6-Thioxo-6,9-dihydro-1h-purin-2(3h)-one
| Title | Journal |
|---|---|
| Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II). | Toxicology and applied pharmacology 20180620 |
| Two brothers with skewed thiopurine metabolism in ulcerative colitis treated successfully with allopurinol and mercaptopurine dose reduction. | Digestive diseases and sciences 20120101 |
| Infected dendritic cells facilitate systemic dissemination and transplacental passage of the obligate intracellular parasite Neospora caninum in mice. | PloS one 20120101 |
| Deficiency of a Niemann-Pick, type C1-related protein in toxoplasma is associated with multiple lipidoses and increased pathogenicity. | PLoS pathogens 20111201 |
| The role of transmembrane segment TM3 in the xanthine permease XanQ of Escherichia coli. | The Journal of biological chemistry 20111111 |
| The motility of a human parasite, Toxoplasma gondii, is regulated by a novel lysine methyltransferase. | PLoS pathogens 20110901 |
| Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control. | PLoS pathogens 20110901 |
| The moving junction protein RON8 facilitates firm attachment and host cell invasion in Toxoplasma gondii. | PLoS pathogens 20110301 |
| Involvement of a Toxoplasma gondii chromatin remodeling complex ortholog in developmental regulation. | PloS one 20110101 |
| Cysteine-scanning analysis of helices TM8, TM9a, and TM9b and intervening loops in the YgfO xanthine permease: a carboxyl group is essential at ASP-276. | The Journal of biological chemistry 20101105 |
| A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division. | PLoS pathogens 20100901 |
| Purine substrate recognition by the nucleobase-ascorbate transporter signature motif in the YgfO xanthine permease: ASN-325 binds and ALA-323 senses substrate. | The Journal of biological chemistry 20100618 |
| TgMORN1 is a key organizer for the basal complex of Toxoplasma gondii. | PLoS pathogens 20100201 |
| Kinetics of 6-thioxanthine metabolism by allelic variants of xanthine oxidase. | Drug metabolism and pharmacokinetics 20100101 |
| Cysteine-scanning analysis of putative helix XII in the YgfO xanthine permease: ILE-432 and ASN-430 are important. | The Journal of biological chemistry 20080516 |
| Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii. | PLoS pathogens 20080201 |
| In vitro study of 6-mercaptopurine oxidation catalysed by aldehyde oxidase and xanthine oxidase. | Drug metabolism and pharmacokinetics 20070801 |
| Nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase--enzymatic reaction pathways of 6-mercaptopurine and 2-mercaptopurine are different. | Biochemistry. Biokhimiia 20070201 |
| Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol. | BMC biochemistry 20070101 |
| Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases. | Journal of medicinal chemistry 20061214 |
| Biochemical and pharmacological properties of an allosteric modulator site of the human P-glycoprotein (ABCB1). | Biochemical pharmacology 20060714 |
| Inhibition of MHC class I is a virulence factor in herpes simplex virus infection of mice. | PLoS pathogens 20050901 |
| Determination of mercaptopurine and its four metabolites by large-volume sample stacking with polarity switching in capillary electrophoresis. | Electrophoresis 20050601 |
| Inhibition of DNA repair glycosylases by base analogs and tryptophan pyrolysate, Trp-P-1. | Acta biochimica Polonica 20050101 |
| [Dementia induced by antipsychotic drugs]. | Nihon rinsho. Japanese journal of clinical medicine 20040101 |
| Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems. | European journal of biochemistry 20020801 |
| Current progress in suicide gene therapy for cancer. | World journal of surgery 20020701 |
| Suicide gene transduction sensitizes murine embryonic and human mesenchymal stem cells to ablation on demand-- a fail-safe protection against cellular misbehavior. | Gene therapy 20020701 |
| Identification and characterization of differentiation mutants in the protozoan parasite Toxoplasma gondii. | Molecular microbiology 20020501 |
| Toxoplasma gondii: mechanism of the parasitostatic action of 6-thioxanthine. | Experimental parasitology 20011201 |
| Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. | Biochemical pharmacology 19951109 |