Z-IETD-FMK
Title | Journal |
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Molecular mechanism and inhibitory targets of dioscin in HepG2 cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20181001 |
Nickel ions from a corroded cardiovascular stent induce monocytic cell apoptosis: Proposed impact on vascular remodeling and mechanism. | Journal of the Formosan Medical Association = Taiwan yi zhi 20151101 |
Testosterone induces apoptosis in vascular smooth muscle cells via extrinsic apoptotic pathway with mitochondria-generated reactive oxygen species involvement. | American journal of physiology. Heart and circulatory physiology 20140601 |
Iso-suillin from the mushroom Suillus flavus induces cell cycle arrest and apoptosis in K562 cell line. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140501 |
Quercetin-3-O-(2'-galloyl)-α-l-rhamnopyranoside prevents TRAIL-induced apoptosis in human keratinocytes by suppressing the caspase-8- and Bid-pathways and the mitochondrial pathway. | Chemico-biological interactions 20130825 |
Newly synthesized quinazolinone HMJ-38 suppresses angiogenetic responses and triggers human umbilical vein endothelial cell apoptosis through p53-modulated Fas/death receptor signaling. | Toxicology and applied pharmacology 20130601 |
Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis. | Molecular biology reports 20121001 |
Multi-walled carbon nanotubes induce apoptosis via mitochondrial pathway and scavenger receptor. | Toxicology in vitro : an international journal published in association with BIBRA 20120901 |
Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis. | Oncology reports 20120601 |
5-Phenylselenyl- and 5-methylselenyl-methyl-2'-deoxyuridine induce oxidative stress, DNA damage, and caspase-2-dependent apoptosis in cancer cells. | Apoptosis : an international journal on programmed cell death 20120201 |
The apoptotic effects of the flavonoid N101-2 in human cervical cancer cells. | Toxicology in vitro : an international journal published in association with BIBRA 20120201 |
J7, a methyl jasmonate derivative, enhances TRAIL-mediated apoptosis through up-regulation of reactive oxygen species generation in human hepatoma HepG2 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20120201 |
Dehydrocorydaline inhibits breast cancer cells proliferation by inducing apoptosis in MCF-7 cells. | The American journal of Chinese medicine 20120101 |
Galangin induces apoptosis in hepatocellular carcinoma cells through the caspase 8/t-Bid mitochondrial pathway. | Journal of Asian natural products research 20120101 |
Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy. | Apoptosis : an international journal on programmed cell death 20111201 |
Okadaic acid induces apoptosis through the PKR, NF-κB and caspase pathway in human osteoblastic osteosarcoma MG63 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20111201 |
Characterization of Cholix toxin-induced apoptosis in HeLa cells. | The Journal of biological chemistry 20111028 |
Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL. | Carcinogenesis 20111001 |
Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells. | Apoptosis : an international journal on programmed cell death 20111001 |
Automatic morphological subtyping reveals new roles of caspases in mitochondrial dynamics. | PLoS computational biology 20111001 |
The extrinsic and intrinsic apoptotic pathways are involved in manganese toxicity in rat astrocytoma C6 cells. | Neurochemistry international 20110801 |
Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells. | Carcinogenesis 20110501 |
Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation. | Neuro-oncology 20110301 |
Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. | Apoptosis : an international journal on programmed cell death 20110201 |
3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model. | Molecular carcinogenesis 20110201 |
Combined treatment with the Cox-2 inhibitor niflumic acid and PPARγ ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells. | Cancer letters 20110128 |
Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways. | Chemical research in toxicology 20110114 |
Glucocorticoid-induced activation of caspase-8 protects the glucocorticoid-induced protein Gilz from proteasomal degradation and induces its binding to SUMO-1 in murine thymocytes. | Cell death and differentiation 20110101 |
Caspase activation is not required for villous cytotrophoblast fusion into syncytiotrophoblasts. | Placenta 20101101 |
1-(3',4',5'-Trimethoxyphenyl)-3-(3'',4''-dimethoxy-2''-hydroxyphenyl)-propane with microtubule-depolymerizing ability induces G2/M phase arrest and apoptosis in HepG2 cells. | Chemico-biological interactions 20101006 |
Isoangustone A present in hexane/ethanol extract of Glycyrrhiza uralensis induces apoptosis in DU145 human prostate cancer cells via the activation of DR4 and intrinsic apoptosis pathway. | Molecular nutrition & food research 20100901 |
Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells. | Nutrition and cancer 20100801 |
Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway. | Chemical research in toxicology 20100719 |
Caspases-2 and -8 are involved in the presenilin1/gamma-secretase-dependent cleavage of amyloid precursor protein after the induction of apoptosis. | Journal of neuroscience research 20100701 |
Para-phenylenediamine induced DNA damage and apoptosis through oxidative stress and enhanced caspase-8 and -9 activities in Mardin-Darby canine kidney cells. | Toxicology in vitro : an international journal published in association with BIBRA 20100601 |
Sulfur mustard induces apoptosis in lung epithelial cells via a caspase amplification loop. | Toxicology 20100527 |
The Ca(2+) channel blocker flunarizine induces caspase-10-dependent apoptosis in Jurkat T-leukemia cells. | Apoptosis : an international journal on programmed cell death 20100501 |
Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma. | International journal of cancer 20100401 |
Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells. | Autophagy 20100201 |
Role of endoplasmic reticulum stress in alpha-TEA mediated TRAIL/DR5 death receptor dependent apoptosis. | PloS one 20100101 |
Sulphasalazine accelerates apoptosis in neutrophils exposed to immune complex: Role of caspase pathway. | Clinical and experimental pharmacology & physiology 20091101 |
Recombinant YopJ induces apoptosis in murine peritoneal macrophages in vitro: involvement of mitochondrial death pathway. | International immunology 20091101 |
Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions. | Oncogene 20090910 |
Titanium dioxide nanoparticles induce apoptosis through the JNK/p38-caspase-8-Bid pathway in phytohemagglutinin-stimulated human lymphocytes. | Biochemical and biophysical research communications 20090904 |
The anti-apoptotic effects of caspase inhibitors on propyl gallate-treated HeLa cells in relation to reactive oxygen species and glutathione levels. | Archives of toxicology 20090901 |
Cyclic stretching force induces apoptosis in human periodontal ligament cells via caspase-9. | Archives of oral biology 20090901 |
N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells. | Toxicology and applied pharmacology 20090815 |
Mechanisms of resveratrol-induced platelet apoptosis. | Cardiovascular research 20090801 |
Involvement of both extrinsic and intrinsic apoptotic pathways in apoptosis induced by genistein in human cervical cancer cells. | Annals of the New York Academy of Sciences 20090801 |
Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells. | Chemico-biological interactions 20090715 |
Nimesulide, a selective COX-2 inhibitor, acts synergistically with ionizing radiation against A549 human lung cancer cells through the activation of caspase-8 and caspase-3. | International journal of oncology 20090501 |
Caspase-8 is involved in neovascularization-promoting progenitor cell functions. | Arteriosclerosis, thrombosis, and vascular biology 20090401 |
Multiple signal transduction pathways in okadaic acid induced apoptosis in HeLa cells. | Toxicology 20090204 |
Caspase-dependent molecular mechanisms of anti-human DR5 monoclonal antibody mDRA-6 inducing apoptosis of human leukemia Jurkat cells. | Ai zheng = Aizheng = Chinese journal of cancer 20090201 |
Selective induction of apoptosis of human oral cancer cell lines by avocado extracts via a ROS-mediated mechanism. | Nutrition and cancer 20090101 |
Protein tyrosine kinase p56lck-deficiency confers hypersusceptibility to rho-fluorophenylalanine (pFPhe)-induced apoptosis by augmenting mitochondrial apoptotic pathway in human Jurkat T cells. | Biochemical and biophysical research communications 20081205 |
Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavage. | Molecular cancer therapeutics 20080601 |
The characteristic of an anti-human DR5 antibody A6. | Cellular & molecular immunology 20080601 |
Galectin-1 induced activation of the apoptotic death-receptor pathway in human Jurkat T lymphocytes. | Histochemistry and cell biology 20080501 |
Bid is not required for Bax translocation during UV-induced apoptosis. | Cellular signalling 20071201 |
Synapse-specific plasticity in command neurons during learning of edible snails under the action of caspase inhibitors. | Bulletin of experimental biology and medicine 20071201 |
Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways. | Biochimica et biophysica acta 20071101 |
Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun activation. | Molecules and cells 20070831 |
Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells. | Toxicology and applied pharmacology 20070715 |
TNFalpha induces apoptosis through JNK/Bax-dependent pathway in differentiated, but not naïve PC12 cells. | Cell cycle (Georgetown, Tex.) 20070615 |
Activation of the death receptor pathway of apoptosis by the aldehyde acrolein. | Free radical biology & medicine 20070315 |
Sulfasalazine unveils a contact-independent HSV-TK/ganciclovir gene therapy bystander effect in malignant gliomas. | International journal of oncology 20070101 |
Activation of caspase-8 triggers anoikis in human neuroblastoma cells. | Neuroscience research 20061001 |
Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling. | Oncogene 20060914 |
Re-evaluation of the distinction between type I and type II cells: the necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon Fas receptor activation. | Journal of cellular physiology 20060901 |
Inhibition of caspase-8 attenuates neuronal death induced by limbic seizures in a cytochrome c-dependent and Smac/DIABLO-independent way. | Brain research 20060707 |
Cadmium-induced apoptosis in murine macrophages is antagonized by antioxidants and caspase inhibitors. | Journal of toxicology and environmental health. Part A 20060601 |
Interaction between endoplasmic reticulum stress and caspase 8 activation in retrovirus MoMuLV-ts1-infected astrocytes. | Virology 20060510 |
Cadmium inhibits both intrinsic and extrinsic apoptotic pathways in renal mesangial cells. | American journal of physiology. Renal physiology 20060501 |
Prostate-apoptosis-response-gene-4 increases sensitivity to TRAIL-induced apoptosis. | Leukemia research 20060501 |
E-cadherin and its downstream catenins are proteolytically cleaved in human HaCaT keratinocytes exposed to UVB. | Experimental dermatology 20060401 |
Caspase-8 activation and oxidative stress are involved in the cytotoxic effect of beta-amyloid on rat brain microvascular endothelial cells. | International journal of molecular medicine 20060301 |
Adenovirus E1A reverses the resistance of normal primary human lung fibroblast cells to TRAIL through DR5 upregulation and caspase 8-dependent pathway. | Cancer biology & therapy 20060201 |
Apo2L/TRAIL is an indirect mediator of apoptosis induced by interferon-alpha in human myeloma cells. | FEBS letters 20051107 |
Synergistic apoptosis induction by proteasome and histone deacetylase inhibitors is dependent on protein synthesis. | Apoptosis : an international journal on programmed cell death 20050801 |
Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium. | The Biochemical journal 20050715 |
Tumor necrosis factor-{alpha} decreases Akt protein levels in 3T3-L1 adipocytes via the caspase-dependent ubiquitination of Akt. | Endocrinology 20050601 |
Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines. | Molecular cancer therapeutics 20050401 |
Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells. | Molecular cancer therapeutics 20050301 |
CD95 apoptosis resistance in certain cells can be overcome by noncanonical activation of caspase-8. | Cell death and differentiation 20050101 |
Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells. | British journal of cancer 20041101 |
FLIP overexpression inhibits death receptor-induced apoptosis in malignant mesothelial cells. | Oncogene 20041014 |
Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism. | Carcinogenesis 20041001 |
Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways. | Cell death and differentiation 20040901 |
6-Hydroxydopamine induces dopaminergic cell degeneration via a caspase-9-mediated apoptotic pathway that is attenuated by caspase-9dn expression. | Journal of neuroscience research 20040901 |
Role of glutathione in dimethylarsinic acid-induced apoptosis. | Toxicology and applied pharmacology 20040801 |
Ca influx shutdown in neutrophils induced by Fas (CD95) cross-linking. | Immunology 20040701 |
Norepinephrine induces apoptosis in neonatal rat cardiomyocytes through a reactive oxygen species-TNF alpha-caspase signaling pathway. | Cardiovascular research 20040601 |
Differential contribution of necrosis and apoptosis in myocardial ischemia-reperfusion injury. | American journal of physiology. Heart and circulatory physiology 20040501 |
Caspase inhibitors attenuate superantigen-induced inflammatory cytokines, chemokines, and T-cell proliferation. | Clinical and diagnostic laboratory immunology 20040501 |
Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase. | Biochemical and biophysical research communications 20040312 |
Chemical sensitization and regulation of TRAIL-induced apoptosis in a panel of B-lymphocytic leukaemia cell lines. | British journal of haematology 20031201 |
Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells. | The Journal of biological chemistry 20031017 |
Influenza A virus-induced apoptosis in bronchiolar epithelial (NCI-H292) cells limits pro-inflammatory cytokine release. | The Journal of general virology 20030901 |
Kahalalide F, a new marine-derived compound, induces oncosis in human prostate and breast cancer cells. | Molecular cancer therapeutics 20030901 |
Anti-angiogenesis effects of borrelidin are mediated through distinct pathways: threonyl-tRNA synthetase and caspases are independently involved in suppression of proliferation and induction of apoptosis in endothelial cells. | The Journal of antibiotics 20030801 |
Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways. | Toxicology and applied pharmacology 20030701 |
New benzo(b)thiophenesulphonamide 1,1-dioxide derivatives induce a reactive oxygen species-mediated process of apoptosis in tumour cells. | Oncogene 20030612 |
Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop. | Oncogene 20030417 |
Galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway. | Journal of immunology (Baltimore, Md. : 1950) 20030401 |
Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341. | Blood 20030215 |
Study of caspase inhibitors for limiting death in mammalian cell culture. | Biotechnology and bioengineering 20030205 |
Neutralization of TRAIL death pathway protects human neuronal cell line from beta-amyloid toxicity. | Cell death and differentiation 20030101 |
Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway. | Cell death and differentiation 20020901 |
DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way. | Oncogene 20020829 |
Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells. | Acta pharmacologica Sinica 20020401 |
Acid sphingomyelinase activation requires caspase-8 but not p53 nor reactive oxygen species during Fas-induced apoptosis in human glioma cells. | Experimental cell research 20020215 |
Involvement of caspases and of mitochondria in Fas ligation-induced eosinophil apoptosis: modulation by interleukin-5 and interferon-gamma. | Journal of leukocyte biology 20011101 |
Differential involvement of initiator caspases in apoptotic volume decrease and potassium efflux during Fas- and UV-induced cell death. | The Journal of biological chemistry 20011005 |
Cleavage of bid may amplify caspase-8-induced neuronal death following focally evoked limbic seizures. | Neurobiology of disease 20010801 |
beta-amyloid induces caspase-dependent early neurotoxic change in PC12 cells: correlation with H2O2 neurotoxicity. | Neuroscience letters 20010601 |
Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells. | Leukemia 20010601 |
Oxyhemoglobin induces caspase-mediated cell death in cerebral endothelial cells. | Journal of neurochemistry 20010501 |
Hypericin photo-induced apoptosis involves the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and activation of caspase-8. | FEBS letters 20010323 |
Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis. | Cancer research 20010201 |
Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels. | Cancer research 20010115 |
Apoptosis induced by cadmium in human lymphoma U937 cells through Ca2+-calpain and caspase-mitochondria- dependent pathways. | The Journal of biological chemistry 20001215 |
Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro. | Biochemical pharmacology 20000715 |
Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition. | The American journal of pathology 20000601 |
Rapid nucleolytic degradation of the small cytoplasmic Y RNAs during apoptosis. | The Journal of biological chemistry 19990827 |