Expression of CYP4V2 in human THP1 macrophages and its transcriptional regulation by peroxisome proliferator-activated receptor gamma.

Toxicology and applied pharmacology 20170901

Mono-2-ethylhexyl phthalate inhibits human extravillous trophoblast invasion via the PPARγ pathway.

Toxicology and applied pharmacology 20170715

6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ.

Oncotarget 20170627

CYP4F2 repression and a modified alpha-tocopherol (vitamin E) metabolism are two independent consequences of ethanol toxicity in human hepatocytes.

Toxicology in vitro : an international journal published in association with BIBRA 20170401

Bisphenol A and its derivatives tetrabromobisphenol A and tetrachlorobisphenol A induce apelin expression and secretion in ovarian cancer cells through a peroxisome proliferator-activated receptor gamma-dependent mechanism.

Toxicology letters 20170305

Di-(2-ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPARγ.

Toxicology and applied pharmacology 20170201

Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma.

Frontiers in pharmacology 20170101

PPAR-γ activation attenuates deltamethrin-induced apoptosis by regulating cytosolic PINK1 and inhibiting mitochondrial dysfunction.

Toxicology letters 20161017

Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro.

Environmental science & technology 20161004

Bisphenol S- and bisphenol A-induced adipogenesis of murine preadipocytes occurs through direct peroxisome proliferator-activated receptor gamma activation.

International journal of obesity (2005) 20161001

Chrysin, a PPAR-γ agonist improves myocardial injury in diabetic rats through inhibiting AGE-RAGE mediated oxidative stress and inflammation.

Chemico-biological interactions 20160425

Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway.

Oncotarget 20160301

Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis.

Scientific reports 20160101

Endogenous 2-Arachidonoylglycerol Alleviates Cyclooxygenases-2 Elevation-Mediated Neuronal Injury From SO2 Inhalation via PPARγ Pathway.

Toxicological sciences : an official journal of the Society of Toxicology 20151001

Peroxisome proliferator-activated receptor γ controls ingestive behavior, agouti-related protein, and neuropeptide Y mRNA in the arcuate hypothalamus.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20150318

Involvement of PPARγ in emodin-induced HK-2 cell apoptosis.

Toxicology in vitro : an international journal published in association with BIBRA 20150201

Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.

International journal of molecular sciences 20150101

Protective Effect of Notoginsenoside R1 on an APP/PS1 Mouse Model of Alzheimer's Disease by Up-Regulating Insulin Degrading Enzyme and Inhibiting Aβ Accumulation.

CNS & neurological disorders drug targets 20150101

Rosiglitzone suppresses angiotensin II-induced production of KLF5 and cell proliferation in rat vascular smooth muscle cells.

PloS one 20150101

Hesperidin blunts streptozotocin-isoproternol induced myocardial toxicity in rats by altering of PPAR-γ receptor.

Chemico-biological interactions 20140805

Rosiglitazone inhibits chlorpyrifos-induced apoptosis via modulation of the oxidative stress and inflammatory response in SH-SY5Y cells.

Toxicology and applied pharmacology 20140715

Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma.

Antioxidants & redox signaling 20140520

Long term intake of 0.1% ethanol decreases serum adiponectin by suppressing PPARγ expression via p38 MAPK pathway.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140301

Hydroxysafflor yellow A of Carthamus tinctorius attenuates lung injury of aged rats exposed to gasoline engine exhaust by down-regulating platelet activation.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20140215

Chrysin and luteolin alleviate vascular complications associated with insulin resistance mainly through PPAR-γ activation.

The American journal of Chinese medicine 20140101

Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling.

Reproductive toxicology (Elmsford, N.Y.) 20131201

Antifibrotic effect of atorvastatin on paraquat-induced pulmonary fibrosis: role of PPARγ receptors.

European journal of pharmacology 20131115

Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib.

Journal of lipid research 20131101

A novel natural Nrf2 activator with PPARγ-agonist (monascin) attenuates the toxicity of methylglyoxal and hyperglycemia.

Toxicology and applied pharmacology 20131101

Perfluorooctane sulfonate induces neuronal and oligodendrocytic differentiation in neural stem cells and alters the expression of PPARγ in vitro and in vivo.

Toxicology and applied pharmacology 20130515

Resveratrol mediates anti-atherogenic effects on cholesterol flux in human macrophages and endothelium via PPARγ and adenosine.

European journal of pharmacology 20130105

Effects of parabens on adipocyte differentiation.

Toxicological sciences : an official journal of the Society of Toxicology 20130101

COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells.

Molecular cancer therapeutics 20130101

Induction of the fatty acid 2-hydroxylase (FA2H) gene by Δ(9)-tetrahydrocannabinol in human breast cancer cells.

The Journal of toxicological sciences 20130101

Sodium dodecyl sulfate and sodium dodecyl benzenesulfonate are ligands for peroxisome proliferator-activated receptor γ.

The Journal of toxicological sciences 20130101

Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.

The Journal of biological chemistry 20121102

Activation of AMPK-Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects.

European journal of pharmacology 20121005

Nanoparticle-mediated delivery of pioglitazone enhances therapeutic neovascularization in a murine model of hindlimb ischemia.

Arteriosclerosis, thrombosis, and vascular biology 20121001

Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening.

The Journal of biological chemistry 20120921

Activation of PPARγ by restores mast cell numbers and reactivity in alloxan-diabetic rats by reducing the systemic glucocorticoid levels.

European journal of pharmacology 20120915

15-Deoxy-Δ¹²,¹⁴-prostaglandin J₂-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor γ ligand, modulates nuclear factor of activated T cells.

The Journal of pharmacology and experimental therapeutics 20120901

A peroxisome proliferator-activated receptor ligand MCC-555 imparts anti-proliferative response in pancreatic cancer cells by PPARgamma-independent up-regulation of KLF4.

Toxicology and applied pharmacology 20120901

Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells.

Investigative ophthalmology & visual science 20120831

Activation of adipogenesis by lipocalin-type prostaglandin D synthase-generated Δ¹²-PGJ₂ acting through PPARγ-dependent and independent pathways.

Gene 20120815

The endocrine disruptor diethylstilbestrol induces adipocyte differentiation and promotes obesity in mice.

Toxicology and applied pharmacology 20120815

Possible involvement of PPAR-gamma receptor and nitric oxide pathway in the anticonvulsant effect of acute pioglitazone on pentylenetetrazole-induced seizures in mice.

Epilepsy research 20120801

15-Deoxy-Δ(12,14)-prostaglandin J(2) attenuates the biological activities of monocyte/macrophage cell lines.

European journal of cell biology 20120801

Different roles of PPAR-γ activity on physiological and pathological alteration after myocardial ischemia.

Journal of cardiovascular pharmacology 20120801

Estrogen improves vascular function via peroxisome-proliferator-activated-receptor-γ.

Journal of molecular and cellular cardiology 20120801

Pioglitazone, a PPAR-γ activator, attenuates the severity of cerulein-induced acute pancreatitis by modulating early growth response-1 transcription factor.

Translational research : the journal of laboratory and clinical medicine 20120801

Cardioprotection from oxidative stress in the newborn heart by activation of PPARγ is mediated by catalase.

Free radical biology & medicine 20120715

Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor-γ in subtotal nephrectomized rat.

European journal of pharmacology 20120615

Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson's disease.

Experimental neurology 20120601

Hyperbaric oxygen preconditioning protects cortical neurons against oxygen-glucose deprivation injury: role of peroxisome proliferator-activated receptor-gamma.

Brain research 20120503

Monascus-fermented metabolite monascin suppresses inflammation via PPAR-γ regulation and JNK inactivation in THP-1 monocytes.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Peroxisome proliferator-activated receptor-γ activation with angiotensin II type 1 receptor blockade is pivotal for the prevention of blood-brain barrier impairment and cognitive decline in type 2 diabetic mice.

Hypertension (Dallas, Tex. : 1979) 20120501

Effects of bacterial and presystemic nitroreductase metabolism of 2-chloro-5-nitro-N-phenylbenzamide on its mutagenicity and bioavailability.

Chemico-biological interactions 20120415

PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney.

Biogerontology 20120401

Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma.

Acta neuropathologica 20120401

Eicosapentaenoic acid disrupts the balance between Tregs and IL-17+ T cells through PPARγ nuclear receptor activation and protects cardiac allografts.

The Journal of surgical research 20120301

Peroxisome proliferating activating receptor gamma-independent attenuation of interleukin 6 and interleukin 8 secretion from primary endometrial stromal cells by thiazolidinediones.

Fertility and sterility 20120301

Drug-targeted inhibition of peroxisome proliferator-activated receptor-gamma enhances the chemopreventive effect of anti-estrogen therapy.

Oncotarget 20120301

PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis.

The Journal of allergy and clinical immunology 20120201

Telmisartan exerts renoprotective actions via peroxisome proliferator-activated receptor-γ/hepatocyte growth factor pathway independent of angiotensin II type 1 receptor blockade.

Hypertension (Dallas, Tex. : 1979) 20120201

Angiogenic response of advanced glycation end products (AGEs) involves PPARgamma.

Indian journal of biochemistry & biophysics 20120201

Cell death is induced by ciglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) agonist, independently of PPARγ in human glioma cells.

Biochemical and biophysical research communications 20120106

Lycopene inhibits the proliferation of androgen-dependent human prostate tumor cells through activation of PPARγ-LXRα-ABCA1 pathway.

The Journal of nutritional biochemistry 20120101

Inhibition of lymphoma cell proliferation by peroxisomal proliferator-activated receptor-γ ligands via Wnt signaling pathway.

Cell biochemistry and biophysics 20120101

Synthesis and evaluation of 18F-labeled PPARγ antagonists.

Nuclear medicine and biology 20120101

Biochanin A ameliorates the cytokine secretion profile of lipopolysaccharide-stimulated macrophages by a PPARγ-dependent pathway.

Molecular medicine reports 20120101

The influence of peroxisome proliferator-activated receptor γ(1) during differentiation of mouse embryonic stem cells to neural cells.

Differentiation; research in biological diversity 20120101

Berberine ameliorates COX-2 expression in rat small intestinal mucosa partially through PPARγ pathway during acute endotoxemia.

International immunopharmacology 20120101

Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.

PloS one 20120101

Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease.

Journal of neuroinflammation 20120101

Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism.

PloS one 20120101

Mycophenolic acid induces ATP-binding cassette transporter A1 (ABCA1) expression through the PPARγ-LXRα-ABCA1 pathway.

Biochemical and biophysical research communications 20111104

Troglitazone-activated PPARγ inhibits LPS-induced lung alveolar type II epithelial cells injuries via TNF-α.

Molecular biology reports 20111101

Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism.

Journal of hepatology 20111101

Bezafibrate restores the inhibition of FSH-induced follicular development and steroidogenesis by tumor necrosis factor-alpha through peroxisome proliferator-activated receptor-gamma pathway in an in vitro mouse preantral follicle culture.

Biology of reproduction 20111101

Preventive action of curcumin in experimental acute pancreatitis in mouse.

The Indian journal of medical research 20111101

Antidepressant-like effect of pioglitazone in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway.

Behavioural brain research 20111031

Activation of Trim17 by PPARγ is involved in di(2-ethylhexyl) phthalate (DEHP)-induced apoptosis on Neuro-2a cells.

Toxicology letters 20111030

Early atheroma-derived agonists of peroxisome proliferator-activated receptor-γ trigger intramedial angiogenesis in a smooth muscle cell-dependent manner.

Circulation research 20111014

The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes.

The Journal of steroid biochemistry and molecular biology 20111001

Activation of peroxisome proliferators-activated receptor δ (PPARδ) promotes blastocyst hatching in mice.

Molecular human reproduction 20111001

Berberine hydrochloride attenuates cyclooxygenase-2 expression in rat small intestinal mucosa during acute endotoxemia.

Fitoterapia 20111001

Peroxisome proliferator-activated receptor γ (PPARγ) plays a critical role in the development of TGFβ resistance of H460 cell.

Cellular signalling 20111001

PPARgamma-independent increase in glucose uptake and adiponectin abundance in fat cells.

Endocrinology 20111001

Trans-10, cis-12 conjugated linoleic acid and the PPAR-γ agonist rosiglitazone attenuate lipopolysaccharide-induced TNF-α production by bovine immune cells.

Domestic animal endocrinology 20111001

[Effects of rosiglitazone on peroxisome proliferator activated receptor-γ pathway in patients with chronic obstructive pulmonary disease].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20111001

15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma.

Journal of cellular biochemistry 20110901

Relaxin causes selective outward remodeling of brain parenchymal arterioles via activation of peroxisome proliferator-activated receptor-γ.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110901

Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice.

American journal of physiology. Heart and circulatory physiology 20110901

Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway.

Biochemical pharmacology 20110901

Omega-3 fatty acids attenuate constitutive and insulin-induced CD36 expression through a suppression of PPAR α/γ activity in microvascular endothelial cells.

Thrombosis and haemostasis 20110901

Selenium levels affect the IL-4-induced expression of alternative activation markers in murine macrophages.

The Journal of nutrition 20110901

Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.

Nature medicine 20110828

Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ.

British journal of pharmacology 20110801

Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.

Environmental health perspectives 20110801

Rosiglitazone protects neuroblastoma cells against advanced glycation end products-induced injury.

Acta pharmacologica Sinica 20110801

Troglitazone induced apoptosis via PPARγ activated POX-induced ROS formation in HT29 cells.

Biomedical and environmental sciences : BES 20110801

Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells.

Circulation 20110712

Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated receptor-γ-dependent activity.

Biochemical and biophysical research communications 20110708

15-Deoxy-Δ12,14-prostaglandin J2 enhanced the anti-tumor activity of camptothecin against renal cell carcinoma independently of topoisomerase-II and PPARγ pathways.

Biochemical and biophysical research communications 20110708

Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells.

American journal of respiratory cell and molecular biology 20110701

Plasma rich in quercetin metabolites induces G2/M arrest by upregulating PPAR-γ expression in human A549 lung cancer cells.

Planta medica 20110701

Stable reporter cell lines for peroxisome proliferator-activated receptor γ (PPARγ)-mediated modulation of gene expression.

Analytical biochemistry 20110701

Peroxisome proliferator-activated receptor γ-induced T cell apoptosis reduces survival during polymicrobial sepsis.

American journal of respiratory and critical care medicine 20110701

Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.

Biochimica et biophysica acta 20110701

[Peroxisome proliferator activated receptor gamma activation and overexpression prevent hepatocellular apoptosis of nutritional fibrotic steatohepatitis in mice].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20110701

Troglitazone suppresses c-Myc levels in human prostate cancer cells via a PPARγ-independent mechanism.

Cancer biology & therapy 20110615

Rosiglitazone induces autophagy in H295R and cell cycle deregulation in SW13 adrenocortical cancer cells.

Experimental cell research 20110610

Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles.

The European respiratory journal 20110601

Double antioxidant activities of rosiglitazone against high glucose-induced oxidative stress in hepatocyte.

Toxicology in vitro : an international journal published in association with BIBRA 20110601

Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels.

Molecular pharmacology 20110601

Importance of inverse correlation between ALDH3A1 and PPARγ in tumor cells and tissue regeneration.

Chemico-biological interactions 20110530

Electrophilic fatty acids regulate matrix metalloproteinase activity and expression.

The Journal of biological chemistry 20110506

Rubus suavissimus S. Lee extract increases early adipogenesis in 3T3-L1 preadipocytes.

Journal of natural medicines 20110401

Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase.

Cardiovascular research 20110401

Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking.

Biological psychiatry 20110401

Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.

The Journal of clinical investigation 20110401

Peroxisome proliferator-activated receptor-gamma agonist induces regulatory T cells in a murine model of allergic rhinitis.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20110401

HO-1 Induced by Cilostazol Protects Against TNF-α-associated Cytotoxicity via a PPAR-γ-dependent Pathway in Human Endothelial Cells.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20110401

Role of different types of potassium channels and peroxisome proliferator-activated receptors γ in the antidepressant-like activity of bis selenide in the mouse tail suspension test.

Neuroscience letters 20110303

The short chain fatty acid sodium butyrate regulates the induction of CD1a in developing dendritic cells.

Immunobiology 20110301

Adenovirus-mediated peroxisome proliferator activated receptor gamma overexpression prevents nutritional fibrotic steatohepatitis in mice.

Scandinavian journal of gastroenterology 20110301

Peroxisome-proliferator-activated receptor γ mediates the second window of anaesthetic-induced preconditioning.

Experimental physiology 20110301

Phospholipidosis induced by PPARγ signaling in human bronchial epithelial (BEAS-2B) cells exposed to amiodarone.

Toxicological sciences : an official journal of the Society of Toxicology 20110301

IL-33 is expressed in human osteoblasts, but has no direct effect on bone remodeling.

Cytokine 20110301

[PPARγ up-regulates TGFβ/smad signal pathway repressor c-Ski].

Sheng li xue bao : [Acta physiologica Sinica] 20110225

Effect of Ganoderma lucidum extract on adipocyte differentiation and adiponectin gene expression in the murine pre-adipocyte cell line, 3T3-L1.

Phytotherapy research : PTR 20110201

Anti-proliferative effect of a putative endocannabinoid, 2-arachidonylglyceryl ether in prostate carcinoma cells.

Prostaglandins & other lipid mediators 20110201

Inhibitory effect of rosiglitazone on the acid-induced intracellular generation of hydrogen peroxide in cultured feline esophageal epithelial cells.

Naunyn-Schmiedeberg's archives of pharmacology 20110201

Combined treatment with the Cox-2 inhibitor niflumic acid and PPARγ ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells.

Cancer letters 20110128

[Effects of soluble epoxide hydrolase inhibitors on lipid metabolism and secretive functions of adipocytes].

Zhonghua yi xue za zhi 20110111

Role of PPARγ in the salutary effects of 17β-estradiol on Kupffer cell cytokine production following trauma-hemorrhage.

Journal of cellular physiology 20110101

Duration and magnitude of extracellular signal-regulated protein kinase phosphorylation determine adipogenesis or osteogenesis in human bone marrow-derived stem cells.

Yonsei medical journal 20110101

Activation of peroxisome-proliferator-activated receptors α and γ mediates remote ischemic preconditioning against myocardial infarction in vivo.

Experimental biology and medicine (Maywood, N.J.) 20110101

Inhibitory effects of rosiglitazone on lipopolysaccharide-induced inflammation in a murine model and HK-2 cells.

American journal of nephrology 20110101

Clofibrate relaxes the longitudinal smooth muscle of the mouse distal colon through calcium-mediated desensitisation of contractile machinery.

Pharmacology 20110101

Telmisartan prevents VCAM-1 induction and monocytic cell adhesion to endothelium exposed to non-uniform shear stress and TNF-α.

Clinical hemorheology and microcirculation 20110101

Atherogenic ω-6 Lipids Modulate PPAR- EGR-1 Crosstalk in Vascular Cells.

PPAR research 20110101

Novel Danshen methoxybenzo[b]furan derivative antagonizing adipogenic differentiation and production of inflammatory adipokines.

Chemico-biological interactions 20101205

hCG-induced down-regulation of PPARγ and liver X receptors promotes periovulatory progesterone synthesis by macaque granulosa cells.

Endocrinology 20101201

N,N-Bis-(8-hydroxyquinoline-5-yl methyl)-benzyl substituted amines (HQNBA): peroxisome proliferator-activated receptor (PPAR-γ) agonists with neuroprotective properties.

Bioorganic & medicinal chemistry letters 20101201

Regulation of liver fatty acid binding protein expression by clofibrate in hepatoma cells.

Biochemistry and cell biology = Biochimie et biologie cellulaire 20101201

Oleanolic acid reduces markers of differentiation in 3T3-L1 adipocytes.

Nutrition research (New York, N.Y.) 20101201

Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.

Glia 20101101

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Bioorganic & medicinal chemistry letters 20101101

PPAR activation has dichotomous control on the expression levels of cytosolic and secretory phospholipase A2 in astrocytes; inhibition in naïve, untreated cells and enhancement in LPS-stimulated cells.

Journal of neurochemistry 20101001

Telmisartan, a partial agonist of peroxisome proliferator-activated receptor gamma, improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia.

Brain research 20100924

Azelaic acid modulates the inflammatory response in normal human keratinocytes through PPARgamma activation.

Experimental dermatology 20100901

White tea extract induces apoptosis in non-small cell lung cancer cells: the role of peroxisome proliferator-activated receptor-{gamma} and 15-lipoxygenases.

Cancer prevention research (Philadelphia, Pa.) 20100901

Evidence of the involvement of K+ channels and PPARgamma receptors in the antidepressant-like activity of diphenyl diselenide in mice.

The Journal of pharmacy and pharmacology 20100901

Nifedipine activates PPARgamma and exerts antioxidative action through Cu/ZnSOD independent of blood-pressure lowering in SHRSP.

Journal of atherosclerosis and thrombosis 20100831

Rosiglitazone inhibits monocyte/macrophage adhesion through de novo adiponectin production in human monocytes.

Journal of cellular biochemistry 20100815

Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury.

Cardiovascular research 20100801

Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice.

Journal of hypertension 20100801

Role of PPAR gamma/nitric oxide synthase signaling in the cyclosporine-induced attenuation of endothelium-dependent renovascular vasodilation.

Journal of cardiovascular pharmacology 20100801

Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to peroxisome proliferator-activated receptor-gamma activation in mice with chronic cerebral hypoperfusion.

Stroke 20100801

Nifedipine inhibits advanced glycation end products (AGEs) and their receptor (RAGE) interaction-mediated proximal tubular cell injury via peroxisome proliferator-activated receptor-gamma activation.

Biochemical and biophysical research communications 20100723

8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK.

World journal of gastroenterology 20100721

Mycobacterium tuberculosis activates human macrophage peroxisome proliferator-activated receptor gamma linking mannose receptor recognition to regulation of immune responses.

Journal of immunology (Baltimore, Md. : 1950) 20100715

15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells.

Shock (Augusta, Ga.) 20100701

Peroxisome proliferator-activated receptor gamma activation inhibits progesterone-stimulated human MUC1 expression.

Molecular endocrinology (Baltimore, Md.) 20100701

Peroxisome proliferator-activated receptor gamma promotes neuroprotection by modulating cyclin D1 expression after focal cerebral ischemia.

Canadian journal of physiology and pharmacology 20100701

Thiazolidinediones inhibit TNF-alpha-mediated osteoclast differentiation of RAW264.7 macrophages and mouse bone marrow cells through downregulation of NFATc1.

Shock (Augusta, Ga.) 20100601

PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium.

Cardiovascular research 20100501

Thiazolidinediones as potent inducers of hepatocyte growth factor.

Hepatology (Baltimore, Md.) 20100501

Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation.

International journal of molecular medicine 20100501

Peroxisome proliferator-activated receptor-gamma (PPARgamma) modulates hypothalamic Trh regulation in vivo.

Molecular and cellular endocrinology 20100412

15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state.

Molecular pharmacology 20100401

Peroxisome proliferator-activated receptor gamma agonist rosiglitazone attenuates oxyhemoglobin-induced Toll-like receptor 4 expression in vascular smooth muscle cells.

Brain research 20100331

Selective effects of PPARgamma agonists and antagonists on human pre-adipocyte differentiation.

Diabetes, obesity & metabolism 20100301

The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells.

Molecular carcinogenesis 20100301

Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.

Journal of thrombosis and haemostasis : JTH 20100301

Relaxin signaling activates peroxisome proliferator-activated receptor gamma.

Molecular and cellular endocrinology 20100205

A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation.

Molecular pharmacology 20100201

Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema.

Neuropharmacology 20100201

Endothelium-dependent vasodilator effects of peroxisome proliferator-activated receptor beta agonists via the phosphatidyl-inositol-3 kinase-Akt pathway.

The Journal of pharmacology and experimental therapeutics 20100201

Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells.

Journal of neuroimmunology 20100125

A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120

12/15-Lipoxygenase inhibitor baicalein suppresses PPAR gamma expression and nuclear translocation induced by cerebral ischemia/reperfusion.

Brain research 20100111

The novel function of nesfatin-1: anti-hyperglycemia.

Biochemical and biophysical research communications 20100101

PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes.

Journal of Alzheimer's disease : JAD 20100101

Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia.

Brain research 20091211

Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells.

Atherosclerosis 20091201

Peroxisome proliferator-activated receptor gamma antagonists decrease Na+ transport via the epithelial Na+ channel.

Molecular pharmacology 20091201

Berberine improves free-fatty-acid-induced insulin resistance in L6 myotubes through inhibiting peroxisome proliferator-activated receptor gamma and fatty acid transferase expressions.

Metabolism: clinical and experimental 20091201

Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.

Physiological genomics 20091201

Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism.

Endocrinology 20091201

Eicosapentaenoic acid increases cytochrome P-450 2J2 gene expression and epoxyeicosatrienoic acid production via peroxisome proliferator-activated receptor γ in endothelial cells.

Journal of cardiology 20091201

Selective prostacyclin receptor agonism augments glucocorticoid-induced gene expression in human bronchial epithelial cells.

Journal of immunology (Baltimore, Md. : 1950) 20091115

Role of peroxisome proliferator-activated receptor beta/delta in chicken adipogenesis.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20091101

Peroxisome proliferator-activated receptor gamma activation alleviates postoperative ileus in mice by inhibition of Egr-1 expression and its downstream target genes.

The Journal of pharmacology and experimental therapeutics 20091101

The PPAR-gamma agonist rosiglitazone facilitates Akt rephosphorylation and inhibits apoptosis in cardiomyocytes during hypoxia/reoxygenation.

Diabetes, obesity & metabolism 20091101

Activation of peroxisome proliferator-activated receptor-gamma induces apoptosis on acute promyelocytic leukemia cells via downregulation of XIAP.

International journal of molecular medicine 20091101

Differentiation of SWO-38 glioma cells induced by CDA-2 is mediated by peroxisome proliferator-activated receptor gamma.

Journal of neuro-oncology 20091001

Salacia oblonga extract increases glucose transporter 4-mediated glucose uptake in L6 rat myotubes: role of mangiferin.

Clinical nutrition (Edinburgh, Scotland) 20091001

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

Molecular & cellular proteomics : MCP 20091001

Cognitive deficit in amyloid-beta-injected mice was improved by pretreatment with a low dose of telmisartan partly because of peroxisome proliferator-activated receptor-gamma activation.

Hypertension (Dallas, Tex. : 1979) 20091001

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nature chemical biology 20091001

Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests.

Behavioural pharmacology 20091001

Telmisartan inhibits cytokine-induced nuclear factor-kappaB activation independently of the peroxisome proliferator-activated receptor-gamma.

Hypertension research : official journal of the Japanese Society of Hypertension 20090901

Crosstalk between peroxisome proliferator-activated receptor-gamma and angiotensin II in renal tubular epithelial cells in IgA nephropathy.

Clinical immunology (Orlando, Fla.) 20090801

Nifedipine, a calcium channel blocker, inhibits advanced glycation end product (AGE)-elicited mesangial cell damage by suppressing AGE receptor (RAGE) expression via peroxisome proliferator-activated receptor-gamma activation.

Biochemical and biophysical research communications 20090724

Antagonist of peroxisome proliferator-activated receptor gamma induces cerebellar amyloid-beta levels and motor dysfunction in APP/PS1 transgenic mice.

Biochemical and biophysical research communications 20090703

Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail.

The Journal of nutritional biochemistry 20090701

Rosiglitazone and PPAR-gamma overexpression protect mitochondrial membrane potential and prevent apoptosis by upregulating anti-apoptotic Bcl-2 family proteins.

Journal of cellular physiology 20090701

Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells.

Journal of neuropathology and experimental neurology 20090701

Time-dependent vascular actions of cannabidiol in the rat aorta.

European journal of pharmacology 20090610

Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor.

American journal of physiology. Lung cellular and molecular physiology 20090601

Repressive effect of the phytoestrogen genistein on estradiol-induced uterine leiomyoma cell proliferation.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090601

Peroxisome-proliferator receptor gamma represses hepatic sex hormone-binding globulin expression.

Endocrinology 20090501

A rapid, PPAR-gamma-dependent effect of pioglitazone on the phosphorylation of MYPT.

American journal of physiology. Cell physiology 20090501

Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.

American journal of physiology. Heart and circulatory physiology 20090501

Inhibition of tumor necrosis factor-alpha-induced interleukin-6 expression by telmisartan through cross-talk of peroxisome proliferator-activated receptor-gamma with nuclear factor kappaB and CCAAT/enhancer-binding protein-beta.

Hypertension (Dallas, Tex. : 1979) 20090501

[Role of peroxisome proliferators-activated receptor-gamma in the chemical prevention therapy of sulindac for precancerous lesions of rats].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20090418

Effects of benzbromarone and allopurinol on adiponectin in vivo and in vitro.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090401

Apoptosis induced in HepG2 cells by the synthetic cannabinoid WIN: involvement of the transcription factor PPARgamma.

Biochimie 20090401

Rosiglitazone acts as a neuroprotectant in retinal cells via up-regulation of sestrin-1 and SOD-2.

Journal of neurochemistry 20090401

Anti-inflammatory effect of peroxisome proliferator activated receptor gamma on human dental pulp cells.

Journal of endodontics 20090401

Relaxin family peptide receptor 1 activation stimulates peroxisome proliferator-activated receptor gamma.

Annals of the New York Academy of Sciences 20090401

Telmisartan increases the permeability of endothelial cells through zonula occludens-1.

Biological & pharmaceutical bulletin 20090301

Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells.

World journal of gastroenterology 20090121

Rosiglitazone inhibits alpha4 nicotinic acetylcholine receptor expression in human lung carcinoma cells through peroxisome proliferator-activated receptor gamma-independent signals.

Molecular cancer therapeutics 20090101

Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation.

Cardiovascular diabetology 20090101

Niacin promotes cholesterol efflux through stimulation of the PPARgamma-LXRalpha-ABCA1 pathway in 3T3-L1 adipocytes.

Pharmacology 20090101

Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells.

PloS one 20090101

Direct rosiglitazone action on steroidogenesis and proinflammatory factor production in human granulosa-lutein cells.

Reproductive biology and endocrinology : RB&E 20090101

PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms.

Brain research 20081209

Tryptophan-containing dipeptide derivatives as potent PPARgamma antagonists: design, synthesis, biological evaluation, and molecular modeling.

European journal of medicinal chemistry 20081201

Cilostazol increases 3T3-L1 preadipocyte differentiation with improved glucose uptake associated with activation of peroxisome proliferator-activated receptor-gamma transcription.

Atherosclerosis 20081201

Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway.

Chinese medical journal 20081120

Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}.

Blood 20081115

Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression.

Oncology reports 20081101

Mechanisms underlying pioglitazone-mediated relaxation in isolated blood vessel.

Journal of pharmacological sciences 20081101

Pioglitazone attenuates tactile allodynia and thermal hyperalgesia in mice subjected to peripheral nerve injury.

Journal of pharmacological sciences 20081101

Telmisartan prevented cognitive decline partly due to PPAR-gamma activation.

Biochemical and biophysical research communications 20081024

Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats.

Immunology 20081001

Biomolecular characterization of human glioblastoma cells in primary cultures: differentiating and antiangiogenic effects of natural and synthetic PPARgamma agonists.

Journal of cellular physiology 20081001

Fisetin, morin and myricetin attenuate CD36 expression and oxLDL uptake in U937-derived macrophages.

Biochimica et biophysica acta 20081001

Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2.

Cancer letters 20080918

Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease.

The Journal of biological chemistry 20080912

Repression of interferon-gamma expression in T cells by Prospero-related homeobox protein.

Cell research 20080901

6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-alpha mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.

Biochemical and biophysical research communications 20080829

Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol.

Toxicology and applied pharmacology 20080815

Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma.

Cancer investigation 20080801

Neuroprotective effect of the new thiadiazolidinone NP00111 against oxygen-glucose deprivation in rat hippocampal slices: implication of ERK1/2 and PPARgamma receptors.

Experimental neurology 20080701

[Effects of activated PPARgamma on the expression of PTEN gene in pancreatic cancer cells].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20080701

[Effects of peroxisome proliferators-activated receptor-gamma on the function of the vital organs in rats with pancreatitis].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080601

Berberine inhibits the expression of TNFalpha, MCP-1, and IL-6 in AcLDL-stimulated macrophages through PPARgamma pathway.

Endocrine 20080601

CITED2 signals through peroxisome proliferator-activated receptor-gamma to regulate death of cortical neurons after DNA damage.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521

Peroxisome proliferator activated receptor gamma is not necessary for the development of LPS-induced tolerance in macrophages.

Immunology 20080501

Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid.

Rheumatology international 20080501

Neuroendocrine transdifferentiation induced by VPA is mediated by PPARgamma activation and confers resistance to antiblastic therapy in prostate carcinoma.

The Prostate 20080501

Effects of telmisartan, a unique angiotensin receptor blocker with selective peroxisome proliferator-activated receptor-gamma-modulating activity, on nitric oxide bioavailability and atherosclerotic change.

Journal of hypertension 20080501

Effect of troglitazone on CYP1A1 induction.

Toxicology 20080418

Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts.

British journal of pharmacology 20080401

[Pioglitazone inhibits dendritic cell adhesion and transmigration through down-regulation of dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin].

Zhonghua yi xue za zhi 20080325

Rosiglitazone stimulates the release and synthesis of insulin by enhancing GLUT-2, glucokinase and BETA2/NeuroD expression.

Biochemical and biophysical research communications 20080314

Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.

Hypertension (Dallas, Tex. : 1979) 20080301

PPARgamma-dependent and -independent effects of rosiglitazone on lipotoxic human pancreatic islets.

Biochemical and biophysical research communications 20080222

The peroxisome proliferator-activated receptor-gamma agonist 1,1-bis(3'-indolyl)-1-(p-trifluoromethylphenyl)methane suppresses manganese-induced production of nitric oxide in astrocytes and inhibits apoptosis in cocultured PC12 cells.

Journal of neuroscience research 20080215

Pigment epithelium-derived factor induces THP-1 macrophage apoptosis and necrosis by the induction of the peroxisome proliferator-activated receptor gamma.

Molecular immunology 20080201

15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor.

The Journal of pharmacology and experimental therapeutics 20080101

Rosiglitazone inhibits metastasis development of a murine mammary tumor cell line LMM3.

BMC cancer 20080101

The PPARgamma agonist FMOC-L-leucine protects both mature and immature brain.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101

Eicosapentaenoic acid inhibits interleukin-6 production in interleukin-1beta-stimulated C6 glioma cells through peroxisome proliferator-activated receptor-gamma.

Prostaglandins, leukotrienes, and essential fatty acids 20080101

PPARgamma: The Portrait of a Target Ally to Cancer Chemopreventive Agents.

PPAR research 20080101

Role of PPAR-gamma in the modulation of CD36 and FcgammaRII induced by LDL with low and high degrees of oxidation during the differentiation of the monocytic THP-1 cell line.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.

American journal of physiology. Endocrinology and metabolism 20071201

Peroxisome proliferator-activated receptor gamma agonist action of 3-methyl-1,2-cyclopentanedione.

Biochimica et biophysica acta 20071201

Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt.

Shock (Augusta, Ga.) 20071101

Peroxisome proliferator-activated receptor-gamma is involved in the control of renin gene expression.

Hypertension (Dallas, Tex. : 1979) 20071101

beta-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor gamma expression and reactive oxygen species production in MCF-7 cancer cells.

European journal of cancer (Oxford, England : 1990) 20071101

Comparison of vascular relaxation, lipolysis and glucose uptake by peroxisome proliferator-activated receptor-gamma activation in +db/+m and +db/+db mice.

European journal of pharmacology 20071015

Differential ability of a thiazolidinedione PPARgamma agonist to attenuate cytokine secretion in primary microglia and macrophage-like cells.

Journal of neurochemistry 20071001

A peroxisome proliferator-activated receptor gamma antagonist induces vimentin cleavage and inhibits invasion in high-grade hepatocellular carcinoma.

Oncology reports 20071001

Interleukin-10 is upregulated by nanomolar rosiglitazone treatment of mature dendritic cells and human CD4+ T cells.

Cytokine 20070901

Induction of apoptosis of human gastric carcinoma SGC-7901 cell line by 5, 7-dihydroxy-8-nitrochrysin in vitro.

World journal of gastroenterology 20070728

Desmethyl derivatives of indomethacin and sulindac as probes for cyclooxygenase-dependent biology.

ACS chemical biology 20070720

Synthesis, antimicrobial, and QSAR studies of substituted benzamides.

Bioorganic & medicinal chemistry 20070615

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

European journal of pharmacology 20070601

Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase.

Molecular pharmacology 20070601

Peroxisome proliferator-activated receptor-gamma antagonists exhibit potent antiproliferative effects versus many hematopoietic and epithelial cancer cell lines.

Anti-cancer drugs 20070601

IL-13 induces expression of CD36 in human monocytes through PPARgamma activation.

European journal of immunology 20070601

Does the inhibition of c-myc expression mediate the anti-tumor activity of PPAR's ligands in prostate cancer cell lines?

Archives of biochemistry and biophysics 20070601

Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma cells.

Acta pharmacologica Sinica 20070601

9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development.

Journal of immunology (Baltimore, Md. : 1950) 20070515

Role of mitogen-activated protein kinase (MAPK) in troglitazone-induced osteoblastic cell death.

Toxicology 20070505

Effects of curcumin on peroxisome proliferator-activated receptor gamma expression and nuclear translocation/redistribution in culture-activated rat hepatic stellate cells.

Chinese medical journal 20070505

Inhibitory effect of PPAR on the expression of EMMPRIN in macrophages and foam cells.

International journal of cardiology 20070502

Peroxisome proliferator-activated receptor gamma activation relieves expression of behavioral sensitization to methamphetamine in mice.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070501

PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells.

European journal of immunology 20070501

Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation.

American journal of physiology. Renal physiology 20070401

PGC-1alpha induces apoptosis in human epithelial ovarian cancer cells through a PPARgamma-dependent pathway.

Cell research 20070401

Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents.

Journal of neurochemistry 20070401

Rosiglitazone enhances fluorouracil-induced apoptosis of HT-29 cells by activating peroxisome proliferator-activated receptor gamma.

World journal of gastroenterology 20070314

Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats.

The Journal of pharmacology and experimental therapeutics 20070301

Upregulation of tumor necrosis factor-alpha expression by trans10-cis12 conjugated linoleic acid enhances phagocytosis of RAW macrophages via a peroxisome proliferator-activated receptor gamma-dependent pathway.

Cytokine 20070301

[Effect of peroxisome proliferators-activated receptor-gamma in the mechanisms of sulindac against large intestine carcinoma].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20070218

Resveratrol inhibits macrophage expression of EMMPRIN by activating PPARgamma.

Vascular pharmacology 20070201

1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes inhibit growth, induce apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through peroxisome proliferator-activated receptor gamma-independent pathways.

Molecular pharmacology 20070201

PPARgamma inhibitors reduce tubulin protein levels by a PPARgamma, PPARdelta and proteasome-independent mechanism, resulting in cell cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells.

International journal of cancer 20070201

Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate.

Toxicological sciences : an official journal of the Society of Toxicology 20070101

In utero nicotine exposure alters fetal rat lung alveolar type II cell proliferation, differentiation, and metabolism.

American journal of physiology. Lung cellular and molecular physiology 20070101

Potential role for peroxisome proliferator-activated receptor gamma in regulating luteal lifespan in the rat.

Reproduction (Cambridge, England) 20070101

Telmisartan, an angiotensin II type 1 receptor blocker, inhibits advanced glycation end-product (AGE)-induced monocyte chemoattractant protein-1 expression in mesangial cells through downregulation of receptor for AGEs via peroxisome proliferator-activated receptor-gamma activation.

The Journal of international medical research 20070101

Conjugated linoleic acid enhances glutathione synthesis and attenuates pathological signs in MRL/MpJ-Fas(lpr) mice.

Journal of lipid research 20061101

Ceramide induces apoptosis via a peroxisome proliferator-activated receptor gamma-dependent pathway.

Apoptosis : an international journal on programmed cell death 20061101

Phorbol ester potentiates the growth inhibitory effects of troglitazone via up-regulation of PPARgamma in A549 cells.

Biochemical and biophysical research communications 20061020

PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells.

The Journal of experimental medicine 20061002

Telmisartan downregulates angiotensin II type 1 receptor through activation of peroxisome proliferator-activated receptor gamma.

Cardiovascular research 20061001

Synthesis and evaluation of a bromine-76-labeled PPARgamma antagonist 2-bromo-5-nitro-N-phenylbenzamide.

Nuclear medicine and biology 20061001

Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma) induces cell death through MAPK-dependent mechanism in osteoblastic cells.

Toxicology and applied pharmacology 20060901

Pioglitazone induces apoptosis of macrophages in human adipose tissue.

Journal of lipid research 20060901

Inhibition of peroxisome proliferator-activated receptor gamma activity in esophageal carcinoma cells results in a drastic decrease of invasive properties.

Cancer science 20060901

PPARgamma-regulated tight junction development during human urothelial cytodifferentiation.

Journal of cellular physiology 20060801

Rosiglitazone ameliorates cisplatin-induced renal injury in mice.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801

Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators.

Protein science : a publication of the Protein Society 20060801

Troglitazone acutely inhibits protein synthesis in endothelial cells via a novel mechanism involving protein phosphatase 2A-dependent p70 S6 kinase inhibition.

American journal of physiology. Cell physiology 20060801

Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation.

Molecular pharmacology 20060701

The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma.

Critical care medicine 20060701

A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage.

Annals of surgery 20060701

Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1alpha in allergic airway disease of mice.

The Journal of allergy and clinical immunology 20060701

[Resveratrol inhibits expression of EMMPRIN from macrophages].

Yao xue xue bao = Acta pharmaceutica Sinica 20060701

Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo.

Biochemical pharmacology 20060628

Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation.

Endocrinology 20060601

Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, prevents hyperoxia-induced neonatal rat lung injury in vivo.

Pediatric pulmonology 20060601

PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression.

Acta pharmacologica Sinica 20060601

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Differential modulation of cell cycle, apoptosis and PPARgamma2 gene expression by PPARgamma agonists ciglitazone and 9-hydroxyoctadecadienoic acid in monocytic cells.

Prostaglandins, leukotrienes, and essential fatty acids 20060501

Further characterization of the time-dependent vascular effects of delta9-tetrahydrocannabinol.

The Journal of pharmacology and experimental therapeutics 20060401

Peroxisome proliferator-activated receptor-gamma antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia.

Critical care medicine 20060401

Effects of rosiglitazone and metformin on pancreatic beta cell gene expression.

Diabetologia 20060401

Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.

Journal of neurochemistry 20060401

Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells.

Development, growth & differentiation 20060401

Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms.

The Journal of biological chemistry 20060127

Involvement of PPARgamma in oxidative stress-mediated prostaglandin E(2) production in SZ95 human sebaceous gland cells.

The Journal of investigative dermatology 20060101

15-Deoxy-Delta(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues.

Placenta 20060101

Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma.

American journal of nephrology 20060101

Quantitative characterization of 15-deoxy-delta(12,14)-prostaglandin J2 in regulating EGFPSmad2 translocation in CHO cells through PPARgamma/TGFbeta/Smad2 pathway.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101

Environmental chemical tributyltin augments adipocyte differentiation.

Toxicology letters 20051215

Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces pulmonary inflammatory response in a rat model of endotoxemia.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20051101

Accelerated recovery of 5-fluorouracil-damaged bone marrow after rosiglitazone treatment.

European journal of pharmacology 20051017

5-Oxo-ETE analogs and the proliferation of cancer cells.

Biochimica et biophysica acta 20051001

Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, reduces acute lung injury in endotoxemic rats.

Critical care medicine 20051001

Peroxisome proliferator-activated receptor-gamma ligands suppress fibronectin gene expression in human lung carcinoma cells: involvement of both CRE and Sp1.

American journal of physiology. Lung cellular and molecular physiology 20050901

Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation.

Journal of neurochemistry 20050901

Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms.

Arteriosclerosis, thrombosis, and vascular biology 20050901

Differential responses of PPARalpha, PPARdelta, and PPARgamma reporter cell lines to selective PPAR synthetic ligands.

Analytical biochemistry 20050901

The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion.

Kidney international 20050801

Salutary effects of androstenediol on hepatic function after trauma-hemorrhage are mediated via peroxisome proliferators-activated receptor gamma.

Surgery 20050801

Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation.

European journal of pharmacology 20050711

Nanomolar and micromolar effects of 15-deoxy-delta 12,14-prostaglandin J2 on amnion-derived WISH epithelial cells: differential roles of peroxisome proliferator-activated receptors gamma and delta and nuclear factor kappa B.

Molecular pharmacology 20050701

Peroxisome proliferator-activated receptor-gamma agonists suppress adrenocortical tumor cell proliferation and induce differentiation.

The Journal of clinical endocrinology and metabolism 20050701

Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation.

The Journal of biological chemistry 20050603

PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis.

American journal of physiology. Lung cellular and molecular physiology 20050601

Critical role of peroxisome proliferator-activated receptor gamma on anoikis and invasion of squamous cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research 20050601

Selective activation of PPARgamma in breast, colon, and lung cancer cell lines.

Molecular and cellular endocrinology 20050512

The cardioprotective effects of preconditioning with endotoxin, but not ischemia, are abolished by a peroxisome proliferator-activated receptor-gamma antagonist.

The Journal of pharmacology and experimental therapeutics 20050501

HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo.

Circulation 20050322

[Effect of peroxisome proliferation activated receptor-gamma on neuronal cell death induced by hypoxia and ischemia in rats in vitro and in vivo].

Zhonghua yi xue za zhi 20050316

Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells.

Cancer research 20050315

Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism.

Arthritis and rheumatism 20050301

Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor.

Cancer research 20050201

Pituitary resistin gene expression is upregulated in vitro and in vivo by dexamethasone but is unaffected by rosiglitazone.

Neuroendocrinology 20050101

Upregulation of connexin 43 by retinoids but not by non-provitamin A carotenoids requires RARs.

Nutrition and cancer 20050101

A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.

Analytical biochemistry 20041215

Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins.

Endocrinology 20041201

GW9662, a potent antagonist of PPARgamma, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARgamma agonist rosiglitazone, independently of PPARgamma activation.

British journal of pharmacology 20041201

Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201

Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism.

Journal of lipid research 20041101

Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes.

Molecular pharmacology 20041101

Overexpression of short heterodimer partner recovers impaired glucose-stimulated insulin secretion of pancreatic beta-cells overexpressing UCP2.

The Journal of endocrinology 20041001

15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria.

European journal of pharmacology 20040913

Genistein inhibits expressions of NADPH oxidase p22phox and angiotensin II type 1 receptor in aortic endothelial cells from stroke-prone spontaneously hypertensive rats.

Hypertension research : official journal of the Japanese Society of Hypertension 20040901

Nonsteroidal anti-inflammatory drugs potentiate 1-methyl-4-phenylpyridinium (MPP+)-induced cell death by promoting the intracellular accumulation of MPP+ in PC12 cells.

The Journal of pharmacology and experimental therapeutics 20040801

The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines.

International journal of oncology 20040801

Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor gamma and sterol regulatory element-binding protein in the regulation of adipogenesis.

The Journal of biological chemistry 20040604

Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.

The Journal of biological chemistry 20040521

Fatty acid-mediated inhibition of IL-12 production by murine macrophages is independent of PPARgamma.

The British journal of nutrition 20040501

Cardiovascular drugs inhibit MMP-9 activity from human THP-1 macrophages.

DNA and cell biology 20040501

Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme.

Journal of cell science 20040415

Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15-deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin.

Critical care medicine 20040301

Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1.

The Journal of biological chemistry 20040220

Endogenous ligands of PPAR-gamma reduce the liver injury in haemorrhagic shock.

European journal of pharmacology 20040220

Transcriptional inactivation of STAT3 by PPARgamma suppresses IL-6-responsive multiple myeloma cells.

Immunity 20040201

PPARgamma mediates NSAIDs-induced upregulation of TFF2 expression in gastric epithelial cells.

FEBS letters 20040130

Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma.

The American journal of pathology 20040101

Inhibition of cell proliferation by potential peroxisome proliferator-activated receptor (PPAR) gamma agonists and antagonists.

Anticancer research 20040101

Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway.

The Journal of pharmacology and experimental therapeutics 20031101

Induction of apoptosis by mono(2-ethylhexyl)phthalate (MEHP) in U937 cells.

Toxicology letters 20031015

PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes.

Hypertension (Dallas, Tex. : 1979) 20031001

PPARgamma ligands induce prostaglandin production in vascular smooth muscle cells: indomethacin acts as a peroxisome proliferator-activated receptor-gamma antagonist.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001

PPAR gamma activators induce growth arrest and process extension in B12 oligodendrocyte-like cells and terminal differentiation of cultured oligodendrocytes.

Journal of neuroscience research 20030515

The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs.

Cancer research 20030115

Peroxisome proliferator-activated receptor-gamma in thyroid eye disease: contraindication for thiazolidinedione use?

The Journal of clinical endocrinology and metabolism 20030101

Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells.

Cellular and molecular life sciences : CMLS 20030101

Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

Biochemistry 20020528

Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

The Journal of biological chemistry 20020419