2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-
| Title | Journal |
|---|---|
| Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction. | The Journal of biological chemistry 20121005 |
| Profiling cytosine oxidation in DNA by LC-MS/MS. | Chemical research in toxicology 20120917 |
| Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities. | DNA repair 20120901 |
| A DNA oligomer containing 2,2,4-triamino-5(2H)-oxazolone is incised by human NEIL1 and NTH1. | Mutation research 20120601 |
| Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA. | The Journal of biological chemistry 20120203 |
| DNA glycosylases: in DNA repair and beyond. | Chromosoma 20120201 |
| Association of polymorphisms in oxidative stress genes with clinical outcomes for bladder cancer treated with Bacillus Calmette-Guérin. | PloS one 20120101 |
| A nano-chip-LC/MSn based strategy for characterization of modified nucleosides using reduced porous graphitic carbon as a stationary phase. | Journal of the American Society for Mass Spectrometry 20110701 |
| Delayed repair of radiation induced clustered DNA damage: friend or foe? | Mutation research 20110603 |
| Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability. | PLoS genetics 20110601 |
| Preferential repair of oxidized base damage in the transcribed genes of mammalian cells. | The Journal of biological chemistry 20110225 |
| New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. | PloS one 20110101 |
| Direct detection and sequencing of damaged DNA bases. | Genome integrity 20110101 |
| Base-promoted reaction of 5-hydroxyuracil derivatives with peroxyl radicals. | Organic letters 20100917 |
| Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases. | The Journal of biological chemistry 20100910 |
| Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100701 |
| RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures. | DNA repair 20100604 |
| Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases. | DNA repair 20100604 |
| The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts. | DNA repair 20100204 |
| Stimulation of DNA Glycosylase Activities by XPC Protein Complex: Roles of Protein-Protein Interactions. | Journal of nucleic acids 20100101 |
| Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe. | Journal of nucleic acids 20100101 |
| Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair. | Journal of nucleic acids 20100101 |
| Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine. | Journal of clinical biochemistry and nutrition 20091101 |
| Modulation of DNA glycosylase activities in mesenchymal stem cells. | Experimental cell research 20090910 |
| Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma. | Carcinogenesis 20090701 |
| Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats. | FEMS immunology and medical microbiology 20090701 |
| The Base Excision Repair system of Salmonella enterica serovar typhimurium counteracts DNA damage by host nitric oxide. | PLoS pathogens 20090501 |
| Base excision repair of oxidative DNA damage and association with cancer and aging. | Carcinogenesis 20090101 |
| Raltegravir, elvitegravir, and metoogravir: the birth of 'me-too' HIV-1 integrase inhibitors. | Retrovirology 20090101 |
| Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity. | BMC biochemistry 20090101 |
| Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1. | The Journal of biological chemistry 20081003 |
| Base excision repair activities in organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation. | DNA repair 20080601 |
| Examination of hypochlorous acid-induced damage to cytosine residues in a CpG dinucleotide in DNA. | Chemical research in toxicology 20080601 |
| Base-pairing properties of the oxidized cytosine derivative, 5-hydroxy uracil. | Biochemical and biophysical research communications 20080215 |
| Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes. | The Journal of biological chemistry 20080208 |
| Ab initio base-pairing energies of an oxidized thymine product, 5-formyluracil, with standard DNA bases at the BSSE-free DFT and MP2 theory levels. | Organic & biomolecular chemistry 20070521 |
| Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress. | Neuroscience 20070414 |
| NEIL1 is the major DNA glycosylase that processes 5-hydroxyuracil in the proximity of a DNA single-strand break. | Biochemistry 20070403 |
| Uracil in DNA--general mutagen, but normal intermediate in acquired immunity. | DNA repair 20070401 |
| Radiosensitization by nitric oxide at low radiation doses. | Radiation research 20070401 |
| DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions. | Nucleic acids research 20070201 |
| Base excision repair and the role of MUTYH. | Hereditary cancer in clinical practice 20070101 |
| NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. | DNA repair 20061209 |
| RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors. | The EMBO journal 20061129 |
| Ab initio base-pairing energies of uracil and 5-hydroxyuracil with standard DNA bases at the BSSE-free DFT and MP2 theory levels. | Organic & biomolecular chemistry 20060507 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Physical and functional interactions between Escherichia coli MutY and endonuclease VIII. | The Biochemical journal 20060101 |
| Differential modulation of base excision repair activities during brain ontogeny: implications for repair of transcribed DNA. | Mechanisms of ageing and development 20060101 |
| DNA oxidation in Alzheimer's disease. | Antioxidants & redox signaling 20060101 |
| Reaction of substituted pyrimidines with photochemically generated t-BuO* radicals. | Indian journal of biochemistry & biophysics 20051201 |
| 5-hydroxyuracil can form stable base pairs with all four bases in a DNA duplex. | Chemical communications (Cambridge, England) 20050121 |
| Identification of a zinc finger domain in the human NEIL2 (Nei-like-2) protein. | The Journal of biological chemistry 20041105 |
| Oxidation of 5-hydroxy-2'-deoxyuridine into isodialuric acid, dialuric acid, and hydantoin products. | Journal of the American Chemical Society 20040602 |
| Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2. | The Journal of biological chemistry 20031212 |
| Detection of p53 mutations in precancerous gastric tissue. | British journal of cancer 20031006 |
| Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases. | The Journal of biological chemistry 20030905 |
| Mammalian 5-formyluracil-DNA glycosylase. 1. Identification and characterization of a novel activity that releases 5-formyluracil from DNA. | Biochemistry 20030506 |
| Oxidative DNA base modifications and polycyclic aromatic hydrocarbon DNA adducts in squamous cell carcinoma of larynx. | Free radical research 20030301 |
| Identification and characterization of mammalian 5-formyluracil-DNA glycosylase. | Nucleic acids research. Supplement (2001) 20030101 |
| A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue. | The Journal of biological chemistry 20021101 |
| Repair of deaminated bases in DNA. | Free radical biology & medicine 20021001 |
| Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions. | The Journal of biological chemistry 20020823 |
| Biological consequences of free radical-damaged DNA bases. | Free radical biology & medicine 20020701 |
| Determination of active site residues in Escherichia coli endonuclease VIII. | The Journal of biological chemistry 20020125 |
| Alternative nucleotide incision repair pathway for oxidative DNA damage. | Nature 20020110 |
| Stimulation of human endonuclease III by Y box-binding protein 1 (DNA-binding protein B). Interaction between a base excision repair enzyme and a transcription factor. | The Journal of biological chemistry 20010615 |
| Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii. | Biochemical pharmacology 19940817 |
| New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase. | The Journal of biological chemistry 19940722 |