(S)-2-(2,6-Dichlorobenzamido)-3-(2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoic acid
| Title | Journal |
|---|---|
| Characterization of hepatobiliary transport systems of a novel alpha4beta1/alpha4beta7 dual antagonist, TR-14035. | Pharmaceutical research 20061101 |
| A small molecule, orally active, alpha4beta1/alpha4beta7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats. | British journal of pharmacology 20060301 |
| Role of human liver cytochrome P450 2C9 in the metabolism of a novel alpha4beta1/alpha4beta7 dual antagonist, TR-14035. | Drug metabolism and pharmacokinetics 20050401 |
| Pharmacokinetics and metabolism of TR-14035, a novel antagonist of a4ss1/a4ss7 integrin mediated cell adhesion, in rat and dog. | Xenobiotica; the fate of foreign compounds in biological systems 20050401 |
| 2,3-Diphenylpropionic acids as potent VLA-4 antagonists. | Bioorganic & medicinal chemistry letters 20050103 |
| Development of cell adhesion molecule antagonists as therapeutics for asthma and COPD. | Pulmonary pharmacology & therapeutics 20040101 |
| A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence. | The Journal of pharmacology and experimental therapeutics 20030901 |
| Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow. | The Journal of pharmacology and experimental therapeutics 20020701 |
| Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist. | Bioorganic & medicinal chemistry 20020601 |
| The discovery of sulfonylated dipeptides as potent VLA-4 antagonists. | Bioorganic & medicinal chemistry letters 20011022 |