2,6-Diaminopurine
| Title | Journal |
|---|---|
| Structural context effects in the oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine to hydantoin products: electrostatics, base stacking, and base pairing. | Journal of the American Chemical Society 20120912 |
| Simulations of A-RNA duplexes. The effect of sequence, solute force field, water model, and salt concentration. | The journal of physical chemistry. B 20120823 |
| Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides. | Bioorganic & medicinal chemistry 20120615 |
| Long lifetime of hydrogen-bonded DNA basepairs by force spectroscopy. | Biophysical journal 20120516 |
| Synthesis and oligomerization of Fmoc/Boc-protected PNA monomers of 2,6-diaminopurine, 2-aminopurine and thymine. | Organic & biomolecular chemistry 20120128 |
| The 3' splice site of influenza A segment 7 mRNA can exist in two conformations: a pseudoknot and a hairpin. | PloS one 20120101 |
| Biotransformation of 2,6-diaminopurine nucleosides by immobilized Geobacillus stearothermophilus. | Biotechnology progress 20120101 |
| Enhanced topical and transdermal delivery of antineoplastic and antiviral acyclic nucleoside phosphonate cPr-PMEDAP. | Pharmaceutical research 20111201 |
| Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs. | Nature structural & molecular biology 20111001 |
| Di-μ-but-2-enoato-bis-[diaqua-bis(but-2-enoato)neodymium(III)] 2,6-diamino-purine disolvate. | Acta crystallographica. Section E, Structure reports online 20110901 |
| Pa0148 from Pseudomonas aeruginosa catalyzes the deamination of adenine. | Biochemistry 20110802 |
| Tetraaquabis(2,6-diamine-7H-purine-κN9)cobalt(II) benzene-1,2,4,5-tetracarboxylate tetrahydrate. | Acta crystallographica. Section C, Crystal structure communications 20110801 |
| Role of the heat capacity change in understanding and modeling melting thermodynamics of complementary duplexes containing standard and nucleobase-modified LNA. | Biochemistry 20110614 |
| ATP and its N⁶-substituted analogues: parameterization, molecular dynamics simulation and conformational analysis. | Journal of molecular modeling 20110501 |
| Two isomorphous transition metal complexes containing a protonated diaminopurine ligand: diaquabis(2,6-diamino-7H-purin-1-ium-κN9)bis(homophthalato-κO)nickel(II) tetrahydrate and the cobalt(II) analogue. | Acta crystallographica. Section C, Crystal structure communications 20110501 |
| Synthesis and antiviral activity of N9-[3-fluoro-2-(phosphonomethoxy)propyl] analogues derived from N6-substituted adenines and 2,6-diaminopurines. | Bioorganic & medicinal chemistry 20110401 |
| Novel ligands for a purine riboswitch discovered by RNA-ligand docking. | Chemistry & biology 20110325 |
| Bis(2,6-diamino-1H-purin-3-ium) di-μ-croconato-κ3O,O':O'';κ3O:O',O''-bis[tetraaqua(croconato-κ2O,O')neodymium(III)]. | Acta crystallographica. Section C, Crystal structure communications 20110101 |
| Comparative study between transcriptionally- and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms. | PLoS genetics 20110101 |
| An update on targeted gene repair in mammalian cells: methods and mechanisms. | Journal of biomedical science 20110101 |
| Study of camelpox virus pathogenesis in athymic nude mice. | PloS one 20110101 |
| Enzymatic synthesis of nucleosides by nucleoside phosphorylase co-expressed in Escherichia coli. | Journal of Zhejiang University. Science. B 20101101 |
| 2,6-Diamino-9H-purine monohydrate and bis(2,6-diamino-9H-purin-1-ium) 2-(2-carboxylatophenyl)acetate heptahydrate: two simple structures with very complex hydrogen-bonding schemes. | Acta crystallographica. Section C, Crystal structure communications 20101101 |
| Computational mutagenesis studies of hammerhead ribozyme catalysis. | Journal of the American Chemical Society 20100929 |
| Comparisons between chemical mapping and binding to isoenergetic oligonucleotide microarrays reveal unexpected patterns of binding to the Bacillus subtilis RNase P RNA specificity domain. | Biochemistry 20100921 |
| Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine. | Bioorganic & medicinal chemistry 20100915 |
| Antiviral treatment of chronic hepatitis B virus (HBV) infections. | Viruses 20100601 |
| Role of the adenine ligand on the stabilization of the secondary and tertiary interactions in the adenine riboswitch. | Journal of molecular biology 20100312 |
| Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation. | The Journal of organic chemistry 20100305 |
| Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine. | Biochemistry 20100302 |
| Characterization of plant sulfiredoxin and role of sulphinic form of 2-Cys peroxiredoxin. | Journal of experimental botany 20100301 |
| Long-range charge transfer through DNA by replacing adenine with diaminopurine. | Journal of the American Chemical Society 20100120 |
| Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. | AIDS research and therapy 20100101 |
| Effect of substituents on the excited-state dynamics of the modified DNA bases 2,4-diaminopyrimidine and 2,6-diaminopurine. | Physical chemistry chemical physics : PCCP 20100101 |
| Reactions of Pd(II) with chelate-tethered 2,6-diaminopurine derivatives: N3-coordination and reaction of the purine system. | Inorganic chemistry 20091207 |
| Probing metal-ion purine interactions at DNA minor-groove sites. | Inorganic chemistry 20091102 |
| Two isomorphous crotonatolanthanide complexes: tetra-mu-but-2-enoato-bis[diaqua(but-2-enoato)Ln]-2,6-diaminopurine (1/2) (Ln = Dy and Ho). | Acta crystallographica. Section C, Crystal structure communications 20091101 |
| Co-expression of recombinant nucleoside phosphorylase from Escherichia coli and its application. | Applied biochemistry and biotechnology 20091001 |
| Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives. | Marine drugs 20090901 |
| Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota. | Journal of molecular biology 20090605 |
| Monitoring RNA-ligand interactions using isothermal titration calorimetry. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy. | PloS one 20090101 |
| Primer fabrication using polymerase mediated oligonucleotide synthesis. | BMC genomics 20090101 |
| An ab initio study of substituent effects on the excited states of purine derivatives. | The journal of physical chemistry. A 20081204 |
| Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. | RNA (New York, N.Y.) 20080801 |
| Inhibition of the replication of hepatitis B virus in vitro by a novel 2,6-diaminopurine analog, beta-LPA. | Biochemical and biophysical research communications 20080502 |
| Density functional and experimental studies on the FT-IR and FT-Raman spectra and structure of 2,6-diamino purine and 6-methoxy purine. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080101 |
| Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage. | RNA (New York, N.Y.) 20080101 |
| Solid-phase synthesis of pseudo-complementary peptide nucleic acids. | Nature protocols 20080101 |
| Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways. | AIDS research and therapy 20080101 |
| Stability and mismatch discrimination of DNA duplexes containing 2,6-diaminopurine and 2-thiothymidine locked nucleic acid bases. | Nucleic acids symposium series (2004) 20080101 |
| [(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions. | Purinergic signalling 20070901 |
| The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors. | Bioorganic & medicinal chemistry 20070515 |
| Acyclic nucleoside phosphonate antivirals activate gene expression of monocyte chemotactic protein 1 and 3. | Journal of biomedical science 20070101 |
| DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions. | Antiviral therapy 20070101 |
| Characterization of copper(II) interactions with sinefungin, a nucleoside antibiotic: combined potentiometric, spectroscopic and DFT studies. | Bioinorganic chemistry and applications 20070101 |
| Self-complementary purines by quadruple hydrogen bonding. | Chemical communications (Cambridge, England) 20061113 |
| Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists. | ChemMedChem 20060901 |
| Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives. | European journal of pharmacology 20060701 |
| Calcium-stimulated guanosine--inosine nucleosidase from yellow lupin (Lupinus luteus). | Phytochemistry 20060701 |
| Three conserved guanosines approach the reaction site in native and minimal hammerhead ribozymes. | Biochemistry 20060613 |
| Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain. | Journal of molecular biology 20060609 |
| Exposure of mice to arsenic and/or benzo[a]pyrene does not increase the frequency of Aprt-deficient cells recovered from explanted skin of Aprt heterozygous mice. | Environmental and molecular mutagenesis 20060601 |
| Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine. | European journal of pharmacology 20060113 |
| Highly efficient strand invasion by peptide nucleic acid bearing optically pure lysine residues in its backbone. | Nucleic acids symposium series (2004) 20060101 |
| The kinetics of ligand binding by an adenine-sensing riboswitch. | Biochemistry 20051011 |
| Unrestricted accessibility of short oligonucleotides to RNA. | RNA (New York, N.Y.) 20050901 |
| Synthesis, characterisation and theoretical calculations of 2,6-diaminopurine etheno derivatives. | Organic & biomolecular chemistry 20050821 |
| Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site. | Biochemistry 20050531 |
| An investigation of prebiotic purine synthesis from the hydrolysis of HCN polymers. | Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20050401 |
| Evidence for Watson-Crick and not Hoogsteen or wobble base pairing in the selection of nucleotides for insertion opposite pyrimidines and a thymine dimer by yeast DNA pol eta. | Biochemistry 20050329 |
| Evidence for three thymine DNA glycosylases in human cell extracts: substrate specificities of thymine DNA glycosylase activities. | Medical science monitor : international medical journal of experimental and clinical research 20050201 |
| Atomic force microscopy study of the structural effects induced by echinomycin binding to DNA. | Journal of molecular biology 20050128 |
| Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues. | European journal of pharmacology 20041006 |
| Modified bases in RNA reduce secondary structure and enhance hybridization. | Biochemistry 20040810 |
| Identification of the major tautomer for an etheno adduct of 2,6-diaminopurine by determination of the sign of (n)J(H,C). | Organic letters 20040805 |
| Influence of minor groove substituents on the structure of DNA Holliday junctions. | Biochemistry 20040803 |
| Syntheses and base-pairing properties of locked nucleic acid nucleotides containing hypoxanthine, 2,6-diaminopurine, and 2-aminopurine nucleobases. | The Journal of organic chemistry 20040528 |
| LNA guanine and 2,6-diaminopurine. Synthesis, characterization and hybridization properties of LNA 2,6-diaminopurine containing oligonucleotides. | Bioorganic & medicinal chemistry 20040501 |
| Attempt to reduce cytotoxicity by synthesizing the L-enantiomer of 4'-C-ethynyl-2'-deoxypurine nucleosides as antiviral agents against HIV and HBV. | Antiviral chemistry & chemotherapy 20040501 |
| Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase. | RNA (New York, N.Y.) 20040301 |
| In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir? | Antiviral research 20040301 |
| Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides. | Journal of medicinal chemistry 20040129 |
| Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides. | Nucleosides, nucleotides & nucleic acids 20040101 |
| Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids. | Nucleosides, nucleotides & nucleic acids 20031201 |
| Cytostatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes. | Toxicology and applied pharmacology 20031101 |
| Substrate analogues for an RNA-editing adenosine deaminase: mechanistic investigation and inhibitor design. | Journal of the American Chemical Society 20030910 |
| Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N6-substituted adenines, and 2,6-diaminopurines. | European journal of pharmacology 20030815 |
| 3-Bromopyrazolo[3,4-d]pyrimidine 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides: modified DNA constituents with an unusually rigid sugar N-conformation. | The Journal of organic chemistry 20030711 |
| 2,6-Diamino-5,8-diaza-7,9-dicarba-purine. | Organic letters 20030612 |
| C-Nucleosidations with 2,6-diamino-5,8-diaza-7,9-dicarba-purine. | Organic letters 20030612 |
| Synthesis of (Z)-(2,3-bis-hydroxymethyl)methylenecyclopropane analogues of purine nucleosides. | Nucleosides, nucleotides & nucleic acids 20030301 |
| Thermodynamic coupling of the loop and stem in unusually stable DNA hairpins closed by CG base pairs. | Journal of the American Chemical Society 20030226 |
| The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. | BMC biochemistry 20030101 |
| Synthesis and antiviral activity of a series of new cyclohexenyl nucleosides. | Antiviral chemistry & chemotherapy 20030101 |
| Chemo-enzymatic synthesis of 3-deoxy-beta-D-ribofuranosyl purines and study of their biological properties. | Nucleosides, nucleotides & nucleic acids 20030101 |
| Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with multisubstrate analogue inhibitor with 2,6-diaminopurine aglycone. | Nucleosides, nucleotides & nucleic acids 20030101 |
| A ribozyme composed of only two different nucleotides. | Nature 20021201 |
| 5-propynyluracil.diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA. | Chemical communications (Cambridge, England) 20020807 |
| DNA sequence recognition by the antitumor drug ditercalinium. | Biochemistry 20020709 |
| 2,6-diaminopurine in TNA: effect on duplex stabilities and on the efficiency of template-controlled ligations. | Organic letters 20020418 |
| Structure-activity relationships of 2'-fluoro-2',3'-unsaturated D-nucleosides as anti-HIV-1 agents. | Journal of medicinal chemistry 20020314 |
| Novel antagonists acting at the P2Y(1) purinergic receptor: synthesis and conformational analysis using potentiometric and nuclear magnetic resonance titration techniques. | Journal of medicinal chemistry 20020214 |
| Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios. | BMC biotechnology 20020101 |
| Diaminopurine-acridine heterodimers for specific recognition of abasic site containing DNA. Influence on the biological activity of the position of the linker on the purine ring. | Bioorganic & medicinal chemistry letters 20010723 |
| Hamster and rat fetal cells have low spontaneous mutation frequencies and rates. | Mutation research 20010701 |
| Potentiation of BCNU cytotoxicity by molecules targeting abasic lesions in DNA. | Bioorganic & medicinal chemistry 20010701 |
| Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme. | Biochemistry 20010220 |
| Photolithographic synthesis of high-density oligonucleotide arrays. | Methods in molecular biology (Clifton, N.J.) 20010101 |
| Antitumour activity of N6-substituted PMEDAP derivatives against T-cell lymphoma. | Anticancer research 20010101 |
| Mechanism of action and in vitro activity of 1',3'-dioxolanylpurine nucleoside analogues against sensitive and drug-resistant human immunodeficiency virus type 1 variants. | Antimicrobial agents and chemotherapy 19991001 |
| Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. | Biochemical pharmacology 19951109 |
| (+-)-carbocyclic 5'-nor-2'-deoxyguanosine and related purine derivatives: synthesis and antiviral properties. | Journal of medicinal chemistry 19920612 |