Home Sulfos Benzenesulfonic acid, 2,5-dihydroxy-, calcium salt (2:1)

Benzenesulfonic acid, 2,5-dihydroxy-, calcium salt (2:1)

CAS No.:
20123-80-2
Catalog Number:
AG002DAR
Molecular Formula:
C12H10CaO10S2
Molecular Weight:
418.4098
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
98%(HPLC)
In Stock USA
United States
$103
- +
1g
98%(HPLC)
In Stock USA
United States
$266
- +
5g
98%(HPLC)
In Stock USA
United States
$1008
- +
Product Description
Catalog Number:
AG002DAR
Chemical Name:
Benzenesulfonic acid, 2,5-dihydroxy-, calcium salt (2:1)
CAS Number:
20123-80-2
Molecular Formula:
C12H10CaO10S2
Molecular Weight:
418.4098
MDL Number:
MFCD08457542
IUPAC Name:
calcium;2,5-dihydroxybenzenesulfonate
InChI:
InChI=1S/2C6H6O5S.Ca/c2*7-4-1-2-5(8)6(3-4)12(9,10)11;/h2*1-3,7-8H,(H,9,10,11);/q;;+2/p-2
InChI Key:
QGNBTYAQAPLTMX-UHFFFAOYSA-L
SMILES:
Oc1ccc(c(c1)S(=O)(=O)[O-])O.Oc1ccc(c(c1)S(=O)(=O)[O-])O.[Ca+2]
EC Number:
243-531-5
UNII:
5921X1560Q
Properties
Complexity:
228  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
417.934g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
418.4g/mol
Monoisotopic Mass:
417.934g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
212A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Phlebotonics for haemorrhoids. The Cochrane database of systematic reviews 20120815
Treatment of dry age-related macular degeneration with dobesilate. BMJ case reports 20120101
Short-term efficacy of intravitreal dobesilate in central serous chorioretinopathy. European journal of medical research 20120101
Calcium dobesilate may improve hemorheology in patients undergoing coronary artery bypass grafting. Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular 20120101
Treatment of Stargardt disease with dobesilate. BMJ case reports 20120101
In vitro effect of calcium dobesilate on oxidative/inflammatory stress in human varicose veins. Phlebology 20111201
Modulation of the intramedullary pressure responses by calcium dobesilate in a rabbit knee model of osteoarthritis. Acta orthopaedica 20111001
Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate. European journal of pharmacology 20110930
Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate. British journal of cancer 20101026
Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes. Diabetes 20101001
Pharmacological treatment in patients with C4, C5 and C6 venous disease. Phlebology 20101001
Evaluation of calcium dobesilate for its anti-cataract potential in experimental animal models. Methods and findings in experimental and clinical pharmacology 20100401
Calcium dobesilate reduces oxidative stress in cardiac surgery. The Journal of cardiovascular surgery 20091001
Prevention of diabetic retinopathy. Lancet (London, England) 20090418
Effect of calcium dobesilate on occurrence of diabetic macular oedema (CALDIRET study): randomised, double-blind, placebo-controlled, multicentre trial. Lancet (London, England) 20090418
[Protective effect of calcium dobesilate against early diabetic nephropathy of rat kidney]. Yao xue xue bao = Acta pharmaceutica Sinica 20090201
Reduced intimal hyperplasia in rabbits via medical therapy after carotid venous bypass. Texas Heart Institute journal 20090101
Effects of calcium dobesilate and diosmin-hesperidin on apoptosis of venous wall in primary varicose veins. VASA. Zeitschrift fur Gefasskrankheiten 20080801
An electrochemical sensor for determination of calcium dobesilate based on PoPD/MWNTs composite film modified glassy carbon electrode. Journal of biochemical and biophysical methods 20080424
Effect of calcium dobesilate on progression of early diabetic retinopathy: a randomised double-blind study. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20061201
Attenuation of acute lung injury following lower limb ischemia/reperfusion: the pharmacological approach. The Journal of cardiovascular surgery 20060801
Cardioprotective effect of calcium dobesilate during open-heart surgery. Acta cardiologica 20060201
The effects of clopidogrel and calcium dobesilate on intimal hyperplasia following vascular injury. Acta chirurgica Belgica 20060101
Dihydroxy-2,5 benzenesulphonate (dobesilate) elicits growth arrest and apoptosis in glioma cells. Neurological research 20051201
Validation of liquid chromatographic method for analysis of lidocaine hydrochloride, dexamethasone acetate, calcium dobesilate, buthylhydroxyanisol and degradation product hydroquinone in suppositories and ointment. Journal of chromatography. A 20050923
Phlebotonics for venous insufficiency. The Cochrane database of systematic reviews 20050720
Calcium dobesilate attenuates vascular injury and the progression of diabetic retinopathy in streptozotocin-induced diabetic rats. Diabetes/metabolism research and reviews 20050101
Effect of calcium dobesilate on nephropathy in type 2 diabetic rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101
Drug treatment of haemorrhoids. Drugs 20050101
Effects of calcium dobesilate on glomerulus TIMP1 and collagen IV of diabetic rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101
Efficacy of troxerutin on streptozotocin-induced rat model in the early stage of diabetic retinopathy. Arzneimittel-Forschung 20050101
Flow injection chemiluninescence for detecting picogram amounts of dobesilate in human urine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040801
Reduction of retinal albumin leakage by the antioxidant calcium dobesilate in streptozotocin-diabetic rats. European journal of pharmacology 20040714
Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF. Biochemical and biophysical research communications 20031226
The effect of calcium dobesilate on vascular endothelial function, blood pressure, and markers of oxidation in obese male smokers: a placebo-controlled randomised clinical trial. Atherosclerosis 20030901
Calcium dobesilate potentiates endothelium-derived hyperpolarizing factor-mediated relaxation of human penile resistance arteries. British journal of pharmacology 20030601
Calcium dobesilate ameliorates lung injury following lower limb ischemia/reperfusion. Drugs under experimental and clinical research 20020101
Antioxidant properties of calcium dobesilate in ischemic/reperfused diabetic rat retina. European journal of pharmacology 20011005
Determination of calcium dobesilate in human plasma using ion-pairing extraction and high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications 20010505
Properties