 by methylation in multiple haematologic malignancies. | British journal of haematology 20070301 |
| Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells. | Genes to cells : devoted to molecular & cellular mechanisms 20070301 |
| Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway. | The journals of gerontology. Series A, Biological sciences and medical sciences 20070301 |
| Mouse and rat BDNF gene structure and expression revisited. | Journal of neuroscience research 20070215 |
| Igf-2r expression regulated by epigenetic modification and the locus of gene imprinting disrupted in cloned cattle. | Gene 20070215 |
| Activity of decitabine, a hypomethylating agent, in chronic myelomonocytic leukemia. | Cancer 20070215 |
| Methylation status of the Ep-CAM promoter region in human breast cancer cell lines and breast cancer tissue. | Cancer letters 20070208 |
| The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation. | Oncogene 20070208 |
| Inhibition of MHC class II gene expression in uveal melanoma cells is due to methylation of the CIITA gene or an upstream activator. | Experimental and molecular pathology 20070201 |
| Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis. | Cell death and differentiation 20070201 |
| Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. | Carcinogenesis 20070201 |
| Decitabine--bedside to bench. | Critical reviews in oncology/hematology 20070201 |
| Decitabine and vitamin D3 differentially affect hematopoietic transcription factors to induce monocytic differentiation. | International journal of oncology 20070201 |
| Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer. | Cancer science 20070201 |
| Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression. | Experimental hematology 20070201 |
| Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene. | Nucleic acids research 20070201 |
| Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. | Cancer research 20070201 |
| Epigenetic inactivation of the chromosomal stability control genes BRCA1, BRCA2, and XRCC5 in non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070201 |
| Recent experience with decitabine in MDS. | Clinical advances in hematology & oncology : H&O 20070201 |
| [The methylation and mRNA expression of SLC5A8 and TMS1/ASC genes in human glioma]. | Zhonghua yi xue za zhi 20070130 |
| Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. | Oncogene 20070125 |
| Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome. | Cancer 20070115 |
| Lymphangiogenesis and its regulation in human neuroblastoma. | Biochemical and biophysical research communications 20070112 |
| 5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation. | Oncogene 20070104 |
| Aberrant methylation of CDH13 gene in nasopharyngeal carcinoma could serve as a potential diagnostic biomarker. | Oral oncology 20070101 |
| Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. | Blood 20070101 |
| Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis. | Molecular endocrinology (Baltimore, Md.) 20070101 |
| Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. | International journal of cancer 20070101 |
| Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. | International journal of cancer 20070101 |
| High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array. | Human genetics 20070101 |
| DNA methylation of the RIZ1 gene is associated with nuclear accumulation of p53 in prostate cancer. | Cancer science 20070101 |
| Efficacy of DNA hypomethylating capacities of 5-aza-2'-deoxycytidine and its alpha anomer. | Pharmacological research 20070101 |
| Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer. | Cancer science 20070101 |
| Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer. | Oncology reports 20070101 |
| The role of decitabine in the treatment of myelodysplastic syndromes. | Expert opinion on pharmacotherapy 20070101 |
| DNA methylation paradigm shift: 15-lipoxygenase-1 upregulation in prostatic intraepithelial neoplasia and prostate cancer by atypical promoter hypermethylation. | Prostaglandins & other lipid mediators 20070101 |
| Nasopharyngeal carcinoma: molecular biomarker discovery and progress. | Molecular cancer 20070101 |
| Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070101 |
| Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression. | BMC genomics 20070101 |
| Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment. | Cancer research 20070101 |
| Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells. | Molecular cancer 20070101 |
| [Role of epigenetics in the carcinogenesis of head and neck carcinomas - possible new targeted therapy?]. | Laryngo- rhino- otologie 20070101 |
| Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. | Gastroenterology 20070101 |
| Identification of candidate methylation-responsive genes in ovarian cancer. | Molecular cancer 20070101 |
| Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer. | Molecular cancer 20070101 |
| [Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070101 |
| Risk-based management of myelodysplastic syndrome. | Oncology (Williston Park, N.Y.) 20070101 |
| Distinct mechanisms of loss of IFN-gamma mediated HLA class I inducibility in two melanoma cell lines. | BMC cancer 20070101 |
| The effects of DNA methylation and histone deacetylase inhibitors on human papillomavirus early gene expression in cervical cancer, an in vitro and clinical study. | Virology journal 20070101 |
| Sp1/Sp3 and DNA-methylation contribute to basal transcriptional activation of human podoplanin in MG63 versus Saos-2 osteoblastic cells. | BMC molecular biology 20070101 |
| Clinical implications and utility of field cancerization. | Cancer cell international 20070101 |
| Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta. | BMC cancer 20070101 |
| DNA methyltransferase inhibitors for cancer therapy. | Cancer journal (Sudbury, Mass.) 20070101 |
| Utilization of chromatin remodeling agents for lung cancer therapy. | Cancer journal (Sudbury, Mass.) 20070101 |
| Methylation-mediated silencing of genes is not altered by selenium treatment of prostate cancer cells. | Anticancer research 20070101 |
| 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high. | BMC cancer 20070101 |
| Methylation of the BIN1 gene promoter CpG island associated with breast and prostate cancer. | Journal of carcinogenesis 20070101 |
| New drugs: paliperidone, dasatinib, and decitabine. | Journal of the American Pharmacists Association : JAPhA 20070101 |
| Important roles of multiple Sp1 binding sites and epigenetic modifications in the regulation of the methionine sulfoxide reductase B1 (MsrB1) promoter. | BMC molecular biology 20070101 |
| Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing. | BMC genomics 20070101 |
| Epigenetic regulation of bone morphogenetic protein-6 gene expression in breast cancer cells. | The Journal of steroid biochemistry and molecular biology 20070101 |
| Complement susceptibility in glutamine deprived breast cancer cells. | Cell division 20070101 |
| Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma. | BMC cancer 20070101 |
| Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2. | Biochimica et biophysica acta 20070101 |
| Identification of methylation-associated gene expression in neuroendocrine pancreatic tumor cells. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20070101 |
| Correlation between CpG methylation profiles and hormone receptor status in breast cancers. | Breast cancer research : BCR 20070101 |
| The effect of body weight on altered expression of nuclear receptors and cyclooxygenase-2 in human colorectal cancers. | Nutrition journal 20070101 |
| Decitabine and sickle cell disease: molecular therapy for a molecular disease. | Pediatric hematology and oncology 20070101 |
| Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells in vitro and in xenografts: identification of apoptotic genes as targets for demethylation. | Cancer cell international 20070101 |
| In vivo transcriptional targeting into the retinal vasculature using recombinant baculovirus carrying the human flt-1 promoter. | Virology journal 20070101 |
| DNA methylation state is preserved in the sperm-derived pronucleus of the pig zygote. | The International journal of developmental biology 20070101 |
| Modulation of HLA-G expression. | Neoplasma 20070101 |
| Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies. | BMC evolutionary biology 20070101 |
| Tumor-specific methylation of the 8p22 tumor suppressor gene DLC1 is an epigenetic biomarker for Hodgkin, nasal NK/T-cell and other types of lymphomas. | Epigenetics 20070101 |
| The effects of nucleoside analogues on promoter methylation of selected tumor suppressor genes in MCF-7 and MDA-MB-231 breast cancer cell lines. | Nucleosides, nucleotides & nucleic acids 20070101 |
| DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer. | Cancer immunity 20070101 |
| A role for DNA methylation in regulating the growth suppressor PMEPA1 gene in prostate cancer. | Epigenetics 20070101 |
| Epigenetic and genetic alterations of the EDNRB gene in nasopharyngeal carcinoma. | Oncology 20070101 |
| Targeted brain tumor treatment-current perspectives. | Drug target insights 20070101 |
| Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer. | British journal of cancer 20061218 |
| 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer). | Biochemical and biophysical research communications 20061215 |
| RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma. | Cancer 20061215 |
| Low-dose decitabine and high-risk MDS. | Blood 20061215 |
| Aberrant DNA demethylation in promoter region and aberrant expression of mRNA of PAX4 gene in hematologic malignancies. | Leukemia research 20061201 |
| Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression. | Journal of leukocyte biology 20061201 |
| Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1). | The Journal of pathology 20061201 |
| DNA methylation-dependent silencing of CST6 in human breast cancer cell lines. | Laboratory investigation; a journal of technical methods and pathology 20061201 |
| Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma. | Neuroscience research 20061201 |
| Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. | Gastroenterology 20061201 |
| Epigenetic silencing of novel tumor suppressors in malignant melanoma. | Cancer research 20061201 |
| A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. | PLoS medicine 20061201 |
| Association of DNA methylation and epigenetic inactivation of RASSF1A and beta-catenin with metastasis in small bowel carcinoid tumors. | Endocrine 20061201 |
| [Expression of ER alpha in chemically induced MDA-MB-435 cells and its responsiveness to endocrine]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061201 |
| [Demethylation of estrogen receptor gene and its re-expression in estrogen receptor-negative breast]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061201 |
| Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes. | Therapeutics and clinical risk management 20061201 |
| Epigenetic control of CTCFL/BORIS and OCT4 expression in urogenital malignancies. | Biochemical pharmacology 20061130 |
| Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction. | International journal of cancer 20061115 |
| Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia. | Blood 20061115 |
| The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation. | International journal of cancer 20061115 |
| Epigenetic regulation of tumor endothelial cell anergy: silencing of intercellular adhesion molecule-1 by histone modifications. | Cancer research 20061115 |
| Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061115 |
| Decitabine (Dacogen) for myelodysplastic syndromes. | The Medical letter on drugs and therapeutics 20061106 |
| Effect of histone deacetylase inhibitor LAQ824 on antineoplastic action of 5-Aza-2'-deoxycytidine (decitabine) on human breast carcinoma cells. | Cancer chemotherapy and pharmacology 20061101 |
| Hypermethylation of the GATA gene family in esophageal cancer. | International journal of cancer 20061101 |
| Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells. | Toxicology and applied pharmacology 20061101 |
| Epigenetic regulation of human trophoblastic cell migration and invasion. | Endocrinology 20061101 |
| Aberrant promoter methylation of the ABCG2 gene in renal carcinoma. | Molecular and cellular biology 20061101 |
| Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer. | Journal of molecular medicine (Berlin, Germany) 20061101 |
| Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies. | American journal of human genetics 20061101 |
| IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1. | Journal of Zhejiang University. Science. B 20061101 |
| Methylation of multiple genes in gastric glands with intestinal metaplasia: A disorder with polyclonal origins. | The American journal of pathology 20061101 |
| Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer. | Cancer research 20061101 |
| A repressive epigenetic domino effect confers susceptibility to breast epithelial cell transformation: implications for predicting breast cancer risk. | Cancer research 20061101 |
| Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression. | Cancer research 20061101 |
| Decitabine. | Nature reviews. Drug discovery 20061101 |
| [Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20061101 |
| Targeting the epigenome for the treatment of thoracic malignancies. | Thoracic surgery clinics 20061101 |
| Genetic abnormalities as targets for molecular therapies in myelodysplastic syndromes. | Annals of the New York Academy of Sciences 20061101 |
| Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer. | Cancer biology & therapy 20061101 |
| Methylation of the mouse DIx5 and Osx gene promoters regulates cell type-specific gene expression. | Molecules and cells 20061031 |
| [Expression of S100A2 in secondarily radioresistant pancreatic cancer cells and significance thereof]. | Zhonghua yi xue za zhi 20061031 |
| Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation. | Cancer letters 20061028 |
| Epigenetic cancer therapy makes headway. | Journal of the National Cancer Institute 20061018 |
| DNA mismatch repair as an effector for promoting phorbol ester-induced apoptotic DNA damage and cell killing: implications in tumor promotion. | International journal of cancer 20061015 |
| Analysis of genes upregulated by the demethylating agent 5-aza-2'-deoxycytidine in gastric cancer cell lines. | International journal of cancer 20061001 |
| Differentially methylated alleles in a distinct region of the human interleukin-1alpha promoter are associated with allele-specific expression of IL-1alpha in CD4+ T cells. | Blood 20061001 |
| PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter. | Annals of hematology 20061001 |
| A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system. | International journal of oncology 20061001 |
| An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis. | Cancer research 20061001 |
| Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061001 |
| Improved DNA methylation analysis via enrichment of demethylated cells expressing an X-inactivated transgene. | BioTechniques 20061001 |
| DNA hypermethylation of myeloid cells, a novel therapeutic target in MDS and AML. | Current pharmaceutical biotechnology 20061001 |
| [SHP-1 gene's methylation status of Daudi lymphoma cell and the demethylation effect of 5-aza-2'-deoxycytidine]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20061001 |
| Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues. | World journal of gastroenterology 20060921 |
| High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. | Journal of clinical pathology 20060901 |
| Plakoglobin is differentially expressed in alveolar and embryonal rhabdomyosarcoma and is regulated by DNA methylation and histone acetylation. | Carcinogenesis 20060901 |
| IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo. | Blood 20060901 |
| Human astrocytes express 14-3-3 sigma in response to oxidative and DNA-damaging stresses. | Neuroscience research 20060901 |
| Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma. | Cancer science 20060901 |
| Aberrant maspin expression in human endometrial cancer. | Cancer science 20060901 |
| Regulation of DNA methylation on the expression of the FHIT gene contributes to cervical carcinoma cell tumorigenesis. | Oncology reports 20060901 |
| Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma. | Leukemia 20060901 |
| Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells. | Experimental hematology 20060901 |
| A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer. | Cancer research 20060901 |
| Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton. | The journals of gerontology. Series A, Biological sciences and medical sciences 20060901 |
| The genomics of new drugs in sickle cell disease. | Pharmacogenomics 20060901 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060901 |
| 5-Aza-2'-deoxycytidine and IFN-gamma cooperate to sensitize for TRAIL-induced apoptosis by upregulating caspase-8. | Oncogene 20060824 |
| Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. | Oncogene 20060817 |
| Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression. | Cancer research 20060815 |
| Characterization and expression of CT45 in Hodgkin's lymphoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060815 |
| Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation. | Oncogene 20060810 |
| Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060810 |
| Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing. | FEBS letters 20060807 |
| Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. | The Journal of biological chemistry 20060804 |
| CpG island promoter methylation and silencing of 14-3-3sigma gene expression in LNCaP and Tramp-C1 prostate cancer cell lines is associated with methyl-CpG-binding protein MBD2. | Oncogene 20060803 |
| Epigenetic regulation of maspin expression in human ovarian carcinoma cells. | Gynecologic oncology 20060801 |
| Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia. | Leukemia research 20060801 |
| p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation. | Journal of cellular biochemistry 20060801 |
| Comparison of five prognostic scoring systems, the French-American-British (FAB) and World Health Organization (WHO) classifications in patients with myelodysplastic syndromes: Results of a single-center analysis. | Annals of hematology 20060801 |
| DNA methylation alterations in urothelial carcinoma. | Cancer biology & therapy 20060801 |
| Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma. | Cancer 20060801 |
| Investigational agents for sickle cell disease. | Expert opinion on investigational drugs 20060801 |
| Epigenetic inactivation of the dioxin-responsive cytochrome P4501A1 gene in human prostate cancer. | Cancer research 20060801 |
| Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. | Cancer research 20060801 |
| Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060801 |
| Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. | Oncogene 20060706 |
| Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice. | International journal of cancer 20060701 |
| The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells. | Human reproduction (Oxford, England) 20060701 |
| Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. | Carcinogenesis 20060701 |
| Second complete remission in an elderly patient with acute myeloid leukemia retreated with decitabine. | American journal of hematology 20060701 |
| A role for the WWOX gene in prostate cancer. | Cancer research 20060701 |
| RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. | Cancer research 20060701 |
| Epigenetic silencing of the PTEN gene in melanoma. | Cancer research 20060701 |
| Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. | Cancer research 20060701 |
| Estrogen receptor-alpha methylation predicts melanoma progression. | Cancer research 20060701 |
| Methylation of neutral endopeptidase 24.11 promoter in rat hepatocellular carcinoma. | Cancer science 20060701 |
| Downregulation of DBC1 expression in acute lymphoblastic leukaemia is mediated by aberrant methylation of its promoter. | British journal of haematology 20060701 |
| Managing patients with low-risk MDS. | Clinical advances in hematology & oncology : H&O 20060701 |
| Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. | International journal of cancer 20060615 |
| Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas. | Cancer research 20060615 |
| Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes. | Cancer research 20060615 |
| Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis. | Oncogene 20060608 |
| GnT-V expression and metastatic phenotypes in macrophage-melanoma fusion hybrids is down-regulated by 5-Aza-dC: evidence for methylation sensitive, extragenic regulation of GnT-V transcription. | Gene 20060607 |
| Sequential gene expression changes in cancer cell lines after treatment with the demethylation agent 5-Aza-2'-deoxycytidine. | Cancer 20060601 |
| Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. | Alcoholism, clinical and experimental research 20060601 |
| Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. | Cancer cell 20060601 |
| Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. | Biological chemistry 20060601 |
| The epigenetic basis for the aberrant expression of kallikreins in human cancers. | Biological chemistry 20060601 |
| [Disfigurement of p16INK4A gene expression in development of ovarian cancer and the mechanism]. | Zhonghua fu chan ke za zhi 20060601 |
| AKAP12alpha is associated with promoter methylation in lung cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20060601 |
| Methylation of the human papillomavirus-18 L1 gene: a biomarker of neoplastic progression? | Virology 20060525 |
| Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus. | Oncogene 20060518 |
| Identification of novel target genes by an epigenetic reactivation screen of renal cancer. | Cancer research 20060515 |
| Silencing of bidirectional promoters by DNA methylation in tumorigenesis. | Cancer research 20060515 |
| DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia. | Cancer research 20060515 |
| Regulation of high molecular weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells. | Oncogene 20060511 |
| Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer. | Oncogene 20060511 |
| Differential 14-3-3 sigma DNA methylation and expression in c-myc- and activated H-ras-transformed cells under r- and K-selection. | Cancer letters 20060508 |
| Characterization of baculovirus Autographa californica multiple nuclear polyhedrosis virus infection in mammalian cells. | Biochemical and biophysical research communications 20060505 |
| The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding. | Carcinogenesis 20060501 |
| Aberrant methylation of RASGRF2 and RASSF1A in human non-small cell lung cancer. | Oncology reports 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Imprinting at the SMPD1 locus: implications for acid sphingomyelinase-deficient Niemann-Pick disease. | American journal of human genetics 20060501 |
| Ex vivo modulation of response to prednisolone in childhood acute lymphoblastic leukaemia. | British journal of haematology 20060501 |
| Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing. | Molecular and cellular biology 20060501 |
| Epigenetic inactivation of Betaig-h3 gene in human cancer cells. | Cancer research 20060501 |
| Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. | Molecular cancer research : MCR 20060501 |
| Promoter hypermethylation of a novel gene, ZHX2, in hepatocellular carcinoma. | American journal of clinical pathology 20060501 |
| [Transcription regulation of 5-Aza-2'-deoxycytidine on maspin gene demethylation in RKO human colorectal cell line]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20060501 |
| New strategies in chronic myeloid leukemia. | International journal of hematology 20060501 |
| Review: recent clinical trials in epigenetic therapy. | Reviews on recent clinical trials 20060501 |
| Frequent epigenetic silencing of the bone morphogenetic protein 2 gene through methylation in gastric carcinomas. | Oncogene 20060427 |
| Epigenetics as a mechanism driving polygenic clinical drug resistance. | British journal of cancer 20060424 |
| Potential clinical relevance of Eph receptors and ephrin ligands expressed in prostate carcinoma cell lines. | Biochemical and biophysical research communications 20060421 |
| Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b. | Oncogene 20060420 |
| Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. | Cancer 20060415 |
| Drug therapy for myelodysplastic syndrome: building evidence for action. | Cancer 20060415 |
| Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2'-deoxycytidine retreatment in high-risk myelodysplasia patients. | Cancer 20060415 |
| Regulatory factor for X-box family proteins differentially interact with histone deacetylases to repress collagen alpha2(I) gene (COL1A2) expression. | The Journal of biological chemistry 20060407 |
| Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2. | Oncogene 20060406 |
| Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications. | Journal of cellular physiology 20060401 |
| Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma. | Cell death and differentiation 20060401 |
| N-methyl-D-aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-suppressive activity in human esophageal cancer. | Cancer research 20060401 |
| A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons. | Cancer research 20060401 |
| Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. | Cancer research 20060401 |
| PGP9.5 methylation in diffuse-type gastric cancer. | Cancer research 20060401 |
| Gene promoter hypermethylation in mouse lung tumors. | Molecular cancer research : MCR 20060401 |
| Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060401 |
| [Myelodysplastic syndromes--new treatment options]. | Medizinische Klinik (Munich, Germany : 1983) 20060322 |
| Epigenetic processes play a major role in B-cell-specific gene silencing in classical Hodgkin lymphoma. | Blood 20060315 |
| Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer. | Journal of the National Cancer Institute 20060315 |
| Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060315 |
| Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1. | Biochemical and biophysical research communications 20060310 |
| Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines. | Biochemical and biophysical research communications 20060310 |
| Treatment of myelodysplastic syndrome with a DNA methyltransferase inhibitor: lack of evidence for induction of chromosomal instability. | Leukemia research 20060301 |
| Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing. | Leukemia research 20060301 |
| Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS. | American journal of physiology. Endocrinology and metabolism 20060301 |
| RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301 |
| Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. | Cancer biology & therapy 20060301 |
| Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting Fanconi anemia-BRCA pathway. | Cancer biology & therapy 20060301 |
| Aberrant promoter hypermethylation and silencing of the critical 3p21 tumour suppressor gene, RASSF1A, in Chinese oesophageal squamous cell carcinoma. | International journal of oncology 20060301 |
| Distinct gene expression profiles in immortalized human urothelial cells exposed to inorganic arsenite and its methylated trivalent metabolites. | Environmental health perspectives 20060301 |
| Expression of RASSF1A, an epigenetically silenced tumor suppressor, overcomes resistance to apoptosis induction by interferons. | Cancer research 20060301 |
| Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. | Cancer research 20060301 |
| Effect of methylation-associated silencing of the death-associated protein kinase gene on nasopharyngeal carcinoma. | Anti-cancer drugs 20060301 |
| Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060301 |
| Effect of 5-aza-2'-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin promoters in Papio anubis. | Experimental hematology 20060301 |
| Meiotically stable natural epialleles of Sadhu, a novel Arabidopsis retroposon. | PLoS genetics 20060301 |
| Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. | PLoS genetics 20060301 |
| Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells. | Human pathology 20060301 |
| Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood. | Oncogene 20060216 |
| Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. | Oncogene 20060216 |
| Genetic and epigenetic inactivation of LTF gene at 3p21.3 in lung cancers. | International journal of cancer 20060215 |
| PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060215 |
| Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas. | Oncogene 20060209 |
| Transcriptional silencing of EphB6 receptor tyrosine kinase in invasive breast carcinoma cells and detection of methylated promoter by methylation specific PCR. | Biochemical and biophysical research communications 20060203 |
| Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer. | The Prostate 20060201 |
| Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia. | Leukemia 20060201 |
| Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer. | International journal of oncology 20060201 |
| A novel mechanism for acquired cisplatin-resistance: suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells. | International journal of oncology 20060201 |
| Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents. | Experimental hematology 20060201 |
| Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R. | The Journal of endocrinology 20060201 |
| Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060201 |
| Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation. | PLoS genetics 20060201 |
| The hematologic response to anti-apoptotic cytokine therapy: results of pentoxifylline, ciprofloxacin, and dexamethasone treatment for patients with myelodysplastic syndrome. | Journal of Korean medical science 20060201 |
| Angiostatic activity of DNA methyltransferase inhibitors. | Molecular cancer therapeutics 20060201 |
| Epigenetics provides a new generation of oncogenes and tumour-suppressor genes. | British journal of cancer 20060130 |
| CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia. | Cancer research 20060115 |
| De novo induction of a cancer/testis antigen by 5-aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model. | Cancer research 20060115 |
| Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060115 |
| Heterogeneous expression of GAGE, NY-ESO-1, MAGE-A and SSX proteins in esophageal cancer: Implications for immunotherapy. | International journal of cancer 20060101 |
| 5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation. | Leukemia research 20060101 |
| Effects of 5-aza-2'-deoxycytidine on proliferation, differentiation and p15/INK4b regulation of human hematopoietic progenitor cells. | Leukemia 20060101 |
| Epigenetic inactivation of the RUNX3 gene in lung cancer. | Oncology reports 20060101 |
| Aberrant promoter methylation of EDNRB in lung cancer in Taiwan. | Oncology reports 20060101 |
| Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. | Cancer science 20060101 |
| Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer. | Cancer research 20060101 |
| Stat1 expression is not sufficient to regulate the interferon signaling pathway in cellular immortalization. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20060101 |
| Current therapy of sickle cell disease. | Haematologica 20060101 |
| Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060101 |
| The myelodysplastic syndromes: diagnosis and treatment. | Mayo Clinic proceedings 20060101 |
| Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines. | Cancer cell international 20060101 |
| Epigenetics and airways disease. | Respiratory research 20060101 |
| Hydralazine target: from blood vessels to the epigenome. | Journal of translational medicine 20060101 |
| Myelodysplasia: when to treat and how. | Best practice & research. Clinical haematology 20060101 |
| Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2'-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification method. | Rapid communications in mass spectrometry : RCM 20060101 |
| In vivo-in vitro toxicogenomic comparison of TCDD-elicited gene expression in Hepa1c1c7 mouse hepatoma cells and C57BL/6 hepatic tissue. | BMC genomics 20060101 |
| Role of transcription factor Sp1 and CpG methylation on the regulation of the human podocalyxin gene promoter. | BMC molecular biology 20060101 |
| Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression. | Molecular cancer 20060101 |
| Immunodeficiency, centromeric region instability, facial anomalies syndrome (ICF). | Orphanet journal of rare diseases 20060101 |
| The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines. | BMC cancer 20060101 |
| Decitabine: in myelodysplastic syndromes. | Drugs 20060101 |
| Decitabine in myelodysplastic syndromes: viewpoints. | Drugs 20060101 |
| The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. | Molecular cancer 20060101 |
| Methylation mediated silencing of TMS1/ASC gene in prostate cancer. | Molecular cancer 20060101 |
| Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation. | BMC genomics 20060101 |
| Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine. | Journal of translational medicine 20060101 |
| The role of DNA methylation in cancer development. | Folia histochemica et cytobiologica 20060101 |
| Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review. | Molecular cancer 20060101 |
| Alteration of DNA methylation status in K562 and MCF-7 cancer cell lines by nucleoside analogues. | Nucleosides, nucleotides & nucleic acids 20060101 |
| Induction of fetal hemoglobin in the treatment of sickle cell disease. | Hematology. American Society of Hematology. Education Program 20060101 |
| Clinical issues in the management of patients with myelodysplasia. | Hematology. American Society of Hematology. Education Program 20060101 |
| ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis. | Cellular oncology : the official journal of the International Society for Cellular Oncology 20060101 |
| A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer. | PloS one 20060101 |
| Up-regulation of HLA class-I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating agent hydralazine and the histone deacetylase inhibitor valproic acid. | Journal of translational medicine 20060101 |
| New treatment for rare bone marrow condition. | FDA consumer 20060101 |
| Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma. | Oncology 20060101 |
| Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma. | Oncology research 20060101 |
| The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors. | Oncology 20060101 |
| Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells. | Epigenetics 20060101 |
| 5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells. | Cancer letters 20051218 |
| Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction. | Cancer research 20051215 |
| The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia. | British journal of cancer 20051212 |
| Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines. | Molecular carcinogenesis 20051201 |
| Decitabine activates specific caspases downstream of p73 in myeloid leukemia. | Annals of hematology 20051201 |
| An epigenetic approach to the treatment of advanced MDS; the experience with the DNA demethylating agent 5-aza-2'-deoxycytidine (decitabine) in 177 patients. | Annals of hematology 20051201 |
| Decitabine: a historical review of the development of an epigenetic drug. | Annals of hematology 20051201 |
| Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts. | Annals of hematology 20051201 |
| Clinical experience with decitabine in North American patients with myelodysplastic syndrome. | Annals of hematology 20051201 |
| In vivo effects of decitabine in myelodysplasia and acute myeloid leukemia: review of cytogenetic and molecular studies. | Annals of hematology 20051201 |
| Quantification of outpatient management and hospitalization of patients with high-risk myelodysplastic syndrome treated with low-dose decitabine. | Annals of hematology 20051201 |
| The hematopathological basis for studying effects of the demethylating agent 5-aza-2'-deoxycytidine (decitabine) in myelodysplasia. | Annals of hematology 20051201 |
| BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy. | Cancer research 20051201 |
| Methylation inhibitor therapy in the treatment of myelodysplastic syndrome. | Nature clinical practice. Oncology 20051201 |
| Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: dose, duration, and patient selection. | Nature clinical practice. Oncology 20051201 |
| Inhibitors of DNA methylation: beyond myelodysplastic syndromes. | Nature clinical practice. Oncology 20051201 |
| DNA methylation and gene silencing in cancer. | Nature clinical practice. Oncology 20051201 |
| [The synergistic inhibitory effect of 5-aza-2-deoxycytidine and Tamoxifen on estrogen receptor alpha negative breast cancer cell lines in vitro]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20051201 |
| Cancer-testis antigen expression in bladder cancer. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20051201 |
| Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers. | Oncogene 20051124 |
| Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors. | Cancer research 20051115 |
| Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification. | Cancer research 20051115 |
| Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies. | Carcinogenesis 20051101 |
| Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells. | Cancer chemotherapy and pharmacology 20051101 |
| The epigenome as a molecular marker and target. | Cancer 20051101 |
| Epigenetic control of highly homologous killer Ig-like receptor gene alleles. | Journal of immunology (Baltimore, Md. : 1950) 20051101 |
| Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment. | Cellular and molecular life sciences : CMLS 20051101 |
| Consistent transcriptional silencing of 35S-driven transgenes in gentian. | The Plant journal : for cell and molecular biology 20051101 |
| Tissue-specific and de novo promoter methylation of the mouse glucose transporter 2. | Biological & pharmaceutical bulletin 20051101 |
| The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. | Molecular cancer therapeutics 20051101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20051101 |
| New agents in the treatment of MDS. | Clinical advances in hematology & oncology : H&O 20051101 |
| Coordinated transcriptional regulation of calmegin,a testis-specific molecular chaperon, by histone deacetylase and CpG methyltransferase. | Experimental & molecular medicine 20051031 |
| DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation. | Cancer 20051015 |
| Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051015 |
| Differential promotion of glutamate transporter expression and function by glucocorticoids in astrocytes from various brain regions. | The Journal of biological chemistry 20051014 |
| Aberrant methylation of FBN2 in human non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20051001 |
| Epigenetic-mediated upregulation of progesterone receptor B gene in endometrial cancer cell lines. | Gynecologic oncology 20051001 |
| DNA methylation is required for silencing of ant4, an adenine nucleotide translocase selectively expressed in mouse embryonic stem cells and germ cells. | Stem cells (Dayton, Ohio) 20051001 |
| DNA methyltransferase-3a interacts with p53 and represses p53-mediated gene expression. | Cancer biology & therapy 20051001 |
| The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents. | International journal of oncology 20051001 |
| 5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines. | Oncology reports 20051001 |
| 5-azacytidine and decitabine monotherapies of myelodysplastic disorders. | The Annals of pharmacotherapy 20051001 |
| Trapped in action: direct visualization of DNA methyltransferase activity in living cells. | Nature methods 20051001 |
| Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia. | British journal of haematology 20051001 |
| Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051001 |
| Activator protein 2alpha status determines the chemosensitivity of cancer cells: implications in cancer chemotherapy. | Cancer research 20051001 |
| The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer. | Cancer research 20051001 |
| Epigenetic drugs: a longstanding story. | Seminars in oncology 20051001 |
| Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine). | Seminars in oncology 20051001 |
| Innovative approaches to the clinical development of DNA methylation inhibitors as epigenetic remodeling drugs. | Seminars in oncology 20051001 |
| Clinical development of decitabine as a prototype for an epigenetic drug program. | Seminars in oncology 20051001 |
| Epigenetic treatment of hematopoietic malignancies: in vivo targets of demethylating agents. | Seminars in oncology 20051001 |
| [Inhibitory effect of 5-Aza-2'-deoxycytidine on human nasopharyngeal carcinoma xenograft in nude mice]. | Ai zheng = Aizheng = Chinese journal of cancer 20051001 |
| Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer. | Molecular cancer therapeutics 20051001 |
| Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine. | Molecular cancer therapeutics 20051001 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20051001 |
| Epigenetic therapy with decitabine for myelodysplasia and leukemia. | Future oncology (London, England) 20051001 |
| Mapping of the methylation pattern of the MUC2 promoter in pancreatic cancer cell lines, using bisulfite genomic sequencing. | Cancer letters 20050928 |
| Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. | Oncogene 20050922 |
| Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation. | Oncogene 20050915 |
| The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer. | Cancer research 20050915 |
| GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
| The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
| Insensitivity to transforming growth factor-beta results from promoter methylation of cognate receptors in human prostate cancer cells (LNCaP). | Molecular endocrinology (Baltimore, Md.) 20050901 |
| Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: implications for pathogenesis and therapeutic approach. | Oncogene 20050901 |
| Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters. | Cancer research 20050901 |
| Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes. | Cancer research 20050901 |
| Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells. | Cancer research 20050901 |
| Strategies for biology- and molecular-based treatment of myelodysplastic syndromes. | Current drug targets 20050901 |
| DNA methylation in the treatment of hematologic malignancies. | Clinical advances in hematology & oncology : H&O 20050901 |
| The identification of senescence-specific genes during the induction of senescence in prostate cancer cells. | Neoplasia (New York, N.Y.) 20050901 |
| CpG methylation of the PAI-1 gene 5'-flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines. | Thrombosis and haemostasis 20050901 |
| Hypermethylation of the RUNX3 gene in hepatocellular carcinoma. | Experimental & molecular medicine 20050831 |
| Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis. | Circulation 20050830 |
| Downregulation of EphA7 by hypermethylation in colorectal cancer. | Oncogene 20050825 |
| Characterization of DNA demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome. | Cancer research 20050815 |
| P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050815 |
| Granulocyte-macrophage colony-stimulating factor induces de novo methylation of the p15 CpG island in hematopoietic cells. | Cytokine 20050807 |
| Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome. | Leukemia 20050801 |
| Notch 2-positive progenitors with the intrinsic ability to give rise to pancreatic ductal cells. | Laboratory investigation; a journal of technical methods and pathology 20050801 |
| Epigenetic inactivation of CHFR in nasopharyngeal carcinoma through promoter methylation. | Molecular carcinogenesis 20050801 |
| TP53 promoter methylation in human gliomas. | Acta neuropathologica 20050801 |
| Halogenated thymidine analogues restore the expression of silenced genes without demethylation. | Cancer research 20050801 |
| Methylation-associated silencing of death-associated protein kinase gene in laryngeal squamous cell cancer. | The Laryngoscope 20050801 |
| Epstein-Barr virus and p16INK4A methylation in squamous cell carcinoma and precancerous lesions of the cervix uteri. | Journal of Korean medical science 20050801 |
| Conventional and new treatment options for myelofibrosis with myeloid metaplasia. | Seminars in oncology 20050801 |
| Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers. | Neoplasia (New York, N.Y.) 20050801 |
| Epigenetic silencing of TCEAL7 (Bex4) in ovarian cancer. | Oncogene 20050728 |
| Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta. | Oncogene 20050728 |
| Promoter characterization of Semaphorin SEMA3F, a tumor suppressor gene. | Biochimica et biophysica acta 20050725 |
| Patterned CpG methylation of silenced B cell gene promoters in classical Hodgkin lymphoma-derived and primary effusion lymphoma cell lines. | Journal of molecular biology 20050722 |
| Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies. | Oncogene 20050714 |
| Aberrant methylation of Reprimo in human malignancies. | International journal of cancer 20050701 |
| Release of methyl CpG binding proteins and histone deacetylase 1 from the Estrogen receptor alpha (ER) promoter upon reactivation in ER-negative human breast cancer cells. | Molecular endocrinology (Baltimore, Md.) 20050701 |
| Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells. | Biochemical pharmacology 20050701 |
| DNA methylation disturbances as novel therapeutic target in lung cancer: preclinical and clinical results. | Critical reviews in oncology/hematology 20050701 |
| CpG methylation at promoter site -140 inactivates TGFbeta2 receptor gene in prostate cancer. | Cancer 20050701 |
| Resistance to Fas-mediated apoptosis is restored by cycloheximide through the downregulation of cellular FLIPL in NK/T-cell lymphoma. | Laboratory investigation; a journal of technical methods and pathology 20050701 |
| Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid. | Leukemia research 20050701 |
| Hypermethylation patterns in the Fhit regulatory region are tissue specific. | Molecular carcinogenesis 20050701 |
| Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms. | Cancer biology & therapy 20050701 |
| Epigenetic down-regulation of CDKN1C/p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050701 |
| Introduction: emerging role of epigenetic therapy: focus on decitabine. | Seminars in hematology 20050701 |
| Decitabine dosing schedules. | Seminars in hematology 20050701 |
| Decitabine in myelodysplastic syndromes. | Seminars in hematology 20050701 |
| Decitabine in acute myeloid leukemia. | Seminars in hematology 20050701 |
| Decitabine in chronic leukemias. | Seminars in hematology 20050701 |
| Pharmacology of 5-Aza-2'-deoxycytidine (decitabine). | Seminars in hematology 20050701 |
| Induction of HLA-G expression in a melanoma cell line OCM-1A following the treatment with 5-aza-2'-deoxycytidine. | Cell research 20050701 |
| Junctional recruitment of mammalian Scribble relies on E-cadherin engagement. | Oncogene 20050623 |
| Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells. | The Journal of biological chemistry 20050617 |
| Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610 |
| TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610 |
| Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610 |
| Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk. | Oncogene 20050609 |
| Collagen alpha1(I) gene (COL1A1) is repressed by RFX family. | The Journal of biological chemistry 20050603 |
| Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer. | Genes, chromosomes & cancer 20050601 |
| Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre- and mature B lymphocytes. | International immunology 20050601 |
| Cyclin D1 gene activation in human myeloma cells is independent of DNA hypomethylation or histone hyperacetylation. | Experimental hematology 20050601 |
| Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation. | Cancer research 20050601 |
| Methylation silencing of the Apaf-1 gene in acute leukemia. | Molecular cancer research : MCR 20050601 |
| Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer. | Molecular cancer research : MCR 20050601 |
| 5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia. | International journal of cancer 20050501 |
| Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. | European journal of human genetics : EJHG 20050501 |
| Constant IFNgamma mRNA to protein ratios in cord and adult blood T cells suggests regulation of IFNgamma expression in cord blood T cells occurs at the transcriptional level. | Clinical and experimental immunology 20050501 |
| Loss of caspase-1 gene expression in human gastric carcinomas and cell lines. | International journal of oncology 20050501 |
| SWI/SNF chromatin-remodeling factors induce changes in DNA methylation to promote transcriptional activation. | Cancer research 20050501 |
| RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression. | Cancer research 20050501 |
| Discovery of epigenetically masked tumor suppressor genes in endometrial cancer. | Molecular cancer research : MCR 20050501 |
| Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death. | Journal of gastroenterology 20050501 |
| The controversial denouement of vertebrate DNA methylation research. | Biochemistry. Biokhimiia 20050501 |
| Methylation of CpG islands in the rat 7-dehydrocholesterol reductase promoter suppresses transcriptional activation. | Molecules and cells 20050430 |
| De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine. | Oncogene 20050428 |
| Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation. | British journal of cancer 20050425 |
| Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase. | The Journal of biological chemistry 20050422 |
| Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers. | Human molecular genetics 20050415 |
| Co-culture of human CD34+ cells with mesenchymal stem cells increases the survival of CD34+ cells against the 5-aza-deoxycytidine- or trichostatin A-induced cell death. | Biochemical and biophysical research communications 20050415 |
| Promoter methylation of DAL-1/4.1B predicts poor prognosis in non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050415 |
| Methylation and acetylation characteristics of cloned bovine embryos from donor cells treated with 5-aza-2'-deoxycytidine. | Biology of reproduction 20050401 |
| Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. | The Journal of clinical endocrinology and metabolism 20050401 |
| Epigenetic and genetic alterations of p33ING1b in ovarian cancer. | Carcinogenesis 20050401 |
| Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells. | International journal of oncology 20050401 |
| Methylthioadenosine phosphorylase gene is silenced by promoter hypermethylation in human lymphoma cell line DHL-9: another mechanism of enzyme deficiency. | International journal of oncology 20050401 |
| Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines. | International journal of oncology 20050401 |
| Status of reduced expression and hypermethylation of the APC tumor suppressor gene in human oral squamous cell carcinoma. | International journal of molecular medicine 20050401 |
| Hypermethylation of NAD(P)H: quinone oxidoreductase 1 (NQO1) gene in human hepatocellular carcinoma. | Journal of hepatology 20050401 |
| Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells. | Cancer research 20050401 |
| Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells. | Cancer research 20050401 |
| Frequent methylation of eyes absent 4 gene in Barrett's esophagus and esophageal adenocarcinoma. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050401 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20050401 |
| [Frequent epigenetic inactivation of XAF1 by promotor hypermethylation in human colon cancers]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20050401 |
| [Analysis of the methylation in the promoter of LRP15 gene and its expression]. | Zhongguo shi yan xue ye xue za zhi 20050401 |
| Epigenetic hypothesis tests for methylation and acetylation in a triple microarray system. | Journal of computational biology : a journal of computational molecular cell biology 20050401 |
| Aberrant CpG island hypermethylation profile is associated with atypical and anaplastic meningiomas. | Human pathology 20050401 |
| Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells. | Oncogene 20050331 |
| Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour. | British journal of cancer 20050328 |
| Epigenetic inactivation of the human sprouty2 (hSPRY2) homologue in prostate cancer. | Oncogene 20050324 |
| Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays. | Cancer research 20050315 |
| Functional Loss of the gamma-catenin gene through epigenetic and genetic pathways in human prostate cancer. | Cancer research 20050315 |
| Regulation of replication at the R/G chromosomal band boundary and pericentromeric heterochromatin of mammalian cells. | Experimental cell research 20050310 |
| Cell type-specific regulation of the TGF-beta-responsive alpha2(I) collagen gene by CpG methylation. | Journal of cellular physiology 20050301 |
| Expression of aquaporin-5 in and fluid secretion from immortalized human salivary gland ductal cells by treatment with 5-aza-2'-deoxycytidine: a possibility for improvement of xerostomia in patients with Sjögren's syndrome. | Laboratory investigation; a journal of technical methods and pathology 20050301 |
| Promoter hypermethylation and inactivation of O(6)-methylguanine-DNA methyltransferase in esophageal squamous cell carcinomas and its reactivation in cell lines. | International journal of oncology 20050301 |
| Promoter methylation downregulates CDX2 expression in colorectal carcinomas. | Oncology reports 20050301 |
| Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia. | Anti-cancer drugs 20050301 |
| Aberrant methylation of Reprimo in lung cancer. | Lung cancer (Amsterdam, Netherlands) 20050301 |
| Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells. | Cancer research 20050301 |
| Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells. | Molecular cancer therapeutics 20050301 |
| Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. | Neoplasia (New York, N.Y.) 20050301 |
| Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma. | Neoplasia (New York, N.Y.) 20050301 |
| The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island. | Journal of biochemistry 20050301 |
| Structural and functional preservation of specific sequences of DNA and mRNA in apoptotic bodies from ES cells. | Apoptosis : an international journal on programmed cell death 20050301 |
| [5-Aza-2'-deoxycytidine enhances differentiation and apoptosis induced by phenylbutyrate in Kasumi-1 cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050301 |
| Therapeutic epigenetics: an emerging clinical approach to hematologic malignancies. | Clinical advances in hematology & oncology : H&O 20050301 |
| Effects of DNA methylation on galectin-3 expression in pituitary tumors. | Cancer research 20050215 |
| Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia. | Cancer research 20050215 |
| Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness. | International journal of cancer 20050210 |
| Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies. | International journal of cancer 20050210 |
| In vivo haematopoietic activity is induced in neurosphere cells by chromatin-modifying agents. | The EMBO journal 20050209 |
| Methylation-regulated expression of cancer testis antigens in primary effusion lymphoma: immunotherapeutic implications. | Journal of cellular physiology 20050201 |
| Oncogene regulation of tumor suppressor genes in tumorigenesis. | Carcinogenesis 20050201 |
| Silencing of the maternally imprinted tumor suppressor ARHI contributes to follicular thyroid carcinogenesis. | The Journal of clinical endocrinology and metabolism 20050201 |
| Epigenetic status and aberrant expression of the maspin gene in human hepato-biliary tract carcinomas. | Laboratory investigation; a journal of technical methods and pathology 20050201 |
| Reduced expression of human mismatch repair genes in adult T-cell leukemia. | American journal of hematology 20050201 |
| Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050201 |
| Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050201 |
| Silencing of the thrombomodulin gene in human malignant melanoma. | Melanoma research 20050201 |
| Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells. | The Journal of steroid biochemistry and molecular biology 20050201 |
| Activation of CMV promoter-controlled glycosyltransferase and beta -galactosidase glycogenes by butyrate, tricostatin A, and 5-aza-2'-deoxycytidine. | Glycoconjugate journal 20050201 |
| Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma. | Oncogene 20050127 |
| Restoration of expression of transforming growth factor-beta type II receptor in murine renal cell carcinoma (renca) cells by 5-Aza-2'-deoxycytidine. | Life sciences 20050121 |
| Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma. | International journal of cancer 20050120 |
| Characterization of {gamma}-aminobutyric acid type A receptor-associated protein, a novel tumor suppressor, showing reduced expression in breast cancer. | Cancer research 20050115 |
| Methylation of the gamma-catenin gene is associated with poor prognosis of renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050115 |
| Transcript profiling in Arabidopsis reveals complex responses to global inhibition of DNA methylation and histone deacetylation. | The Journal of biological chemistry 20050107 |
| Signaling properties and expression in normal and tumor tissues of two phospholipase C epsilon splice variants. | Oncogene 20050106 |
| Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway. | Oncogene 20050106 |
| Downregulation of connexin 26 in human lung cancer is related to promoter methylation. | International journal of cancer 20050101 |
| Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers. | International journal of cancer 20050101 |
| Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients. | Carcinogenesis 20050101 |
| Induction of gene expression by 5-Aza-2'-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and -independent mechanisms. | Leukemia 20050101 |
| Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing. | Investigative ophthalmology & visual science 20050101 |
| Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins. | Molecular cancer therapeutics 20050101 |
| Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma. | Neoplasia (New York, N.Y.) 20050101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20050101 |
| A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes. | BMC cancer 20050101 |
| Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain. | Cell transplantation 20050101 |
| Development and evaluation of a Gal4-mediated LUC/GFP/GUS enhancer trap system in Arabidopsis. | BMC plant biology 20050101 |
| Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study. | Molecular cancer 20050101 |
| Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes. | Journal of biomedicine & biotechnology 20050101 |
| Expression of S100P gene in cervical carcinoma cells is independent of E7 human papillomavirus oncogene. | Acta virologica 20050101 |
| X-inactivation status varies in human embryonic stem cell lines. | Stem cells (Dayton, Ohio) 20050101 |
| Epigenetic inactivation and aberrant transcription of CSMD1 in squamous cell carcinoma cell lines. | Cancer cell international 20050101 |
| Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms. | Retrovirology 20050101 |
| DNA mismatch repair deficiency, resistance to cancer chemotherapy and the development of hypersensitive agents. | Current topics in medicinal chemistry 20050101 |
| Epigenetics of cervical cancer. An overview and therapeutic perspectives. | Molecular cancer 20050101 |
| Downregulation of human kallikrein 10 (KLK10/NES1) by CpG island hypermethylation in breast, ovarian and prostate cancers. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20050101 |
| Update on supportive care and new therapies: immunomodulatory drugs, growth factors and epigenetic-acting agents. | Hematology. American Society of Hematology. Education Program 20050101 |
| Aberrant methylation of the CHFR gene in advanced hepatocellular carcinoma. | Hepato-gastroenterology 20050101 |
| Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation. | Molecular cancer 20050101 |
| XIST repression in the absence of DNMT1 and DNMT3B. | DNA research : an international journal for rapid publication of reports on genes and genomes 20050101 |
| [Epigenetic inactivation of the WNT antagonist SFRP1 in breast cancer]. | Verhandlungen der Deutschen Gesellschaft fur Pathologie 20050101 |
| Establishment of a detection system for demethylating agents using an endogenous promoter CpG island. | Mutation research 20041221 |
| Inactivation of the hMSH3 mismatch repair gene in bladder cancer. | Biochemical and biophysical research communications 20041217 |
| Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine. | Cancer research 20041215 |
| Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers. | British journal of cancer 20041213 |
| Epigenetic inactivation of RUNX3 in microsatellite unstable sporadic colon cancers. | International journal of cancer 20041210 |
| Regulation of Chk2 gene expression in lymphoid malignancies: involvement of epigenetic mechanisms in Hodgkin's lymphoma cell lines. | Cell death and differentiation 20041201 |
| Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells. | Human molecular genetics 20041201 |
| Nonclonal neutrophil responses after successful treatment of myelodysplasia with low-dose 5-aza-2'-deoxycytidine (decitabine). | Leukemia research 20041201 |
| Histone deacetylase inhibitors in myelodysplastic syndrome. | Best practice & research. Clinical haematology 20041201 |
| DNA methylation affects cell proliferation, cortisol secretion and steroidogenic gene expression in human adrenocortical NCI-H295R cells. | Journal of molecular endocrinology 20041201 |
| Decitabine. MGI Pharma Inc/SuperGen Inc. | IDrugs : the investigational drugs journal 20041201 |
| Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells. | Molecular cancer research : MCR 20041201 |
| Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells. | Cancer biology & therapy 20041201 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20041201 |
| Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines. | Cancer letters 20041125 |
| Fine mapping of the 11q22-23 tumor suppressive region and involvement of TSLC1 in nasopharyngeal carcinoma. | International journal of cancer 20041120 |
| Silencing the critics: new studies move closer to answering epigenetic questions. | Journal of the National Cancer Institute 20041117 |
| Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression. | Blood 20041115 |
| DNA methylation and cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041115 |
| Identification of 27 5' CpG islands aberrantly methylated and 13 genes silenced in human pancreatic cancers. | Oncogene 20041111 |
| Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality. | Oncology reports 20041101 |
| Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas. | Oncology reports 20041101 |
| Hypermethylation of growth arrest DNA damage-inducible gene 45 beta promoter in human hepatocellular carcinoma. | The American journal of pathology 20041101 |
| Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines. | Ai zheng = Aizheng = Chinese journal of cancer 20041101 |
| Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus. | Gene 20041027 |
| Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer. | International journal of cancer 20041020 |
| Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. | The Journal of clinical investigation 20041015 |
| The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041015 |
| Differential hypermethylation of SOCS genes in ovarian and breast carcinomas. | Oncogene 20041007 |
| Microarray analysis of gene regulation in the Hepa1c1c7 cell line following exposure to the DNA methylation inhibitor 5-aza-2'-deoxycytidine and 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Toxicology in vitro : an international journal published in association with BIBRA 20041001 |
| Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. | Cancer cell 20041001 |
| [Methylation of mismatch repair gene (MMR) in primary hepatocellular carcinoma]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20041001 |
| The molecular mechanism of fetal hemoglobin reactivation. | Seminars in hematology 20041001 |
| Clinical studies with fetal hemoglobin-enhancing agents in sickle cell disease. | Seminars in hematology 20041001 |
| The role of fetal hemoglobin-enhancing agents in thalassemia. | Seminars in hematology 20041001 |
| Issues regarding study design for initial clinical trials using decitabine. | Seminars in hematology 20041001 |
| Frequent downregulation of 14-3-3 sigma protein and hypermethylation of 14-3-3 sigma gene in salivary gland adenoid cystic carcinoma. | British journal of cancer 20040913 |
| 5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells. | Oncogene 20040902 |
| Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines. | Oncogene 20040902 |
| Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells. | American journal of physiology. Gastrointestinal and liver physiology 20040901 |
| Demethylating agent 5-aza-2'-deoxycytidine enhances expression of TNFRI and promotes TNF-mediated apoptosis in vitro and in vivo. | Oncology reports 20040901 |
| Enhanced sensitivity of prostate cancer DU145 cells to cisplatinum by 5-aza-2'-deoxycytidine. | Oncology reports 20040901 |
| Prevalent hyper-methylation of the CDH13 gene promoter in malignant B cell lymphomas. | International journal of oncology 20040901 |
| DNA hypo-methylating agents and sickle cell disease. | British journal of haematology 20040901 |
| CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancer. | Cancer research 20040901 |
| Identification of aberrantly methylated genes in association with adult T-cell leukemia. | Cancer research 20040901 |
| Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040901 |
| Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers. | Cancer science 20040901 |
| DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon. | Cancer letters 20040830 |
| CpG methylation of the mouse CYP1A2 promoter. | Toxicology letters 20040830 |
| Role of IFI 16 in cellular senescence of human fibroblasts. | Oncogene 20040819 |
| Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. | The Journal of biological chemistry 20040813 |
| The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma. | Cancer immunity 20040809 |
| Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells. | Laboratory investigation; a journal of technical methods and pathology 20040801 |
| Myelodysplasia, megakaryocytes, and methylation. | Leukemia research 20040801 |
| The effects of 5-aza-2'-deoxycytidine (Decitabine) on the platelet count in patients with intermediate and high-risk myelodysplastic syndromes. | Leukemia research 20040801 |
| Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development. | Gut 20040801 |
| Influence of CpG island methylation status in O6-methylguanine-DNA methyltransferase expression of oral cancer cell lines. | Oncology reports 20040801 |
| Demethylation of DNA by decitabine in cancer chemotherapy. | Expert review of anticancer therapy 20040801 |
| Apoptotic speck protein-like, a highly homologous protein to apoptotic speck protein in the pyrin domain, is silenced by DNA methylation and induces apoptosis in human hepatocellular carcinoma. | Cancer research 20040801 |
| Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer. | Cancer research 20040801 |
| Down-regulation and promoter methylation of tissue inhibitor of metalloproteinase 3 in choriocarcinoma. | Gynecologic oncology 20040801 |
| [Effect of 5-aza-2'-deoxycytidine on cell of high-risk patients with myelodysplastic syndrome in vitro]. | Zhongguo shi yan xue ye xue za zhi 20040801 |
| DNA methylation as a therapeutic target in hematologic disorders: recent results in older patients with myelodysplasia and acute myeloid leukemia. | International journal of hematology 20040801 |
| [Growth and gene expression of leukemia cell after treated with methylation inhibitor 5-aza-2'-deoxycytidine]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040801 |
| Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells. | British journal of cancer 20040719 |
| Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer. | Cancer research 20040715 |
| HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells. | Cancer research 20040715 |
| Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3. | The Journal of biological chemistry 20040702 |
| 14-3-3sigma is down-regulated in human prostate cancer. | Biochemical and biophysical research communications 20040702 |
| Effects of demethylating agent 5-aza-2(')-deoxycytidine and histone deacetylase inhibitor FR901228 on maspin gene expression in oral cancer cell lines. | Oral oncology 20040701 |
| MEIS 1 expression is downregulated through promoter hypermethylation in AML1-ETO acute myeloid leukemias. | Leukemia 20040701 |
| Less frequent promoter hypermethylation of DLC-1 gene in primary breast cancers. | Oncology reports 20040701 |
| Methylation-associated silencing of the heat shock protein 47 gene in human neuroblastoma. | Cancer research 20040701 |
| Frequent promoter methylation and gene silencing of CDH13 in pancreatic cancer. | Cancer science 20040701 |
| Aberrant gene expression in human non small cell lung carcinoma cells exposed to demethylating agent 5-aza-2'-deoxycytidine. | Neoplasia (New York, N.Y.) 20040701 |
| Epigenetic modifications affect Dnmt3L expression. | The Biochemical journal 20040615 |
| Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma. | International journal of cancer 20040610 |
| The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma. | Oncogene 20040610 |
| Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells. | FEBS letters 20040604 |
| Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A. | Blood 20040601 |
| MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine. | Cancer biology & therapy 20040601 |
| Antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and depsipeptide on Raji lymphoma cells. | Oncology reports 20040601 |
| Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma. | Cancer research 20040601 |
| Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens. | Cancer research 20040601 |
| The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies. | The Journal of clinical investigation 20040601 |
| Epigenetic modification regulates both expression of tumor-associated genes and cell cycle progressing in human colon cancer cell lines: Colo-320 and SW1116. | Cell research 20040601 |
| Epigenetic regulation of MDR1 gene in breast cancer: CpG methylation status dominates the stable maintenance of a silent gene. | Cancer biology & therapy 20040601 |
| Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling. | Carcinogenesis 20040501 |
| Homozygous deletion and expression of PTEN and DMBT1 in human primary neuroblastoma and cell lines. | International journal of cancer 20040501 |
| Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types. | International journal of cancer 20040501 |
| DNA methylation profiles of lymphoid and hematopoietic malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040501 |
| Gamma-catenin expression is reduced or absent in a subset of human non-small cell lung cancers, and its re-expression inhibits cell growth. | Chest 20040501 |
| Hypermethylation of the PTEN gene in ovarian cancer cell lines. | Cancer letters 20040430 |
| Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. | The Journal of biological chemistry 20040423 |
| Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions. | Oncogene 20040422 |
| Methylation analysis of the glypican 3 gene in embryonal tumours. | British journal of cancer 20040419 |
| Expression and methylation status of 14-3-3 sigma gene can characterize the different histological features of ovarian cancer. | Biochemical and biophysical research communications 20040416 |
| Cancer chemotherapy targeted at reactivating the expression of epigenetically inactivated genes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415 |
| Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor. | Cancer research 20040415 |
| Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas. | International journal of cancer 20040410 |
| 5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation. | The Journal of biological chemistry 20040409 |
| Carcinogen exposure differentially modulates RAR-beta promoter hypermethylation, an early and frequent event in mouse lung carcinogenesis. | Carcinogenesis 20040401 |
| Increase in DNA methylation downregulates conceptus interferon-tau gene expression. | Molecular reproduction and development 20040401 |
| Human PinX1, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma. | Oncology reports 20040401 |
| Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers. | Cancer research 20040401 |
| Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets. | Cancer research 20040401 |
| Demethylation of the synuclein gamma gene CpG island in primary gastric cancers and gastric cancer cell lines. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040401 |
| The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040401 |
| Targeted therapies in myelodysplastic syndromes: ASH 2003 review. | Seminars in hematology 20040401 |
| Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas. | Journal of the National Cancer Institute 20040317 |
| Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia. | Cancer research 20040315 |
| Downregulation of retinoic acid receptor-beta(2) expression is linked to aberrant methylation in esophageal squamous cell carcinoma cell lines. | World journal of gastroenterology 20040315 |
| Epigenetic inactivation of TMS1/ASC in ovarian cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040315 |
| Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040315 |
| Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells. | Oncogene 20040304 |
| Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. | Blood 20040301 |
| Hypermethylation of retrotransposons in the liverwort Marchantia paleacea var. diptera. | Plant cell reports 20040301 |
| Frequent hypermethylation of 5' flanking region of TIMP-2 gene in cervical cancer. | International journal of cancer 20040301 |
| DNA methylation as an epigenetic regulator of neural 5-lipoxygenase expression: evidence in human NT2 and NT2-N cells. | Journal of neurochemistry 20040301 |
| Genomic surgery for lung cancer. | The Journal of surgical research 20040301 |
| Hypermethylation of the retinoic acid receptor-beta(2) gene in head and neck carcinogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040301 |
| Transplacental exposure to the DNA demethylating agent, 5-AZA-CdR, affects the sexual behavior of CD-1 male mice. | Neurotoxicology 20040301 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20040301 |
| Aberrant expression of the maspin gene associated with epigenetic modification in melanoma cells. | The Journal of investigative dermatology 20040301 |
| Methylation of a CpG island within the uroplakin Ib promoter: a possible mechanism for loss of uroplakin Ib expression in bladder carcinoma. | Neoplasia (New York, N.Y.) 20040301 |
| DLC-1 operates as a tumor suppressor gene in human non-small cell lung carcinomas. | Oncogene 20040219 |
| [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines]. | Zhonghua yi xue za zhi 20040217 |
| 5-Aza-2'-deoxycytidine stimulates inducible nitric oxide synthase induction in C6 astrocytoma cells. | Brain research 20040213 |
| Frequent epigenetic inactivation of the RASSF1A tumor suppressor gene in Hodgkin's lymphoma. | Oncogene 20040212 |
| 5-Aza-2'-deoxycytidine and paclitaxel inhibit inducible nitric oxide synthase activation in fibrosarcoma cells. | European journal of pharmacology 20040206 |
| Disruption of cell-type-specific methylation at the Maspin gene promoter is frequently involved in undifferentiated thyroid cancers. | Oncogene 20040205 |
| Ubiquitous aberrant RASSF1A promoter methylation in childhood neoplasia. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040201 |
| Dual repair modulation reverses Temozolomide resistance in vitro. | Molecular cancer therapeutics 20040201 |
| [Effect of inhibitors for demethylation and histone deacetylase on proliferation of cell line K562 and expression of tumor related genes]. | Zhongguo shi yan xue ye xue za zhi 20040201 |
| Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines. | Anti-cancer drugs 20040201 |
| Loss of expression of the growth inhibitory gene GADD45gamma, in human pituitary adenomas, is associated with CpG island methylation. | Oncogene 20040129 |
| The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine. | Oncogene 20040122 |
| Expression and regulation of tumor suppressor gene maspin in human bladder cancer. | Cancer letters 20040120 |
| PMP24, a gene identified by MSRF, undergoes DNA hypermethylation-associated gene silencing during cancer progression in an LNCaP model. | Oncogene 20040108 |
| Mutation of CpGs in the murine stem cell virus retroviral vector long terminal repeat represses silencing in embryonic stem cells. | The Journal of biological chemistry 20040102 |
| In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines. | Blood 20040101 |
| Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines. | Molecular carcinogenesis 20040101 |
| CHFR-associated early G2/M checkpoint defects in breast cancer cells. | Molecular carcinogenesis 20040101 |
| hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling. | Gastroenterology 20040101 |
| Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine. | Molecular pharmacology 20040101 |
| Methylation and regulation of expression of different retinoic acid receptor beta isoforms in human colon cancer. | Cancer biology & therapy 20040101 |
| 5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of p16INK4A gene in human gastric cancer cell lines. | Chinese medical journal 20040101 |
| Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation. | Molecular cancer research : MCR 20040101 |
| Activation of expression of p15, p73 and E-cadherin in leukemic cells by different concentrations of 5-aza-2'-deoxycytidine (Decitabine). | Anticancer research 20040101 |
| Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by phenylbutyrate on L1210 leukemic cells. | Leukemia & lymphoma 20040101 |
| 5-aza-2'-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis. | Clinical & experimental metastasis 20040101 |
| Absence of annexin I expression in B-cell non-Hodgkin's lymphomas and cell lines. | BMC cancer 20040101 |
| Role of epigenetic DNA alterations in the pathogenesis of systemic lupus erythematosus. | Journal of applied genetics 20040101 |
| Role of promoter hypermethylation in Cisplatin treatment response of male germ cell tumors. | Molecular cancer 20040101 |
| Formation of mitoxantrone adducts in human tumor cells: potentiation by AN-9 and DNA methylation. | Oncology research 20040101 |
| Promoter methylation regulates cyclooxygenase expression in breast cancer. | Breast cancer research : BCR 20040101 |
| Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites. | Breast cancer research : BCR 20040101 |
| Aberrant CBFA2T3B gene promoter methylation in breast tumors. | Molecular cancer 20040101 |
| Aberrant methylation and histone deacetylation associated with silencing of SLC5A8 in gastric cancer. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20040101 |
| Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. | BMC cancer 20040101 |
| New nucleoside analogs in the treatment of hematological disorders. | Acta poloniae pharmaceutica 20040101 |
| Sickle cell disease. | Hematology. American Society of Hematology. Education Program 20040101 |
| CpG methylation of the FHIT, FANCF, cyclin-D2, BRCA2 and RUNX3 genes in Granulosa cell tumors (GCTs) of ovarian origin. | Molecular cancer 20040101 |
| New nucleoside analogs in the treatment of solid tumors. | Acta poloniae pharmaceutica 20040101 |
| The role of methyltransferase inhibitors in the management of the myelodysplastic syndromes. | Cancer control : journal of the Moffitt Cancer Center 20040101 |
| Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine. | Clinical & experimental metastasis 20040101 |
| Approaches to the reactivation of hemoglobin F as a treatment for sickle cell disease. | Clinical advances in hematology & oncology : H&O 20040101 |
| Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice. | Oncogene 20031218 |
| Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031215 |
| Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer. | Cancer research 20031215 |
| Hepatocyte growth factor activator inhibitor 2/placental bikunin (HAI-2/PB) gene is frequently hypermethylated in human hepatocellular carcinoma. | Cancer research 20031215 |
| [The study of 5-Aza-2'-deoxycytidine on transcription regulation of p16/CDKN2 gene demethylation in RKO human colorectal cell line]. | Zhonghua yi xue za zhi 20031210 |
| Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer. | Cancer letters 20031208 |
| Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation. | Oncogene 20031204 |
| The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor. | American journal of respiratory cell and molecular biology 20031201 |
| Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease. | Blood 20031201 |
| The histone code regulating expression of the imprinted mouse Igf2r gene. | Endocrinology 20031201 |
| Promoter methylation of cyclin D2 gene in gastric carcinoma. | International journal of oncology 20031201 |
| Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma. | Molecular carcinogenesis 20031201 |
| DNA methylation in haematological malignancies: the role of decitabine. | Expert opinion on investigational drugs 20031201 |
| DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor. | Hepatology (Baltimore, Md.) 20031201 |
| Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine. | Electrophoresis 20031201 |
| Activated proliferation of B-cell lymphomas/leukemias with the SHP1 gene silencing by aberrant CpG methylation. | Laboratory investigation; a journal of technical methods and pathology 20031201 |
| [DNA methylation and cancer--DNA methylation as a target of cancer chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031201 |
| Decitabine: development of a DNA methyltransferase inhibitor for hematological malignancies. | Current opinion in investigational drugs (London, England : 2000) 20031201 |
| Demethylation of host-cell DNA at the site of avian retrovirus integration. | Biochemical and biophysical research communications 20031121 |
| Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV). | International journal of cancer 20031120 |
| Genetic and epigenetic alterations of DLC-1 gene in hepatocellular carcinoma. | Cancer research 20031115 |
| Restoration of insulin-like growth factor binding protein-related protein 1 has a tumor-suppressive activity through induction of apoptosis in human prostate cancer. | Cancer research 20031115 |
| Comment on 'Chromosomal instability and tumors promoted by DNA hypomethylation' and 'Induction of tumors in nice by genomic hypomethylation'. | Science (New York, N.Y.) 20031114 |
| Silencing of CDX2 expression in colon cancer via a dominant repression pathway. | The Journal of biological chemistry 20031107 |
| Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway. | Leukemia research 20031101 |
| ASC/TMS1, a caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma. | International journal of cancer 20031101 |
| Cell-type-specific repression of the maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells. | The American journal of pathology 20031101 |
| Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. | Cancer research 20031101 |
| Decitabine. | Current opinion in oncology 20031101 |
| Epigenetic silencing of the HIC-1 gene in human medulloblastomas. | Journal of neuropathology and experimental neurology 20031101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20031101 |
| Role of promoter methylation in regulation of the mammalian heparanase gene. | Oncogene 20031030 |
| Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors. | Oncogene 20031030 |
| Hypermethylation of the hTERT promoter inhibits the expression of telomerase activity in normal oral fibroblasts and senescent normal oral keratinocytes. | British journal of cancer 20031020 |
| Strategies for reversing drug resistance. | Oncogene 20031020 |
| Transcriptional regulation of mouse delta-opioid receptor gene by CpG methylation: involvement of Sp3 and a methyl-CpG-binding protein, MBD2, in transcriptional repression of mouse delta-opioid receptor gene in Neuro2A cells. | The Journal of biological chemistry 20031017 |
| Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells. | Oncogene 20031016 |
| Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. | Oncogene 20031009 |
| Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres. | Experimental cell research 20031001 |
| Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma. | The American journal of pathology 20031001 |
| Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model. | The Journal of pathology 20031001 |
| Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma. | Cancer research 20031001 |
| Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS. | Clinical immunology (Orlando, Fla.) 20031001 |
| A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. | Breast cancer research and treatment 20031001 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20031001 |
| Novel biospecific agents for the treatment of myelodysplastic syndromes. | Journal of the National Comprehensive Cancer Network : JNCCN 20031001 |
| Cancer epigenetics. | Oncogene 20030929 |
| Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells. | The Journal of biological chemistry 20030926 |
| Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas. | Cancer letters 20030925 |
| Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation. | The Journal of biological chemistry 20030919 |
| Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines. | World journal of gastroenterology 20030915 |
| Expression profiling reveals that methylation of TIMP3 is involved in uveal melanoma development. | International journal of cancer 20030910 |
| Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine. | Biology of reproduction 20030901 |
| Mutations and aberrant DNA methylation of the PROX1 gene in hematologic malignancies. | Genes, chromosomes & cancer 20030901 |
| Epigenetic inactivation of RASSF1A in head and neck cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030901 |
| Differential expression of bikunin (HAI-2/PB), a proposed mediator of glioma invasion, by demethylation treatment. | Journal of neuro-oncology 20030901 |
| Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control. | Neoplasia (New York, N.Y.) 20030901 |
| Aberrant methylation of TMS1 in small cell, non small cell lung cancer and breast cancer. | International journal of cancer 20030820 |
| Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. | Cancer research 20030815 |
| Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030815 |
| Molecular cloning and characterization of human acid sensing ion channel (ASIC)2 gene promoter. | Gene 20030814 |
| Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma. | International journal of cancer 20030810 |
| Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines. | International journal of cancer 20030810 |
| Down-regulation of FEZ1/LZTS1 gene with frequent loss of heterozygosity in oral squamous cell carcinomas. | International journal of oncology 20030801 |
| Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia. | Cancer 20030801 |
| Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers. | Cancer research 20030801 |
| Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis. | Cancer research 20030801 |
| Epigenetic down-regulation of death-associated protein kinase in lung cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
| Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
| Enrichment for histone H3 lysine 9 methylation at Alu repeats in human cells. | The Journal of biological chemistry 20030725 |
| Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms. | British journal of cancer 20030721 |
| Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma. | Biochemical and biophysical research communications 20030718 |
| Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells. | Oncogene 20030717 |
| Frequent epigenetic inactivation of the SLIT2 gene in gliomas. | Oncogene 20030717 |
| Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression. | Cancer research 20030715 |
| Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma. | Cancer research 20030715 |
| Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers. | Cancer research 20030715 |
| Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos. | Biology of reproduction 20030701 |
| Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays. | Cancer research 20030701 |
| Epigenetic inactivation of laminin-5-encoding genes in lung cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030701 |
| Restoration of silenced Peutz-Jeghers syndrome gene, LKB1, induces apoptosis in pancreatic carcinoma cells. | Neoplasia (New York, N.Y.) 20030701 |
| Epigenetic silencing of multiple interferon pathway genes after cellular immortalization. | Oncogene 20030626 |
| Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia. | International journal of cancer 20030620 |
| Methylation-regulated expression of HLA class I antigens in melanoma. | International journal of cancer 20030620 |
| Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells. | Oncogene 20030619 |
| Multiple promoters of catechol-O-methyltransferase gene are selectively inactivated by CpG hypermethylation in endometrial cancer. | Cancer research 20030615 |
| Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma. | Oncogene 20030612 |
| Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression. | Oncogene 20030605 |
| Over-expression of DNA methyltransferases and CDKN2A gene methylation status in squamous cell carcinoma of the oral cavity. | International journal of oncology 20030601 |
| Absence of hamTERT gene expression is associated with promoter hypermethylation in immortal hamster buccal pouch epithelial cells. | International journal of oncology 20030601 |
| 5-Aza-2'-deoxycytidine (decitabine) treatment of hematopoietic malignancies: a multimechanism therapeutic approach? | Blood 20030601 |
| DNA mismatch repair genes in renal cell carcinoma. | The Journal of urology 20030601 |
| The human T-cell factor-4 gene splicing isoforms, Wnt signal pathway, and apoptosis in renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030601 |
| Epigenetic regulation of proprotein convertase PACE4 gene expression in human ovarian cancer cells. | Molecular cancer research : MCR 20030601 |
| Aberrant methylation of the vascular endothelial growth factor receptor-1 gene in prostate cancer. | Cancer science 20030601 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20030601 |
| Changes in zinc, copper and metallothionein contents during oocyte growth and early development of the teleost Danio rerio (zebrafish). | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030601 |
| Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter. | The Journal of biological chemistry 20030530 |
| MAL gene expression in esophageal cancer suppresses motility, invasion and tumorigenicity and enhances apoptosis through the Fas pathway. | Oncogene 20030529 |
| Effects of methylation on expression of TMS1/ASC in human breast cancer cells. | Oncogene 20030529 |
| Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer. | British journal of cancer 20030519 |
| Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. | Blood 20030515 |
| Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma. | International journal of cancer 20030510 |
| Susceptibility to postnatal growth retardation induced by 5-AZA-2'-deoxycytidine in utero: gender specificity and correlation with reduced insulin-like growth factor 1. | Life sciences 20030509 |
| Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells. | Leukemia research 20030501 |
| Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines. | Leukemia research 20030501 |
| Promoter hypermethylation of cyclooxygenase-2 in gastric carcinoma. | International journal of oncology 20030501 |
| Cytosine methylation occurs in a CDC48 homologue and a MADS-box gene during adventitious shoot induction in Petunia leaf explants. | Journal of experimental botany 20030501 |
| Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation. | Cancer research 20030501 |
| Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030501 |
| The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells. | Current medicinal chemistry. Anti-cancer agents 20030501 |
| Hypermethylation can selectively silence multiple promoters of steroid receptors in cancers. | Molecular and cellular endocrinology 20030428 |
| Epigenomic stress response. Knockdown of DNA methyltransferase 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes. | The Journal of biological chemistry 20030425 |
| Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia. | Oncogene 20030424 |
| JunB gene expression is inactivated by methylation in chronic myeloid leukemia. | Blood 20030415 |
| DNA hypermethylation near the transcription start site of collagen alpha2(I) gene occurs in both cancer cell lines and primary colorectal cancers. | Cancer research 20030415 |
| SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma. | Blood 20030401 |
| Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16INK4A/pRb. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401 |
| Upregulation of galectin-7 in murine lymphoma cells is associated with progression toward an aggressive phenotype. | Leukemia 20030401 |
| Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030401 |
| Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples. | The Journal of clinical investigation 20030315 |
| Inhibition of DNA methylation and reactivation of silenced genes by zebularine. | Journal of the National Cancer Institute 20030305 |
| Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias. | Cancer 20030301 |
| A systematic profile of DNA methylation in human cancer cell lines. | Cancer research 20030301 |
| Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinsing fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patient. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030301 |
| Interaction of 5-aza-2'-deoxycytidine and depsipeptide on antineoplastic activity and activation of 14-3-3sigma, E-cadherin and tissue inhibitor of metalloproteinase 3 expression in human breast carcinoma cells. | Anti-cancer drugs 20030301 |
| Phase I trial of continuous infusion 5-aza-2'-deoxycytidine. | Cancer chemotherapy and pharmacology 20030301 |
| E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours. | European journal of cancer (Oxford, England : 1990) 20030301 |
| Therapies to increase fetal hemoglobin in sickle cell disease. | Current hematology reports 20030301 |
| Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness. | Journal of the National Cancer Institute 20030219 |
| On the use of DNA methylation inhibitors and the reversal of transcriptional silencing. | Blood 20030215 |
| Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma. | Genes, chromosomes & cancer 20030201 |
| Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells. | International journal of oncology 20030201 |
| Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma. | Cancer research 20030201 |
| Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells. | Leukemia 20030201 |
| Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma. | Cell death and differentiation 20030201 |
| Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia. | Oncogene 20030123 |
| Methylation-associated silencing of heparan sulfate D-glucosaminyl 3-O-sulfotransferase-2 (3-OST-2) in human breast, colon, lung and pancreatic cancers. | Oncogene 20030116 |
| Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers. | Cancer genetics and cytogenetics 20030115 |
| Synergistic antineoplastic action of DNA methylation inhibitor 5-AZA-2'-deoxycytidine and histone deacetylase inhibitor depsipeptide on human breast carcinoma cells. | International journal of cancer 20030110 |
| DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. | Nature genetics 20030101 |
| Frequent hypermethylation of the 5' CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer. | Carcinogenesis 20030101 |
| Advanced-phase chronic myeloid leukemia. | Seminars in hematology 20030101 |
| 5-AZA-2'-deoxycytidine (5-AZA-CdR): a demethylating agent affecting development and reproductive capacity. | Journal of applied toxicology : JAT 20030101 |
| Down-regulation of connexin 32 gene expression through DNA methylation in a human renal cell carcinoma cell. | American journal of nephrology 20030101 |
| An epigenetic approach for finding tumor suppressors. | Cell cycle (Georgetown, Tex.) 20030101 |
| Hypermethylation of death-associated protein (DAP) kinase CpG island is frequent not only in B-cell but also in T- and natural killer (NK)/T-cell malignancies. | Cancer science 20030101 |
| Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716. | Drugs in R&D 20030101 |
| Reduced expression of GNA11 and silencing of MCT1 in human breast cancers. | Oncology 20030101 |
| Frequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: its relationship to clinical outcome. | Molecular cancer 20030101 |
| Inactivation of the RASSF1A in osteosarcoma. | Oncology reports 20030101 |
| 5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome. | Journal of andrology 20030101 |
| Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716. | Drugs in R&D 20030101 |
| The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses. | BMC cancer 20030101 |
| Expression of biomarkers modulating prostate cancer angiogenesis: differential expression of annexin II in prostate carcinomas from India and USA. | Molecular cancer 20030101 |
| Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines. | Cancer biology & therapy 20030101 |
| Induction of the estrogen receptor by ablation of DNMT1 in ER-negative breast cancer cells. | Cancer biology & therapy 20030101 |
| Hemoglobinopathies. | Hematology. American Society of Hematology. Education Program 20030101 |
| Possible role of DNA hypomethylation in the induction of SLE: relationship to the transcription of human endogenous retroviruses. | Clinical and experimental rheumatology 20030101 |
| Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. | Cancer research 20021215 |
| ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase. | Cell 20021213 |
| An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin. | Nature genetics 20021201 |
| Induction of TRAG-3 expression in A549 lung adenocarcinoma cell line by 5-aza-2' deoxyazacytidine. | Lung cancer (Amsterdam, Netherlands) 20021201 |
| Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma. | Cancer research 20021201 |
| Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20021201 |
| Evidence- and consensus-based practice guidelines for the therapy of primary myelodysplastic syndromes. A statement from the Italian Society of Hematology. | Haematologica 20021201 |
| DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias. | Haematologica 20021201 |
| Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. | Cancer cell 20021201 |
| Decitabine has promising clinical activity in chronic myeloid leukemia. | Expert review of anticancer therapy 20021201 |
| The human telomerase RNA gene (hTERC) is regulated during carcinogenesis but is not dependent on DNA methylation. | Carcinogenesis 20021201 |
| [Myelodysplastic syndromes. Diagnosis and therapeutic strategies]. | Medizinische Klinik (Munich, Germany : 1983) 20021115 |
| Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine. | Cancer research 20021115 |
| Identification of silencing of nine genes in human gastric cancers. | Cancer research 20021115 |
| A novel gene, FAM11A, associated with the FRAXF CpG island is transcriptionally silent in FRAXF full mutation. | European journal of human genetics : EJHG 20021101 |
| Electrophoretic variant of a lactate dehydrogenase isoenzyme and selective promoter methylation of the LDHA gene in a human retinoblastoma cell line. | Clinical chemistry 20021101 |
| DNA methyltransferase inhibitors-state of the art. | Annals of oncology : official journal of the European Society for Medical Oncology 20021101 |
| Re-expression of p16 gene in the myeloma cell line U266 induced by synergy of sodium butyrate and 5-Aza-2'-deoxycytidine. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021101 |
| [The re-expression of p15(INK4B) gene in leukemia cells induced by in vitro DNA methyltransferase and histone deacetylase inhibition]. | Zhonghua nei ke za zhi 20021101 |
| [The roles of DNA methylation in human neoplasms]. | Ai zheng = Aizheng = Chinese journal of cancer 20021101 |
| gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth. | Oncogene 20021024 |
| Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. | Blood 20021015 |
| Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells. | Journal of immunology (Baltimore, Md. : 1950) 20021015 |
| Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. | Cancer research 20021015 |
| Hypermethylation-associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer. | Cancer research 20021015 |
| Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development. | Cancer research 20021015 |
| Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells. | The Journal of biological chemistry 20021011 |
| Inhibition of HhaI DNA (Cytosine-C5) methyltransferase by oligodeoxyribonucleotides containing 5-aza-2'-deoxycytidine: examination of the intertwined roles of co-factor, target, transition state structure and enzyme conformation. | Journal of molecular biology 20021011 |
| Frequent hypermethylation of the RASSF1A gene in prostate cancer. | Oncogene 20021003 |
| Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome. | American journal of human genetics 20021001 |
| Aberrant DNA methylation of p57(KIP2) gene in the promoter region in lymphoid malignancies of B-cell phenotype. | Blood 20021001 |
| Seeking a way to alleviate sickle cell disease. | JAMA 20021001 |
| Phase II trial of cisplatin plus decitabine, a new DNA hypomethylating agent, in patients with advanced squamous cell carcinoma of the cervix. | American journal of clinical oncology 20021001 |
| [Apoptosis and re-expression of p16 gene in the myeloma cell line U266 induced by synergy of histone deacetylase inhibitor and demethylating agent]. | Ai zheng = Aizheng = Chinese journal of cancer 20021001 |
| DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines. | The Journal of biological chemistry 20020927 |
| Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. | Cancer letters 20020926 |
| Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. | Circulation research 20020920 |
| New drugs in acute myeloid leukemia. | Current oncology reports 20020901 |
| Antineoplastic action of 5-aza-2'-deoxycytidine and phenylbutyrate on human lung carcinoma cells. | Anti-cancer drugs 20020901 |
| Zebularine: a novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases. | Journal of molecular biology 20020823 |
| 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. | Oncogene 20020812 |
| Reactivating the expression of methylation silenced genes in human cancer. | Oncogene 20020812 |
| 5-aza-2'-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: immunotherapeutic implications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020801 |
| Role of DNA methylation in transcription of human endogenous retrovirus in the pathogenesis of systemic lupus erythematosus. | The Journal of rheumatology 20020801 |
| CpG hypermethylation of promoter region and inactivation of E-cadherin gene in human bladder cancer. | Molecular carcinogenesis 20020801 |
| [Inhibitory effect on proliferation of KG1a cell line by methyltransferase inhibitors]. | Zhongguo shi yan xue ye xue za zhi 20020801 |
| Loss of retinoic acid receptor beta gene expression is linked to aberrant histone H3 acetylation in lung cancer cell lines. | Cancer research 20020715 |
| Methylation of adenomatous polyposis coli in endometrial cancer occurs more frequently in tumors with microsatellite instability phenotype. | Cancer research 20020701 |
| Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma. | Cancer research 20020701 |
| Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020701 |
| Reduced expression of the insulin-induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers. | International journal of cancer 20020701 |
| SNPs in the CpG island of NAP1L2: a possible link between DNA methylation and neural tube defects? | American journal of medical genetics 20020701 |
| Myelodysplastic syndrome overview. | Seminars in hematology 20020701 |
| Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells. | The Journal of biological chemistry 20020621 |
| Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. | Oncogene 20020620 |
| Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers. | British journal of cancer 20020617 |
| Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas. | Cancer research 20020615 |
| DNA hypomethylating agents 5-aza-2'-deoxycytidine and valproate increase neuronal 5-lipoxygenase mRNA. | European journal of pharmacology 20020607 |
| DNA methylation in the androgen receptor gene promoter region in rat prostate cancers. | The Prostate 20020601 |
| Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia. | Blood 20020601 |
| DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines. | Molecular immunology 20020601 |
| Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids. | Plant physiology 20020601 |
| Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene. | Biochemical and biophysical research communications 20020524 |
| In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer. | British journal of cancer 20020520 |
| Regulation of ALF gene expression in somatic and male germ line tissues involves partial and site-specific patterns of methylation. | The Journal of biological chemistry 20020517 |
| Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers. | Oncogene 20020502 |
| Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020501 |
| Hypertonicity induction of melanoma antigen, a tumor-associated antigen. | Molecules and cells 20020430 |
| Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors. | Oncogene 20020418 |
| Cell division is required for de novo methylation of CpG islands in bladder cancer cells. | Cancer research 20020415 |
| Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers. | Oncogene 20020404 |
| Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer. | Cancer research 20020401 |
| Differentiation therapy for myelodysplastic syndrome. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020401 |
| Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020401 |
| 5-Aza-2'-deoxycytidine-induced cytotoxicity and limb reduction defects in the mouse. | Teratology 20020401 |
| Hypermethylation of the imprinted NNAT locus occurs frequently in pediatric acute leukemia. | Carcinogenesis 20020401 |
| Current therapy of chronic myelogenous leukemia. | Internal medicine (Tokyo, Japan) 20020401 |
| Review of the clinical experience with 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumors. | Current opinion in investigational drugs (London, England : 2000) 20020401 |
| Cancer testis antigens expression in mesothelioma: role of DNA methylation and bioimmunotherapeutic implications. | British journal of cancer 20020318 |
| In vivo repression of an erythroid-specific gene by distinct corepressor complexes. | The EMBO journal 20020315 |
| p16INK4a loss and sensitivity in KSHV associated primary effusion lymphoma. | Oncogene 20020314 |
| Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate cancer. | Journal of the National Cancer Institute 20020306 |
| Combined restriction landmark genomic scanning and virtual genome scans identify a novel human homeobox gene, ALX3, that is hypermethylated in neuroblastoma. | Genes, chromosomes & cancer 20020301 |
| Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors. | The Journal of clinical endocrinology and metabolism 20020301 |
| High prevalence of decreased expression of KAI1 metastasis suppressor in human oral carcinogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020301 |
| Complex relationships between 5-aza-dC induced DNA demethylation and chromosome compaction at mitosis. | Chromosoma 20020301 |
| Reduced expression of insulin-like growth factor binding protein-3 and its promoter hypermethylation in human hepatocellular carcinoma. | Cancer letters 20020225 |
| Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture. | The Journal of biological chemistry 20020215 |
| Somatic recombination: a major genotoxic effect of two pyrimidine antimetabolitic chemotherapeutic drugs in Drosophila melanogaster. | Mutation research 20020215 |
| Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine. | Cancer research 20020215 |
| The 5-lipoxygenase promoter is regulated by DNA methylation. | The Journal of biological chemistry 20020208 |
| Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. | Science (New York, N.Y.) 20020208 |
| Frequent allelic losses on the short arm of chromosome 1 and decreased expression of the p73 gene at 1p36.3 in squamous cell carcinoma of the oral cavity. | International journal of oncology 20020201 |
| Lack of a consistent relationship between demethylation of the CD44 promoter and CD44 expression. | Immunogenetics 20020201 |
| Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer. | Carcinogenesis 20020201 |
| Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1. | British journal of cancer 20020121 |
| Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. | International journal of cancer 20020120 |
| Characterization of XAGE-1b, a short major transcript of cancer/testis-associated gene XAGE-1, induced in melanoma metastasis. | International journal of cancer 20020110 |
| Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells. | Gene 20020109 |
| DNA methylation regulates the expression of Y chromosome specific genes in prostate cancer. | The Journal of urology 20020101 |
| Novel agents for the therapy of acute leukemia. | Current opinion in oncology 20020101 |
| De novo expression of the Muc2 gene in pancreas carcinoma cells is triggered by promoter demethylation. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20020101 |
| Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20020101 |
| Methylation and silencing of the retinoic acid receptor-beta 2 gene in cervical cancer. | BMC cancer 20020101 |
| 93rd Annual Meeting of the American Association for Cancer Research, San Francisco, CA, USA, 6-10 April 2002. | Breast cancer research : BCR 20020101 |
| Expression spectrum and methylation-dependent regulation of melanoma antigen-encoding gene family members in pancreatic cancer cells. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20020101 |
| Methylation state of the prostate specific membrane antigen (PSMA) CpG island in prostate cancer cell lines. | Anticancer research 20020101 |
| MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas. | Journal of human genetics 20020101 |
| Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. | Molecular cancer 20020101 |
| [Telomerase: an enzyme with multiple applications in cancer research]. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20020101 |
| Aberrant methylation of the 5' CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanlNs. | Cancer biology & therapy 20020101 |
| Chronic myelogenous leukemia. | Hematology. American Society of Hematology. Education Program 20020101 |
| Characteristic promoter hypermethylation signatures in male germ cell tumors. | Molecular cancer 20020101 |
| 5-aza-2'-deoxycytidine induces retinoic acid receptor beta 2 demethylation, cell cycle arrest and growth inhibition in breast carcinoma cells. | Anticancer research 20020101 |
| A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers. | Anticancer research 20020101 |
| Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide. | Cancer research 20011215 |
| Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma. | Cancer research 20011201 |
| Potential of 5-aza-2'-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20011201 |
| Reexpression of a cluster of silenced transgenes is associated with their rearrangement. | Genes, chromosomes & cancer 20011201 |
| Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer. | British journal of cancer 20011201 |
| [Chemotherapy and radiation therapy]. | Nihon rinsho. Japanese journal of clinical medicine 20011201 |
| Synthesis of oligonucleotide inhibitors of DNA (Cytosine-C5) methyltransferase containing 5-azacytosine residues at specific sites. | Antisense & nucleic acid drug development 20011201 |
| Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells. | Oncogene 20011122 |
| Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. | Cancer research 20011115 |
| 5-Aza-2'-deoxycytidine induces histone hyperacetylation of mouse centromeric heterochromatin by a mechanism independent of DNA demethylation. | Biochemical and biophysical research communications 20011109 |
| E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells. | Cancer letters 20011108 |
| Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis. | Oncogene 20011108 |
| Diminished expression of S100A2, a putative tumor suppressor, at early stage of human lung carcinogenesis. | Cancer research 20011101 |
| CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression. | Cancer research 20011101 |
| Glypican-3 expression is silenced in human breast cancer. | Oncogene 20011101 |
| Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas. | British journal of cancer 20011101 |
| Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer. | Human molecular genetics 20011101 |
| Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells. | The Journal of biological chemistry 20011026 |
| Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression. | Oncogene 20011025 |
| CpG hypermethylation of the promoter region inactivates the estrogen receptor-beta gene in patients with prostate carcinoma. | Cancer 20011015 |
| Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development. | The Journal of clinical investigation 20011015 |
| Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2'-deoxycytidine treatment. | International journal of cancer 20011015 |
| DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas. | Carcinogenesis 20011001 |
| Chloroplast DNA methylation and inheritance in Chlamydomonas. | Genes & development 20011001 |
| Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. | Cancer research 20011001 |
| Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma. | Cancer research 20011001 |
| Reduced expression of syndecan-1 affects metastatic potential and clinical outcome in patients with colorectal cancer. | Japanese journal of cancer research : Gann 20011001 |
| Pharmacological reactivation of inactive genes: the fragile X experience. | Brain research bulletin 20011001 |
| Histone deacetylase and DNA methyltransferase in human prostate cancer. | Biochemical and biophysical research communications 20010928 |
| Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma. | Cancer research 20010915 |
| Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer. | Oncogene 20010913 |
| Methylation status in the promoter region of the human PGP9.5 gene in cancer and normal tissues. | Cancer letters 20010910 |
| Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma. | International journal of cancer 20010901 |
| Hypermethylation of CpG islands in the mouse asparagine synthetase gene: relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in normal cells. | British journal of cancer 20010901 |
| CpG methylation of promoter region inactivates E-cadherin gene in renal cell carcinoma. | Molecular carcinogenesis 20010901 |
| Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma. | Molecular carcinogenesis 20010901 |
| Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. | Japanese journal of cancer research : Gann 20010901 |
| Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene. | Cancer gene therapy 20010901 |
| Evolving treatment options of myelodysplastic syndromes. | Annals of hematology 20010901 |
| Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences. | Oncogene 20010823 |
| Reversion of transcriptional repression of Sp1 by 5 aza-2' deoxycytidine restores TGF-beta type II receptor expression in the pancreatic cancer cell line MIA PaCa-2. | Cancer research 20010815 |
| Methylation of the E-cadherin gene promoter correlates with progression of prostate cancer. | The Journal of urology 20010801 |
| DNA methylation regulates placental lactogen I gene expression. | Endocrinology 20010801 |
| Activation of the maternally preset program of apoptosis by microinjection of 5-aza-2'-deoxycytidine and 5-methyl-2'-deoxycytidine-5'-triphosphate in Xenopus laevis embryos. | Development, growth & differentiation 20010801 |
| Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine. | British journal of haematology 20010801 |
| Hypermethylation leads to silencing of the SYK gene in human breast cancer. | Cancer research 20010715 |
| Regulation of the intestinal mucin MUC2 gene expression in vivo: evidence for the role of promoter methylation. | Cancer letters 20010710 |
| Promoter hypermethylation: a common cause of reduced p16(INK4a) expression in uveal melanoma. | Cancer research 20010701 |
| Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010701 |
| Loss of mismatch repair activity in simian virus 40 large T antigen-immortalized BPH-1 human prostatic epithelial cell line. | Molecular carcinogenesis 20010701 |
| Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. | Cancer chemotherapy and pharmacology 20010701 |
| Transcription regulation and protein subcellular localization of the truncated basic hair keratin hHb1-DeltaN in human breast cancer cells. | The Journal of biological chemistry 20010622 |
| Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. | Cancer research 20010615 |
| Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells. | Cancer research 20010601 |
| Decitabine with allogeneic peripheral blood stem cell transplantation in the therapy of leukemia relapse following a prior transplant: results of a phase I study. | Bone marrow transplantation 20010601 |
| Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer. | Cancer research 20010515 |
| Regulation of CD21 expression by DNA methylation and histone deacetylation. | International immunology 20010501 |
| 5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer. | Cancer research 20010501 |
| Identification of Arabidopsis histone deacetylase HDA6 mutants that affect transgene expression. | The Plant cell 20010501 |
| Epigenetic silencing of PEG3 gene expression in human glioma cell lines. | Molecular carcinogenesis 20010501 |
| The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells. | Human molecular genetics 20010415 |
| Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. | Annals of internal medicine 20010403 |
| Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine. | Molecular pharmacology 20010401 |
| Androgen receptor expression in androgen-independent prostate cancer cell lines. | The Prostate 20010401 |
| p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2. | Cancer research 20010401 |
| Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. | Cancer research 20010401 |
| Association of acetylated histones with paternally expressed genes in the Prader--Willi deletion region. | Human molecular genetics 20010315 |
| Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells. | Biochemical pharmacology 20010315 |
| Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease. | Current opinion in hematology 20010301 |
| Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas. | The American journal of pathology 20010301 |
| Analysis of the ANA gene as a candidate for the chromosome 21q oral cancer susceptibility locus. | British journal of cancer 20010301 |
| Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo. | International journal of cancer 20010301 |
| Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition. | Cancer research 20010301 |
| Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. | Cancer research 20010215 |
| DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. | Cancer research 20010215 |
| Unbalanced expression of HLA-A and -B antigens: a specific feature of cutaneous melanoma and other non-hemopoietic malignancies reverted by IFN-gamma. | International journal of cancer 20010215 |
| Effect of 5-Aza-2'-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2. | World journal of gastroenterology 20010215 |
| Site-specific methylation of the promoter alters deoxyribonucleic acid-protein interactions and prevents follicle-stimulating hormone receptor gene transcription. | Biology of reproduction 20010201 |
| Sensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3. | British journal of haematology 20010201 |
| Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice. | Cancer research 20010201 |
| Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. | Nature 20010111 |
| Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites. | The Journal of biological chemistry 20010105 |
| Biallelic inactivation of retinoic acid receptor beta2 gene by epigenetic change in breast cancer. | The American journal of pathology 20010101 |
| Progesterone receptor B gene inactivation and CpG hypermethylation in human uterine endometrial cancer. | Cancer research 20010101 |
| Induction of MAGE-3 expression in lung and esophageal cancer cells. | The Annals of thoracic surgery 20010101 |
| Sequential 5-Aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20010101 |
| Applications of microarray technology in breast cancer research. | Breast cancer research : BCR 20010101 |
| Autoreactive murine Th1 and Th2 cells kill syngeneic macrophages and induce autoantibodies. | Lupus 20010101 |
| Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties. | Nucleosides, nucleotides & nucleic acids 20010101 |
| Demethylation by 5-aza-2'-deoxycytidine (5-azadC) of p16INK4A gene results in downregulation of vascular endothelial growth factor expression in human lung cancer cell lines. | Oncology research 20010101 |
| The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression. | Breast cancer research : BCR 20010101 |
| Altered hox gene expression and cellular pathogenesis of 5-aza-2'-deoxycytidine-induced murine hindlimb dysmorphogenesis. | Toxicologic pathology 20010101 |
| Targeting hypomethylation of DNA to achieve cellular differentiation in myelodysplastic syndromes (MDS). | The oncologist 20010101 |
| Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties. | European journal of medicinal chemistry 20001101 |
| Pilot phase I-II study on 5-aza-2'-deoxycytidine (Decitabine) in patients with metastatic lung cancer. | Anti-cancer drugs 19970401 |
| Antiproliferative effects and DNA hypomethylation by 5-aza-2'-deoxycytidine in human neuroblastoma cell lines. | Anti-cancer drugs 19931201 |
| Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance. | Proceedings of the National Academy of Sciences of the United States of America 19930401 |
| The effect of anti-neoplastic drugs on murine acquired immunodeficiency syndrome. | Science (New York, N.Y.) 19910118 |
| Increased sensitivity of nontumorigenic fibroblasts expressing ras or myc oncogenes to malignant transformation induced by 5-aza-2'-deoxycytidine. | Cancer research 19910101 |
| 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro. | Antimicrobial agents and chemotherapy 19900201 |
| Increased metallothionein gene expression in 5-aza-2'-deoxycytidine-induced resistance to cadmium cytotoxicity. | Chemico-biological interactions 19880101 |
| Cellular differentiation, cytidine analogs and DNA methylation. | Cell 19800501 |