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Mtt formazan

CAS No.:
23305-68-2
Catalog Number:
AG002MUC
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
>98.0%(HPLC)
1 week
United States
$62
- +
Product Description
Catalog Number:
AG002MUC
Chemical Name:
Mtt formazan
CAS Number:
23305-68-2
MDL Number:
MFCD00080731
IUPAC Name:
N'-anilino-N-[(4,5-dimethyl-1,3-thiazol-2-yl)imino]benzenecarboximidamide
InChI:
InChI=1S/C18H17N5S/c1-13-14(2)24-18(19-13)23-22-17(15-9-5-3-6-10-15)21-20-16-11-7-4-8-12-16/h3-12,20H,1-2H3
InChI Key:
GIFKVQOPAJDJLO-UHFFFAOYSA-N
EC Number:
245-566-1
Properties
Complexity:
441  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
335.12g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
335.429g/mol
Monoisotopic Mass:
335.12g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
90.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
1  
XLogP3:
5.9  
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Amyloid toxicity is independent of polypeptide sequence, length and chirality. Journal of molecular biology 20080118
LRRC4 inhibits glioblastoma cell proliferation, migration, and angiogenesis by downregulating pleiotropic cytokine expression and responses. Journal of cellular physiology 20080101
Mitral valvular interstitial cells demonstrate regional, adhesional, and synthetic heterogeneity. Cells, tissues, organs 20080101
The use of High Performance Thin-Layer Chromatography to determine the role of membrane lipid composition in bile salt-induced kidney cell damage. Journal of pharmacological and toxicological methods 20080101
A comparison of the apoptotic and cytotoxic effects of hexanedione derivatives on human non-neuronal lines and the neuroblastoma line SH-SY5Y. Basic & clinical pharmacology & toxicology 20080101
An in-vivo assay to identify compounds protective against light induced apoptosis. Advances in experimental medicine and biology 20080101
Photooxidative action in cancer and normal cells induced by the use of photofrin in photodynamic therapy. Folia biologica 20080101
Expression and hydroxylamine cleavage of thymosin alpha 1 concatemer. Journal of biomedicine & biotechnology 20080101
Upon oxidative stress, the antiapoptotic Hsp60/procaspase-3 complex persists in mucoepidermoid carcinoma cells. European journal of histochemistry : EJH 20080101
Transcriptional regulation of IL-8 by iron chelator in human epithelial cells is independent from NF-kappaB but involves ERK1/2- and p38 kinase-dependent activation of AP-1. Journal of cellular biochemistry 20071215
Suppression by glutamate of proliferative activity through glutathione depletion mediated by the cystine/glutamate antiporter in mesenchymal C3H10T1/2 stem cells. Journal of cellular physiology 20071201
In vitro induction of cytotoxicity and DNA strand breaks in CHO cells exposed to cypermethrin, pendimethalin and dichlorvos. Toxicology in vitro : an international journal published in association with BIBRA 20071201
Nrf2-mediated heme oxygenase-1 induction confers adaptive survival response to tetrahydropapaveroline-induced oxidative PC12 cell death. Antioxidants & redox signaling 20071201
Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner. Antioxidants & redox signaling 20071201
Effects of regulatory factors on engineered cardiac tissue in vitro. Tissue engineering 20071101
A new quantitative in vitro microculture method for Giardia duodenalis trophozoites. Journal of microbiological methods 20071101
Resistance to Ara-C up-regulates the activation of NF-kappaB, telomerase activity and Fas expression in NALM-6 cells. Biological & pharmaceutical bulletin 20071101
Comparison of basal gene expression and induction of CYP3As in HepG2 and human fetal liver cells. Biological & pharmaceutical bulletin 20071101
Effect of L-cycloserine on cellular responses mediated by macrophages and T cells. Biological & pharmaceutical bulletin 20071101
(R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. The Journal of biological chemistry 20071026
Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis. Biochemistry 20071023
Cell-surface interactions of rat tooth germ cells on various biomaterials. Journal of biomedical materials research. Part A 20071001
The gene transfection efficiency of thermoresponsive N,N,N-trimethyl chitosan chloride-g-poly(N-isopropylacrylamide) copolymer. Biomaterials 20071001
DNA binding properties and evaluation of cytotoxic activity of 9,10-bis-N-substituted (aminomethyl)anthracenes. International journal of biological macromolecules 20071001
The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro. Investigative ophthalmology & visual science 20071001
A rapid colorimetric assay for the quantitation of the viability of free-living larvae of nematodes in vitro. Parasitology research 20070901
Apoptotic action of peroxisome proliferator-activated receptor-gamma activation in human non small-cell lung cancer is mediated via proline oxidase-induced reactive oxygen species formation. Molecular pharmacology 20070901
Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of peroxisome proliferator-activated receptor gamma. Molecular pharmacology 20070901
Proteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma. Proteomics 20070901
Contribution of MX dynamin, oligoadenylate synthetase, and protein kinase R to anti-paramyxovirus activity of type 1 interferons in vitro. American journal of veterinary research 20070901
Formulations of biodegradable Nanogel carriers with 5'-triphosphates of nucleoside analogs that display a reduced cytotoxicity and enhanced drug activity. Journal of controlled release : official journal of the Controlled Release Society 20070816
Efficient protection by cationized catalase against H2O2 injury in primary cultured alveolar epithelial cells. Journal of controlled release : official journal of the Controlled Release Society 20070816
Cholesterol inhibits MMP-9 expression in human epidermal keratinocytes and HaCaT cells. FEBS letters 20070807
Damage effects of dust storm PM2.5 on DNA in alveolar macrophages and lung cells of rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070801
Poly(N-isopropylacrylamide)-chitosan as thermosensitive in situ gel-forming system for ocular drug delivery. Journal of controlled release : official journal of the Controlled Release Society 20070731
Cardosins: a new and efficient plant enzymatic tool to dissociate neuronal cells for the establishment of cell cultures. Biotechnology and bioengineering 20070701
The effect of three-dimensional demineralized bone matrix on in vitro cumulus-free oocyte maturation. Biomaterials 20070701
Methylmercury-induced changes in mitochondrial function in striatal synaptosomes are calcium-dependent and ROS-independent. Neurotoxicology 20070701
The effect of strontium incorporation into CaSiO3 ceramics on their physical and biological properties. Biomaterials 20070701
Influence of engineered titania nanotubular surfaces on bone cells. Biomaterials 20070701
Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24). Biochemical pharmacology 20070615
Evaluation of the biological responses of osteoblast-like UMR-106 cells to the engineered porous PHBV matrix. Journal of biomedical materials research. Part A 20070601
Fast and efficient screening system for new biomaterials in tissue engineering: a model for peripheral nerve regeneration. Journal of biomedical materials research. Part A 20070601
LC-MS characterization of efficacy substances in serum of experimental animals treated with Sophora flavescens extracts. Biomedical chromatography : BMC 20070601
A transmissible cytotoxic activity isolated from a patient with brain ischemia causes microglial cell activation and dysfunction. Cellular and molecular neurobiology 20070601
JWA gene is involved in cadmium-induced growth inhibition and apoptosis in HEK-293T cells. Journal of toxicology and environmental health. Part A 20070601
The role of oxidative stress in hormesis induced by sodium arsenite in human embryo lung fibroblast (HELF) cellular proliferation model. Journal of toxicology and environmental health. Part A 20070601
Biological characteristics of Chinese hamster ovary cells transfected with bovine Prnp. Journal of veterinary science 20070601
4-Hydroxykobusin inhibits the induction of nitric oxide synthase by inhibiting NF-kappaB and AP-1 activation. Biological & pharmaceutical bulletin 20070601
Apoptosis-inducing activity of new pyrazole emodin derivatives in human hepatocellular carcinoma HepG2 cells. Biological & pharmaceutical bulletin 20070601
L-carnitine protects human retinal pigment epithelial cells from oxidative damage. Current eye research 20070601
Antioxidant activity and cytotoxicity study of the flavonol glycosides from Bauhinia galpinii. Natural product research 20070601
A new anticancer dihydroflavanoid from the root of Spiranthes australis (R. Brown) Lindl. Natural product research 20070601
Macrocyclic copper(II) complexes: superoxide scavenging activity, structural studies and cytotoxicity evaluation. Journal of inorganic biochemistry 20070501
The suppressive effect of beta-glucan on the production of tumor necrosis factor-alpha in BV2 microglial cells. Bioscience, biotechnology, and biochemistry 20070501
Inhibitory effect of fulvic acid extracted from Canadian sphagnum peat on chemical mediator release by RBL-2H3 and KU812 cells. Bioscience, biotechnology, and biochemistry 20070501
Cadmium cation increases the production and mRNA levels of insulin-like growth factor-binding protein-1 in HepG2. Bioscience, biotechnology, and biochemistry 20070501
Protective effect of a novel cystine C(60) derivative on hydrogen peroxide-induced apoptosis in rat pheochromocytoma PC12 cells. Chemico-biological interactions 20070425
Combined effects of mycotoxin mixtures on human T cell function. Toxicology letters 20070425
Cadmium induces apoptosis in human embryonic kidney (HEK) 293 cells by caspase-dependent and -independent pathways acting on mitochondria. Toxicology in vitro : an international journal published in association with BIBRA 20070401
Interleukin-1beta expression in murine J774A.1 macrophages exposed to platinum compounds: the role of p38 and ERK 1/2 mitogen-activated protein kinases. Toxicology in vitro : an international journal published in association with BIBRA 20070401
In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells. Toxicology in vitro : an international journal published in association with BIBRA 20070401
Occult cardiotoxicity: subtoxic dosage of Bis(2-chloroethoxy)methane impairs cardiac response to simulated ischemic injury. Toxicologic pathology 20070401
New pyrazolic compounds as cytotoxic agents. Natural product research 20070401
Chemical-physical and preliminary biological properties of poly (2-hydroxyethylmethacrylate)/poly-(epsilon-caprolactone)/hydroxyapa- tite composite. Journal of materials science. Materials in medicine 20070401
Truncations of gelonin lead to a reduction in its cytotoxicity. Toxicology 20070307
Apoptotic and necrotic effects of hexanedione derivatives on the human neuroblastoma line SK-N-SH. Toxicology 20070307
In vitro apoptotic activity of 2,2-diphenyl-1,3,2-oxazaborolidin-5-ones in L5178Y cells. Life sciences 20070220
Role of glutathione in determining the differential sensitivity between the cortical and cerebellar regions towards mercury-induced oxidative stress. Toxicology 20070212
Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer. International journal of pharmaceutics 20070207
MZ3 induces apoptosis in human leukemia cells. Cancer chemotherapy and pharmacology 20070201
Optimized candidal biofilm microtiter assay. Journal of microbiological methods 20070201
Comparison of in vitro toxicity of single vs double exposures of indocyanine green in human retinal pigment epithelial cell cultures. American journal of ophthalmology 20070201
Construction of eukaryotic expression plasmid of bFGF gene in rats and its expression in tenocytes. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070201
Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity. Brain research 20070126
Connective tissue growth factor and fibronectin secretion in renal tubular epithelial cells induced by TGF-beta1: suppressive effects of troglitazone. Cell biology international 20070101
The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells. Molecular cancer therapeutics 20070101
Inhibitory effects of natural plants of Jeju Island on elastase and MMP-1 expression. Journal of cosmetic science 20070101
In vitro study of biofunctional indicators after exposure to asbestos-like fluoro-edenite fibres. Cellular and molecular biology (Noisy-le-Grand, France) 20070101
Localization of MTT formazan in lipid droplets. An alternative hypothesis about the nature of formazan granules and aggregates. European journal of histochemistry : EJH 20070101
Smart and cationic poly(NIPA)/PEI block copolymers as non-viral vectors: in vitro and in vivo transfection studies. Journal of tissue engineering and regenerative medicine 20070101
Efficiency of two different transfection reagents for use with human NTERA2 cells. European journal of histochemistry : EJH 20070101
Influence of synovial fluid on human osteoblasts: an in vitro study. TheScientificWorldJournal 20070101
Two new chemical constituents from Daphne odora Thunb. var. marginata. Natural product research 20061201
In vitro cytotoxic activities of (+)-usnic acid and (-)-usnic acid on V79, A549, and human lymphocyte cells and their non-genotoxicity on human lymphocytes. Natural product research 20061201
9-epi-Viridiol, a novel cytotoxic furanosteroid from soil fungus Trichoderma virens. Natural product research 20061201
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology 20061110
Effect of naringin on bone cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20061101
The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine. Cell biology and toxicology 20061101
Development of an in vitro model for study of the efficacy of ischemic preconditioning in human skeletal muscle against ischemia-reperfusion injury. Journal of applied physiology (Bethesda, Md. : 1985) 20061101
One new anthraquinone from marine Streptomyces sp. FX-58. Natural product research 20061101
Mechanical loading modulates the differentiation state of vascular smooth muscle cells. Tissue engineering 20061101
The formation of bioactive amyloid species by prion proteins in vitro and in cells. Neuroscience letters 20061009
Toxic effects of povidone-iodine on synovial cell and articular cartilage. Clinical rheumatology 20060901
Antagonistic effects of methyl-mercury and PCB153 on PC12 cells after a combined and simultaneous exposure. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060901
Adverse effects of T-2 toxin on chicken lymphocytes blastogenesis and its protection with Vitamin E. Toxicology 20060815
Inhibition of respiratory syncytial virus in cultured cells by nucleocapsid gene targeted deoxyribozyme (DNAzyme). Antiviral research 20060801
A colorimetric assay for viral agents that produce cytopathic effects. Journal of virological methods 20060701
Adrenomedullin inhibits insulin exocytosis via pertussis toxin-sensitive G protein-coupled mechanism. American journal of physiology. Endocrinology and metabolism 20060701
Rapid, multiwell colorimetric assay for measuring neutrophil chemoattractant activity in bronchoalveolar lavage fluid of horses with recurrent airway obstruction. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20060501
Candidacidal activity of a monoclonal antibody that binds with glycosyl moieties of proteins of Candida albicans. Medical mycology 20060301
Bombesin/gastrin-releasing peptide receptor antagonists increase the ability of histone deacetylase inhibitors to reduce lung cancer proliferation. Journal of molecular neuroscience : MN 20060101
PMA and doxorubicin decrease viability, MTT activity and expression of CD10 marker on NALM-1 leukemic cells. Immunopharmacology and immunotoxicology 20060101
Biological inhibitory effects of the Chinese herb danggui on brain astrocytoma. Pathobiology : journal of immunopathology, molecular and cellular biology 20060101
Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents. Clinical & experimental metastasis 20060101
A search for multidrug resistance modulators: the effects of retinoids in human colon carcinoma cells. In vivo (Athens, Greece) 20060101
Early phase of amyloid beta42-induced cytotoxicity in neuronal cells is associated with vacuole formation and enhancement of exocytosis. Experimental & molecular medicine 20051231
15-Deoxy-delta12,14-prostaglandin J2, a neuroprotectant or a neurotoxicant? Toxicology 20051215
Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicology and applied pharmacology 20051201
Protective and detrimental effects of kaempferol in rat H4IIE cells: implication of oxidative stress and apoptosis. Toxicology and applied pharmacology 20051201
Immune modulatory effects of Prunella vulgaris L. on monocytes/macrophages. International journal of molecular medicine 20051201
Inhibition of host peripheral blood mononuclear cell proliferation ex vivo by Rinderpest virus. The Journal of general virology 20051201
A pair of isomeric saponins with cytotoxicity from Albizzia julibrissin. Journal of Asian natural products research 20051201
Two new triterpenoid saponins from Symplocos chinensis. Journal of Asian natural products research 20051201
Anti-inflammatory effects of indomethacin's methyl ester derivative and induction of apoptosis in HL-60 Cells. Biological & pharmaceutical bulletin 20051201
Effect of GnRH analogs on the expression of TrkA and p75 neurotrophin receptors in primary cell cultures from human prostate adenocarcinoma. The Prostate 20051101
Induction of manganese superoxide dismutase (MnSOD) mediates cardioprotective effect of tamoxifen (TAM). Journal of molecular and cellular cardiology 20051101
Investigation of the effects of deracoxib and piroxicam on the in vitro viability of osteosarcoma cells from dogs. American journal of veterinary research 20051101
Loss of functional E-cadherin renders cells more resistant to the apoptotic agent taxol in vitro. Experimental cell research 20051015
Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology 20050915
Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2. Toxicology 20050915
Effect of NQO1 induction on the antitumor activity of RH1 in human tumors in vitro and in vivo. Cancer chemotherapy and pharmacology 20050901
Effects on protein and mRNA expression levels of p53 induced by fluoride in human embryonic hepatocytes. Toxicology letters 20050814
Effects of coumarin and 7OH-coumarin on bcl-2 and Bax expression in two human lung cancer cell lines in vitro. Cell biology international 20050801
The release of microparticles by apoptotic cells and their effects on macrophages. Apoptosis : an international journal on programmed cell death 20050801
Cytotrophoblast differentiation in the first trimester of pregnancy: evidence for separate progenitors of extravillous trophoblasts and syncytiotrophoblast. Reproduction (Cambridge, England) 20050701
Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro. Cancer letters 20050616
Receptor for advanced glycation end products (RAGE) and its ligand, amphoterin are overexpressed and associated with prostate cancer development. The Prostate 20050615
UV induced bystander signaling leading to apoptosis. Cancer letters 20050608
Prediction of poor survival by cyclooxygenase-2 in patients with T4 nasopharyngeal cancer treated by radiation therapy: clinical and in vitro studies. Head & neck 20050601
Synthesis and evaluation of double bond substituted combretastatins. European journal of medicinal chemistry 20050601
Cytotoxic activity of new lanthanum (III) complexes of bis-coumarins. European journal of medicinal chemistry 20050601
Synthesis, physicochemical and in vitro pharmacological investigation of new platinum (II) complexes with some cycloalkanespiro-5'-hydantoins. European journal of medicinal chemistry 20050601
Evaluation of transferrin-polyethylenimine conjugate for targeted gene delivery. Archives of pharmacal research 20050601
Differentiation of human bone marrow stromal cells into neural-like cells induced by sodium ferulate in vitro. Cellular & molecular immunology 20050601
Toxic potential of five freshwater Phormidium species (Cyanoprokaryota). Toxicon : official journal of the International Society on Toxinology 20050501
Immunomodulatory mechanism of the aqueous extract of sword brake fern (Pteris ensiformis Burm.). Journal of ethnopharmacology 20050408
Isoflavonoids from Astragalus mongholicus protect PC12 cells from toxicity induced by L-glutamate. Journal of ethnopharmacology 20050408
Comparison of three cytotoxicity tests in the evaluation of the cytotoxicity of a spermine analogue on human breast cancer cell lines. Toxicology in vitro : an international journal published in association with BIBRA 20050401
Comparative evaluation of the nitrate reduction assay, the MTT test, and the resazurin microtitre assay for drug susceptibility testing of clinical isolates of Mycobacterium tuberculosis. The Journal of antimicrobial chemotherapy 20050401
The evaluation of cytotoxic activity of planar pentadentate ligand 2',2''-(2,6-pyridindiyldiethylidyne) dioxamohydrazide dihydrate (H2l x 2H2O) and its metal coordination complexes; pitfalls in the use of the MTT-assay. Journal of experimental & clinical cancer research : CR 20050301
Mitogen-induced lymphocyte proliferation in loggerhead sea turtles: comparison of methods and effects of gender, plasma testosterone concentration, and body condition on immunity. Veterinary immunology and immunopathology 20050210
Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202
Beta-carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway. Neuropharmacology 20050101
Kinetics of MTT-formazan exocytosis in phagocytic and non-phagocytic cells. Micron (Oxford, England : 1993) 20050101
Determinants of cisplatin and irinotecan activities in human lung adenocarcinoma cells: evidence of cisplatin accumulation and topoisomerase I activity. In vivo (Athens, Greece) 20050101
Lysostaphin as a potential therapeutic agent for staphylococcal biofilm eradication. Polish journal of microbiology 20050101
Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. International immunopharmacology 20041215
Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells. Toxicology letters 20041201
The MTT assays of bovine retinal pericytes and human microvascular endothelial cells on DLC and Si-DLC-coated TCPS. Journal of biomedical materials research. Part A 20041101
Detecting bioactive amyloid beta peptide species in Alzheimer's disease. Journal of neurochemistry 20041101
Experimental survey of non-clonogenic viability assays for adherent cells in vitro. Toxicology in vitro : an international journal published in association with BIBRA 20041001
In vitro alveolar cytotoxicity of soluble components of airborne particulate matter: effects of serum on toxicity of transition metals. Toxicology in vitro : an international journal published in association with BIBRA 20041001
Comparison of alamar blue and MTT assays for high through-put screening. Toxicology in vitro : an international journal published in association with BIBRA 20041001
Synergistic interaction between gefitinib (Iressa, ZD1839) and paclitaxel against human gastric carcinoma cells. Anti-cancer drugs 20040901
Cancer chemoprevention by the antioxidant tempol in Atm-deficient mice. Human molecular genetics 20040815
Echinomycin and a novel analogue induce apoptosis of HT-29 cells via the activation of MAP kinases pathway. Pharmacological research 20040801
Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukemia and lymphoma cells by induction of apoptosis. Life sciences 20040702
Genotoxicity of the isoflavones genistein, daidzein and equol in V79 cells. Toxicology letters 20040615
The apoptotic and necrotic effects of tomatine adjuvant. Vaccine 20040602
A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction. Toxicology 20040601
The permeability and cytotoxicity of insulin-mimetic vanadium compounds. Pharmaceutical research 20040601
Backscattered light confocal imaging of intracellular MTT-formazan crystals. Microscopy research and technique 20040601
Hormesis effect of trace metals on cultured normal and immortal human mammary cells. Toxicology and industrial health 20040601
Cellular features of an apoptotic form of programmed cell death during the development of the ascidian, Boltenia villosa. Zoological science 20040501
Cytotoxic effects of pyocin S2 produced by Pseudomonas aeruginosa on the growth of three human cell lines. Canadian journal of microbiology 20040501
The in vitro interaction of Sporothrix schenckii with human endothelial cells is modulated by cytokines and involves endothelial surface molecules. Microbial pathogenesis 20040401
Functional integrity of precision-cut liver slices from deer and cattle. Journal of veterinary pharmacology and therapeutics 20040401
Reduction of photosystem I reaction center in DrgA mutant of the cyanobacterium Synechocystis sp. PCC 6803 lacking soluble NAD(P)H:quinone oxidoreductase. Biochemistry. Biokhimiia 20040401
Synthesis and biological evaluation of 6-substituted purine and 9-beta-d-ribofuranosyl purine analogues. Bioorganic & medicinal chemistry 20040315
Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat lung epithelial cells. Journal of veterinary science 20040301
Inhibition of beta-amyloid toxicity by short peptides containing N-methyl amino acids. The journal of peptide research : official journal of the American Peptide Society 20040301
Cytotoxicity evaluation after coexposure to perchloroethylene and selected peroxidant drugs in rat hepatocytes. Toxicology in vitro : an international journal published in association with BIBRA 20040201
Phase I and phase II metabolic activities are retained in liver slices from mouse, rat, dog, monkey and human after cryopreservation. Toxicology in vitro : an international journal published in association with BIBRA 20040201
Estrogen altered oral tolerance induction in type II collagen-induced murine arthritis. International archives of allergy and immunology 20040101
Repeatability of flow cytometric and classical measurement of phagocytosis and respiratory burst in bovine polymorphonuclear leukocytes. Veterinary immunology and immunopathology 20040101
Morphological and intracellular alterations induced by Serratia marcescens cytotoxin. Research in microbiology 20040101
Genetic resistance of Egyptian chickens to infectious bursal disease and Newcastle disease. Tropical animal health and production 20040101
Erianin induces a JNK/SAPK-dependent metabolic inhibition in human umbilical vein endothelial cells. In vivo (Athens, Greece) 20040101
A scalable high-content cytotoxicity assay insensitive to changes in mitochondrial metabolic activity. Oncology research 20040101
Low concentration of oxidant and nitric oxide donors stimulate proliferation of human endothelial cells in vitro. Cell biology international 20040101
Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line. In vitro cellular & developmental biology. Animal 20040101
Cytotoxicity evaluation of soft contact lens care solutions on human conjunctival fibroblasts. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20040101
Flavopiridol as a radio-sensitizer for esophageal cancer cell lines. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20040101
Anti-tumor effect of ascorbic acid, lysine, proline, arginine, and epigallocatechin gallate on prostate cancer cell lines PC-3, LNCaP, and DU145. Research communications in molecular pathology and pharmacology 20040101
Switching off HSP70 and i-NOS to study their role in normal and H2O2-stressed human fibroblasts. Life sciences 20031226
The protective effect of ascorbic acid derivative on PC12 cells: involvement of its ROS scavenging ability. Life sciences 20031226
The effects of albendazole and its metabolites on hepatic cytochromes P450 activities in mouflon and rat. Research in veterinary science 20031201
Altered maturation of dendritic cells by taxol, an anticancer drug. Journal of veterinary science 20031201
Effect of ofloxacin and netilmicin on human corneal and conjunctival cells in vitro. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201
Identification of common or distinct genes related to antitumor activities of a medicinal herb and its major component by oligonucleotide microarray. International journal of cancer 20031120
Cytotoxicity of S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl) vinyl ether (Compound A) in a human proximal tubular cell line. Toxicology and applied pharmacology 20031115
Appraisal of the MTT-based assay as a useful tool for predicting drug chemosensitivity in leukemia. Leukemia & lymphoma 20031101
Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology 20031001
Chemosensitivity testing for gastrointestinal cancer: survival benefit potential and limitations. Anti-cancer drugs 20031001
Antioxidants protect primary rat hepatocyte cultures against acetaminophen-induced DNA strand breaks but not against acetaminophen-induced cytotoxicity. Toxicology 20030930
Effects of metals Cu, Fe, Ni, V, and Zn on rat lung epithelial cells. Toxicology 20030828
The effects of benzimidazole anthelmintics on P4501A in rat hepatocytes and HepG2 cells. Research in veterinary science 20030801
Rhodamine B as a mitochondrial probe for measurement and monitoring of mitochondrial membrane potential in drug-sensitive and -resistant cells. Journal of biochemical and biophysical methods 20030731
Anti-HBV effect of TAT- HBV targeted ribonuclease. World journal of gastroenterology 20030715
Inhibition of glycyrrhizic acid on aflatoxin B1-induced cytotoxicity in hepatoma cells. Toxicology 20030630
Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells. Cancer letters 20030610
Immunotoxicity of epicutaneously applied anticoagulant rodenticide warfarin: evaluation by contact hypersensitivity to DNCB in rats. Toxicology 20030603
Cytokine release from osteoblasts in response to ultrasound stimulation. Biomaterials 20030601
Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. British journal of pharmacology 20030601
A rapid MTT colorimetric assay to assess the proliferative index of two Indian strains of Theileria annulata. Veterinary parasitology 20030501
3-nitropropionic acid inhibition of succinate dehydrogenase (complex II) activity in cultured Chinese hamster ovary cells: antagonism by L-carnitine. Annals of the New York Academy of Sciences 20030501
The effect of m-xylene on cytotoxicity and cellular antioxidant status in rat dermal equivalents. Toxicology letters 20030430
Warifteine and milonine, alkaloids isolated from Cissampelos sympodialis Eichl: cytotoxicity on rat hepatocyte culture and in V79 cells. Toxicology letters 20030430
Heat preconditioning prevents oxidative stress-induced damage in the intestine and lung following surgical manipulation. The British journal of surgery 20030401
Possible chemoresistance-related genes for gastric cancer detected by cDNA microarray. Cancer science 20030401
Inhibition of HSV-1 replication and reactivation by the mutation-insensitive transcription inhibitor tetra-O-glycyl-nordihydroguaiaretic acid. Antiviral research 20030301
Deltamethrin induces apoptotic cell death in cultured cerebral cortical neurons. Toxicology and applied pharmacology 20030215
Morphological and immunological evidence of a unique selective production and endoplasmic reticular accumulation of interleukin-1alpha in rat peritoneal macrophages induced by Pseudomonas aeruginosa exotoxin A. Cellular immunology 20030201
The use of the MTT assay to study drug resistance in fresh tumour samples. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20030101
Maillard reaction products modulating the growth of human tumor cells in vitro. Chemical research in toxicology 20030101
Study of the potential cytotoxicity of dental impression materials. Toxicology in vitro : an international journal published in association with BIBRA 20030101
Fumonisin and beauvericin induce apoptosis in turkey peripheral blood lymphocytes. Mycopathologia 20030101
Mutations induced by 1,3-butadiene metabolites, butadiene diolepoxide, and 1,2,3,4-diepoxybutane at the Hprt locus in CHO-K1 cells. Molecules and cells 20021231
Inhibition of lung metastasis of osteosarcoma cell line POS-1 transplanted into mice by thigh ligation. Cancer letters 20021215
Determination of pretransplant viability of Leydig cells by MTT colorimetric assay. Transplantation proceedings 20021201
Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors. Chemico-biological interactions 20021110
Mechanisms of idiosyncratic drug reactions: the case of felbamate. Chemico-biological interactions 20021110
Cytotoxicity and oxidative mechanisms of different forms of chromium. Toxicology 20021030
Predictive ability of reconstructed human epidermis equivalents for the assessment of skin irritation of cosmetics. Toxicology in vitro : an international journal published in association with BIBRA 20021001
Involvement of tumor necrosis factor (TNF-alpha) in arsenic trioxide induced apoptotic cell death of murine myeloid leukemia cells. Toxicology letters 20020905
Screening of selected plant extracts for in vitro inhibitory activity on human immunodeficiency virus. Phytotherapy research : PTR 20020901
PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells. Oncogene 20020808
Antibacterial activity against resistant bacteria and cytotoxicity of four alkaloid toxins isolated from the marine sponge Arenosclera brasiliensis. Toxicon : official journal of the International Society on Toxinology 20020701
Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicology and applied pharmacology 20020701
Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene 20020606
A tactic for screening inhibitors of interleukin-2 production. Analytical biochemistry 20020601
In vitro effects of antibiotics on Brugia malayi worm survival and reproduction. The Journal of parasitology 20020601
Plasma concentrations of tumor necrosis factor-alpha in cats with congestive heart failure. American journal of veterinary research 20020501
Decrease in growth factor receptors after treatment with serine protease inhibitor ONO-3403. International journal of oncology 20020401
Effects of several flavonoids on the growth of B16F10 and SK-MEL-1 melanoma cell lines: relationship between structure and activity. Melanoma research 20020401
Aloe emodin suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture. Pharmacology & toxicology 20020401
New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation. Bioorganic & medicinal chemistry letters 20020311
Islet-neogenesis-associated protein enhances neurite outgrowth from DRG neurons. Biochemical and biophysical research communications 20020301
Cytotoxic effects of diazenes on tumor cells in vitro. Chemotherapy 20020301
Cytotoxic diterpenoids from Euphorbia pekinensis. Planta medica 20020301
[Detection of cell apoptosis by MTT assay]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020301
[Relation between the expression of P-gp and GST-pi in oral and maxillofacial squamous carcinoma and chemoresistance]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20020301
Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice. International journal of cancer 20020220
Variation in mitochondrial function in hypoxia-sensitive and hypoxia-tolerant human glioma cells. British journal of cancer 20020212
Mechanism of Impila (Callilepis laureola)-induced cytotoxicity in Hep G2 cells. Clinical biochemistry 20020201
Amyloid-beta-protein (A beta) (25-35)-associated free radical generation is strongly influenced by the aggregational state of the peptides. Life sciences 20020104
Cell cycle arrest and the induction of apoptosis in pancreatic cancer cells exposed to adenosine triphosphate in vitro. Oncology reports 20020101
Potentiated antitumor effects of butyrate and actinomycin D in melanoma model in mice. Oncology reports 20020101
Synergistic effects of topoisomerase I inhibitor, 7-ethyl-10-hydroxycamptothecin, and irradiation in a cisplatin-resistant human small cell lung cancer cell line. Clinical cancer research : an official journal of the American Association for Cancer Research 20020101
Differential chemosensitivity in a child with congenital relapsing acute lymphoblastic leukemia. Pediatric hematology and oncology 20020101
Antiviral activity of brassinosteroids derivatives against measles virus in cell cultures. Antiviral chemistry & chemotherapy 20020101
Long-term in vitro toxicity models: comparisons between a flow-cell bioreactor, a static-cell bioreactor and static cell cultures. Alternatives to laboratory animals : ATLA 20020101
Cytotoxic and radical scavenging activity of blended herbal extracts. In vivo (Athens, Greece) 20020101
Size effects of realgar particles on apoptosis in a human umbilical vein endothelial cell line: ECV-304. Pharmacological research 20011201
Beta-carotene inhibits growth of human colon carcinoma cells in vitro by induction of apoptosis. Biological chemistry 20011201
Characterization of toxin from cheilanthes fern and its effect on lymphocyte proliferation and DNA fragmentation. Indian journal of experimental biology 20011001
Mycobacterium phlei as an oral immunomodulator with Newcastle disease vaccine. Indian journal of experimental biology 20011001
Synergistic interaction between topotecan and microtubule-interfering agents. Cancer chemotherapy and pharmacology 20010901
Protective effect of 4',5-dihydroxy-3',6,7-trimethoxyflavone from Artemisia asiatica against Abeta-induced oxidative stress in PC12 cells. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20010901
Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free radical biology & medicine 20010815
Direct effect of Taxol on free radical formation and mitochondrial permeability transition. Free radical biology & medicine 20010815
Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis. British journal of cancer 20010801
Protective effects of antioxidants against smokeless tobacco-induced oxidative stress and modulation of Bcl-2 and p53 genes in human oral keratinocytes. Free radical research 20010801
The composition-dependent presence of free (micellar) alkylphospholipid in liposomal formulations of octadecyl-1,1-dimethyl-piperidino-4-yl-phosphate affects its cytotoxic activity in vitro. The Journal of membrane biology 20010701
alpha1-Adrenoceptors during simulated ischemia and reoxygenation of the human myocardium: effect of the dose and time of administration. The Journal of thoracic and cardiovascular surgery 20010701
Model for assessment of endothelial cell function and viability using the MTT dye test and [3H]. The Central African journal of medicine 20010701
Non-fibrillar oligomeric species of the amyloid ABri peptide, implicated in familial British dementia, are more potent at inducing apoptotic cell death than protofibrils or mature fibrils. Journal of molecular biology 20010629
Effects of Lewisite on cell membrane integrity and energy metabolism in human keratinocytes and SCL II cells. Toxicology 20010621
Evaluation of hepatic subcellular fractions for Alamar blue and MTT reductase activity. Toxicology in vitro : an international journal published in association with BIBRA 20010601
Antitumor bicyclic hexapeptide RA-VII modulates cyclin D1 protein level. Anti-cancer drugs 20010601
Species- and sex-specific renal cytotoxicity of ochratoxin A and B in vitro. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20010601
Peripheral blood granulocyte activity following contact sensitization of rats with dinitrochlorobenzene. Toxicology 20010511
2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells. Toxicological sciences : an official journal of the Society of Toxicology 20010501
Mitosis and differentiation in T-cells under cytotoxic action of Echinococcus granulosus hydatid fluid. Veterinary parasitology 20010419
Resistance to growth inhibitory and apoptotic effects of phorbol ester and UCN-01 in aggressive cancer cell lines. International journal of oncology 20010401
Anti-human immunodeficiency virus activity of YK-FH312 (a betulinic acid derivative), a novel compound blocking viral maturation. Antimicrobial agents and chemotherapy 20010401
Cytotoxicity effects of di- and tri-hydroxybenzaldehydes as a chemopreventive potential agent on tumor cells. Toxicology 20010328
Detection of drug-induced, superoxide-mediated cell damage and its prevention by antioxidants. Free radical biology & medicine 20010315
Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML. British journal of cancer 20010301
Assay of sperm quality in the domestic fowl by MTT reduction. British poultry science 20010301
Application of an MTT reduction assay for assessing sperm quality and predicting fertilising ability of domestic fowl semen. British poultry science 20010301
A cell-based method for the detection of nanomolar concentrations of bioactive amyloid. Analytical biochemistry 20010215
Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells. Molecular carcinogenesis 20010201
Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi. Blood 20010115
Effect of growth medium on potential of Streptomyces Anulatus spores to induce inflammatory responses and cytotoxicity in RAW264.7 macrophages. Inhalation toxicology 20010101
Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications. Clinical cancer research : an official journal of the American Association for Cancer Research 20010101
Ecteinascidin 743 induces protein-linked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression. Clinical cancer research : an official journal of the American Association for Cancer Research 20010101
The use of cultured hepatocytes to investigate the metabolism of drugs and mechanisms of drug hepatotoxicity. Alternatives to laboratory animals : ATLA 20010101
Cycloprodigiosin hydrochloride, a H+/Cl- symporter, induces apoptosis in human colon cancer cell lines in vitro. Oncology reports 20010101
Role of nitric oxide in human gastric cancer cells treated with 5-fluorouracil. Oncology reports 20010101
Cryopreservation of artificial cartilage: viability and functional examination after thawing. Cells, tissues, organs 20010101
In vitro establishment of cis-diammine-dichloroplatinum(II) resistant lung cancer cell line and modulation of apoptotic gene expression as a mechanism of resistant phenotype. Lung cancer (Amsterdam, Netherlands) 20010101
Cytotoxicity of aflatoxin B1 and its chemically synthesised epoxide derivative on the A549 human epithelioid lung cell line. Mycopathologia 20010101
A new sesquiterpene lactone from Tsoongiodendron odorum Chun. Journal of Asian natural products research 20010101
An in vitro study of the structure-activity relationships of sulfated polysaccharide from brown algae to its antioxidant effect. Journal of Asian natural products research 20010101
Paraquat-induced membrane dysfunction in pulmonary microvascular endothelial cells. Pharmacology & toxicology 20000301
Specific inhibition of influenza virus RNA polymerase and nucleoprotein gene expression by liposomally encapsulated antisense phosphorothioate oligonucleotides in MDCK cells. Antiviral chemistry & chemotherapy 19980501
Inhibitory effects of podophyllotoxin derivatives on herpes simplex virus replication. Antiviral chemistry & chemotherapy 19980501
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