Home Other Building Blocks 1,7-Phenanthroline

1,7-Phenanthroline

CAS No.:
230-46-6
Catalog Number:
AG002LTP
Molecular Formula:
C12H8N2
Molecular Weight:
180.2053
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Product Description
Catalog Number:
AG002LTP
Chemical Name:
1,7-Phenanthroline
CAS Number:
230-46-6
Molecular Formula:
C12H8N2
Molecular Weight:
180.2053
MDL Number:
MFCD00004971
IUPAC Name:
1,7-phenanthroline
InChI:
InChI=1S/C12H8N2/c1-3-9-5-6-11-10(4-2-7-13-11)12(9)14-8-1/h1-8H
InChI Key:
OZKOMUDCMCEDTM-UHFFFAOYSA-N
SMILES:
c1cnc2c(c1)ccc1c2cccn1
NSC Number:
35679
Properties
Complexity:
205  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
180.069g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
180.21g/mol
Monoisotopic Mass:
180.069g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
25.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.5  
Literature
Title Journal
Aqua-chlorido(3,5-dinitro-2-oxidobenzo-ato-κ(2)O(1),O(2))(1,10-phenanthroline-κ(2)N,N')chromium(III). Acta crystallographica. Section E, Structure reports online 20120401
The chain structure of [Ni(C(4)H(2)O(4))(C(12)H(8)N(2))(H(2)O)](n) with different types of fumarate bridging. Acta crystallographica. Section E, Structure reports online 20120201
(5-Amino-isophthalato-κN)triaqua-(1,10-phenanthroline-κN,N')nickel(II) trihydrate. Acta crystallographica. Section E, Structure reports online 20110401
The effects of PAHs and N-PAHs on retinoid signaling and Oct-4 expression in vitro. Toxicology letters 20110205
The chromatin remodelling complex B-WICH changes the chromatin structure and recruits histone acetyl-transferases to active rRNA genes. PloS one 20110101
Changes in interleukin-1 signal modulators induced by 3,4-methylenedioxymethamphetamine (MDMA): regulation by CB2 receptors and implications for neurotoxicity. Journal of neuroinflammation 20110101
Use of specific chemical reagents for detection of modified nucleotides in RNA. Journal of nucleic acids 20110101
Increased interleukin-1β levels following low dose MDMA induces tolerance against the 5-HT neurotoxicity produced by challenge MDMA. Journal of neuroinflammation 20110101
Bis(propane-1,2-diammonium) benzene-1,2,4,5-tetra-carboxyl-ate dihydrate. Acta crystallographica. Section E, Structure reports online 20101201
Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63. PLoS pathogens 20101001
Partial biochemical characterization of a metalloproteinase from the bloodstream forms of Trypanosoma brucei brucei parasites. The protein journal 20100501
(Benzoato-κO)bis-(1,10-phenanthroline-κN,N')copper(II) chloride benzoic acid disolvate. Acta crystallographica. Section E, Structure reports online 20100501
3-Carboxy-pyrazino[2,3-f][1,10]phenanthrolin-9-ium-2-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20100401
Bis(1,10-phenanthroline-κN,N')(sulfato-κO,O')cobalt(II) propane-1,3-diol solvate. Acta crystallographica. Section E, Structure reports online 20100301
Effects of tert-butylhydroquinone on intestinal inflammatory response and apoptosis following traumatic brain injury in mice. Mediators of inflammation 20100101
Chloridobis(1,10-phenanthroline-κN,N')(2,2,2-trichloro-acetato-κO)cobalt(II). Acta crystallographica. Section E, Structure reports online 20100101
(Carbonato-κO,O')bis-(1,10-phenan-throline-κN,N')cobalt(III) nitrate monohydrate. Acta crystallographica. Section E, Structure reports online 20100101
Elastase secretion in Acanthamoeba polyphaga. Acta tropica 20091101
Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper(II) complex with N-(9H-purin-6-yl)benzenesulfonamide and 1,10-phenantroline. Antitumor activity in human Caco-2 cells and Jurkat T lymphocytes. Evaluation of p53 and Bcl-2 proteins in the apoptotic mechanism. Journal of inorganic biochemistry 20090601
Synthesis, characterization, and biological activity studies of copper(II) mixed compound with histamine and nalidixic acid. Bioinorganic chemistry and applications 20090101
Intraspecies differences in hemostatic venom activities of the South American rattlesnakes, Crotalus durissus cumanensis, as revealed by a range of protease inhibitors. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080901
μ-Aqua-κO:O-di-μ-4-methyl-benzoato-κO:O'-bis-[(4-methyl-benzoato-κO)(1,10-phenanthroline-κN,N')nickel(II)]. Acta crystallographica. Section E, Structure reports online 20080701
Bis(piperazinediium) benzene-1,2,4,5-tetra-carboxyl-ate hexa-hydrate. Acta crystallographica. Section E, Structure reports online 20080401
Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. PLoS medicine 20080301
Expression of hepatic UDP-glucuronosyltransferase 1A1 and 1A6 correlated with increased expression of the nuclear constitutive androstane receptor and peroxisome proliferator-activated receptor alpha in male rats fed a high-fat and high-sucrose diet. Drug metabolism and disposition: the biological fate of chemicals 20080201
Exposure to ultrafine carbon particles at levels below detectable pulmonary inflammation affects cardiovascular performance in spontaneously hypertensive rats. Particle and fibre toxicology 20080101
Novel antipathogenic strategies against adherent enterobacterial strains isolated from the hospital environment. Roumanian archives of microbiology and immunology 20080101
(1,10-Phenanthroline-κN,N')bis-(2,2,6,6-tetra-methyl-heptane-3,5-dionato-κO,O')nickel(II). Acta crystallographica. Section E, Structure reports online 20080101
Phenantroline, lovastatin, and mebendazole do not inhibit oviposition in the murine experimental infection with Angiostrongylus costaricensis. Parasitology research 20070101
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Toxic effects and oxidative stress in higher plants exposed to polycyclic aromatic hydrocarbons and their N-heterocyclic derivatives. Environmental toxicology and chemistry 20061201
Contribution to the chemistry of the Belousov-Zhabotinsky reaction. Products of the Ferriin-Bromomalonic acid and the Ferriin-Malonic acid reactions. The journal of physical chemistry. A 20061130
Platelet aggregation-induced by caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate. The Journal of pharmacology and experimental therapeutics 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Cu2+ (1,10 phenanthroline)3 is an open-channel blocker of the human skeletal muscle sodium channel. British journal of pharmacology 20060401
Pharmacokinetic and in vivo evaluation of a self-assembled gadolinium(III)-iron(II) contrast agent with high relaxivity. Contrast media & molecular imaging 20060101
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Cu(II) complexes with a sulfonamide derived from benzoguanamine. Oxidative cleavage of DNA in the presence of H2O2 and ascorbate. Journal of inorganic biochemistry 20050701
Induction of colonic transmural inflammation by Bacteroides fragilis: implication of matrix metalloproteinases. Inflammatory bowel diseases 20050201
In vivo mutagenicity of benzo[f]quinoline, benzo[h]quinoline, and 1,7-phenanthroline using the lacZ transgenic mice. Mutation research 20040411
Endogenous angiotensin II in the regulation of hypoxic pulmonary vasoconstriction in anaesthetized dogs. Critical care (London, England) 20040101
1,10-Phenanthroline phosphorylates (activates) MAP kinase in Xenopus oocytes. Cellular signalling 20031201
A rational study of crystal engineering of supramolecular assemblies of 1,2,4,5-benzenetetracarboxylic acid. The Journal of organic chemistry 20031128
Regulated cell surface pro-EGF ectodomain shedding is a zinc metalloprotease-dependent process. The Journal of biological chemistry 20031114
Purification and properties of an arginyl aminopeptidase from Debaryomyces hansenii. International journal of food microbiology 20030901
Induction of hepatic phase II drug-metabolizing enzymes by 1,7-phenanthroline in rats is accompanied by induction of MRP3. Drug metabolism and disposition: the biological fate of chemicals 20030601
Reaction of alpha-oxoketene-N,S-arylaminoacetals with Vilsmeier reagents: an efficient route to highly functionalized quinolines and their benzo/hetero-fused analogues. The Journal of organic chemistry 20030516
Activation of the human Ah receptor by aza-polycyclic aromatic hydrocarbons and their halogenated derivatives. Biological & pharmaceutical bulletin 20030401
Enzymes with gelatinolytic activity can be found in Tityus bahiensis and Tityus serrulatus venoms. Toxicon : official journal of the International Society on Toxinology 20020701
Therapeutic effect of phenantroline in two rat models of inflammatory bowel disease. Scandinavian journal of gastroenterology 20011201
Intracellular iron, but not copper, plays a critical role in hydrogen peroxide-induced DNA damage. Free radical biology & medicine 20010815
Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells. The Biochemical journal 19960115
Chelatable metal ions are not required for aryl hydrocarbon receptor transformation to a DNA binding form: phenanthrolines are possible competitive antagonists of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Archives of biochemistry and biophysics 19920815
The binding of transformed aromatic hydrocarbon (Ah) receptor to its DNA recognition site is not affected by metal depletion. Molecular and cellular endocrinology 19900212
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