Home Other Building Blocks 2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol

2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol

CAS No.:
23288-49-5
Catalog Number:
AG002MSJ
Molecular Formula:
C31H48O2S2
Molecular Weight:
516.8416
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$25
- +
25g
98%
In Stock USA
United States
$65
- +
100g
98%
In Stock USA
United States
$197
- +
500g
98%
In Stock USA
United States
$525
- +
Product Description
Catalog Number:
AG002MSJ
Chemical Name:
2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol
CAS Number:
23288-49-5
Molecular Formula:
C31H48O2S2
Molecular Weight:
516.8416
MDL Number:
MFCD00079281
IUPAC Name:
2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol
InChI:
InChI=1S/C31H48O2S2/c1-27(2,3)21-15-19(16-22(25(21)32)28(4,5)6)34-31(13,14)35-20-17-23(29(7,8)9)26(33)24(18-20)30(10,11)12/h15-18,32-33H,1-14H3
InChI Key:
FYPMFJGVHOHGLL-UHFFFAOYSA-N
SMILES:
CC(Sc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(Sc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)C
EC Number:
245-560-9
UNII:
P3CTH044XJ
Properties
Complexity:
583  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
516.31g/mol
Formal Charge:
0
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
516.843g/mol
Monoisotopic Mass:
516.31g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
91.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
11.3  
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[Preclinical and clinical studies of the efficacy of Panavir in therapy for tick-borne encephalitis]. Voprosy virusologii 20090101
The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials. BMJ (Clinical research ed.) 20090101
[Coronary artery bypass graft in adolescent suffering from homozygous familial hypercholesterolemia resistant to probucol therapy]. Le Mali medical 20090101
[Effect of Panavir on Herpes simplex virus types 1 and 2 proteins synthesis in cell culture]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101
Anti-atherosclerotic molecules targeting oxidative stress and inflammation. Current pharmaceutical design 20090101
[Protective activity of panavir in experimental rabies infection]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101
[A case of type 2 diabetes mellitus associated with familial hypercholesterolemia confirming the improvement of blood glucose control by colestimide]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20090101
Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. European journal of pharmacology 20081228
Risk factors for developing osteonecrosis after prophylaxis in steroid-treated rabbits. The Journal of rheumatology 20081201
Long-term probucol treatment prevents secondary cardiovascular events: a cohort study of patients with heterozygous familial hypercholesterolemia in Japan. Journal of atherosclerosis and thrombosis 20081201
A uniqe antilipidemic drug--probucol. Journal of atherosclerosis and thrombosis 20081201
[Effect of xiongshao capsule on lipid metabolism and platelet aggregation in experimental atherosclerosis rabbits]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20081201
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry 20081113
LXR-induced reverse cholesterol transport in human airway smooth muscle is mediated exclusively by ABCA1. American journal of physiology. Lung cellular and molecular physiology 20081101
Probucol markedly reduces HDL phospholipids and elevated prebeta1-HDL without delayed conversion into alpha-migrating HDL: putative role of angiopoietin-like protein 3 in probucol-induced HDL remodeling. Atherosclerosis 20081001
N-acetylcysteine protects against renal injury following bilateral ureteral obstruction. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
[Effects of Xiongshao capsule on the proliferation of vascular smooth muscle cells in rabbits with atherosclerosis]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20081001
Evaluation of biomarkers for cardiotoxicity of anthracyclin-based chemotherapy. Journal of cancer research and clinical oncology 20080901
Chylomicrons in disease-future challenges Invited keynote address. Atherosclerosis. Supplements 20080901
Lipid lowering effect of antioxidant alpha-lipoic Acid in experimental atherosclerosis. Journal of clinical biochemistry and nutrition 20080901
Preparation, characterization and optimization of probucol self-emulsified drug delivery system to enhance solubility and dissolution. Die Pharmazie 20080901
Effect of simvastatin on steroid-induced osteonecrosis evidenced by the serum lipid level and hepatic cytochrome P4503A in a rabbit model. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20080901
Novel indoline-based acyl-CoA:cholesterol acyltransferase inhibitor with antiperoxidative activity: improvement of physicochemical properties and biological activities by introduction of carboxylic acid. Journal of medicinal chemistry 20080814
Liver histology changes in nonalcoholic steatohepatitis after one year of treatment with probucol. Digestive diseases and sciences 20080801
In vitro-in vivo correlations of self-emulsifying drug delivery systems combining the dynamic lipolysis model and neuro-fuzzy networks. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080801
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. Pediatric nephrology (Berlin, Germany) 20080801
In situ mouse carotid perfusion model: glucose and cholesterol transport in the eye and brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080801
Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit. Cardiovascular drugs and therapy 20080801
Synergistic efficacy of concurrent treatment with cilostazol and probucol on the suppression of reactive oxygen species and inflammatory markers in cultured human coronary artery endothelial cells. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20080801
Antiatherogenic effects of cilostazol and probucol alone, and in combination in low density lipoprotein receptor-deficient mice fed with a high fat diet. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080701
Development of novel antiatherogenic biaryls: design, synthesis, and reactivity. Journal of medicinal chemistry 20080612
Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601
Morphology and surface States of colloidal probucol nanoparticles evaluated by atomic force microscopy. Chemical & pharmaceutical bulletin 20080601
[Advance in the study of compounds inducing the expression of heme oxygenase-1]. Yao xue xue bao = Acta pharmaceutica Sinica 20080601
Novel cardiac therapies and innocent by standers. Lancet (London, England) 20080524
Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial. Lancet (London, England) 20080524
[Influence of oxidative stress on atrial myocardium pathohistological and ultrastructural changes in atrial fibrillation: experiment with dogs]. Zhonghua yi xue za zhi 20080408
Formation mechanism of colloidal nanoparticles obtained from probucol/PVP/SDS ternary ground mixture. International journal of pharmaceutics 20080320
Effects of the antioxidant succinobucol (AGI-1067) on human atherosclerosis in a randomized clinical trial. Atherosclerosis 20080301
Expression and biological activity of ABCA1 in alveolar epithelial cells. American journal of respiratory cell and molecular biology 20080301
In vivo assessment of oral administration of probucol nanoparticles in rats. Biological & pharmaceutical bulletin 20080201
Effect of the anti-oxidant probucol on soluble thrombomodulin (sTM) in hypercholesterolemic rabbits. International journal of cardiology 20080111
Does membrane fatty acid composition modulate mitochondrial functions and their thermal sensitivities? Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080101
Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. Bioorganic & medicinal chemistry letters 20080101
RNAi for treating hepatitis B viral infection. Pharmaceutical research 20080101
Anti-atherosclerotic and anti-diabetic properties of probucol and related compounds. Redox report : communications in free radical research 20080101
[Effects of Xiongshao capsule on blood vessel collagenase gene expression in experimental rabbits with arterial restenosis]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080101
Viability of developing CETP inhibitors. Cardiovascular therapeutics 20080101
Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30. Pharmaceutical development and technology 20080101
Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice. PloS one 20080101
[Investigation of antiviral properties of new formulations of Panavir in the treatment of experimental herpes virus infection in mice]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101
Pharmacologic induction of heme oxygenase-1. Antioxidants & redox signaling 20071201
Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis. Free radical biology & medicine 20071201
Clinical trials update from the European Society of Cardiology Congress in Vienna, 2007: PROSPECT, EVEREST, ARISE, ALOFT, FINESSE, Prague-8, CARESS in MI and ACUITY. Cardiovascular drugs and therapy 20071201
hERG channel trafficking: novel targets in drug-induced long QT syndrome. Biochemical Society transactions 20071101
Relationship between free-radical lipid oxidation and efficiency of coronary angioplasty in coronary patients. Bulletin of experimental biology and medicine 20071101
[Adverse effects of lipid-lowering medications]. Nihon rinsho. Japanese journal of clinical medicine 20071028
Probucol modulates iron nitrilotriacetate (Fe-NTA)-dependent renal carcinogenesis and hyperproliferative response: diminution of oxidative stress. Molecular and cellular biochemistry 20071001
Combined pantethine and probucol therapy for Japanese patients with non-alcoholic steatohepatitis. Hepatology research : the official journal of the Japan Society of Hepatology 20071001
Modeling gastrointestinal drug absorption requires more in vivo biopharmaceutical data: experience from in vivo dissolution and permeability studies in humans. Current drug metabolism 20071001
Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents. Bioorganic & medicinal chemistry 20070915
Probucol mediates vascular remodeling after percutaneous transluminal angioplasty via down-regulation of the ERK1/2 signaling pathway. European journal of pharmacology 20070910
Pharmacologic approaches to restenosis prevention. The American journal of cardiology 20070903
Glucose fluctuation on the progression of diabetic macroangiopathy--new findings from monocyte adhesion to endothelial cells. Diabetes research and clinical practice 20070901
Bioassay-guided fractionation of antifertility components of castorbean (Ricinus communis L.) seed extracts. Natural product research 20070901
Probucol does not inhibit myeloperoxidase-dependent low-density lipoprotein oxidation as a potent protective effect in atherosclerosis. Journal of cardiovascular pharmacology 20070901
Phase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND.182-185. Current oncology (Toronto, Ont.) 20070801
Assessment of lipoprotein profiles study (ALPS) and antioxidant activity in healthy subjects treated with AGI-1067. Journal of clinical lipidology 20070801
[Probucol]. Nihon rinsho. Japanese journal of clinical medicine 20070728
[Drug-induced hypolipoproteinemia]. Nihon rinsho. Japanese journal of clinical medicine 20070728
Beneficial synergistic effects of concurrent treatment with cilostazol and probucol against focal cerebral ischemic injury in rats. Brain research 20070709
Oxidation of chylomicron remnant-like particles inhibits their uptake by THP-1 macrophages by apolipoprotein E-dependent processes. Biochimica et biophysica acta 20070701
Probucol therapy overcomes the reproductive defect in CTP: phosphocholine cytidylyltransferase beta2 knockout mice. Biochimica et biophysica acta 20070701
AGI-1067, a novel vascular protectant, anti-inflammatory drug and mild antiplatelet agent for treatment of atherosclerosis. Expert review of cardiovascular therapy 20070701
Serum cardiac markers in patients with acute myocardial infarction: oxidative stress, C-reactive protein and N-terminal probrain natriuretic Peptide. Journal of clinical biochemistry and nutrition 20070701
The MeOH extract of Pleurospermum kamtschaticum and its active component buddlejasaponin (IV) inhibits intrinsic and extrinsic hyperlipidemia and hypercholesterolemia in the rat. Journal of ethnopharmacology 20070613
Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicin-induced cardiotoxicity. British journal of cancer 20070604
Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes. The Journal of pharmacology and experimental therapeutics 20070601
Mechanisms involved in chylomicron remnant lipid uptake by macrophages. Biochemical Society transactions 20070601
[Animal models for steroid-induced osteonecrosis]. Clinical calcium 20070601
Probucol [4,4'-[(1-methylethylidene)bis(thio)]bis-[2,6-bis(1,1-dimethylethyl)phenol]] inhibits compensatory remodeling and promotes lumen loss associated with atherosclerosis in apolipoprotein E-deficient mice. The Journal of pharmacology and experimental therapeutics 20070501
Follicular development and expression of the messenger ribonucleic acid for the inhibin/activin subunits in two genetic lines of turkey hens that differ in total egg production. Poultry science 20070501
Cloning and expression of human haptoglobin subunits in Escherichia coli: delineation of a major antioxidant domain. Protein expression and purification 20070401
Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds. Journal of pharmaceutical sciences 20070401
Do statins reduce blood pressure?: a meta-analysis of randomized, controlled trials. Hypertension (Dallas, Tex. : 1979) 20070401
Effects of acetylcysteine and probucol on contrast medium-induced depression of intrinsic renal glutathione peroxidase activity in diabetic rats. Archives of medical research 20070401
Vascular cell adhesion molecule-1: a viable therapeutic target for atherosclerosis? International journal of clinical practice 20070401
[Research and developmental strategy of anti-dyslipidemic agents]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070401
Effect on carotid atherosclerosis of probucol plus levofloxacin for Chlamydia pneumoniae infection. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20070401
Oral treatment with probucol in a pharmacological dose has no beneficial effects on mortality in chronic ischemic heart failure after large myocardial infarction in rats. European journal of pharmacology 20070308
Antioxidant nature of bovine milk beta-lactoglobulin. Journal of dairy science 20070201
Anti-apoptotic effects of probucol are associated with downregulation of Daxx expression in THP-1 macrophage. Cardiovascular drugs and therapy 20070201
Effect of probucol on HDL metabolism and class B type I scavenger receptor (SR-BI) expression in the liver of hypercholesterolemic rabbits. International journal of cardiology 20070131
American Heart Association - Scientific Sessions 2006. Cell therapies for ischemic tissues and treatments for lipid metabolism disorders. IDrugs : the investigational drugs journal 20070101
Higher circulating 4-hydroxynonenal-protein thioether adducts correlate with more severe diastolic dysfunction in spontaneously hypertensive rats. Redox report : communications in free radical research 20070101
Probucol promotes endogenous antioxidant reserve and confers protection against reperfusion injury. Canadian journal of physiology and pharmacology 20070101
Inhibition of lipid peroxidation induced by hydroxyprogesterone caproate by some conventional antioxidants in goat liver homogenates. Acta poloniae pharmaceutica 20070101
Are HIV positive patients resistant to statin therapy? Lipids in health and disease 20070101
Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects. Lipids in health and disease 20070101
[Panavir, as a broad spectrum antiviral agent]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101
Probucol inhibits in-stent thrombosis and neointimal hyperplasia by promoting re-endothelialization. Atherosclerosis 20061201
Anti-inflammatory effects of different drugs/agents with antioxidant property on endothelial expression of adhesion molecules. Cardiovascular & hematological disorders drug targets 20061201
Comparative effects of pitavastatin and probucol on oxidative stress, Cu/Zn superoxide dismutase, PPAR-gamma, and aortic stiffness in hypercholesterolemia. American journal of physiology. Heart and circulatory physiology 20061101
Molecular interaction among probucol/PVP/SDS multicomponent system investigated by solid-state NMR. Pharmaceutical research 20061101
Role of probucol in inhibiting intimal hyperplasia after coronary stent implantation: a randomized study. American heart journal 20061101
Application of 18F-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061101
Combined effect of probucol and insulin on renal damage in diabetic rats fed a high cholesterol diet. European journal of pharmacology 20061024
[Can antioxidants prevent atherosclerosis?]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 20061001
Antioxidants suppress plasma levels of lectinlike oxidized low-density lipoprotein receptor-ligands and reduce atherosclerosis in watanabe heritable hyperlipidemic rabbits. Journal of cardiovascular pharmacology 20061001
Human urotensin-II potentiates the mitogenic effect of mildly oxidized low-density lipoprotein on vascular smooth muscle cells: comparison with other vasoactive agents and hydrogen peroxide. Hypertension research : official journal of the Japanese Society of Hypertension 20061001
Dietary phytosterols reduce probucol-induced atherogenesis in apo E-KO mice. Atherosclerosis 20060901
The in vitro effects of a novel vascular protectant, AGI-1067, on platelet aggregation and major receptor expression in subjects with multiple risk factors for vascular disease. Journal of cardiovascular pharmacology and therapeutics 20060901
Tripterine inhibits the expression of adhesion molecules in activated endothelial cells. Journal of leukocyte biology 20060801
Probucol decreases asymmetrical dimethylarginine level by alternation of protein arginine methyltransferase I and dimethylarginine dimethylaminohydrolase activity. Cardiovascular drugs and therapy 20060801
Both hepatitis C virus and Chlamydia pneumoniae infection are related to the progression of carotid atherosclerosis in patients undergoing lipid lowering therapy. Fukuoka igaku zasshi = Hukuoka acta medica 20060801
Protective effect of calceolarioside on adriamycin-induced cardiomyocyte toxicity. European journal of pharmacology 20060710
Importance of acyl-coenzyme A:cholesterol acyltransferase 1/2 dual inhibition for anti-atherosclerotic potency of pactimibe. European journal of pharmacology 20060701
[Beneficial effects of probucol on endothelial function in patients with acute coronary syndrome]. Zhonghua xin xue guan bing za zhi 20060701
Induction of adiponectin in skeletal muscle of type 2 diabetic mice: In vivo and in vitro studies. Diabetologia 20060601
CETP levels rather than polymorphisms as markers of coronary risk: healthy athlete with high HDL-C and coronary disease--effectiveness of probucol. Atherosclerosis 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Are small biotechs still underselling themselves? Nature biotechnology 20060501
[Effects of xuezhikang capsules on vascular endothelial function and redox status in patients with coronary heart disease]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060501
Phenolic compounds from the roots of Lindera fruticosa. Journal of natural products 20060501
Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy. Journal of cardiovascular pharmacology 20060501
[Effect of probucol and losartan on growth factors after balloon angioplasty in rabbits]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20060401
LDL-antioxidant pterocarpans from roots of Glycine max (L.) Merr. Journal of agricultural and food chemistry 20060322
Relative contributions of ABCA1 and SR-BI to cholesterol efflux to serum from fibroblasts and macrophages. Arteriosclerosis, thrombosis, and vascular biology 20060301
Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progressive mesangioproliferative glomerulonephritis in the rat. Journal of the American Society of Nephrology : JASN 20060301
Determination of DPPH free radical scavenging activity by reversed-phase HPLC: a sensitive screening method for polyherbal formulations. Journal of pharmaceutical and biomedical analysis 20060213
Probucol delays progression of diabetic nephropathy. Diabetes research and clinical practice 20060201
Cyclic diarylheptanoids inhibit cell-mediated low-density lipoprotein oxidation. Natural product research 20060201
Antioxidants: the good, the bad and the ugly. The Canadian journal of cardiology 20060201
Probucol and atorvastatin decrease urinary 8-hydroxy-2'-deoxyguanosine in patients with diabetes and hypercholesterolemia. Journal of atherosclerosis and thrombosis 20060201
Drug nanoparticle formation from drug/HPMC/SDS ternary ground mixtures. Die Pharmazie 20060201
Review article: Drug therapy for non-alcoholic fatty liver disease. Alimentary pharmacology & therapeutics 20060115
Macrophage apolipoprotein E reduces atherosclerosis and prevents premature death in apolipoprotein E and scavenger receptor-class BI double-knockout mice. Arteriosclerosis, thrombosis, and vascular biology 20060101
Cyclic diarylheptanoids inhibit cell mediated low-density lipoprotein oxidation. Natural product research 20060101
Chemical structure-dependent gene expression of proteasome subunits via regulation of the antioxidant response element. Free radical research 20060101
AGI-1067: a novel vascular protectant for prevention of restenosis. The Annals of pharmacotherapy 20060101
Probucol up-regulates paraoxonase 1 expression in hepatocytes of hypercholesterolemic rabbits. Journal of cardiovascular pharmacology 20060101
Evaluation of the rabbit Purkinje fibre assay as an in vitro tool for assessing the risk of drug-induced torsades de pointes in humans. Drug safety 20060101
Effect of probucol on elderly hypercholesterolemic patients in the FAST study. Fukuoka igaku zasshi = Hukuoka acta medica 20060101
Different inflammatory response and oxidative stress in neointimal hyperplasia after balloon angioplasty and stent implantation in cholesterol-fed rabbits. Pathology, research and practice 20060101
Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis. Annual review of nutrition 20060101
Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens. BMC neuroscience 20060101
[Interaction between dinitrosyl iron complexes and intermediate products of oxidative stress]. Biofizika 20060101
Effects of alpha tocopherol and probucol supplements on allergen-induced airway inflammation and hyperresponsiveness in a mouse model of allergic asthma. International archives of allergy and immunology 20060101
The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids in health and disease 20060101
Bifidobacterium infantis strains with and without a combination of oligofructose and inulin (OFI) attenuate inflammation in DSS-induced colitis in rats. BMC gastroenterology 20060101
Pretreatment with probucol attenuates cardiomyocyte apoptosis in a rabbit model of ischemia/reperfusion. Scandinavian journal of clinical and laboratory investigation 20060101
[The role of epsilon 2/epsilon 3/epsilon 4 polymorphism of the apolipoprotein E gene in the development of dislipoproteinemia and its influence on the efficacy of the hypolipidemic therapy]. TSitologiia i genetika 20060101
Dietary probucol preserves endothelium-dependent relaxation of arteriovenous fistula in hypercholesterolemic rabbits. Chang Gung medical journal 20060101
Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials. Chinese medicine 20060101
Inhibition of vascular remodelling in a porcine coronary injury model by herbal extract XS0601. Chinese medicine 20060101
[Effect of Panavir on influenza A virus reproduction]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans. The Journal of biological chemistry 20051230
Design, synthesis, and evaluation of pharmacological properties of cinnamic derivatives as antiatherogenic agents. Journal of medicinal chemistry 20051229
[Oxidative stress and cardiovascular diseases]. Deutsche medizinische Wochenschrift (1946) 20051216
Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20051201
Influence of amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats. Journal of nutritional science and vitaminology 20051201
Reduction of oxidative stress and apoptosis in hyperlipidemic rabbits by ellagic acid. The Journal of nutritional biochemistry 20051101
Probucol enhances the expression of human hepatic scavenger receptor class B type I, possibly through a species-specific mechanism. Arteriosclerosis, thrombosis, and vascular biology 20051101
In vitro and in vivo effects of probucol on hydrolysis of asymmetric dimethyl L-arginine and vasospasm in primates. Journal of neurosurgery 20051001
Ten-year follow-up of familial hypercholesterolemia patients after intensive cholesterol-lowering therapy. International heart journal 20050901
A case of familial hypercholesterolemia; secession from LDL-apheresis by the drug treatment with potent statin and resin. The Tokai journal of experimental and clinical medicine 20050901
Processes involved in the site-specific effect of probucol on atherosclerosis in apolipoprotein E gene knockout mice. Arteriosclerosis, thrombosis, and vascular biology 20050801
Enzymatic characterization of lipid-based drug delivery systems. International journal of pharmaceutics 20050725
Cholesterol levels and statin use in patients with coronary heart disease treated in primary care settings. Preventing chronic disease 20050701
[Long QT syndrome]. Nihon rinsho. Japanese journal of clinical medicine 20050701
Study of antiparkinsonic activity of panavir on a model of Parkinson syndrome induced by systemic administration of MPTP to outbred rats and C57Bl/6 mice. Bulletin of experimental biology and medicine 20050701
Are we over oxidized? Oxidative stress, cardiovascular disease, and the future of intervention studies with antioxidants. Vascular health and risk management 20050601
AGIX-4207 [2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid], a novel antioxidant and anti-inflammatory compound: cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression. The Journal of pharmacology and experimental therapeutics 20050501
Effort angina in a middle-aged woman with abnormally high levels of serum high-density lipoprotein cholesterol: a case of cholesteryl-ester transfer protein deficiency. Circulation journal : official journal of the Japanese Circulation Society 20050501
Reduction of oxidative stress and atherosclerosis in hyperlipidemic rabbits by Dioscorea rhizome. Canadian journal of physiology and pharmacology 20050501
Probucol protects against hypochlorite-induced endothelial dysfunction: identification of a novel pathway of probucol oxidation to a biologically active intermediate. The Journal of biological chemistry 20050422
Combined effect of probucol and insulin on cataracts of diabetic rats fed a high cholesterol diet. European journal of pharmacology 20050418
Probucol attenuates oxidative stress and energy decline in isoproterenol-induced heart failure in rat. Pharmacological research 20050401
Anthocyanins increase low-density lipoprotein and plasma cholesterol and do not reduce atherosclerosis in Watanabe Heritable Hyperlipidemic rabbits. Molecular nutrition & food research 20050401
Involvement of mitogen-activated protein kinases in adriamycin-induced cardiomyopathy. American journal of physiology. Heart and circulatory physiology 20050401
Suppressive effects of cacao liquor polyphenols (CLP) on LDL oxidation and the development of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbits. Atherosclerosis 20050401
Na+/H+ exchange inhibition and antioxidants lack additive protective effects after reperfusion injury in the working heterotopic rat heart isograft. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
Apolipoprotein E, cholesterol transport and synthesis in sporadic Alzheimer's disease. Neurobiology of aging 20050301
Antioxidants and atherosclerosis: emerging drug therapies. Current atherosclerosis reports 20050201
Low daily dose of antioxidant probucol decreases incidence and severity of restenosis after transluminal coronary balloon angioplasty. Bulletin of experimental biology and medicine 20050201
On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway. Journal of lipid research 20050101
Effect of anti-oxidant (carvedilol and probucol) loaded stents in a porcine coronary restenosis model. Circulation journal : official journal of the Japanese Circulation Society 20050101
Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release. BMC neuroscience 20050101
Protection of cortical cells by equine estrogens against glutamate-induced excitotoxicity is mediated through a calcium independent mechanism. BMC neuroscience 20050101
Danshen inhibits oxysterol-induced endothelial cell apoptosis in vivo. Journal of atherosclerosis and thrombosis 20050101
Oxidative stress and pancreatic beta-cell dysfunction. American journal of therapeutics 20050101
Vitamin E supplementation alters HDL-cholesterol concentration and paraoxonase activity in rabbits fed high-cholesterol diet: comparison with probucol. Journal of biochemical and molecular toxicology 20050101
Inhibition of lipoprotein lipid oxidation. Handbook of experimental pharmacology 20050101
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases. Journal of medicinal chemistry 20041202
Probucol inhibits ABCA1-mediated cellular lipid efflux. Arteriosclerosis, thrombosis, and vascular biology 20041201
Effects of probucol versus aspirin and versus brachytherapy on restenosis after femoropopliteal angioplasty: the PAB randomized multicenter trial. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20041201
Antioxidant activities of a new lignan and a neolignan from Saururus chinensis. Bioorganic & medicinal chemistry letters 20041115
Carvedilol inhibits tumor necrosis factor-alpha-induced endothelial transcription factor activation, adhesion molecule expression, and adhesiveness to human mononuclear cells. Arteriosclerosis, thrombosis, and vascular biology 20041101
Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20041101
HMG CoA reductase inhibitors (statins) for dialysis patients. The Cochrane database of systematic reviews 20041018
3,4,5,6-Tetrahydroxyxanthone prevents vascular endothelial cell apoptosis induced by high glucose. Naunyn-Schmiedeberg's archives of pharmacology 20041001
Mixed connective tissue disease associated with antineutrophil cytoplasmic antibodies against proteinase-3 and systemic atherosclerosis: a case report. Clinical rheumatology 20041001
Combined effects of an anticoagulant and a lipid-lowering agent on the prevention of steroid-induced osteonecrosis in rabbits. Arthritis and rheumatism 20041001
Concurrent therapies that protect against doxorubicin-induced cardiomyopathy. Clinical journal of oncology nursing 20041001
Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1. Circulation 20040928
Synthesis of cinnamic acid derivatives and their inhibitory effects on LDL-oxidation, acyl-CoA:cholesterol acyltransferase-1 and -2 activity, and decrease of HDL-particle size. Bioorganic & medicinal chemistry letters 20040920
[NO and atherosclerosis]. Nihon rinsho. Japanese journal of clinical medicine 20040901
[Study of diagnostic criteria of intima-media thickening and effects of drugs on peripheral arteries]. Zhonghua yi xue za zhi 20040802
Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG. Clinical science (London, England : 1979) 20040801
Inhibitory effects of multi-substituted benzylidenethiazolidine-2,4-diones on LDL oxidation. Bioorganic & medicinal chemistry 20040801
Antioxidant role of human haptoglobin. Proteomics 20040801
Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases. Acta pharmacologica Sinica 20040801
Probucol inactivates ABCA1 in the plasma membrane with respect to its mediation of apolipoprotein binding and high density lipoprotein assembly and to its proteolytic degradation. The Journal of biological chemistry 20040716
Oligodendrocytes are susceptible to apoptotic cell death induced by prion protein-derived peptides. Glia 20040701
Novel 3,5-diaryl pyrazolines and pyrazole as low-density lipoprotein (LDL) oxidation inhibitor. Bioorganic & medicinal chemistry letters 20040607
Probucol and ticlopidine: effect on platelet and monocyte activation markers in hyperlipidemic patients with and without type 2 diabetes. Atherosclerosis 20040601
Pravastatin has an additional depressor effect in patients undergoing long-term treatment with antihypertensive drugs. American journal of hypertension 20040601
Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells. European journal of biochemistry 20040601
Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice. Pharmaceutical research 20040601
Acteoside protects endothelial cells against free radical-induced oxidative stress. The Journal of pharmacy and pharmacology 20040601
New drugs to improve transplant outcomes. Transplantation 20040515
Carvedilol inhibits basal and stimulated ACE production in human endothelial cells. Journal of cardiovascular pharmacology 20040501
Effect of probucol on the oral bioavailability of cyclosporine A. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040501
Long-term treatment with probucol improves endothelial function in patients with coronary artery disease. Hypertension research : official journal of the Japanese Society of Hypertension 20040501
Liquid chromatographic method for the simultaneous determination of different lipid-soluble antioxidants in human plasma and low-density lipoproteins. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040425
Regulation of mitochondrial transcription factor A expression by high glucose. Annals of the New York Academy of Sciences 20040401
[Effect of xiongshao capsule on vascular remodeling in rabbit with experimental atherosclerosis]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040401
Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein. The Journal of biological chemistry 20040312
Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: a novel antioxidant and anti-inflammatory agent. The Journal of pharmacology and experimental therapeutics 20040301
Redox processes underlying the vascular repair reaction. World journal of surgery 20040301
Effect of probucol on neointimal thickening in a stent porcine restenosis model. Japanese heart journal 20040301
Protective mechanisms against peptide and protein peroxides generated by singlet oxygen. Free radical biology & medicine 20040215
Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway. The Journal of biological chemistry 20040206
Potent antioxidant properties of 4-hydroxyl-propranolol. The Journal of pharmacology and experimental therapeutics 20040101
Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc. Journal of pharmacological and toxicological methods 20040101
Cardioprotective effects of carvedilol on acute autoimmune myocarditis: anti-inflammatory effects associated with antioxidant property. American journal of physiology. Heart and circulatory physiology 20040101
Alpha-tocopherol preserves endothelial cell migration in the presence of cell-oxidized low-density lipoprotein by inhibiting changes in cell membrane fluidity. Journal of vascular surgery 20040101
Effects of probucol on renal function and urinary protein excretion in spontaneously hypercholesterolemic rats fed a normal or high cholesterol diet. Kidney & blood pressure research 20040101
Plant sterols: factors affecting their efficacy and safety as functional food ingredients. Lipids in health and disease 20040101
Role of antioxidant enzymes and antioxidant compound probucol in antiradical protection of pancreatic beta-cells during alloxan-induced diabetes. Bulletin of experimental biology and medicine 20040101
Effect of Lovastatin on lipid peroxidation and total antioxidant concentrations in hemodialysis patients. Lipids in health and disease 20040101
Amelioration of the beta-cell dysfunction in diabetic APA hamsters by antioxidants and AGE inhibitor treatments. Diabetes/metabolism research and reviews 20040101
Management of hyperlipidaemia associated with heart transplantation. Drugs 20040101
Exploring effects of different antioxidants on dexamethasone-induced lipid peroxidation using common laboratory markers. Acta poloniae pharmaceutica 20040101
Ciprofibrate therapy in patients with hypertriglyceridemia and low high density lipoprotein (HDL)-cholesterol: greater reduction of non-HDL cholesterol in subjects with excess body weight (The CIPROAMLAT study). Cardiovascular diabetology 20040101
Probucol as a potent inhibitor of oxygen radical-induced lipid peroxidation and DNA damage: in vitro studies. Redox report : communications in free radical research 20040101
Probucol, a hypocholesterolemic agent, prevents the development of uterine adenomyosis induced by pituitary grafting in mice. Anticancer research 20040101
Oxidized low-density lipoprotein and 15-deoxy-delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells. American journal of physiology. Heart and circulatory physiology 20031201
Pharmacologic prevention of both restenosis and atherosclerosis progression: AGI-1067, probucol, statins, folic acid and other therapies. Current opinion in lipidology 20031201
Cytotoxic cellular cholesterol is selectively removed by apoA-I via ABCA1. Atherosclerosis 20031201
Association of Chlamydia pneumoniae antibody with the cholesterol-lowering effect of statins. Atherosclerosis 20031201
Homozygous familial hypercholesterolaemia: development of xanthogranuloma in a boy at puberty under long-term low-density lipoprotein apheresis and drug therapy. The British journal of dermatology 20031201
Induction of NAD(P)H:quinone reductase by probucol: a possible mechanism for protection against chemical carcinogenesis and toxicity. Pharmacology & toxicology 20031201
Direct vascular effects of HR780, a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Clinical and experimental pharmacology & physiology 20031201
Dietary prevention of post-angioplasty restenosis. From illusion and disillusion to pragmatism. Nutrition, metabolism, and cardiovascular diseases : NMCD 20031201
New aspects in probucol cardioprotection against doxorubicin-induced cardiotoxicity. Cancer chemotherapy and pharmacology 20031101
Experimental and clinical studies show that the probucol derivative AGI-1067 prevents vascular growth. Expert opinion on investigational drugs 20031101
Modulation of HDL metabolism by probucol in complete cholesteryl ester transfer protein deficiency. Atherosclerosis 20031101
Probucol restores the defective leukocyte-endothelial interaction in experimental diabetes. European journal of pharmacology 20031008
Probucol decreases mevalonate pyrophosphate decarboxylase in the rat liver. Biological & pharmaceutical bulletin 20031001
Cytochrome P450-mediated oxidative damage of nuclear membrane proteins and its prevention by vitamin C. Indian journal of biochemistry & biophysics 20031001
Ginkgo biloba extract inhibits tumor necrosis factor-alpha-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells. Arteriosclerosis, thrombosis, and vascular biology 20030901
Foreign body-type multinucleated giant cell formation is potently induced by alpha-tocopherol and prevented by the diacylglycerol kinase inhibitor R59022. The American journal of pathology 20030901
Optimizing probucol administration to preserve left ventricular compliance after reperfusion injury in the heterotopic rat heart isograft. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030901
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Novel 3-O-acyl mesquitol analogues as free-radical scavengers and enzyme inhibitors: synthesis, biological evaluation and structure-activity relationship. Bioorganic & medicinal chemistry letters 20030818
Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats. Journal of the American Society of Nephrology : JASN 20030801
Effect of antioxidant probucol on cell-mediated LDL oxidation in vitro and in vivo. Bulletin of experimental biology and medicine 20030801
Interrelation between compensation of carbohydrate metabolism and severity of manifestations of oxidative stress in type II diabetes mellitus. Bulletin of experimental biology and medicine 20030801
Design and synthesis of 4,6-di-tert-butyl-2,3-dihydro-5-benzofuranols as a novel series of antiatherogenic antioxidants. Journal of medicinal chemistry 20030703
NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy. Journal of molecular and cellular cardiology 20030701
Mechanisms of glomerular immune injury: effects of antioxidant treatment. Journal of the American Society of Nephrology : JASN 20030701
Signal jammer. An academic experiment leads to a new class of drug for attacking heart disease. Scientific American 20030701
Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins. Molecular and cellular biochemistry 20030701
Protective effects of probucol treatment on pancreatic beta-cell function of SZ-induced diabetic APA hamsters. Experimental animals 20030701
AGI-1067: a multifunctional phenolic antioxidant, lipid modulator, anti-inflammatory and antiatherosclerotic agent. The Journal of pharmacology and experimental therapeutics 20030601
Oxidized low-density lipoprotein inhibits endothelium-dependent vasodilation by an antioxidant-sensitive, lysophosphatidylcholine-independent mechanism. Journal of cardiovascular pharmacology 20030601
Effects of candesartan and probucol on restenosis after coronary stenting: results of insight of stent intimal hyperplasia inhibition by new angiotensin II receptor antagonist (ISHIN) trial. Circulation journal : official journal of the Japanese Circulation Society 20030601
A water-extract of the Korean traditional formulation Geiji-Bokryung-Hwan reduces atherosclerosis and hypercholesteremia in cholesterol-fed rabbits. International immunopharmacology 20030501
Probucol promotes functional reendothelialization in balloon-injured rabbit aortas. Circulation 20030422
Antioxidants, statins, and atherosclerosis. Journal of the American College of Cardiology 20030402
Probucol in the treatment of non-alcoholic steatohepatitis: a double-blind randomized controlled study. Journal of hepatology 20030401
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NF-kappa B activation in endothelial cells treated with oxidized high-density lipoprotein. Biochemical and biophysical research communications 20030328
Amlodipine inhibits doxorubicin-induced apoptosis in neonatal rat cardiac myocytes. Journal of the American College of Cardiology 20030305
Optimal management of nonalcoholic fatty liver/steatohepatitis. Journal of clinical gastroenterology 20030301
Probucol in the treatment of nonalcoholic steatohepatitis: an open-labeled study. Journal of clinical gastroenterology 20030301
Differential effects of catalase on apoptosis induction in human promonocytic cells. Relationships with heat-shock protein expression. Molecular pharmacology 20030301
Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. Trends in molecular medicine 20030301
Chemistry and pharmacology of vascular protectants: a novel approach to the treatment of atherosclerosis and coronary artery disease. The American journal of cardiology 20030206
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Effects of AGI-1067 and probucol after percutaneous coronary interventions. Circulation 20030204
Apoptotic neuronal cell death induced by the non-fibrillar amyloid-beta peptide proceeds through an early reactive oxygen species-dependent cytoskeleton perturbation. The Journal of biological chemistry 20030131
Hypercholesterolemia is a prerequisite for puromycin inducible damage in mouse kidney. Kidney international 20030101
Resolution of typical lipoprotein glomerulopathy by intensive lipid-lowering therapy. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030101
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Ascorbic acid augments cytotoxicity induced by oxidized low-density lipoprotein. Journal of atherosclerosis and thrombosis 20030101
Alpha-tocopherol modulates the low density lipoprotein receptor of human HepG2 cells. Nutrition journal 20030101
The antiatherogenic effect of DiNAC: experimental findings supporting immunomodulation as a new treatment for atherosclerosis related diseases. Cardiovascular drug reviews 20030101
Potential role of the interaction between equine estrogens, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in the prevention of coronary heart and neurodegenerative diseases in postmenopausal women. Lipids in health and disease 20030101
Effects of probucol on endothelial damage by 5-fluorouracil. Acta oncologica (Stockholm, Sweden) 20030101
The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease. Neuroscience 20030101
Protection against acute adriamycin-induced cardiotoxicity by garlic: role of endogenous antioxidants and inhibition of TNF-alpha expression. BMC pharmacology 20030101
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[Effect of probucol on the blood concentration of cyclosporin A in patients with nephrotic syndrome: a case study with a microemulsion formulation (Neoral)]. Nihon Jinzo Gakkai shi 20021201
Nitric oxide releasing morpholine derivatives as hypolipidemic and antioxidant agents. Journal of medicinal chemistry 20021121
Application of quantitative competitive polymerase chain reaction for measurements of mRNA from antioxidative enzymes in the diabetic rat retina and kidney. Metabolism: clinical and experimental 20021001
Antioxidative effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001
The effect of probucol on atherosclerosis in streptozotocin-induced diabetic-hyperlipidemic APA hamsters in different stages of atherosclerosis. Experimental animals 20021001
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Evaluation of pharmacokinetic interaction between cyclosporin A and probucol in rats. Pharmaceutical research 20020901
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Comparison of the effects of alpha-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits. Atherosclerosis 20020801
Effect of probucol on cytochrome P450 activities in human liver microsomes. Biological & pharmaceutical bulletin 20020801
Effects of probucol in hyperlipidemic rabbit liver: a preliminary ultrastructural study. Okajimas folia anatomica Japonica 20020801
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Probucol preserves pancreatic beta-cell function through reduction of oxidative stress in type 2 diabetes. Diabetes research and clinical practice 20020701
DNA damage and the effect of antioxidants in streptozotocin-treated mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020701
Potential emerging therapeutic strategies to prevent restenosis in the peripheral vasculature. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020701
Intensification of free radical oxidation of low-density lipoproteins in the plasma of patients with ischemic heart disease receiving beta-hydroxy-beta-methylglutaryl-coenzyme A reductase inhibitor cerivastatin and inhibition of low-density lipoprotein peroxidation with antioxidant probucol. Bulletin of experimental biology and medicine 20020701
Antioxidative activity of green tea polyphenol in cholesterol-fed rats. Journal of agricultural and food chemistry 20020605
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Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis. Circulation 20020514
Inhibitory effect of a novel water-soluble vitamin E derivative on atherosclerosis in rabbits. Atherosclerosis 20020501
Stilbazulenyl nitrone (STAZN): a nitronyl-substituted hydrocarbon with the potency of classical phenolic chain-breaking antioxidants. Journal of the American Chemical Society 20020501
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2,3,4-Trimethyl-5,7-dihydroxy-2,3-dihydrobenzofuran, a novel antioxidant, from Penicillium citrinum F5. Journal of natural products 20020501
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Comparison of antioxidant effects of naringin and probucol in cholesterol-fed rabbits. Clinica chimica acta; international journal of clinical chemistry 20020301
Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level. British journal of pharmacology 20020301
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Improved post-myocardial infarction survival with probucol in rats: effects on left ventricular function, morphology, cardiac oxidative stress and cytokine expression. Journal of the American College of Cardiology 20020102
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Probucol and liver efficiency during chemically-induced hepatocarcinogenesis. Anticancer research 20020101
Evaluation of probucol as suppressor of ceftizoxime induced lipid peroxidation. Acta poloniae pharmaceutica 20020101
The protective effects of tetrahydrocurcumin on oxidative stress in cholesterol-fed rabbits. Journal of atherosclerosis and thrombosis 20020101
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Cyclodextrins in the treatment of a mouse model of Niemann-Pick C disease. Life sciences 20011130
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A dynamic in vitro lipolysis model. II: Evaluation of the model. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20011001
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Retinal glial cell immunoreactivity and neuronal cell changes in rats with STZ-induced diabetes. Current eye research 20011001
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Antioxidative properties of probucol estimated by the reactivity with superoxide and by electrochemical oxidation. Chemical & pharmaceutical bulletin 20010801
Angiotensin-converting enzyme inhibitors and probucol suppress the time-dependent increase in urinary Type IV collagen excretion of Type II diabetes mellitus patients with early diabetic nephropathy. Clinical nephrology 20010801
Vascular dysfunction induced by AGE is mediated by VEGF via mechanisms involving reactive oxygen species, guanylate cyclase, and protein kinase C. Microcirculation (New York, N.Y. : 1994) 20010801
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Apheresis technology for prevention and regression of atherosclerosis. Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis 20010801
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Characterization of simple and reproducible vascular stenosis model in hypercholesterolemic hamsters. Lipids 20010501
Inhibition of purified pig and human liver retinyl ester hydrolase by pharmacologic agents. Lipids 20010501
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Treatment of hyperlipidemia in HIV-infected patients. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010401
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Selective inhibition by probucol of vascular cell adhesion molecule-1 (VCAM-1) expression in human vascular endothelial cells. Atherosclerosis 20010301
Effect of probucol in lecithin-cholesterol acyltransferase-deficient mice: inhibition of 2 independent cellular cholesterol-releasing pathways in vivo. Arteriosclerosis, thrombosis, and vascular biology 20010301
Protection against nitrofurantoin-induced oxidative stress by coelenterazine analogues and their oxidation products in rat hepatocytes. Free radical research 20010301
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The effect of pharmacological doses of different antioxidants on oxidation parameters and atherogenesis in hyperlipidaemic rabbits. Atherosclerosis 20010201
Effects of probucol on rat carotid artery responses to balloon catheter injury. Atherosclerosis 20010201
Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes. The Journal of pharmacy and pharmacology 20010201
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Probucol decreases total body fat loss in VX2-carcinoma-induced cachectic rabbits. Oncology reports 20010101
Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women. Menopause (New York, N.Y.) 20010101
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Structural changes in oxidised low-density lipoproteins and of the effect of the anti-atherosclerotic drug probucol observed by synchrotron X-ray and neutron solution scattering. European journal of biochemistry 19890801
Treatment of heterozygous familial hypercholesterolemia with lipid-lowering drugs. Arteriosclerosis (Dallas, Tex.) 19890101
Probucol-induced QT prolongation and torsades de pointes. Japanese journal of medicine 19890101
Effects of some hypolipidemic agents on biochemical values and hepatic peroxisomal enzymes in rats: comparison of probucol, CGA, KCD-232, MLM-160, AL-369 and clinofibrate with clofibrate. Journal of pharmacobio-dynamics 19870301
Effect of probucol on plasma lipids and lipoproteins in type IIb hyperlipoproteinemia. Atherosclerosis 19801101
Adrenergaically mediated ventricular fibrillation in probucol-treated dogs: roles of alpha and beta adrenergic receptors. Pacing and clinical electrophysiology : PACE 19790701
Sensitization to epinephrine-induced ventricular fibrillation produced by probucol in dogs. Toxicology and applied pharmacology 19730401
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