Home Aminos Benzenemethanol, 3-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-

Benzenemethanol, 3-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-

CAS No.:
207679-81-0
Catalog Number:
AG002J79
Molecular Formula:
C22H31NO2
Molecular Weight:
341.4870
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$372
- +
10mg
99%
1 week
United States
$605
- +
50mg
99%
1 week
United States
$1305
- +
100mg
99%
1 week
United States
$2123
- +
Product Description
Catalog Number:
AG002J79
Chemical Name:
Benzenemethanol, 3-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-
CAS Number:
207679-81-0
Molecular Formula:
C22H31NO2
Molecular Weight:
341.4870
MDL Number:
MFCD09264524
IUPAC Name:
2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenol
InChI:
InChI=1S/C22H31NO2/c1-16(2)23(17(3)4)13-12-20(19-8-6-5-7-9-19)21-14-18(15-24)10-11-22(21)25/h5-11,14,16-17,20,24-25H,12-13,15H2,1-4H3/t20-/m1/s1
InChI Key:
DUXZAXCGJSBGDW-HXUWFJFHSA-N
SMILES:
OCc1ccc(c(c1)[C@@H](c1ccccc1)CCN(C(C)C)C(C)C)O
UNII:
YU871O78GR
Properties
Complexity:
357  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
341.235g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
341.495g/mol
Monoisotopic Mass:
341.235g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
43.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.4  
Literature
Title Journal
Comparison of pharmacokinetic variability of fesoterodine vs. tolterodine extended release in cytochrome P450 2D6 extensive and poor metabolizers. British journal of clinical pharmacology 20110801
Pharmacokinetics of tolterodine in Japanese and Koreans: physiological and stochastic assessment of ethnic differences. Drug metabolism and pharmacokinetics 20110601
Effects of hepatic dysfunction on the single-dose pharmacokinetics of fesoterodine. Journal of clinical pharmacology 20110301
Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction. The Journal of urology 20100801
The pharmacokinetic profile of fesoterodine 8 mg with daytime or nighttime dosing. European journal of clinical pharmacology 20100201
The design and development of fesoterodine as a prodrug of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of tolterodine. Current medicinal chemistry 20090101
Pharmacokinetic profile of fesoterodine. International journal of clinical pharmacology and therapeutics 20081101
Effect of the proton pump inhibitor omeprazole on the pharmacokinetics of extended-release formulations of oxybutynin and tolterodine. Journal of clinical pharmacology 20050801
Tolterodine and its active 5-hydroxymethyl metabolite: pure muscarinic receptor antagonists. Pharmacology & toxicology 20020501
The effect of tolterodine on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive containing ethinyl estradiol and levonorgestrel. Clinical therapeutics 20011101
Food increases the bioavailability of tolterodine but not effective exposure. Journal of clinical pharmacology 20010301
Properties