Urea, N-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-
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The synthetic inhibitor of fibroblast growth factor receptor PD166866 controls negatively the growth of tumor cells in culture. | Journal of experimental & clinical cancer research : CR 20090101 |
2D Autocorrelation, CoMFA, and CoMSIA modeling of protein tyrosine kinases' inhibition by substituted pyrido[2,3-d]pyrimidine derivatives. | Bioorganic & medicinal chemistry 20080115 |
Reduction of cell proliferation induced by PD166866: an inhibitor of the basic fibroblast growth factor. | Journal of experimental & clinical cancer research : CR 20070901 |
Metabolic alterations in cultured mouse fibroblasts induced by an inhibitor of the tyrosine kinase receptor Fibroblast Growth Factor Receptor 1. | Analytical biochemistry 20070801 |
Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis. | Journal of neurochemistry 20060501 |
Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis. | Journal of neurochemistry 20050401 |
Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1. | Bioorganic & medicinal chemistry letters 20050401 |
Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050401 |
Essential role of fibroblast growth factor signaling in preadipoctye differentiation. | The Journal of clinical endocrinology and metabolism 20050201 |
Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells. | Journal of applied physiology (Bethesda, Md. : 1985) 20041001 |
Thyroid hormone activates fibroblast growth factor receptor-1 in bone. | Molecular endocrinology (Baltimore, Md.) 20030901 |
Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity. | Journal of medicinal chemistry 20010607 |
Development of a binding model to protein tyrosine kinases for substituted pyrido[2,3-d]pyrimidine inhibitors. | Journal of medicinal chemistry 19980521 |