Home Halogens 1H-Pyrazole-3-carboxamide, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-

1H-Pyrazole-3-carboxamide, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-

CAS No.:
192703-06-3
Catalog Number:
AG002G8I
Molecular Formula:
C29H34ClN3O
Molecular Weight:
476.0528
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥98%
1 week
United States
$189
- +
10mg
≥98%
1 week
United States
$308
- +
25mg
≥98%
1 week
United States
$651
- +
50mg
99%
1 week
United States
$1090
- +
100mg
99%
1 week
United States
$1890
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Product Description
Catalog Number:
AG002G8I
Chemical Name:
1H-Pyrazole-3-carboxamide, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-
CAS Number:
192703-06-3
Molecular Formula:
C29H34ClN3O
Molecular Weight:
476.0528
MDL Number:
MFCD05662316
IUPAC Name:
5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]pyrazole-3-carboxamide
InChI:
InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1
InChI Key:
SUGVYNSRNKFXQM-XRHWURSXSA-N
SMILES:
Cc1ccc(cc1)Cn1nc(cc1c1ccc(c(c1)C)Cl)C(=O)N[C@H]1[C@@]2(C)CC[C@@H](C1(C)C)C2
Properties
Complexity:
750  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
475.239g/mol
Formal Charge:
0
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
476.061g/mol
Monoisotopic Mass:
475.239g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
46.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
7.4  
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Modulation of cytokine responses in Corynebacterium parvum-primed endotoxemic mice by centrally administered cannabinoid ligands. European journal of pharmacology 20010803
Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor. Cancer research 20010801
Cannabinoid activation of recombinant and endogenous vanilloid receptors. European journal of pharmacology 20010727
Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. European journal of pharmacology 20010511
Cannabinoid inhibition of capsaicin-sensitive sensory neurotransmission in the rat mesenteric arterial bed. European journal of pharmacology 20010420
Inhibitory effects of SR141716A on G-protein activation in rat brain. European journal of pharmacology 20010302
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Cannabinoids and pain. Current opinion in investigational drugs (London, England : 2000) 20010301
In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for cannabinoid CB2 receptor. The Journal of pharmacology and experimental therapeutics 20010201
Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. European journal of biochemistry 20010201
Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide. British journal of pharmacology 20010201
Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats. Naunyn-Schmiedeberg's archives of pharmacology 20010201
Delta-9-tetrahydrocannabinol differentially suppresses cisplatin-induced emesis and indices of motor function via cannabinoid CB(1) receptors in the least shrew. Pharmacology, biochemistry, and behavior 20010101
Genomic and functional changes induced by the activation of the peripheral cannabinoid receptor CB2 in the promyelocytic cells HL-60. Possible involvement of the CB2 receptor in cell differentiation. The Journal of biological chemistry 20000526
Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor. The Journal of pharmacology and experimental therapeutics 20000301
Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. The Journal of biological chemistry 20000107
HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor. Proceedings of the National Academy of Sciences of the United States of America 19991207
Stimulation of peripheral cannabinoid receptor CB2 induces MCP-1 and IL-8 gene expression in human promyelocytic cell line HL60. FEBS letters 19990409
Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656, and AM630. British journal of pharmacology 19990201
SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor. The Journal of pharmacology and experimental therapeutics 19980201
Properties