2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol
Title | Journal |
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Why are most phospholipidosis inducers also hERG blockers? | Archives of toxicology 20171201 |
Beneficial effects of TQRF and TQ nano- and conventional emulsions on memory deficit, lipid peroxidation, total antioxidant status, antioxidants genes expression and soluble Aβ levels in high fat-cholesterol diet-induced rats. | Chemico-biological interactions 20170925 |
Activation of the Nrf2/ARE signaling pathway by probucol contributes to inhibiting inflammation and neuronal apoptosis after spinal cord injury. | Oncotarget 20170808 |
Methylmercury-induced developmental toxicity is associated with oxidative stress and cofilin phosphorylation. Cellular and human studies. | Neurotoxicology 20170301 |
Ginsenoside Rd attenuates Aβ25-35-induced oxidative stress and apoptosis in primary cultured hippocampal neurons. | Chemico-biological interactions 20150905 |
Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells. | Pharmacological research 20131001 |
Does methylmercury-induced hypercholesterolemia play a causal role in its neurotoxicity and cardiovascular disease? | Toxicological sciences : an official journal of the Society of Toxicology 20121201 |
Improved intestinal absorption of a poorly water-soluble oral drug using mannitol microparticles containing a nanosolid drug dispersion. | Journal of pharmaceutical sciences 20121101 |
Development of solid self-emulsifying drug delivery system (SEDDS) I: use of poloxamer 188 as both solidifying and emulsifying agent for lipids. | Pharmaceutical research 20121001 |
A randomized, open-label, multicentre study to evaluate plasma atherosclerotic biomarkers in patients with type 2 diabetes mellitus and arteriosclerosis obliterans when treated with Probucol and Cilostazol. | Journal of geriatric cardiology : JGC 20120901 |
Nanoparticulation of probucol, a poorly water-soluble drug, using a novel wet-milling process to improve in vitro dissolution and in vivo oral absorption. | Drug development and industrial pharmacy 20120801 |
Benzophenones and xanthones from Garcinia cantleyana var. cantleyana and their inhibitory activities on human low-density lipoprotein oxidation and platelet aggregation. | Phytochemistry 20120801 |
Development of a novel model of hypertriglyceridemic acute pancreatitis in hamsters: protective effects of probucol. | Pancreas 20120801 |
Nano-pulverization of poorly water soluble compounds with low melting points by a rotation/revolution pulverizer. | Die Pharmazie 20120801 |
Effects of physicochemical forms of phenazepam and Panavir on their action at ultra-low doses. | Bulletin of experimental biology and medicine 20120801 |
Combined effect of atorvastatin and probucol on plasma cystatin C levels and severity of coronary lesion in patients with borderline coronary lesion. | Chinese medical journal 20120701 |
[Effects of three different treatments on atherosclerosis and adipose in rats]. | Zhonghua yi xue za zhi 20120619 |
Ginkgo biloba extract (GbE) enhances the anti-atherogenic effect of cilostazol by inhibiting ROS generation. | Experimental & molecular medicine 20120531 |
Structural evaluation of probucol nanoparticles in water by atomic force microscopy. | International journal of pharmaceutics 20120510 |
Crystallization, spectral, crystallographical, and thermoanalytical studies of succinobucol polymorphism. | Journal of pharmaceutical sciences 20120501 |
Development of a probucol-releasing antithrombogenic drug eluting stent. | Journal of biomedical materials research. Part B, Applied biomaterials 20120501 |
ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma. | Journal of lipid research 20120501 |
[Effect of probucol on serum malondialdehyde and superoxide dismutase in patients with primary hypertension]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20120501 |
Involvement of glomerular renin-angiotensin system (RAS) activation in the development and progression of glomerular injury. | Clinical and experimental nephrology 20120401 |
Chronic probucol treatment decreases the slow component of the delayed-rectifier potassium current in CHO cells transfected with KCNQ1 and KCNE1: a novel mechanism of QT prolongation. | Journal of cardiovascular pharmacology 20120401 |
Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro. | Brain research bulletin 20120310 |
Probucol: can we step forward in atherosclerosis prevention with an old drug? | Atherosclerosis 20120301 |
Succinobucol induces apoptosis in vascular smooth muscle cells. | Free radical biology & medicine 20120301 |
Anti-hypercholesterolemic and anti-atherosclerotic effects of polarized-light therapy in rabbits fed a high-cholesterol diet. | Laboratory animal research 20120301 |
Molecular-level characterization of probucol nanocrystal in water by in situ solid-state NMR spectroscopy. | International journal of pharmaceutics 20120227 |
Probucol and atorvastatin in combination protect rat brains in MCAO model: upregulating Peroxiredoxin2, Foxo3a and Nrf2 expression. | Neuroscience letters 20120216 |
Comparison of high-resolution ultrasonic resonator technology and Raman spectroscopy as novel process analytical tools for drug quantification in self-emulsifying drug delivery systems. | Journal of pharmaceutical and biomedical analysis 20120205 |
Probucol therapy improves long-term (>10-year) survival after complete revascularization: a propensity analysis. | Atherosclerosis 20120201 |
Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid β peptide in mice. | Experimental neurology 20120201 |
Impact of short-duration administration of N-acetylcysteine, probucol and ascorbic acid on contrast-induced cytotoxicity. | Journal of nephrology 20120101 |
Probucol suppresses enterocytic accumulation of amyloid-β induced by saturated fat and cholesterol feeding. | Lipids 20120101 |
The oxidative state of chylomicron remnants influences their modulation of human monocyte activation. | International journal of vascular medicine 20120101 |
Modulation of fibrosis in systemic sclerosis by nitric oxide and antioxidants. | Cardiology research and practice 20120101 |
Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation. | International journal of nanomedicine 20120101 |
Effects of inhibiting CoQ10 biosynthesis with 4-nitrobenzoate in human fibroblasts. | PloS one 20120101 |
ABCG2- and ABCG4-mediated efflux of amyloid-β peptide 1-40 at the mouse blood-brain barrier. | Journal of Alzheimer's disease : JAD 20120101 |
Systematic Review of Chinese Herbal Medicines for Preventing in-Stent Coronary Restenosis after Percutaneous Coronary Intervention. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies. | Nutrition & metabolism 20120101 |
Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics. | International journal of Alzheimer's disease 20120101 |
Study of the effects of total flavonoids of Astragalus on atherosclerosis formation and potential mechanisms. | Oxidative medicine and cellular longevity 20120101 |
Low-dose fluvastatin prevents the functional alterations of endothelium induced by short-term cholesterol feeding in rabbit carotid artery. | TheScientificWorldJournal 20120101 |
Novel Aspects of Nonfasting Lipemia in relation to Vascular Biology. | International journal of vascular medicine 20120101 |
Detrimental effects of non-functional spermatozoa on the freezability of functional spermatozoa from boar ejaculate. | PloS one 20120101 |
Heme oxygenase, inflammation, and fibrosis: the good, the bad, and the ugly? | Frontiers in pharmacology 20120101 |
Chitosan-Pluronic nanoparticles as oral delivery of anticancer gemcitabine: preparation and in vitro study. | International journal of nanomedicine 20120101 |
Quercetin and epigallocatechin gallate induce in vitro a dose-dependent stiffening and hyperpolarizing effect on the cell membrane of human mononuclear blood cells. | International journal of molecular sciences 20120101 |
Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing. | International journal of vascular medicine 20120101 |
Urinary markers of glomerular injury in diabetic nephropathy. | International journal of nephrology 20120101 |
Oxidative stress and heart failure in altered thyroid States. | TheScientificWorldJournal 20120101 |
LDL-apheresis: technical and clinical aspects. | TheScientificWorldJournal 20120101 |
The antioxidant 3H-1,2-dithiole-3-thione potentiates advanced glycation end-product-induced oxidative stress in SH-SY5Y cells. | Experimental diabetes research 20120101 |
Progress in pathogenesis of proteinuria. | International journal of nephrology 20120101 |
Cardioprotective effect of sodium ferulate in diabetic rats. | International journal of medical sciences 20120101 |
Effect of probucol on antioxidant properties of HDL in patients with heterozygous familial hypercholesterolemia. | Journal of atherosclerosis and thrombosis 20120101 |
Epithelial-to-mesenchymal transdifferentiation of renal tubular epithelial cell mediated by oxidative stress and intervention effect of probucol in diabetic nephropathy rats. | Renal failure 20120101 |
Clinical spectrum and therapy of non-alcoholic steatohepatitis. | Digestive diseases (Basel, Switzerland) 20120101 |
Redox pioneer: professor Roland Stocker. | Antioxidants & redox signaling 20111215 |
In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish. | The Journal of clinical investigation 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
N-acetylcysteine for Prevention of Contrast-Induced Nephropathy: A Narrative Review. | Korean circulation journal 20111201 |
Succinobucol's new coat--conjugation with steroids to alter its drug effect and bioavailability. | Molecules (Basel, Switzerland) 20111110 |
Chance and serendipity in science: two examples from my own career. | The Journal of biological chemistry 20111104 |
Direct evidence of abca1-mediated efflux of cholesterol at the mouse blood-brain barrier. | Molecular and cellular biochemistry 20111101 |
Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein. | Atherosclerosis 20111101 |
Pharmacokinetics and tolerability of probucol after multiple oral administrations in healthy volunteers. | International journal of clinical pharmacology and therapeutics 20111101 |
The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis. | Korean circulation journal 20111101 |
[Efficacy observation of combination of Lumbrukinase Capsule and Probucol Tablet in treating cerebral infarction patients' unstable atheromatous plaque of the carotid artery]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20111101 |
Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport. | Circulation 20110920 |
Probucol attenuates inflammation and increases stability of vulnerable atherosclerotic plaques in rabbits. | The Tohoku journal of experimental medicine 20110901 |
Novel benzoxazine and benzothiazine derivatives as multifunctional antihyperlipidemic agents. | Journal of medicinal chemistry 20110811 |
Polymer-free sirolimus- and probucol-eluting versus new generation zotarolimus-eluting stents in coronary artery disease: the Intracoronary Stenting and Angiographic Results: Test Efficacy of Sirolimus- and Probucol-Eluting versus Zotarolimus-eluting Stents (ISAR-TEST 5) trial. | Circulation 20110802 |
Combinatorial effect of probucol and cilostazol in focal ischemic mice with hypercholesterolemia. | The Journal of pharmacology and experimental therapeutics 20110801 |
Possible role for the thioredoxin system in the protective effects of probucol in the pancreatic islets of diabetic rats. | Clinical and experimental pharmacology & physiology 20110801 |
Markers of redox imbalance in the blood of hypertensive patients of a community in Northeastern Brazil. | Arquivos brasileiros de cardiologia 20110801 |
Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice. | EMBO molecular medicine 20110701 |
Antioxidant effects of Citrus aurantifolia (Christm) juice and peel extract on LDL oxidation. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110701 |
The cardioprotective role of probucol against anthracycline and trastuzumab-mediated cardiotoxicity. | Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20110601 |
Effect of probucol on vascular remodeling due to atherosclerosis in rabbits: an intravascular ultrasound study. | Chinese medical journal 20110601 |
Involvement of caveolin in probucol-induced reduction in hERG plasma-membrane expression. | Molecular pharmacology 20110501 |
An eight-week trial investigating the efficacy and tolerability of atorvastatin for children and adolescents with heterozygous familial hypercholesterolemia. | Pediatric cardiology 20110401 |
[Stability of probucol-polyvinylpyrrolidone solid dispersion systems]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110401 |
A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110318 |
Haemoglobin-induced oxidative stress is associated with both endogenous peroxidase activity and H2O2 generation from polyunsaturated fatty acids. | Free radical research 20110301 |
Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low density lipoprotein receptor. | Biochimica et biophysica acta 20110301 |
Free cholesterol alters macrophage morphology and mobility by an ABCA1 dependent mechanism. | Atherosclerosis 20110301 |
Two-year clinical outcome after carvedilol-loaded stent implantation in patients with coronary artery disease. | The Korean journal of internal medicine 20110301 |
Salvianolic acid B inhibits low-density lipoprotein oxidation and neointimal hyperplasia in endothelium-denuded hypercholesterolaemic rabbits. | Journal of the science of food and agriculture 20110115 |
Dietary fatty acids and oxidative stress in the heart mitochondria. | Mitochondrion 20110101 |
Evaluation of Effectiveness of Vitamins C and E on Prevention of Renal Scar due to Pyelonephritis in Rat. | Advances in urology 20110101 |
[Novel therapy for atherosclerosis and inflammatory vascular disease]. | Nihon rinsho. Japanese journal of clinical medicine 20110101 |
Study design and rationale of 'Synergistic effect of combination therapy with cilostazol and ProbUcol on plaque stabilization and lesion REgression (SECURE)' study: a double-blind randomised controlled multicenter clinical trial. | Trials 20110101 |
Antioxidative protection of dietary bilberry, chokeberry and Lactobacillus plantarum HEAL19 in mice subjected to intestinal oxidative stress by ischemia-reperfusion. | BMC complementary and alternative medicine 20110101 |
Effects of grapefruit, grapefruit juice and water preloads on energy balance, weight loss, body composition, and cardiometabolic risk in free-living obese adults. | Nutrition & metabolism 20110101 |
Cilostazol improves symptomatic intracranial artery stenosis - Evaluation of cerebral blood flow with single photon emission computed tomography. | Surgical neurology international 20110101 |
Epithelial-to-mesenchymal transdifferentiation of peritoneal mesothelial cells mediated by oxidative stress in peritoneal fibrosis rats. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20110101 |
Nanotechnology for the treatment of coronary in stent restenosis: a clinical perspective. | Vascular cell 20110101 |
Roles of the WHHL rabbit in translational research on hypercholesterolemia and cardiovascular diseases. | Journal of biomedicine & biotechnology 20110101 |
Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets. | Diabetologia 20110101 |
Function and comorbidities of apolipoprotein e in Alzheimer's disease. | International journal of Alzheimer's disease 20110101 |
Oxidative stress and redox modulation potential in type 1 diabetes. | Clinical & developmental immunology 20110101 |
Malignancy-associated dyslipidemia. | The open cardiovascular medicine journal 20110101 |
Reversal of redox-dependent inhibition of diacylglycerol kinase by antioxidants in mesangial cells exposed to high glucose. | Molecular medicine reports 20110101 |
Anti-Atherogenic Activity of Ethanolic Fraction of Terminalia arjuna Bark on Hypercholesterolemic Rabbits. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Oxidative Stress and Inflammation in Heart Disease: Do Antioxidants Have a Role in Treatment and/or Prevention? | International journal of inflammation 20110101 |
Liposomal Antioxidants for Protection against Oxidant-Induced Damage. | Journal of toxicology 20110101 |
Probucol attenuates oxidative stress, energy starvation, and nitric acid production following transient forebrain ischemia in the rat hippocampus. | Oxidative medicine and cellular longevity 20110101 |
Effect of plant sterols on the lipid profile of patients with hypercholesterolaemia. Randomised, experimental study. | BMC complementary and alternative medicine 20110101 |
Combined effects of p-coumaric acid and naringenin against doxorubicin-induced cardiotoxicity in rats. | Pharmacognosy research 20110101 |
Probucol alleviates atherosclerosis and improves high density lipoprotein function. | Lipids in health and disease 20110101 |
Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts. | The Journal of toxicological sciences 20110101 |
Bioactive constituents and medicinal importance of genus Alnus. | Pharmacognosy reviews 20110101 |
[Panavir in combined treatment of chronic cystitis with hyperplastic changes in urinary bladder mucosa]. | Urologiia (Moscow, Russia : 1999) 20110101 |
No consensus on definition criteria for stroke registry common data elements. | Cerebrovascular diseases extra 20110101 |
Statins: past and present. | Heart views : the official journal of the Gulf Heart Association 20110101 |
Interplay between heme oxygenase-1 and the multifunctional transcription factor yin yang 1 in the inhibition of intimal hyperplasia. | Circulation research 20101210 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Plasma lipoproteins are required for both basal and stress-induced adrenal glucocorticoid synthesis and protection against endotoxemia in mice. | American journal of physiology. Endocrinology and metabolism 20101201 |
Antioxidant interventions as novel preventive strategies for postoperative atrial fibrillation. | International journal of cardiology 20101105 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Design of more potent squalene synthase inhibitors with multiple activities. | Bioorganic & medicinal chemistry 20101101 |
A beverage containing fermented black soybean ameliorates ferric nitrilotriacetate-induced renal oxidative damage in rats. | Journal of clinical biochemistry and nutrition 20101101 |
Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis. | Current cardiology reviews 20101101 |
Probucol and succinobucol in atrial fibrillation: pros and cons. | International journal of cardiology 20101008 |
Transglycosylated stevia and hesperidin as pharmaceutical excipients: dramatic improvement in drug dissolution and bioavailability. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20101001 |
Chlorogenic acid attenuates adhesion molecules upregulation in IL-1beta-treated endothelial cells. | European journal of nutrition 20100801 |
Impact of statin treatment on the clinical fate of heterozygous familial hypercholesterolemia. | Journal of atherosclerosis and thrombosis 20100730 |
AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets. | Molecular and cellular endocrinology 20100729 |
Effects of atorvastatin versus probucol on low-density lipoprotein subtype distribution and renal function in hyperlipidemic patients with nondiabetic nephropathy. | Renal failure 20100701 |
Overexpression of steroidogenic acute regulatory protein increases macrophage cholesterol efflux to apolipoprotein AI. | Cardiovascular research 20100601 |
Post-prandial lipid metabolism, lipid-modulating agents and cerebrovascular integrity: implications for dementia risk. | Atherosclerosis. Supplements 20100601 |
[Front line of oxidized lipoproteins: role of oxidized lipoproteins in atherogenesis and cardiovascular disease risk]. | Rinsho byori. The Japanese journal of clinical pathology 20100601 |
ATP-binding cassette transporter A1 is involved in hepatic alpha-tocopherol secretion. | The Journal of nutritional biochemistry 20100501 |
Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro. | British journal of cancer 20100427 |
The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages. | Arteriosclerosis, thrombosis, and vascular biology 20100401 |
Effects of grape pomace on the antioxidant defense system in diet-induced hypercholesterolemic rabbits. | Nutrition research and practice 20100401 |
Cross-platform expression microarray performance in a mouse model of mitochondrial disease therapy. | Molecular genetics and metabolism 20100301 |
Probucol and antioxidant vitamins rescue ischemia-induced neovascularization in mice exposed to cigarette smoke: potential role of endothelial progenitor cells. | Atherosclerosis 20100201 |
Homogeneous nanoparticles to enhance the efficiency of a hydrophobic drug, antihyperlipidemic probucol, characterized by solid-state NMR. | Molecular pharmaceutics 20100201 |
Vitamin E prevents steroid-induced osteonecrosis in rabbits. | Acta orthopaedica 20100201 |
Antioxidant therapy reverses impaired graft healing in hypercholesterolemic rabbits. | Journal of vascular surgery 20100101 |
Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits. | International journal of molecular sciences 20100101 |
Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis. | Mediators of inflammation 20100101 |
Janus kinase 2/signal transducers and activators of transcription signal inhibition regulates protective effects of probucol on mesangial cells treated with high glucose. | Biological & pharmaceutical bulletin 20100101 |
Tocopherol induced angiogenesis in placental vascular network in late pregnant ewes. | Reproductive biology and endocrinology : RB&E 20100101 |
Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment. | Nutrition journal 20100101 |
Variability of serum oxidative stress biomarkers relative to biochemical data and clinical parameters of glaucoma patients. | Molecular vision 20100101 |
Impact of medical therapy on atheroma volume measured by different cardiovascular imaging modalities. | Cardiology research and practice 20100101 |
Methylguanidine cytotoxicity on HK-2 cells and protective effect of antioxidants against MG-induced apoptosis in renal proximal tubular cells in vitro. | Renal failure 20100101 |
[Immunocorrecting therapy of chronic bacterial prostatitis]. | Urologiia (Moscow, Russia : 1999) 20100101 |
Effects of fenofibrate on lipid profiles, cholesterol ester transfer activity, and in-stent intimal hyperplasia in patients after elective coronary stenting. | Lipids in health and disease 20100101 |
High-density lipoprotein therapeutics and cardiovascular prevention. | Journal of clinical lipidology 20100101 |
Analyses of copy number variation of GK rat reveal new putative type 2 diabetes susceptibility loci. | PloS one 20100101 |
Low high-density lipoprotein cholesterol: current status and future strategies for management. | Vascular health and risk management 20100101 |
Use of hamster as a model to study diet-induced atherosclerosis. | Nutrition & metabolism 20100101 |
Probucol attenuates cyclophosphamide-induced oxidative apoptosis, p53 and Bax signal expression in rat cardiac tissues. | Oxidative medicine and cellular longevity 20100101 |
Effect of salvianolic acid B and paeonol on blood lipid metabolism and hemorrheology in myocardial ischemia rabbits induced by pituitruin. | International journal of molecular sciences 20100101 |
Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment. | The open cardiovascular medicine journal 20100101 |
Metabolic clues: novel directives for broad treatment strategies. | Oxidative medicine and cellular longevity 20100101 |
Update on the role of candesartan in the optimal management of hypertension and cardiovascular risk reduction. | Integrated blood pressure control 20100101 |
Development, characterization and solubility study of solid dispersions of azithromycin dihydrate by solvent evaporation method. | Journal of advanced pharmaceutical technology & research 20100101 |
Development, characterization and solubility study of solid dispersions of Cefuroxime Axetil by the solvent evaporation method. | Journal of advanced pharmaceutical technology & research 20100101 |
Macrophage scavenger receptor A mediates adhesion to apolipoproteins A-I and E. | Biochemistry 20091222 |
Improvement of nephrotic syndrome by intensive lipid-lowering therapy in a patient with lipoprotein glomerulopathy. | Clinical and experimental nephrology 20091201 |
Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells. | Toxicological sciences : an official journal of the Society of Toxicology 20091201 |
Stimulation of stellate cells by injured acinar cells: a model of acute pancreatitis induced by alcohol and fat (VLDL). | American journal of physiology. Gastrointestinal and liver physiology 20091201 |
Protective effects of lycopene against H2O2-induced oxidative injury and apoptosis in human endothelial cells. | Cardiovascular drugs and therapy 20091201 |
Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1. | Biochemistry 20091124 |
Where are we with probucol: a new life for an old drug? | Atherosclerosis 20091101 |
Pharmacological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis. | Journal of lipid research 20091101 |
Ascorbic acid and tetrahydrobiopterin potentiate the EDHF phenomenon by generating hydrogen peroxide. | Cardiovascular research 20091101 |
Pharmacologic therapy of non-alcoholic steatohepatitis. | Clinics in liver disease 20091101 |
Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration. | Diabetes care 20091101 |
Enhanced bioavailability of probucol following the administration of solid dispersion systems of probucol-polyvinylpyrrolidone in rabbits. | Biological & pharmaceutical bulletin 20091101 |
Impact of chronic anticholesterol therapy on development of microvascular rarefaction in the metabolic syndrome. | Microcirculation (New York, N.Y. : 1994) 20091101 |
Pro-atherogenic effects of probucol in apo E-KO mice may be mediated through alterations in immune system: Parallel alterations in gene expression in the aorta and liver. | Atherosclerosis 20091001 |
Heme oxygenase-1 increases endothelial progenitor cells. | Arteriosclerosis, thrombosis, and vascular biology 20091001 |
A concise description of cardioprotective strategies in doxorubicin-induced cardiotoxicity. | Canadian journal of physiology and pharmacology 20091001 |
Potential interactions between cilostazol and probucol: a two-part, single-dose, open-label study in healthy Korean male volunteers. | Clinical therapeutics 20091001 |
[Effects of atorvastatin, alone and in combination with probucol on endothelial function in patients with acute coronary syndrome]. | Zhonghua xin xue guan bing za zhi 20091001 |
Computer diagnosis in cardiology: oxidative stress hypothesis. | North American journal of medical sciences 20091001 |
Malformed mdx myofibers have normal cytoskeletal architecture yet altered EC coupling and stress-induced Ca2+ signaling. | American journal of physiology. Cell physiology 20090901 |
Antiphospholipid antibodies in systemic sclerosis: a double oxidative hit? | Clinical rheumatology 20090801 |
Antioxidant probucol attenuates myocardial oxidative stress and collagen expressions in post-myocardial infarction rats. | Journal of cardiovascular pharmacology 20090801 |
Iatrogenic QT Abnormalities and Fatal Arrhythmias: Mechanisms and Clinical Significance. | Current cardiology reviews 20090801 |
[Effects of probucol, aspirin and atorvastatin combination therapy upon atherosclerosis]. | Zhonghua yi xue za zhi 20090728 |
Nanoparticle formation from probucol/PVP/sodium alkyl sulfate co-ground mixture. | International journal of pharmaceutics 20090706 |
Differential roles of nitric oxide synthase isozymes in cardiotoxicity and mortality following chronic doxorubicin treatment in mice. | Naunyn-Schmiedeberg's archives of pharmacology 20090701 |
Neurogenic inflammation and cardiac dysfunction due to hypomagnesemia. | The American journal of the medical sciences 20090701 |
Influence of T-calcium channel blocker treatment on deterioration of renal function in chronic kidney disease. | Heart and vessels 20090701 |
Effects of N-acetyl-cysteine on endothelial function and inflammation in patients with type 2 diabetes mellitus. | Heart international 20090630 |
Effects of probucol on hepatic tumor necrosis factor-alpha, interleukin-6 and adiponectin receptor-2 expression in diabetic rats. | Journal of gastroenterology and hepatology 20090601 |
Cytotoxicity of 5-fluorouracil: Effect on endothelial differentiation via cell cycle inhibition in mouse embryonic stem cells. | Toxicology in vitro : an international journal published in association with BIBRA 20090601 |
Molecular mechanisms underlying the antiatherosclerotic and antidiabetic effects of probucol, succinobucol, and other probucol analogues. | Current opinion in lipidology 20090601 |
Suppression of anti-Candida activity of macrophages by a quorum-sensing molecule, farnesol, through induction of oxidative stress. | Microbiology and immunology 20090601 |
Selective thromboxane inhibition after vascular protectant AGI-1067: results of assessment of lipoprotein profiles (ALPS) biomarkers in vitro and in vivo substudy. | Journal of thrombosis and thrombolysis 20090501 |
Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review. | Journal of pediatric gastroenterology and nutrition 20090501 |
[Role of probucol in preventing contrast induced acute kidney injury after coronary interventional procedure: a randomized trial]. | Zhonghua xin xue guan bing za zhi 20090501 |
Probucol attenuates atrial structural remodeling in prolonged pacing-induced atrial fibrillation in dogs. | Biochemical and biophysical research communications 20090403 |
A polymer-free dual drug-eluting stent in patients with coronary artery disease: a randomized trial vs. polymer-based drug-eluting stents. | European heart journal 20090401 |
Succinobucol: review of the metabolic, antiplatelet and cardiovascular effects. | Expert opinion on investigational drugs 20090401 |
Chemotherapy induced cardiomyopathy: pathogenesis, monitoring and management. | Journal of clinical medicine research 20090401 |
Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1. | Circulation research 20090313 |
Role of probucol in preventing contrast-induced acute kidney injury after coronary interventional procedure. | The American journal of cardiology 20090215 |
The pre-clinical assessment of rapamycin-eluting, durable polymer-free stent coating concepts. | Biomaterials 20090201 |
Activation of hepatic lipase expression by oleic acid: possible involvement of USF1. | Nutrients 20090201 |
Probucol attenuates atrial autonomic remodeling in a canine model of atrial fibrillation produced by prolonged atrial pacing. | Chinese medical journal 20090105 |
Emerging role of FDG-PET/CT in assessing atherosclerosis in large arteries. | European journal of nuclear medicine and molecular imaging 20090101 |
Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis. | BMJ (Clinical research ed.) 20090101 |
Nanoparticle processing in the solid state dramatically increases the cell membrane permeation of a cholesterol-lowering drug, probucol. | Molecular pharmaceutics 20090101 |
Alpha-tocopherol: looking beyond an antioxidant. | Molecular vision 20090101 |
[Antiviral activity of panavir in experimental Measles virus infection in cell cultures]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101 |
[Preclinical and clinical studies of the efficacy of Panavir in therapy for tick-borne encephalitis]. | Voprosy virusologii 20090101 |
The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials. | BMJ (Clinical research ed.) 20090101 |
[Coronary artery bypass graft in adolescent suffering from homozygous familial hypercholesterolemia resistant to probucol therapy]. | Le Mali medical 20090101 |
[Effect of Panavir on Herpes simplex virus types 1 and 2 proteins synthesis in cell culture]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101 |
Anti-atherosclerotic molecules targeting oxidative stress and inflammation. | Current pharmaceutical design 20090101 |
[Protective activity of panavir in experimental rabies infection]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101 |
[A case of type 2 diabetes mellitus associated with familial hypercholesterolemia confirming the improvement of blood glucose control by colestimide]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20090101 |
Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. | European journal of pharmacology 20081228 |
Risk factors for developing osteonecrosis after prophylaxis in steroid-treated rabbits. | The Journal of rheumatology 20081201 |
Long-term probucol treatment prevents secondary cardiovascular events: a cohort study of patients with heterozygous familial hypercholesterolemia in Japan. | Journal of atherosclerosis and thrombosis 20081201 |
A uniqe antilipidemic drug--probucol. | Journal of atherosclerosis and thrombosis 20081201 |
[Effect of xiongshao capsule on lipid metabolism and platelet aggregation in experimental atherosclerosis rabbits]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20081201 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
LXR-induced reverse cholesterol transport in human airway smooth muscle is mediated exclusively by ABCA1. | American journal of physiology. Lung cellular and molecular physiology 20081101 |
Probucol markedly reduces HDL phospholipids and elevated prebeta1-HDL without delayed conversion into alpha-migrating HDL: putative role of angiopoietin-like protein 3 in probucol-induced HDL remodeling. | Atherosclerosis 20081001 |
N-acetylcysteine protects against renal injury following bilateral ureteral obstruction. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001 |
[Effects of Xiongshao capsule on the proliferation of vascular smooth muscle cells in rabbits with atherosclerosis]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20081001 |
Evaluation of biomarkers for cardiotoxicity of anthracyclin-based chemotherapy. | Journal of cancer research and clinical oncology 20080901 |
Chylomicrons in disease-future challenges Invited keynote address. | Atherosclerosis. Supplements 20080901 |
Lipid lowering effect of antioxidant alpha-lipoic Acid in experimental atherosclerosis. | Journal of clinical biochemistry and nutrition 20080901 |
Preparation, characterization and optimization of probucol self-emulsified drug delivery system to enhance solubility and dissolution. | Die Pharmazie 20080901 |
Effect of simvastatin on steroid-induced osteonecrosis evidenced by the serum lipid level and hepatic cytochrome P4503A in a rabbit model. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20080901 |
Novel indoline-based acyl-CoA:cholesterol acyltransferase inhibitor with antiperoxidative activity: improvement of physicochemical properties and biological activities by introduction of carboxylic acid. | Journal of medicinal chemistry 20080814 |
Liver histology changes in nonalcoholic steatohepatitis after one year of treatment with probucol. | Digestive diseases and sciences 20080801 |
In vitro-in vivo correlations of self-emulsifying drug delivery systems combining the dynamic lipolysis model and neuro-fuzzy networks. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080801 |
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. | Pediatric nephrology (Berlin, Germany) 20080801 |
In situ mouse carotid perfusion model: glucose and cholesterol transport in the eye and brain. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080801 |
Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit. | Cardiovascular drugs and therapy 20080801 |
Synergistic efficacy of concurrent treatment with cilostazol and probucol on the suppression of reactive oxygen species and inflammatory markers in cultured human coronary artery endothelial cells. | The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20080801 |
Antiatherogenic effects of cilostazol and probucol alone, and in combination in low density lipoprotein receptor-deficient mice fed with a high fat diet. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080701 |
Development of novel antiatherogenic biaryls: design, synthesis, and reactivity. | Journal of medicinal chemistry 20080612 |
Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601 |
Morphology and surface States of colloidal probucol nanoparticles evaluated by atomic force microscopy. | Chemical & pharmaceutical bulletin 20080601 |
[Advance in the study of compounds inducing the expression of heme oxygenase-1]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080601 |
Novel cardiac therapies and innocent by standers. | Lancet (London, England) 20080524 |
Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial. | Lancet (London, England) 20080524 |
[Influence of oxidative stress on atrial myocardium pathohistological and ultrastructural changes in atrial fibrillation: experiment with dogs]. | Zhonghua yi xue za zhi 20080408 |
Formation mechanism of colloidal nanoparticles obtained from probucol/PVP/SDS ternary ground mixture. | International journal of pharmaceutics 20080320 |
Effects of the antioxidant succinobucol (AGI-1067) on human atherosclerosis in a randomized clinical trial. | Atherosclerosis 20080301 |
Expression and biological activity of ABCA1 in alveolar epithelial cells. | American journal of respiratory cell and molecular biology 20080301 |
In vivo assessment of oral administration of probucol nanoparticles in rats. | Biological & pharmaceutical bulletin 20080201 |
Effect of the anti-oxidant probucol on soluble thrombomodulin (sTM) in hypercholesterolemic rabbits. | International journal of cardiology 20080111 |
Does membrane fatty acid composition modulate mitochondrial functions and their thermal sensitivities? | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080101 |
Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. | Bioorganic & medicinal chemistry letters 20080101 |
RNAi for treating hepatitis B viral infection. | Pharmaceutical research 20080101 |
Anti-atherosclerotic and anti-diabetic properties of probucol and related compounds. | Redox report : communications in free radical research 20080101 |
[Effects of Xiongshao capsule on blood vessel collagenase gene expression in experimental rabbits with arterial restenosis]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080101 |
Viability of developing CETP inhibitors. | Cardiovascular therapeutics 20080101 |
Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30. | Pharmaceutical development and technology 20080101 |
Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice. | PloS one 20080101 |
[Investigation of antiviral properties of new formulations of Panavir in the treatment of experimental herpes virus infection in mice]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101 |
Pharmacologic induction of heme oxygenase-1. | Antioxidants & redox signaling 20071201 |
Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis. | Free radical biology & medicine 20071201 |
Clinical trials update from the European Society of Cardiology Congress in Vienna, 2007: PROSPECT, EVEREST, ARISE, ALOFT, FINESSE, Prague-8, CARESS in MI and ACUITY. | Cardiovascular drugs and therapy 20071201 |
hERG channel trafficking: novel targets in drug-induced long QT syndrome. | Biochemical Society transactions 20071101 |
Relationship between free-radical lipid oxidation and efficiency of coronary angioplasty in coronary patients. | Bulletin of experimental biology and medicine 20071101 |
[Adverse effects of lipid-lowering medications]. | Nihon rinsho. Japanese journal of clinical medicine 20071028 |
Probucol modulates iron nitrilotriacetate (Fe-NTA)-dependent renal carcinogenesis and hyperproliferative response: diminution of oxidative stress. | Molecular and cellular biochemistry 20071001 |
Combined pantethine and probucol therapy for Japanese patients with non-alcoholic steatohepatitis. | Hepatology research : the official journal of the Japan Society of Hepatology 20071001 |
Modeling gastrointestinal drug absorption requires more in vivo biopharmaceutical data: experience from in vivo dissolution and permeability studies in humans. | Current drug metabolism 20071001 |
Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents. | Bioorganic & medicinal chemistry 20070915 |
Probucol mediates vascular remodeling after percutaneous transluminal angioplasty via down-regulation of the ERK1/2 signaling pathway. | European journal of pharmacology 20070910 |
Pharmacologic approaches to restenosis prevention. | The American journal of cardiology 20070903 |
Glucose fluctuation on the progression of diabetic macroangiopathy--new findings from monocyte adhesion to endothelial cells. | Diabetes research and clinical practice 20070901 |
Bioassay-guided fractionation of antifertility components of castorbean (Ricinus communis L.) seed extracts. | Natural product research 20070901 |
Probucol does not inhibit myeloperoxidase-dependent low-density lipoprotein oxidation as a potent protective effect in atherosclerosis. | Journal of cardiovascular pharmacology 20070901 |
Phase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND.182-185. | Current oncology (Toronto, Ont.) 20070801 |
Assessment of lipoprotein profiles study (ALPS) and antioxidant activity in healthy subjects treated with AGI-1067. | Journal of clinical lipidology 20070801 |
[Probucol]. | Nihon rinsho. Japanese journal of clinical medicine 20070728 |
[Drug-induced hypolipoproteinemia]. | Nihon rinsho. Japanese journal of clinical medicine 20070728 |
Beneficial synergistic effects of concurrent treatment with cilostazol and probucol against focal cerebral ischemic injury in rats. | Brain research 20070709 |
Oxidation of chylomicron remnant-like particles inhibits their uptake by THP-1 macrophages by apolipoprotein E-dependent processes. | Biochimica et biophysica acta 20070701 |
Probucol therapy overcomes the reproductive defect in CTP: phosphocholine cytidylyltransferase beta2 knockout mice. | Biochimica et biophysica acta 20070701 |
AGI-1067, a novel vascular protectant, anti-inflammatory drug and mild antiplatelet agent for treatment of atherosclerosis. | Expert review of cardiovascular therapy 20070701 |
Serum cardiac markers in patients with acute myocardial infarction: oxidative stress, C-reactive protein and N-terminal probrain natriuretic Peptide. | Journal of clinical biochemistry and nutrition 20070701 |
The MeOH extract of Pleurospermum kamtschaticum and its active component buddlejasaponin (IV) inhibits intrinsic and extrinsic hyperlipidemia and hypercholesterolemia in the rat. | Journal of ethnopharmacology 20070613 |
Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicin-induced cardiotoxicity. | British journal of cancer 20070604 |
Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes. | The Journal of pharmacology and experimental therapeutics 20070601 |
Mechanisms involved in chylomicron remnant lipid uptake by macrophages. | Biochemical Society transactions 20070601 |
[Animal models for steroid-induced osteonecrosis]. | Clinical calcium 20070601 |
Probucol [4,4'-[(1-methylethylidene)bis(thio)]bis-[2,6-bis(1,1-dimethylethyl)phenol]] inhibits compensatory remodeling and promotes lumen loss associated with atherosclerosis in apolipoprotein E-deficient mice. | The Journal of pharmacology and experimental therapeutics 20070501 |
Follicular development and expression of the messenger ribonucleic acid for the inhibin/activin subunits in two genetic lines of turkey hens that differ in total egg production. | Poultry science 20070501 |
Cloning and expression of human haptoglobin subunits in Escherichia coli: delineation of a major antioxidant domain. | Protein expression and purification 20070401 |
Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds. | Journal of pharmaceutical sciences 20070401 |
Do statins reduce blood pressure?: a meta-analysis of randomized, controlled trials. | Hypertension (Dallas, Tex. : 1979) 20070401 |
Effects of acetylcysteine and probucol on contrast medium-induced depression of intrinsic renal glutathione peroxidase activity in diabetic rats. | Archives of medical research 20070401 |
Vascular cell adhesion molecule-1: a viable therapeutic target for atherosclerosis? | International journal of clinical practice 20070401 |
[Research and developmental strategy of anti-dyslipidemic agents]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070401 |
Effect on carotid atherosclerosis of probucol plus levofloxacin for Chlamydia pneumoniae infection. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20070401 |
Oral treatment with probucol in a pharmacological dose has no beneficial effects on mortality in chronic ischemic heart failure after large myocardial infarction in rats. | European journal of pharmacology 20070308 |
Antioxidant nature of bovine milk beta-lactoglobulin. | Journal of dairy science 20070201 |
Anti-apoptotic effects of probucol are associated with downregulation of Daxx expression in THP-1 macrophage. | Cardiovascular drugs and therapy 20070201 |
Effect of probucol on HDL metabolism and class B type I scavenger receptor (SR-BI) expression in the liver of hypercholesterolemic rabbits. | International journal of cardiology 20070131 |
American Heart Association - Scientific Sessions 2006. Cell therapies for ischemic tissues and treatments for lipid metabolism disorders. | IDrugs : the investigational drugs journal 20070101 |
Higher circulating 4-hydroxynonenal-protein thioether adducts correlate with more severe diastolic dysfunction in spontaneously hypertensive rats. | Redox report : communications in free radical research 20070101 |
Probucol promotes endogenous antioxidant reserve and confers protection against reperfusion injury. | Canadian journal of physiology and pharmacology 20070101 |
Inhibition of lipid peroxidation induced by hydroxyprogesterone caproate by some conventional antioxidants in goat liver homogenates. | Acta poloniae pharmaceutica 20070101 |
Are HIV positive patients resistant to statin therapy? | Lipids in health and disease 20070101 |
Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects. | Lipids in health and disease 20070101 |
[Panavir, as a broad spectrum antiviral agent]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101 |
Probucol inhibits in-stent thrombosis and neointimal hyperplasia by promoting re-endothelialization. | Atherosclerosis 20061201 |
Anti-inflammatory effects of different drugs/agents with antioxidant property on endothelial expression of adhesion molecules. | Cardiovascular & hematological disorders drug targets 20061201 |
Comparative effects of pitavastatin and probucol on oxidative stress, Cu/Zn superoxide dismutase, PPAR-gamma, and aortic stiffness in hypercholesterolemia. | American journal of physiology. Heart and circulatory physiology 20061101 |
Molecular interaction among probucol/PVP/SDS multicomponent system investigated by solid-state NMR. | Pharmaceutical research 20061101 |
Role of probucol in inhibiting intimal hyperplasia after coronary stent implantation: a randomized study. | American heart journal 20061101 |
Application of 18F-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061101 |
Combined effect of probucol and insulin on renal damage in diabetic rats fed a high cholesterol diet. | European journal of pharmacology 20061024 |
[Can antioxidants prevent atherosclerosis?]. | Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 20061001 |
Antioxidants suppress plasma levels of lectinlike oxidized low-density lipoprotein receptor-ligands and reduce atherosclerosis in watanabe heritable hyperlipidemic rabbits. | Journal of cardiovascular pharmacology 20061001 |
Human urotensin-II potentiates the mitogenic effect of mildly oxidized low-density lipoprotein on vascular smooth muscle cells: comparison with other vasoactive agents and hydrogen peroxide. | Hypertension research : official journal of the Japanese Society of Hypertension 20061001 |
Dietary phytosterols reduce probucol-induced atherogenesis in apo E-KO mice. | Atherosclerosis 20060901 |
The in vitro effects of a novel vascular protectant, AGI-1067, on platelet aggregation and major receptor expression in subjects with multiple risk factors for vascular disease. | Journal of cardiovascular pharmacology and therapeutics 20060901 |
Tripterine inhibits the expression of adhesion molecules in activated endothelial cells. | Journal of leukocyte biology 20060801 |
Probucol decreases asymmetrical dimethylarginine level by alternation of protein arginine methyltransferase I and dimethylarginine dimethylaminohydrolase activity. | Cardiovascular drugs and therapy 20060801 |
Both hepatitis C virus and Chlamydia pneumoniae infection are related to the progression of carotid atherosclerosis in patients undergoing lipid lowering therapy. | Fukuoka igaku zasshi = Hukuoka acta medica 20060801 |
Protective effect of calceolarioside on adriamycin-induced cardiomyocyte toxicity. | European journal of pharmacology 20060710 |
Importance of acyl-coenzyme A:cholesterol acyltransferase 1/2 dual inhibition for anti-atherosclerotic potency of pactimibe. | European journal of pharmacology 20060701 |
[Beneficial effects of probucol on endothelial function in patients with acute coronary syndrome]. | Zhonghua xin xue guan bing za zhi 20060701 |
Induction of adiponectin in skeletal muscle of type 2 diabetic mice: In vivo and in vitro studies. | Diabetologia 20060601 |
CETP levels rather than polymorphisms as markers of coronary risk: healthy athlete with high HDL-C and coronary disease--effectiveness of probucol. | Atherosclerosis 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Are small biotechs still underselling themselves? | Nature biotechnology 20060501 |
[Effects of xuezhikang capsules on vascular endothelial function and redox status in patients with coronary heart disease]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060501 |
Phenolic compounds from the roots of Lindera fruticosa. | Journal of natural products 20060501 |
Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy. | Journal of cardiovascular pharmacology 20060501 |
[Effect of probucol and losartan on growth factors after balloon angioplasty in rabbits]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20060401 |
LDL-antioxidant pterocarpans from roots of Glycine max (L.) Merr. | Journal of agricultural and food chemistry 20060322 |
Relative contributions of ABCA1 and SR-BI to cholesterol efflux to serum from fibroblasts and macrophages. | Arteriosclerosis, thrombosis, and vascular biology 20060301 |
Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progressive mesangioproliferative glomerulonephritis in the rat. | Journal of the American Society of Nephrology : JASN 20060301 |
Determination of DPPH free radical scavenging activity by reversed-phase HPLC: a sensitive screening method for polyherbal formulations. | Journal of pharmaceutical and biomedical analysis 20060213 |
Probucol delays progression of diabetic nephropathy. | Diabetes research and clinical practice 20060201 |
Cyclic diarylheptanoids inhibit cell-mediated low-density lipoprotein oxidation. | Natural product research 20060201 |
Antioxidants: the good, the bad and the ugly. | The Canadian journal of cardiology 20060201 |
Probucol and atorvastatin decrease urinary 8-hydroxy-2'-deoxyguanosine in patients with diabetes and hypercholesterolemia. | Journal of atherosclerosis and thrombosis 20060201 |
Drug nanoparticle formation from drug/HPMC/SDS ternary ground mixtures. | Die Pharmazie 20060201 |
Review article: Drug therapy for non-alcoholic fatty liver disease. | Alimentary pharmacology & therapeutics 20060115 |
Macrophage apolipoprotein E reduces atherosclerosis and prevents premature death in apolipoprotein E and scavenger receptor-class BI double-knockout mice. | Arteriosclerosis, thrombosis, and vascular biology 20060101 |
Cyclic diarylheptanoids inhibit cell mediated low-density lipoprotein oxidation. | Natural product research 20060101 |
Chemical structure-dependent gene expression of proteasome subunits via regulation of the antioxidant response element. | Free radical research 20060101 |
AGI-1067: a novel vascular protectant for prevention of restenosis. | The Annals of pharmacotherapy 20060101 |
Probucol up-regulates paraoxonase 1 expression in hepatocytes of hypercholesterolemic rabbits. | Journal of cardiovascular pharmacology 20060101 |
Evaluation of the rabbit Purkinje fibre assay as an in vitro tool for assessing the risk of drug-induced torsades de pointes in humans. | Drug safety 20060101 |
Effect of probucol on elderly hypercholesterolemic patients in the FAST study. | Fukuoka igaku zasshi = Hukuoka acta medica 20060101 |
Different inflammatory response and oxidative stress in neointimal hyperplasia after balloon angioplasty and stent implantation in cholesterol-fed rabbits. | Pathology, research and practice 20060101 |
Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis. | Annual review of nutrition 20060101 |
Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens. | BMC neuroscience 20060101 |
[Interaction between dinitrosyl iron complexes and intermediate products of oxidative stress]. | Biofizika 20060101 |
Effects of alpha tocopherol and probucol supplements on allergen-induced airway inflammation and hyperresponsiveness in a mouse model of allergic asthma. | International archives of allergy and immunology 20060101 |
The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. | Lipids in health and disease 20060101 |
Bifidobacterium infantis strains with and without a combination of oligofructose and inulin (OFI) attenuate inflammation in DSS-induced colitis in rats. | BMC gastroenterology 20060101 |
Pretreatment with probucol attenuates cardiomyocyte apoptosis in a rabbit model of ischemia/reperfusion. | Scandinavian journal of clinical and laboratory investigation 20060101 |
[The role of epsilon 2/epsilon 3/epsilon 4 polymorphism of the apolipoprotein E gene in the development of dislipoproteinemia and its influence on the efficacy of the hypolipidemic therapy]. | TSitologiia i genetika 20060101 |
Dietary probucol preserves endothelium-dependent relaxation of arteriovenous fistula in hypercholesterolemic rabbits. | Chang Gung medical journal 20060101 |
Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials. | Chinese medicine 20060101 |
Inhibition of vascular remodelling in a porcine coronary injury model by herbal extract XS0601. | Chinese medicine 20060101 |
[Effect of Panavir on influenza A virus reproduction]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101 |
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans. | The Journal of biological chemistry 20051230 |
Design, synthesis, and evaluation of pharmacological properties of cinnamic derivatives as antiatherogenic agents. | Journal of medicinal chemistry 20051229 |
[Oxidative stress and cardiovascular diseases]. | Deutsche medizinische Wochenschrift (1946) 20051216 |
Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20051201 |
Influence of amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats. | Journal of nutritional science and vitaminology 20051201 |
Reduction of oxidative stress and apoptosis in hyperlipidemic rabbits by ellagic acid. | The Journal of nutritional biochemistry 20051101 |
Probucol enhances the expression of human hepatic scavenger receptor class B type I, possibly through a species-specific mechanism. | Arteriosclerosis, thrombosis, and vascular biology 20051101 |
In vitro and in vivo effects of probucol on hydrolysis of asymmetric dimethyl L-arginine and vasospasm in primates. | Journal of neurosurgery 20051001 |
Ten-year follow-up of familial hypercholesterolemia patients after intensive cholesterol-lowering therapy. | International heart journal 20050901 |
A case of familial hypercholesterolemia; secession from LDL-apheresis by the drug treatment with potent statin and resin. | The Tokai journal of experimental and clinical medicine 20050901 |
Processes involved in the site-specific effect of probucol on atherosclerosis in apolipoprotein E gene knockout mice. | Arteriosclerosis, thrombosis, and vascular biology 20050801 |
Enzymatic characterization of lipid-based drug delivery systems. | International journal of pharmaceutics 20050725 |
Cholesterol levels and statin use in patients with coronary heart disease treated in primary care settings. | Preventing chronic disease 20050701 |
[Long QT syndrome]. | Nihon rinsho. Japanese journal of clinical medicine 20050701 |
Study of antiparkinsonic activity of panavir on a model of Parkinson syndrome induced by systemic administration of MPTP to outbred rats and C57Bl/6 mice. | Bulletin of experimental biology and medicine 20050701 |
Are we over oxidized? Oxidative stress, cardiovascular disease, and the future of intervention studies with antioxidants. | Vascular health and risk management 20050601 |
AGIX-4207 [2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid], a novel antioxidant and anti-inflammatory compound: cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression. | The Journal of pharmacology and experimental therapeutics 20050501 |
Effort angina in a middle-aged woman with abnormally high levels of serum high-density lipoprotein cholesterol: a case of cholesteryl-ester transfer protein deficiency. | Circulation journal : official journal of the Japanese Circulation Society 20050501 |
Reduction of oxidative stress and atherosclerosis in hyperlipidemic rabbits by Dioscorea rhizome. | Canadian journal of physiology and pharmacology 20050501 |
Probucol protects against hypochlorite-induced endothelial dysfunction: identification of a novel pathway of probucol oxidation to a biologically active intermediate. | The Journal of biological chemistry 20050422 |
Combined effect of probucol and insulin on cataracts of diabetic rats fed a high cholesterol diet. | European journal of pharmacology 20050418 |
Probucol attenuates oxidative stress and energy decline in isoproterenol-induced heart failure in rat. | Pharmacological research 20050401 |
Anthocyanins increase low-density lipoprotein and plasma cholesterol and do not reduce atherosclerosis in Watanabe Heritable Hyperlipidemic rabbits. | Molecular nutrition & food research 20050401 |
Involvement of mitogen-activated protein kinases in adriamycin-induced cardiomyopathy. | American journal of physiology. Heart and circulatory physiology 20050401 |
Suppressive effects of cacao liquor polyphenols (CLP) on LDL oxidation and the development of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbits. | Atherosclerosis 20050401 |
Na+/H+ exchange inhibition and antioxidants lack additive protective effects after reperfusion injury in the working heterotopic rat heart isograft. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401 |
Apolipoprotein E, cholesterol transport and synthesis in sporadic Alzheimer's disease. | Neurobiology of aging 20050301 |
Antioxidants and atherosclerosis: emerging drug therapies. | Current atherosclerosis reports 20050201 |
Low daily dose of antioxidant probucol decreases incidence and severity of restenosis after transluminal coronary balloon angioplasty. | Bulletin of experimental biology and medicine 20050201 |
On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway. | Journal of lipid research 20050101 |
Effect of anti-oxidant (carvedilol and probucol) loaded stents in a porcine coronary restenosis model. | Circulation journal : official journal of the Japanese Circulation Society 20050101 |
Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release. | BMC neuroscience 20050101 |
Protection of cortical cells by equine estrogens against glutamate-induced excitotoxicity is mediated through a calcium independent mechanism. | BMC neuroscience 20050101 |
Danshen inhibits oxysterol-induced endothelial cell apoptosis in vivo. | Journal of atherosclerosis and thrombosis 20050101 |
Oxidative stress and pancreatic beta-cell dysfunction. | American journal of therapeutics 20050101 |
Vitamin E supplementation alters HDL-cholesterol concentration and paraoxonase activity in rabbits fed high-cholesterol diet: comparison with probucol. | Journal of biochemical and molecular toxicology 20050101 |
Inhibition of lipoprotein lipid oxidation. | Handbook of experimental pharmacology 20050101 |
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases. | Journal of medicinal chemistry 20041202 |
Probucol inhibits ABCA1-mediated cellular lipid efflux. | Arteriosclerosis, thrombosis, and vascular biology 20041201 |
Effects of probucol versus aspirin and versus brachytherapy on restenosis after femoropopliteal angioplasty: the PAB randomized multicenter trial. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20041201 |
Antioxidant activities of a new lignan and a neolignan from Saururus chinensis. | Bioorganic & medicinal chemistry letters 20041115 |
Carvedilol inhibits tumor necrosis factor-alpha-induced endothelial transcription factor activation, adhesion molecule expression, and adhesiveness to human mononuclear cells. | Arteriosclerosis, thrombosis, and vascular biology 20041101 |
Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20041101 |
HMG CoA reductase inhibitors (statins) for dialysis patients. | The Cochrane database of systematic reviews 20041018 |
3,4,5,6-Tetrahydroxyxanthone prevents vascular endothelial cell apoptosis induced by high glucose. | Naunyn-Schmiedeberg's archives of pharmacology 20041001 |
Mixed connective tissue disease associated with antineutrophil cytoplasmic antibodies against proteinase-3 and systemic atherosclerosis: a case report. | Clinical rheumatology 20041001 |
Combined effects of an anticoagulant and a lipid-lowering agent on the prevention of steroid-induced osteonecrosis in rabbits. | Arthritis and rheumatism 20041001 |
Concurrent therapies that protect against doxorubicin-induced cardiomyopathy. | Clinical journal of oncology nursing 20041001 |
Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1. | Circulation 20040928 |
Synthesis of cinnamic acid derivatives and their inhibitory effects on LDL-oxidation, acyl-CoA:cholesterol acyltransferase-1 and -2 activity, and decrease of HDL-particle size. | Bioorganic & medicinal chemistry letters 20040920 |
[NO and atherosclerosis]. | Nihon rinsho. Japanese journal of clinical medicine 20040901 |
[Study of diagnostic criteria of intima-media thickening and effects of drugs on peripheral arteries]. | Zhonghua yi xue za zhi 20040802 |
Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG. | Clinical science (London, England : 1979) 20040801 |
Inhibitory effects of multi-substituted benzylidenethiazolidine-2,4-diones on LDL oxidation. | Bioorganic & medicinal chemistry 20040801 |
Antioxidant role of human haptoglobin. | Proteomics 20040801 |
Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases. | Acta pharmacologica Sinica 20040801 |
Probucol inactivates ABCA1 in the plasma membrane with respect to its mediation of apolipoprotein binding and high density lipoprotein assembly and to its proteolytic degradation. | The Journal of biological chemistry 20040716 |
Oligodendrocytes are susceptible to apoptotic cell death induced by prion protein-derived peptides. | Glia 20040701 |
Novel 3,5-diaryl pyrazolines and pyrazole as low-density lipoprotein (LDL) oxidation inhibitor. | Bioorganic & medicinal chemistry letters 20040607 |
Probucol and ticlopidine: effect on platelet and monocyte activation markers in hyperlipidemic patients with and without type 2 diabetes. | Atherosclerosis 20040601 |
Pravastatin has an additional depressor effect in patients undergoing long-term treatment with antihypertensive drugs. | American journal of hypertension 20040601 |
Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells. | European journal of biochemistry 20040601 |
Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice. | Pharmaceutical research 20040601 |
Acteoside protects endothelial cells against free radical-induced oxidative stress. | The Journal of pharmacy and pharmacology 20040601 |
New drugs to improve transplant outcomes. | Transplantation 20040515 |
Carvedilol inhibits basal and stimulated ACE production in human endothelial cells. | Journal of cardiovascular pharmacology 20040501 |
Effect of probucol on the oral bioavailability of cyclosporine A. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040501 |
Long-term treatment with probucol improves endothelial function in patients with coronary artery disease. | Hypertension research : official journal of the Japanese Society of Hypertension 20040501 |
Liquid chromatographic method for the simultaneous determination of different lipid-soluble antioxidants in human plasma and low-density lipoproteins. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040425 |
Regulation of mitochondrial transcription factor A expression by high glucose. | Annals of the New York Academy of Sciences 20040401 |
[Effect of xiongshao capsule on vascular remodeling in rabbit with experimental atherosclerosis]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040401 |
Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein. | The Journal of biological chemistry 20040312 |
Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: a novel antioxidant and anti-inflammatory agent. | The Journal of pharmacology and experimental therapeutics 20040301 |
Redox processes underlying the vascular repair reaction. | World journal of surgery 20040301 |
Effect of probucol on neointimal thickening in a stent porcine restenosis model. | Japanese heart journal 20040301 |
Protective mechanisms against peptide and protein peroxides generated by singlet oxygen. | Free radical biology & medicine 20040215 |
Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway. | The Journal of biological chemistry 20040206 |
Potent antioxidant properties of 4-hydroxyl-propranolol. | The Journal of pharmacology and experimental therapeutics 20040101 |
Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc. | Journal of pharmacological and toxicological methods 20040101 |
Cardioprotective effects of carvedilol on acute autoimmune myocarditis: anti-inflammatory effects associated with antioxidant property. | American journal of physiology. Heart and circulatory physiology 20040101 |
Alpha-tocopherol preserves endothelial cell migration in the presence of cell-oxidized low-density lipoprotein by inhibiting changes in cell membrane fluidity. | Journal of vascular surgery 20040101 |
Effects of probucol on renal function and urinary protein excretion in spontaneously hypercholesterolemic rats fed a normal or high cholesterol diet. | Kidney & blood pressure research 20040101 |
Plant sterols: factors affecting their efficacy and safety as functional food ingredients. | Lipids in health and disease 20040101 |
Role of antioxidant enzymes and antioxidant compound probucol in antiradical protection of pancreatic beta-cells during alloxan-induced diabetes. | Bulletin of experimental biology and medicine 20040101 |
Effect of Lovastatin on lipid peroxidation and total antioxidant concentrations in hemodialysis patients. | Lipids in health and disease 20040101 |
Amelioration of the beta-cell dysfunction in diabetic APA hamsters by antioxidants and AGE inhibitor treatments. | Diabetes/metabolism research and reviews 20040101 |
Management of hyperlipidaemia associated with heart transplantation. | Drugs 20040101 |
Exploring effects of different antioxidants on dexamethasone-induced lipid peroxidation using common laboratory markers. | Acta poloniae pharmaceutica 20040101 |
Ciprofibrate therapy in patients with hypertriglyceridemia and low high density lipoprotein (HDL)-cholesterol: greater reduction of non-HDL cholesterol in subjects with excess body weight (The CIPROAMLAT study). | Cardiovascular diabetology 20040101 |
Probucol as a potent inhibitor of oxygen radical-induced lipid peroxidation and DNA damage: in vitro studies. | Redox report : communications in free radical research 20040101 |
Probucol, a hypocholesterolemic agent, prevents the development of uterine adenomyosis induced by pituitary grafting in mice. | Anticancer research 20040101 |
Oxidized low-density lipoprotein and 15-deoxy-delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells. | American journal of physiology. Heart and circulatory physiology 20031201 |
Pharmacologic prevention of both restenosis and atherosclerosis progression: AGI-1067, probucol, statins, folic acid and other therapies. | Current opinion in lipidology 20031201 |
Cytotoxic cellular cholesterol is selectively removed by apoA-I via ABCA1. | Atherosclerosis 20031201 |
Association of Chlamydia pneumoniae antibody with the cholesterol-lowering effect of statins. | Atherosclerosis 20031201 |
Homozygous familial hypercholesterolaemia: development of xanthogranuloma in a boy at puberty under long-term low-density lipoprotein apheresis and drug therapy. | The British journal of dermatology 20031201 |
Induction of NAD(P)H:quinone reductase by probucol: a possible mechanism for protection against chemical carcinogenesis and toxicity. | Pharmacology & toxicology 20031201 |
Direct vascular effects of HR780, a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. | Clinical and experimental pharmacology & physiology 20031201 |
Dietary prevention of post-angioplasty restenosis. From illusion and disillusion to pragmatism. | Nutrition, metabolism, and cardiovascular diseases : NMCD 20031201 |
New aspects in probucol cardioprotection against doxorubicin-induced cardiotoxicity. | Cancer chemotherapy and pharmacology 20031101 |
Experimental and clinical studies show that the probucol derivative AGI-1067 prevents vascular growth. | Expert opinion on investigational drugs 20031101 |
Modulation of HDL metabolism by probucol in complete cholesteryl ester transfer protein deficiency. | Atherosclerosis 20031101 |
Probucol restores the defective leukocyte-endothelial interaction in experimental diabetes. | European journal of pharmacology 20031008 |
Probucol decreases mevalonate pyrophosphate decarboxylase in the rat liver. | Biological & pharmaceutical bulletin 20031001 |
Cytochrome P450-mediated oxidative damage of nuclear membrane proteins and its prevention by vitamin C. | Indian journal of biochemistry & biophysics 20031001 |
Ginkgo biloba extract inhibits tumor necrosis factor-alpha-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells. | Arteriosclerosis, thrombosis, and vascular biology 20030901 |
Foreign body-type multinucleated giant cell formation is potently induced by alpha-tocopherol and prevented by the diacylglycerol kinase inhibitor R59022. | The American journal of pathology 20030901 |
Optimizing probucol administration to preserve left ventricular compliance after reperfusion injury in the heterotopic rat heart isograft. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030901 |
Vascular protectants for the treatment of atherosclerosis. | Expert review of cardiovascular therapy 20030901 |
Novel 3-O-acyl mesquitol analogues as free-radical scavengers and enzyme inhibitors: synthesis, biological evaluation and structure-activity relationship. | Bioorganic & medicinal chemistry letters 20030818 |
Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats. | Journal of the American Society of Nephrology : JASN 20030801 |
Effect of antioxidant probucol on cell-mediated LDL oxidation in vitro and in vivo. | Bulletin of experimental biology and medicine 20030801 |
Interrelation between compensation of carbohydrate metabolism and severity of manifestations of oxidative stress in type II diabetes mellitus. | Bulletin of experimental biology and medicine 20030801 |
Design and synthesis of 4,6-di-tert-butyl-2,3-dihydro-5-benzofuranols as a novel series of antiatherogenic antioxidants. | Journal of medicinal chemistry 20030703 |
NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy. | Journal of molecular and cellular cardiology 20030701 |
Mechanisms of glomerular immune injury: effects of antioxidant treatment. | Journal of the American Society of Nephrology : JASN 20030701 |
Signal jammer. An academic experiment leads to a new class of drug for attacking heart disease. | Scientific American 20030701 |
Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins. | Molecular and cellular biochemistry 20030701 |
Protective effects of probucol treatment on pancreatic beta-cell function of SZ-induced diabetic APA hamsters. | Experimental animals 20030701 |
AGI-1067: a multifunctional phenolic antioxidant, lipid modulator, anti-inflammatory and antiatherosclerotic agent. | The Journal of pharmacology and experimental therapeutics 20030601 |
Oxidized low-density lipoprotein inhibits endothelium-dependent vasodilation by an antioxidant-sensitive, lysophosphatidylcholine-independent mechanism. | Journal of cardiovascular pharmacology 20030601 |
Effects of candesartan and probucol on restenosis after coronary stenting: results of insight of stent intimal hyperplasia inhibition by new angiotensin II receptor antagonist (ISHIN) trial. | Circulation journal : official journal of the Japanese Circulation Society 20030601 |
A water-extract of the Korean traditional formulation Geiji-Bokryung-Hwan reduces atherosclerosis and hypercholesteremia in cholesterol-fed rabbits. | International immunopharmacology 20030501 |
Probucol promotes functional reendothelialization in balloon-injured rabbit aortas. | Circulation 20030422 |
Antioxidants, statins, and atherosclerosis. | Journal of the American College of Cardiology 20030402 |
Probucol in the treatment of non-alcoholic steatohepatitis: a double-blind randomized controlled study. | Journal of hepatology 20030401 |
[Prevention of restenosis after PTCA and patient's QOL]. | Nihon rinsho. Japanese journal of clinical medicine 20030401 |
[Prevention of postangioplasty restenosis]. | Nihon rinsho. Japanese journal of clinical medicine 20030401 |
[Treatment of high blood cholesterol in patients with coronary heart disease]. | Nihon rinsho. Japanese journal of clinical medicine 20030401 |
Tumor necrosis factor-alpha in low doses preactivates and activates macrophages by increasing their ability to produce reactive oxygen species and oxidize low-density lipoproteins: protective effect of antioxidants. | Bulletin of experimental biology and medicine 20030401 |
NF-kappa B activation in endothelial cells treated with oxidized high-density lipoprotein. | Biochemical and biophysical research communications 20030328 |
Amlodipine inhibits doxorubicin-induced apoptosis in neonatal rat cardiac myocytes. | Journal of the American College of Cardiology 20030305 |
Optimal management of nonalcoholic fatty liver/steatohepatitis. | Journal of clinical gastroenterology 20030301 |
Probucol in the treatment of nonalcoholic steatohepatitis: an open-labeled study. | Journal of clinical gastroenterology 20030301 |
Differential effects of catalase on apoptosis induction in human promonocytic cells. Relationships with heat-shock protein expression. | Molecular pharmacology 20030301 |
Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. | Trends in molecular medicine 20030301 |
Chemistry and pharmacology of vascular protectants: a novel approach to the treatment of atherosclerosis and coronary artery disease. | The American journal of cardiology 20030206 |
Clinical results with AGI-1067: a novel antioxidant vascular protectant. | The American journal of cardiology 20030206 |
Effects of AGI-1067 and probucol after percutaneous coronary interventions. | Circulation 20030204 |
Apoptotic neuronal cell death induced by the non-fibrillar amyloid-beta peptide proceeds through an early reactive oxygen species-dependent cytoskeleton perturbation. | The Journal of biological chemistry 20030131 |
Hypercholesterolemia is a prerequisite for puromycin inducible damage in mouse kidney. | Kidney international 20030101 |
Resolution of typical lipoprotein glomerulopathy by intensive lipid-lowering therapy. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20030101 |
Oxidized low-density lipoprotein and high-density lipoprotein cholesterol modulate coronary arterial remodeling: an intravascular ultrasound study. | Clinical cardiology 20030101 |
Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients. | Drugs 20030101 |
Ascorbic acid augments cytotoxicity induced by oxidized low-density lipoprotein. | Journal of atherosclerosis and thrombosis 20030101 |
Alpha-tocopherol modulates the low density lipoprotein receptor of human HepG2 cells. | Nutrition journal 20030101 |
The antiatherogenic effect of DiNAC: experimental findings supporting immunomodulation as a new treatment for atherosclerosis related diseases. | Cardiovascular drug reviews 20030101 |
Potential role of the interaction between equine estrogens, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in the prevention of coronary heart and neurodegenerative diseases in postmenopausal women. | Lipids in health and disease 20030101 |
Effects of probucol on endothelial damage by 5-fluorouracil. | Acta oncologica (Stockholm, Sweden) 20030101 |
The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease. | Neuroscience 20030101 |
Protection against acute adriamycin-induced cardiotoxicity by garlic: role of endogenous antioxidants and inhibition of TNF-alpha expression. | BMC pharmacology 20030101 |
Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death. | BMC neuroscience 20030101 |
[The history of experimental diabetes in Iaşi ]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101 |
[The use of antioxidants and antihypoxants for decreasing of LDL oxidation by macrophages and endothelial cells in ischemia and reperfusion of vascular wall]. | Biomeditsinskaia khimiia 20030101 |
Effect of antioxidant probucol for preventing stent restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20021201 |
[Effect of probucol on the blood concentration of cyclosporin A in patients with nephrotic syndrome: a case study with a microemulsion formulation (Neoral)]. | Nihon Jinzo Gakkai shi 20021201 |
Nitric oxide releasing morpholine derivatives as hypolipidemic and antioxidant agents. | Journal of medicinal chemistry 20021121 |
Application of quantitative competitive polymerase chain reaction for measurements of mRNA from antioxidative enzymes in the diabetic rat retina and kidney. | Metabolism: clinical and experimental 20021001 |
Antioxidative effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001 |
The effect of probucol on atherosclerosis in streptozotocin-induced diabetic-hyperlipidemic APA hamsters in different stages of atherosclerosis. | Experimental animals 20021001 |
Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification. | Endocrinology 20020901 |
Mitogenic activity of oxidized lipoprotein (a) on human vascular smooth muscle cells. | Hypertension (Dallas, Tex. : 1979) 20020901 |
Japanese familial hypercholesterolaemia with a 327insC mutation in the LDL receptor gene. | Annals of clinical biochemistry 20020901 |
Evaluation of pharmacokinetic interaction between cyclosporin A and probucol in rats. | Pharmaceutical research 20020901 |
Gateways to Clinical Trials. | Methods and findings in experimental and clinical pharmacology 20020901 |
Comparison of the effects of alpha-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits. | Atherosclerosis 20020801 |
Effect of probucol on cytochrome P450 activities in human liver microsomes. | Biological & pharmaceutical bulletin 20020801 |
Effects of probucol in hyperlipidemic rabbit liver: a preliminary ultrastructural study. | Okajimas folia anatomica Japonica 20020801 |
Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation. | Circulation 20020716 |
Probucol preserves pancreatic beta-cell function through reduction of oxidative stress in type 2 diabetes. | Diabetes research and clinical practice 20020701 |
DNA damage and the effect of antioxidants in streptozotocin-treated mice. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020701 |
Potential emerging therapeutic strategies to prevent restenosis in the peripheral vasculature. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020701 |
Intensification of free radical oxidation of low-density lipoproteins in the plasma of patients with ischemic heart disease receiving beta-hydroxy-beta-methylglutaryl-coenzyme A reductase inhibitor cerivastatin and inhibition of low-density lipoprotein peroxidation with antioxidant probucol. | Bulletin of experimental biology and medicine 20020701 |
Antioxidative activity of green tea polyphenol in cholesterol-fed rats. | Journal of agricultural and food chemistry 20020605 |
Probucol inhibits oxidized-low density lipoprotein-induced adhesion of monocytes to endothelial cells in vitro. | Acta pharmacologica Sinica 20020601 |
Antioxidative and hypolipidemic effects of barley leaf essence in a rabbit model of atherosclerosis. | Japanese journal of pharmacology 20020601 |
Policosanol: a new treatment for cardiovascular disease? | Alternative medicine review : a journal of clinical therapeutic 20020601 |
Beneficial effects of long-term use of the antioxidant probucol in heart failure in the rat. | Circulation 20020528 |
Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis. | Circulation 20020514 |
Inhibitory effect of a novel water-soluble vitamin E derivative on atherosclerosis in rabbits. | Atherosclerosis 20020501 |
Stilbazulenyl nitrone (STAZN): a nitronyl-substituted hydrocarbon with the potency of classical phenolic chain-breaking antioxidants. | Journal of the American Chemical Society 20020501 |
Immunomodulation with DiNAC-- a new approach to the treatment of atherosclerosis? | Expert opinion on investigational drugs 20020501 |
2,3,4-Trimethyl-5,7-dihydroxy-2,3-dihydrobenzofuran, a novel antioxidant, from Penicillium citrinum F5. | Journal of natural products 20020501 |
Anti-lipid-peroxidative principles from Tournefortia sarmentosa. | Journal of natural products 20020501 |
[Anti-hyperlipidemic agents]. | Nihon rinsho. Japanese journal of clinical medicine 20020501 |
Effects of antioxidants on kidney disease. | Mechanisms of ageing and development 20020430 |
The effect of antioxidants on glycated albumin-induced cytotoxicity in bovine retinal pericytes. | Biochemical and biophysical research communications 20020412 |
Effect of BO-653 and probucol on c-MYC and PDGF-A messenger RNA of the iliac artery after balloon denudation in cholesterol-fed rabbits. | Atherosclerosis 20020401 |
Comparison of antioxidant effects of naringin and probucol in cholesterol-fed rabbits. | Clinica chimica acta; international journal of clinical chemistry 20020301 |
Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level. | British journal of pharmacology 20020301 |
Effects of plaque composition on vascular remodelling after angioplasty in the MultiVitamins and Probucol (MVP) trial. | The Canadian journal of cardiology 20020301 |
[Pharmacokinetics and relative bioavailability of probucol inclusion complex capsule in healthy dogs]. | Yao xue xue bao = Acta pharmaceutica Sinica 20020301 |
Antioxidant treatment of therapy-resistant idiopathic membranous nephropathy with probucol: a pilot study. | Wiener klinische Wochenschrift 20020227 |
Effects of probucol and pravastatin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia. Fukuoka Atherosclerosis Trial (FAST). | Journal of the American College of Cardiology 20020220 |
Improved post-myocardial infarction survival with probucol in rats: effects on left ventricular function, morphology, cardiac oxidative stress and cytokine expression. | Journal of the American College of Cardiology 20020102 |
Macrophages take up triacylglycerol-rich emulsions at a faster rate upon co-incubation with native and modified LDL: An investigation on the role of natural chylomicrons in atherosclerosis. | Journal of cellular biochemistry 20020101 |
Drug reverses coronary atherosclerosis. | Drug discovery today 20020101 |
Esophageal cancer and the esophagus: challenges and potential strategies for selective cytoprotection of the tumor-bearing organ during cancer treatment. | Seminars in radiation oncology 20020101 |
Effects of Ginkgo biloba extract on the proliferation of vascular smooth muscle cells in vitro and on intimal thickening and interleukin-1beta expression after balloon injury in cholesterol-fed rabbits in vivo. | Journal of cellular biochemistry 20020101 |
Effects of pravastatin on exercise electrocardiography test performance and cardiovascular mortality and morbidity in patients with hypercholesterolemia: Lipid Intervention Study in Kyoto. | Circulation journal : official journal of the Japanese Circulation Society 20020101 |
Probucol and liver efficiency during chemically-induced hepatocarcinogenesis. | Anticancer research 20020101 |
Evaluation of probucol as suppressor of ceftizoxime induced lipid peroxidation. | Acta poloniae pharmaceutica 20020101 |
The protective effects of tetrahydrocurcumin on oxidative stress in cholesterol-fed rabbits. | Journal of atherosclerosis and thrombosis 20020101 |
Effects of inhibition of glycation and oxidative stress on the development of diabetic nephropathy in rats. | Journal of diabetes and its complications 20020101 |
[Invasive cardiology: focus on restenosis. Part II]. | Kardiologiia 20020101 |
Prevention of restenosis with antioxidants: mechanisms and implications. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101 |
Relationship between free radicals produced by entamoeba histolytica and its proteases complex activity. | Revista latinoamericana de microbiologia 20020101 |
Effects of insulin and antioxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxyguanosine in streptozotocin-induced diabetic rats. | Diabetes 20011201 |
Abnormal lipoprotein metabolism and reversible female infertility in HDL receptor (SR-BI)-deficient mice. | The Journal of clinical investigation 20011201 |
Low-density lipoprotein-antioxidant constituents of Saururus chinensis. | Journal of natural products 20011201 |
[Lipid-lowering drugs]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20011201 |
Antioxidative effects of fluvastatin and its metabolites against oxidative DNA damage in mammalian cultured cells. | Free radical research 20011201 |
Fluvastatin depresses the enhanced lipid peroxidation in vitamin E-deficient hamsters. | Free radical research 20011201 |
Cyclodextrins in the treatment of a mouse model of Niemann-Pick C disease. | Life sciences 20011130 |
A novel series of 2,6,7-substituted 2,3-dihydro-1,4-benzodioxin and 2,6,7-substituted 1,4-benzodioxin derivatives as lipid peroxidation inhibitors. Structure-activity relationships for high inhibition of human low-density lipoprotein peroxidation. | Journal of medicinal chemistry 20011108 |
Anti-atherogenic antioxidants regulate the expression and function of proteasome alpha-type subunits in human endothelial cells. | The Journal of biological chemistry 20011102 |
Dietary hematein ameliorates fatty streak lesions in the rabbit by the possible mechanism of reducing VCAM-1 and MCP-1 expression. | Atherosclerosis 20011101 |
Allergic reactions at repeat femoral angiography with ioxaglate. | Acta radiologica (Stockholm, Sweden : 1987) 20011101 |
N,N'-diacetyl-L-cystine (DiNAC), the disulphide dimer of N-acetylcysteine, inhibits atherosclerosis in WHHL rabbits: evidence for immunomodulatory agents as a new approach to prevent atherosclerosis. | The Journal of pharmacology and experimental therapeutics 20011001 |
A dynamic in vitro lipolysis model. II: Evaluation of the model. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20011001 |
Antioxidant compounds and Ca(2+) pathway blockers differentially protect against methylmercury and mercuric chloride neurotoxicity. | Journal of neuroscience research 20011001 |
[Effect of probucol on the concentration of cyclosporin A in patients with nephrotic syndrome]. | Nihon Jinzo Gakkai shi 20011001 |
Retinal glial cell immunoreactivity and neuronal cell changes in rats with STZ-induced diabetes. | Current eye research 20011001 |
Alpha-tocopherol and probucol reduce autoantibody titer to MDA-LDL in hypercholesterolemic rabbits. | Free radical biology & medicine 20010915 |
Endothelin-1 synthesis and endothelin B receptor expression in human coronary artery smooth muscle cells and monocyte-derived macrophages is up-regulated by low density lipoproteins. | Journal of molecular and cellular cardiology 20010901 |
Restenosis drug discovery--a formidable task. | Current opinion in investigational drugs (London, England : 2000) 20010901 |
Inhibitory effects of fluvastain and its metabolites on the formation of several reactive oxygen species. | Life sciences 20010810 |
Action of the novel antioxidants 4GBE43 and 2BBE43 against lipid peroxidation. | Biochemical pharmacology 20010801 |
Oxidants and antioxidants in atherosclerosis. | Current opinion in lipidology 20010801 |
Antioxidative properties of probucol estimated by the reactivity with superoxide and by electrochemical oxidation. | Chemical & pharmaceutical bulletin 20010801 |
Angiotensin-converting enzyme inhibitors and probucol suppress the time-dependent increase in urinary Type IV collagen excretion of Type II diabetes mellitus patients with early diabetic nephropathy. | Clinical nephrology 20010801 |
Vascular dysfunction induced by AGE is mediated by VEGF via mechanisms involving reactive oxygen species, guanylate cyclase, and protein kinase C. | Microcirculation (New York, N.Y. : 1994) 20010801 |
Effects of probucol on atherosclerosis of apoE-deficient or LDL receptor-deficient mice. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010801 |
Apheresis technology for prevention and regression of atherosclerosis. | Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis 20010801 |
A comparison of alternative polymer excipients and processing methods for making solid dispersions of a poorly water soluble drug. | International journal of pharmaceutics 20010703 |
Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: antiapoptotic effect of antioxidant agents on endothelial cells. | Hypertension (Dallas, Tex. : 1979) 20010701 |
Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: effects of apolipoprotein E deficiency and probucol or phytosterol treatment. | Metabolism: clinical and experimental 20010601 |
Mildly oxidized low-density lipoprotein acts synergistically with angiotensin II in inducing vascular smooth muscle cell proliferation. | Journal of hypertension 20010601 |
Characterization of simple and reproducible vascular stenosis model in hypercholesterolemic hamsters. | Lipids 20010501 |
Inhibition of purified pig and human liver retinyl ester hydrolase by pharmacologic agents. | Lipids 20010501 |
The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide. | The Journal of biological chemistry 20010427 |
Structure, function and regulation of the ABC1 gene product. | Current opinion in lipidology 20010401 |
Treatment of hyperlipidemia in HIV-infected patients. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010401 |
Specific antioxidant activity of caffeoyl derivatives and other natural phenolic compounds: LDL protection against oxidation and decrease in the proinflammatory lysophosphatidylcholine production. | Journal of natural products 20010401 |
Selective inhibition by probucol of vascular cell adhesion molecule-1 (VCAM-1) expression in human vascular endothelial cells. | Atherosclerosis 20010301 |
Effect of probucol in lecithin-cholesterol acyltransferase-deficient mice: inhibition of 2 independent cellular cholesterol-releasing pathways in vivo. | Arteriosclerosis, thrombosis, and vascular biology 20010301 |
Protection against nitrofurantoin-induced oxidative stress by coelenterazine analogues and their oxidation products in rat hepatocytes. | Free radical research 20010301 |
Lipids and atherosclerosis: clinical management of hypercholesterolaemia. | Expert opinion on pharmacotherapy 20010301 |
[Pathogenesis of hypolipidemia]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
[Probucol]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
[Nicotinic acid and the derivative]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
[Antioxidants]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
[Treatments for dyslipidemia associated with kidney disease]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons. | The Journal of biological chemistry 20010216 |
Oxygen radicals mediate the final exacerbation of endothelin-1-induced gastric ulcer in rat. | European journal of pharmacology 20010209 |
The effect of pharmacological doses of different antioxidants on oxidation parameters and atherogenesis in hyperlipidaemic rabbits. | Atherosclerosis 20010201 |
Effects of probucol on rat carotid artery responses to balloon catheter injury. | Atherosclerosis 20010201 |
Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes. | The Journal of pharmacy and pharmacology 20010201 |
Apoptosis in adriamycin cardiomyopathy and its modulation by probucol. | Antioxidants & redox signaling 20010201 |
[Hyperlipidemia and cerebrovascular disease]. | Nihon rinsho. Japanese journal of clinical medicine 20010201 |
Antioxidant therapy attenuates JNK activation and apoptosis in the remote noninfarcted myocardium after large myocardial infarction. | Biochemical and biophysical research communications 20010112 |
Impact of residual plaque burden after balloon angioplasty in the MultiVitamins and Probucol (MVP) trial. | The Canadian journal of cardiology 20010101 |
A salvianolic acid B-rich fraction of Salvia miltiorrhiza induces neointimal cell apoptosis in rabbit angioplasty model. | Histology and histopathology 20010101 |
[Antioxidative effects of fluvastatin, and its major metabolites [II]]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010101 |
Polymorphisms in the Mn-SOD and EC-SOD genes and their relationship to diabetic neuropathy in type 1 diabetes mellitus. | BMC medical genetics 20010101 |
Effect of nilvadipine in weak acidic medium by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. | Arzneimittel-Forschung 20010101 |
Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-alpha-treated human aortic endothelial cells. | Journal of cellular biochemistry 20010101 |
Probucol decreases total body fat loss in VX2-carcinoma-induced cachectic rabbits. | Oncology reports 20010101 |
Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women. | Menopause (New York, N.Y.) 20010101 |
[Antioxidant effect of novel probucol analogs and their combinations with alpha-tocopherol]. | Voprosy meditsinskoi khimii 20010101 |
Evaluation of alpha-tocopherol, probucol and ascorbic acid as suppressors of digoxin induced lipid peroxidation. | Acta poloniae pharmaceutica 20010101 |
Oxidative stress and functional deficit in diabetic cardiomyopathy. | Advances in experimental medicine and biology 20010101 |
Type 2 diabetes: pharmacological intervention in an animal model. | Advances in experimental medicine and biology 20010101 |
[A 50-year history of new drugs in Japan: the developments and trends of antihyperlipidemic drugs]. | Yakushigaku zasshi 20010101 |
Structure-activity relationship of antioxidants for inhibitors of linoleic acid hydroperoxide-induced toxicity in cultured human umbilical vein endothelial cells. | Cytotechnology 20010101 |
Effects of probucol on cholesterol metabolism in mouse peritoneal macrophages: inhibition of HDL-mediated cholesterol efflux. | Atherosclerosis 20001001 |
Nephrin in experimental glomerular disease. | Kidney international 20001001 |
Effect of probucol on repeat revascularization rate after percutaneous transluminal coronary angioplasty (from the Probucol Angioplasty Restenosis Trial [PART]). | The American journal of cardiology 20000901 |
Effects of probucol on changes of antioxidant enzymes in adriamycin-induced cardiomyopathy in rats. | Cardiovascular research 20000601 |
Adriamycin-induced heart failure: mechanism and modulation. | Molecular and cellular biochemistry 20000401 |
Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity. | Kidney international 19991201 |
Attenuation of reperfusion injury with probucol in the heterotopic rat cardiac isograft. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 19990801 |
Combined effects of probucol and benzafibrate on lipoprotein metabolism and liver cholesteryl ester transfer protein mRNA in cholesterol-fed rabbits. | Japanese circulation journal 19990601 |
Zinc accumulation in adriamycin-induced cardiomyopathy in rats: effects of melatonin, a cardioprotective antioxidant. | Journal of pineal research 19990501 |
Effect of probucol on serum lipids, atherosclerosis and toxicology in fat-fed LDL receptor deficient mice. | Atherosclerosis 19981201 |
Some natural and synthetic antioxidants as stabilizers of beta-carotene conversion into vitamin A. | Biochemistry. Biokhimiia 19980201 |
Failure of antioxidant therapy to attenuate interstitial disease in rats with reversible nephrotic syndrome. | Journal of the American Society of Nephrology : JASN 19980201 |
Melatonin, a pineal hormone with antioxidant property, protects against adriamycin cardiomyopathy in rats. | Life sciences 19980101 |
Effectiveness of an antioxidant in preventing restenosis after percutaneous transluminal coronary angioplasty: the Probucol Angioplasty Restenosis Trial. | Journal of the American College of Cardiology 19971001 |
Inhibition of progression of chronic puromycin aminonucleoside nephrosis by probucol, an antioxidant. | Journal of the American Society of Nephrology : JASN 19961101 |
The mitogenic effect of H2O2 for vascular smooth muscle cells is mediated by an increase of the affinity of basic fibroblast growth factor for its receptor. | FEBS letters 19961014 |
Probucol-associated tachyarrhythmic events and QT prolongation: importance of gender. | American heart journal 19960601 |
The protective effect of probucol on adriamycin nephrosis in the rat. | Nihon Jinzo Gakkai shi 19951101 |
Currently available hypolipidaemic drugs and future therapeutic developments. | Bailliere's clinical endocrinology and metabolism 19951001 |
Copper-induced tissue factor expression in human monocytic THP-1 cells and its inhibition by antioxidants. | Circulation 19950715 |
[The ameliorative effect of probucol on adriamycin (ADR) induced nephrotic rats]. | Nihon Jinzo Gakkai shi 19950301 |
3,5-Di-t-butyl-4-hydroxytoluene (BHT) and probucol stimulate selectively the reaction of mammalian 15-lipoxygenase with biomembranes. | Biochimica et biophysica acta 19950103 |
Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect. | Circulation 19950101 |
Antihyperlipidaemic agents. Drug interactions of clinical significance. | Drug safety 19941101 |
Probucol promotes endogenous antioxidants and provides protection against adriamycin-induced cardiomyopathy in rats. | Circulation 19940601 |
Probucol-induced QT prolongation and syncope. | Japanese circulation journal 19940501 |
Propranolol for probucol-induced QT prolongation with polymorphic ventricular tachycardia. | Lancet (London, England) 19930109 |
Polymorphic ventricular tachycardia (Torsade de Pointes) associated with the use of probucol. | The New England journal of medicine 19920521 |
Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids. | Journal of medicinal chemistry 19911001 |
Ex vivo lipopolysaccharide-induced interleukin-1 secretion from murine peritoneal macrophages inhibited by probucol, a hypocholesterolemic agent with antioxidant properties. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19900401 |
Lipid-lowering agents in proteinuric diseases. | American journal of nephrology 19900101 |
Structural changes in oxidised low-density lipoproteins and of the effect of the anti-atherosclerotic drug probucol observed by synchrotron X-ray and neutron solution scattering. | European journal of biochemistry 19890801 |
Treatment of heterozygous familial hypercholesterolemia with lipid-lowering drugs. | Arteriosclerosis (Dallas, Tex.) 19890101 |
Probucol-induced QT prolongation and torsades de pointes. | Japanese journal of medicine 19890101 |
Effects of some hypolipidemic agents on biochemical values and hepatic peroxisomal enzymes in rats: comparison of probucol, CGA, KCD-232, MLM-160, AL-369 and clinofibrate with clofibrate. | Journal of pharmacobio-dynamics 19870301 |
Effect of probucol on plasma lipids and lipoproteins in type IIb hyperlipoproteinemia. | Atherosclerosis 19801101 |
Adrenergaically mediated ventricular fibrillation in probucol-treated dogs: roles of alpha and beta adrenergic receptors. | Pacing and clinical electrophysiology : PACE 19790701 |
Sensitization to epinephrine-induced ventricular fibrillation produced by probucol in dogs. | Toxicology and applied pharmacology 19730401 |