Home Sulfos 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-Dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

CAS No.:
199666-03-0
Catalog Number:
AG002C9V
Molecular Formula:
C17H15N3O6S2
Molecular Weight:
421.4475
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$140
- +
10mg
99%
1 week
United States
$168
- +
25mg
≥98%
1 week
United States
$350
- +
50mg
99%
1 week
United States
$362
- +
100mg
99%
1 week
United States
$543
- +
200mg
99%
1 week
United States
$960
- +
Product Description
Catalog Number:
AG002C9V
Chemical Name:
3,4-Dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
CAS Number:
199666-03-0
Molecular Formula:
C17H15N3O6S2
Molecular Weight:
421.4475
MDL Number:
MFCD11040807
IUPAC Name:
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
InChI:
InChI=1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
InChI Key:
NDPBMCKQJOZAQX-UHFFFAOYSA-N
SMILES:
COc1cc(ccc1OC)S(=O)(=O)Nc1scc(n1)c1cccc(c1)[N+](=O)[O-]
Properties
Complexity:
638  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
421.04g/mol
Formal Charge:
0
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
421.442g/mol
Monoisotopic Mass:
421.04g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
160A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.2  
Literature
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Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell 20110610
Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis. Journal of neuropathology and experimental neurology 20101101
Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides. Neuropharmacology 20100101
Implication of NMDA receptors in the antidyskinetic activity of cabergoline, CI-1041, and Ro 61-8048 in MPTP monkeys with levodopa-induced dyskinesias. Journal of molecular neuroscience : MN 20090601
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. Brain : a journal of neurology 20090501
Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria. International journal for parasitology 20090201
Kynurenine pathway metabolites in humans: disease and healthy States. International journal of tryptophan research : IJTR 20090101
Effects of the kynurenine 3-hydroxylase inhibitor Ro 61-8048 after intrastriatal injections on the severity of dystonia in the dt sz mutant. European journal of pharmacology 20080531
Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys. Behavioural brain research 20080125
Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys. Movement disorders : official journal of the Movement Disorder Society 20050701
Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus. Neuropharmacology 20050501
The kynurenine 3-hydroxylase inhibitor Ro 61-8048 improves dystonia in a genetic model of paroxysmal dyskinesia. European journal of pharmacology 20030930
Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures. Journal of neurochemistry 20020901
Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis. Neuroscience 20010101
Properties