Home Other Building Blocks ethyl 3-(4-fluorophenyl)-3-oxopropanoate

ethyl 3-(4-fluorophenyl)-3-oxopropanoate

CAS No.:
1999-00-4
Catalog Number:
AG002CFK
Molecular Formula:
C11H11FO3
Molecular Weight:
210.2016
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
97%
In Stock USA
United States
$15
- +
5g
97%
In Stock USA
United States
$50
- +
25g
97%
In Stock USA
United States
$200
- +
100g
97%
In Stock USA
United States
$663
- +
Product Description
Catalog Number:
AG002CFK
Chemical Name:
ethyl 3-(4-fluorophenyl)-3-oxopropanoate
CAS Number:
1999-00-4
Molecular Formula:
C11H11FO3
Molecular Weight:
210.2016
MDL Number:
MFCD03093631
IUPAC Name:
ethyl 3-(4-fluorophenyl)-3-oxopropanoate
InChI:
InChI=1S/C11H11FO3/c1-2-15-11(14)7-10(13)8-3-5-9(12)6-4-8/h3-6H,2,7H2,1H3
InChI Key:
SJUXLKYJKQBZLM-UHFFFAOYSA-N
SMILES:
CCOC(=O)CC(=O)c1ccc(cc1)F
EC Number:
606-415-9
Properties
Complexity:
232  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
210.069g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
210.204g/mol
Monoisotopic Mass:
210.069g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
43.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2  
Literature
Title Journal
Genital ulcer disease treatment for reducing sexual acquisition of HIV. The Cochrane database of systematic reviews 20120815
Mass spectrometic study of speciation in aluminium-fluoroquinolone solutions. European journal of mass spectrometry (Chichester, England) 20120101
Air- and heat-stable planar tri-p-quinodimethane with distinct biradical characteristics. Journal of the American Chemical Society 20111019
Photodegradation of fleroxacin injection: different products with different concentration levels. AAPS PharmSciTech 20110901
Synergistic antitumor effects of fleroxacin with 5-fluorouracil in vitro and in vivo for bladder cancer cell lines. Urology 20091201
Inter- and intramolecular photochemical reactions of fleroxacin. Organic letters 20090507
Enhanced separation of seven quinolones by capillary electrophoresis with silica nanoparticles as additive. Talanta 20090315
Capillary electrophoresis with electrochemiluminescence detection for simultaneous determination of proline and fleroxacin in human urine. Drug testing and analysis 20090201
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents. Drug metabolism and pharmacokinetics 20090101
A rapid CE-potential gradient detection method for determination of quinolones. Electrophoresis 20071101
1H and 19F NMR relaxation studies of fleroxacin with Micrococcus luteus. Journal of pharmaceutical and biomedical analysis 20070411
[Study on the ternary complex of FLRX, zinc(II) and BSA by the method of fluorescence]. Guang pu xue yu guang pu fen xi = Guang pu 20070401
[Clinical observation on shufei granule in improving right ventricular function of patients with chronic pulmonary heart disease]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060801
[Determination of fleroxacin by photochemical fluorescence of zinc-fleroxacin complex]. Guang pu xue yu guang pu fen xi = Guang pu 20050901
Synthesis and antibacterial activity of 1-(2-fluorovinyl)-7-substituted-4-quinolone-3-carboxylic acid derivatives, conformationally restricted analogues of fleroxacin. Journal of medicinal chemistry 20050505
[Ultraviolet spectral characteristics of charge-transfer reaction complex in micellar system and its application]. Guang pu xue yu guang pu fen xi = Guang pu 20050201
A randomized clinical trial to compare fleroxacin-rifampicin with flucloxacillin or vancomycin for the treatment of staphylococcal infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041101
Validation of an HPLC method for the determination of fleroxacin and its photo-degradation products in pharmaceutical forms. Annali di chimica 20040101
[Fluorescence spectrometric determination of fleroxacin by charge-transfer reaction]. Guang pu xue yu guang pu fen xi = Guang pu 20030401
Inhibition by fluoroquinolones of K(+) currents in rat dissociated hippocampal neurons. European journal of pharmacology 20030221
Determination of fleroxacin in pure and tablet forms by liquid chromatography and derivative UV-spectrophotometry. Journal of AOAC International 20030101
Influence of sex on the pharmacokinetic interaction of fleroxacin and ciprofloxacin with caffeine. Clinical pharmacokinetics 20030101
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone]. The Japanese journal of antibiotics 20021201
A pilot study of oral fleroxacin once daily compared with conventional therapy in patients with pyogenic liver abscess. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20020901
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration]. The Japanese journal of antibiotics 20020601
Protective effect of fleroxacin against the nephrotoxicity of isepamicin in rats. Biological & pharmaceutical bulletin 20020401
Ultrastructure of Achilles tendon from rats after treatment with fleroxacin. Archives of toxicology 20010401
Effects of fluoroquinolones on the locomotor activity in rats. Archives of toxicology 20010301
Spectrophotometric and HPLC determination of fleroxacin in tablets. Die Pharmazie 20010201
Fleroxacin uptake in ischaemic limb tissue. Acta microbiologica et immunologica Hungarica 20010101
[Encephalopathy induced by fleroxacin in a patient with Machado-Joseph disease]. Rinsho shinkeigaku = Clinical neurology 19980901
Atypical pneumonia in the Nordic countries: aetiology and clinical results of a trial comparing fleroxacin and doxycycline. Nordic Atypical Pneumonia Study Group. The Journal of antimicrobial chemotherapy 19970401
Fleroxacin 400 mg once daily versus ofloxacin 400 mg twice daily in skin and soft tissue infections. Chemotherapy 19970101
Two cases of fleroxacin-induced insomnia. International clinical psychopharmacology 19940101
Activity of topoisomerase inhibitors against Pneumocystis carinii in vitro and in an inoculated mouse model. Antimicrobial agents and chemotherapy 19930701
Comparative in vitro and in vivo activity of fleroxacin and ofloxacin against various mycobacteria. Tubercle 19910901
Central nervous system toxicity of quinolones: human and animal findings. The Journal of antimicrobial chemotherapy 19901001
The antimicrobial activity of Fleroxacin RO 23-6240, a third generation fluoroquinolone derivative, tested in vitro. Journal of hygiene, epidemiology, microbiology, and immunology 19900101
Adverse reactions in a dose-ranging study with a new long-acting fluoroquinolone, fleroxacin. Antimicrobial agents and chemotherapy 19891001
Comparative in-vitro activity of fleroxacin and other 6-fluoroquinolones against mycobacteria. The Journal of antimicrobial chemotherapy 19881001
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