2-Propanesulfonamide, N-[2-(4'-cyano[1,1'-biphenyl]-4-yl)propyl]-
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The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf⁺/⁻ heterozygous null mice. | Neuropharmacology 20120101 |
Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20101215 |
Positive allosteric modulators of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor. | Journal of medicinal chemistry 20101028 |
Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction. | Behavioural brain research 20100901 |
AMPA receptor potentiation can prevent ethanol-induced intoxication. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080601 |
Molecular mechanisms of neurite growth with AMPA receptor potentiation. | Neuropharmacology 20070201 |
Pharmacological characterization of cGMP regulation by the biarylpropylsulfonamide class of positive, allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. | The Journal of pharmacology and experimental therapeutics 20061001 |
A novel class of AMPA receptor allosteric modulators. Part 1: design, synthesis, and SAR of 3-aryl-4-cyano-5-substituted-heteroaryl-2-carboxylic acid derivatives. | Bioorganic & medicinal chemistry letters 20061001 |
Targeting neurological receptors. | IDrugs : the investigational drugs journal 20051201 |
Examining the neural targets of the AMPA receptor potentiator LY404187 in the rat brain using pharmacological magnetic resonance imaging. | Psychopharmacology 20050801 |
The AMPA receptor potentiator LY404187 increases cerebral glucose utilization and c-fos expression in the rat. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20041001 |
Neurotrophic actions of the novel AMPA receptor potentiator, LY404187, in rodent models of Parkinson's disease. | European journal of pharmacology 20040220 |
Multiple molecular determinants for allosteric modulation of alternatively spliced AMPA receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031126 |
Chronic AMPA receptor potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus. | Neuropharmacology 20030601 |
Design and synthesis of a novel series of 1,2-disubstituted cyclopentanes as small, potent potentiators of 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid (AMPA) receptors. | Journal of medicinal chemistry 20020509 |
Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator. | The Journal of pharmacology and experimental therapeutics 20010701 |
Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro. | Neuropharmacology 20010601 |
Pharmacological effects of AMPA receptor potentiators LY392098 and LY404187 on rat neuronal AMPA receptors in vitro. | Neuropharmacology 20010601 |
Potentiation of responses to AMPA on central neurones by LY392098 and LY404187 in vivo. | Neuropharmacology 20010601 |