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Xylazine HCl

CAS No.:
23076-35-9
Catalog Number:
AG002M5F
Molecular Formula:
C12H17ClN2S
Molecular Weight:
256.7948
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
>98%(HPLC)powder
In Stock USA
United States
$73
- +
100mg
>98%(HPLC)powder
In Stock USA
United States
$151
- +
Product Description
Catalog Number:
AG002M5F
Chemical Name:
Xylazine HCl
CAS Number:
23076-35-9
Molecular Formula:
C12H17ClN2S
Molecular Weight:
256.7948
MDL Number:
MFCD00058196
IUPAC Name:
N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine;hydrochloride
InChI:
InChI=1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H
InChI Key:
QYEFBJRXKKSABU-UHFFFAOYSA-N
SMILES:
Cc1cccc(c1NC1=NCCCS1)C.Cl
EC Number:
245-417-0
UNII:
NGC3S0882S
Properties
Complexity:
230  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
256.08g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
256.792g/mol
Monoisotopic Mass:
256.08g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
49.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Alfaxalone compared with ketamine for induction of anaesthesia in horses following xylazine and guaifenesin. Veterinary anaesthesia and analgesia 20121101
The effects of anesthetic regimen in 90% hepatectomy in rats. Acta cirurgica brasileira 20121001
Sufentanil citrate immobilization of Alaskan moose calves. Journal of wildlife diseases 20121001
A comparative study of xylazine-induced mechanical hypoalgesia in donkeys and horses. Veterinary anaesthesia and analgesia 20120901
Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury. Intensive care medicine 20120901
Flash responses of mouse rod photoreceptors in the isolated retina and corneal electroretinogram: comparison of gain and kinetics. Investigative ophthalmology & visual science 20120817
Gait analysis using 3D accelerometry in horses sedated with xylazine. Veterinary journal (London, England : 1997) 20120701
Comparison between the anesthetic induction times in the first and second surgery in rabbits. Acta cirurgica brasileira 20120701
The emerging of xylazine as a new drug of abuse and its health consequences among drug users in Puerto Rico. Journal of urban health : bulletin of the New York Academy of Medicine 20120601
The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma. Experimental eye research 20120601
Simultaneous determination of xylazine, free morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in postmortem blood by UPLC-MS-MS. Journal of analytical toxicology 20120601
Effects of xylazine hydrochloride on hormonal, metabolic, and cardiorespiratory stress responses to lateral recumbency and claw trimming in dairy cows. Journal of the American Veterinary Medical Association 20120515
Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury. American journal of physiology. Renal physiology 20120501
Oxygen breathing affects 3'-deoxy-3'-18F-fluorothymidine uptake in mouse models of arthritis and cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120501
The use of xylazine hydrochloride in an analgesic protocol for claw treatment of lame dairy cows in lateral recumbency on a surgical tipping table. Veterinary journal (London, England : 1997) 20120501
Comparison of the effects of xylazine bolus versus medetomidine constant rate infusion on cardiopulmonary function and depth of anesthesia in horses anesthetized with isoflurane. Journal of the American Veterinary Medical Association 20120415
Comparison of the effects of xylazine bolus versus medetomidine constant rate infusion on the stress response, urine production, and anesthetic recovery characteristics in horses anesthetized with isoflurane. Journal of the American Veterinary Medical Association 20120415
Evaluation of a midazolam-ketamine-xylazine infusion for total intravenous anesthesia in horses. American journal of veterinary research 20120401
Changes in the thalamocortical connectivity during anesthesia-induced transitions in consciousness. Neuroreport 20120328
Yohimbine antagonises α1A- and α1D-adrenoceptor mediated components in addition to the α2A-adrenoceptor component to pressor responses in the pithed rat. European journal of pharmacology 20120315
Comparison of isoflurane inhalation anaesthesia, injection anaesthesia and high volume caudal epidural anaesthesia for umbilical surgery in calves; metabolic, endocrine and cardiopulmonary effects. Veterinary anaesthesia and analgesia 20120301
Evaluation of infusions of xylazine with ketamine or propofol to modulate recovery following sevoflurane anesthesia in horses. American journal of veterinary research 20120301
Simultaneous HPLC-UV determination of ketamine, xylazine, and midazolam in canine plasma. Journal of chromatographic science 20120201
Antiemetic efficacy of promethazine on xylazine-induced emesis in cats. The Canadian veterinary journal = La revue veterinaire canadienne 20120201
Development of a xylazine constant rate infusion with or without butorphanol for standing sedation of horses. Veterinary anaesthesia and analgesia 20120101
Field immobilization of Molina's hog-nosed skunk (Conepatus chinga) using ketamine and xylazine. Journal of wildlife diseases 20120101
Inhibition of firefly luciferase by general anesthetics: effect on in vitro and in vivo bioluminescence imaging. PloS one 20120101
Assessment of xylazine for euthanasia of anoles (Anolis carolinensis and Anolis distichus). Journal of the American Association for Laboratory Animal Science : JAALAS 20120101
Visualization of murine intranasal dosing efficiency using luminescent Francisella tularensis: effect of instillation volume and form of anesthesia. PloS one 20120101
Qualitative and quantitative characteristics of the electroencephalogram in normal horses after sedation. Journal of veterinary internal medicine 20120101
Effects of combined ketamine/xylazine anesthesia on light induced retinal degeneration in rats. PloS one 20120101
Ischemia-reperfusion injury of the mouse kidney. Methods in molecular biology (Clifton, N.J.) 20120101
[Comparison of three different anesthesia procedures in calves with respect to possible pain-associated reactions]. Berliner und Munchener tierarztliche Wochenschrift 20120101
Haematological and biochemical alterations caused by epidural and intramuscular administration of xylazine hydrochloride in dromedary camels (Camelus dromedarius). Veterinaria italiana 20120101
GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses. British journal of pharmacology 20111201
Serum clearance of iodixanol for estimating glomerular filtration rate in calves. The Journal of veterinary medical science 20111201
Anesthesia of Tibetan yak (Bos grunniens) using thiafentanil - xylazine and carfentanil - xylazine. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20111201
Surrogate data modeling the relationship between high frequency amplitudes and Higuchi fractal dimension of EEG signals in anesthetized rats. Journal of theoretical biology 20111121
The 'other' respiratory effect of opioids: suppression of spontaneous augmented ('sigh') breaths. Journal of applied physiology (Bethesda, Md. : 1985) 20111101
Properties of slow oscillation during slow-wave sleep and anesthesia in cats. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019
Synaptic action of the olivocerebellar system on cerebellar nuclear spike activity. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111012
Transient effects of anesthetics on dendritic spines and filopodia in the living mouse cortex. Anesthesiology 20111001
Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation. Anesthesiology 20111001
Comparison of xylazine-butorphanol and xylazine-morphine-ketamine infusions in horses undergoing a standing surgery. The Veterinary record 20111001
Pharmacokinetics and physiologic effects of intramuscularly administered xylazine hydrochloride-ketamine hydrochloride-butorphanol tartrate alone or in combination with orally administered sodium salicylate on biomarkers of pain in Holstein calves following castration and dehorning. American journal of veterinary research 20111001
The pharmacokinetics and pharmacodynamics of the injectable anaesthetic alfaxalone in the horse. Veterinary anaesthesia and analgesia 20110901
Sedative and analgesic effects of intravenous xylazine and tramadol on horses. Journal of veterinary science 20110901
[Comparison of the effects of xylazine and romifidine administered perioperatively on the recovery of anesthetized horses]. The Canadian veterinary journal = La revue veterinaire canadienne 20110901
Comparison of carfentanil-xylazine and thiafentanil-medetomidine in electroejaculation of captive gaur (Bos gaurus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20110901
Estimation of electrode location in a rat motor cortex by laminar analysis of electrophysiology and intracortical electrical stimulation. Journal of neural engineering 20110801
Cardiovascular effects of N-butylscopolammonium bromide and xylazine in horses. Equine veterinary journal. Supplement 20110801
The effect of sedation on D(+)-xylose absorption tests in 6 normal horses. Equine veterinary journal. Supplement 20110801
Antagonistic effect of atipamezole, flumazenil and naloxone following anaesthesia with xylazine, tramadol and tiletamine/zolazepam combinations in pigs. Veterinary anaesthesia and analgesia 20110701
Sufentanil and xylazine immobilization of Rocky Mountain elk. Journal of wildlife diseases 20110701
In vitro and in vivo responses of mucosa from the large colon of horses to ischemia and reperfusion. American journal of veterinary research 20110701
Sudden hind limb injuries in two rabbits. Self-mutilation after intramuscular ketamine-related neuronal injury. Lab animal 20110621
Evaluation of sedation and analgesia in standing horses after administration of xylazine, butorphanol, and subanesthetic doses of ketamine. Journal of the American Veterinary Medical Association 20110615
Xylazine-/diazepam-ketamine and isoflurane differentially affect hemodynamics and organ injury under hemorrhagic/traumatic shock and resuscitation in rats. Shock (Augusta, Ga.) 20110601
Effect of general anesthetics on IOP in elevated IOP mouse model. Experimental eye research 20110601
Effects of common anesthetics on eye movement and electroretinogram. Documenta ophthalmologica. Advances in ophthalmology 20110601
Serum biochemical values of adult ostriches (Struthio camelus) anesthetized with xylazine, ketamine, and isoflurane. Journal of avian medicine and surgery 20110601
Assessment of parameters influencing the blood flow velocities in cerebral arteries of the rat using ultrasonographic examination. Neurological research 20110501
Effect of a short-term fast on ketamine-xylazine anesthesia in rats. Journal of the American Association for Laboratory Animal Science : JAALAS 20110501
High doses of ketamine-xylazine anesthesia reduce cardiac ischemia-reperfusion injury in guinea pigs. Journal of the American Association for Laboratory Animal Science : JAALAS 20110501
Analgesic effects of meloxicam, morphine sulfate, flunixin meglumine, and xylazine hydrochloride in African-clawed frogs (Xenopus laevis). Journal of the American Association for Laboratory Animal Science : JAALAS 20110501
Liquid chromatography-tandem mass spectrometry detection of the quaternary ammonium compound mebezonium as an active ingredient in t61. Journal of analytical toxicology 20110301
Deep anesthesia suppresses ventricular tachyarrhythmias in rabbit model of the acquired long QT syndrome. Circulation journal : official journal of the Japanese Circulation Society 20110101
The effect of vitamin C at varying times on physiological parameters in rabbits after xylazine anaesthesia. Veterinaria italiana 20110101
Sedative and cardiopulmonary effects of buprenorphine and xylazine in horses. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20110101
Xylazine (veterinary sedative) use in Puerto Rico. Substance abuse treatment, prevention, and policy 20110101
Immobilization of muskoxen (Ovibos moschatus) with etorphine and xylazine. Acta veterinaria Scandinavica 20110101
Influence of modified open lung concept ventilation on the cardiovascular and pulmonary function of horses during total intravenous anaesthesia. The Veterinary record 20101225
Cardiopulmonary effects of dorsal recumbency and high-volume caudal epidural anaesthesia with lidocaine or xylazine in calves. Veterinary journal (London, England : 1997) 20101201
Effects of metoclopramide on emesis in cats sedated with xylazine hydrochloride. Journal of feline medicine and surgery 20101201
Effect of sub-anesthetic xylazine and ketamine ('ketamine stun') administered to calves immediately prior to castration. Veterinary anaesthesia and analgesia 20101101
Comparison of ketamine-diazepam with ketamine-xylazine anesthetic combinations in sheep spontaneously breathing and undergoing maxillofacial surgery. Bosnian journal of basic medical sciences 20101101
Ketamine-xylazine anesthesia causes hyperopic refractive shift in mice. Journal of neuroscience methods 20101030
The effects of anesthesia on measures of nerve conduction velocity in male C57Bl6/J mice. Neuroscience letters 20101011
Total intravenous anesthesia with midazolam, ketamine, and xylazine or detomidine following induction with tiletamine, zolazepam, and xylazine in red deer (Cervus elaphus hippelaphus) undergoing surgery. Journal of wildlife diseases 20101001
Comparison of chemical immobilization methods in wild foxes (Pseudalopex griseus and Pseudalopex culpaeus) in Chile. Journal of wildlife diseases 20101001
Effect of the addition of tramadol to a combination of tiletamine-zolazepam and xylazine for anaesthesia of miniature pigs. The Veterinary record 20100925
Duration of anesthesia affects intraocular pressure, but not outflow facility in mice. Current eye research 20100901
Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury. Shock (Augusta, Ga.) 20100901
Comparison of thiafenantil-xylazine and carfentanil-xylazine for immobilization of gemsbok (Oryx gazella). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20100901
Comparison of anaesthetic and cardiorespiratory effects of xylazine or medetomidine in combination with tiletamine/zolazepam in pigs. The Veterinary record 20100814
Electro-acupuncture reduces the need for additional anesthetics in experimental studies. Acta cirurgica brasileira 20100801
Sympathetic modulation of the host defense response to infectious challenge during recovery from hemorrhage. Neuroimmunomodulation 20100701
Effects of ketamine-xylazine intravenous bolus injection on cardiovascular function in rabbits. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20100701
Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia. European journal of pharmacology 20100610
Use of xylazine hydrochloride-ketamine hydrochloride for immobilization of wild leopards (Panthera pardus fusca) in emergency situations. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20100601
Comparison of three anaesthetic protocols in Bennett's wallabies (Macropus rufogriseus). Veterinary anaesthesia and analgesia 20100501
Euthanasia by CO₂ inhalation affects potassium levels in mice. Journal of the American Association for Laboratory Animal Science : JAALAS 20100501
The forced walking test: a novel test for pinpointing the anesthetic-induced transition in consciousness in mouse. Journal of neuroscience methods 20100430
Action of a Novel PDE4 inhibitor ZL-n-91 on lipopolysaccharide-induced acute lung injury. International immunopharmacology 20100401
Experimental xylazine-ketamine anesthesia in the common carp (Cyprinus carpio). Journal of wildlife diseases 20100401
Rat model of influenza-associated encephalopathy (IAE): studies of electroencephalogram (EEG) in vivo. Neuroscience 20100217
Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [3H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia. European journal of pharmacology 20100210
Effect of hot-iron disbudding on behaviour and plasma cortisol of calves sedated with xylazine. Research in veterinary science 20100201
Effects of anesthetic agents on socially transmitted olfactory memories in mice. Neurobiology of learning and memory 20100201
Effects of ciclosporin therapy on xylazine/ketamine anaesthesia in a rat model. Journal of veterinary pharmacology and therapeutics 20100201
The relative stability of xylazine hydrochloride polymorphous forms. Pharmaceutical development and technology 20100101
Topical mydriatics affect light-evoked retinal responses in anesthetized mice. Investigative ophthalmology & visual science 20100101
Porcine vas deferens luminal pH is acutely increased by systemic xylazine administration. Biology of reproduction 20100101
Antinociceptive, sedative and cardiopulmonary effects of subarachnoid and epidural xylazine-lidocaine in xylazine-sedated calves. Veterinary anaesthesia and analgesia 20100101
Use of hyaluronidase to improve chemical immobilization of free-ranging polar bears (Ursus maritimus). Journal of wildlife diseases 20100101
Ketamine-xylazine-acepromazine compared with isoflurane for anesthesia during liver transplantation in rodents. Journal of the American Association for Laboratory Animal Science : JAALAS 20100101
Effect of acepromazine or xylazine on tear production as measured by Schirmer tear test in normal cats. Veterinary ophthalmology 20100101
Effects of anesthetic protocol on normal canine brain uptake of 18F-FDG assessed by PET/CT. Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 20100101
Tachypnea and antipyresis in febrile horses after sedation with alpha-agonists. Journal of veterinary internal medicine 20100101
Description of the type of chemical restraint used by French veterinarians to perform hip dysplasia screening radiographs. A retrospective study based on 3302 radiographs. Veterinary and comparative orthopaedics and traumatology : V.C.O.T 20100101
Impaired growth and force production in skeletal muscles of young partially pancreatectomized rats: a model of adolescent type 1 diabetic myopathy? PloS one 20100101
Bevacizumab accelerates corneal wound healing by inhibiting TGF-beta2 expression in alkali-burned mouse cornea. BMB reports 20091231
Reversal of ketamine/xylazine combination anesthesia by atipamezole in olive baboons (Papio anubis). Journal of medical primatology 20091201
Effective reduced diffusion-models: a data driven approach to the analysis of neuronal dynamics. PLoS computational biology 20091201
Use of propofol-xylazine and the Anderson Sling Suspension System for recovery of horses from desflurane anesthesia. Veterinary surgery : VS 20091201
Involvement of ATP-sensitive K(+) channels in the peripheral antinociceptive effect induced by the alpha(2)-adrenoceptor agonist xylazine. Journal of pharmacological sciences 20091201
Effects of different general anesthetics on serum hemolysis and hepatic and muscular glycogenolysis in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091101
Tramadol improved the efficacy of ketamine-xylazine anaesthesia in young pigs. Veterinary anaesthesia and analgesia 20091101
Physiologic effects of electroacupuncture combined with intramuscular administration of xylazine to provide analgesia in goats. American journal of veterinary research 20091101
Beyond-use dating of extemporaneously compounded ketamine, acepromazine, and xylazine: safety, stability, and efficacy over time. Journal of the American Association for Laboratory Animal Science : JAALAS 20091101
Comparison of the effects of three different combinations of general anesthetics on the electroretinogram of dogs. Documenta ophthalmologica. Advances in ophthalmology 20091001
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
Alpha2-adrenergic impact on hypothalamic magnocellular oxytocinergic neurons in long evans and brattleboro rats: effects of agonist and antagonists. Cellular and molecular neurobiology 20090901
A comparison of subarachnoid buprenorphine or xylazine as an adjunct to lidocaine for analgesia in goats. Veterinary anaesthesia and analgesia 20090901
Standardization of some electrocardiographic parameters of captive leopard cats (Leopardus tigrinus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20090901
Euthanasia method for mice in rapid time-course pulmonary pharmacokinetic studies. Journal of the American Association for Laboratory Animal Science : JAALAS 20090901
Effects of midazolam on ketamine-xylazine anesthesia in guinea fowl (Numida meleagris galeata). Journal of avian medicine and surgery 20090901
Effect of administration of propofol and xylazine hydrochloride on recovery of horses after four hours of anesthesia with desflurane. American journal of veterinary research 20090801
Comparison of the effects of the alpha-2 agonists detomidine, romifidine and xylazine on nociceptive withdrawal reflex and temporal summation in horses. Veterinary anaesthesia and analgesia 20090701
Diuretic effects of medetomidine compared with xylazine in healthy dogs. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20090701
alpha(2)-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the L-arginine/nitric oxide/cyclic GMP pathway in rat. European journal of pharmacology 20090624
Ketamine/xylazine anesthesia alters [11C]MNPA binding to dopamine D2 receptors and response to methamphetamine challenge in monkey brain. Synapse (New York, N.Y.) 20090601
The use of xylazine, ketamine, and isoflurane for induction and maintenance of anesthesia in ostriches (Struthio camelus). Journal of avian medicine and surgery 20090601
Effects of lumbosacral epidural ketamine and lidocaine in xylazine-sedated cats. Journal of the South African Veterinary Association 20090601
Use of two anesthetic combinations for semen collection by electroejaculation from captive coatis (Nasua nasua). Theriogenology 20090501
Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction. American journal of physiology. Heart and circulatory physiology 20090501
Cardiopulmonary effects of diazepam-ketamine-isoflurane or xylazine-ketamine-isoflurane during abdominal surgery in foals. American journal of veterinary research 20090501
Antagonistic effects of atipamezole and yohimbine on xylazine-induced diuresis in healthy dogs. The Journal of veterinary medical science 20090501
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine. European journal of pharmacology 20090417
Pharmacokinetics of ketamine and its metabolite norketamine administered at a sub-anesthetic dose together with xylazine to calves prior to castration. Journal of veterinary pharmacology and therapeutics 20090401
Colour-Doppler sonography of the musculophrenic vein in cows. Veterinary journal (London, England : 1997) 20090301
Physiologic effects of nasal oxygen or medical air administered prior to and during carfentanil-xylazine anesthesia in North American elk (Cervus canadensis manitobensis). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20090301
Short-term anaesthesia with xylazine, diazepam/ketamine for castration in horses under field conditions: use of intravenous lidocaine. Equine veterinary journal 20090201
Vascular perfusion of reproductive organs in pony mares and heifers during sedation with detomidine or xylazine. American journal of veterinary research 20090101
Effects of changing body position on oxygenation and arterial blood pressures in foals anesthetized with guaifenesin, ketamine, and xylazine. Veterinary anaesthesia and analgesia 20090101
Yohimbine antagonizes the anaesthetic effects of ketamine-xylazine in captive Indian wild felids. Veterinary anaesthesia and analgesia 20090101
Effect of bupivacaine on epidural analgesia produced by xylazine or medetomidine in buffaloes (Bubalus bubalis). Veterinary anaesthesia and analgesia 20090101
Cerebral injury from intracarotid injection in an alpaca (Vicugna pacos). Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20090101
Assessment of serum enzymatic markers of cardiomyocytes injury in female dogs submitted to ketamine S(+), atropin and xylazine association. Acta cirurgica brasileira 20090101
An effective venipuncture technique and normal serum biochemistry parameters of the captive fat-tailed jird (Pachyuromys duprasi). Journal of the American Association for Laboratory Animal Science : JAALAS 20090101
Hydration and dehydration kinetics of xylazine hydrochloride. Pharmaceutical development and technology 20090101
A modified suture technique produces consistent cerebral infarction in rats. Brain research 20081230
Ketamine and xylazine combinations for short-term immobilization of wild variable flying foxes (Pteropus hypomelanus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20081201
Increasing ketamine dose enhances the anaesthetic properties of ketamine-xylazine-midazolam combinations in growing pigs. Journal of the South African Veterinary Association 20081201
Effects of methadone, alone or in combination with acepromazine or xylazine, on sedation and physiologic values in dogs. Veterinary anaesthesia and analgesia 20081101
Efficacy and safety of five injectable anesthetic regimens for chronic blood collection from the anterior vena cava of Guinea pigs. Journal of the American Association for Laboratory Animal Science : JAALAS 20081101
Repeated anaesthesia with isoflurane and xylazine/levomethadone/fenpipramide premedication in female Beagle dogs: influence on general health and wellbeing. Laboratory animals 20081001
The effect of ketamine/xylazine and carbon dioxide on plasma luteinizing hormone releasing hormone and testosterone concentrations in the male Norway rat. Laboratory animals 20081001
Stereoselective pharmacokinetics of ketamine and norketamine after racemic ketamine or S-ketamine administration in Shetland ponies sedated with xylazine. Veterinary journal (London, England : 1997) 20080901
Electrocardiographic parameters of captive lions (Panthera leo) and tigers (Panthera tigris) immobilized with ketamine plus xylazine. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20080901
Thermal, cardiorespiratory and cortisol responses of impala (Aepyceros melampus) to chemical immobilisation with 4 different drug combinations. Journal of the South African Veterinary Association 20080901
Immobilising free-ranging Alpine chamois with xylazine, reversed with atipamezole. The Veterinary record 20080809
GC-MS confirmation of xylazine (Rompun), a veterinary sedative, in exchanged needles. Drug and alcohol dependence 20080801
B-mode and colour Doppler ultrasonography of the milk vein in 29 healthy Swiss braunvieh cows. The Veterinary record 20080712
To catch a buffalo: field immobilisation of Asian swamp buffalo using etorphine and xylazine. Australian veterinary journal 20080601
The effects of anesthesia with a combination of intramuscular xylazine-diazepam-ketamine on heart rate, respiratory rate and cloacal temperature in roosters. Veterinary anaesthesia and analgesia 20080501
A comparison of two combinations of xylazine-ketamine administered intramuscularly to alpacas and of reversal with tolazoline. Veterinary anaesthesia and analgesia 20080501
Cytochrome P450 2E1 in the substantia nigra: relevance for dopaminergic neurotransmission and free radical production. Synapse (New York, N.Y.) 20080501
Rebound tonometry in conscious, conditioned mice avoids the acute and profound effects of anesthesia on intraocular pressure. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080401
Neurohormonal and metabolic effects of medetomidine compared with xylazine in healthy cats. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20080401
Brainstem auditory evoked potentials in cattle sedated with xylazine. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20080401
Stable in vivo imaging of densely populated glia, axons and blood vessels in the mouse spinal cord using two-photon microscopy. Journal of neuroscience methods 20080330
A comparison of equine recovery characteristics after isoflurane or isoflurane followed by a xylazine-ketamine infusion. Veterinary anaesthesia and analgesia 20080301
Comparative study of epidural xylazine or clonidine in horses. Veterinary anaesthesia and analgesia 20080301
Concurrent detection of heroin, fentanyl, and xylazine in seven drug-related deaths reported from the Philadelphia Medical Examiner's Office. Journal of forensic sciences 20080301
Sedative and cardiopulmonary effects of medetomidine hydrochloride and xylazine hydrochloride and their reversal with atipamezole hydrochloride in calves. American journal of veterinary research 20080301
alpha2B-adrenoceptor agonist ST-91 antagonizes beta2-adrenoceptor-mediated relaxation in rat mesenteric artery rings. European journal of pharmacology 20080212
Plasma glucose concentration is maintained during TSE infection of cattle and sheep. Veterinary research communications 20080201
Alpha-2 agonists decrease expression of morphine-induced conditioned place preference. Pharmacology, biochemistry, and behavior 20080201
Effects of anesthesia on DPOAE level and phase in rats. Hearing research 20080101
Safety and efficacy of various combinations of injectable anesthetics in BALB/c mice. Journal of the American Association for Laboratory Animal Science : JAALAS 20080101
Effects of two different anaesthetics on serum concentrations of cortisol and luteinizing hormone in barrows and gilts. Laboratory animals 20080101
Pharmacological restraint of captivity giant Amazonian turtle Podocnemis expansa (Testudines, Podocnemididae) with xylazine and propofol. Acta cirurgica brasileira 20080101
The maintained discharge of rat retinal ganglion cells. Visual neuroscience 20080101
Use of ketamine, xylazine, and diazepam anesthesia with retrobulbar block for phacoemulsification in dogs. Veterinary ophthalmology 20080101
Anaesthesia generates neuronal insulin resistance by inducing hypothermia. BMC neuroscience 20080101
The effect of general anesthesia on the intestinal lymphatic transport of lipophilic drugs: comparison between anesthetized and freely moving conscious rat models. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20071201
Cardiopulmonary effects of administration of a combination solution of xylazine, guaifenesin, and ketamine or inhaled isoflurane in mechanically ventilated calves. American journal of veterinary research 20071201
Comparison of quality of induction of anaesthesia between intramuscularly administered ketamine, intravenously administered ketamine and intravenously administered propofol in xylazine premedicated cats. Journal of the South African Veterinary Association 20071201
Antagonistic effects of yohimbine in pigs anaesthetised with tiletamine/zolazepam and xylazine. The Veterinary record 20071103
Effects of anesthetic agents on serum parathyroid hormone and calcium concentrations in mice. Veterinary anaesthesia and analgesia 20071101
Isoflurane is an effective alternative to ketamine/xylazine/acepromazine as an anesthetic agent for the mouse electroretinogram. Documenta ophthalmologica. Advances in ophthalmology 20071101
Interaction of anaesthetic drugs and UV-B irradiation in the anterior segment of the rat eye. Acta ophthalmologica Scandinavica 20071101
Outcome of medical and surgical treatment of cecal impaction in horses: 114 cases (1994-2004). Journal of the American Veterinary Medical Association 20071101
Tiletamine-zolazepam and xylazine is a potent cardiodepressive combination: a case report. Journal of the American Association for Laboratory Animal Science : JAALAS 20071101
Clinicophysiological effects of spinally administered ketamine and its combination with xylazine and medetomidine in healthy goats. Veterinary research communications 20071001
Determination of sensitivity of male Wistar rats to an equal dose of ketamine/xylazine injection at anesthetic dose in a chronic model of hypernatremia in comparison with control group. Saudi medical journal 20071001
Ketamine and xylazine depress sensory-evoked parallel fiber and climbing fiber responses. Journal of neurophysiology 20070901
Heroin: what's in the mix? Annals of emergency medicine 20070901
High caudal epidural anaesthesia with local anaesthetics or alpha(2)-agonists in calves. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20070901
The use of alpha-2 agonists in the equine practice: comparison between three molecules. Veterinary research communications 20070801
Effects of NMDA receptor antagonists on visceromotor reflexes and on intestinal motility, in vivo. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070701
Successful introduction of modified dorsolumbar epidural anesthesia in a bovine referral center. Journal of veterinary science 20070601
Xylazine premedication does not modify the onset and duration of cisatracurium blockade in anaesthetized dogs. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20070601
Arthrotomy and arthrodesis of the fetlock joint in cattle. The Veterinary record 20070519
Influence of the mode of ventilation on ketamine/xylazine requirements in rabbits. Veterinary anaesthesia and analgesia 20070501
Interactions between cardiac, respiratory and EEG-delta oscillations in rats during anaesthesia. The Journal of physiology 20070401
Tiletamine-zolazepam-xylazine immobilization of fishers (Martes pennanti). Journal of wildlife diseases 20070401
Solid-phase extraction and gas chromatographic- mass spectrometric determination of the veterinary drug xylazine in human blood. Journal of analytical toxicology 20070401
Impact of sedation method on the diagnosis of hip and elbow dysplasia in Swedish dogs. Preventive veterinary medicine 20070317
Strategies for refinement of abdominal device implantation in mice: strain, carboxymethylcellulose, thermal support, and atipamezole. Journal of the American Association for Laboratory Animal Science : JAALAS 20070301
Comparison of cardiovascular effects of tiletamine-zolazepam, pentobarbital, and ketamine-xylazine in male rats. Journal of the American Association for Laboratory Animal Science : JAALAS 20070301
Effects of epidural ketamine-xylazine combination on the clinicophysiological and haematobiochemical parameters of uraemic and healthy goats. Veterinary research communications 20070201
Effects of anesthesia on echocardiographic assessment of left ventricular structure and function in rats. Basic research in cardiology 20070101
Influence of different anesthetics on skin oxygenation studied by electron paramagnetic resonance in vivo. Skin pharmacology and physiology 20070101
Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination. Physiological research 20070101
Anesthesia induced by administration of xylazine hydrochloride alone or in combination with ketamine hydrochloride and reversal by administration of yohimbine hydrochloride in captive Axis deer (Axis axis). American journal of veterinary research 20070101
Neuroprotective effect of ketamine/xylazine on two rat models of Parkinson's disease. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070101
Optimizing dosage of ketamine and xylazine in murine echocardiography. Clinical and experimental pharmacology & physiology 20070101
Xylazine abuse: a rare cause of syncope. Clinical toxicology (Philadelphia, Pa.) 20070101
Anti-emetic effect of oculo-acupuncture on dogs with xylazine induced vomiting. The American journal of Chinese medicine 20070101
Comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-butorphanol and tiletamine-zolazepam-butorphanol-medetomidine in dogs. Veterinary therapeutics : research in applied veterinary medicine 20070101
Continuous infusion in adult females dogs submitted to ovariohysterectomy with midazolam-xylazine and/or medetomidine pre-treated with methotrimeprazine and buprenorphine. Acta cirurgica brasileira 20070101
A comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-butorphanol and tiletamine-zolazepam-butorphanol- medetomidine in cats. Veterinary therapeutics : research in applied veterinary medicine 20070101
Influence of dosage and chemical restraints on feline excretory urography. Journal of the South African Veterinary Association 20061201
Characterization of the antinociceptive and anti-inflammatory activities of riboflavin in different experimental models. European journal of pharmacology 20061010
Xylazine promotes axonal regeneration in the crushed optic nerve of adult rats. Neuroreport 20061002
Xylazine, ketamine and their combination for lumbar epidural analgesia in water buffalo calves (Bubalus bubalis). Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20061001
Differential effects of chloral hydrate- and ketamine/xylazine-induced anesthesia by the s.c. route. Life sciences 20060920
Effects of ketamine on carfentanil and xylazine immobilization of white-tailed deer (Odocoileus virginianus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20060901
Nitric oxide induced by ketamine/xylazine anesthesia maintains hepatic blood flow during hypothermia. Nitric oxide : biology and chemistry 20060801
Euthanasia of exotic pigs. The Veterinary record 20060701
Refractometry for quality control of anesthetic drug mixtures. Journal of the American Association for Laboratory Animal Science : JAALAS 20060701
[Use of hyaluronic acid cleaving enzymes for absorption acceleration. Results of an in vitro study with xylazine and ketamine]. DTW. Deutsche tierarztliche Wochenschrift 20060701
Immobilization of Himalayan tahr with a xylazine-ketamine mixture and reversal with atipamezole under field conditions. Journal of wildlife diseases 20060701
Frequency-current relationships of rat hindlimb alpha-motoneurones. The Journal of physiology 20060615
Stress associated with road transportation in desert sheep and goats, and the effect of pretreatment with xylazine or sodium betaine. Research in veterinary science 20060601
Effects of xylazine, medetomidine, detomidine, and diazepam on sedation, heart and respiratory rates, and cloacal temperature in rock partridges (Alectoris graeca). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20060601
Clinical evaluation of intranasal benzodiazepines, alpha-agonists and their antagonists in canaries. Veterinary anaesthesia and analgesia 20060501
Systemic toxicity after an ocular exposure to xylazine hydrochloride. The Journal of emergency medicine 20060501
The use of impulse oscillometry for separate analysis of inspiratory and expiratory impedance parameters in horses: effects of sedation with xylazine. Research in veterinary science 20060401
Multiple centrally acting antidotes protect against severe organophosphate toxicity. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20060401
Fluphenazine-induced extrapyramidal side effects in a horse. The Veterinary clinics of North America. Equine practice 20060401
The influence of butorphanol dose on characteristics of xylazine-butorphanol-propofol anesthesia in horses at altitude. Veterinary anaesthesia and analgesia 20060301
Ketamine-xylazine-acepromazine anesthesia and postoperative recovery in rats. Journal of the American Association for Laboratory Animal Science : JAALAS 20060301
Xylazine, diazepam and midazolam premedicated ketamine anaesthesia in white Leghorn cockerels for typhlectomy. Journal of the South African Veterinary Association 20060301
Sedative effects of midazolam and xylazine with or without ketamine and detomidine alone following intranasal administration in Ring-necked Parakeets. Journal of the American Veterinary Medical Association 20060201
Parametric evaluation of methotrimeprazine-midazolam-ketamine and methotrimeprazine-midazolam-ketamine-xylazine combination in dogs. Acta cirurgica brasileira 20060101
Xylazine activates oxytocinergic but not vasopressinergic hypothalamic neurons under normal and hyperosmotic conditions in rats. Neurochemistry international 20051201
Stress hormones: a link between maternal condition and sex-biased reproductive investment. The American naturalist 20051201
Acid-base, blood gas, and physiologic parameters during laparoscopy in the head-down position in white-tailed deer (Odocoileus virginianus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20051201
Acute hyperglycemia induced by ketamine/xylazine anesthesia in rats: mechanisms and implications for preclinical models. Experimental biology and medicine (Maywood, N.J.) 20051101
The sulfonylurea glipizide does not inhibit ischemic preconditioning in anesthetized rabbits. Cardiovascular drugs and therapy 20051001
Comparative study of three intramuscular anaesthetic combinations (medetomidine/ketamine, medetomidine/fentanyl/midazolam and xylazine/ketamine) in rabbits. Veterinary anaesthesia and analgesia 20050901
The analgesic effects of intrathecal xylazine and detomidine in sheep and their antagonism with systemic atipamezole. Veterinary anaesthesia and analgesia 20050901
Ischemic brain damage after ketamine and xylazine treatment in a young laboratory monkey (Macaca fascicularis). Contemporary topics in laboratory animal science 20050901
Determination of acepromazine, ketamine, medetomidine, and xylazine in serum: multi-residue screening by liquid chromatography-mass spectrometry. Journal of analytical toxicology 20050901
Preferable anesthetic conditions for echocardiographic determination of murine cardiac function. Journal of pharmacological sciences 20050901
Epidural administration of fixed volumes of xylazine and lidocaine for anesthesia of dairy cattle undergoing flank surgery. Journal of the American Veterinary Medical Association 20050901
Effects of xylazine, lignocaine and their combination for lumber epidural analgesia in water buffalo calves (Bubalus bubalis). Journal of the South African Veterinary Association 20050901
Comparison of xylazine and medetomidine as premedicants for cats being anaesthetised with propofol-sevoflurane. The Veterinary record 20050730
Determination and evaluation of an optimal dosage of carfentanil and xylazine for the immobilization of white-tailed deer (Odocoileus virginianus). Journal of wildlife diseases 20050701
Tiletamine-zolazepam-xylazine immobilization of American marten (Martes americana). Journal of wildlife diseases 20050701
Variable coupling between olfactory system activity and respiration in ketamine/xylazine anesthetized rats. Journal of neurophysiology 20050601
The minimum infusion rate (MIR) of propofol for total intravenous anesthesia after premedication with xylazine in horses. The Journal of veterinary medical science 20050601
Duplex ultrasonography of the common carotid artery and external jugular vein of cows. American journal of veterinary research 20050601
Evaluation of xylazine and ketamine for total intravenous anesthesia in horses. American journal of veterinary research 20050601
Analgesic and systemic effects of xylazine, lidocaine and their combination after subarachnoid administration in goats. Journal of the South African Veterinary Association 20050601
Clinical evaluation of caudal epidural anaesthesia for the neutering of alpacas. The Veterinary record 20050507
Dehorning and disbudding distress and its alleviation in calves. Veterinary journal (London, England : 1997) 20050501
[Immobilization of cattle and bison with a combination of xylazine, zolazepam-tiletamine and ketamine]. Tijdschrift voor diergeneeskunde 20050501
Calf response to caustic paste and hot-iron dehorning using sedation with and without local anesthetic. Journal of dairy science 20050401
Influence of general anesthesia on pharmacokinetics of intravenous lidocaine infusion in horses. American journal of veterinary research 20050401
Efficacy of immobilizing free-ranging elk with Telazol and xylazine hydrochloride using transmitter-equipped darts. Journal of wildlife diseases 20050401
Myocardial blood flow mapping in mice using high-resolution spin labeling magnetic resonance imaging: influence of ketamine/xylazine and isoflurane anesthesia. Magnetic resonance in medicine 20050301
Increases in extracellular fluid glucose levels in the rat hippocampus following an anesthetic dose of pentobarbital or ketamine-xylazine: an in vivo microdialysis study. Physiology & behavior 20050215
Importance of anesthesia for the genesis of neurogenic pulmonary edema in spinal cord injury. Neuroscience letters 20050110
Low-dose anesthesia for corneal transplantation in mice. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050101
Colorectal distention in the horse: visceral sensitivity, rectal compliance and effect of i.v. xylazine or intrarectal lidocaine. Equine veterinary journal 20050101
Levels of glutathione peroxidase, lipoperoxidase and some biochemical and haematological parameters in gazelles anaesthetised with a tiletamin-zolazepam-xylazine combination. Veterinary journal (London, England : 1997) 20050101
Efficacy and safety of stored and newly prepared tribromoethanol in ICR mice. Contemporary topics in laboratory animal science 20050101
Echocardiographic variables in healthy guineapigs anaesthetized with ketamine-xylazine. Laboratory animals 20050101
Isolation stress in desert sheep and goats and the influence of pretreatment with xylazine or sodium betaine. Veterinary research communications 20050101
Immobilization (restraint) stress in desert sheep and goats, and the influence of pretreatment with xylazine or sodium betaine thereon. Polish journal of veterinary sciences 20050101
Granule cells in the cochlear nucleus sensitive to sound activation detected by Fos protein expression. Neuroscience 20050101
Effect of age and abomasal puncture on peritoneal fluid, hematology, and serum biochemical analyses in young calves. Journal of veterinary internal medicine 20050101
Synaptic enhancement induced through callosal pathways in cat association cortex. Journal of neurophysiology 20041201
An unusual presentation from xylazine-ketamine. Veterinary and human toxicology 20041201
Cine-MRI assessment of cardiac function in mice anesthetized with ketamine/xylazine and isoflurane. Magma (New York, N.Y.) 20041201
Comparison of xylazine, lidocaine and the two drugs combined for modified dorsolumbar epidural anaesthesia in cattle. The Veterinary record 20041201
Ketamine/xylazine anesthesia for radiologic imaging of neurologically impaired rats: dose response, respiratory depression, and management of complications. Comparative medicine 20041201
Experimental autoimmune encephalomyelitis (EAE): lesion visualization on a 3 Tesla clinical whole-body system after intraperitoneal contrast injection. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20041101
Multiresidue method for the detection of tranquillisers, xylazine, and a beta-blocker in animal production by liquid chromatography-tandem mass spectrometry. Journal of chromatography. A 20041029
Effects of anesthetics on systemic hemodynamics in mice. American journal of physiology. Heart and circulatory physiology 20041001
Anesthetic and physiologic effects of tiletamine, zolazepam, ketamine, and xylazine combination (TKX) in feral cats undergoing surgical sterilization. Journal of feline medicine and surgery 20041001
Effects of alpha2-adrenergic receptor agonists on urine production in horses deprived of food and water. American journal of veterinary research 20041001
Cardiopulmonary effects of romifidine/ketamine or xylazine/ketamine when used for short duration anesthesia in the horse. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20041001
Field immobilization of raccoons (Procyon lotor) with Telazol and xylazine. Journal of wildlife diseases 20041001
Effect of anesthesia on the signal intensity in tumors using BOLD-MRI: comparison with flow measurements by Laser Doppler flowmetry and oxygen measurements by luminescence-based probes. Magnetic resonance imaging 20040901
Chemical immobilization of rhebok (Pelea capreolus) with carfentanil-xylazine or etorphine-xylazine. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20040901
Xylazine-midazolam-ketamine versus medetomidine-midazolam-ketamine anesthesia in captive Siberian tigers (Panthera tigris altaica). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20040901
Cardiorespiratory effects of diazepam-ketamine, xylazine-ketamine and thiopentone anesthesia in male Wistar rats--a comparative analysis. Life sciences 20040827
Energetic cost of breathing, body composition, and pulmonary function in horses with recurrent airway obstruction. Journal of applied physiology (Bethesda, Md. : 1985) 20040701
Impact of conventional anesthesia on auditory brainstem responses in mice. Hearing research 20040701
Effectiveness of antagonists for tiletamine-zolazepam/xylazine immobilization in female white-tailed deer. Journal of wildlife diseases 20040701
Intranasal administration of xylazine to reduce stress in elk captured by net gun. Journal of wildlife diseases 20040701
Comparative immobilization of wild felids in Thailand. Journal of wildlife diseases 20040701
Effect of intratesticular injection of xylazine/ketamine combination on canine castration. Journal of veterinary science 20040601
Isoflurane sparing action of epidurally administered xylazine hydrochloride in anesthetized dogs. American journal of veterinary research 20040601
Anaesthesia with midazolam/medetomidine/fentanyl in chinchillas (Chinchilla lanigera) compared to anaesthesia with xylazine/ketamine and medetomidine/ketamine. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20040601
Effect of gamma-hydroxybutyric acid on tissue Na+,K- ATPase levels after experimental head trauma. Acta anaesthesiologica Scandinavica 20040501
Lack of efficacy of injectable ketamine with xylazine or diazepam for anesthesia in chickens. Lab animal 20040501
The effects of anesthesia on the clinical chemistry of New Zealand White rabbits. Contemporary topics in laboratory animal science 20040501
Comparison of the analgesic effects of xylazine in sheep via three different administration routes. Australian veterinary journal 20040501
An animal model for ultrasound lung imaging. Ultrasound in medicine & biology 20040501
The effect of tiletamine/zolazepam (Zoletile) combination with xylazine or medetomidine on electroencephalograms in dogs. The Journal of veterinary medical science 20040501
A blood-brain barrier disruption model eliminating the hemodynamic effect of ketamine. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20040501
Determination of xylazine and its metabolites by GC-MS in equine urine for doping analysis. Journal of pharmaceutical and biomedical analysis 20040401
A comparison of two intramuscular doses of xylazine-ketamine combination and tolazoline reversal in llamas. Veterinary anaesthesia and analgesia 20040401
The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. Veterinary anaesthesia and analgesia 20040401
Effects of xylazine on canine coronary artery vascular rings. American journal of veterinary research 20040401
Effects of glycopyrrolate on cardiorespiratory function in horses anesthetized with halothane and xylazine. American journal of veterinary research 20040401
Effects of a muscarinic type-2 antagonist on cardiorespiratory function and intestinal transit in horses anesthetized with halothane and xylazine. American journal of veterinary research 20040401
Influence of morphine sulfate on the halothane sparing effect of xylazine hydrochloride in horses. American journal of veterinary research 20040401
Immobilization of mule deer with thiafentanil (A-3080) or thiafentanil plus xylazine. Journal of wildlife diseases 20040401
New technique for measurement of left ventricular pressure in conscious mice. American journal of physiology. Heart and circulatory physiology 20040301
Ketaset-Rompun extends the effective interstimulus interval in long-trace taste-aversion conditioning in rats. Behavioural processes 20040227
Canine electroencephalographic recording technique: findings in normal and epileptic dogs. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20040201
Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET. Nuclear medicine and biology 20040201
Comparison of the depressive effects of four anesthetic regimens on ventilatory and cardiovascular variables in the guinea pig. Comparative medicine 20040201
C-fos expression in rat brain nuclei following incisor tooth movement. Journal of dental research 20040101
Effect of caudal epidural xylazine on intraoperative distress and post-operative pain in Holstein heifers. Veterinary anaesthesia and analgesia 20040101
Cardiopulmonary effects of combined xylazine-guaiphenesin-ketamine infusion and extradural (inter-coccygeal lidocaine) anaesthesia in calves. Veterinary anaesthesia and analgesia 20040101
Isoflurane with morphine is a suitable anaesthetic regimen for embryo transfer in the production of transgenic rats. Laboratory animals 20040101
Does preoperative administration of metamizol (Novalgin) affect postoperative body weight and duration of recovery from ketamine-xylazine anaesthesia in mice undergoing embryo transfer: a preliminary report. Laboratory animals 20040101
Exposure to warmer postoperative temperatures reduces hypothermia caused by anaesthesia and significantly increases the implantation rate of transferred embryos in the mouse. Laboratory animals 20040101
Elevation of blood glucose following anaesthetic treatment in C57BL/6 mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040101
A comparison of xylazine and medetomidine in an anesthetic combination in New Zealand White Rabbits. Contemporary topics in laboratory animal science 20040101
Two reentrant pathways in the hippocampal-entorhinal system. Hippocampus 20040101
Electrophysiological responses to imidazoline/alpha2-receptor agonists in rabbit sinoatrial node pacemaker cells. Acta pharmacologica Sinica 20031201
[Injection anesthesia administered in the mid-anesthesia period after ether induction in laboratory rats]. Ceskoslovenska fysiologie 20031201
Cardiovascular effects of xylazine recorded with telemetry in the dog. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20031201
Temporal changes in ventricular function assessed echocardiographically in conscious and anesthetized mice. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20031101
Evaluation of different doses of propofol in xylazine pre-medicated horses. Veterinary anaesthesia and analgesia 20031001
A comparison of carfentanil/xylazine and Telazol/xylazine for immobilization of white-tailed deer. Journal of wildlife diseases 20031001
Ketamine-xylazine-induced slow (< 1.5 Hz) oscillations in the rat piriform (olfactory) cortex are functionally correlated with respiration. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030903
Antagonistic effects of intravenous or epidural atipamezole on xylazine-induced dorsolumbar epidural analgesia in cattle. Veterinary journal (London, England : 1997) 20030901
The effect of anesthesia on the pharmacokinetics of sublingually administered verapamil in rabbits. Journal of pharmaceutical sciences 20030901
Drug abuse with inhalated xylazine. European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20030901
Synthesis of 3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazoles, displaying combined 5-HT uptake inhibiting and alpha(2)-adrenoceptor antagonistic activities: a novel series of potential antidepressants. Bioorganic & medicinal chemistry letters 20030818
Simultaneous determination of ketamine and xylazine in canine plasma by liquid chromatography with ultraviolet absorbance detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705
Effects of ketamine/xylazine on expression of tumor necrosis factor-alpha, inducible nitric oxide synthase, and cyclo-oxygenase-2 in rat gastric mucosa during endotoxemia. Shock (Augusta, Ga.) 20030701
The sedative and behavioral effects of nalbuphine in dogs. Contemporary topics in laboratory animal science 20030701
Clinical observations during induction and recovery of xylazine-midazolam- propofol anesthesia in horses. The Journal of veterinary medical science 20030701
A comparison of the antinociceptive effects of xylazine, detomidine and romifidine on experimental pain in horses. Veterinary anaesthesia and analgesia 20030701
Anesthesia of polar bears using xylazine-zolazepam-tiletamine or zolazepam-tiletamine. Journal of wildlife diseases 20030701
Evaluation of three combinations of anesthetics for use in free-ranging alpine marmots (Marmota marmota). Journal of wildlife diseases 20030701
Immobilization of North American porcupines (Erethizon dorsatum) using ketamine and xylazine. Journal of wildlife diseases 20030701
Dose-threshold for thyroid tumor-promoting effects of xylazine in rats. Toxicology 20030630
A reported case involving impaired driving following self-administration of xylazine. Forensic science international 20030624
Interference of anaesthetics with radioligand binding in neuroreceptor studies. European journal of nuclear medicine and molecular imaging 20030601
Interactions of xylazine and detomidine with alpha2-adrenoceptors in brain tissue from cattle, swine and rats. Journal of veterinary pharmacology and therapeutics 20030601
[Standing behavior in horses after inhalation anesthesia with isoflurane (Isoflo) and postanesthetic sedation with romifidine (Sedivet) or xylazine (Rompun)]. DTW. Deutsche tierarztliche Wochenschrift 20030601
Ketamine/xylazine attenuates LPS-induced iNOS expression in various rat tissues. The Journal of surgical research 20030601
Effect of epidural fat on xylazine-induced dorsolumbar epidural analgesia in cattle. Veterinary journal (London, England : 1997) 20030501
Effect of ketoprofen, lidocaine local anesthesia, and combined xylazine and lidocaine caudal epidural anesthesia during castration of beef cattle on stress responses, immunity, growth, and behavior. Journal of animal science 20030501
Age and anesthetic effects on murine electrocardiography. Life sciences 20030411
Responsiveness to noradrenaline in aorta from wild-type, nitric oxide synthase-2, nitric oxide synthase-3 and alpha2A/D-adrenoceptor knockout mice. European journal of pharmacology 20030411
Effects of the anaesthetic/tranquillizer treatments on selected plasma biochemical parameters in NZW rabbits. Laboratory animals 20030401
Xylazine does not induce retrograde flow of spermatozoa into the urinary bladder of sexually rested boars. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20030401
The cardiopulmonary effects of severe blood loss in anesthetized horses. Veterinary anaesthesia and analgesia 20030401
Effects of alpha-2 adrenoceptor agonists during recovery from isoflurane anaesthesia in horses. Equine veterinary journal 20030301
Effects of atropine, scopolamine and xylazine on the placement of an orally administered magnet in cows. The Veterinary record 20030301
Tissue distribution of xylazine in a suicide by hanging. Journal of analytical toxicology 20030301
The significance of intrathecal catheter location in rats. Anesthesia and analgesia 20030201
Effect of aerosolized albuterol sulfate on resting energy expenditure determined by use of open-flow indirect calorimetry in horses with recurrent airway obstruction. American journal of veterinary research 20030201
Japanese Society for Animal Reproduction: award for outstanding research 2002. The development and prevalence of the transfer technique for frozen-thawed embryos of Japanese black beef cattle in Tochigi Prefecture. The Journal of reproduction and development 20030201
The effect of ketamine/xylazine anesthesia on sensory and motor evoked potentials in the rat. Spinal cord 20030101
Evaluation of transcutaneous Doppler ultrasonography for the measurement of blood flow in the femoral artery of pigs. American journal of veterinary research 20030101
Analgesic and systemic effects of ketamine, xylazine, and lidocaine after subarachnoid administration in goats. American journal of veterinary research 20030101
Xylazine, an alpha 2-adrenergic agonist, induces apoptosis of rat thymocytes and a thymocyte hybridoma line in vitro. Methods and findings in experimental and clinical pharmacology 20030101
Effect of ovariohysterectomy on canine postsurgical leukocyte function. Acta veterinaria Hungarica 20030101
Chemical restraint of peccaries with tiletamine/zolazepam and xylazine or tiletamine/zolazepam and butorphanol. Veterinary anaesthesia and analgesia 20030101
Pharmacokinetics of xylazine, 2,6-dimethylaniline, and tolazoline in tissues from yearling cattle and milk from mature dairy cows after sedation with xylazine hydrochloride and reversal with tolazoline hydrochloride. Veterinary therapeutics : research in applied veterinary medicine 20030101
Preliminary study of the effects of xylazine or detomidine with or without butorphanol for standing sedation in dairy cattle. Veterinary therapeutics : research in applied veterinary medicine 20030101
Similar half-octave TTS protection of the cochlea by xylazine/ketamine or sympathectomy. Hearing research 20021201
Male and female rats express similar blood pressure responses to 'push-pull' gravitational stress. Journal of applied physiology (Bethesda, Md. : 1985) 20021201
Cardiopulmonary effects of xylazine and acepromazine in pregnant cows in late gestation. American journal of veterinary research 20021201
In vitro effects of oxytocin, acepromazine, detomidine, xylazine, butorphanol, terbutaline, isoproterenol, and dantrolene on smooth and skeletal muscles of the equine esophagus. American journal of veterinary research 20021201
Effects of treatment with oxytocin, xylazine butorphanol, guaifenesin, acepromazine, and detomidine on esophageal manometric pressure in conscious horses. American journal of veterinary research 20021201
Tiletamine-zolazepam, ketamine, and xylazine anesthesia of captive cheetah (Acinonyx jubatus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20021201
Surgical implantation of radio transmitters in arctic foxes (Alopex lagopus) on Svalbard, Norway. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20021201
Changes in hepatic and renal enzyme concentrations and heart and respiratory rates in new zealand white rabbits after anesthetic treatments. Contemporary topics in laboratory animal science 20021101
Clinical comparison of xylazine and medetomidine for premedication of horses. Journal of the American Veterinary Medical Association 20021015
Xylazine-induced attenuation of dorsal displacement of the soft palate associated with epiglottic dysfunction in a horse. Journal of the American Veterinary Medical Association 20020801
Evaluation of anesthesia effects in a rat animal model using otoacoustic emission protocols. Hearing research 20020801
Ultrasonographic evaluation of reticular motility in cows after administration of atropine, scopolamine and xylazine. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20020801
Cardiovascular phenotypes of kinin B2 receptor- and tissue kallikrein-deficient mice. Hypertension (Dallas, Tex. : 1979) 20020701
Investigation of neurotransmission in vas deferens from alpha(2A/D)-adrenoceptor knockout mice. British journal of pharmacology 20020701
Effect of general anesthesia and minor surgical trauma on urine and serum measurements in horses. American journal of veterinary research 20020701
The effects of xylazine, detomidine, acepromazine and butorphanol on equine solid phase gastric emptying rate. Equine veterinary journal 20020701
Impact of anesthesia on cardiac function during echocardiography in mice. American journal of physiology. Heart and circulatory physiology 20020601
Effects of ketamine-xylazine and isoflurane on insulin sensitivity in dehydroepiandrosterone sulfate-treated minipigs (Sus scrofa domestica). Comparative medicine 20020601
Use of the anesthetic combination of tiletamine, zolazepam, ketamine, and xylazine for neutering feral cats. Journal of the American Veterinary Medical Association 20020515
Anesthesia affects the disposition of [18F]fluoro-A-85380: a PET study in monkeys. Synapse (New York, N.Y.) 20020401
Effects of propofol as an anaesthetic agent in adult lions (Panthera leo): a comparison with two established protocols. Research in veterinary science 20020401
Early effects of tribromoethanol, ketamine/xylazine, pentobarbitol, and isoflurane anesthesia on hepatic and lymphoid tissue in ICR mice. Comparative medicine 20020201
Neurohormonal and metabolic effects of medetomidine compared with xylazine in beagle dogs. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20020101
Semen collection from mice: electroejaculation. Reproduction, fertility, and development 20020101
The functional alpha-adrenoceptor in dog caudal vesical arteries is mainly an alpha1A subtype. Autonomic & autacoid pharmacology 20020101
Oral imipramine and intravenous xylazine for pharmacologically-induced ex copula ejaculation in stallions. Animal reproduction science 20011203
Severe intoxication from xylazine inhalation. Pediatric emergency care 20011201
Effects of avertin versus xylazine-ketamine anesthesia on cardiac function in normal mice. American journal of physiology. Heart and circulatory physiology 20011101
Treatment of hypoxemia during xylazine-tiletamine-zolazepam immobilization of wapiti. The Canadian veterinary journal = La revue veterinaire canadienne 20011101
Focal synchronization of ripples (80-200 Hz) in neocortex and their neuronal correlates. Journal of neurophysiology 20011001
Differences in normal values for murine white blood cell counts and other hematological parameters based on sampling site. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20011001
Optimization of intraperitoneal injection anesthesia in mice: drugs, dosages, adverse effects, and anesthesia depth. Comparative medicine 20011001
Anesthesia protocol for hyperpnea-induced airway obstruction in the guinea pig. Comparative medicine 20011001
The effects of ketamine-xylazine anesthesia on cerebral blood flow and oxygenation observed using nuclear magnetic resonance perfusion imaging and electron paramagnetic resonance oximetry. Brain research 20010921
Existence of alpha(1A)- and alpha(1B)-adrenoceptor subtypes in canine mandibular alveolar arteries. Clinical and experimental pharmacology & physiology 20010901
Effects of dexamethasone on emesis in cats sedated with xylazine hydrochloride. American journal of veterinary research 20010801
Effects of anesthesia on cystometry and leak point pressure of the female rat. Life sciences 20010727
Prejunctional actions of methylenedioxymethamphetamine in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice. European journal of pharmacology 20010706
Activation of alpha(2)-receptors in the rostral ventrolateral medulla evokes natriuresis by a renal nerve mechanism. American journal of physiology. Regulatory, integrative and comparative physiology 20010701
A novel anaesthetic regimen for surgical procedures in guineapigs. Laboratory animals 20010701
A xylazine infusion regimen to provide analgesia in sheep. Laboratory animals 20010701
Plasma glucocorticoid concentrations after fentanyl-droperidol, ketamine-xylazine and ketamine-diazepam anaesthesia in New Zealand white rabbits. The Veterinary record 20010623
Vascular actions of MDMA involve alpha1 and alpha2-adrenoceptors in the anaesthetized rat. British journal of pharmacology 20010601
[Anesthesia of the New Zealand rabbit using the the combination of tiletamine-zolazepam and ketamine-midazolam with or without xylazine]. The Canadian veterinary journal = La revue veterinaire canadienne 20010601
Non-invasive echocardiographic studies in mice: influence of anesthetic regimen. Life sciences 20010601
The reversal of xylazine hydrochloride by yohimbine and 4-aminopyridine in goats. Journal of the South African Veterinary Association 20010601
Interaction of formamidine pesticides with the presynaptic alpha(2)-adrenoceptor regulating. Toxicology and applied pharmacology 20010501
An ethicist's commentary on animal welfare versus food safety in collecting antler velvet. The Canadian veterinary journal = La revue veterinaire canadienne 20010501
Anesthesia. Current protocols in immunology 20010501
Relationship between EEG potentials and intracellular activity of striatal and cortico-striatal neurons: an in vivo study under different anesthetics. Cerebral cortex (New York, N.Y. : 1991) 20010401
Promoting effects of xylazine on development of thyroid tumors in rats initiated with N-bis(2-hydroxypropyl)nitrosamine and the mechanism of action. Carcinogenesis 20010401
Capture and immobilization of wild brown palm civets in Western Ghats. Journal of wildlife diseases 20010401
Comparisons of the effects of anesthesia and stress on release of tumor necrosis factor-alpha, leptin, and nitric oxide in adult male rats. Experimental biology and medicine (Maywood, N.J.) 20010401
Combined xylazine and ketamine as an analgesic regimen in sheep. Australian veterinary journal 20010301
Use of naloxone to reverse carfentanil citrate-induced hypoxemia and cardiopulmonary depression in Rocky Mountain wapiti (Cervus elaphus nelsoni). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20010301
Immunomodulatory effect of xylazine, an alpha(2) adrenergic agonist, on rat spleen cells in culture. Journal of neuroimmunology 20010201
The anti-nociceptive efficacy of low dose intramuscular xylazine in lambs. Research in veterinary science 20010201
Results of cystometry and urethral pressure profilometry in dogs sedated with medetomidine or xylazine. American journal of veterinary research 20010201
The effect of hepatic microsomal cytochrome P450 monooxygenases on monensin-sulfadimidine interactions in broilers. Journal of veterinary pharmacology and therapeutics 20010201
Comparison of extradural injections of lignocaine and xylazine in azaperone-sedated pigs. Veterinary journal (London, England : 1997) 20010101
Hypotensive infarction of the spinal cord in a rhesus macaque (Macaca mulatta). Veterinary pathology 20010101
Cardiovascular and haemodynamic effects of intramuscular doses of xylazine in conscious sheep. Australian veterinary journal 20010101
Severe intoxication with the veterinary tranquilizer xylazine in humans. Journal of analytical toxicology 20010101
Corneal toxicity of xylazine and clonidine, in combination with ketamine, in the rat. Ophthalmic research 20010101
Urethane suppresses rat lung inducible cyclooxygenase and nitric oxide synthase mRNA levels. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20001201
New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central alpha 2-antagonistic activity as potential antidepressants. Bioorganic & medicinal chemistry letters 20000103
Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits. Laboratory animal science 19990401
Effects of aging on prejunctional control of neurotransmission in the rat. Annals of the New York Academy of Sciences 19960615
Emesis induced in domestic pigs: a new experimental tool for detection of antiemetic drugs and for evaluation of emetogenic potential of new anticancer agents. Journal of pharmacological and toxicological methods 19941001
Pro and anticonvulsant effects of xylazine on convulsion models in rodents. Veterinary and human toxicology 19940201
Alterations in epinephrine-induced arrhythmogenesis after xylazine and subsequent yohimbine administration in isoflurane-anesthetized dogs. American journal of veterinary research 19880701
Effects of enalapril on changes in cardiac output and organ vascular resistances induced by alpha 1- and alpha 2-adrenoceptor agonists in pithed normotensive rats. British journal of pharmacology 19880601
Effects of xylazine and ketamine on epinephrine-induced arrhythmia in the dog. Veterinary surgery : VS 19870101
Xylazine-ketamine-induced anesthesia in rats and its antagonism by yohimbine. Journal of the American Veterinary Medical Association 19861101
Alteration in the arrhythmogenic dose of epinephrine (ADE) following xylazine administration to halothane-anesthetized dogs. Journal of veterinary pharmacology and therapeutics 19860601
Influence of nifedipine on xylazine-induced acute pressor response in halothane-anesthetized dogs. American journal of veterinary research 19850901
Effects of butorphanol, flunixin, levorphanol, morphine, and xylazine in ponies. American journal of veterinary research 19840201
Effects of xylazine and acetylpromazine upon induced ventricular fibrillation in dogs anesthetized with thiamylal and halothane. American journal of veterinary research 19750901
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