1,3-Dimethyl-5-adamantanamine
Title | Journal |
---|---|
Memantine can improve chronic ethanol exposure-induced spatial memory impairment in male C57BL/6 mice by reducing hippocampal apoptosis. | Toxicology 20180801 |
Zebrafish is a predictive model for identifying compounds that protect against brain toxicity in severe acute organophosphorus intoxication. | Archives of toxicology 20170101 |
Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies. | Neurotoxicology 20160501 |
Glial activation and post-synaptic neurotoxicity: the key events in Streptozotocin (ICV) induced memory impairment in rats. | Pharmacology, biochemistry, and behavior 20140201 |
Memantine in patients with moderate to severe Alzheimer's disease: meta-analyses using realistic definitions of response. | Dementia and geriatric cognitive disorders 20140101 |
Xanthoceraside attenuates learning and memory deficits via improving insulin signaling in STZ-induced AD rats. | Neuroscience letters 20130524 |
Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B. | Journal of medicinal chemistry 20121108 |
Using an experimental medicine model to understand the antidepressant potential of the N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine. | Journal of psychopharmacology (Oxford, England) 20121101 |
Pharmacological prevention and treatment of vascular dementia: approaches and perspectives. | Experimental gerontology 20121101 |
Effect of intratympanic dexamethasone, memantine and piracetam on cellular apoptosis due to cisplatin ototoxicity. | The Journal of laryngology and otology 20121101 |
Pharmacological treatment of dementia. | Current opinion in psychiatry 20121101 |
Enantiomerically pure 1,3-dioxanes as highly selective NMDA and σ₁ receptor ligands. | Journal of medicinal chemistry 20121025 |
Cutaneous analgesia after subcutaneous injection of memantine and amantadine and their systemic toxicity in rats. | European journal of pharmacology 20121015 |
Memantine prevents cognitive impairment and reduces Bcl-2 and caspase 8 immunoreactivity in rats injected with amyloid β1-40. | European journal of pharmacology 20121005 |
Preliminary studies of (99m)Tc-memantine derivatives for NMDA receptor imaging. | Nuclear medicine and biology 20121001 |
Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice. | Neurobiology of disease 20121001 |
Age-dependent therapeutic effect of memantine in a mouse model of juvenile Batten disease. | Neuropharmacology 20121001 |
Underrecognition and undertreatment of dementia in Italian nursing homes. | Journal of the American Medical Directors Association 20121001 |
Clinical trials of dementia with Lewy bodies and Parkinson's disease dementia. | Current neurology and neuroscience reports 20121001 |
Memantine improves safety of thrombolysis for stroke. | Stroke 20121001 |
Racial and ethnic disparities in Alzheimer's disease pharmacotherapy exposure: an analysis across four state Medicaid populations. | The American journal of geriatric pharmacotherapy 20121001 |
A novel hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonist prevents ischemic neuronal death. | The Journal of biological chemistry 20120914 |
Okadaic acid induced neurotoxicity leads to central cholinergic dysfunction in rats. | European journal of pharmacology 20120905 |
Memantine for late-life depression and apathy after a disabling medical event: a 12-week, double-blind placebo-controlled pilot study. | International journal of geriatric psychiatry 20120901 |
Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine--searching for the connections. | British journal of pharmacology 20120901 |
Use of drug treatments for Alzheimer's disease in France: a study on a national level based on the National Alzheimer's Data Bank (Banque Nationale Alzheimer). | Pharmacoepidemiology and drug safety 20120901 |
Transdermal absorption of memantin--effect of chemical enhancers, iontophoresis, and role of enhancer lipophilicity. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120901 |
Subgroup analysis of US and non-US patients in a global study of high-dose donepezil (23 mg) in moderate and severe Alzheimer's disease. | American journal of Alzheimer's disease and other dementias 20120901 |
Effectiveness of the combination of memantine plus vitamin D on cognition in patients with Alzheimer disease: a pre-post pilot study. | Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20120901 |
A review of the effects of memantine on clinical progression in Alzheimer's disease. | International journal of geriatric psychiatry 20120801 |
Depressive-like behavior in adrenocorticotropic hormone-treated rats blocked by memantine. | Pharmacology, biochemistry, and behavior 20120801 |
Neuroprotective and neurogenesis agent for treating bipolar II disorder: add-on memantine to mood stabilizer works. | Medical hypotheses 20120801 |
The role of memantine in the treatment of psychiatric disorders other than the dementias: a review of current preclinical and clinical evidence. | CNS drugs 20120801 |
Open-channel blockade is less effective on GluN3B than GluN3A subunit-containing NMDA receptors. | European journal of pharmacology 20120705 |
N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's disease. | Current Alzheimer research 20120701 |
Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism. | Psychopharmacology 20120701 |
Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. | Archives of neurology 20120701 |
False recognition in a mouse model of Alzheimer's disease: rescue with sensory restriction and memantine. | Brain : a journal of neurology 20120701 |
Antagonism of NMDA receptors as a potential treatment for Down syndrome: a pilot randomized controlled trial. | Translational psychiatry 20120701 |
Glutamatergic approaches in major depressive disorder: focus on ketamine, memantine and riluzole. | Drugs of today (Barcelona, Spain : 1998) 20120701 |
[Effects of ionotropic glutamate receptor channel blockers ON sleep-waking organization in rats]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120701 |
Working memory in the aged Ts65Dn mouse, a model for Down syndrome. | Behavioural brain research 20120615 |
Discontinuing donepezil or starting memantine for Alzheimer's disease. | The New England journal of medicine 20120607 |
Discontinuing donepezil or starting memantine for Alzheimer's disease. | The New England journal of medicine 20120607 |
Cost-effectiveness of memantine in moderate and severe Alzheimer's disease in Norway. | International journal of geriatric psychiatry 20120601 |
The pharmacological sensitivity of a touchscreen-based visual discrimination task in the rat using simple and perceptually challenging stimuli. | Psychopharmacology 20120601 |
Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat. | British journal of pharmacology 20120601 |
Memantine for axonal loss of optic neuritis. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120601 |
Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats. | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120601 |
Memantine potentiates hippocampal θ oscillations at a therapeutic dose in anesthetized mice: a mechanistic link to its cognitive-enhancing properties. | Neuropharmacology 20120601 |
Memantine treatment reverses anhedonia, normalizes corticosterone levels and increases BDNF levels in the prefrontal cortex induced by chronic mild stress in rats. | Metabolic brain disease 20120601 |
Modulation of histone deacetylase attenuates naloxone-precipitated opioid withdrawal syndrome. | Naunyn-Schmiedeberg's archives of pharmacology 20120601 |
Efficacy of memantine in delaying clinical worsening in Alzheimer's disease (AD): responder analyses of nine clinical trials with patients with moderate to severe AD. | International journal of geriatric psychiatry 20120601 |
Is delay of clinical worsening a valuable goal in the treatment of Alzheimer's disease? | International journal of geriatric psychiatry 20120601 |
Use of antidementia drugs in frontotemporal lobar degeneration. | American journal of Alzheimer's disease and other dementias 20120601 |
The pharmacological treatment of acquired nystagmus. | Practical neurology 20120601 |
Alzheimer's disease: early diagnosis and treatment. | Hong Kong medical journal = Xianggang yi xue za zhi 20120601 |
Combination therapy no advantage in Alzheimer's treatment. | Harvard health letter 20120601 |
Drugs for Alzheimer's disease: best avoided. No therapeutic advantage. | Prescrire international 20120601 |
A study on neuroinflammatory marker in brain areas of okadaic acid (ICV) induced memory impaired rats. | Life sciences 20120522 |
Protection from glutamate-induced excitotoxicity by memantine. | Annals of biomedical engineering 20120501 |
Effects of Food and Drug Administration-approved medications for Alzheimer's disease on clinical progression. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20120501 |
Simultaneous determination of antidementia drugs in human plasma: procedure transfer from HPLC-MS to UPLC-MS/MS. | Journal of pharmaceutical and biomedical analysis 20120501 |
Memantine facilitates memory consolidation and reconsolidation in the day-old chick. | Neurobiology of learning and memory 20120501 |
Tracking cognitive change over 24 weeks with longitudinal functional magnetic resonance imaging in Alzheimer's disease. | Neuro-degenerative diseases 20120501 |
Cholinesterase inhibitors and memantine for symptomatic treatment of dementia. | BMJ (Clinical research ed.) 20120501 |
Open-label pilot study of memantine in the treatment of compulsive buying. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20120501 |
Economic evaluation of treatment options in patients with Alzheimer's disease: a systematic review of cost-effectiveness analyses. | Drugs 20120416 |
Administration of memantine and imipramine alters mitochondrial respiratory chain and creatine kinase activities in rat brain. | Journal of neural transmission (Vienna, Austria : 1996) 20120401 |
Antitussive effects of memantine in guinea pigs. | Chest 20120401 |
New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs. | British journal of clinical pharmacology 20120401 |
Memantine partly rescues behavioral and cognitive deficits in an animal model of neurodegeneration. | Neuropharmacology 20120401 |
Cell proliferation in the hippocampus and in the heart is modified by exposure to repeated stress and treatment with memantine. | Journal of psychiatric research 20120401 |
Validity, significance, strengths, limitations, and evidentiary value of real-world clinical data for combination therapy in Alzheimer's disease: comparison of efficacy and effectiveness studies. | Neuro-degenerative diseases 20120401 |
Drugs for Alzheimer's disease. | British journal of clinical pharmacology 20120401 |
Structure/function studies and the effects of memantine in monkeys with experimental glaucoma. | Investigative ophthalmology & visual science 20120401 |
[Effects of ionotropic glutamate receptor channel blockers on the development of audiogenic seizures in Krushinski-Molodkina rats]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120401 |
Memantine in Alzheimer's disease: experience in an Alzheimer's disease assessment unit. | Aging clinical and experimental research 20120401 |
Alzheimer disease: Treatment of Alzheimer disease in Down syndrome. | Nature reviews. Neurology 20120313 |
Donepezil and memantine for moderate-to-severe Alzheimer's disease. | The New England journal of medicine 20120308 |
Discontinuing donepezil or starting memantine for Alzheimer's disease. | The New England journal of medicine 20120308 |
[Stimulant and non-stimulant medication in current and future therapy for ADHD]. | Fortschritte der Neurologie-Psychiatrie 20120301 |
Influence of memantine on nociceptive responses of the trigeminocervical complex after formalin injection. | Cephalalgia : an international journal of headache 20120301 |
Morphine and memantine treatment of long-standing complex regional pain syndrome. | Pain medicine (Malden, Mass.) 20120301 |
Symptomatic and nonamyloid/tau based pharmacologic treatment for Alzheimer disease. | Cold Spring Harbor perspectives in medicine 20120301 |
The 'blue' side of glutamatergic neurotransmission: NMDA receptor antagonists as possible novel therapeutics for major depression. | Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20120301 |
Memantine for dementia in adults older than 40 years with Down's syndrome (MEADOWS): a randomised, double-blind, placebo-controlled trial. | Lancet (London, England) 20120211 |
Improving Alzheimer's disease outcomes in Down's syndrome. | Lancet (London, England) 20120211 |
Memantine effects on behaviour in moderately severe to severe Alzheimer's disease: a post-marketing surveillance study. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120201 |
Determination of memantine in rat plasma by HPLC-fluorescence method and its application to study of the pharmacokinetic interaction between memantine and methazolamide. | Biomedical chromatography : BMC 20120201 |
Pharmacologic treatment of apathy in dementia. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20120201 |
Possibility of a new anti-alzheimer's disease pharmaceutical composition combining memantine and vitamin D. | Drugs & aging 20120201 |
Neuroprotective effects of minocycline on double-stranded RNA-induced neurotoxicity in cultured cortical neurons. | Hong Kong medical journal = Xianggang yi xue za zhi 20120201 |
Early antidepressant effect of memantine during augmentation of lamotrigine inadequate response in bipolar depression: a double-blind, randomized, placebo-controlled trial. | Bipolar disorders 20120201 |
[Intended pharmacotherapeutical approaches of Alzheimer's disease therapy]. | Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20120201 |
Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities. | Bioorganic & medicinal chemistry 20120115 |
Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo. | Neuroscience letters 20120111 |
Detecting treatment effects with combinations of the ADAS-cog items in patients with mild and moderate Alzheimer's disease. | International journal of geriatric psychiatry 20120101 |
Memantine and functional communication in Alzheimer's disease: results of a 12-week, international, randomized clinical trial. | Journal of Alzheimer's disease : JAD 20120101 |
Calpain activation is involved in acute manganese neurotoxicity in the rat striatum in vivo. | Experimental neurology 20120101 |
The sustained mood-stabilizing effect of memantine in the management of treatment resistant bipolar disorders: findings from a 12-month naturalistic trial. | Journal of affective disorders 20120101 |
The N-methyl-d-aspartic acid receptor antagonist memantine ameliorates and delays the development of arthritis by enhancing regulatory T cells. | Neuro-Signals 20120101 |
Differentiation of HT22 neurons induces expression of NMDA receptor that mediates homocysteine cytotoxicity. | Neurological research 20120101 |
Memantine and brain atrophy in Alzheimer's disease: a 1-year randomized controlled trial. | Journal of Alzheimer's disease : JAD 20120101 |
Evaluating the cost effectiveness of donepezil in the treatment of Alzheimer's disease in Germany using discrete event simulation. | BMC neurology 20120101 |
Effects of chronic memantine treatment on hippocampal extracellular glutamate and GABA levels during spatial alternation testing. | Georgian medical news 20120101 |
Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology. | International journal of molecular sciences 20120101 |
Synergistic effects of antidementia drugs on spatial learning and recall in the APP23 transgenic mouse model of Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20120101 |
Effects of memantine, an N-methyl-D-aspartate receptor antagonist, on fatigue and neuronal brain damage in a rat model of combined (physical and mental) fatigue. | Biological & pharmaceutical bulletin 20120101 |
Gantrez AN nanoparticles for ocular delivery of memantine: in vitro release evaluation in albino rabbits. | Ophthalmic research 20120101 |
The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): a systematic review and economic model. | Health technology assessment (Winchester, England) 20120101 |
Neuroprotective effect of noncompetitive NMDA receptor antagonists IEM-1957 and memantine in experimental focal cerebral ischemia. | Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20120101 |
Efficacy of memantine for agitation in Alzheimer's dementia: a randomised double-blind placebo controlled trial. | PloS one 20120101 |
Bioanalytical method development and validation of memantine in human plasma by high performance liquid chromatography with tandem mass spectrometry: application to bioequivalence study. | Journal of analytical methods in chemistry 20120101 |
[New anti-AD drugs--their possibilities and issues]. | Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20120101 |
Efficacy and safety of donepezil 23 mg versus donepezil 10 mg for moderate-to-severe Alzheimer's disease: a subgroup analysis in patients already taking or not taking concomitant memantine. | Dementia and geriatric cognitive disorders 20120101 |
The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome. | PloS one 20120101 |
A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI. | The journal of nutrition, health & aging 20120101 |
Radiation induces acute alterations in neuronal function. | PloS one 20120101 |
[Efficacy, safety and tolerability of a single dose of akatinol memantine in comparison to two-doses in patients with moderately expressed and moderately severe dementia in Alzheimer's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101 |
A study of potential pharmacokinetic and pharmacodynamic interactions between dextromethorphan/quinidine and memantine in healthy volunteers. | Clinical drug investigation 20120101 |
Memantine inhibits α3β2-nAChRs-mediated nitrergic neurogenic vasodilation in porcine basilar arteries. | PloS one 20120101 |
Effect of renal impairment on the pharmacokinetics of memantine. | Journal of pharmacological sciences 20120101 |
Simultaneous determination of Maillard reaction impurities in memantine tablets using HPLC with charged aerosol detector. | Journal of pharmaceutical and biomedical analysis 20111215 |
Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model. | Brain research 20111202 |
Direct costs of Alzheimer's disease in Germany. | The European journal of health economics : HEPAC : health economics in prevention and care 20111201 |
A placebo controlled trial of memantine as an adjunct to oral naltrexone for opioid dependence. | Drug and alcohol dependence 20111201 |
Memantine for posttraumatic stress disorder in an older veteran. | Journal of clinical psychopharmacology 20111201 |
Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine. | Learning & memory (Cold Spring Harbor, N.Y.) 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Management of moderate to severe Alzheimer's disease: focus on memantine. | Taiwanese journal of obstetrics & gynecology 20111201 |
Effects of the uncompetitive NMDA receptor antagonist memantine on spatial memory in medial septal lesioned rats. | Georgian medical news 20111201 |
[Antidotal effect of combinations obidoxime/HI-6 and memantine in mice poisoned with soman, dichlorvos or heptenophos]. | Vojnosanitetski pregled 20111201 |
[Memantine]. | Nihon rinsho. Japanese journal of clinical medicine 20111201 |
Memantine prevents aluminum-induced cognitive deficit in rats. | Behavioural brain research 20111120 |
ACP Journal Club. Review: cholinesterase inhibitors but not memantine increase syncope in older adults with mild cognitive impairment or dementia. | Annals of internal medicine 20111115 |
Patterns of dementia treatment use in assisted living facilities: a cross-sectional study of 1975 demented residents. | Journal of the American Medical Directors Association 20111101 |
The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20111101 |
Effects of memantine, a non-competitive N-methyl-D-aspartate receptor antagonist, on genomic stability. | Basic & clinical pharmacology & toxicology 20111101 |
On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down syndrome. | Developmental neuroscience 20111101 |
Does memantine improve the gait of individuals with Alzheimer's disease? | Journal of the American Geriatrics Society 20111101 |
Effective pharmacological management of Alzheimer's disease. | The American journal of managed care 20111101 |
The costs of Alzheimer's disease and the value of effective therapies. | The American journal of managed care 20111101 |
Pharmacologic treatment for memory disorder in multiple sclerosis. | The Cochrane database of systematic reviews 20111005 |
Memantine in systemic lupus erythematosus: a randomized, double-blind placebo-controlled trial. | Seminars in arthritis and rheumatism 20111001 |
Memantine for comorbid obsessive-compulsive disorder and Asperger disorder suggests a link in glutamatergic dysregulation. | Journal of clinical psychopharmacology 20111001 |
A new HPLC method with fluorescence detection for the determination of memantine in human plasma. | Journal of separation science 20111001 |
Use of memantine for the treatment of dementia. | Expert review of neurotherapeutics 20111001 |
Pharmacological treatment of Alzheimer disease. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20111001 |
Economic evaluation of the impact of memantine on time to nursing home admission in the treatment of Alzheimer disease. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20111001 |
The effect of memantine in harmaline-induced tremor and neurodegeneration. | Neuropharmacology 20110901 |
Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before. | Expert opinion on investigational drugs 20110901 |
Drug therapy of post-stroke aphasia: a review of current evidence. | Neuropsychology review 20110901 |
[Effects of glial cell line-derived neurotrophic factor and memantine on long-term prognosis in neonatal rats with periventricular leukomalacia]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110901 |
Pharmacological tests of hypotheses for acquired pendular nystagmus. | Annals of the New York Academy of Sciences 20110901 |
Memantine reduces mania-like symptoms in animal models. | Psychiatry research 20110815 |
Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome. | Behavioural brain research 20110810 |
The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine. | Behavioural brain research 20110810 |
Determining the minimum clinically important differences for outcomes in the DOMINO trial. | International journal of geriatric psychiatry 20110801 |
Clinical practice with anti-dementia drugs: a revised (second) consensus statement from the British Association for Psychopharmacology. | Journal of psychopharmacology (Oxford, England) 20110801 |
Alzheimer's disease and age-related memory decline (preclinical). | Pharmacology, biochemistry, and behavior 20110801 |
Memantine in moderate to severe Alzheimer's disease: an observational post-marketing study. | Journal of neural transmission (Vienna, Austria : 1996) 20110801 |
Memantine attenuates the impairment of spatial learning and memory of pentylenetetrazol-kindled rats. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110801 |
Lack of evidence for the efficacy of memantine in mild Alzheimer disease. | Archives of neurology 20110801 |
[Newly approved drugs for Alzheimer disease: effectiveness and limitation]. | Brain and nerve = Shinkei kenkyu no shinpo 20110801 |
New drugs for Alzheimer's disease in Japan. | Psychiatry and clinical neurosciences 20110801 |
Dementia with cardiac problems. | BMJ (Clinical research ed.) 20110722 |
Drugs: a tangled web of targets. | Nature 20110713 |
Antidementia drug prescription sources and patterns after the diagnosis of dementia in Germany: results of a claims data-based 1-year follow-up. | International clinical psychopharmacology 20110701 |
[Daily functioning in dementia: pharmacological and non-pharmacological interventions demonstrate small effects on heterogeneous scales]. | Psychiatrische Praxis 20110701 |
[Prescription differences of dementia drugs in urban and rural areas in Germany]. | Psychiatrische Praxis 20110701 |
The local anesthetic effect of memantine on infiltrative cutaneous analgesia in the rat. | Anesthesia and analgesia 20110701 |
Tolerability and efficacy of memantine add-on therapy to rivastigmine transdermal patches in mild to moderate Alzheimer's disease: a multicenter, randomized, open-label, parallel-group study. | Current medical research and opinion 20110701 |
Magnetic resonance imaging and neuropsychological results from a trial of memantine in Alzheimer's disease. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20110701 |
Cholinesterase inhibitor and memantine use in newly admitted nursing home residents with dementia. | Journal of the American Geriatrics Society 20110701 |
Combination therapy for Alzheimer's disease. | Drugs & aging 20110701 |
Memantine and catatonia: a case report and literature review. | Journal of psychiatric practice 20110701 |
AMPA workshop on challenges faced by investigators conducting Alzheimer's disease clinical trials. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20110701 |
Memantine abolishes the formation of cocaine-induced conditioned place preference possibly via its IL-6-modulating effect in medial prefrontal cortex. | Behavioural brain research 20110620 |
Treatment of Alzheimer disease. | American family physician 20110615 |
S 18986 reverses spatial working memory impairments in aged mice: comparison with memantine. | Psychopharmacology 20110601 |
Comparative protective action of curcumin, memantine and diclofenac against scopolamine-induced memory dysfunction. | Fitoterapia 20110601 |
Peripheral administration of NR2 antagonists attenuates orofacial formalin-induced nociceptive behavior in rats. | Progress in neuro-psychopharmacology & biological psychiatry 20110601 |
Dementia medications and risk of falls, syncope, and related adverse events: meta-analysis of randomized controlled trials. | Journal of the American Geriatrics Society 20110601 |
Possible antidepressant effects and mechanisms of memantine in behaviors and synaptic plasticity of a depression rat model. | Neuroscience 20110519 |
Subchronic memantine administration on spatial learning, exploratory activity, and nest-building in an APP/PS1 mouse model of Alzheimer's disease. | Neuropharmacology 20110501 |
Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices. | Neuropharmacology 20110501 |
Changes in nursing burden following memantine for agitation and aggression in long-term care residents with moderate to severe Alzheimer's disease: an open-label pilot study. | CNS drugs 20110501 |
Diagnosis of Alzheimer's disease patients with rapid cognitive decline in clinical practice: interest of the Deco questionnaire. | The journal of nutrition, health & aging 20110501 |
Alternative drug therapies for dementia. | Journal of psychosocial nursing and mental health services 20110501 |
Managing the patient with dementia in long-term care. | Clinics in geriatric medicine 20110501 |
Abhorring the vacuum: use of Alzheimer’s disease medications in frontotemporal dementia. | Expert review of neurotherapeutics 20110501 |
Synaptic plasticity deficits in an experimental model of rett syndrome: long-term potentiation saturation and its pharmacological reversal. | Neuroscience 20110428 |
Protection against Aβ-mediated rapid disruption of synaptic plasticity and memory by memantine. | Neurobiology of aging 20110401 |
Memantine in dementia: a review of the current evidence. | Expert opinion on pharmacotherapy 20110401 |
Serotonin transporter polymorphism as a predictor for escitalopram treatment of major depressive disorder comorbid with alcohol dependence. | Psychiatry research 20110330 |
Pharmacologic amelioration of severe hypoglycemia-induced neuronal damage. | Neuroscience letters 20110329 |
Pharmacological characterizations of memantine-induced disruption of prepulse inhibition of the acoustic startle response in mice: involvement of dopamine D2 and 5-HT2A receptors. | Behavioural brain research 20110317 |
AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure. | The Biochemical journal 20110315 |
Prescribing trends in cognition enhancing drugs in Australia. | International psychogeriatrics 20110301 |
Memantine-induced brain activation as a model for the rapid screening of potential novel antipsychotic compounds: exemplified by activity of an mGlu2/3 receptor agonist. | Psychopharmacology 20110301 |
Memantine for non-motor features of Parkinson's disease: a double-blind placebo controlled exploratory pilot trial. | Parkinsonism & related disorders 20110301 |
Effect of memantine on resting state default mode network activity in Alzheimer's disease. | Drugs & aging 20110301 |
Managing cognitive dysfunction through the continuum of Alzheimer's disease: role of pharmacotherapy. | CNS drugs 20110301 |
Amyloid β peptide oligomers directly activate NMDA receptors. | Cell calcium 20110301 |
Effectiveness of adding memantine to an Alzheimer dementia treatment regimen which already includes stable donepezil therapy: a critically appraised topic. | The neurologist 20110301 |
Inhibitory effect of memantine, an NMDA-receptor antagonist, on electroporation-induced inward currents in pituitary GH3 cells. | Biochemical and biophysical research communications 20110218 |
Memantine reduces consumption of highly palatable food in a rat model of binge eating. | Amino acids 20110201 |
Efficacy of memantine in PDD and DLB: an extension study including washout and open-label treatment. | International journal of geriatric psychiatry 20110201 |
Activation of brain histaminergic neurotransmission: a mechanism for cognitive effects of memantine in Alzheimer's disease. | The Journal of pharmacology and experimental therapeutics 20110201 |
Administration of memantine during ethanol withdrawal in neonatal rats: effects on long-term ethanol-induced motor incoordination and cerebellar Purkinje cell loss. | Alcoholism, clinical and experimental research 20110201 |
Memantine prevents hypoglycemia-induced decrements of the cerebral energy status in healthy subjects. | The Journal of clinical endocrinology and metabolism 20110201 |
The effect of co-administration of the NMDA blocker with agonist and antagonist of CB1-receptor on penicillin-induced epileptiform activity in rats. | Epilepsy research 20110201 |
[Pharmacological treatment of nystagmus]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20110201 |
High-performance liquid chromatographic determination of memantine hydrochloride in rat plasma using sensitive fluorometric derivatization. | Journal of separation science 20110201 |
Glutamate receptors in laryngeal cancer cells. | Anticancer research 20110201 |
[Clinical rehabilitative effect of memantine on cognitive and motor disorders in patients with Parkinson's disease]. | Zhonghua yi xue za zhi 20110201 |
[Memantine: the value of combined therapy]. | Revista de neurologia 20110116 |
Membrane cholesterol modulates {beta}-amyloid-dependent tau cleavage by inducing changes in the membrane content and localization of N-methyl-D-aspartic acid receptors. | The Journal of biological chemistry 20110114 |
Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells. | Cell death and differentiation 20110101 |
Targeting glutamate mediated excitotoxicity in Huntington's disease: neural progenitors and partial glutamate antagonist--memantine. | Medical hypotheses 20110101 |
Quantification of the Mg2+-induced potency shift of amantadine and memantine voltage-dependent block in human recombinant GluN1/GluN2A NMDARs. | Neuropharmacology 20110101 |
Memantine in behavioral variant frontotemporal dementia: negative results. | Journal of Alzheimer's disease : JAD 20110101 |
Treatment with cholinesterase inhibitors and memantine of patients in the Alzheimer's Disease Neuroimaging Initiative. | Archives of neurology 20110101 |
Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats. | Molecular pain 20110101 |
CDR state transition probabilities in Alzheimer's disease with and without cholinesterase inhibitor intervention in an observational cohort. | Journal of Alzheimer's disease : JAD 20110101 |
A double-blind, double-dummy, randomized controlled study of memantine versus buprenorphine in naloxone-precipitated acute withdrawal in heroin addicts. | Journal of opioid management 20110101 |
Sustained effects of once-daily memantine treatment on cognition and functional communication skills in patients with moderate to severe Alzheimer's disease: results of a 16-week open-label trial. | Journal of Alzheimer's disease : JAD 20110101 |
Measuring therapeutic efficacy in patients with Alzheimer's disease: role of instruments. | Dementia and geriatric cognitive disorders 20110101 |
An immunohistochemical analysis of the neuroprotective effects of memantine, hyperbaric oxygen therapy, and brimonidine after acute ischemia reperfusion injury. | Molecular vision 20110101 |
The effects of a single memantine treatment on behavioral alterations associated with binge alcohol exposure in neonatal rats. | Neurotoxicology and teratology 20110101 |
Huntington's disease: effect of memantine on FDG-PET brain metabolism? | The Journal of neuropsychiatry and clinical neurosciences 20110101 |
Alzheimer's disease: a review of recent developments. | Annals of African medicine 20110101 |
Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats. | Neuropharmacology 20110101 |
Neuroprotective effect of memantine on hippocampal neurons in infantile rat hydrocephalus. | Turkish neurosurgery 20110101 |
Development of spontaneous neuropathy in NF-κBp50-deficient mice by calcineurin-signal involving impaired NF-κB activation. | Molecular vision 20110101 |
Memantine affects cognitive flexibility in the Morris water maze. | Journal of Alzheimer's disease : JAD 20110101 |
A memantin HCL intoxication responsive to plasmapheresis therapy. | Bratislavske lekarske listy 20110101 |
MR spectroscopy for assessment of memantine treatment in mild to moderate Alzheimer dementia. | Journal of Alzheimer's disease : JAD 20110101 |
Alzheimer's disease--input of vitamin D with mEmantine assay (AD-IDEA trial): study protocol for a randomized controlled trial. | Trials 20110101 |
Acute pharmacokinetics of memantine in the mouse. | Pharmacology 20110101 |
Determination of memantine in plasma and vitreous humour by HPLC with precolumn derivatization and fluorescence detection. | Journal of chromatographic science 20110101 |
Quality of life and the effect of memantine in dementia with lewy bodies and Parkinson's disease dementia. | Dementia and geriatric cognitive disorders 20110101 |
The use of acetyl cholinesterase inhibitors and memantine in nursing home residents. | Acta clinica Belgica 20110101 |
Effects of combined treatment with cognitive enhancer memantine and antidepressant fluoxetine on CYP2D2 metabolic activity in rats. | Neuro endocrinology letters 20110101 |
Activation of N-methyl D-aspartate (NMDA) receptors has no influence on rheological properties of erythrocytes. | Clinical hemorheology and microcirculation 20110101 |
Memantine in everyday clinical practice: a comparison of studies in Germany and Greece. | Dementia and geriatric cognitive disorders 20110101 |
[Mental disorders following delirium tremens]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
Chronic catatonia with obsessive compulsive disorder symptoms treated with lorazepam, memantine, aripiprazole, fluvoxamine and neurosurgery. | BMJ case reports 20110101 |
Memantine shows promise in reducing gambling severity and cognitive inflexibility in pathological gambling: a pilot study. | Psychopharmacology 20101201 |
A pilot trial of memantine and riluzole in ALS: correlation to CSF biomarkers. | Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20101201 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
[Effects of electroacupuncture on expression of Abeta positive cells of the hippocampus and SOD activity in rats with streptozocin-Alzheimer's disease]. | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20101201 |
Synthesis and SAR studies of chiral non-racemic dexoxadrol analogues as uncompetitive NMDA receptor antagonists. | Bioorganic & medicinal chemistry 20101115 |
[Treatment of dementia]. | MMW Fortschritte der Medizin 20101104 |
Memantine is a useful drug to prevent the spatial and non-spatial memory deficits induced by methamphetamine in rats. | Pharmacological research 20101101 |
Treatment options of cognitive impairment in multiple sclerosis. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20101101 |
[Memantine in the pharmacologic treatment of moderately severe to severe Alzheimer's disease in Spain (MEMORY study)]. | Revista de neurologia 20101101 |
Memantine discontinuation and the health status of nursing home residents with Alzheimer's disease. | Journal of the American Medical Directors Association 20101101 |
NMDA receptor antagonists for the treatment of neuropathic pain. | Pain medicine (Malden, Mass.) 20101101 |
Memantine benefits functional abilities in moderate to severe Alzheimer's disease. | The journal of nutrition, health & aging 20101101 |
A randomized, placebo-controlled trial of memantine for functional disability in amyotrophic lateral sclerosis. | Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20101001 |
NMDA-receptor antagonist and morphine decrease CRPS-pain and cerebral pain representation. | Pain 20101001 |
Efficacy of akatinol memantine in moderate cognitive impairments. | Neuroscience and behavioral physiology 20101001 |
Effects of memantine on convulsive reactions and the organization of sleep in krushinskii-molodkina rats with an inherited predisposition to audiogenic convulsions. | Neuroscience and behavioral physiology 20101001 |
Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial. | The Lancet. Neurology 20101001 |
[Vascular dementia]. | Der Nervenarzt 20101001 |
In vivo evidence for functional NMDA receptor blockade by memantine in rat hippocampal neurons. | Journal of neural transmission (Vienna, Austria : 1996) 20101001 |
Improving fragile X-associated tremor/ataxia syndrome symptoms with memantine and venlafaxine. | Journal of clinical psychopharmacology 20101001 |
Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli. | Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 20101001 |
Differential pharmacological responses of catatonia-like signs in frontotemporal dementia. | Neurocase 20101001 |
The effect of memantine on sleep behaviour in dementia with Lewy bodies and Parkinson's disease dementia. | International journal of geriatric psychiatry 20101001 |
HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20100901 |
Memantine depresses glutamate release through inhibition of voltage-dependent Ca2+ entry and protein kinase C in rat cerebral cortex nerve terminals: an NMDA receptor-independent mechanism. | Neurochemistry international 20100901 |
A placebo-controlled trial of memantine for cocaine dependence with high-value voucher incentives during a pre-randomization lead-in period. | Drug and alcohol dependence 20100901 |
Antinociceptive Effect of Memantine and Morphine on Vincristine-induced Peripheral Neuropathy in Rats. | The Korean journal of pain 20100901 |
Once-daily memantine: pharmacokinetic and clinical considerations. | Journal of the American Geriatrics Society 20100901 |
Current treatments for patients with Alzheimer disease. | The Journal of the American Osteopathic Association 20100901 |
Modern care for patients with Alzheimer disease: rationale for early intervention. | The Journal of the American Osteopathic Association 20100901 |
Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100818 |
Pharmacologic dissociation between impulsivity and alcohol drinking in high alcohol preferring mice. | Alcoholism, clinical and experimental research 20100801 |
Predictors of adherence among Alzheimer's disease patients receiving oral therapy. | Current medical research and opinion 20100801 |
HIV-1 gp120-induced injury to the blood-brain barrier: role of metalloproteinases 2 and 9 and relationship to oxidative stress. | Journal of neuropathology and experimental neurology 20100801 |
Drugmakers dance with autism. | Nature biotechnology 20100801 |
Profile: Nicholas Dodman. Can dogs behaving badly suggest a new way to treat OCD? | Science (New York, N.Y.) 20100723 |
Memantine exacerbates myoclonic jerks in a rat model of posthypoxic myoclonus. | Brain research 20100709 |
Breast cancer expresses functional NMDA receptors. | Breast cancer research and treatment 20100701 |
Dynamin 1 depletion and memory deficits in rats treated with Abeta and cerebral ischemia. | Journal of neuroscience research 20100701 |
Effect of memantine treatment on regional cortical metabolism in Alzheimer's disease. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20100701 |
Memantine ER, a once-daily formulation for the treatment of Alzheimer's disease. | Expert opinion on pharmacotherapy 20100701 |
Memantine-related psychotic symptoms in a patient with bipolar disorder. | The Journal of clinical psychiatry 20100701 |
[Drug therapy for Alzheimer's disease]. | Brain and nerve = Shinkei kenkyu no shinpo 20100701 |
Clinical practice. Early Alzheimer's disease. | The New England journal of medicine 20100610 |
Dose-related effects of memantine on a mismatch negativity-like response in anesthetized rats. | Neuroscience 20100602 |
A review comparing the safety and tolerability of memantine with the acetylcholinesterase inhibitors. | International journal of geriatric psychiatry 20100601 |
Acetylcholinesterase inhibitors and memantine for neuroenhancement in healthy individuals: a systematic review. | Pharmacological research 20100601 |
Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism. | The Journal of pharmacology and experimental therapeutics 20100601 |
Changes in cerebral glucose metabolism in patients with posttraumatic cognitive impairment after memantine therapy: a preliminary study. | Annals of nuclear medicine 20100601 |
Simultaneous determination of memantine and amantadine in human plasma as fluorescein derivatives by micellar electrokinetic chromatography with laser-induced fluorescence detection and its clinical application. | Electrophoresis 20100601 |
Synthesis and NMDA receptor affinity of fluorinated dioxadrol analogues. | Bioorganic & medicinal chemistry 20100601 |
Memantine for cognitive impairment in multiple sclerosis: a randomized placebo-controlled trial. | Multiple sclerosis (Houndmills, Basingstoke, England) 20100601 |
How do we treat people with dementia in Croatia. | Psychiatria Danubina 20100601 |
Effects of the uncompetitive nmda receptor antagonist memantine on recognition memory in rats. | Georgian medical news 20100601 |
Protective effects of memantine and epicatechin on catechol-induced toxicity on Müller cells in vitro. | Toxicology 20100527 |
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents. | Journal of medicinal chemistry 20100513 |
Pigment epithelium-derived factor up-regulation induced by memantine, an N-methyl-D-aspartate receptor antagonist, is involved in increased proliferation of hippocampal progenitor cells. | Neuroscience 20100505 |
Inhibition of apoptosis in human retinal pigment epithelial cells treated with benzo(e)pyrene, a toxic component of cigarette smoke. | Investigative ophthalmology & visual science 20100501 |
Memantine ameliorates scopolamine-induced amnesia in chicks trained on taste-avoidance learning. | Neurobiology of learning and memory 20100501 |
Effects of the non-competitive NMDA receptor antagonist memantine on the volitional consumption of ethanol by alcohol-preferring rats. | Basic & clinical pharmacology & toxicology 20100501 |
Combination treatments in Alzheimer's disease: risks and benefits. | Expert review of neurotherapeutics 20100501 |
Crossover trial of gabapentin and memantine as treatment for acquired nystagmus. | Annals of neurology 20100501 |
Effect of memantine on overactive detrusor in rats with spinal cord injury. | The Kaohsiung journal of medical sciences 20100501 |
[Cost of illness in Alzheimer's disease]. | Medizinische Klinik (Munich, Germany : 1983) 20100501 |
Antimanic and mood-stabilizing effect of memantine as an augmenting agent in treatment-resistant bipolar disorder. | Bipolar disorders 20100501 |
[Variability and trends in dementia drug consumption in Castile-La Mancha (Spain). Estimated prevalence of Alzheimer's disease]. | Neurologia (Barcelona, Spain) 20100501 |
Neurochemical and behavioural effects of acute and chronic memantine administration in rats: Further support for NMDA as a new pharmacological target for the treatment of depression? | Brain research bulletin 20100405 |
A 1H-MR spectroscopy study of changes in glutamate and glutamine (Glx) concentrations in frontal spectra after administration of memantine. | Cerebral cortex (New York, N.Y. : 1991) 20100401 |
Safety and tolerability of rivastigmine capsule with memantine in patients with probable Alzheimer's disease: a 26-week, open-label, prospective trial (Study ENA713B US32). | International journal of geriatric psychiatry 20100401 |
Regulation of Kv2.1 phosphorylation in an animal model of anoxia. | Neurobiology of disease 20100401 |
Memantine improves memory for taste-avoidance learning in day-old chicks exposed to isolation stress. | Pharmacology, biochemistry, and behavior 20100401 |
[New perspectives on molecular and genic therapies in Down syndrome]. | Medecine sciences : M/S 20100401 |
NMDA antagonist memantine improves levodopa-induced dyskinesias and 'on-off' phenomena in Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20100315 |
Acquired pendular nystagmus in multiple sclerosis: an examiner-blind cross-over treatment study of memantine and gabapentin. | Journal of neurology 20100301 |
Memantine versus donepezil in mild to moderate Alzheimer's disease: a randomized trial with magnetic resonance spectroscopy. | European journal of neurology 20100301 |
Prescribing of drugs for Alzheimer's disease: a South African database analysis. | International psychogeriatrics 20100301 |
Off-label medication use in frontotemporal dementia. | American journal of Alzheimer's disease and other dementias 20100301 |
[Lying with statistic--today: the meta-analysis]. | Deutsche medizinische Wochenschrift (1946) 20100301 |
[On the role of MAO B inhibitors and NMDA antagonists in the therapy of Parkinson's disease]. | Fortschritte der Neurologie-Psychiatrie 20100301 |
Solid state stabilisation of the orally delivered drugs atenolol, glibenclamide, memantine and paracetamol through their complexation with cucurbit[7]uril. | Organic & biomolecular chemistry 20100221 |
Memantine treatment decreases levels of secreted Alzheimer's amyloid precursor protein (APP) and amyloid beta (A beta) peptide in the human neuroblastoma cells. | Neuroscience letters 20100205 |
A 25-week, open-label trial investigating rivastigmine transdermal patches with concomitant memantine in mild-to-moderate Alzheimer's disease: a post hoc analysis. | Current medical research and opinion 20100201 |
Deramciclane improves object recognition in rats: potential role of NMDA receptors. | Pharmacology, biochemistry, and behavior 20100201 |
Memantine: 'hypothesis testing' not 'disease modifying' in Alzheimer's disease. | The American journal of pathology 20100201 |
A randomized trial of memantine as treatment for spasticity in multiple sclerosis. | Multiple sclerosis (Houndmills, Basingstoke, England) 20100201 |
Use of memantine (akatinol) for the correction of cognitive impairments in Parkinson's disease complicated by dementia. | Neuroscience and behavioral physiology 20100201 |
Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice. | The American journal of pathology 20100201 |
Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: possible pharmacological strategies. | Cell calcium 20100201 |
A single-blinded case-control study of memantine in severe obsessive-compulsive disorder. | Journal of clinical psychopharmacology 20100201 |
The dysregulation of intracellular calcium in Alzheimer disease. | Cell calcium 20100201 |
Model of methadone-induced hyperalgesia in rats and effect of memantine. | European journal of pharmacology 20100125 |
Studies on wakefulness-promoting effect of memantine in rats. | Behavioural brain research 20100120 |
Okadaic acid (ICV) induced memory impairment in rats: a suitable experimental model to test anti-dementia activity. | Brain research 20100114 |
Memantine lowers amyloid-beta peptide levels in neuronal cultures and in APP/PS1 transgenic mice. | Journal of neuroscience research 20100101 |
Eight-year prescription trends of memantine and cholinesterase inhibitors among persons 65 years and older in Germany. | International clinical psychopharmacology 20100101 |
New oxapolycyclic cage amines with NMDA receptor antagonist and trypanocidal activities. | Bioorganic & medicinal chemistry 20100101 |
Pharmacological treatment of Alzheimer's disease: effect of race and demographic variables. | Journal of Alzheimer's disease : JAD 20100101 |
Lack of association between serum brain-derived neurotrophic factor levels and improvement of schizophrenia symptoms in a double-blind, randomized, placebo-controlled trial of memantine as adjunctive therapy to clozapine. | The Journal of clinical psychiatry 20100101 |
Folic Acid potentiates the effect of memantine on spatial learning and neuronal protection in an Alzheimer's disease transgenic model. | Journal of Alzheimer's disease : JAD 20100101 |
Neuroprotective effects of bis(7)-tacrine against glutamate-induced retinal ganglion cells damage. | BMC neuroscience 20100101 |
Lower Barthel Index scores predict less prescription of pharmacological therapy in elderly patients with Alzheimer disease. | Dementia and geriatric cognitive disorders 20100101 |
Drugs for Alzheimer's disease. | Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20100101 |
Memantine for AIDS dementia complex: open-label report of ACTG 301. | HIV clinical trials 20100101 |
Intracisternal administration of NR2 antagonists attenuates facial formalin-induced nociceptive behavior in rats. | Journal of orofacial pain 20100101 |
Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome. | Journal of Alzheimer's disease : JAD 20100101 |
Cost effectiveness of memantine in Alzheimer's disease in the UK. | Journal of medical economics 20100101 |
[Consensus statement 'Dementia 2010' of the Austrian Alzheimer Society]. | Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20100101 |
[Memantine for treatment of behavioural disturbances and psychotic symptoms in moderate to moderately severe Alzheimer dementia: a naturalistic study in outpatient services in Austria]. | Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20100101 |
Comparison of adverse drug reactions with donepezil versus memantine: analysis of the French Pharmacovigilance Database. | Therapie 20100101 |
Pilot trial of memantine in primary progressive aphasia. | Alzheimer disease and associated disorders 20100101 |
A pilot efficacy and tolerability trial of memantine for essential tremor. | Clinical neuropharmacology 20100101 |
Late onset Alzheimer's disease in older people. | Clinical interventions in aging 20100101 |
[Treatment of Alzheimer's disease and future approaches]. | Therapie 20100101 |
Characterisation of the expression of NMDA receptors in human astrocytes. | PloS one 20100101 |
Sensitive and rapid HPLC method for determination of memantine in human plasma using OPA derivatization and fluorescence detection: application to pharmacokinetic studies. | Scientia pharmaceutica 20100101 |
[Akatinol memantine in patients with vascular cognitive disorders]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
[Clinical features of the formation and possibilities of treatment of posttraumatic cognitive disturbances]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
Differences between physician and caregiver evaluations in Alzheimer's disease. | Functional neurology 20100101 |
[The use of akatinol memantine in the residual phase of stroke]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
Dementia. | BMJ clinical evidence 20100101 |
Autism. | BMJ clinical evidence 20100101 |
Effects of memantine on soluble Alphabeta(25-35)-induced changes in peptidergic and glial cells in Alzheimer's disease model rat brain regions. | Neuroscience 20091215 |
Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons. | Cellular and molecular neurobiology 20091201 |
Open-label memantine in fragile X syndrome. | Journal of autism and developmental disorders 20091201 |
International price comparisons of Alzheimer's drugs: a way to close the affordability gap. | International psychogeriatrics 20091201 |
Memantine for the prophylaxis of chronic tension-type headache. | Current pain and headache reports 20091201 |
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. | Nature medicine 20091201 |
Memantine strikes the perfect balance. | Nature medicine 20091201 |
[Alzheimer dementia. Memantine: value for patient and caregivers]. | MMW Fortschritte der Medizin 20091105 |
The effects of the glutamate antagonist memantine on brain activation to an auditory perception task. | Human brain mapping 20091101 |
Effect of memantine on the levels of neuropeptides and microglial cells in the brain regions of rats with neuropathic pain. | Journal of molecular neuroscience : MN 20091101 |
Management of agitation and aggression associated with Alzheimer's disease: controversies and possible solutions. | Current opinion in psychiatry 20091101 |
The effect of memantine and levodopa/carbidopa on the responses of phrenic nerve-diaphragm preparations from aged rats. | Medical science monitor : international medical journal of experimental and clinical research 20091101 |
Effects of anti-dementia drugs on morphine-induced somnolence. | Biological & pharmaceutical bulletin 20091101 |
Alzheimer's disease: Seeing the signs early. | Journal of the American Academy of Nurse Practitioners 20091101 |
Minimally-responsive head injury survivors may have chronic catatonia reversed years after an accident. | Singapore medical journal 20091101 |
Cost-effectiveness: cholinesterase inhibitors and memantine in vascular dementia. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20091101 |
The effects of NMDA receptor antagonists over intestinal ischemia/reperfusion injury in rats. | European journal of pharmacology 20091025 |
Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist. | Toxicology and applied pharmacology 20091015 |
Emerging role of glutamate in the pathophysiology of major depressive disorder. | Brain research reviews 20091001 |
Role of N-methyl-D-aspartate receptor antagonists in postoperative pain management. | Current opinion in anaesthesiology 20091001 |
Memantine binding to a superficial site on NMDA receptors contributes to partial trapping. | The Journal of physiology 20091001 |
Memantine: a review of its use in moderate to severe Alzheimer's disease. | CNS drugs 20091001 |
Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. | The Journal of clinical psychiatry 20091001 |
[Final report is now available. IQWiG doubts the effectiveness of memantine]. | MMW Fortschritte der Medizin 20090924 |
Memantine blocks sensitization to the rewarding effects of morphine. | Brain research 20090908 |
Memantine prevents sensitivity to excitotoxic cell death of rat cortical neurons expressing human truncated tau protein. | Cellular and molecular neurobiology 20090901 |
Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine. | Brain : a journal of neurology 20090901 |
Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090901 |
Cholinesterase inhibitor and N-methyl-D-aspartic acid receptor antagonist use in older adults with end-stage dementia: a survey of hospice medical directors. | Journal of palliative medicine 20090901 |
Treatment effects of Memantine on language in moderate to severe Alzheimer's disease patients. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20090901 |
Current Alzheimer's disease clinical trials: methods and placebo outcomes. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20090901 |
Memantine prevents cardiomyocytes nuclear size reduction in the left ventricle of rats exposed to cold stress. | Clinics (Sao Paulo, Brazil) 20090901 |
Dual action of memantine in Alzheimer disease: a hypothesis. | Taiwanese journal of obstetrics & gynecology 20090901 |
Memanti-nium chloride 0.1-hydrate. | Acta crystallographica. Section E, Structure reports online 20090901 |
The Alzheimer's disease drug memantine increases the number of radial glia-like progenitor cells in adult hippocampus. | Glia 20090801 |
Combined use of pregabalin and memantine in fibromyalgia syndrome treatment: a novel analgesic and neuroprotective strategy? | Medical hypotheses 20090801 |
Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain. | Neuropharmacology 20090801 |
Neuroprotection: extrapolating from neurologic diseases to the eye. | American journal of ophthalmology 20090801 |
The pharmacological treatment of nystagmus: a review. | Expert opinion on pharmacotherapy 20090801 |
Memantine: heart failure: harmful drug. | Prescrire international 20090801 |
[Effects of memantine on convulsive reactions and sleep-waking cycle in Krushinskiĭ-Molodkina strain rats with the inherited predisposition to audiogenic convulsions]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090801 |
Neuroprotective effect of memantine combined with topiramate in hypoxic-ischemic brain injury. | Brain research 20090728 |
Efficacy and safety of memantine in Lewy body dementia. | Neuroscience and behavioral physiology 20090701 |
Memantine: a new hope for treatment of Lewy body-related dementias? | The Lancet. Neurology 20090701 |
Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial. | The Lancet. Neurology 20090701 |
An involvement of BDNF and PI3-K/Akt in the anti-apoptotic effect of memantine on staurosporine-evoked cell death in primary cortical neurons. | Apoptosis : an international journal on programmed cell death 20090701 |
Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons. | Neurotoxicity research 20090701 |
Randomized controlled trial of memantine in dementia associated with Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20090615 |
Experimental glutamatergic excitotoxicity in rabbit retinal ganglion cells: block by memantine. | Investigative ophthalmology & visual science 20090601 |
Recent clinical findings with memantine should not mean that the idea of neuroprotection in glaucoma is abandoned. | Acta ophthalmologica 20090601 |
Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease. | Journal of neurology, neurosurgery, and psychiatry 20090601 |
The effects of memantine on prepulse inhibition. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601 |
Two cases of discontinuation syndrome following cessation of memantine. | Geriatrics & gerontology international 20090601 |
[Antidementia drugs]. | Therapeutische Umschau. Revue therapeutique 20090601 |
The combined effects of memantine and fluoxetine on an animal model of obsessive compulsive disorder. | Experimental and clinical psychopharmacology 20090601 |
Effects of memantine on latent inhibition of active avoidance in wistar rats. | Bulletin of experimental biology and medicine 20090601 |
Age at onset of first depressive episode as a predictor for escitalopram treatment of major depression comorbid with alcohol dependence. | Psychiatry research 20090515 |
Treatment of Alzheimer's disease in the long-term-care setting. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090515 |
Memantine induces reversible neurologic impairment in patients with MS. | Neurology 20090512 |
Understanding pseudo: the symptoms are real, the cause is unclear. | Neurology 20090512 |
Effects of topiramate and other anti-glutamatergic drugs on the acute intoxicating actions of ethanol in mice: modulation by genetic strain and stress. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090501 |
Effects of memantine on cognition in patients with moderate to severe Alzheimer's disease: post-hoc analyses of ADAS-cog and SIB total and single-item scores from six randomized, double-blind, placebo-controlled studies. | International journal of geriatric psychiatry 20090501 |
Influence of memantine on brain monoaminergic neurotransmission parameters in mice: neurochemical and behavioral study. | Biological & pharmaceutical bulletin 20090501 |
Evidence for glutamatergic neurotransmission in cognitive control in an auditory attention task. | Neuroscience letters 20090501 |
Pre-ischemic treatment with memantine reversed the neurochemical and behavioural parameters but not energy metabolites in middle cerebral artery occluded rats. | Pharmacology, biochemistry, and behavior 20090501 |
Memantine and constraint-induced aphasia therapy in chronic poststroke aphasia. | Annals of neurology 20090501 |
Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines. | Bioorganic & medicinal chemistry 20090415 |
Memantine treatment reduces the expression of the K(+)/Cl(-) cotransporter KCC2 in the hippocampus and cerebral cortex, and attenuates behavioural responses mediated by GABA(A) receptor activation in mice. | Brain research 20090410 |
A randomized, placebo-controlled study of memantine as adjunctive treatment in patients with schizophrenia. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090401 |
NMDA receptor antagonist memantine promotes cell proliferation and production of mature granule neurons in the adult hippocampus. | Neuroscience research 20090401 |
Potency, voltage-dependency, agonist concentration-dependency, blocking kinetics and partial untrapping of the uncompetitive N-methyl-D-aspartate (NMDA) channel blocker memantine at human NMDA (GluN1/GluN2A) receptors. | Neuropharmacology 20090401 |
Treatment practices of mild cognitive impairment in California Alzheimer's Disease Centers. | Journal of the American Geriatrics Society 20090401 |
Update on neuropsychiatric symptoms of dementia: evaluation and management. | Geriatrics 20090401 |
Drugs to treat Alzheimer's disease. | Journal of psychosocial nursing and mental health services 20090401 |
When should drug treatment be started for people with dementia? | Maturitas 20090320 |
Mg2+ imparts NMDA receptor subtype selectivity to the Alzheimer's drug memantine. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090304 |
[Treatment of degenerative dementia disorders--who should be treated?]. | Ugeskrift for laeger 20090302 |
N-methyl-D-aspartate receptor antagonists have variable affect in 3-nitropropionic acid toxicity. | Neurochemical research 20090301 |
Cognitive effects of memantine in postmenopausal women at risk of dementia: a pilot study. | Acta neurologica Scandinavica 20090301 |
Memantine for prophylaxis of chronic tension-type headache--a double-blind, randomized, crossover clinical trial. | Cephalalgia : an international journal of headache 20090301 |
Memantine and acetylcholinesterase inhibitor treatment in cases of CDR 0.5 or questionable impairment. | Journal of Alzheimer's disease : JAD 20090301 |
Memantine in the preventive treatment for migraine and refractory migraine. | Headache 20090301 |
Memantine (Namenda, Forest Pharmaceuticals). | Issues in mental health nursing 20090301 |
Characteristic effects of anti-dementia drugs on rat sleep patterns. | Journal of pharmacological sciences 20090301 |
[Therapy of Alzheimer disease]. | Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20090301 |
Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils. | Brain research 20090213 |
Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of pramipexole in human plasma: application to a clinical pharmacokinetic study. | Biomedical chromatography : BMC 20090201 |
Glutamate-induced NFkappaB activation in the retina. | Investigative ophthalmology & visual science 20090201 |
Memantine blocks mitochondrial OPA1 and cytochrome c release and subsequent apoptotic cell death in glaucomatous retina. | Investigative ophthalmology & visual science 20090201 |
Memantine augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial. | Journal of clinical psychopharmacology 20090201 |
Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytes. | British journal of pharmacology 20090201 |
Three steps forward, two steps back in helping people with dementia. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20090201 |
Memantine dosing in patients with dementia. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20090201 |
Psychosis in the elderly. | The American journal of psychiatry 20090201 |
Memantine as an augmenting agent for severe pediatric OCD. | The American journal of psychiatry 20090201 |
Racial/ethnic disparities in medication use among veterans with hypertension and dementia: a national cohort study. | The Annals of pharmacotherapy 20090201 |
New developments in the treatment of Alzheimer's disease. | The Journal of clinical psychiatry 20090201 |
Memantine for dementia in people with Down syndrome. | The Cochrane database of systematic reviews 20090121 |
Augmentation of nitrite therapy in cerebral ischemia by NMDA receptor inhibition. | Biochemical and biophysical research communications 20090116 |
Role of N-methyl-D-aspartate receptors in polychlorinated biphenyl mediated neurotoxicity. | Toxicology letters 20090110 |
Differential involvement of glutamatergic mechanisms in the cognitive and subjective effects of smoking. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090101 |
Different effects of two N-methyl-D-aspartate receptor antagonists on seizures, spontaneous behavior, and motor performance in immature rats. | Epilepsy & behavior : E&B 20090101 |
Nightmares and memantine: a case report and review of literature. | Journal of the American Medical Directors Association 20090101 |
Memantine therapy of behavioral symptoms in community-dwelling patients with moderate to severe Alzheimer's disease. | Dementia and geriatric cognitive disorders 20090101 |
Memantine (Namenda) for neuropathic pain. | The American journal of hospice & palliative care 20090101 |
Differential efficacy of memantine for obsessive-compulsive disorder vs. generalized anxiety disorder: an open-label trial. | Psychopharmacology bulletin 20090101 |
Memantine: a comprehensive review of safety and efficacy. | Expert opinion on drug safety 20090101 |
Donepezil in severe Alzheimer's disease. | American journal of Alzheimer's disease and other dementias 20090101 |
Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network. | Dementia and geriatric cognitive disorders 20090101 |
Protective effect of memantine against Doxorubicin toxicity in primary neuronal cell cultures: influence a development stage. | Neurotoxicity research 20090101 |
Memantine in moderately-severe-to-severe Alzheimer's disease: a postmarketing surveillance study. | Drugs & aging 20090101 |
Treatment of acquired periodic alternating nystagmus with memantine: a case report. | Clinical neuropharmacology 20090101 |
Memantine efficacy and safety in patients with acute mania associated with bipolar I disorder: a pilot evaluation. | Clinical neuropharmacology 20090101 |
DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT. | Trials 20090101 |
Increased expression of PAD2 after repeated intracerebroventricular infusions of soluble Abeta(25-35) in the Alzheimer's disease model rat brain: effect of memantine. | Cellular & molecular biology letters 20090101 |
Memantine inhibits calpain-mediated truncation of GSK-3 induced by NMDA: implications in Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20090101 |
Effects of memantine on cerebrospinal fluid biomarkers of neurofibrillary pathology. | Journal of Alzheimer's disease : JAD 20090101 |
[Efficacy of acatinol memantine in mild cognitive disorder]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101 |
Current treatments of Alzheimer disease: are main caregivers satisfied with the drug treatments received by their patients? | Dementia and geriatric cognitive disorders 20090101 |
An open-label study of memantine treatment in 3 subtypes of frontotemporal lobar degeneration. | Alzheimer disease and associated disorders 20090101 |
Memantine: a review of studies into its safety and efficacy in treating Alzheimer's disease and other dementias. | Clinical interventions in aging 20090101 |
Variability in the prescription of cholinesterase inhibitors and memantine. | Dementia and geriatric cognitive disorders 20090101 |
Anti-apoptotic effect of memantine against staurosporine- and low-potassium-induced cell death in cerebellar granule cells: a development-dependent effect. | Pharmacological reports : PR 20090101 |
Treatments for fragile X syndrome: a closer look at the data. | Developmental disabilities research reviews 20090101 |
Altered glutamate neurotransmission and behaviour in dementia: evidence from studies of memantine. | Current molecular pharmacology 20090101 |
Three-year follow-up of a patient with early-onset Alzheimer's disease with presenilin-2 N141I mutation - case report and review of the literature. | European journal of medical research 20081203 |
Effects of memantine on neuronal structure and conditioned fear in the Tg2576 mouse model of Alzheimer's disease. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081201 |
Longitudinal multimodal imaging in mild to moderate Alzheimer disease: a pilot study with memantine. | Journal of neurology, neurosurgery, and psychiatry 20081201 |
[Pharmacotherapy of central oculomotor disorders]. | Der Nervenarzt 20081201 |
Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081201 |
Alcohol withdrawal-induced hippocampal neurotoxicity in vitro and seizures in vivo are both reduced by memantine. | Alcoholism, clinical and experimental research 20081201 |
Comparisons of the influenza virus A M2 channel binding affinities, anti-influenza virus potencies and NMDA antagonistic activities of 2-alkyl-2-aminoadamantanes and analogues. | Bioorganic & medicinal chemistry letters 20081201 |
Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs. | Bioorganic & medicinal chemistry 20081201 |
New approaches to the treatment of frontotemporal lobar degeneration. | Current opinion in neurology 20081201 |
Influence of NMDA and non-NMDA antagonists on acute and inflammatory pain in the trigeminal territory: a placebo control study. | Arquivos de neuro-psiquiatria 20081201 |
The influence of various glutamate receptors antagonists on anxiety-like effect of ethanol withdrawal in a plus-maze test in rats. | European journal of pharmacology 20081119 |
Diagnosis and treatment of dementia: 5. Nonpharmacologic and pharmacologic therapy for mild to moderate dementia. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20081104 |
The effect of 12-week open-label memantine treatment on cognitive function improvement in patients with alcohol-related dementia. | The international journal of neuropsychopharmacology 20081101 |
Antagonism of glutamatergic NMDA and mGluR5 receptors decreases consumption of food in baboon model of binge-eating disorder. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20081101 |
Memantine protects rat cortical cultured neurons against beta-amyloid-induced toxicity by attenuating tau phosphorylation. | The European journal of neuroscience 20081101 |
Randomized, placebo-controlled, crossover trial of memantine for cognitive changes with corticosteroid therapy. | Biological psychiatry 20081015 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
Blocking kinetics of memantine on NR1a/2A receptors recorded in inside-out and outside-out patches from Xenopus oocytes. | Journal of neural transmission (Vienna, Austria : 1996) 20081001 |
Therapeutically relevant plasma concentrations of memantine produce significant L-N-methyl-D-aspartate receptor occupation and do not impair learning in rats. | Behavioural pharmacology 20081001 |
Pharmacological treatment in moderate-to-severe Alzheimer's disease. | Expert opinion on pharmacotherapy 20081001 |
Early use of memantine for neuropathic pain. | Anesthesia and analgesia 20081001 |
Profound pain reduction after induction of memantine treatment in two patients with severe phantom limb pain. | Anesthesia and analgesia 20081001 |
Ultra-low dose ketamine and memantine treatment for pain in an opioid-tolerant oncology patient. | Anesthesia and analgesia 20081001 |
Cholinesterase inhibitors and memantine: best practices. | CNS spectrums 20081001 |
Memantine in the preventive treatment of refractory migraine. | Headache 20081001 |
Tolerability of switching from donepezil to memantine treatment in patients with moderate to severe Alzheimer's disease. | International journal of geriatric psychiatry 20080901 |
Memantine in the treatment of binge eating disorder: an open-label, prospective trial. | The International journal of eating disorders 20080901 |
Novel regimen through combination of memantine and tea polyphenol for neuroprotection against brain excitotoxicity. | Journal of neuroscience research 20080901 |
A novel procedure for assessing the effects of drugs on satiation in baboons: effects of memantine and dexfenfluramine. | Psychopharmacology 20080901 |
Does memantine induce bradycardia? A study in the French PharmacoVigilance Database. | Pharmacoepidemiology and drug safety 20080901 |
Acute liver failure-induced death of rats is delayed or prevented by blocking NMDA receptors in brain. | American journal of physiology. Gastrointestinal and liver physiology 20080901 |
Memantine leads to behavioral improvement and amyloid reduction in Alzheimer's-disease-model transgenic mice shown as by micromagnetic resonance imaging. | Journal of neuroscience research 20080901 |
Blocking NMDA receptor signaling does not decrease hormonal counterregulation to hypoglycemia in humans. | Psychoneuroendocrinology 20080901 |
Ca2+ inhibits the association of memantine with N-methyl-D-aspartate (NMDA) receptor-gated ion channels. | Biological & pharmaceutical bulletin 20080901 |
Normal pressure hydrocephalus presenting as Othello syndrome: case presentation and review of the literature. | The American journal of psychiatry 20080901 |
The effect of N-methyl-D-aspartate receptor antagonist (memantine) on esophageal and gastric smooth muscle: functional investigation in a rat hydrocephalus model. | Journal of pediatric surgery 20080901 |
[Alzheimer type dementia]. | Revue de l'infirmiere 20080901 |
Racial and ethnic disparities in the treatment of dementia among Medicare beneficiaries. | The journals of gerontology. Series B, Psychological sciences and social sciences 20080901 |
Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush. | Journal of medicinal chemistry 20080814 |
Memantine upregulates BDNF and prevents dopamine deficits in SIV-infected macaques: a novel pharmacological action of memantine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080801 |
A systematic review of off-label uses of memantine for psychiatric disorders. | Progress in neuro-psychopharmacology & biological psychiatry 20080801 |
Cognitive and behavioural impairment in Parkinson's disease. | International review of psychiatry (Abingdon, England) 20080801 |
Methylmercury increases N-methyl-D-aspartate receptors on human SH-SY 5Y neuroblastoma cells leading to neurotoxicity. | Toxicology 20080730 |
Memantine prevents the cognitive impairment induced by 3,4-methylenedioxymethamphetamine in rats. | European journal of pharmacology 20080728 |
A 6-month, open-label study of memantine in patients with frontotemporal dementia. | International journal of geriatric psychiatry 20080701 |
Assessing transneuronal dysfunction utilizing manganese-enhanced MRI (MEMRI). | Magnetic resonance in medicine 20080701 |
Alzheimer's disease--towards more patient-centred and meaningful clinical outcomes. | Annals of the Academy of Medicine, Singapore 20080701 |
NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080625 |
Neuroprotective effects of memantine in a mouse model of retinal degeneration induced by rotenone. | Brain research 20080618 |
Memantine does not show intracellular block of the NMDA receptor channel. | European journal of pharmacology 20080610 |
Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080601 |
Effects of memantine and MK-801 on ischemia in an experimental model of acute subdural hematoma. | Neurological research 20080601 |
Cognition-enhancing and anxiolytic effects of memantine. | Neuropharmacology 20080601 |
Memantine protects against amphetamine derivatives-induced neurotoxic damage in rodents. | Neuropharmacology 20080601 |
Current and future therapy in Alzheimer's disease. | Fundamental & clinical pharmacology 20080601 |
Galantamine-induced pisa syndrome: memantine as an alternative. | International journal of geriatric psychiatry 20080601 |
Glutamate receptor-mediated restoration of experience-dependent place field expansion plasticity in aged rats. | Behavioral neuroscience 20080601 |
Pooled analyses on cognitive effects of memantine in patients with moderate to severe Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20080601 |
Combined blockade of AMPA and NMDA receptors in the brain of rats prevents pentylenetetrazole-induced clonic and tonic-clonic seizures without ataxia. | Bulletin of experimental biology and medicine 20080601 |
Effects of glutamate-related drugs on marble-burying behavior in mice: implications for obsessive-compulsive disorder. | European journal of pharmacology 20080531 |
Glutamate-mediated neuroplasticity in an animal model of self-injurious behaviour. | Behavioural brain research 20080516 |
Bis(7)-tacrine prevents glutamate-induced excitotoxicity more potently than memantine by selectively inhibiting NMDA receptors. | Biochemical and biophysical research communications 20080516 |
Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study. | Progress in neuro-psychopharmacology & biological psychiatry 20080515 |
The use of the hippocampal slice preparation in the study of Alzheimer's disease. | European journal of pharmacology 20080506 |
Effect of memantine on CBF and CMRO2 in patients with early Parkinson's disease. | Acta neurologica Scandinavica 20080501 |
Improvement in behavioural symptoms in patients with moderate to severe Alzheimer's disease by memantine: a pooled data analysis. | International journal of geriatric psychiatry 20080501 |
Toxicology profile of N-methyl-D-aspartate antagonists delivered by intrathecal infusion in the canine model. | Anesthesiology 20080501 |
Dementia medications in palliative care #174. | Journal of palliative medicine 20080501 |
Memantine enhances the inhibitory effects of naltrexone on ethanol consumption. | European journal of pharmacology 20080428 |
Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080423 |
Memantine increases brain production of kynurenic acid via protein kinase A-dependent mechanism. | Neuroscience letters 20080418 |
Memantine-induced hepatitis with cholestasis in a very elderly patient. | Annals of internal medicine 20080415 |
AAFP and ACP release guideline on dementia treatment. | American family physician 20080415 |
Non-associative learning in larval zebrafish. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080401 |
Tinnitus treatment with memantine. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20080401 |
Pharmacokinetics of single-dose and multiple-dose memantine in healthy chinese volunteers using an analytic method of liquid chromatography-tandem mass spectrometry. | Clinical therapeutics 20080401 |
Suppression of saccadic intrusions in hereditary ataxia by memantine. | Neurology 20080304 |
Summaries for patients. Drug treatment for patients with dementia: American College of Physicians and American Academy of Family Physicians recommendations. | Annals of internal medicine 20080304 |
Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. | Annals of internal medicine 20080304 |
Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline. | Annals of internal medicine 20080304 |
Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia. | Psychopharmacology 20080301 |
Improvement of contextual memory by S 24795 in aged mice: comparison with memantine. | Psychopharmacology 20080301 |
Memantine for agitation/aggression and psychosis in moderately severe to severe Alzheimer's disease: a pooled analysis of 3 studies. | The Journal of clinical psychiatry 20080301 |
Memantine-induced myoclonus and delirium exacerbated by trimethoprim. | The Annals of pharmacotherapy 20080301 |
The spectrum of recurrent thoughts and behaviors in frontotemporal dementia. | CNS spectrums 20080301 |
Course, prognosis, and management of psychosis in Parkinson's disease: are current treatments really effective? | CNS spectrums 20080301 |
Double-blind, randomized comparison of memantine and escitalopram for the treatment of major depressive disorder comorbid with alcohol dependence. | The Journal of clinical psychiatry 20080301 |
Psychosis and agitation in dementia: should general psychiatrists care? | The Journal of clinical psychiatry 20080301 |
Effects of memantine on mitochondrial function. | Biochemical pharmacology 20080215 |
Donepezil markedly potentiates memantine neurotoxicity in the adult rat brain. | Neurobiology of aging 20080201 |
Transient allodynia pain models in mice for early assessment of analgesic activity. | British journal of pharmacology 20080201 |
Addition of memantine to antipsychotic treatment in schizophrenia inpatients with residual symptoms: A preliminary study. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080201 |
Resolution of superior oblique myokymia with memantine. | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20080201 |
NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats. | Psychopharmacology 20080201 |
Memantine agonist action at dopamine D2High receptors. | Synapse (New York, N.Y.) 20080201 |
Memantine and NMDA antagonism for chronic migraine: a potentially novel therapeutic approach? | Headache 20080201 |
Ketamine followed by memantine for the treatment of major depression. | The Australian and New Zealand journal of psychiatry 20080201 |
Evaluation of drugs for treatment of prion infections of the central nervous system. | The Journal of general virology 20080201 |
History of neuroprotection and rationale as a therapy for glaucoma. | The American journal of managed care 20080201 |
Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial. | Current Alzheimer research 20080201 |
Pharmacologic management of Alzheimer disease. | The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20080201 |
Memantine treatment in patients with mild to moderate Alzheimer's disease: results of a randomised, double-blind, placebo-controlled 6-month study. | Journal of Alzheimer's disease : JAD 20080201 |
Effect of tacrine, amiridine, akatinol memantine, and triazolam on phosphorylation, structure, and assembly of microtubules from brain microtubular proteins in Alzheimer diseases. | Bulletin of experimental biology and medicine 20080201 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. | Journal of medicinal chemistry 20080124 |
Testing NMDA receptor block as a therapeutic strategy for reducing ischaemic damage to CNS white matter. | Glia 20080115 |
Some treatment dilemmas in rapidly developing dementia: a case report. | The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20080101 |
Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. | The Journal of physiology 20080101 |
Memantine prevents MDMA-induced neurotoxicity. | Neurotoxicology 20080101 |
The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells. | Neurochemistry international 20080101 |
Efficacy of memantine on behavioral and psychological symptoms related to dementia: a systematic meta-analysis. | The Annals of pharmacotherapy 20080101 |
Acute treatment with low doses of memantine does not impair aversive, non-associative and recognition memory in rats. | Naunyn-Schmiedeberg's archives of pharmacology 20080101 |
NMDA receptor blockade: a novel avenue for tobacco intervention? | Medical hypotheses 20080101 |
Memantine in major depression with catatonic features. | The Journal of neuropsychiatry and clinical neurosciences 20080101 |
Glutamatergic approaches to the treatment of cognitive and behavioural symptoms of Alzheimer's disease. | Neuro-degenerative diseases 20080101 |
Interaction of memantine and ketamine in morphine- and pentazocine-induced antinociception in mice. | Pharmacological reports : PR 20080101 |
Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: an open-label, crossover, single-centre study. | Clinical drug investigation 20080101 |
[Features of memantine action profile in cholinergic deficit and intracerebral posttraumatic hematoma (hemorrhagic stroke) models in rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20080101 |
Memantine therapy for Alzheimer disease in real-world practice: an observational study in a large representative sample of French patients. | Alzheimer disease and associated disorders 20080101 |
Factors affecting usage patterns of memantine in Alzheimer disease. | Alzheimer disease and associated disorders 20080101 |
Memantine for the treatment of Alzheimer's disease: tolerability and safety data from clinical trials. | Drug safety 20080101 |
[Efficacy and safety of memantine in dementia with Lewy bodies]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101 |
Long-term course and effectiveness of combination therapy in Alzheimer disease. | Alzheimer disease and associated disorders 20080101 |
The use of truncated area under the curves in the bioequivalence evaluation of long half-life drugs. Studies with donepezil and memantine. | Arzneimittel-Forschung 20080101 |
Symptomatic therapeutic aspects in Alzheimer's disease. | Handbook of clinical neurology 20080101 |
Behavioral effects of current Alzheimer's disease treatments: a descriptive review. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20080101 |
[Pathogenetic therapy of spasticity]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101 |
Memantine potentiates agonist-induced Ca2+ responses in HEK 293 cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
Memantine protects against secondary neuronal degeneration in lateral geniculate nucleus and superior colliculus after retinal damage in mice. | CNS neuroscience & therapeutics 20080101 |
Evaluation of the impact of memantine treatment initiation on psychotropics use: a study from the French national health care database. | Neuroepidemiology 20080101 |
[Therapy of Alzheimer's disease: current status and future development]. | Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20080101 |
Treatment of alcohol dependence in patients with co-morbid major depressive disorder--predictors for the outcomes with memantine and escitalopram medication. | Substance abuse treatment, prevention, and policy 20080101 |
Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma. | Progress in brain research 20080101 |
[Memantine (akatinol) therapy of cognitive impairment in Parkinson's disease complicated by dementia]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101 |
[Efficacy of memantine in Parkinson's disease with dementia]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101 |
Discontinuing Alzheimer's disease drug therapy: why, when, and how. | Director (Cincinnati, Ohio) 20080101 |
[Effect of memantine treatment on patients with moderate-to-severe Alzheimer's disease treated with donepezil]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101 |
The uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist memantine prolongs spatial memory in a rat delayed radial-arm maze memory task. | European journal of pharmacology 20071201 |
Memantine normalizes brain activity in the inferior frontal gyrus: a controlled pilot fMRI study. | Schizophrenia research 20071201 |
Effectiveness of open-label donepezil treatment in patients with Alzheimer's disease discontinuing memantine monotherapy. | Current medical research and opinion 20071201 |
[Practical clinical use of therapeutic agents for Alzheimer's disease]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20071201 |
Memantine acts as a cholinergic stimulant in the mouse hippocampus. | Journal of Alzheimer's disease : JAD 20071201 |
The role of glutamate in mood disorders: results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects. | Current psychiatry reports 20071201 |
Expression of N-methyl-d-aspartate receptor 1 in rats with chronic ocular hypertension. | Neuroscience 20071123 |
Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system--too little activation is bad, too much is even worse. | Neuropharmacology 20071101 |
Effect of memantine on neuroretinal function and retinal vascular changes of streptozotocin-induced diabetic rats. | Investigative ophthalmology & visual science 20071101 |
Incidence of cholinergic and memantine treatment in Alzheimer's disease in Finland. | Journal of the American Geriatrics Society 20071101 |
Weight-loss associated with anti-dementia drugs in a patient with Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20071015 |
A pilot study of the clinical efficacy and safety of memantine for Huntington's disease. | Parkinsonism & related disorders 20071001 |
[Management of Alzheimer disease]. | Presse medicale (Paris, France : 1983) 20071001 |
Memantine and recognition memory: possible facilitation of its behavioral effects by the nitric oxide (NO) donor molsidomine. | European journal of pharmacology 20071001 |
Memantine reduces neuronal dysfunctions triggered by in vitro ischemia and 3-nitropropionic acid. | Experimental neurology 20071001 |
A comparison of the binding profiles of dextromethorphan, memantine, fluoxetine and amitriptyline: treatment of involuntary emotional expression disorder. | Experimental neurology 20071001 |
Pathologically activated therapeutics for neuroprotection. | Nature reviews. Neuroscience 20071001 |
Diagnosis and management of vascular cognitive impairment. | Current atherosclerosis reports 20071001 |
[Are anti-dementia drugs worthwhile?]. | MMW Fortschritte der Medizin 20070913 |
Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study. | AIDS (London, England) 20070912 |
New method for high-performance liquid chromatographic determination of amantadine and its analogues in rat plasma. | Journal of pharmaceutical and biomedical analysis 20070903 |
Design, synthesis, and biological evaluation of tricyclic heterocycle-tetraamine conjugates as potent NMDA channel blockers. | Bioorganic & medicinal chemistry letters 20070901 |
Agonist concentration dependency of blocking kinetics but not equilibrium block of N-methyl-D-aspartate receptors by memantine. | Neuropharmacology 20070901 |
Alzheimer's disease: will advances made in the past turn the tide? | The Annals of pharmacotherapy 20070901 |
Efficacy and adverse effects of cholinesterase inhibitors and memantine in vascular dementia: a meta-analysis of randomised controlled trials. | The Lancet. Neurology 20070901 |
Memantine for prevention of migraine: a retrospective study of 60 cases. | The journal of headache and pain 20070901 |
Animal behavior case of the month. Canine compulsive disorder. | Journal of the American Veterinary Medical Association 20070815 |
Memantine produces modest reductions in heroin-induced subjective responses in human research volunteers. | Psychopharmacology 20070801 |
Memantine inhibits ATP-dependent K+ conductances in dopamine neurons of the rat substantia nigra pars compacta. | The Journal of pharmacology and experimental therapeutics 20070801 |
Exacerbation of myoclonus by memantine in a patient with Alzheimer disease. | Journal of clinical psychopharmacology 20070801 |
Treating autism pharmacologically: also tacrine might improve symptomatology in some cases. | Journal of child neurology 20070801 |
Memantine-induced decompensation in a patient with lewy body dementia. | Annals of the Academy of Medicine, Singapore 20070801 |
Cost-effectiveness of memantine compared with standard care in moderate-to-severe Alzheimer disease in Canada. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20070801 |
Comparative study of preventive and therapeutic effects of IEM-1966 and memantine in rats with experimental allergic encephalomyelitis. | Bulletin of experimental biology and medicine 20070801 |
Inhibition of the alpha9alpha10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl-D-aspartate receptors. | European journal of pharmacology 20070702 |
Effects of NMDA receptor antagonists on visceromotor reflexes and on intestinal motility, in vivo. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070701 |
Memantine treatment in patients with mild to moderate Alzheimer's disease: results of a randomised, double-blind, placebo-controlled 6-month study. | Journal of Alzheimer's disease : JAD 20070701 |
Memantine-associated reversal of clozapine-induced weight gain. | Pharmacopsychiatry 20070701 |
Memantine reduces oxidative damage and enhances long-term recognition memory in aged rats. | Neuroscience 20070608 |
High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands. | Brain research 20070602 |
Preclinical investigation of the functional effects of memantine and memantine combined with galantamine or donepezil. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070601 |
Glutamate antagonists seem to be slightly effective in psychopharmacologic treatment of autism. | Journal of clinical psychopharmacology 20070601 |
[Use of specific drugs for Alzheimer's disease]. | Neurologia (Barcelona, Spain) 20070601 |
The effects of acute pretreatment with high-dose memantine on the cardiovascular and behavioral effects of cocaine in humans. | Experimental and clinical psychopharmacology 20070601 |
Successful treatment of Parkinson disease with memantine. | Southern medical journal 20070601 |
Effects of NMDA receptor antagonist memantine on mismatch negativity. | Brain research bulletin 20070530 |
[Frequently occurring forms of dizziness and their treatment]. | MMW Fortschritte der Medizin 20070521 |
NMDA receptor antagonists: tools in neuroscience with promise for treating CNS pathologies. | The Journal of physiology 20070515 |
Effect of memantine and CNQX in the acquisition, expression and reinstatement of cocaine-induced conditioned place preference. | Progress in neuro-psychopharmacology & biological psychiatry 20070509 |
Visual hallucinations and agitation in Alzheimer's disease due to memantine: report of three cases. | Journal of neurology, neurosurgery, and psychiatry 20070501 |
A double-blind, placebo-controlled trial of memantine in age-associated memory impairment (memantine in AAMI). | International journal of geriatric psychiatry 20070501 |
Effects of pan- and subtype-selective N-methyl-D-aspartate receptor antagonists on cortical spreading depression in the rat: therapeutic potential for migraine. | The Journal of pharmacology and experimental therapeutics 20070501 |
Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase. | Molecular pharmacology 20070501 |
The after-effect of human theta burst stimulation is NMDA receptor dependent. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20070501 |
A pilot double-blind treatment trial of memantine for alcohol dependence. | Alcoholism, clinical and experimental research 20070501 |
Investigational treatment for vascular cognitive impairment. | Expert opinion on investigational drugs 20070501 |
Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylation. | Current drug targets 20070501 |
Cost-effectiveness of memantine in moderate-to-severe Alzheimer's disease patients receiving donepezil. | Current medical research and opinion 20070501 |
Therapies for Alzheimer's disease. | Nature reviews. Drug discovery 20070501 |
Postmortem memantine concentrations. | Journal of analytical toxicology 20070501 |
Memantine as adjunctive therapy in children diagnosed with autistic spectrum disorders: an observation of initial clinical response and maintenance tolerability. | Journal of child neurology 20070501 |
Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. | The Journal of biological chemistry 20070413 |
Continuous brachial plexus blockade in combination with the NMDA receptor antagonist memantine prevents phantom pain in acute traumatic upper limb amputees. | European journal of pain (London, England) 20070401 |
Determination of memantine in human plasma by liquid chromatography-electrospray tandem mass spectrometry: application to a bioequivalence study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401 |
Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam. | Alcoholism, clinical and experimental research 20070401 |
Failure to improve the effect of thrombolysis by memantine in a rat embolic stroke model. | Neurological research 20070401 |
[Synthesis and neuroprotective activity in cell culture of aminoadamantane analogues]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070401 |
Serendipitous improvement in the Yips associated with memantine use. | Movement disorders : official journal of the Movement Disorder Society 20070315 |
A retrospective study of memantine in children and adolescents with pervasive developmental disorders. | Psychopharmacology 20070301 |
Memantine fails to facilitate partial cigarette deprivation in smokers--no role of Memantine in the treatment of nicotine dependency? | Journal of neural transmission (Vienna, Austria : 1996) 20070301 |
Neuronal oxidative injury and dendritic damage induced by carbofuran: protection by memantine. | Toxicology and applied pharmacology 20070301 |
Safety and tolerability of once-daily versus twice-daily memantine: a randomised, double-blind study in moderate to severe Alzheimer's disease. | International journal of geriatric psychiatry 20070301 |
Treatment strategies for the behavioral symptoms of Alzheimer's disease: focus on early pharmacologic intervention. | Pharmacotherapy 20070301 |
Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice. | Investigative ophthalmology & visual science 20070301 |
Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients. | The American journal of psychiatry 20070301 |
Open label, multicenter, 28-week extension study of the safety and tolerability of memantine in patients with mild to moderate Alzheimer's disease. | Journal of neurology 20070301 |
Aripiprazole worsening positive symptoms and memantine reducing negative symptoms in a patient with paranoid schizophrenia. | Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20070301 |
Different conclusions about memantine. | Canadian family physician Medecin de famille canadien 20070301 |
NMDA receptor-mediated excitotoxicity contributes to the cerebral hypoxic injury of a rat model of posthypoxic myoclonus. | Brain research 20070216 |
Structure-activity relationships of pentacycloundecylamines at the N-methyl-d-aspartate receptor. | Bioorganic & medicinal chemistry 20070201 |
Memantine in the treatment of mild-to-moderate Alzheimer's disease. | Expert opinion on pharmacotherapy 20070201 |
A brief review of the pharmacologic and therapeutic aspects of memantine in Alzheimer's disease. | Expert opinion on drug metabolism & toxicology 20070201 |
Congenital nystagmus: randomized, controlled, double-masked trial of memantine/gabapentin. | Annals of neurology 20070201 |
Anti-Alzheimer drugs: life-threatening adverse effects. | Prescrire international 20070201 |
A pilot evaluation of the safety, tolerability, pharmacokinetics, and effectiveness of memantine in pediatric patients with attention-deficit/hyperactivity disorder combined type. | Journal of child and adolescent psychopharmacology 20070201 |
Combined neuroprotective effects of celecoxib and memantine in experimental intracerebral hemorrhage. | Neuroscience letters 20070116 |
Memantine as a neuroprotective agent in early phases of psychosis. | Medical hypotheses 20070101 |
Effects of ionotropic glutamate receptor channel blockers on the development of pentylenetetrazol kindling in mice. | Neuroscience and behavioral physiology 20070101 |
Glutamate-modulating drugs & the treatment of mental disorders. | Journal of psychosocial nursing and mental health services 20070101 |
[Akatinol memantine in the therapy of cognitive disorders in Parkinson's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101 |
Memantine treatment of complex regional pain syndrome: a preliminary report of six cases. | The Clinical journal of pain 20070101 |
Memantine treatment of cognitive symptoms in mild to moderate Alzheimer disease: secondary analyses from a placebo-controlled randomized trial. | Alzheimer disease and associated disorders 20070101 |
Domain-specific improvement of cognition on memantine in patients with Alzheimer's disease treated with rivastigmine. | Dementia and geriatric cognitive disorders 20070101 |
Primary progressive aphasia. | Cleveland Clinic journal of medicine 20070101 |
Memantine in the treatment of dementia. | Neuroepidemiology 20070101 |
Memantine in moderate to severe Alzheimer's disease: a meta-analysis of randomised clinical trials. | Dementia and geriatric cognitive disorders 20070101 |
A 24-week randomized, controlled trial of memantine in patients with moderate-to-severe Alzheimer disease. | Alzheimer disease and associated disorders 20070101 |
Memantine for behavioral disturbances in frontotemporal dementia: a case series. | Alzheimer disease and associated disorders 20070101 |
An open-label, flexible-dose study of memantine in major depressive disorder. | Clinical neuropharmacology 20070101 |
Memantine pharmacotherapy: a naturalistic study using a population pharmacokinetic approach. | Clinical pharmacokinetics 20070101 |
Treatment of Alzheimer's disease: the role of symptomatic agents in an era of disease-modifying therapies. | Reviews in neurological diseases 20070101 |
Memantine (Ebixa) in clinical practice - results of an observational study. | Dementia and geriatric cognitive disorders 20070101 |
Analysis of the effect of memantine in reducing the worsening of clinical symptoms in patients with moderate to severe Alzheimer's disease. | Dementia and geriatric cognitive disorders 20070101 |
Pilot trial of memantine in the treatment of posttraumatic stress disorder. | Psychiatry 20070101 |
Reduction of phosphorylated tau during memantine treatment of Alzheimer's disease. | Dementia and geriatric cognitive disorders 20070101 |
A novel class of amino-alkylcyclohexanes as uncompetitive, fast, voltage-dependent, N-methyl-D-aspartate (NMDA) receptor antagonists--in vitro characterization. | Journal of neural transmission (Vienna, Austria : 1996) 20070101 |
Modelling disease progression in Alzheimer's disease: a review of modelling methods used for cost-effectiveness analysis. | PharmacoEconomics 20070101 |
Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity. | The Journal of neuropsychiatry and clinical neurosciences 20070101 |
[Alzheimer Disease]. | Canadian family physician Medecin de famille canadien 20070101 |
[Alzheimer drugs for mild cognitive impairment]. | Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20070101 |
[Combined blockade of GluR1 AMPA and NMDA receptors effectively eliminates neurological disorders in rats with experimental allergic encephalomyelitis]. | Eksperimental'naia i klinicheskaia farmakologiia 20070101 |
Memantine as an example of a fast, voltage-dependent, open channel N-methyl-D-aspartate receptor blocker. | Methods in molecular biology (Clifton, N.J.) 20070101 |
[Neuroprotection in glaucoma]. | Annales Academiae Medicae Stetinensis 20070101 |
In vitro galantamine-memantine co-application: mechanism of beneficial action. | Neuropharmacology 20061201 |
Pharmacokinetics and disposition of memantine in the arterially perfused bovine eye. | Pharmaceutical research 20061201 |
Salicylate- and quinine-induced tinnitus and effects of memantine. | Acta oto-laryngologica. Supplementum 20061201 |
Clock drawing and frontal lobe behavioral effects of memantine in Alzheimer's disease: a rater-blinded study. | American journal of Alzheimer's disease and other dementias 20061201 |
Memantine reduces striatal cell death with decreasing calpain level in 3-nitropropionic model of Huntington's disease. | Brain research 20061106 |
Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat. | Neuroscience 20061103 |
Treatment of dementia: anything new? | Current opinion in psychiatry 20061101 |
Cholinesterase inhibitors and memantine have a role in the treatment of Alzheimer's disease. | Nature clinical practice. Neurology 20061101 |
Clinical practice with anti-dementia drugs: a consensus statement from British Association for Psychopharmacology. | Journal of psychopharmacology (Oxford, England) 20061101 |
Evaluation of clinically relevant glutamate pathway inhibitors in in vitro model of Huntington's disease. | Neuroscience letters 20061030 |
Cognitive dysfunction induced by sequential injection of amyloid-beta and ibotenate into the bilateral hippocampus; protection by memantine and MK-801. | European journal of pharmacology 20061024 |
Shift shown in influenza A adamantane resistance. | JAMA 20061004 |
[Medical treatment of Alzheimer's disease]. | Ugeskrift for laeger 20061002 |
[Retrospective comparative analysis of antidementia medication persistence patterns in Spanish Alzheimer's disease patients treated with donepezil, rivastigmine, galantamine and memantine]. | Revista de neurologia 20061001 |
Use of antidementia agents in vascular dementia: beyond Alzheimer disease. | Mayo Clinic proceedings 20061001 |
Enhancement of long-term spatial memory in adult rats by the noncompetitive NMDA receptor antagonists, memantine and neramexane. | Pharmacology, biochemistry, and behavior 20061001 |
A prospective, open-label trial of memantine in the treatment of cognitive, behavioral, and memory dysfunction in pervasive developmental disorders. | Journal of child and adolescent psychopharmacology 20061001 |
Behavioral effects of aminoadamantane class NMDA receptor antagonists on schedule-induced alcohol and self-administration of water in mice. | Psychopharmacology 20060901 |
Altered synaptic function in Alzheimer's disease. | European journal of pharmacology 20060901 |
New pathways in drug discovery for Alzheimer's disease. | Current neurology and neuroscience reports 20060901 |
Potential role of N-methyl-D-aspartate receptors as executors of neurodegeneration resulting from diverse insults: focus on memantine. | Behavioural pharmacology 20060901 |
Shedding light on Alzheimer's. | The Nurse practitioner 20060901 |
From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20060901 |
Memantine may acutely improve cognition and have a mood stabilizing effect in treatment-resistant bipolar disorder. | Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20060901 |
Memantine augmentation for refractory obsessive-compulsive disorder. | Progress in neuro-psychopharmacology & biological psychiatry 20060830 |
Use of memantine to treat Alzheimer's disease. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060829 |
[Advances in Alzheimer's disease treatment]. | La Revue de medecine interne 20060801 |
Memantine treatment in mild to moderate Alzheimer disease: a 24-week randomized, controlled trial. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20060801 |
Clinical experience with risperidone and memantine in the treatment of Huntington's disease. | Journal of the National Medical Association 20060801 |
A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy. | Journal of neurovirology 20060801 |
Behavioral effects of memantine in Alzheimer disease patients receiving donepezil treatment. | Neurology 20060711 |
Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine. | FEBS letters 20060710 |
Nitrous oxide and xenon prevent amphetamine-induced carrier-mediated dopamine release in a memantine-like fashion and protect against behavioral sensitization. | Biological psychiatry 20060701 |
The effects of gabapentin and memantine in acquired and congenital nystagmus: a retrospective study. | The British journal of ophthalmology 20060701 |
Pharmacology of acetylcholinesterase inhibitors and N-methyl-D-aspartate receptors for combination therapy in the treatment of Alzheimer's disease. | Journal of clinical pharmacology 20060701 |
Rationale for combination therapy with galantamine and memantine in Alzheimer's disease. | Journal of clinical pharmacology 20060701 |
Clinically relevant pharmacology of neuropsychiatric drugs approved over the last three years: part I. | Journal of psychiatric practice 20060701 |
Dementia with lewy bodies: therapeutic opportunities and pitfalls. | The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20060701 |
Cost-effectiveness of memantine in community-based Alzheimer's disease patients: An adaptation in Spain. | The European journal of health economics : HEPAC : health economics in prevention and care 20060601 |
Alzheimer's disease: beware of interactions with cholinesterase inhibitors. | Prescrire international 20060601 |
Memantine: the next trend in academic performance enhancement? | The Journal of the American Osteopathic Association 20060601 |
The synergistic effect of selective sigma receptor agonists and uncompetitive NMDA receptor antagonists in the forced swim test in rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060601 |
Memantine for disruptive behavior in autistic disorder. | The Journal of clinical psychiatry 20060601 |
[Memantine and Complex Regional Pain Syndrome (CRPS): effects of treatment and cortical reorganisation]. | Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... 20060601 |
[Anti-dementia drugs for dementia syndromes--just unkept promises?]. | MMW Fortschritte der Medizin 20060515 |
Memantine, an uncompetitive low affinity NMDA open-channel antagonist improves clinical rating scores in a multiple infarct embolic stroke model in rabbits. | Brain research 20060509 |
Simultaneous liquid chromatographic assay of amantadine and its four related compounds in phosphate-buffered saline using 4-fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorescent derivatization reagent. | Biomedical chromatography : BMC 20060501 |
A responder analysis of memantine treatment in patients with Alzheimer disease maintained on donepezil. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20060501 |
[Glutamate-related excitotoxicity neuroprotection with memantine, an uncompetitive antagonist of NMDA-glutamate receptor, in Alzheimer's disease and vascular dementia]. | Revista de neurologia 20060501 |
What's new in clinical pharmacology and therapeutics. | WMJ : official publication of the State Medical Society of Wisconsin 20060501 |
Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity. | The European journal of neuroscience 20060501 |
Memantine for dementia. | The Cochrane database of systematic reviews 20060419 |
[The practice guideline 'Diagnosis and pharmaceutical treatment of dementia']. | Nederlands tijdschrift voor geneeskunde 20060415 |
Low doses of memantine disrupt memory in adult rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060412 |
Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice. | Behavioural brain research 20060403 |
Memantine reduces hematoma expansion in experimental intracerebral hemorrhage, resulting in functional improvement. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060401 |
Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice. | The Journal of pharmacology and experimental therapeutics 20060401 |
Effects of memantine, haloperidol, and cocaine on primary and conditioned reinforcement associated with cocaine in rhesus monkeys. | Psychopharmacology 20060401 |
[New therapeutic options in Alzheimer's disease]. | Revista de neurologia 20060401 |
Visual hallucinations from the addition of riluzole to memantine and bupropion. | Journal of clinical psychopharmacology 20060401 |
[Clinical efficacy and safety of akatinol memantine in treatment of mild to moderate Alzheimer disease: a donepezil-controlled, randomized trial]. | Zhonghua nei ke za zhi 20060401 |
Changes in cerebral neurotransmitters and metabolites induced by acute donepezil and memantine administrations: a microdialysis study. | Brain research bulletin 20060331 |
Effects of memantine on estrogen-dependent acute tolerance to the morphine analgesia in female rats. | European journal of pharmacology 20060327 |
Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice. | Neuroscience letters 20060306 |
In vivo regulation of GSK3 phosphorylation by cholinergic and NMDA receptors. | Neurobiology of aging 20060301 |
[The action of memantine on the cognitive disorders of patients with dementia: reflections following two years' experience in Spain]. | Revista de neurologia 20060301 |
Nationwide use of medicines for Alzheimer's disease by community-dwelling persons in Finland. | Journal of the American Geriatrics Society 20060301 |
Observations from a 14-week open-label trial with memantine suggest variable response on behavioral symptoms and cognition, depending on former treatment of AD. | International psychogeriatrics 20060301 |
Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells. | Neuroscience letters 20060220 |
Effects of pharmacologically induced changes in NMDA receptor activity on human timing and sensorimotor performance. | Brain research 20060216 |
[New options for the pharmacotherapy of Alzheimer disease after the approval of memantine? Re the article from DMW 8/2005]. | Deutsche medizinische Wochenschrift (1946) 20060210 |
Mechanism of action of memantine. | Current opinion in pharmacology 20060201 |
Catatonic schizophrenia and the use of memantine. | The Annals of pharmacotherapy 20060201 |
Glutamate receptors on human melanocytes regulate the expression of MiTF. | Pigment cell research 20060201 |
Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. | Nature reviews. Drug discovery 20060201 |
Alzheimer's treatment in nursing homes: room for improvement. | Journal of the American Medical Directors Association 20060201 |
Dementia assessment and management. | Journal of the American Medical Directors Association 20060201 |
Memantine protects neurons from shrinkage in the lateral geniculate nucleus in experimental glaucoma. | Archives of ophthalmology (Chicago, Ill. : 1960) 20060201 |
[Long-term effects of memantine therapy on neonatal rats with hypoxic-ischemic brain damage]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20060201 |
I remember. | Canadian family physician Medecin de famille canadien 20060201 |
Memantine attenuates staurosporine-induced activation of caspase-3 and LDH release in mouse primary neuronal cultures. | Brain research 20060119 |
Reinstatement of morphine-conditioned reward is blocked by memantine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060101 |
Cognitive evaluation of disease-modifying efficacy of galantamine and memantine in the APP23 model. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060101 |
Alarming arbitrariness in EU prescription and reimbursement criteria for anti-dementia drugs. | International journal of geriatric psychiatry 20060101 |
A double-blind, placebo-controlled study of memantine in the treatment of major depression. | The American journal of psychiatry 20060101 |
What we can learn from open-label extensions of randomized clinical trials. | Archives of neurology 20060101 |
A 24-week open-label extension study of memantine in moderate to severe Alzheimer disease. | Archives of neurology 20060101 |
Rivastigmine monotherapy and combination therapy with memantine in patients with moderately severe Alzheimer's disease who failed to benefit from previous cholinesterase inhibitor treatment. | International journal of clinical practice 20060101 |
The clinical and cost-effectiveness of donepezil, rivastigmine, galantamine and memantine for Alzheimer's disease. | Health technology assessment (Winchester, England) 20060101 |
Pharmacokinetic study of memantine in healthy and renally impaired subjects. | Clinical pharmacology and therapeutics 20060101 |
Memantine increases cardiovascular but not behavioral effects of cocaine in methadone-maintained humans. | Pharmacology, biochemistry, and behavior 20060101 |
Possible role of excitotoxicity in the pathogenesis of glaucoma. | Clinical & experimental ophthalmology 20060101 |
Nurses warn Alzheimer's drugs ban will lead to more sedation. | Nursing times 20060101 |
Efficacy and safety of memantine in moderate-to-severe Alzheimer disease: the evidence to date. | Alzheimer disease and associated disorders 20060101 |
Managing discontinuation syndrome in patients with dementia. | Journal of psychiatry & neuroscience : JPN 20060101 |
[Open angle glaucoma: epidemiology, pathogenesis and prevention]. | Recenti progressi in medicina 20060101 |
A systematic review of the clinical and cost-effectiveness of memantine in patients with moderately severe to severe Alzheimer's disease. | Drugs & aging 20060101 |
Neuropathologic changes in Alzheimer's disease: potential targets for treatment. | The Journal of clinical psychiatry 20060101 |
Navigating patients and caregivers through the course of Alzheimer's disease. | The Journal of clinical psychiatry 20060101 |
Contemporary issues in the treatment of Alzheimer's disease: tangible benefits of current therapies. | The Journal of clinical psychiatry 20060101 |
Neuroprotection in vascular dementia. | Cerebrovascular diseases (Basel, Switzerland) 20060101 |
Amantadine and memantine in catatonic schizophrenia. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20060101 |
Magnesium supplementation in the treatment of dementia patients. | Medical hypotheses 20060101 |
3-Nitropropionic acid toxicity in hippocampus: protection through N-methyl-D-aspartate receptor antagonism. | Hippocampus 20060101 |
Memantine: a review of its use in Alzheimer's disease. | Drugs 20060101 |
Treatment effect size of memantine therapy in Alzheimer disease and vascular dementia. | Alzheimer disease and associated disorders 20060101 |
[Pharmacotherapy for Alzheimer's disease]. | Tijdschrift voor psychiatrie 20060101 |
Realistic expectations for treatment success in Alzheimer's disease. | The journal of nutrition, health & aging 20060101 |
Effect of BD 1047, a sigma1 receptor antagonist, in the animal models predictive of antipsychotic activity. | Pharmacological reports : PR 20060101 |
Disease-modifying therapies in Alzheimer's disease: how far have we come? | Drugs 20060101 |
Alzheimer disease and its management: a review. | American journal of therapeutics 20060101 |
Cognitive response to memantine in moderate to severe Alzheimer disease patients already receiving donepezil: an exploratory reanalysis. | Alzheimer disease and associated disorders 20060101 |
Activities of daily living in moderate-to-severe Alzheimer disease: an analysis of the treatment effects of memantine in patients receiving stable donepezil treatment. | Alzheimer disease and associated disorders 20060101 |
Added therapeutic value of memantine in the treatment of moderate to severe Alzheimer's disease. | Clinical drug investigation 20060101 |
Comparison of donepezil and memantine for protective effect against amyloid-beta(1-42) toxicity in rat septal neurons. | Neuroscience letters 20051231 |
Topical and systemic drug delivery to the posterior segments. | Advanced drug delivery reviews 20051213 |
[Efficacy of memantine in the treatment of Alzheimer's disease]. | Neurologia (Barcelona, Spain) 20051201 |
Exacerbation of Lewy bodies dementia due to memantine. | Journal of Alzheimer's disease : JAD 20051201 |
Dementia. | Clinical evidence 20051201 |
Drugs for Alzheimer disease. | Canadian family physician Medecin de famille canadien 20051110 |
Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model. | The European journal of neuroscience 20051101 |
Memantine for treatment-resistant OCD. | The American journal of psychiatry 20051101 |
Rationalizing therapeutic approaches in Alzheimer's disease. | CNS spectrums 20051101 |
[Little behavior improvement with memantine]. | Medizinische Monatsschrift fur Pharmazeuten 20051101 |
[Effects of blockade of ionotropic glutamate receptors on the development of pentylenetetrazole kindling in mice]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20051101 |
Interaction between neurotransmitter antagonists and effects of sacral neuromodulation in rats with chronically hyperactive bladder. | BJU international 20051001 |
Treatment approaches to symptoms associated with frontotemporal degeneration. | Current psychiatry reports 20051001 |
Memantine: a therapeutic approach in treating Alzheimer's and vascular dementia. | Current drug targets. CNS and neurological disorders 20051001 |
Investigation of the pharmacokinetic and pharmacodynamic interactions between memantine and glyburide/metformin in healthy young subjects: a single-center, multiple-dose, open-label study. | Clinical therapeutics 20051001 |
Anti-allodynic interactions between NMDA receptor channel blockers and morphine or clonidine in neuropathic rats. | European journal of pharmacology 20050905 |
Pharmacological implications of two distinct mechanisms of interaction of memantine with N-methyl-D-aspartate-gated channels. | The Journal of pharmacology and experimental therapeutics 20050901 |
Antipsychotic dose-sparing effect with addition of memantine. | The Annals of pharmacotherapy 20050901 |
Spontaneous bruising as a possible adverse reaction to memantine. | Internal medicine journal 20050901 |
UK government guidance on Alzheimer's drugs postponed. | Drug discovery today 20050901 |
[Memantine as an adjunctive therapy for schizophrenia negative symptoms]. | Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20050901 |
Memantine inhibits ethanol-induced NMDA receptor up-regulation in rat hippocampal neurons. | Brain research 20050809 |
Delusions and hallucinations in dementia with Lewy bodies: worsening with memantine. | Neurology 20050809 |
An evaluation of the reinforcing effects of memantine in cocaine-dependent humans. | Drug and alcohol dependence 20050801 |
The use of memantine in dementia with Lewy bodies. | Journal of Alzheimer's disease : JAD 20050801 |
Effects of memantine and donepezil on amyloid beta-induced memory impairment in a delayed-matching to position task in rats. | Behavioural brain research 20050730 |
Memantine for dementia. | The Cochrane database of systematic reviews 20050720 |
A new anti-obesity drug treatment: first clinical evidence that, antagonising glutamate-gated Ca2+ ion channels with memantine normalises binge-eating disorders. | Economics and human biology 20050701 |
[Pharmacological therapy in Alzheimer's disease. Current clinical practice in The Netherlands]. | Tijdschrift voor gerontologie en geriatrie 20050701 |
Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model. | Psychopharmacology 20050601 |
Combination drug therapies for AD: progress is slow, but we must keep trying. | Geriatrics 20050601 |
Combination drug therapy for Alzheimer's disease: what is evidence-based, and what is not? | Geriatrics 20050601 |
Measuring treatment response in Alzheimer's disease clinical trials. | Geriatrics 20050601 |
Mild cognitive impairment and preclinical Alzheimer's disease. | Geriatrics 20050601 |
Refining treatment guidelines in Alzheimer's disease. | Geriatrics 20050601 |
Cost-effectiveness of memantine for moderate to severe Alzheimer's disease in Sweden. | The American journal of geriatric pharmacotherapy 20050601 |
N-methyl-D-aspartate receptor in human prostate cancer. | The Journal of membrane biology 20050601 |
[Modern therapy for dementia]. | MMW Fortschritte der Medizin 20050517 |
[Assessment of dementia and use of anti-dementia drugs in nursing homes]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050504 |
Comments on 'Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than N-methyl-D-aspartate receptors in rat hippocampal neurons'. | The Journal of pharmacology and experimental therapeutics 20050501 |
Steady-state pharmacokinetics of galantamine are not affected by addition of memantine in healthy subjects. | Journal of clinical pharmacology 20050501 |
Effects of memantine on behavioural symptoms in Alzheimer's disease patients: an analysis of the Neuropsychiatric Inventory (NPI) data of two randomised, controlled studies. | International journal of geriatric psychiatry 20050501 |
A comparison of the predictive therapeutic and undesired side-effects of the NMDA receptor antagonist, memantine, in mice. | Behavioural pharmacology 20050501 |
Development of subtle psychotic symptoms with memantine: a case report. | The Journal of clinical psychiatry 20050501 |
Antidementia agents: what is important in this class. | Managed care (Langhorne, Pa.) 20050501 |
Effect of donepezil in patients with Alzheimer's disease previously untreated or treated with memantine or nootropic agents in Germany: an observational study. | Current medical research and opinion 20050501 |
Memantine for dementia. | The Cochrane database of systematic reviews 20050418 |
Drug discrimination analysis of NMDA receptor channel blockers as nicotinic receptor antagonists in rats. | Psychopharmacology 20050401 |
19F and 1H MRI detection of amyloid beta plaques in vivo. | Nature neuroscience 20050401 |
The effects of memantine on lipid peroxidation following closed-head trauma in rats. | Neurosurgical review 20050401 |
Alzheimer disease, in living color. | Nature neuroscience 20050401 |
The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism. | Current Alzheimer research 20050401 |
Simultaneous determination of the binding of amantadine and its analogues to synthetic melanin by liquid chromatography after precolumn derivatization with dansyl chloride. | Journal of chromatographic science 20050401 |
NICE proposes to withdraw Alzheimer's drugs from NHS. | BMJ (Clinical research ed.) 20050305 |
Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons. | The Journal of pharmacology and experimental therapeutics 20050301 |
Carbofuran-induced oxidative stress in slow and fast skeletal muscles: prevention by memantine and atropine. | Toxicology 20050301 |
Memantine and catatonic schizophrenia. | The American journal of psychiatry 20050301 |
Memantine for treatment of moderate to severe Alzheimer's disease. | Issues in emerging health technologies 20050301 |
Is there a double standard when it comes to dementia care? | International journal of clinical practice. Supplement 20050301 |
Memantine alleviates toxicity induced by dichlorvos in rats. | Journal of occupational health 20050301 |
[Pharmacological treatment in severe dementia]. | Psychologie & neuropsychiatrie du vieillissement 20050301 |
Pharmacologic treatment options in Alzheimer's disease: optimizing disease management. | Journal of the American Academy of Nurse Practitioners 20050301 |
Alzheimer's disease care management plan: maximizing patient care. | Journal of the American Academy of Nurse Practitioners 20050301 |
[New options for the pharmacotherapy of Alzheimer's disease after the registration of memantine?]. | Deutsche medizinische Wochenschrift (1946) 20050225 |
Seizures associated with memantine use. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050215 |
Effect of memantine on the alpha 7 neuronal nicotinic receptors, synaptophysin- and low molecular weight MAP-2 levels in the brain of transgenic mice over-expressing human acetylcholinesterase. | Journal of neural transmission (Vienna, Austria : 1996) 20050201 |
Memantine and progressive glaucoma. | Journal of glaucoma 20050201 |
2004 drug approval highlights: FDA update. | The Nurse practitioner 20050201 |
[Advanced dementia in Alzheimer's disease and memantine]. | Revista de neurologia 20050201 |
Brain but not spinal NR2B receptor is responsible for the anti-allodynic effect of an NR2B subunit-selective antagonist CP-101,606 in a rat chronic constriction injury model. | Pharmacology 20050101 |
Dementia of Alzheimer's disease and other neurodegenerative disorders--memantine, a new hope. | Pharmacological research 20050101 |
Could cholinesterase inhibitors and memantine alleviate HIV dementia? | Journal of acquired immune deficiency syndromes (1999) 20050101 |
The emperor has no clothes: dementia treatment on the eve of the aging era. | Journal of the American Geriatrics Society 20050101 |
Memantine as a neuroprotective treatment in schizophrenia. | The British journal of psychiatry : the journal of mental science 20050101 |
Memantine: a pharmacoeconomic review of its use in moderate-to-severe Alzheimer's disease. | PharmacoEconomics 20050101 |
Another perspective on the memantine graphs: clinical vs. statistical significance. | Medicine and health, Rhode Island 20050101 |
Memantine: targeting glutamate excitotoxicity in Alzheimer's disease and other dementias. | American journal of Alzheimer's disease and other dementias 20050101 |
Effect of NMDA receptor antagonists on behavioral impairment induced by chronic treatment with dexamethasone. | Pharmacological reports : PR 20050101 |
The NMDA antagonist memantine affects training induced motor cortex plasticity--a study using transcranial magnetic stimulation. | BMC neuroscience 20050101 |
Current status and future promise of pharmacotherapeutic strategies for Alzheimer's disease. | Journal of the American Medical Directors Association 20050101 |
[Music and art therapy--a taboo topic in therapy of dementia?]. | Krankenpflege Journal 20050101 |
[Effectiveness and tolerance of memantine in general practice]. | Krankenpflege Journal 20050101 |
Health utilities in Alzheimer's disease and implications for cost-effectiveness analysis. | PharmacoEconomics 20050101 |
NMDA receptor antagonism does not inhibit induction of ischemic tolerance in gerbil brain in vivo. | Neurotoxicity research 20050101 |
Drug therapy of dementia in elderly patients. A review. | Nordic journal of psychiatry 20050101 |
[Mitochondria as the target for neuroprotectors]. | Vestnik Rossiiskoi akademii meditsinskikh nauk 20050101 |
[Use of acetylcholinesterase inhibitors and memantine in Alzheimer-type dementia]. | Revista espanola de salud publica 20050101 |
Guidelines for the treatment of Alzheimer's disease from the Italian Association of Psychogeriatrics. | Drugs & aging 20050101 |
[Also consider non-cognitive disorders]. | Krankenpflege Journal 20050101 |
A multicenter in vivo proton-MRS study of HIV-associated dementia and its relationship to age. | NeuroImage 20041201 |
Paradigm shift in NMDA receptor antagonist drug development: molecular mechanism of uncompetitive inhibition by memantine in the treatment of Alzheimer's disease and other neurologic disorders. | Journal of Alzheimer's disease : JAD 20041201 |
Dementia. | Clinical evidence 20041201 |
Vascular dementia. Advances in nosology, diagnosis, treatment and prevention. | Panminerva medica 20041201 |
Efficacy and tolerability of memantine in the treatment of dementia. | The American journal of geriatric pharmacotherapy 20041201 |
Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease. | The Journal of pharmacology and experimental therapeutics 20041101 |
Memantine for dementia. | The Cochrane database of systematic reviews 20041018 |
Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones. | British journal of pharmacology 20041001 |
Inhibitory effects of memantine on human cytochrome P450 activities: prediction of in vivo drug interactions. | European journal of clinical pharmacology 20041001 |
The place of memantine in the treatment of Alzheimer's disease: a number needed to treat analysis. | International journal of geriatric psychiatry 20041001 |
Lack of pharmacokinetic or pharmacodynamic interaction between memantine and donepezil. | The Annals of pharmacotherapy 20040901 |
Co-administration of memantine has no effect on the in vitro or ex vivo determined acetylcholinesterase inhibition of rivastigmine in the rat brain. | Neuropharmacology 20040901 |
Memantine approved to treat moderate to severe Alzheimer's disease. | Current neurology and neuroscience reports 20040901 |
[Memantine: a therapeutic drug for Alzheimer's disease and the comparison with MK-801]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040901 |
The benefits and risks associated with cholinesterase inhibitor therapy in Alzheimer's disease. | Expert opinion on drug safety 20040901 |
Effects of NMDA receptor antagonists (MK-801 and memantine) on the acquisition of morphine-induced conditioned place preference in mice. | Progress in neuro-psychopharmacology & biological psychiatry 20040901 |
Memantine: pharmacological properties and clinical uses. | Neurology India 20040901 |
Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040811 |
[Diagnosis and treatment of vascular dementia]. | Praxis 20040811 |
Effects of low-affinity NMDA receptor channel blockers in two rat models of chronic pain. | Neuropharmacology 20040801 |
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures. | Investigative ophthalmology & visual science 20040801 |
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures. | Investigative ophthalmology & visual science 20040801 |
Cognition and immunity; antibody impairs memory. | Immunity 20040801 |
Memantine hydrochloride: pharmacological and clinical profile. | Drugs of today (Barcelona, Spain : 1998) 20040801 |
[Role of magnesium ions on the regulation of NMDA receptor--a pharmacopathology of memantine]. | Clinical calcium 20040801 |
Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation. | Neuroscience letters 20040722 |
Alzheimer's disease. | The New England journal of medicine 20040701 |
What is the rationale for new treatment strategies in Alzheimer's disease? | CNS spectrums 20040701 |
Understanding the latest advances in pharmacologic interventions for Alzheimer's disease. | CNS spectrums 20040701 |
Effects of NMDA receptor channel blockers, MK-801 and memantine, on locomotor activity and tolerance to delay of reward in Wistar-Kyoto and spontaneously hypertensive rats. | Behavioural pharmacology 20040701 |
The NMDA receptor channel blocker memantine and opioid receptor antagonist naltrexone inhibit the saccharin deprivation effect in rats. | Behavioural pharmacology 20040701 |
Intraarticular pretreatment with ketamine and memantine could prevent arthritic pain: relevance to the decrease of spinal c-fos expression in rats. | Anesthesia and analgesia 20040701 |
[New informations on medical treatment for normal-tension glaucoma]. | Nippon Ganka Gakkai zasshi 20040701 |
[Psychotropic drug treatment in dementia disorders]. | Deutsche medizinische Wochenschrift (1946) 20040618 |
[Effect of drugs against dementia]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20040617 |
[Memantine can relieve certain symptoms in Parkinson disease. Improvement achieved in two out of three described cases with dyskinesia and cognitive failure]. | Lakartidningen 20040603 |
Identification of genes regulated by memantine and MK-801 in adult rat brain by cDNA microarray analysis. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040601 |
New platinum(IV) complex with adamantylamine ligand as a promising anti-cancer drug: comparison of in vitro cytotoxic potential towards A2780/cisR cisplatin-resistant cell line within homologous series of platinum(IV) complexes. | Anti-cancer drugs 20040601 |
Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: implications for the intellectual disability population. | International journal of geriatric psychiatry 20040601 |
NMDA receptor antagonists. A new therapeutic approach for Alzheimer's disease. | Geriatrics 20040601 |
Dementia. | Clinical evidence 20040601 |
Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration. | FEBS letters 20040521 |
Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury. | Bioorganic & medicinal chemistry letters 20040517 |
Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol. | Stroke 20040501 |
American Chemical Society--227th Annual Meeting. NMDA receptor. 28 March - 1 April 2004, Anaheim, CA, USA. | IDrugs : the investigational drugs journal 20040501 |
Memantine enhances autonomy in moderate to severe Alzheimer's disease. | International journal of geriatric psychiatry 20040501 |
Caffeine withdrawal syndrome in social interaction test in mice: effects of the NMDA receptor channel blockers, memantine and neramexane. | Behavioural pharmacology 20040501 |
Pharmacotherapeutic approaches to the treatment of Alzheimer's disease. | Clinical therapeutics 20040501 |
Memantine for patients with Alzheimer disease. | JAMA 20040414 |
[Memantine (Ebixa), glutaminergic modulator]. | Revue medicale de Bruxelles 20040401 |
Memantine (Namenda) for moderate to severe Alzheimer's disease. | American family physician 20040315 |
Questions & answers. We've been told that my wife has multi-infarct dementia and that the new drug memantine may help. How is her condition different from Alzheimer's disease, and what could memantine do for her? | The Harvard mental health letter 20040301 |
Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome. | Pharmacopsychiatry 20040301 |
Acute effects of memantine in combination with alcohol in moderate drinkers. | Psychopharmacology 20040201 |
A placebo-controlled randomized crossover trial of the N-methyl-D-aspartic acid receptor antagonist, memantine, in patients with chronic phantom limb pain. | Anesthesia and analgesia 20040201 |
Effects of NMDA receptor antagonists on olfactory learning and memory in the honeybee (Apis mellifera). | Pharmacology, biochemistry, and behavior 20040201 |
Vascular cognitive impairment. | Stroke 20040201 |
No nerve growth factor response to treatment with memantine in adult rats. | Journal of neural transmission (Vienna, Austria : 1996) 20040201 |
FDA approves groundbreaking Alzheimer's drug. | Provider (Washington, D.C.) 20040201 |
Academic highlights: emerging therapeutic strategies in Alzheimer's disease. | The Journal of clinical psychiatry 20040201 |
Drug for moderate to advanced Alzheimer's approved. | Mayo Clinic health letter (English ed.) 20040201 |
[Protective effect of memantine on N-methyl-D-aspartate receptor in dichlorvos-poisoned rat brain]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20040201 |
Memantine hydrochloride. | Nature reviews. Drug discovery 20040201 |
Scopolamine given pre-Trial 1 prevents the one-trial tolerance phenomenon in the elevated plus-maze Trial 2. | Behavioural pharmacology 20040201 |
[New concepts in the physiopathology of hepatic encephalopathy and therapeutic prospects]. | Gastroenterologia y hepatologia 20040201 |
Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial. | JAMA 20040121 |
Adenosine A2A receptor mRNA expression is increased in rat striatum and nucleus accumbens after memantine administration. | Brain research. Molecular brain research 20040105 |
Paradigm shift in neuroprotective drug development: clinically tolerated NMDA receptor inhibition by memantine. | Cell death and differentiation 20040101 |
Evolutionary rather than revolutionary progress in dementia. | The Lancet. Neurology 20040101 |
NMDA-antagonism (memantine): an alternative pharmacological therapeutic principle in Alzheimer's and vascular dementia. | Current pharmaceutical design 20040101 |
Society of neuroscience-33rd annual meeting: metabotropic glutamate receptors. | IDrugs : the investigational drugs journal 20040101 |
Update on dementia medications for 2004. | Geriatric nursing (New York, N.Y.) 20040101 |
Memantine: an antiglutamatergic option for dementia. | American journal of Alzheimer's disease and other dementias 20040101 |
[Mémantine (Ebixa): a new therapeutic strategy for the treatment of moderate to severe forms of Alzheimer's disease]. | L'Encephale 20040101 |
First drug for moderate-to-severe Alzheimer's. | FDA consumer 20040101 |
The presence of the APP(swe) mutation in mice does not increase the vulnerability of cholinergic basal forebrain neurons to neuroinflammation. | Neuroscience 20040101 |
Chronic memantine does not block 3-nitropropionic acid-delayed ischaemic tolerance in rat hippocampal slices ex vivo. | Neurotoxicity research 20040101 |
Effect of memantine on the levels of glial cells, neuropeptides, and peptide-degrading enzymes in rat brain regions of ibotenic acid-treated alzheimer's disease model. | Neuroscience 20040101 |
Memantine in moderate-to-severe Alzheimer disease evidence and ethics based? | Alzheimer disease and associated disorders 20040101 |
What are the treatment options for patients with severe Alzheimer's disease? | CNS drugs 20040101 |
Specific functional effects of memantine treatment in patients with moderate to severe Alzheimer's disease. | Dementia and geriatric cognitive disorders 20040101 |
Cost effectiveness of memantine in Alzheimer's disease: an analysis based on a probabilistic Markov model from a UK perspective. | Drugs & aging 20040101 |
[The clinical relevance of memantine use]. | Psychiatria polska 20040101 |
The N-methyl-D-aspartate antagonist memantine retards progression of Huntington's disease. | Journal of neural transmission. Supplementum 20040101 |
Memantine: a new approach to Alzheimer's disease. | Perspectives in psychiatric care 20040101 |
Why do many NMDA antagonists fail, while others are safe and effective at blocking excitotoxicity associated with dementia and acute injury? | American journal of Alzheimer's disease and other dementias 20040101 |
Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults. | NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 20040101 |
Treatment of Alzheimer's disease: current and future therapeutic approaches. | Reviews in neurological diseases 20040101 |
Memantine attenuates the increase in striatal preproenkephalin mRNA expression and development of haloperidol-induced persistent oral dyskinesias in rats. | Brain research 20031224 |
Into the darkness of the mind. | Newsweek 20031208 |
Anxiolytic-like effects of NMDA/glycine-B receptor ligands are abolished during the elevated plus-maze trial 2 in rats. | Psychopharmacology 20031201 |
Mechanotransduction by intraganglionic laminar endings of vagal tension receptors in the guinea-pig oesophagus. | The Journal of physiology 20031201 |
Evaluation of memantine for the treatment of Alzheimer's disease. | Expert opinion on pharmacotherapy 20031201 |
Inhibition of human alpha 7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors. | British journal of pharmacology 20031201 |
Erotomania variants in dementia. | Journal of geriatric psychiatry and neurology 20031201 |
New Alzheimer's drug approved. | Health news (Waltham, Mass.) 20031201 |
Alzheimer's disease: a progress report, Part II. The continuing search for treatments and persistent hopes for prevention. | The Harvard mental health letter 20031201 |
Memantine: new preparation. Poor evaluation and uncertain benefit in Alzheimer's disease. | Prescrire international 20031201 |
[Not a subject. Speech and swallowing disorders in dementia]. | MMW Fortschritte der Medizin 20031113 |
[Dementia]. | Fortschritte der Neurologie-Psychiatrie 20031101 |
Memantine (Ebixa) in the later stages of dementia. | Hospital medicine (London, England : 1998) 20031101 |
Comparative study of action mechanisms of dimebon and memantine on AMPA- and NMDA-subtypes glutamate receptors in rat cerebral neurons. | Bulletin of experimental biology and medicine 20031101 |
[Memantine for the treatment of dementia]. | Nederlands tijdschrift voor geneeskunde 20031025 |
Editorial comment--How to treat vascular dementia? | Stroke 20031001 |
Is memantine a breakthrough in the treatment of moderate-to-severe Alzheimer's disease? | Expert opinion on pharmacotherapy 20031001 |
Memantine for dementia? | Drug and therapeutics bulletin 20031001 |
Binding of memantine to melanin: influence of type of melanin and characteristics. | Pharmaceutical research 20031001 |
Memantine presents different effects from MK-801 in motivational and physical signs of morphine withdrawal. | Behavioural brain research 20030915 |
Memantine for Alzheimer's disease. | The Medical letter on drugs and therapeutics 20030915 |
NMDA-mediated mechanisms in cortical excitability changes after limb amputation. | Acta neurologica Scandinavica 20030901 |
Treatment of Alzheimer's disease: current status and new perspectives. | The Lancet. Neurology 20030901 |
The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence. | International journal of geriatric psychiatry 20030901 |
Treating the full spectrum of dementia with memantine. | International journal of geriatric psychiatry 20030901 |
Memantine: update on the current evidence. | International journal of geriatric psychiatry 20030901 |
Does this patient have Alzheimer disease? Diagnosing and treating dementia. | Cleveland Clinic journal of medicine 20030901 |
Diagnosis and management of Alzheimer's disease. | Connecticut medicine 20030901 |
[Antibodies, antihypertensive drugs, antioxidants. Can they prevent Alzheimer disease?]. | MMW Fortschritte der Medizin 20030821 |
Memantine in moderate-to-severe Alzheimer's disease. | The New England journal of medicine 20030807 |
Memantine for the treatment of dementia. | The Lancet. Neurology 20030801 |
Treating the dementia of Iris with a cholinesterase inhibitor. | International journal of geriatric psychiatry 20030801 |
[Glutamate antagonists for treatment of neuropathic pain]. | Schmerz (Berlin, Germany) 20030801 |
[Drug therapy of Alzheimer dementia]. | Ugeskrift for laeger 20030714 |
Pharmacological modulation of perceptual learning and associated cortical reorganization. | Science (New York, N.Y.) 20030704 |
Distinct effects of amantadine and memantine on dopaminergic transmission in the rat striatum. | Neuroscience letters 20030612 |
[Early treatment with anti-dementia drugs when possible. These signs reveal Alzheimer disease]. | MMW Fortschritte der Medizin 20030605 |
A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis. | Journal of magnetic resonance imaging : JMRI 20030601 |
[Memantine]. | Neurologia (Barcelona, Spain) 20030601 |
Efficacy of the NMDA-receptor antagonist memantine in patients with chronic phantom limb pain--results of a randomized double-blinded, placebo-controlled trial. | Pain 20030601 |
[Memantine brakes Alzheimer's dementia. The NMDA antagonist is effective in severe cases, too]. | MMW Fortschritte der Medizin 20030526 |
[Current therapy of patients with dementia]. | MMW Fortschritte der Medizin 20030526 |
[Anti-dementia therapy pays at every stage of the disease. Patients with Alzheimer's disease stay all-day fit longer]. | MMW Fortschritte der Medizin 20030526 |
NMDA receptor activity and the transmission of sensory input into motor output in introverts and extraverts. | The Quarterly journal of experimental psychology. B, Comparative and physiological psychology 20030501 |
Effects of memantine, an NMDA receptor antagonist, on place preference conditioned with drug and nondrug reinforcers in mice. | Behavioural pharmacology 20030501 |
Cortical reorganisation and chronic pain: implications for rehabilitation. | Journal of rehabilitation medicine 20030501 |
[The effects of milkvetch and memantain on the synthesis of cerebral PAF in neonatal rats with hypoxic-ischemic reperfusion]. | Zhonghua er ke za zhi = Chinese journal of pediatrics 20030501 |
Development of a liquid chromatography-mass spectrometric method for measuring the binding of memantine to different melanins. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030425 |
Are neuronal nicotinic receptors a target for antiepileptic drug development? Studies in different seizure models in mice and rats. | European journal of pharmacology 20030411 |
Memantine in moderate-to-severe Alzheimer's disease. | The New England journal of medicine 20030403 |
Comments on the NMDA antagonist memantine. | Methods and findings in experimental and clinical pharmacology 20030401 |
Possible role for memantine in protecting retinal ganglion cells from glaucomatous damage. | Survey of ophthalmology 20030401 |
The regulatory effect of memantine on expression and synthesis of heat shock protein 70 gene in neonatal rat models with cerebral hypoxic ischemia. | Chinese medical journal 20030401 |
Tolerability of memantine in combination with cholinesterase inhibitors in dementia therapy. | International clinical psychopharmacology 20030301 |
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety. | Neuroscience and behavioral physiology 20030301 |
The ability of new non-competitive glutamate receptor blockers to weaken motor disorders in animals. | Neuroscience and behavioral physiology 20030301 |
[Prevention of dementias: state of the art]. | Deutsche medizinische Wochenschrift (1946) 20030227 |
Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats. | Psychopharmacology 20030201 |
Alzheimer's disease: emerging noncholinergic treatments. | Geriatrics 20030201 |
[Treatment with NMDA antagonist controls neuron death. Even in severe dementia it is not too late]. | MMW Fortschritte der Medizin 20030116 |
Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice. | Psychopharmacology 20030101 |
Memantine for dementia. | The Cochrane database of systematic reviews 20030101 |
[The challenge of Alzheimer dementia]. | Pharmazie in unserer Zeit 20030101 |
Antinociceptive effect in mice of intraperitoneal N-methyl-D-aspartate receptor antagonists in the formalin test. | European journal of pain (London, England) 20030101 |
Resource utilisation and cost analysis of memantine in patients with moderate to severe Alzheimer's disease. | PharmacoEconomics 20030101 |
Molecule of the month. Memantine hydrochloride. | Drug news & perspectives 20030101 |
Memantine. | Drugs & aging 20030101 |
Comparison of the effect of NT-0409 and antidementia drugs on learning and memory in rats with chronic cerebral cholinergic deficiency. | Bulletin of experimental biology and medicine 20030101 |
The glutamatergic system and Alzheimer's disease: therapeutic implications. | CNS drugs 20030101 |
A placebo-controlled study of memantine (Ebixa) in dementia of Wernicke-Korsakoff syndrome. | Medicinski arhiv 20030101 |
Memantine for dementia. | The Cochrane database of systematic reviews 20030101 |
Antagonists and agonists at the glycine site of the NMDA receptor for therapeutic interventions. | European journal of medicinal chemistry 20030101 |
The search for better noncholinergic treatment options for Alzheimer's disease. | The Journal of clinical psychiatry 20030101 |
Current treatment for Alzheimer disease and future prospects. | Alzheimer disease and associated disorders 20030101 |
The neuropharmacological basis for the use of memantine in the treatment of Alzheimer's disease. | CNS drug reviews 20030101 |
Alzheimer's disease and the glutamate NMDA receptor. | Psychopharmacology bulletin 20030101 |
[Mechanisms of action of Alzheimer medications]. | Duodecim; laaketieteellinen aikakauskirja 20030101 |
FDA approves memantine drug for treating AD. | American journal of Alzheimer's disease and other dementias 20030101 |
Sigma1 receptor antagonists attenuate antidepressant-like effect induced by co-administration of 1,3 di-o-tolylguanidine (DTG) and memantine in the forced swimming test in rats. | Polish journal of pharmacology 20030101 |
Memantine in vascular dementia. | International psychogeriatrics 20030101 |
Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40). | Brain research 20021220 |
[Early diagnosis and treatment of Alzheimer's disease. Implementation in the doctor's office]. | Fortschritte der Medizin. Originalien 20021205 |
Involvement of nitric oxide in myotoxicity produced by diisopropylphosphorofluoridate (DFP)-induced muscle hyperactivity. | Archives of toxicology 20021201 |
Effects of the NMDA antagonist memantine on human methamphetamine discrimination. | Psychopharmacology 20021201 |
Neuroprotective effect of memantine in different retinal injury models in rats. | Journal of glaucoma 20021201 |
Memantine offers new possibilities for the treatment of VaD. | The Lancet. Neurology 20021201 |
A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500). | International clinical psychopharmacology 20021101 |
[Anti-dementia drugs for Alzheimer disease in present and future]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101 |
Chronic multichannel recordings from organotypic hippocampal slice cultures: protection from excitotoxic effects of NMDA by non-competitive NMDA antagonists. | Journal of neuroscience methods 20021030 |
NMDA receptor antagonists to characterize rat renal organic cation transporter function. | European journal of pharmacology 20020927 |
Effects of anti-glaucoma medications on ganglion cell survival: the DBA/2J mouse model. | Vision research 20020901 |
New therapies. New Alzheimer's treatments that may ease the mind. | Science (New York, N.Y.) 20020823 |
Modulation of formalin-induced behaviors and edema by local and systemic administration of dextromethorphan, memantine and ketamine. | European journal of pharmacology 20020823 |
[Case report. Dementia with apathy]. | MMW Fortschritte der Medizin 20020808 |
Modulation of blood-brain barrier dysfunction and neurological deficits during acute experimental allergic encephalomyelitis by the N-methyl-D-aspartate receptor antagonist memantine. | The Journal of pharmacology and experimental therapeutics 20020701 |
Efficacy and safety of memantine in patients with mild to moderate vascular dementia: a randomized, placebo-controlled trial (MMM 300). | Stroke 20020701 |
[Use of memantine in progressive glaucoma. Case report]. | Klinische Monatsblatter fur Augenheilkunde 20020701 |
Treatment of spasticity. | Spinal cord 20020601 |
Trends in neuroprotection. | Archivos de la Sociedad Espanola de Oftalmologia 20020601 |
Phenytoin blocks retinal ganglion cell death after partial optic nerve crush. | Experimental eye research 20020601 |
Neuroprotective effect of memantine in a rabbit model of optic nerve ischemia. | Korean journal of ophthalmology : KJO 20020601 |
Ketamine, an N-methyl-D-aspartate receptor antagonist, inhibits the reflex responses to distension of the rat urinary bladder. | Anesthesiology 20020601 |
Ketamine, an N-methyl-D-aspartate receptor antagonist, inhibits the spinal neuronal responses to distension of the rat urinary bladder. | Anesthesiology 20020601 |
Dextromethorphan and memantine in painful diabetic neuropathy and postherpetic neuralgia: efficacy and dose-response trials. | Anesthesiology 20020501 |
Memantine. Merz. | Current opinion in investigational drugs (London, England : 2000) 20020501 |
Quantitative analysis of memantine in human plasma by gas chromatography/negative ion chemical ionization/mass spectrometry. | Journal of mass spectrometry : JMS 20020501 |
Memantine does not block antiaggressive effects of morphine in mice. | Behavioural pharmacology 20020501 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Channel blockers acting at N-methyl-D-aspartate receptors: differential effects of mutations in the vestibule and ion channel pore. | Molecular pharmacology 20020301 |
[Geriatric assessment in 3 steps. Often mental decline is not correctly assessed]. | MMW Fortschritte der Medizin 20020221 |
PET studies of 18F-memantine in healthy volunteers. | Nuclear medicine and biology 20020201 |
Electrophoretic behavior of adamantane derivatives possessing antiviral activity and their determination by capillary zone electrophoresis with indirect detection. | Electrophoresis 20020101 |
Different action of memantine and caroverine on glutamatergic transmission in the mammalian cochlea. | Advances in oto-rhino-laryngology 20020101 |
New approaches to clinical trials in vascular dementia: memantine in small vessel disease. | Cerebrovascular diseases (Basel, Switzerland) 20020101 |
[The agony and (rational) alternative. Recommendations of the drug commission on antidementia agents]. | Pharmazie in unserer Zeit 20020101 |
The leading role of mitochondrial depolarization in the mechanism of glutamate-induced disruptions in Ca2+ homeostasis. | Neuroscience and behavioral physiology 20020101 |
Non-cholinergic strategies for treating and preventing Alzheimer's disease. | CNS drugs 20020101 |
Glutamate receptors as a target for Alzheimer's disease--are clinical results supporting the hope? | Journal of neural transmission. Supplementum 20020101 |
Defining the role of the caregiver in Alzheimer's disease treatment. | Drugs & aging 20020101 |
[Prospects for neuroprotective glaucoma therapy]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20011001 |
Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126. | Journal of neuroscience research 20010915 |
Glutamate release promotes growth of malignant gliomas. | Nature medicine 20010901 |
The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain. | Molecular and cellular neurosciences 20010901 |
Excitotoxicity can be mediated through an interaction within the optic nerve; activation of cell body NMDA receptors is not required. | Veterinary ophthalmology 20010901 |
Neuroprotection by memantine, a non-competitive NMDA receptor antagonist after traumatic brain injury in rats. | Brain research 20010817 |
Memantine, but not dizocilpine, ameliorates cognitive deficits in adult rats withdrawn from chronic ingestion of alcohol. | Neuroscience letters 20010817 |
The NMDA antagonist memantine attenuates the expression of opioid physical dependence in humans. | Psychopharmacology 20010801 |
Memantine inhibits efferent cholinergic transmission in the cochlea by blocking nicotinic acetylcholine receptors of outer hair cells. | Molecular pharmacology 20010701 |
The in vivo relevance of the varied channel-blocking properties of uncompetitive NMDA antagonists: tests on spinal neurones. | Neuropharmacology 20010701 |
The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner. | Neuroscience letters 20010622 |
Private investigations. | Nature 20010510 |
[Drug therapy of dementia. Improving cognitive performance]. | MMW Fortschritte der Medizin 20010503 |
Comparison of the effects of ketamine and memantine on prolactin and cortisol release in men. a randomized, double-blind, placebo-controlled trial. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010501 |
The N-methyl-D-aspartate antagonist memantine has no neuroprotective effect during hypothermic circulatory arrest: a study in the chronic porcine model. | The Journal of thoracic and cardiovascular surgery 20010501 |
The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801. | Neuropharmacology 20010501 |
Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey. | Survey of ophthalmology 20010501 |
Eliciting paresthesias for peripheral nerve block: a harmful clinical standard? | Anesthesia and analgesia 20010301 |
Comparison of the effects of MK-801, ketamine and memantine on responses of spinal dorsal horn neurones in a rat model of mononeuropathy. | Pain 20010301 |
[Neuroprotection. Bases and possibilities of a future clinical use]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20010301 |
Drugs for treatment of Alzheimer's disease. | International journal of clinical practice 20010301 |
Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat. | European journal of pharmacology 20010209 |
Uncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptors alter the mRNA expression of proteins associated with the NMDA receptor complex. | Pharmacology & toxicology 20010201 |
Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil. | Neuropharmacology 20010101 |
Effect of drugs used for neuropathic pain management on tetrodotoxin-resistant Na(+) currents in rat sensory neurons. | Anesthesiology 20010101 |
Memantine treatment in alcohol dementia: rapid PET changes and clinical course. | European neurology 20010101 |
Effects of pharmacologically induced changes in NMDA-receptor activity on long-term memory in humans. | Learning & memory (Cold Spring Harbor, N.Y.) 20010101 |
Co-administration of memantine and amantadine with sub/suprathreshold doses of L-Dopa restores motor behaviour of MPTP-treated mice. | Journal of neural transmission (Vienna, Austria : 1996) 20010101 |
The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats. | Bulletin of experimental biology and medicine 20010101 |
[Current strategies of pathogenetic therapy of Alzheimer's disease]. | Vestnik Rossiiskoi akademii meditsinskikh nauk 20010101 |
If only we can stop the progression... | American journal of Alzheimer's disease and other dementias 20010101 |
NMDA antagonists inhibit the development of ethanol dependence in rats. | Polish journal of pharmacology 20010101 |
Effects of the NMDA receptor channel blockers memantine and MRZ 2/579 on morphine withdrawal-facilitated aggression in mice. | Psychopharmacology 20000501 |
Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: protection by memantine. | Annals of neurology 20000201 |
Prevention of cocaine-induced convulsions and lethality in mice: effectiveness of targeting different sites on the NMDA receptor complex. | Neuropharmacology 20000128 |
[A comparative study of the central H-cholinergic-blocking and NMDA-blocking actions of MK-801, memantin, amantadine, pyrilen and IEM-1754 in experiments on intact rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20000101 |
Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents--toward an understanding of their favorable tolerability. | Amino acids 20000101 |
Anticonvulsant efficacy of N-methyl-D-aspartate antagonists against convulsions induced by cocaine. | The Journal of pharmacology and experimental therapeutics 19990501 |
The glutamatergic system and neurodegeneration in dementia: preventive strategies in Alzheimer's disease. | International journal of geriatric psychiatry 19990101 |
Anticonvulsants for soman-induced seizure activity. | Journal of biomedical science 19990101 |
How to overcome resistance of influenza A viruses against adamantane derivatives. | Antiviral research 19980201 |
Inhibition by memantine of the development of persistent oral dyskinesias induced by long-term haloperidol treatment of rats. | British journal of pharmacology 19961001 |
Are NMDA antagonistic properties relevant for antiparkinsonian-like activity in rats?--case of amantadine and memantine. | Journal of neural transmission. Parkinson's disease and dementia section 19940101 |
gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine. | European journal of pharmacology 19920701 |
Pharmacotoxic psychosis after memantine in Parkinson's disease. | Lancet (London, England) 19911019 |
Susceptibility of primary human glial fibrillary acidic protein-positive brain cells to human immunodeficiency virus infection in vitro: anti-HIV activity of memantine. | AIDS research and human retroviruses 19910101 |
Methyl parathion acute toxicity: prophylaxis and therapy with memantine and atropine. | Archives internationales de pharmacodynamie et de therapie 19900101 |
[Memantine and neurogenic bladder disorders within the bounds of spastic conditions]. | Arzneimittel-Forschung 19820101 |