Triptolide-induced oxidative stress involved with Nrf2 contribute to cardiomyocyte apoptosis through mitochondrial dependent pathways.

Toxicology letters 20141104

Resveratrol induced ER expansion and ER caspase-mediated apoptosis in human nasopharyngeal carcinoma cells.

Apoptosis : an international journal on programmed cell death 20140301

Purinergic P2X7 receptors mediate cell death in mouse cerebellar astrocytes in culture.

The Journal of pharmacology and experimental therapeutics 20131201

PF-04691502 triggers cell cycle arrest, apoptosis and inhibits the angiogenesis in hepatocellular carcinoma cells.

Toxicology letters 20130704

Newly synthesized quinazolinone HMJ-38 suppresses angiogenetic responses and triggers human umbilical vein endothelial cell apoptosis through p53-modulated Fas/death receptor signaling.

Toxicology and applied pharmacology 20130601

Irinotecan induces senescence and apoptosis in colonic cells in vitro.

Toxicology letters 20121002

Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis.

Molecular biology reports 20121001

Emodin induces embryonic toxicity in mouse blastocysts through apoptosis.

Toxicology 20120904

Multi-walled carbon nanotubes induce apoptosis via mitochondrial pathway and scavenger receptor.

Toxicology in vitro : an international journal published in association with BIBRA 20120901

Fluorescence-quenching-based homogeneous caspase-3 activity assay using photon upconversion.

Analytica chimica acta 20120506

Autophagy induced by baicalin involves downregulation of CD147 in SMMC-7721 cells in vitro.

Oncology reports 20120401

Evaluation of differential representative values between Chinese hamster cells and human lymphocytes in mitomycin C-induced cytogenetic assays and caspase-3 activity.

Toxicology and industrial health 20120301

Involvement of oxidative stress-induced ERK/JNK activation in the Cu(2+)/pyrrolidine dithiocarbamate complex-triggered mitochondria-regulated apoptosis in pancreatic β-cells.

Toxicology letters 20120205

5-Phenylselenyl- and 5-methylselenyl-methyl-2'-deoxyuridine induce oxidative stress, DNA damage, and caspase-2-dependent apoptosis in cancer cells.

Apoptosis : an international journal on programmed cell death 20120201

The apoptotic effects of the flavonoid N101-2 in human cervical cancer cells.

Toxicology in vitro : an international journal published in association with BIBRA 20120201

J7, a methyl jasmonate derivative, enhances TRAIL-mediated apoptosis through up-regulation of reactive oxygen species generation in human hepatoma HepG2 cells.

Toxicology in vitro : an international journal published in association with BIBRA 20120201

Preparation and characterization of biocompatible chitosan nanoparticles for targeted brain delivery of peptides.

Methods in molecular biology (Clifton, N.J.) 20120101

Thimerosal-induced apoptosis in mouse C2C12 myoblast cells occurs through suppression of the PI3K/Akt/survivin pathway.

PloS one 20120101

Okadaic acid induces apoptosis through the PKR, NF-κB and caspase pathway in human osteoblastic osteosarcoma MG63 cells.

Toxicology in vitro : an international journal published in association with BIBRA 20111201

Plumbagin and juglone induce caspase-3-dependent apoptosis involving the mitochondria through ROS generation in human peripheral blood lymphocytes.

Free radical biology & medicine 20111201

Cytotoxicity of synthetic cannabinoids found in 'Spice' products: the role of cannabinoid receptors and the caspase cascade in the NG 108-15 cell line.

Toxicology letters 20111110

Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease.

Toxicology and applied pharmacology 20111101

Manganese nanoparticle activates mitochondrial dependent apoptotic signaling and autophagy in dopaminergic neuronal cells.

Toxicology and applied pharmacology 20111101

α7 Nicotinic receptor activation reduces β-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signaling.

Journal of neurochemistry 20111101

Defect in mevalonate pathway induces pyroptosis in Raw 264.7 murine monocytes.

Apoptosis : an international journal on programmed cell death 20110901

Presence of cleaved caspase 3 in swine embryos of different developmental capacities produced by parthenogenetic activation.

Molecular reproduction and development 20110901

Ginsenoside Rg3 inhibit hepatocellular carcinoma growth via intrinsic apoptotic pathway.

World journal of gastroenterology 20110821

The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells.

The Journal of biological chemistry 20110729

Blocking caspase-3-dependent pathway preserves hair cells from salicylate-induced apoptosis in the guinea pig cochlea.

Molecular and cellular biochemistry 20110701

Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation.

Neuro-oncology 20110301

Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways.

Chemical research in toxicology 20110114

Atorvastatin acts synergistically with N-acetyl cysteine to provide therapeutic advantage against Fas-activated erythrocyte apoptosis during chronic arsenic exposure in rats.

Toxicology and applied pharmacology 20110101

17beta-estradiol attenuates programmed cell death in cortical pericontusional zone following traumatic brain injury via upregulation of ERalpha and inhibition of caspase-3 activation.

Neurochemistry international 20110101

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.

Nature neuroscience 20110101

Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells.

Toxicology letters 20101215

Haplophytin-A induces caspase-8-mediated apoptosis via the formation of death-inducing signaling complex in human promyelocytic leukemia HL-60 cells.

Chemico-biological interactions 20101205

Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2.

Apoptosis : an international journal on programmed cell death 20101201

[Experimental study on treatment of rabbits optic nerve injury with Caspase-3 inhibitor z-DEVD-fmk].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20101201

1-(3',4',5'-Trimethoxyphenyl)-3-(3'',4''-dimethoxy-2''-hydroxyphenyl)-propane with microtubule-depolymerizing ability induces G2/M phase arrest and apoptosis in HepG2 cells.

Chemico-biological interactions 20101006

8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK.

World journal of gastroenterology 20100721

Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway.

Chemical research in toxicology 20100719

Matrine induces apoptosis of human multiple myeloma cells via activation of the mitochondrial pathway.

Leukemia & lymphoma 20100701

Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.

Toxicology and applied pharmacology 20100615

Heat shock protein 70 and cellular disturbances in cochlear cisplatin ototoxicity model.

The Journal of laryngology and otology 20100601

Sulfur mustard induces apoptosis in lung epithelial cells via a caspase amplification loop.

Toxicology 20100527

Human cytomegalovirus induces caspase-dependent apoptosis of megakaryocytic CHRF-288-11 cells by activating the JNK pathway.

International journal of hematology 20100501

Topotecan triggers apoptosis in p53-deficient cells by forcing degradation of XIAP and survivin thereby activating caspase-3-mediated Bid cleavage.

The Journal of pharmacology and experimental therapeutics 20100101

Okadaic acid induces DNA fragmentation via caspase-3-dependent and caspase-3-independent pathways in Chinese hamster ovary (CHO)-K1 cells.

The FEBS journal 20100101

Androgens induce dopaminergic neurotoxicity via caspase-3-dependent activation of protein kinase Cdelta.

Endocrinology 20091201

Feedback regulation of mitochondria by caspase-9 in the B cell receptor-mediated apoptosis.

Scandinavian journal of immunology 20091201

Protein kinase C-delta mediates down-regulation of heterogeneous nuclear ribonucleoprotein K protein: involvement in apoptosis induction.

Experimental cell research 20091115

A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20091104

The anti-apoptotic effects of caspase inhibitors on propyl gallate-treated HeLa cells in relation to reactive oxygen species and glutathione levels.

Archives of toxicology 20090901

KLF4 suppresses HDACi induced caspase activation and the SAPK pathway by targeting p57(Kip2).

Apoptosis : an international journal on programmed cell death 20090901

Reactive oxygen species-induced cell death of rat primary astrocytes through mitochondria-mediated mechanism.

Journal of cellular biochemistry 20090801

Involvement of both extrinsic and intrinsic apoptotic pathways in apoptosis induced by genistein in human cervical cancer cells.

Annals of the New York Academy of Sciences 20090801

Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells.

Chemico-biological interactions 20090715

Induction of apoptosis in human lung carcinoma cells by the water extract of Panax notoginseng is associated with the activation of caspase-3 through downregulation of Akt.

International journal of oncology 20090701

PU.1, a novel caspase-3 substrate, partially contributes to chemotherapeutic agents-induced apoptosis in leukemic cells.

Biochemical and biophysical research communications 20090508

Studies of learning and memory processes in adult rats in conditions of intracerebral administration of caspase inhibitors.

Neuroscience and behavioral physiology 20090501

Erythropoietin protects retinal pigment epithelial cells from oxidative damage.

Free radical biology & medicine 20090415

Resveratrol regulates the expression of NHE-1 by repressing its promoter activity: critical involvement of intracellular H2O2 and caspases 3 and 6 in the absence of cell death.

The international journal of biochemistry & cell biology 20090401

Caspase-dependent molecular mechanisms of anti-human DR5 monoclonal antibody mDRA-6 inducing apoptosis of human leukemia Jurkat cells.

Ai zheng = Aizheng = Chinese journal of cancer 20090201

Natural activation of caspase-3 is required for the development of operant behavior in postnatal ontogenesis.

Neuroscience and behavioral physiology 20090101

The roles of endoplasmic reticulum stress and Ca2+ on rhein-induced apoptosis in A-549 human lung cancer cells.

Anticancer research 20090101

Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.

BMC cancer 20090101

Caspase inhibition attenuates accumulation of beta-amyloid by reducing beta-secretase production and activity in rat brains after stroke.

Neurobiology of disease 20081201

Induction of apoptosis by aqueous extract of Cordyceps militaris through activation of caspases and inactivation of Akt in human breast cancer MDA-MB-231 Cells.

Journal of microbiology and biotechnology 20081201

Neuroprotective effects of caspase-3 inhibition on functional recovery and tissue sparing after acute spinal cord injury.

Spine 20081001

Role of Bcl-2 family members in caspase-3/9-dependent apoptosis during Pseudomonas aeruginosa infection in U937 cells.

Apoptosis : an international journal on programmed cell death 20080601

Arsenic trioxide decreases AKT protein in a caspase-dependent manner.

Molecular cancer therapeutics 20080601

[Study of learning and memory processes in adult rats under conditions of intracerebral caspases inhibitors administration].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20080401

Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK.

Toxicology and applied pharmacology 20080301

Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons.

Experimental brain research 20080301

Role of calpain and caspase in beta-amyloid-induced cell death in rat primary septal cultured neurons.

Neuropharmacology 20080301

Doxorubicin induces biphasic neurotoxicity to rat cortical neurons.

Neurotoxicology 20080301

The most widespread desmosomal cadherin, desmoglein 2, is a novel target of caspase 3-mediated apoptotic machinery.

Journal of cellular biochemistry 20080201

Exogenous Hsc70, but not thermal preconditioning, confers protection to motoneurons subjected to oxidative stress.

Developmental neurobiology 20080101

Jaceosidin induces apoptosis in human ovary cancer cells through mitochondrial pathway.

Journal of biomedicine & biotechnology 20080101

Involvement of both tumor necrosis factor-alpha-induced necrosis and p53-mediated caspase-dependent apoptosis in nephrotoxicity of cisplatin.

Apoptosis : an international journal on programmed cell death 20071001

Organophosphorus pesticides induce apoptosis in human NK cells.

Toxicology 20070924

Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells.

International immunopharmacology 20070801

An L-tyrosine derivative and PPARgamma agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells.

Toxicological sciences : an official journal of the Society of Toxicology 20070701

Protective effects of myricetin and related flavonols against A2E and light mediated-cell death in bovine retinal primary cell culture.

Experimental eye research 20070701

Apoptotic signaling induces hyperpermeability following hemorrhagic shock.

American journal of physiology. Heart and circulatory physiology 20070601

Central injection of caspase inhibitors facilitates the formation of freezing behavior in rats.

Bulletin of experimental biology and medicine 20070501

GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals.

Biogerontology 20070401

Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts.

European journal of pharmacology 20070322

Radio-responsive gene therapy for malignant glioma cells without the radiosensitive promoter: Caspase-3 gene therapy combined with radiation.

Cancer letters 20070208

PD98059 triggers G1 arrest and apoptosis in human leukemic U937 cells through downregulation of Akt signal pathway.

International immunopharmacology 20070101

Amyloid-beta peptide affects the oxygen dependence of erythrocyte metabolism: a role for caspase 3.

The international journal of biochemistry & cell biology 20070101

Mountain grown ginseng induces apoptosis in HL-60 cells and its mechanism have little relation with TNF-alpha production.

The American journal of Chinese medicine 20070101

Resveratrol inhibits IL-1 beta-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro.

Annals of the New York Academy of Sciences 20070101

[Developmental caspase-3 activation in the rat hippocampus is involved in the maturation of instrumental behavior].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20070101

p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation.

Cancer research 20061201

[The role of caspase-3 in rapamycin-induced apoptosis of hepatocellular carcinoma BEL-7402 cells].

Ai zheng = Aizheng = Chinese journal of cancer 20061201

Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells.

Kidney international 20061001

Long-term potentiation in the hippocampus in conditions of inhibition of caspase-3: analysis of facilitation in paired-pulse stimulation.

Neuroscience and behavioral physiology 20061001

Effect of delta-elemene on Hela cell lines by apoptosis induction.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061001

Advanced glycation end-products induce apoptosis involving the signaling pathways of oxidative stress in bovine retinal pericytes.

Life sciences 20060808

Correlation of apoptotic potential of simple oxiranes with cytotoxicity.

Toxicology in vitro : an international journal published in association with BIBRA 20060801

Chlorpyrifos induces apoptosis in human monocyte cell line U937.

Toxicology 20060725

Sarco/endoplasmic reticulum Ca2+ATPase type 3 isoforms (SERCA3b and SERCA3f): distinct roles in cell adhesion and ER stress.

Biochemical and biophysical research communications 20060714

Initiation of apoptosis and autophagy by photodynamic therapy.

Lasers in surgery and medicine 20060601

Cadmium-induced apoptosis in murine macrophages is antagonized by antioxidants and caspase inhibitors.

Journal of toxicology and environmental health. Part A 20060601

Inhibition of calpain and caspase-3 prevented apoptosis and preserved electrophysiological properties of voltage-gated and ligand-gated ion channels in rat primary cortical neurons exposed to glutamate.

Neuroscience 20060512

Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases.

Journal of hepatology 20060501

Induction of apoptosis by carbazole alkaloids isolated from Murraya koenigii.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20060501

E-cadherin and its downstream catenins are proteolytically cleaved in human HaCaT keratinocytes exposed to UVB.

Experimental dermatology 20060401

[Effects of caspase-3 inhibitor on the neuronal apoptosis in rat cerebral cortex after ischemia-reperfusion injury].

Zhonghua bing li xue za zhi = Chinese journal of pathology 20060301

Role of apoptotic signaling pathway in metabolic disturbances occurring in liver tissue after cryopreservation: Study on rat precision-cut liver slices.

Life sciences 20060227

Apoptosis induced by atRA in MEPM cells is mediated through activation of caspase and RAR.

Toxicological sciences : an official journal of the Society of Toxicology 20060201

Cleavage of focal adhesion proteins and PKCdelta during lovastatin-induced apoptosis in spontaneously immortalized rat brain neuroblasts.

The FEBS journal 20060101

Nuclear caspase-3 and caspase-7 activation, and poly(ADP-ribose) polymerase cleavage are early events in camptothecin-induced apoptosis.

Apoptosis : an international journal on programmed cell death 20060101

Caspase-like activity is essential for long-term synaptic plasticity in the terrestrial snail Helix.

The European journal of neuroscience 20060101

Trimidox induces apoptosis via cytochrome c release in NALM-6 human B cell leukaemia cells.

Basic & clinical pharmacology & toxicology 20060101

[Effects of intracerebroventricular administration of a caspase-3 inhibitor Z-DEVD-FMK on behavior of rats].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20060101

Molecular mechanism of matrine-induced apoptosis in leukemia K562 cells.

The American journal of Chinese medicine 20060101

Molecular mechanisms of hexavalent chromium-induced apoptosis in human bronchoalveolar cells.

American journal of respiratory cell and molecular biology 20051201

Contribution of reactive oxygen species and caspase-3 to apoptosis and attenuated ICAM-1 expression by paclitaxel-treated MDA-MB-435 breast carcinoma cells.

International journal of oncology 20051201

[Inducement effect of Meisoindigo on apoptosis of leukemia cell line HL-60 and its mechanism].

Ai zheng = Aizheng = Chinese journal of cancer 20051201

Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress.

Proceedings of the National Academy of Sciences of the United States of America 20051122

Caspase-3 is required in the apoptotic disintegration of the nuclear matrix.

Experimental cell research 20051115

The neuroprotective effects of z-DEVD.fmk, a caspase-3 inhibitor, on traumatic spinal cord injury in rats.

Surgical neurology 20050901

Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.

European journal of pharmacology 20050822

Nonoxynol-9 induces apoptosis of endometrial explants by both caspase-dependent and -independent apoptotic pathways.

Biology of reproduction 20050801

Increased anticancer activity of the thymidylate synthase inhibitor BGC9331 combined with the topoisomerase I inhibitor SN-38 in human colorectal and breast cancer cells: induction of apoptosis and ROCK cleavage through caspase-3-dependent and -independent mechanisms.

International journal of oncology 20050801

[Effects of caspase-3 inhibition on long-term potentiation in the hippocampus: analysis of paired pulse facilitation].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20050801

Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor.

International journal of pharmaceutics 20050725

Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium.

The Biochemical journal 20050715

Phosphatase-1 and -2A inhibition modulates apoptosis in human osteoarthritis chondrocytes independently of nitric oxide production.

Annals of the rheumatic diseases 20050701

The phospholipid scramblase PLSCR1 increases UV induced apoptosis primarily through the augmentation of the intrinsic apoptotic pathway and independent of direct phosphorylation by protein kinase C delta.

Biochimica et biophysica acta 20050415

Resveratrol-induced apoptotic death in human U251 glioma cells.

Molecular cancer therapeutics 20050401

Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines.

Molecular cancer therapeutics 20050401

E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation.

Molecular cancer research : MCR 20050401

PRAM-1 potentiates arsenic trioxide-induced JNK activation.

The Journal of biological chemistry 20050311

Inhibition of caspases alleviates gentamicin-induced cochlear damage in guinea pigs.

Auris, nasus, larynx 20050301

[Mechanism of apoptosis induced by specific COX-2 inhibitor SC236 in gastric cancer cells].

Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050301

Central administration of a caspase inhibitor impairs shuttle-box performance in rats.

Neuroscience 20050101

Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26.

Bioconjugate chemistry 20050101

Incorporation of branched-chain fatty acid into cellular lipids and caspase-independent apoptosis in human breast cancer cell line, SKBR-3.

Lipids in health and disease 20050101

Pseudolaric acid B induces apoptosis via activation of c-Jun N-terminal kinase and caspase-3 in HeLa cells.

Experimental & molecular medicine 20041231

Adenine deoxynucleotides fludarabine and cladribine induce apoptosis in a CD95/Fas receptor, FADD and caspase-8-independent manner by activation of the mitochondrial cell death pathway.

Oncogene 20041216

Involvement of apoptosis in disruption of developmental competence of bovine oocytes by heat shock during maturation.

Biology of reproduction 20041201

Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.

Annals of the New York Academy of Sciences 20041201

Caspase 3 inhibition improves survival and reduces early graft injury after ischemia and reperfusion in rat liver transplantation.

Transplantation 20041115

Inhibition of caspase-3 blocks long-term potentiation in hippocampal slices.

Neuroscience and behavioral physiology 20041101

Extracellular signal-regulated kinase activation and Bcl-2 downregulation mediate apoptosis after gemcitabine treatment partly via a p53-independent pathway.

European journal of pharmacology 20041019

Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism.

Carcinogenesis 20041001

Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20041001

Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways.

Cell death and differentiation 20040901

6-Hydroxydopamine induces dopaminergic cell degeneration via a caspase-9-mediated apoptotic pathway that is attenuated by caspase-9dn expression.

Journal of neuroscience research 20040901

Involvement of caspase-10 in advanced glycation end-product-induced apoptosis of bovine retinal pericytes in culture.

Biochimica et biophysica acta 20040804

Caspase-3 inhibitor prevents apoptosis of human islets immediately after isolation and improves islet graft function.

Pancreas 20040801

Role of glutathione in dimethylarsinic acid-induced apoptosis.

Toxicology and applied pharmacology 20040801

Diosgenin induces apoptosis in HeLa cells via activation of caspase pathway.

Acta pharmacologica Sinica 20040801

Increased platelet phosphatidylserine exposure and caspase activation in chronic uremia.

Journal of thrombosis and haemostasis : JTH 20040801

Ca influx shutdown in neutrophils induced by Fas (CD95) cross-linking.

Immunology 20040701

Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells.

Oncogene 20040603

Norepinephrine induces apoptosis in neonatal rat cardiomyocytes through a reactive oxygen species-TNF alpha-caspase signaling pathway.

Cardiovascular research 20040601

Dieldrin promotes proteolytic cleavage of poly(ADP-ribose) polymerase and apoptosis in dopaminergic cells: protective effect of mitochondrial anti-apoptotic protein Bcl-2.

Neurotoxicology 20040601

Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing.

Genes to cells : devoted to molecular & cellular mechanisms 20040601

Differential contribution of necrosis and apoptosis in myocardial ischemia-reperfusion injury.

American journal of physiology. Heart and circulatory physiology 20040501

Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation.

International journal of molecular medicine 20040501

Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis.

Oncogene 20040401

The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.

Molecular cancer therapeutics 20040401

LIGHT sensitizes IFN-gamma-mediated apoptosis of HT-29 human carcinoma cells through both death receptor and mitochondria pathways.

Cell research 20040401

Caspase-3: its potential involvement in Cr(III)-induced apoptosis of lymphocytes.

Molecular and cellular biochemistry 20040401

Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase.

Biochemical and biophysical research communications 20040312

Diepoxybutane induces caspase and p53-mediated apoptosis in human lymphoblasts.

Toxicology and applied pharmacology 20040301

Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration.

Molecular and cellular neurosciences 20040301

Caspase-3 activation in systemic anaplastic large-cell lymphoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20040101

Norepinephrine induces apoptosis in neonatal rat endothelial cells via down-regulation of Bcl-2 and activation of beta-adrenergic and caspase-2 pathways.

Cardiovascular research 20040101

Inhibitors directed towards caspase-1 and -3 are less effective than pan caspase inhibition in preventing renal proximal tubular cell apoptosis.

Nephron. Experimental nephrology 20040101

Caspase 3-mediated proteolysis of the N-terminal cytoplasmic domain of the human erythroid anion exchanger 1 (band 3).

The Journal of biological chemistry 20031226

Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes.

The Journal of biological chemistry 20031205

15-Deoxy-delta12,14-prostaglandin J2, a ligand for peroxisome proliferators-activated receptor-gamma, induces apoptosis in human hepatoma cells.

Liver international : official journal of the International Association for the Study of the Liver 20031201

Apoptosis of lymphocytes induced by chromium(VI/V) is through ROS-mediated activation of Src-family kinases and caspase-3.

Free radical biology & medicine 20031101

Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis.

Cell death and differentiation 20031001

Caspase-3-dependent apoptosis in vascular smooth muscle cell by proteasome inhibition.

Journal of cardiovascular pharmacology 20031001

Apoptosis in human oral squamous cell carcinomas is induced by 15-deoxy-delta 12,14-prostaglandin J2 but not by troglitazone.

Journal of dental research 20031001

Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20031001

[Effects of caspases on cerebromicrovascular endothelial cell apoptosis induced by hypoxia].

Yao xue xue bao = Acta pharmaceutica Sinica 20031001

Caspase activity is essential for long-term potentiation.

Journal of neuroscience research 20030915

Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells.

Blood 20030801

Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity.

Cell death and differentiation 20030801

RU486-inducible retrovirus-mediated caspase-3 overexpression is cytotoxic to bcl-xL-expressing myeloma cells in vitro and in vivo.

Molecular therapy : the journal of the American Society of Gene Therapy 20030801

Activated monocytes induce human retinal pigment epithelial cell apoptosis through caspase-3 activation.

Laboratory investigation; a journal of technical methods and pathology 20030801

Anti-angiogenesis effects of borrelidin are mediated through distinct pathways: threonyl-tRNA synthetase and caspases are independently involved in suppression of proliferation and induction of apoptosis in endothelial cells.

The Journal of antibiotics 20030801

The p17 cleaved form of caspase-3 is present within viable macrophages in vitro and in atherosclerotic plaque.

Arteriosclerosis, thrombosis, and vascular biology 20030701

Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation.

Surgery 20030701

Triggering of apoptosis is not sufficient to induce human immunodeficiency virus gene expression.

IUBMB life 20030701

LIGHT sensitizes IFNgamma-mediated apoptosis of MDA-MB-231 breast cancer cells leading to down-regulation of anti-apoptosis Bcl-2 family members.

Cancer letters 20030610

Caspase 3 activation is essential for efficient influenza virus propagation.

The EMBO journal 20030602

Activation of a caspase-dependent oxidative damage response mediates TGFbeta1 apoptosis in rat hepatocytes.

Experimental and molecular pathology 20030601

The binding of protein S and the protein S-C4BP complex to neutrophils is apoptosis dependent.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030601

Calpain and caspase inhibitors protect vestibular sensory cells from gentamicin ototoxicity.

Acta oto-laryngologica 20030501

Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice.

Molecular vision 20030429

Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.

Oncogene 20030417

Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential.

Molecular carcinogenesis 20030401

Expression of Bcl-x(S) in Xenopus oocytes induces BH3-dependent and caspase-dependent cytochrome c release and apoptosis.

Molecular cancer research : MCR 20030101

Caspase inhibition does not protect against liver damage in hemorrhagic shock.

Shock (Augusta, Ga.) 20030101

Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells.

Cancer science 20030101

Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration.

Neuroscience 20030101

[Caspase-3 inhibition blocks long-term potentiation in hippocampal slices].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20030101

Implication of caspases during maedi-visna virus-induced apoptosis.

The Journal of general virology 20021201

Macrophage colony-stimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-X(L).

Experimental & molecular medicine 20021130

Enhancement of radiotherapy by oleandrin is a caspase-3 dependent process.

Cancer letters 20021128

Therapeutic effect of caspase inhibitors in the prevention of apoptosis and reversal of chronic cerebral vasospasm.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20021101

F-actin cleavage in apoptotic outer hair cells in chinchilla cochleas exposed to intense noise.

Hearing research 20021001

Induction of apoptosis dependent on caspase activities and growth arrest in HL-60 cells by PGA2.

Prostaglandins & other lipid mediators 20020901

Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes.

Journal of molecular and cellular cardiology 20020801

Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members.

The Journal of biological chemistry 20020726

Apoptosis is an adaptive response in bovine preimplantation embryos that facilitates survival after heat shock.

Biochemical and biophysical research communications 20020705

Different molecular events account for butyrate-induced apoptosis in two human colon cancer cell lines.

The Journal of nutrition 20020701

Manumycin inhibits farnesyltransferase and induces apoptosis of drug-resistant interleukin 6-producing myeloma cells.

British journal of haematology 20020701

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.

Oncogene 20020606

Preliminary study of the effects of caspase inhibitors on vasospasm in dog penetrating arteries.

Life sciences 20020510

Critical role of mitochondria, but not caspases, during glucocorticosteroid-induced human eosinophil apoptosis.

American journal of respiratory cell and molecular biology 20020501

Activation of caspase-like proteases and induction of apoptosis by isopentenyladenosine in tobacco BY-2 cells.

Planta 20020501

Morphine induces apoptosis of human microglia and neurons.

Neuropharmacology 20020501

Carbon monoxide protects pancreatic beta-cells from apoptosis and improves islet function/survival after transplantation.

Diabetes 20020401

Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells.

Acta pharmacologica Sinica 20020401

Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301

Caspase 3 regulates phosphatidylserine externalization and phagocytosis of oxidatively stressed erythrocytes.

FEBS letters 20020227

The 3C protease activity of enterovirus 71 induces human neural cell apoptosis.

Virology 20020215

p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells.

Neurobiology of disease 20020201

Thromboxane receptor signalling in human myometrial cells.

Prostaglandins & other lipid mediators 20020101

Induction of caspase-activated deoxyribonuclease activity after focal cerebral ischemia and reperfusion.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020101

Biochemical and morphological events during okadaic acid-induced apoptosis of Tsc2-null ERC-18 cell line.

Toxicologic pathology 20020101

Caspase-3-like proteases are activated by infection but are not required for replication of vesicular stomatitis virus.

Virus research 20011128

Involvement of caspases and of mitochondria in Fas ligation-induced eosinophil apoptosis: modulation by interleukin-5 and interferon-gamma.

Journal of leukocyte biology 20011101

Acetaminophen induces apoptosis of C6 glioma cells by activating the c-Jun NH(2)-terminal protein kinase-related cell death pathway.

Molecular pharmacology 20011001

Different orders for acquisition of apoptotic characteristics by leukocytes.

Journal of leukocyte biology 20010901

Enhancement of hyperthermia-induced apoptosis by a free radical initiator, 2,2'-azobis (2-amidinopropane) dihydrochloride, in human histiocytic lymphoma U937 cells.

Free radical research 20010901

Role of transcription factor Ets-1 in the apoptosis of human vascular endothelial cells.

Journal of cellular physiology 20010801

Neuroprotective signal transduction in model motor neurons exposed to thrombin: G-protein modulation effects on neurite outgrowth, Ca(2+) mobilization, and apoptosis.

Journal of neurobiology 20010801

Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis.

Journal of neuroscience research 20010701

Ethanol-induced apoptosis in mouse liver: Fas- and cytochrome c-mediated caspase-3 activation pathway.

The American journal of pathology 20010701

Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes.

Arthritis and rheumatism 20010701

Increased expression of the transcription factor E2F1 during dopamine-evoked, caspase-3-mediated apoptosis in rat cortical neurons.

Neuroscience letters 20010629

Caspase-3 inhibition partially protects oxidant production in apoptotic human neutrophils.

The Journal of surgical research 20010601

Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia.

British journal of pharmacology 20010601

Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells.

Leukemia 20010601

Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis.

Oncogene 20010524

Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry.

Cytometry 20010501

Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2.

Investigative ophthalmology & visual science 20010501

Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c From mitochondria in a rat forebrain ischemia model.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010501

The incidence of cytoplasmic fragmentation in mouse embryos in vitro is not affected by inhibition of caspase activity.

Fertility and sterility 20010501

Hypericin photo-induced apoptosis involves the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and activation of caspase-8.

FEBS letters 20010323

Caspase-mediated cleavage of TRAF3 in FasL-stimulated Jurkat-T cells.

Journal of leukocyte biology 20010301

Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells.

Journal of agricultural and food chemistry 20010301

Involvement of caspase-3 in apoptosis induced by Viscum album var. coloratum agglutinin in HL-60 cells.

Bioscience, biotechnology, and biochemistry 20010301

FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells.

Biochemical and biophysical research communications 20010223

Hamster Bcl-2 protein is cleaved in vitro and in cells by caspase-9 and caspase-3.

Biochemical and biophysical research communications 20010223

Proteolytic cleavage of epidermal growth factor receptor by caspases.

FEBS letters 20010223

Caspase inhibitors attenuate oxyhemoglobin-induced apoptosis in endothelial cells.

Stroke 20010201

Involvement of caspases in apoptotic cell death of murine macrophages infected with Actinobacillus actinomycetemcomitans.

Journal of periodontal research 20010201

Caspase-3 activity and carbonyl cyanide m-chlorophenylhydrazone-induced apoptosis in HL-60.

Alternatives to laboratory animals : ATLA 20010101

Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor.

Neuroscience 20010101

Caspase inhibition and N6-benzyladenosine-induced apoptosis in HL-60 cells.

Journal of cellular biochemistry 20010101

Induction of apoptosis in human leukemia cells by 3-deazaadenosine is mediated by caspase-3-like activity.

Experimental & molecular medicine 20001231

Degradation of the type I inositol 1,4,5-trisphosphate receptor by caspase-3 in SH-SY5Y neuroblastoma cells undergoing apoptosis.

Journal of neurochemistry 20001101

Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner in human gastric adenocarcinoma cells.

Cancer letters 20001001

The induction of cell death in human osteoarthritis chondrocytes by nitric oxide is related to the production of prostaglandin E2 via the induction of cyclooxygenase-2.

Journal of immunology (Baltimore, Md. : 1950) 20000915

Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis.

Journal of cell science 20000901

Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition.

The American journal of pathology 20000601

Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures.

Journal of neurochemistry 20000301

Caspase-3 mediated neuronal death after traumatic brain injury in rats.

Journal of neurochemistry 20000201

Rapid nucleolytic degradation of the small cytoplasmic Y RNAs during apoptosis.

The Journal of biological chemistry 19990827

Essential role of caspase-3 in apoptosis of mouse beta-cells transfected with human Fas.

Diabetes 19990301

Inhibition of caspases prevents cell death of hippocampal CA1 neurons, but not impairment of hippocampal long-term potentiation following global ischemia.

Neuroscience 19990101

Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis.

FEBS letters 19981127

Brefeldin A-mediated apoptosis requires the activation of caspases and is inhibited by Bcl-2.

Experimental cell research 19981125

Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.

The Journal of biological chemistry 19981023

Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 19981001

Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways.

The Journal of experimental medicine 19980907

Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.

The Journal of biological chemistry 19980814

Caspases (interleukin-1beta-converting enzyme family proteases) are involved in the regulation of the survival of osteoclasts.

Bone 19980701

Regulation of protein phosphatase 2A activity by caspase-3 during apoptosis.

The Journal of biological chemistry 19980522

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 19980301

p53-induced apoptosis in the human T-ALL cell line CCRF-CEM.

Oncogene 19971113

Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation.

Molecular and cellular biology 19971101