Transport characteristics of clarithromycin, azithromycin and telithromycin, antibiotics applied for treatment of respiratory infections, in Calu-3 cell monolayers as model lung epithelial cells.

Die Pharmazie 20120501

Predicting drug interaction potential with a physiologically based pharmacokinetic model: a case study of telithromycin, a time-dependent CYP3A inhibitor.

Clinical pharmacology and therapeutics 20120401

Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens.

Bioorganic & medicinal chemistry letters 20120101

Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation.

Journal of clinical pharmacology 20120101

Understanding the regulatory hurdles for antibacterial drug development in the post-Ketek world.

Annals of the New York Academy of Sciences 20111201

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

PLoS computational biology 20111201

Alterations in regulatory regions of erm(B) genes from clinical isolates of enterococci resistant to telithromycin.

Archives of pharmacal research 20111201

Anti-inflammatory effects of garenoxacin on IL-8 production and ERK1/2 activation induced by lipopolysaccharides in A549 and THP-1 cells.

European journal of pharmacology 20111001

Total synthesis of (-)-4,8,10-tridesmethyl telithromycin.

The Journal of organic chemistry 20110916

Clarithromycin and telithromycin increases interleukin-10 expression in the rat endometriosis model.

Cytokine 20110901

Synthesis, activity and pharmacokinetics of novel antibacterial 15-membered ring macrolones.

European journal of medicinal chemistry 20110801

[Influence of a regulatory safety warning on the use of telithromycin].

Medicina clinica 20110416

Synthesis and antibacterial activity of novel ketolides with 11,12-sulfur contained aryl alkyl side chains.

European journal of medicinal chemistry 20110101

Differences in clinical features according to Boryoung and Karp genotypes of Orientia tsutsugamushi.

PloS one 20110101

Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials.

Bioorganic & medicinal chemistry 20101215

Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

Toxicological sciences : an official journal of the Society of Toxicology 20101201

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug metabolism and disposition: the biological fate of chemicals 20101201

Degradation kinetics of telithromycin determined by HPLC method.

Journal of chromatographic science 20101101

4''-O-(omega-Quinolylamino-alkylamino)propionyl derivatives of selected macrolides with the activity against the key erythromycin resistant respiratory pathogens.

Bioorganic & medicinal chemistry 20100901

6-Alkylquinolone-3-carboxylic acid tethered to macrolides synthesis and antimicrobial profile.

Bioorganic & medicinal chemistry 20100901

Synthesis and properties of macrolones characterized by two ether bonds in the linker.

Bioorganic & medicinal chemistry 20100901

Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides.

Journal of medicinal chemistry 20100812

Detection of a new erm(X)-mediated antibiotic resistance in Egyptian cutaneous propionibacteria.

Anaerobe 20100801

Disposition of oral telithromycin in foals and in vitro activity of the drug against macrolide-susceptible and macrolide-resistant Rhodococcus equi isolates.

Journal of veterinary pharmacology and therapeutics 20100801

Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections.

Drug development and industrial pharmacy 20100701

Mutational analysis of reduced telithromycin susceptibility of Streptococcus pneumoniae isolated clinically in Japan.

FEMS microbiology letters 20100601

Novel 8a-aza-8a-homoerythromycin--4''-(3-substituted-amino)propionates with broad spectrum antibacterial activity.

Bioorganic & medicinal chemistry letters 20100601

Neuropsychological effects of macrolides.

Prescrire international 20100601

Telithromycin blocks neuromuscular transmission and inhibits nAChR currents in vitro.

Toxicology letters 20100504

Novel azalides derived from 16-membered macrolides. III. Azalides modified at the C-15 and 4'' positions: Improved antibacterial activities.

Bioorganic & medicinal chemistry 20100401

[Investigation of macrolide-lincosamide-streptogramin B (MLS(B)) and telithromycin resistance in clinical strains of staphylococci].

Mikrobiyoloji bulteni 20100401

Telithromycin: visual disorders.

Prescrire international 20100401

Pharmacokinetic interaction between telithromycin and metformin in diabetes mellitus rats.

Xenobiotica; the fate of foreign compounds in biological systems 20100301

Effect of telithromycin on the pharmacokinetics and pharmacodynamics of oral oxycodone.

Journal of clinical pharmacology 20100101

In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms.

Antimicrobial agents and chemotherapy 20100101

Recent advances in the medicinal chemistry of novel erythromycin-derivatized antibiotics.

Current topics in medicinal chemistry 20100101

Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages.

The Journal of pharmacy and pharmacology 20100101

Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.

Journal of medicinal chemistry 20091210

Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells.

Pulmonary pharmacology & therapeutics 20091201

Macrolides, ketolides, and glycylcyclines: azithromycin, clarithromycin, telithromycin, tigecycline.

Infectious disease clinics of North America 20091201

Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activity.

Bioorganic & medicinal chemistry letters 20090801

Pharmacodynamic target attainment potential of azithromycin, clarithromycin, and telithromycin in serum and epithelial lining fluid of community-acquired pneumonia patients with penicillin-susceptible, intermediate, and resistant Streptococcus pneumoniae.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20090701

Multiple-dose pharmacokinetics of telithromycin in peripheral soft tissues.

International journal of antimicrobial agents 20090701

Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.

Toxicology and applied pharmacology 20090615

New antimicrobial molecules and new antibiotic strategies.

Seminars in respiratory and critical care medicine 20090401

Antibacterial activity of telithromycin and comparators against pathogens isolated from patients with community-acquired respiratory tract infections: the Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin study year 5 (2003-2004).

Diagnostic microbiology and infectious disease 20090301

LC method for telithromycin in tablets: a stability-indicating assay.

International journal of pharmaceutics 20090121

Different effects of telithromycin on MUC5AC production induced by human neutrophil peptide-1 or lipopolysaccharide in NCI-H292 cells compared with azithromycin and clarithromycin.

The Journal of antimicrobial chemotherapy 20090101

Telithromycin-associated hepatotoxicity: Clinical spectrum and causality assessment of 42 cases.

Hepatology (Baltimore, Md.) 20090101

Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages.

Drug metabolism and pharmacokinetics 20090101

[Pneumonia in a traveller coming back from Asia].

Medecine et maladies infectieuses 20081201

Time-dependent effects of Klebsiella pneumoniae endotoxin on the telithromycin pharmacokinetics in rats; restoration of the parameters in 96-hour KPLPS rats to the control levels.

Pulmonary pharmacology & therapeutics 20081201

Risk of hepatotoxicity associated with the use of telithromycin: a signal detection using data mining algorithms.

The Annals of pharmacotherapy 20081201

A ketolide antibiotic, telithromycin, inhibits vascular adrenergic neurotransmission in the rat mesenteric vascular bed.

British journal of pharmacology 20081101

In vitro compared activity of telithromycin and azithromycin against northwest Italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility.

Letters in applied microbiology 20081001

Cellular imaging predictions of clinical drug-induced liver injury.

Toxicological sciences : an official journal of the Society of Toxicology 20080901

Telithromycin pharmacokinetics in rat model of diabetes mellitus induced by alloxan or streptozotocin.

Pharmaceutical research 20080801

Telithromycin inhibits the production of proinflammatory mediators and the activation of NF-kappaB in in vitro-stimulated murine cells.

FEMS immunology and medical microbiology 20080801

The intracellular accumulation of phagocytic and epithelial cells and the inhibitory effect on Chlamydophila (Chlamydia) pneumoniae of telithromycin and comparator antimicrobials.

Journal of chemotherapy (Florence, Italy) 20080801

Effects of telithromycin in in vitro and in vivo models of lipopolysaccharide-induced airway inflammation.

Chest 20080701

In vitro activity of telavancin against resistant gram-positive bacteria.

Antimicrobial agents and chemotherapy 20080701

[New antibiotics].

La Revue de medecine interne 20080601

Antimicrobial susceptibility of respiratory tract pathogens in Japan during PROTEKT years 1-5 (1999-2004).

Microbial drug resistance (Larchmont, N.Y.) 20080601

Clinical efficacy and time to symptom resolution of 5-day telithromycin versus 10-day amoxicillin-clavulanate in the treatment of acute bacterial sinusitis.

Current medical research and opinion 20080601

Subinhibitory concentrations of telithromycin, clarithromycin and azithromycin reduce methicillin-resistant Staphylococcus aureus coagulase in vitro and in vivo.

The Journal of antimicrobial chemotherapy 20080301

Increasing telithromycin resistance among Streptococcus pyogenes in Europe.

The Journal of antimicrobial chemotherapy 20080301

Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections.

Expert opinion on pharmacotherapy 20080201

Telithromycin and the FDA: implications for the future.

The Lancet. Infectious diseases 20080201

Levofloxacin-resistant Helicobacter pylori in Hong Kong.

Chemotherapy 20080101

Elevated hepatic transaminases associated with telithromycin therapy: a case report and literature review.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080101

Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1-4.

Annals of clinical microbiology and antimicrobials 20080101

In vitro activity of telithromycin against Haemophilus influenzae at epithelial lining fluid concentrations.

BMC microbiology 20080101

Benefit-risk assessment of telithromycin in the treatment of community-acquired pneumonia.

Drug safety 20080101

[Susceptibility of Staphylococcus aureus to new macrolide antibiotics].

Przeglad lekarski 20080101

Accessing FDA approval packages and briefing documents.

The Annals of pharmacotherapy 20071201

Emergence of telithromycin resistance in Haemophilus influenzae in Japan.

Journal of medical microbiology 20071201

[Recent results of multinational studies on antibiotic resistance: should we have 'PROTECTion' against these resistances?].

Medecine et maladies infectieuses 20071101

Susceptibility of oral obligate anaerobes to telithromycin, moxifloxacin and a number of commonly used antibacterials.

Oral microbiology and immunology 20071001

Susceptibilities of Streptococcus pyogenes and Streptococcus pneumoniae to macrolides and telithromycin: data from an Italian multicenter study.

Journal of chemotherapy (Florence, Italy) 20071001

Novel tethers in ketolide antibiotics.

Bioorganic & medicinal chemistry letters 20070915

Synthesis and antibacterial activity of C11, C12-cyclic urea analogues of ketolides.

Bioorganic & medicinal chemistry letters 20070915

In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe.

Antimicrobial agents and chemotherapy 20070901

Regional trends in beta-lactam, macrolide, fluoroquinolone and telithromycin resistance among Streptococcus pneumoniae isolates 2001-2004.

The Journal of infection 20070801

Acute hepatitis attack after exposure to telithromycin.

Clinical therapeutics 20070801

Activity of telithromycin and comparators against isolates of Legionella pneumophila collected from patients with community-acquired respiratory tract infections: PROTEKT Years 1-5.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20070701

Activities of clindamycin, synercid, telithromycin, linezolid, and mupirocin against Gram-positive coccal strains resistant to erythromycin in Korea.

Archives of pharmacal research 20070701

Activities of 16-membered ring macrolides and telithromycin against different genotypes of erythromycin-susceptible and erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae.

The Journal of antimicrobial chemotherapy 20070601

Telithromycin: the perils of hasty adoption and persistence of off-label prescribing.

Journal of managed care pharmacy : JMCP 20070601

Effective integration of medical and pharmacy claims to better protect patient safety--a long road yet to travel.

Journal of managed care pharmacy : JMCP 20070601

The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3.

Drug metabolism and disposition: the biological fate of chemicals 20070501

EDP-420, a bicyclolide (bridged bicyclic macrolide), is active against Mycobacterium avium.

Antimicrobial agents and chemotherapy 20070501

Effects of acute renal failure on the pharmacokinetics of telithromycin in rats: negligible effects of increase in CYP3A1 on the metabolism of telithromycin.

Biopharmaceutics & drug disposition 20070501

The FDA and the case of Ketek.

The New England journal of medicine 20070419

Ketek--the FDA perspective.

The New England journal of medicine 20070419

Resistance phenotypes conferred by macrolide phosphotransferases.

FEMS microbiology letters 20070401

Re: Acute bacterial rhinosinusitis--a review of US treatment guidelines.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20070401

Comparative in vitro and bactericidal activities of telithromycin against penicillin-nonsusceptible, levofloxacin-resistant, and macrolide-resistant Streptococcus pneumoniae by time-kill methodology.

International journal of antimicrobial agents 20070301

The anti-inflammatory activity of telithromycin in a mouse model of septic shock.

International journal of antimicrobial agents 20070301

Telithromycin-induced TEN: report of a case.

Archives of dermatology 20070301

[Macrolides and ketolides].

Nihon rinsho. Japanese journal of clinical medicine 20070227

Role for 5-day, once-daily extended-release clarithromycin in acute bacterial exacerbation of chronic bronchitis.

Current medical research and opinion 20070201

In vitro activities of oral cephem and telithromycin against clinical isolates of major respiratory pathogens in Japan.

Journal of Korean medical science 20070201

Recent findings from multinational resistance surveys: are we 'PROTEKTed' from resistance?

International journal of antimicrobial agents 20070201

The first telithromycin-resistant Streptococcus pneumoniae isolate in Japan associated with erm(B) and mutations in 23S rRNA and riboprotein L4.

Japanese journal of infectious diseases 20070201

Leber's hereditary optic neuropathy associated with cocaine, ecstasy and telithromycin consumption.

Journal of neurology 20070201

Limit Ketek to pneumonia, experts advise: advisers urge black-box warning.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070115

Pharmacokinetics of telithromycin using bronchoscopic microsampling after single and multiple oral doses.

Pulmonary pharmacology & therapeutics 20070101

Human serum activity of telithromycin, azithromycin and amoxicillin/clavulanate against common aerobic and anaerobic respiratory pathogens.

International journal of antimicrobial agents 20070101

Telithromycin inhibits the number of viable bacteria but not lymphocyte accumulation in a murine model of chronic respiratory infection.

Chemotherapy 20070101

Apparent anaphylactoid reaction after treatment with a single dose of telithromycin.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20070101

Time-kill kinetics of Streptococcus pneumoniae with reduced susceptibility to telithromycin.

Chemotherapy 20070101

[In vitro susceptibility of respiratory isolates of Streptococcus pneumoniae and Streptococcus pyogenes to telithromycin and 11 other antimicrobial agents: Turkish results of e-BASKETT-II surveillance study].

Mikrobiyoloji bulteni 20070101

Dose-dependent pharmacokinetics of telithromycin after intravenous and oral administration to rats: contribution of intestinal first-pass effect to low bioavailability.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101

Comparative activities of antibiotics against intracellular non-typeable Haemophilus influenzae.

Wiener klinische Wochenschrift 20070101

Telithromycin use and spontaneous reports of hepatotoxicity.

Drug safety 20070101

Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies.

Clinical pharmacokinetics 20070101

In vitro activity of telithromycin and quinupristin/dalfopristin against methicillin-resistant coagulase-negative staphylococci with defined resistance genotypes.

Folia microbiologica 20070101

Myasthenia gravis exacerbation or unmasking associated with telithromycin treatment.

Neurology 20061226

Synthesis and antibacterial activity of C6-carbazate ketolides.

Bioorganic & medicinal chemistry letters 20061215

Telithromycin and myasthenic crisis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061215

Telithromycin and acute liver failure.

The New England journal of medicine 20061123

Severe hepatotoxicity of telithromycin.

Annals of internal medicine 20060919

In vitro effects of penicillin and telithromycin on the expression of Streptococcus pneumoniae capsule.

The Journal of antimicrobial chemotherapy 20060901

In vivo efficacy of telithromycin on cytokine and nitric oxide formation in lipopolysaccharide-induced acute systemic inflammation in mice.

The Journal of antimicrobial chemotherapy 20060901

Treatment of experimental chronic pulmonary mycoplasmosis.

International journal of antimicrobial agents 20060901

Synthesis and antibacterial activity of novel C12 ethyl ketolides.

Bioorganic & medicinal chemistry 20060815

Telithromycin in acute exacerbations of asthma.

The New England journal of medicine 20060706

Telithromycin in acute exacerbations of asthma.

The New England journal of medicine 20060706

Telithromycin in acute exacerbations of asthma.

The New England journal of medicine 20060706

Telithromycin in acute exacerbations of asthma.

The New England journal of medicine 20060706

Investigation of inducible clindamycin and telithromycin resistance in isolates of beta-hemolytic streptococci.

Diagnostic microbiology and infectious disease 20060701

Differentiation of arrhythmia risk of the antibacterials moxifloxacin, erythromycin, and telithromycin based on analysis of monophasic action potential duration alternans and cardiac instability.

The Journal of pharmacology and experimental therapeutics 20060701

[Successful telithromycin therapy of Legionella pneumonia --report of three cases].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20060701

Old dogs that learn new tricks: modified antimicrobial agents that escape pre-existing resistance mechanisms.

International journal of medical microbiology : IJMM 20060601

Telithromycin-induced digoxin toxicity and electrocardiographic changes.

Pharmacotherapy 20060601

Pharmacodynamics: relation to antimicrobial resistance.

The American journal of medicine 20060601

Pill esophagitis caused by telithromycin: a case report.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20060601

A fine pile of paté: the cautionary tale of telithromycin, hepatic failure, and study 3014.

Surgical infections 20060601

Telithromycin in lower respiratory tract infections.

Future microbiology 20060601

Effect of a newly developed ketolide antibiotic, telithromycin, on metabolism of theophylline and expression of cytochrome P450 in rats.

Life sciences 20060530

[Potential interaction between telitromicin and acenocumarol].

Medicina clinica 20060527

Clinical implications and treatment of multiresistant Streptococcus pneumoniae pneumonia.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060501

What's new in clinical pharmacology and therapeutics.

WMJ : official publication of the State Medical Society of Wisconsin 20060501

Fraud, errors taint a key study of widely used Sanofi drug; despite some faked results, FDA approves antibiotic; one doctor's cocaine use; company defends safety.

Wall Street journal (Eastern ed.) 20060501

The effect of telithromycin in acute exacerbations of asthma.

The New England journal of medicine 20060413

Treating acute asthma with antibiotics--not quite yet.

The New England journal of medicine 20060413

Clinical and bacteriologic efficacy of telithromycin in patients with bacteremic community-acquired pneumonia.

Respiratory medicine 20060401

Synthesis and antibacterial activity of 6-O-heteroarylcarbamoyl-11,12-lactoketolides.

Bioorganic & medicinal chemistry letters 20060401

Drug interactions during therapy with three major groups of antimicrobial agents.

Expert opinion on pharmacotherapy 20060401

Effect of telithromycin and azithromycin on nasopharyngeal bacterial flora in patients with acute maxillary sinusitis.

Archives of otolaryngology--head & neck surgery 20060401

In vivo immunomodulatory profile of telithromycin in a murine pneumococcal infection model.

Die Pharmazie 20060401

Antibiotics for treatment of resistant gram-positive coccal infections.

Indian journal of pediatrics 20060401

Summaries for patients. Telithromycin: a possible cause of severe liver damage?

Annals of internal medicine 20060321

Brief communication: severe hepatotoxicity of telithromycin: three case reports and literature review.

Annals of internal medicine 20060321

Telithromycin.

Annals of internal medicine 20060321

In vitro activity of telithromycin against Gram-negative bacterial pathogens.

The Journal of infection 20060301

Telithromycin in the treatment of pneumococcal community-acquired respiratory tract infections: a review.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20060301

Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides.

Bioorganic & medicinal chemistry letters 20060301

Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide.

Clinical pharmacology and therapeutics 20060301

[Clinicoradiological diagnosis of respiratory infections: estimate of pathogens by radiological findings and the strategy for treatment].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20060301

Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives.

Bioorganic & medicinal chemistry letters 20060215

An in vitro study of the activity of telithromycin against mobile and cystic forms of Borrelia afzelii.

Infection 20060201

Sampling the antibiotic resistome.

Science (New York, N.Y.) 20060120

A review of guidelines for antibacterial use in acute exacerbations of chronic bronchitis.

Pulmonary pharmacology & therapeutics 20060101

[Antimicrobial resistance of Streptococcus pneumoniae strains isolated in the Reunion Island during 2004].

Medecine et maladies infectieuses 20060101

Microbiological assay for the determination of telithromycin in tablets.

Journal of AOAC International 20060101

New safety information on Ketek.

FDA consumer 20060101

Trends in anti-bacterial resistance among Streptococcus pneumoniae isolated in the USA, 2000-2003: PROTEKT US years 1-3.

The Journal of infection 20051201

Resistance to telithromycin is conferred by msr(A), msrC and msr(D) in Staphylococcus aureus.

The Journal of antimicrobial chemotherapy 20051201

Susceptibility of Streptococcus pneumoniae to penicillin, azithromycin and telithromycin (PROTEKT 1999-2003).

International journal of antimicrobial agents 20051201

Activity of five quinolones, three macrolides and telithromycin against 12 Haemophilus influenzae strains with different resistance phenotypes.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20051201

Activity of telithromycin against thirteen new isolates of C. burnetii including three resistant to doxycycline.

Annals of the New York Academy of Sciences 20051201

Methyltransferase Erm(37) slips on rRNA to confer atypical resistance in Mycobacterium tuberculosis.

The Journal of biological chemistry 20051125

The PROTEKT global study (year 4) demonstrates a continued lack of resistance development to telithromycin in Streptococcus pneumoniae.

The Journal of antimicrobial chemotherapy 20051001

Resistance to macrolides, clindamycin and telithromycin in Streptococcus pyogenes isolated in Spain during 2004.

The Journal of antimicrobial chemotherapy 20051001

Evaluation of telithromycin against Streptococcus pneumoniae with ribosomal mutations utilizing in vitro time-kill methodology.

International journal of antimicrobial agents 20051001

Intrapulmonary concentrations of telithromycin: clinical implications for respiratory tract infections due to Streptococcus pneumoniae.

Chemotherapy 20051001

Efficacy of oral telithromycin in community-acquired pneumonia caused by resistant Streptococcus pneumoniae.

The Journal of infection 20051001

Five-day telithromycin once daily is as effective as 10-day clarithromycin twice daily for the treatment of acute exacerbations of chronic bronchitis and is associated with reduced health-care resource utilization.

Chest 20051001

Pharmacokinetics of telithromycin: application to dosing in the treatment of community-acquired respiratory tract infections.

Current medical research and opinion 20051001

[Efficacy and safety of extended-release clarithromycin (5-day short-course) vs telithromycin, in acute bacterial exacerbation of chronic bronchitis].

Medecine et maladies infectieuses 20051001

In vitro activity of beta-lactams, macrolides, telithromycin, and fluoroquinolones against clinical isolates of Streptococcus pneumoniae: correlation between drug resistance and genetic characteristics.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20051001

Kinetic bactericidal activity of telithromycin, azithromycin and clarithromycin against respiratory pathogens.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20051001

Activity of telithromycin against multi-drug resistant Streptococcus pneumoniae and molecular characterization of macrolide and tetracycline resistance determinants.

Journal of chemotherapy (Florence, Italy) 20051001

Mechanisms of resistance to telithromycin in Streptococcus pneumoniae.

The Journal of antimicrobial chemotherapy 20050901

Demographic analysis of antimicrobial resistance among Streptococcus pneumoniae: worldwide results from PROTEKT 1999-2000.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20050901

Amoxicillin/telithromycin-induced rash in infectious mononucleosis.

The Annals of pharmacotherapy 20050901

Molecular basis of macrolide resistance in Campylobacter: role of efflux pumps and target mutations.

The Journal of antimicrobial chemotherapy 20050901

The bioequivalence of telithromycin administered orally as crushed tablets versus tablets swallowed whole.

Journal of clinical pharmacology 20050901

Comparative pharmacodynamics of telithromycin and clarithromycin with Streptococcus pneumoniae and Staphylococcus aureus in an in vitro dynamic model: focus on clinically achievable antibiotic concentrations.

International journal of antimicrobial agents 20050901

Telithromycin for the treatment of acute bacterial maxillary sinusitis: a review of a new antibacterial agent.

Southern medical journal 20050901

[Efficacy and safety of telithromycin in the treatment of acute exacerbation of chronic obstructive pulmonary disease].

Medecine et maladies infectieuses 20050901

[Implication of ermX genes in macrolide- and telithromycin-resistance in Corynebacterium jeikeium and Corynebacterium amycolatum].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20050901

Telithromycin-resistant Streptococcus pneumoniae.

Emerging infectious diseases 20050901

Determination of telithromycin in human plasma and microdialysates by high-performance liquid chromatography.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805

Assessment of the effect of a single oral dose of telithromycin on sotalol-induced qt interval prolongation in healthy women.

British journal of clinical pharmacology 20050801

Telithromycin: the first ketolide antimicrobial.

Clinical therapeutics 20050801

Impact of carbon dioxide on the susceptibility of key respiratory tract pathogens to telithromycin and azithromycin.

The Journal of antimicrobial chemotherapy 20050701

In vitro activity of telithromycin against respiratory tract pathogens in comparison with other antimicrobial agents.

Chemotherapy 20050701

Efficacy of telithromycin in community-acquired pneumonia caused by pneumococci with reduced susceptibility to penicillin and/or erythromycin.

Chemotherapy 20050701

Telithromycin: a ketolide antibiotic for treatment of respiratory tract infections.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050601

Assessment of the efficacy of telithromycin simulating human exposures against S. pneumoniae with ribosomal mutations in a murine pneumonia model.

International journal of antimicrobial agents 20050601

Macrolide- and telithromycin-resistant Streptococcus pyogenes, Belgium, 1999-2003.

Emerging infectious diseases 20050601

[In vitro antibacterial activities of telithromycin against clinical isolates of Neisseria gonorrhoeae].

The Japanese journal of antibiotics 20050601

Telithromycin: do we really need this antimicrobial?

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050501

Telithromycin: the first ketolide for the treatment of respiratory infections.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050501

Pharmacodynamics of an 800-mg dose of telithromycin in patients with community-acquired pneumonia caused by extracellular pathogens.

Diagnostic microbiology and infectious disease 20050501

Susceptibilities of Neisseria gonorrhoeae and Ureaplasma urealyticum isolates from male patients with urethritis to several antibiotics including telithromycin.

Chemotherapy 20050501

Adverse drug reactions in Canada.

Canadian family physician Medecin de famille canadien 20050501

Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.

Cell 20050422

Telithromycin activity is reduced by efflux in Streptococcus pyogenes.

The Journal of antimicrobial chemotherapy 20050401

Macrolide-resistance mechanisms in Streptococcus pneumoniae isolates from Belgium.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050401

Penetration of telithromycin into the nasal mucosa and ethmoid bone of patients undergoing rhinosurgery for chronic sinusitis.

The Journal of antimicrobial chemotherapy 20050401

Clinical and bacteriological efficacy of 5-day telithromycin in acute maxillary sinusitis: a pooled analysis.

The Journal of infection 20050401

In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.

Antimicrobial agents and chemotherapy 20050401

[Efficacy and safety of telithromycin in the treatment of acute maxillary sinusitis].

Medecine et maladies infectieuses 20050401

[In vitro activity of telithromycin against community acquired respiratory pathogens].

Revista medica de Chile 20050401

Synthesis and biological activity of new 5-O-sugar modified ketolide and 2-fluoro-ketolide antibiotics.

Bioorganic & medicinal chemistry letters 20050301

Bacteriological efficacy of 5-day therapy with telithromycin in acute maxillary sinusitis.

International journal of antimicrobial agents 20050301

Ketolides: new antimicrobials for community-acquired pneumonia.

Home healthcare nurse 20050301

Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment.

International journal of clinical pharmacology and therapeutics 20050301

Telithromycin for the treatment of acute exacerbations of chronic bronchitis.

International journal of clinical practice 20050301

Verapamil toxicity resulting from a probable interaction with telithromycin.

The Annals of pharmacotherapy 20050201

In vitro activity of telithromycin against mefA and ermB erythromycin-resistant viridans streptococci isolated from bacteremia of oral origin in Spain.

Oral microbiology and immunology 20050201

Telithromycin new product overview.

The Journal of allergy and clinical immunology 20050201

2004 drug approval highlights: FDA update.

The Nurse practitioner 20050201

Antibiotic activity of telithromycin and comparators against bacterial pathogens isolated from 3,043 patients with acute exacerbation of chronic bronchitis.

Annals of clinical microbiology and antimicrobials 20050101

Pharmacodynamic analysis of the microbiological efficacy of telithromycin in patients with community-acquired pneumonia.

Clinical pharmacokinetics 20050101

Effects of itraconazole or grapefruit juice on the pharmacokinetics of telithromycin.

Pharmacotherapy 20050101

Telithromycin--a ketolide antibiotic for the treatment of outpatients with community-acquired respiratory tract infections.

Clinical nurse specialist CNS 20050101

Efficacy and safety of telithromycin 800 mg once daily for 7 days in community-acquired pneumonia: an open-label, multicenter study.

BMC infectious diseases 20050101

Clinical pharmacokinetics of telithromycin, the first ketolide antibacterial.

Clinical pharmacokinetics 20050101

Characterization of erythromycin-resistant Streptococcus pneumoniae in Korea, and In Vitro activity of telithromycin against erythromycin-resistant Streptococcus pneumoniae.

Microbial drug resistance (Larchmont, N.Y.) 20050101

Pharmacodynamic activity of telithromycin against macrolide-susceptible and macrolide-resistant Streptococcus pneumoniae simulating clinically achievable free serum and epithelial lining fluid concentrations.

The Journal of antimicrobial chemotherapy 20041201

Activity of telithromycin against erythromycin-susceptible and -resistant Streptococcus pneumoniae isolates from adults with invasive infections.

International journal of antimicrobial agents 20041201

Introduction to PROTEkT: years 1-3 (1999-2002).

Journal of chemotherapy (Florence, Italy) 20041201

PROTEKT years 1-3 (1999-2002): study design and methodology.

Journal of chemotherapy (Florence, Italy) 20041201

Resistance trends in Streptococcus pneumoniae (PROTEKT years 1-3 [1999-2002]).

Journal of chemotherapy (Florence, Italy) 20041201

Global distribution of Streptococcus pneumoniae serotypes isolated from paediatric patients during 1999-2000 and the in vitro efficacy of telithromycin and comparators.

Journal of medical microbiology 20041101

[Pharmacoeconomic analysis of patients with acute exacerbation of chronic bronchitis treated with telithromycin or cefuroxime-axetil].

Revista clinica espanola 20041101

Development of macrolide-resistance and comparative activity of telithromycin in streptococci in Austria, 1996-2002.

International journal of antimicrobial agents 20041001

An examination of the differential sensitivity to ketolide antibiotics in ermB strains of Streptococcus pyogenes and Streptococcus pneumoniae.

Current microbiology 20041001

Telithromycin.

Expert review of anti-infective therapy 20041001

[Molecular analytical evaluation of macrolide- and ketolide-resistant Streptococcus pneumoniae--mechanism of action of telithromycin and resistance to it].

The Japanese journal of antibiotics 20041001

Synthesis and antibacterial activity of C-6 carbamate ketolides, a novel series of orally active ketolide antibiotics.

Bioorganic & medicinal chemistry letters 20040906

Potential interaction between telithromycin and warfarin.

The Annals of pharmacotherapy 20040901

Macrolides and ketolides: azithromycin, clarithromycin, telithromycin.

Infectious disease clinics of North America 20040901

Telithromycin (Ketek) for community-acquired respiratory tract infections.

The Nurse practitioner 20040901

Efficacy and safety of oral telithromycin once daily for 5 days versus moxifloxacin once daily for 10 days in the treatment of acute bacterial rhinosinusitis.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20040901

Telithromycin.

Nature reviews. Drug discovery 20040901

New drugs.

Canadian family physician Medecin de famille canadien 20040901

Telithromycin (Ketek) for respiratory infections.

The Medical letter on drugs and therapeutics 20040816

Selection of resistance of telithromycin against Haemophilus influenzae, Moraxella catarrhalis and streptococci in comparison with macrolides.

The Journal of antimicrobial chemotherapy 20040801

Activity of telithromycin against key pathogens associated with community-acquired respiratory tract infections.

The Journal of infection 20040801

Telithromycin-induced acute interstitial nephritis: a first case report.

American journal of kidney diseases : the official journal of the National Kidney Foundation 20040801

Antibacterial susceptibility among Streptococcus pneumoniae isolated from paediatric and adult patients as part of the PROTEKT US study in 2001-2002.

The Journal of antimicrobial chemotherapy 20040801

Clinical and bacteriological efficacy and safety of 5 and 7 day regimens of telithromycin once daily compared with a 10 day regimen of clarithromycin twice daily in patients with mild to moderate community-acquired pneumonia.

The Journal of antimicrobial chemotherapy 20040801

Efficacy of telithromycin in community-acquired pneumonia caused by Legionella pneumophila.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20040801

PROTEKT US: results from the second year of this longitudinal surveillance study of antimicrobial resistance among respiratory tract pathogens isolated from paediatric and adult patients in the USA. Introduction.

The Journal of antimicrobial chemotherapy 20040801

Evaluation of 5-day therapy with telithromycin, a novel ketolide antibacterial, for the treatment of tonsillopharyngitis.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040701

Hospitalization rates among patients with community-acquired pneumonia treated with telithromycin vs clarithromycin: results from two randomized, double-blind, clinical trials.

Current medical research and opinion 20040701

Treatment of acute Chlamydia pneumoniae infection with telithromycin in C57BL/6J mice.

The Journal of antimicrobial chemotherapy 20040601

Clinical efficacy of ketolides in the treatment of respiratory tract infections.

The Journal of antimicrobial chemotherapy 20040601

Macrolide resistance phenotypes of commensal viridans group streptococci and Gemella spp. and PCR detection of resistance genes.

International journal of antimicrobial agents 20040601

Antibacterial resistance of community-acquired respiratory tract pathogens recovered from patients in Germany and activity of the Ketolide Telithromycin: results from the PROTEKT surveillance study (1999-2000).

Chemotherapy 20040601

In vitro activity of telithromycin, quinupristin/dalfopristin, linezolid and comparator antimicrobial agents against Staphylococcus aureus clinical isolates.

Journal of chemotherapy (Florence, Italy) 20040601

Pneumococcal resistance to macrolides, lincosamides, ketolides, and streptogramin B agents: molecular mechanisms and resistance phenotypes.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040515

Comparative in vitro activity of telithromycin against macrolide-resistant and -susceptible Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae.

The Journal of antimicrobial chemotherapy 20040501

Comparative study of the in vitro activity of a new fluoroquinolone, ABT-492.

The Journal of antimicrobial chemotherapy 20040501

Comparison of hospitalization rates in patients with community-acquired pneumonia treated with telithromycin for 5 or 7 days or clarithromycin for 10 days.

Current medical research and opinion 20040501

Comparison of hospitalization rates in patients with community-acquired pneumonia treated with 10 days of telithromycin or clarithromycin.

Current medical research and opinion 20040501

Comparison of the in vitro efficacy of telithromycin (HMR 3647) and levofloxacin with 22 antibiotic compounds against Bosea and Afipia species.

The Journal of antimicrobial chemotherapy 20040401

Streptococcus pneumoniae and Streptococcus pyogenes isolated from a paediatric population in Great Britain and Ireland: the in vitro activity of telithromcycin versus comparators.

The Journal of infection 20040401

Comparative in vitro activity of telithromycin and beta-lactam antimicrobials against community-acquired bacterial respiratory tract pathogens in the United States: findings from the PROTEKT US study, 2000-2001.

Clinical therapeutics 20040401

Pharmacokinetics and safety of the ketolide telithromycin in patients with renal impairment.

Journal of clinical pharmacology 20040301

[Telithromycin].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20040301

Efficacy of telithromycin in the treatment of experimental Bacteroides fragilis intraabdominal abscess in the senescent mice.

Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20040301

Tissue kinetics of telithromycin, the first ketolide antibacterial.

The Journal of antimicrobial chemotherapy 20040201

Clinical use of antimicrobial pharmacodynamic profiles to optimise treatment outcomes in community-acquired bacterial respiratory tract infections: application to telithromycin.

Expert opinion on pharmacotherapy 20040201

Comparative activity of telithromycin against macrolide-resistant isolates of Streptococcus pneumoniae: results of two years of the PROTEKT surveillance study.

Journal of chemotherapy (Florence, Italy) 20040201

[Telithromycin].

Klinicka mikrobiologie a infekcni lekarstvi 20040201

Antibacterial resistance among children with community-acquired respiratory tract infections (PROTEKT 1999-2000).

The Journal of infection 20040101

Clinical and bacteriological efficacy of the ketolide telithromycin against isolates of key respiratory pathogens: a pooled analysis of phase III studies.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040101

[How effective are linezolid and telithromycin? The resistance situation of pathogenic gram positive infections in Germany].

Pharmazie in unserer Zeit 20040101

[Two new antibiotics with special qualities: the pharmacokinetics of linezolid and telithromycin].

Pharmazie in unserer Zeit 20040101

[Importance in respiratory tract infections. Ketolides: clinical aspects].

Pharmazie in unserer Zeit 20040101

[Adverse effects of anti-infectives. Undesirable effects and interactions of ketolides and oxazolidonones].

Pharmazie in unserer Zeit 20040101

Efficacy and tolerability of once-daily oral telithromycin compared with clarithromycin for the treatment of community-acquired pneumonia in adults.

Clinical therapeutics 20040101

[Activity of telithromycin and other oral antibiotics against respiratory tract pathogens with acquired mechanisms of resistance].

Enfermedades infecciosas y microbiologia clinica 20040101

Telithromycin.

Drugs 20040101

Telithromycin: a brief review of a new ketolide antibiotic.

Journal of drugs in dermatology : JDD 20040101

[Management of communal lower respiratory tract infections in the emergency ward: the role of Ketek (telithromycine)].

Medecine et maladies infectieuses 20040101

Recently introduced antibiotics: a guide for the general physician.

Clinical medicine (London, England) 20040101

Telithromycin and myasthenia gravis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031201

Optimizing outcomes with antimicrobial therapy through pharmacodynamic profiling.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201

Penetration of oral telithromycin into female genital tissues.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201

[Evaluation of ketoride antibiotics, telithromycin in treatment of respiratory tract infections (discussion)].

The Japanese journal of antibiotics 20031201

Telithromycin post-antibiotic and post-antibiotic sub-MIC effects for 10 Gram-positive cocci.

The Journal of antimicrobial chemotherapy 20031101

In vitro activity of newer antibiotics against Corynebacterium jeikeium, Corynebacterium amycolatum and Corynebacterium urealyticum.

International journal of antimicrobial agents 20031101

In vitro activity of telithromycin compared with macrolides and fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis.

International journal of antimicrobial agents 20031101

Ketolides: an emerging treatment for macrolide-resistant respiratory infections, focusing on S. pneumoniae.

Expert opinion on emerging drugs 20031101

Inhibitory action of telithromycin against Shiga toxin and endotoxin.

Biochemical and biophysical research communications 20031031

Induction of telithromycin resistance in Streptococcus pneumoniae.

The Journal of antimicrobial chemotherapy 20031001

A pooled analysis of telithromycin in the treatment of community-acquired respiratory tract infections in adults.

Infection 20031001

[Digitalis -- poisoning, myopathy, ergotism.... When antibiotic and associated therapy become dangerous mixture].

MMW Fortschritte der Medizin 20030925

Comparative activity of telithromycin against typical community-acquired respiratory pathogens.

The Journal of antimicrobial chemotherapy 20030901

High-level telithromycin resistance in laboratory-generated mutants of Streptococcus pneumoniae.

The Journal of antimicrobial chemotherapy 20030901

Ketolides: a new class of antibacterial agents for treatment of community-acquired respiratory tract infections in a primary care setting.

Mayo Clinic proceedings 20030901

In vitro activities of new ketolide, telithromycin, and eight other macrolide antibiotics against Streptococcus pneumoniae having mefA and ermB genes that mediate macrolide resistance.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20030901

[The 3 molecules of the year].

Revue medicale de Bruxelles 20030901

[Pharmacoeconomic analysis of community-acquired pneumonia treatment with telithromycin or clarithromycin].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20030901

Pharmacokinetics of the ketolide telithromycin after single and repeated doses in patients with hepatic impairment.

International journal of antimicrobial agents 20030801

Comparative in vitro activity of telithromycin and beta-lactam antimicrobials against bacterial pathogens from community-acquired respiratory tract infections: data from the first year of PROTEKT (1999-2000).

Journal of chemotherapy (Florence, Italy) 20030801

Interaction of macrolides and ketolides with the phagocytic cell line PLB-985.

Journal of chemotherapy (Florence, Italy) 20030801

Efficacy and tolerability of telithromycin for 5 or 10 days vs amoxicillin/clavulanic acid for 10 days in acute maxillary sinusitis.

Ear, nose, & throat journal 20030801

Streptococcus pyogenes isolates with characterized macrolide resistance mechanisms in Spain: in vitro activities of telithromycin and cethromycin.

The Journal of antimicrobial chemotherapy 20030701

Selection of ketolide resistance in Staphylococcus aureus.

International journal of antimicrobial agents 20030701

Activity of telithromycin and seven other agents against 1034 pediatric Streptococcus pneumoniae isolates from ten central and eastern European centers.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701

Telithromycin 800 mg once daily for seven to ten days is an effective and well-tolerated treatment for community-acquired pneumonia.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701

In vitro activity of telithromycin (HMR 3647) against Greek Streptococcus pyogenes and Streptococcus pneumoniae clinical isolates with different macrolide susceptibilities.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701

Activity of telithromycin compared with seven other agents against 1039 Streptococcus pyogenes pediatric isolates from ten centers in central and eastern Europe.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701

[Telithromycin in the management of lower respiratory tract infections in the hospital].

Presse medicale (Paris, France : 1983) 20030607

Telithromycin in the treatment of community-acquired pneumonia: a pooled analysis.

Respiratory medicine 20030601

Efficacy and tolerability of once-daily oral therapy with telithromycin compared with trovafloxacin for the treatment of community-acquired pneumonia in adults.

International journal of clinical practice 20030601

[Telithromycin in daily practice in admission services and treatment of emergencies].

Presse medicale (Paris, France : 1983) 20030531

In vitro and in vivo antibacterial activities of telithromycin.

Chemotherapy 20030501

Telithromycin (HMR 3647) achieves high and sustained concentrations in tonsils of patients undergoing tonsillectomy.

International journal of antimicrobial agents 20030501

Community-acquired respiratory tract infections caused by resistant pneumococci: clinical and bacteriological efficacy of the ketolide telithromycin.

The Journal of antimicrobial chemotherapy 20030401

[Macrolides, ketolides and streptogramins].

Enfermedades infecciosas y microbiologia clinica 20030401

Drugs of the 21st century: telithromycin (HMR 3647)--the first ketolide.

The Journal of antimicrobial chemotherapy 20030301

Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects.

Clinical pharmacology and therapeutics 20030301

[New antibiotics in primary care].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20030301

[Resistance of respiratory tract infection agents is still increasing. Is its time for new antibiotic strategies?].

MMW Fortschritte der Medizin 20030227

Preferential inhibition of protein synthesis by ketolide antibiotics in Haemophilus influenzae cells.

Current microbiology 20030201

[Telithromycin, first ketolide].

Revue medicale de Bruxelles 20030201

Efficacy and tolerability of 5-day, once-daily telithromycin compared with 10-day, twice-daily clarithromycin for the treatment of group A beta-hemolytic streptococcal tonsillitis/pharyngitis: a multicenter, randomized, double-blind, parallel-group study.

Clinical therapeutics 20030201

Dead bugs don't mutate: susceptibility issues in the emergence of bacterial resistance.

Emerging infectious diseases 20030101

Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20030101

[Telithromycin and exacerbation in myasthenia gravis].

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20030101

Relief of symptoms in patients with group A beta-hemolytic streptococcus tonsillopharyngitis: comparison between telithromycin and penicillin V.

Scandinavian journal of infectious diseases 20030101

Oral telithromycin 800 mg once daily for 5 days versus cefuroxime axetil 500 mg twice daily for 10 days in adults with acute exacerbations of chronic bronchitis.

The Journal of international medical research 20030101

Telithromycin: the first ketolide antibacterial for the treatment of community-acquired respiratory tract infections.

International journal of clinical practice 20030101

A comparison of the efficacy of telithromycin versus cefuroxime axetil in the treatment of acute bacterial maxillary sinusitis.

American journal of rhinology 20030101

[Telithromycin, first ketolide to diversify the management of community-acquired respiratory tract infections. Importance in emergency care].

Presse medicale (Paris, France : 1983) 20021221

Comparison of the antibacterial activities of ampicillin, ciprofloxacin, clarithromycin, telithromycin and quinupristin/dalfopristin against intracellular non-typeable Haemophilus influenzae.

The Journal of antimicrobial chemotherapy 20021201

In vitro activity of quinupristin/dalfopristin, linezolid, telithromycin and comparator antimicrobial agents against 13 species of coagulase-negative staphylococci.

The Journal of antimicrobial chemotherapy 20021201

Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers.

Chemotherapy 20021201

Efficacy and tolerability of once-daily telithromycin compared with high-dose amoxicillin for treatment of community-acquired pneumonia.

Infection 20021201

Telithromycin inhibition of protein synthesis and 50S ribosomal subunit formation in Streptococcus pneumoniae cells.

Current microbiology 20021101

Telithromycin is as effective as amoxicillin/clavulanate in acute exacerbations of chronic bronchitis.

Respiratory medicine 20021101

[Efficacy trial in general practice substantiated. New antibiotic with strong effectiveness and tolerance].

MMW Fortschritte der Medizin 20021017

Ketolides: the future of the macrolides?

Current opinion in pharmacology 20021001

Comparative in vitro activity of penicillin G, levofloxacin, moxifloxacin, telithromycin, pristinamycin, quinupristin-dalfopristin and linezolid against ofloxacin-intermediate and -resistant Streptococcus pneumoniae.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20021001

The ketolide antibiotic ABT-773 is a specific inhibitor of translation and 50S ribosomal subunit formation in Streptococcus pneumoniae cells.

Current microbiology 20020901

Genotypic characterization of macrolide-resistant strains of Streptococcus pneumoniae isolated in Quebec, Canada, and in vitro activity of ABT-773 and telithromycin.

The Journal of antimicrobial chemotherapy 20020901

Prevalence of macrolide and tetracycline resistance mechanisms in Streptococcus pyogenes isolates and in vitro susceptibility to telithromycin.

The Journal of antimicrobial chemotherapy 20020901

Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study, and compatative in vitro activity of the ketolide, telithromycin.

The Journal of antimicrobial chemotherapy 20020901

Comparison of telithromycin, a new ketolide, with erythromycin and clarithromycin for the treatment of Haemophilus influenzae pneumonia in suckling, middle aged and senescent mice.

International journal of antimicrobial agents 20020901

From macrolides to ketolides: What is available for the treatment of outpatient respiratory tract infections?

Postgraduate medicine 20020901

In vitro activities of the ketolides ABT-773 and telithromycin and of three macrolides against genetically characterized isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis.

The Journal of antimicrobial chemotherapy 20020701

In vitro activity of linezolid, synercid and telithromycin against genetically defined high level fluoroquinolone-resistant methicillin-resistant Staphylococcus aureus.

International journal of antimicrobial agents 20020701

[Are ketolides replacing macrolides in chronic bronchitis?].

Der Internist 20020701

Introduction: PROTEKT against respiratory tract infection.