Home Other Building Blocks Isobavachalcone

Isobavachalcone

CAS No.:
20784-50-3
Catalog Number:
AG002JB9
Molecular Formula:
C20H20O4
Molecular Weight:
324.3704
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥98%
1 week
United States
$139
- +
10mg
≥98%
1 week
United States
$212
- +
25mg
≥98%
1 week
United States
$426
- +
50mg
≥98%
1 week
United States
$712
- +
Product Description
Catalog Number:
AG002JB9
Chemical Name:
Isobavachalcone
CAS Number:
20784-50-3
Molecular Formula:
C20H20O4
Molecular Weight:
324.3704
MDL Number:
MFCD00902090
IUPAC Name:
(E)-1-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
InChI:
InChI=1S/C20H20O4/c1-13(2)3-9-16-19(23)12-10-17(20(16)24)18(22)11-6-14-4-7-15(21)8-5-14/h3-8,10-12,21,23-24H,9H2,1-2H3/b11-6+
InChI Key:
DUWPGRAKHMEPCM-IZZDOVSWSA-N
SMILES:
CC(=CCc1c(O)ccc(c1O)C(=O)/C=C/c1ccc(cc1)O)C
Properties
Complexity:
470  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
324.136g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
324.376g/mol
Monoisotopic Mass:
324.136g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
77.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.1  
Literature
Title Journal
Separation of isomeric bavachin and isobavachalcone in the fructus Psoraleae by capillary electrophoresis-mass spectrometry. Journal of separation science 20120701
Isobavachalcone: an overview. Chinese journal of integrative medicine 20120701
Antibacterial activity of chalcones, hydrazones and oxadiazoles against methicillin-resistant Staphylococcus aureus. Bioorganic & medicinal chemistry letters 20120101
Determination of bavachin and isobavachalcone in Fructus Psoraleae by high-performance liquid chromatography with electrochemical detection. Journal of separation science 20110301
Evaluation of flavonoids from Dorstenia barteri for their antimycobacterial, antigonorrheal and anti-reverse transcriptase activities. Acta tropica 20101001
Abrogation of Akt signaling by Isobavachalcone contributes to its anti-proliferative effects towards human cancer cells. Cancer letters 20100828
Total synthesis, antiprotozoal and cytotoxicity activities of rhuschalcone VI and analogs. Bioorganic & medicinal chemistry 20100401
Inhibitory effects of bakuchiol, bavachin, and isobavachalcone isolated from Piper longum on melanin production in B16 mouse melanoma cells. Bioscience, biotechnology, and biochemistry 20100101
[Flavonoids from the leaves of Morus alba L]. Yao xue xue bao = Acta pharmaceutica Sinica 20100101
Bavachin and isobavachalcone, acyl-coenzyme A: cholesterol acyltransferase inhibitors from Psoralea corylifolia. Archives of pharmacal research 20081101
Naturally occurring homoisoflavonoids function as potent protein tyrosine kinase inhibitors by c-Src-based high-throughput screening. Journal of medicinal chemistry 20080814
Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma. Biological & pharmaceutical bulletin 20071001
Chemical fingerprint and quantitative analysis of fructus psoraleae by high-performance liquid chromatography. Journal of separation science 20070401
Compounds with DNA cleaving activity from Kadsura ananosma. Die Pharmazie 20061001
Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production. Journal of natural products 20060401
Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects. Journal of natural products 20060101
Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects. Cancer letters 20031125
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies. Journal of natural products 20021201
Antioxidative components of Psoralea corylifolia (Leguminosae). Phytotherapy research : PTR 20020901
Aromatase inhibitors from Broussonetia papyrifera. Journal of natural products 20011001
Antifungal chalcones from Maclura tinctoria. Planta medica 20010201
Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines. Anticancer research 20000101
Properties