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Fodosine

CAS No.:
209799-67-7
Catalog Number:
AG002KEW
Molecular Formula:
C11H14N4O4
Molecular Weight:
266.2533
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
95%
1 week
United States
$882
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Product Description
Catalog Number:
AG002KEW
Chemical Name:
Fodosine
CAS Number:
209799-67-7
Molecular Formula:
C11H14N4O4
Molecular Weight:
266.2533
MDL Number:
MFCD09837827
IUPAC Name:
7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one
InChI:
InChI=1S/C11H14N4O4/c16-2-5-9(17)10(18)7(15-5)4-1-12-8-6(4)13-3-14-11(8)19/h1,3,5,7,9-10,12,15-18H,2H2,(H,13,14,19)/t5-,7+,9-,10+/m1/s1
InChI Key:
IWKXDMQDITUYRK-KUBHLMPHSA-N
SMILES:
OC[C@H]1N[C@H]([C@@H]([C@@H]1O)O)c1c[nH]c2c1nc[nH]c2=O
UNII:
426X066ELK
Properties
Complexity:
404  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
266.102g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0
Molecular Weight:
266.257g/mol
Monoisotopic Mass:
266.102g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
130A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.3  
Literature
Title Journal
Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases. Organic & biomolecular chemistry 20060321
The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase works as an arsenate reductase in human red blood cells and rat liver cytosol. Toxicological sciences : an official journal of the Society of Toxicology 20050601
Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase. Toxicological sciences : an official journal of the Society of Toxicology 20030701
Purine nucleoside phosphorylase as a cytosolic arsenate reductase. Toxicological sciences : an official journal of the Society of Toxicology 20021101
Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America 20010410
One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase. Biochemistry 19980616
Properties