Home Sulfos Benzenesulfonamide, 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]-

Benzenesulfonamide, 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]-

CAS No.:
200933-14-8
Catalog Number:
AG002D2O
Molecular Formula:
C16H16F3NO2S
Molecular Weight:
343.3639
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥95%
1 week
United States
$111
- +
10mg
≥95%
1 week
United States
$160
- +
25mg
≥95%
1 week
United States
$287
- +
50mg
≥95%
1 week
United States
$490
- +
Product Description
Catalog Number:
AG002D2O
Chemical Name:
Benzenesulfonamide, 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]-
CAS Number:
200933-14-8
Molecular Formula:
C16H16F3NO2S
Molecular Weight:
343.3639
MDL Number:
MFCD00095824
IUPAC Name:
2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
InChI:
InChI=1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3
InChI Key:
ZIIUUSVHCHPIQD-UHFFFAOYSA-N
SMILES:
Cc1cc(C)c(c(c1)C)S(=O)(=O)Nc1cccc(c1)C(F)(F)F
Properties
Complexity:
488  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
343.085g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
343.364g/mol
Monoisotopic Mass:
343.085g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
54.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.4  
Literature
Title Journal
Effects of heparin and related drugs on neutrophil function. Pulmonary pharmacology & therapeutics 20120401
Effect of m-3m3FBS on Ca2+ handling and viability in OC2 human oral cancer cells. Acta physiologica Hungarica 20120301
Mechanisms underlying impairment of endothelium-dependent relaxation by fetal bovine serum in organ-cultured rat mesenteric artery. European journal of pharmacology 20111015
Effect of m-3M3FBS on Ca²⁺ movement in PC3 human prostate cancer cells. The Chinese journal of physiology 20100630
Phospholipase C-independent effects of 3M3FBS in murine colon. European journal of pharmacology 20100225
Effect of m-3M3FBS on Ca(2+) movement in Madin-Darby canine renal tubular cells. Human & experimental toxicology 20091001
Wnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090506
Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081105
Phospholipase C beta3 is a key component in the Gbetagamma/PKCeta/PKD-mediated regulation of trans-Golgi network to plasma membrane transport. The Biochemical journal 20070815
Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways. Journal of cellular biochemistry 20060201
3-O-acetyl-11-keto-boswellic acid decreases basal intracellular Ca2+ levels and inhibits agonist-induced Ca2+ mobilization and mitogen-activated protein kinase activation in human monocytic cells. The Journal of pharmacology and experimental therapeutics 20060101
Effects of a new isoquinolinone derivative on induction of action potential bursts in central snail neuron. Pharmacology 20051001
The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis. Cancer letters 20050526
Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. British journal of pharmacology 20040901
Phospholipase C activator 2,4,6-trimethyl-N-(meta-3-trifluoromethyl-phenyl)-benzene-sulfonamide decays under ultraviolet light and shows strong self-fluorescence. Analytical biochemistry 20040715
Identification of a compound that directly stimulates phospholipase C activity. Molecular pharmacology 20030501
Properties