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Ginkgolic Acid

CAS No.:
22910-60-7
Catalog Number:
AG002LGH
Molecular Formula:
C22H34O3
Molecular Weight:
346.5036
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥95%
1 week
United States
$125
- +
5mg
99%
1 week
United States
$315
- +
10mg
99%
1 week
United States
$482
- +
Product Description
Catalog Number:
AG002LGH
Chemical Name:
Ginkgolic Acid
CAS Number:
22910-60-7
Molecular Formula:
C22H34O3
Molecular Weight:
346.5036
MDL Number:
MFCD03093717
IUPAC Name:
2-hydroxy-6-[(Z)-pentadec-8-enyl]benzoic acid
InChI:
InChI=1S/C22H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h7-8,15,17-18,23H,2-6,9-14,16H2,1H3,(H,24,25)/b8-7-
InChI Key:
YXHVCZZLWZYHSA-FPLPWBNLSA-N
SMILES:
CCCCCC/C=C\CCCCCCCc1cccc(c1C(=O)O)O
Properties
Complexity:
364  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
346.251g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
346.511g/mol
Monoisotopic Mass:
346.251g/mol
Rotatable Bond Count:
14  
Topological Polar Surface Area:
57.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
8.5  
Literature
Title Journal
Pharmacological inhibition of SUMO-1 with ginkgolic acid alleviates cardiac fibrosis induced by myocardial infarction in mice. Toxicology and applied pharmacology 20180415
Metabolic profiling of the hepatotoxicity and nephrotoxicity of Ginkgolic acids in rats using ultra-performance liquid chromatography-high-definition mass spectrometry. Chemico-biological interactions 20170801
Non-specific SIRT inhibition as a mechanism for the cytotoxicity of ginkgolic acids and urushiols. Toxicology letters 20140902
Small ubiquitin-related modifier-1 modification regulates all-trans-retinoic acid-induced differentiation via stabilization of retinoic acid receptor α. The FEBS journal 20140701
Efficacy of ginkgolic acids against Cryptosporidium andersoni in cell culture. Parasitology research 20111101
Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples. Journal of agricultural and food chemistry 20111026
Development of high performance liquid chromatography/electrospray ionization mass spectrometry for assay of ginkgolic acid (15:1) in rat plasma and its application to pharmacokinetics study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015
Antitumor effects of ginkgolic acid in human cancer cell occur via cell cycle arrest and decrease the Bcl-2/Bax ratio to induce apoptosis. Chemotherapy 20100101
Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange. Rapid communications in mass spectrometry : RCM 20090701
Cytotoxicity of ginkgolic acid in HepG2 cells and primary rat hepatocytes. Toxicology letters 20090622
[Studies on dynamic change of total ginkgolic acids in Ginkgo biloba leaves of different aged trees and different collecting seasons]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401
Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. Chemistry & biology 20090227
[Determination of ginkgolic acids in Ginkgo biloba leaves by gas chromatography with on-line pyrolytic methylation]. Se pu = Chinese journal of chromatography 20081101
Anti-Toxoplasma gondii activity of GAS in vitro. Journal of ethnopharmacology 20080813
Design and evaluation of anacardic acid derivatives as anticavity agents. European journal of medicinal chemistry 20080601
[Preparation of five ginkgolic acid monomers and their molluscicidal effects against Oncomelania hupensis]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20070801
[Study on anti-bacterium activity of ginkgolic acids and their momomers]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040901
Quantification of allergenic urushiols in extracts of Ginkgo biloba leaves, in simple one-step extracts and refined manufactured material (EGb 761). Phytochemical analysis : PCA 20040101
Quantitative analysis of ginkgolic acids from Ginkgo leaves and products using 1H-NMR. Phytochemical analysis : PCA 20040101
[Determination of ginkgolic acids in Ginkgo biloba extract and its preparations by high performance liquid chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica 20031101
[Isolation and HPLC analysis of ginkgolic acid]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030801
In vitro evaluation of the cytotoxic potential of alkylphenols from Ginkgo biloba L. Toxicology 20020815
[Determination of ginkgolic acids by high performance liquid chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica 20020701
Pharmaceutical quality of different Ginkgo biloba brands. The Journal of pharmacy and pharmacology 20020501
Reversed-phase argentation high-performance liquid chromatography in phytochemical analysis of ginkgolic acids in leaves from Ginkgo biloba L. Journal of chromatography. A 20020118
Ginkgolic acids induce neuronal death and activate protein phosphatase type-2C. European journal of pharmacology 20011026
Preparative isolation and dual column high-performance liquid chromatography of ginkgolic acids from Ginkgo biloba. Journal of chromatography. A 20010928
[Separation and quantitative analysis of ginkgolic acids from Ginkgo biloba leaves by reverse phase argentation high performance liquid chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica 20010801
Determination of ginkgolic acids from Ginkgo biloba leaves by reversed-phase argentation high performance liquid chromatography. Se pu = Chinese journal of chromatography 20010501
Evidence for toxic effects of alkylphenols from Ginkgo biloba in the hen's egg test (HET). Phytomedicine : international journal of phytotherapy and phytopharmacology 20010301
Dr. Gordon Bates: a personal war against VD. Dimensions in health service 19751201
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