Home Halogens 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-

CAS No.:
19794-93-5
Catalog Number:
AG002B6W
Molecular Formula:
C19H22ClN5O
Molecular Weight:
371.8639
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
In Stock USA
United States
$473
- +
1g
In Stock USA
United States
$1036
- +
Product Description
Catalog Number:
AG002B6W
Chemical Name:
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-
CAS Number:
19794-93-5
Molecular Formula:
C19H22ClN5O
Molecular Weight:
371.8639
MDL Number:
MFCD00242886
IUPAC Name:
2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
InChI:
InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2
InChI Key:
PHLBKPHSAVXXEF-UHFFFAOYSA-N
SMILES:
Clc1cccc(c1)N1CCN(CC1)CCCn1nc2n(c1=O)cccc2
EC Number:
243-317-1
UNII:
YBK48BXK30
Properties
Complexity:
611  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
371.151g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
371.869g/mol
Monoisotopic Mass:
371.151g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
42.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.8  
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Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors. Bioorganic & medicinal chemistry letters 20091201
Metabolite identification in rat brain microdialysates by direct infusion nanoelectrospray ionization after desalting on a ZipTip and LTQ/Orbitrap mass spectrometry. Rapid communications in mass spectrometry : RCM 20091201
The clinical use of drugs influencing neurotransmitters in the brain to promote motor recovery after stroke; a Cochrane systematic review. European journal of physical and rehabilitation medicine 20091201
Diagnosis and treatment of erectile dysfunction--a practical update. Journal of medicine and life 20091115
Determination of antidepressants in human postmortem blood, brain tissue, and hair using gas chromatography-mass spectrometry. International journal of legal medicine 20091101
Packages of care for dementia in low- and middle-income countries. PLoS medicine 20091101
Applications of high content screening in life science research. Combinatorial chemistry & high throughput screening 20091101
Non-traumatic urologic emergencies in men: a clinical review. The western journal of emergency medicine 20091101
Persistent genital arousal disorder and trazodone. Morphometric and vascular modifications of the clitoris. A case report. The journal of sexual medicine 20091001
Accuracy of Veterans Affairs databases for diagnoses of chronic diseases. Preventing chronic disease 20091001
Fulminant hepatic failure induced by venlafaxine and trazodone therapy: a case report. Transplantation proceedings 20091001
Mechanism of action of trazodone: a multifunctional drug. CNS spectrums 20091001
Expert opinion on the management of behavioural and psychological symptoms of dementia (BPSD) and investigation into prescribing practices in the UK. International journal of geriatric psychiatry 20090901
Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity. Toxicology in vitro : an international journal published in association with BIBRA 20090901
General unknown screening procedure for the characterization of human drug metabolites in forensic toxicology: applications and constraints. Journal of separation science 20090901
Treatment of sleep dysfunction and psychiatric disorders. Current treatment options in neurology 20090901
The impact of neuroimmune dysregulation on neuroprotection and neurotoxicity in psychiatric disorders--relation to drug treatment. Dialogues in clinical neuroscience 20090901
Intoxication with trazodone caused by dirty facsimile machine. Journal of the American Geriatrics Society 20090901
Carbamazepine-induced hyperammonemia. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090815
A sleepy patient with REM rebound. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090815
Comparative study on the gastroprotective potential of some antidepressants in indomethacin-induced ulcer in rats. Chemico-biological interactions 20090715
Electro-oxidation and determination of trazodone at multi-walled carbon nanotube-modified glassy carbon electrode. Talanta 20090715
Application of a trazodone-selective electrode to pharmaceutical quality control and urine analyses. Analytical and bioanalytical chemistry 20090701
Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers. Journal of psychopharmacology (Oxford, England) 20090701
Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption. Journal of psychopharmacology (Oxford, England) 20090701
Short-term clarithromycin administration impairs clearance and enhances pharmacodynamic effects of trazodone but not of zolpidem. Clinical pharmacology and therapeutics 20090601
[Clinically relevant drug interactions with new generation antidepressants and antipsychotics]. Therapeutische Umschau. Revue therapeutique 20090601
The use of an antagonist 5-HT2a/c for depression and motor function in Parkinson' disease. Arquivos de neuro-psiquiatria 20090601
[Trazodone: a new selective approach to the treatment of hot flashes induced by androgen deprivation in prostate carcinoma?]. Actas urologicas espanolas 20090601
5-Hydroxytryptamine Receptor Subtypes and their Modulators with Therapeutic Potentials. Journal of clinical medicine research 20090601
Determination of articaine in human plasma by liquid chromatography-mass spectrometry and its application in a preliminary pharmacokinetic study. Journal of pharmaceutical and biomedical analysis 20090501
Antidepressant switching among adherent patients treated for depression. Psychiatric services (Washington, D.C.) 20090501
[Frontotemporal dementia: neurotransmitter and clinical symptoms with focus on therapeutic targets]. Fortschritte der Neurologie-Psychiatrie 20090501
Borderline personality disorder: inpatient psychiatric nursing management. Journal of psychosocial nursing and mental health services 20090501
Extended-release Trazodone in Major Depressive Disorder: A Randomized, Double-blind, Placebo-controlled Study. Psychiatry (Edgmont (Pa. : Township)) 20090501
Incidence of major malformations in infants following antidepressant exposure in pregnancy: results of a large prospective cohort study. Canadian journal of psychiatry. Revue canadienne de psychiatrie 20090401
Combined cardiac sympathetic excitation and vagal impairment in patients with non-organic erectile dysfunction. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20090201
Trazodone hypnotic effect and nocturnal melatonin secretion. Journal of clinical psychopharmacology 20090201
Non-fatal overdose of duloxetine in combination with other antidepressants and benzodiazepines. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101
Hypnotic use for insomnia management in chronic obstructive pulmonary disease. Sleep medicine 20090101
Trazodone for the treatment of sexual dysfunction induced by serotonin reuptake inhibitors: a preliminary open-label study. Clinical neuropharmacology 20090101
Psychiatric treatment of patients predisposed to priapism induced by quetapine, trazadone and risperidone: a case report. General hospital psychiatry 20090101
Transient loss of consciousness caused by cryptococcal meningitis in an immunocompetent patient: a case report. Cases journal 20090101
An analysis of correlations among four outcome scales employed in clinical trials of patients with major depressive disorder. Annals of general psychiatry 20090101
Clinical features and diagnosis of frontotemporal dementia. Frontiers of neurology and neuroscience 20090101
Frontotemporal dementia: therapeutic interventions. Frontiers of neurology and neuroscience 20090101
The Pediatric Obsessive-Compulsive Disorder Treatment Study II: rationale, design and methods. Child and adolescent psychiatry and mental health 20090101
Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature. Nutrition & metabolism 20090101
Insomnia in patients with depression: some pathophysiological and treatment considerations. CNS drugs 20090101
Trazodone generates m-CPP: in 2008 risks from m-CPP might outweigh benefits of trazodone. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101
Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine. BMC emergency medicine 20090101
Role of atazanavir in the treatment of HIV infection. Therapeutics and clinical risk management 20090101
Persistence and compliance to antidepressant treatment in patients with depression: a chart review. BMC psychiatry 20090101
Psychopharmacology of ADHD in pediatrics: current advances and issues. Neuropsychiatric disease and treatment 20090101
Adjustment Disorder: epidemiology, diagnosis and treatment. Clinical practice and epidemiology in mental health : CP & EMH 20090101
The sedating antidepressant trazodone impairs sleep-dependent cortical plasticity. PloS one 20090101
Test-retest variability of high resolution positron emission tomography (PET) imaging of cortical serotonin (5HT2A) receptors in older, healthy adults. BMC medical imaging 20090101
Olanzapine and fluoxetine combination therapy for treatment-resistant depression: review of efficacy, safety, and study design issues. Neuropsychiatric disease and treatment 20090101
Managing agitation associated with traumatic brain injury: behavioral versus pharmacologic interventions? PM & R : the journal of injury, function, and rehabilitation 20090101
Managing treatment-experienced pediatric and adolescent HIV patients: role of darunavir. Therapeutics and clinical risk management 20090101
Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs 20090101
More questions than answers! Clinical dilemmas in psychopharmacology in pregnancy and lactation. Indian journal of psychiatry 20090101
Serotonin syndrome associated with sertraline, trazodone and tramadol abuse. Indian journal of psychiatry 20090101
ECG for the diagnosis of pulmonary embolism when conventional imaging cannot be utilized: a case report and review of the literature. Indian pacing and electrophysiology journal 20090101
Drugs associated with more suicidal ideations are also associated with more suicide attempts. PloS one 20090101
Possible role of trazodone and imipramine in sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. Methods and findings in experimental and clinical pharmacology 20090101
Electroencephalographic correlates of Chronic Fatigue Syndrome. Behavioral and brain functions : BBF 20090101
Medication management and practices in prison for people with mental health problems: a qualitative study. International journal of mental health systems 20090101
Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles. Arthritis research & therapy 20090101
Algorithms for the assessment and management of insomnia in primary care. Patient preference and adherence 20090101
Evidence for anomalous network connectivity during working memory encoding in schizophrenia: an ICA based analysis. PloS one 20090101
Pharmacological and combined interventions for the acute depressive episode: focus on efficacy and tolerability. Therapeutics and clinical risk management 20090101
Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults. Neuropsychiatric disease and treatment 20090101
Depression with panic episodes and coronary vasospasm. Cardiovascular psychiatry and neurology 20090101
Enhanced Interaction between Warfarin and High-Dose Ketoconazole: A Case Report. Case reports in medicine 20090101
Social phobia following maprotiline: the first case report. Cases journal 20090101
Depression following thrombotic cardiovascular events in elderly medicare beneficiaries: risk of morbidity and mortality. Cardiology research and practice 20090101
Gastroesophageal reflux disease: medical or surgical treatment? Gastroenterology research and practice 20090101
New sensitive kinetic spectrophotometric methods for determination of omeprazole in dosage forms. International journal of analytical chemistry 20090101
Spectroscopic and electrochemical analysis of psychotropic drugs. Indian journal of pharmaceutical sciences 20090101
Intractable depression successfully treated with a combination of autogenic training and high-dose antidepressant in department of otorhinolaryngology: a case report. Cases journal 20090101
The efficacy and tolerability of once-daily controlled-release trazodone for depressed mood, anxiety, insomnia, and suicidality in major depressive disorder. Psychopharmacology bulletin 20090101
Frontotemporal dementia: An updated overview. Indian journal of psychiatry 20090101
Behavioral and psychological symptoms of dementia and their management. Indian journal of psychiatry 20090101
Use of trazodone as an adjunctive agent in the treatment of canine anxiety disorders: 56 cases (1995-2007). Journal of the American Veterinary Medical Association 20081215
[Peritoneal dialysis patient affected with serotonin syndrome]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20081210
Prioritizing future research on off-label prescribing: results of a quantitative evaluation. Pharmacotherapy 20081201
Nocturia: a blinded, randomized, parallel placebo-controlled self-study of the effect of 5 different sedatives and analgesics. Canadian Urological Association journal = Journal de l'Association des urologues du Canada 20081201
Trazodone improves the results of cognitive behaviour therapy of primary insomnia in non-depressed patients. Neuro endocrinology letters 20081201
Toward achieving optimal response: understanding and managing antidepressant side effects. Dialogues in clinical neuroscience 20081201
Sleep disturbances and depression: risk relationships for subsequent depression and therapeutic implications. Dialogues in clinical neuroscience 20081201
Triple reuptake inhibitors: the next generation of antidepressants. Current neuropharmacology 20081201
Pharmacology and therapeutic potential of sigma(1) receptor ligands. Current neuropharmacology 20081201
Using second-generation antidepressants to treat depressive disorders: a clinical practice guideline from the American College of Physicians. Annals of internal medicine 20081118
Comparative benefits and harms of second-generation antidepressants: background paper for the American College of Physicians. Annals of internal medicine 20081118
[Restless legs syndrome, periodic limb movements, and psychopharmacology]. Der Nervenarzt 20081101
Clitoral priapism with no known risk factors. The western journal of emergency medicine 20081101
A fatal case due to combined toxicity of psychotropic drugs. Forensic science international 20081025
Osteoporosis after combined use of a neuroleptic and antidepressants. Pharmacy world & science : PWS 20081001
Meta-analysis of major depressive disorder relapse and recurrence with second-generation antidepressants. Psychiatric services (Washington, D.C.) 20081001
Dose-dependent response of central dopaminergic systems to buspirone in mice. Indian journal of experimental biology 20081001
Trazodone for sleep disturbance after alcohol detoxification: a double-blind, placebo-controlled trial. Alcoholism, clinical and experimental research 20080901
Sleep disorders as core symptoms of depression. Dialogues in clinical neuroscience 20080901
Triple reuptake inhibitors: a premise and promise. Psychiatry investigation 20080901
Quetiapine versus trazodone in reducing rehospitalization for alcohol dependence: a large data-base study. Journal of addiction medicine 20080901
HPLC analysis of the antidepressant trazodone and its main metabolite m-CPP in human plasma. Journal of pharmaceutical and biomedical analysis 20080805
Management of ventricular dysrhythmia secondary to trazodone overdose. The Journal of emergency medicine 20080801
Tardive dystonia and tardive sensory syndrome related to trazodone: a case report. Progress in neuro-psychopharmacology & biological psychiatry 20080801
High throughput and sensitive determination of trazodone and its primary metabolite, m-chlorophenylpiperazine, in human plasma by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080801
Critical evaluation of buffering solutions for pKa determination by capillary electrophoresis. Electrophoresis 20080701
Trazodone increases arousal threshold in obstructive sleep apnoea. The European respiratory journal 20080601
Combined use of carbon nanotubes and ionic liquid to improve the determination of antidepressants in urine samples by liquid chromatography. Analytical and bioanalytical chemistry 20080601
In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone. Toxicological sciences : an official journal of the Society of Toxicology 20080601
Topiramate in the prevention of pediatric migraine: literature review. The journal of headache and pain 20080601
Acute chlorophenylpiperazine overdose: a case report and review of the literature. Therapeutic drug monitoring 20080601
Treatment of fragile X-associated tremor ataxia syndrome (FXTAS) and related neurological problems. Clinical interventions in aging 20080601
Promising avenues of therapeutics for bipolar illness. Dialogues in clinical neuroscience 20080601
Disruption of bradycardia associated with discriminative conditioning in combat veterans with PTSD. Neuropsychiatric disease and treatment 20080601
Three cases of reversible agranulocytosis after treatment with lamotrigine. Psychiatry investigation 20080601
The association between antidepressant use and disturbances in glucose homeostasis: evidence from spontaneous reports. European journal of clinical pharmacology 20080501
Detection of novel reactive metabolites of trazodone: evidence for CYP2D6-mediated bioactivation of m-chlorophenylpiperazine. Drug metabolism and disposition: the biological fate of chemicals 20080501
Antidepressant drugs and memory: insights from animal studies. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080401
Augmentation of antidepressants with atypical antipsychotics for treatment-resistant major depressive disorder. Acta psychiatrica Scandinavica 20080401
[Sexual dysfunctions induced by antidepressants and antipsychotics]. Revue medicale suisse 20080326
Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction. Molecular pharmacology 20080301
The effectiveness of anticonvulsants in psychiatric disorders. Dialogues in clinical neuroscience 20080301
Pharmacotherapy for insomnia. Clinics in geriatric medicine 20080201
Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. PLoS medicine 20080201
Epidemiology and treatment of post-stroke depression. Neuropsychiatric disease and treatment 20080201
A review of ramelteon in the treatment of sleep disorders. Neuropsychiatric disease and treatment 20080201
Pharmacological management of panic disorder. Neuropsychiatric disease and treatment 20080201
Rasagiline in treatment of Parkinson's disease. Neuropsychiatric disease and treatment 20080201
Trazodone for Alzheimer's disease: a naturalistic follow-up study. Archives of gerontology and geriatrics 20080101
Priapism associated with atypical antipsychotic medications: a review. International clinical psychopharmacology 20080101
Improving sedative-hypnotic prescribing in older hospitalized patients: provider-perceived benefits and barriers of a computer-based reminder. Journal of general internal medicine 20080101
QT Prolongation and delayed atrioventricular conduction caused by acute ingestion of trazodone. Clinical toxicology (Philadelphia, Pa.) 20080101
Prevalence of contraindications to mefloquine use among USA military personnel deployed to Afghanistan. Malaria journal 20080101
Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress. BMC complementary and alternative medicine 20080101
Pharmacological management of neuropathic pain following spinal cord injury. CNS drugs 20080101
Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report. Journal of medical case reports 20080101
Priapism, ecstasy, and marijuana: is there a connection? Advances in urology 20080101
Chronic hypokalemia due to excessive cola consumption: a case report. Cases journal 20080101
Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy? Depression and anxiety 20080101
Idiopathic low-flow priapism in prepuberty: a case report and a review of literature. Advances in urology 20080101
Imaging the neural circuitry and chemical control of aggressive motivation. BMC neuroscience 20080101
Antidepressants for the treatment of insomnia : a suitable approach? Drugs 20080101
Ex vivo and in vivo evaluation of transdermal formulation of trazodone hydrochloride. Acta poloniae pharmaceutica 20080101
Nitric oxide modulation mediates the protective effect of trazodone in a mouse model of chronic fatigue syndrome. Pharmacological reports : PR 20080101
Evaluation and management of patients with noncardiac chest pain. Gastroenterology research and practice 20080101
Utility of 7,7,8,8-tetracyanoquinodimethane charge transfer reagent for the spectrophotometric determination of trazodone, amineptine and amitriptyline hydrochlorides. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071231
Comparison of electron and chemical ionization modes by validation of a quantitative gas chromatographic-mass spectrometric assay of new generation antidepressants and their active metabolites in plasma. Journal of chromatography. A 20071228
[Pharmacological treatment options in frontotemporal dementia]. Fortschritte der Neurologie-Psychiatrie 20071201
How useful are prescribing indicators based on the DU90% method to distinguish the quality of prescribing between pharmacotherapy audit meetings with different levels of functioning? European journal of clinical pharmacology 20071201
Pharmacokinetics and elimination of quetiapine, venlafaxine, and trazodone during pregnancy and postpartum. Journal of clinical psychopharmacology 20071201
Rivastigmine-induced dystonia. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20071201
Addition of trazodone to sertraline: a probable synergistic action in a case of obsessive-compulsive disorder. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20071201
Management of the behavioral and psychological symptoms of dementia. Clinical interventions in aging 20071201
Pharmacologic treatments for opioid dependence: detoxification and maintenance options. Dialogues in clinical neuroscience 20071201
Hepatitis C for addiction professionals. Addiction science & clinical practice 20071201
[Frontotemporal dementia: a review]. L'Encephale 20071201
Pharmacogenetics of antipsychotic adverse effects: Case studies and a literature review for clinicians. Neuropsychiatric disease and treatment 20071201
Extremely prolonged INR associated with warfarin in combination with both trazodone and omega-3 fatty acids. Archives of medical research 20071101
Discriminative stimulus properties of the selective norepinephrine reuptake inhibitor, reboxetine, in rats: a characterization with alpha/beta-adrenoceptor subtype selective ligands, antidepressants, and antagonists at neuropeptide receptors. The international journal of neuropsychopharmacology 20071001
A meta-analysis of clinical trials comparing the serotonin (5HT)-2 receptor antagonists trazodone and nefazodone with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. European psychiatry : the journal of the Association of European Psychiatrists 20071001
[Frontotemporal dementia]. Presse medicale (Paris, France : 1983) 20071001
Sedation of children with ADHD: trazodone or midazolam? Paediatric anaesthesia 20071001
Pharmacologic management of neuropsychiatric symptoms of Alzheimer disease. Canadian journal of psychiatry. Revue canadienne de psychiatrie 20071001
Pharmacological causes of hyperprolactinemia. Therapeutics and clinical risk management 20071001
Family history, early adversity and the hypothalamic-pituitary-adrenal (HPA) axis: Mediation of the vulnerability to mood disorders. Neuropsychiatric disease and treatment 20071001
Risk assessment for defibrillator therapy: Il Trittico. Journal of the American College of Cardiology 20070918
Prevalence and predictors of antidepressant use in a cohort of pregnant women. BJOG : an international journal of obstetrics and gynaecology 20070901
[Review of pharmacological efficacies and side effects of antidepressants]. Nihon rinsho. Japanese journal of clinical medicine 20070901
Neuroleptic malignant syndrome resulting from a complex drug-drug interaction: 'I don't see 'em!'. Journal of psychiatric practice 20070901
Eszopiclone for late-life insomnia. Clinical interventions in aging 20070901
Effect of various classes of antidepressants in behavioral paradigms of despair. Progress in neuro-psychopharmacology & biological psychiatry 20070815
Proof of a 1-(3-chlorophenyl)piperazine (mCPP) intake: use as adulterant of cocaine resulting in drug-drug interactions? Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070815
Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride. European journal of pharmacology 20070813
Trazodone inhibits T-type calcium channels. Neuropharmacology 20070801
Serotonin syndrome in elderly patients treated for psychotic depression with atypical antipsychotics and antidepressants: two case reports. CNS spectrums 20070801
N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed. Current drug metabolism 20070801
Comparison of trazodone, diazepame and dibenzepine influences on rat brain beta-endorphins content. Bosnian journal of basic medical sciences 20070801
Prolonged QT associated with an overdose of trazodone. The Journal of clinical psychiatry 20070801
Evaluation of patient care interventions and recommendations by a transitional care pharmacist. Therapeutics and clinical risk management 20070801
Agomelatine and its therapeutic potential in the depressed patient. Neuropsychiatric disease and treatment 20070801
Determination of trazodone in urine and pharmaceuticals using micellar liquid chromatography with fluorescence detection. Journal of chromatography. A 20070713
Reasons for antidepressant prescriptions in Canada. Pharmacoepidemiology and drug safety 20070701
A rational combination pharmacotherapy in men with erectile dysfunction who initially failed to oral sildenafil citrate alone: a pilot study. The journal of sexual medicine 20070701
Pediatric migraine: pharmacologic agents for prophylaxis. The Annals of pharmacotherapy 20070701
5-HT2A: its role in frontally mediated executive function and related psychopathology. CNS spectrums 20070701
[The effectiveness of treatment with trazodone in patients with primary insomnia without and with prior history of hypnotics use]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070701
Association of low bone mineral density with selective serotonin reuptake inhibitor use by older men. Archives of internal medicine 20070625
Dexamethasone-induced posterior reversible encephalopathy syndrome. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070610
The management of insomnia in the older adult. Medicine and health, Rhode Island 20070601
Eugenosedin-A amelioration of lipopolysaccharide-induced up-regulation of p38 MAPK, inducible nitric oxide synthase and cyclooxygenase-2. The Journal of pharmacy and pharmacology 20070601
A gero-informatics tool to enhance the care of hospitalized older adults with cognitive impairment. Clinical interventions in aging 20070601
Rasagiline - a novel MAO B inhibitor in Parkinson's disease therapy. Therapeutics and clinical risk management 20070601
A translational, caffeine-induced model of onset insomnia in rats and healthy volunteers. Psychopharmacology 20070501
Possible intranasal quetiapine misuse. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070401
The influence of galantamine on reaction time, attention processes, and performance variability in elderly Alzheimer patients. Journal of clinical psychopharmacology 20070401
A placebo-controlled trial of bupropion SR in the treatment of chronic posttraumatic stress disorder. Journal of clinical psychopharmacology 20070401
Recommendations for the management of migraine in paediatric patients. Expert opinion on pharmacotherapy 20070401
Noncardiac chest pain: current treatment. Gastroenterology & hepatology 20070401
The investigation of electrospun polymer nanofibers as a solid-phase extraction sorbent for the determination of trazodone in human plasma. Analytica chimica acta 20070321
Suicide by multidrug ingestion: hypothesis on the role played by the self-administration of activated charcoal. The American journal of forensic medicine and pathology 20070301
Frontotemporal dementia: recommendations for therapeutic studies, designs, and approaches. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20070301
Influence of antidepressants on hemostasis. Dialogues in clinical neuroscience 20070301
The role of cohort studies in drug development: clinical evidence of antiviral activity of serotonin reuptake inhibitors and HMG-CoA reductase inhibitors in the central nervous system. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20070301
Challenges of fragmented care in long-term management of pelvic pain. The Journal of family practice 20070301
False-positive xerostomia following radioactive iodine treatment: case report. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20070201
Does trazodone have a role in palliating symptoms? Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070201
Beta-endorphins as possible markers for therapeutic drug monitoring. Bosnian journal of basic medical sciences 20070201
What is the future of peer review? Why is there fraud in science? Is plagiarism out of control? Why do scientists do bad things? Is it all a case of: 'all that is necessary for the triumph of evil is that good men do nothing'? Vascular health and risk management 20070201
Japanese experience with milnacipran, the first serotonin and norepinephrine reuptake inhibitor in Japan. Neuropsychiatric disease and treatment 20070201
Therapeutic options for sleep-maintenance and sleep-onset insomnia. Pharmacotherapy 20070101
Use of a computer-based reminder to improve sedative-hypnotic prescribing in older hospitalized patients. Journal of the American Geriatrics Society 20070101
Pharmacological treatment of insomnia for individuals with brain injury. The Journal of head trauma rehabilitation 20070101
Dissecting the determinants of depressive disorders outcome: an in depth analysis of two clinical cases. Annals of general psychiatry 20070101
An internet survey of 2,596 people with fibromyalgia. BMC musculoskeletal disorders 20070101
Trazodone and ejaculatory inhibition. Journal of sex & marital therapy 20070101
Newer antipsychotics and the rabbit syndrome. Clinical practice and epidemiology in mental health : CP & EMH 20070101
Frontotemporal dementias: a review. Annals of general psychiatry 20070101
Update on the safety considerations in the management of insomnia with hypnotics: incorporating modified-release formulations into primary care. Primary care companion to the Journal of clinical psychiatry 20070101
[Applications and safety of modern antidepressants in patients with liver diseases]. Wiadomosci lekarskie (Warsaw, Poland : 1960) 20070101
Tinnitus treatment with Trazodone. Brazilian journal of otorhinolaryngology 20070101
Greater incidence of depression with hypnotic use than with placebo. BMC psychiatry 20070101
Prolonged hypotension due to deliberate trazodone overdose in the presence of fluoxetine. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20070101
[Clinical relevance of antidepressant-induced activation syndrome: from a perspective of bipolar spectrum disorder]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20070101
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors]. Voprosy onkologii 20070101
Escitalopram induced mania. Indian journal of psychiatry 20070101
Spectrophotometric determination of trazodone, amineptine and amitriptyline hydrochlorides through ion-pair formation with molybdenum and thiocyanate. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061201
Modeling anxiety-like states: pharmacological characterization of the chick separation stress paradigm. Behavioural pharmacology 20061101
Counseling patients about sexual issues. Pharmacotherapy 20061101
Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine. Journal of pharmacological sciences 20061101
Successful treatment of alcohol withdrawal with trazodone. Pharmacopsychiatry 20061101
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020
Solid-phase extraction and analysis of 20 antidepressant drugs in human plasma by LC/MS with SSI method. Forensic science international 20061016
Liquid chromatography/mass spectrometry for the quantitation of muraglitazar in monkey plasma. Biomedical chromatography : BMC 20061001
Spectrophotometric determination of trazodone, amineptine and amitriptyline hydrochlorides through ion-pair formation using methyl orange and bromocresol green reagents. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060901
Methylphenidate for alpha-interferon induced depression. Journal of psychopharmacology (Oxford, England) 20060901
Treatment of sleep dysfunction and psychiatric disorders. Current treatment options in neurology 20060901
Compulsions in depression: stalking by text message. The American journal of psychiatry 20060901
Antidepressants and violence: problems at the interface of medicine and law. PLoS medicine 20060901
A comparative, randomized, double-blind study of trazodone prolonged-release and sertraline in the treatment of major depressive disorder. Current medical research and opinion 20060901
Prophylaxis of migraine. Neuropsychiatric disease and treatment 20060901
Concomitant medications may not improve outcome of antipsychotic monotherapy for stabilized patients with nonacute schizophrenia. The Journal of clinical psychiatry 20060801
The four-plates test: anxiolytic or analgesic paradigm? Progress in neuro-psychopharmacology & biological psychiatry 20060701
Do antidepressants cure or create abnormal brain states? PLoS medicine 20060701
Sensitive extractive spectrophotometric methods for the determination of trazodone hydrochloride in pharmaceutical formulations. Chemical & pharmaceutical bulletin 20060701
Patient characteristics and patterns of drug use for sleep complaints in the United States: analysis of National Ambulatory Medical Survey data, 1997-2002. Clinical therapeutics 20060701
Insomnia in the elderly: cause, approach, and treatment. The American journal of medicine 20060601
[Trazodone for the treatment of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease: a retrospective study focused on the aggression and negativism in caregiving situations]. No to shinkei = Brain and nerve 20060601
Management of chronic insomnia in elderly persons. The American journal of geriatric pharmacotherapy 20060601
Depression and sleep: pathophysiology and treatment. Dialogues in clinical neuroscience 20060601
Treatment of Alzheimer's disease across the spectrum of severity. Clinical interventions in aging 20060601
Neuroleptic malignant syndrome induced by atypical neuroleptics and responsive to lorazepam. Neuropsychiatric disease and treatment 20060601
Prophylactic treatment of migraine in children. Part 2. A systematic review of pharmacological trials. Cephalalgia : an international journal of headache 20060501
On call. I am 47 years old and I've always been healthy. My main problem is insomnia. Sleeping pills don't work well, and they make me feel groggy. Finally, my doctor gave me a prescription for Desyrel, and he seems to have hit the bull's-eye. I've been sleeping much better and haven't noticed any side effects. But my pharmacist warned me about abnormal erections. Is it a serious concern? Harvard men's health watch 20060501
[Effects of antidepressants on sleep]. Orvosi hetilap 20060430
Use of antidepressant medications in relation to the incidence of breast cancer. British journal of cancer 20060410
Optimization of dansyl derivatization and chromatographic conditions in the determination of neuroactive amino acids of biological samples. Clinica chimica acta; international journal of clinical chemistry 20060401
Inhibition of hepatobiliary transport as a predictive method for clinical hepatotoxicity of nefazodone. Toxicological sciences : an official journal of the Society of Toxicology 20060401
Delirium in older persons. The New England journal of medicine 20060316
Determination of antidepressants in surface and waste water samples by capillary electrophoresis with electrospray ionization mass spectrometric detection after preconcentration using off-line solid-phase extraction. Electrophoresis 20060301
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The AGNP-TDM Expert Group Consensus Guidelines: focus on therapeutic monitoring of antidepressants. Dialogues in clinical neuroscience 20050901
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Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn-Schmiedeberg's archives of pharmacology 20040801
Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone. Naunyn-Schmiedeberg's archives of pharmacology 20040801
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'A comparison of the effectiveness of two hypnotic agents for the treatment of insomnia'. The international journal of psychiatric nursing research 20040801
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The use of trazodone as a hypnotic: a critical review. The Journal of clinical psychiatry 20040601
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A comparative solid-phase extraction study for the simultaneous determination of fluvoxamine, mianserin, doxepin, citalopram, paroxetine, and etoperidone in whole blood by capillary gas-liquid chromatography with nitrogen-phosphorus detection. Journal of analytical toxicology 20040401
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Prescriptions of antidepressants in primary care in Italy: pattern of use after admission of selective serotonin reuptake inhibitors for reimbursement. European journal of clinical pharmacology 20040101
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The effects of trazodone on sleep in patients treated with stimulant antidepressants. Sleep medicine 20040101
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An automated approach to salt selection for new unique trazodone salts. Pharmaceutical research 20040101
SSRI treatment-associated stroke: causality assessment in two cases. The Annals of pharmacotherapy 20040101
Frontotemporal dementia: a randomised, controlled trial with trazodone. Dementia and geriatric cognitive disorders 20040101
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Treatment of primary insomnia. The Journal of the American Board of Family Practice 20040101
Development of a capillary zone electrophoretic method to determine six antidepressants in their pharmaceutical preparations. Experimental design for evaluating the ruggedness of method. Journal of separation science 20040101
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Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction. Drug safety 20040101
Daytime sleepiness and insomnia as correlates of depression. The Journal of clinical psychiatry 20040101
Therapeutic drug monitoring of non-tricyclic antidepressant drugs. Clinical chemistry and laboratory medicine 20040101
Biological pathophysiology of mood disorders special reference to the neurotransmitter receptors. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20040101
[Assessment of CYP2D6 activity as a form of optimizing antidepressant therapy]. Psychiatria polska 20040101
Treatment of seasonal affective disorders. Dialogues in clinical neuroscience 20031201
Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia. British journal of cancer 20031117
Common problems in patients recovering from chemical dependency. American family physician 20031115
Open pilot study of gabapentin versus trazodone to treat insomnia in alcoholic outpatients. Psychiatry and clinical neurosciences 20031001
Trazodone for erectile dysfunction: a systematic review and meta-analysis. BJU international 20030901
A comparative solid-phase extraction study for the simultaneous determination of fluoxetine, amitriptyline, nortriptyline, trimipramine, maprotiline, clomipramine, and trazodone in whole blood by capillary gas-liquid chromatography with nitrogen-phosphorus detection. Journal of analytical toxicology 20030901
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Double-blind, placebo-controlled study of the efficacy of trazodone in alcohol post-withdrawal syndrome: polysomnographic and clinical evaluations. Journal of clinical psychopharmacology 20030801
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New colorimetric methods for the determination of trazodone HCl, famotidine, and diltiazem HCl in their pharmaceutical dosage forms. Analytical and bioanalytical chemistry 20030701
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Alcohol, nicotine, caffeine, and mental disorders. Dialogues in clinical neuroscience 20030601
Olanzapine in the treatment-resistant, combat-related PTSD--a series of case reports. Acta psychiatrica Scandinavica 20030501
A fatal drug interaction between oxycodone and clonazepam. Journal of forensic sciences 20030501
Switch to mania upon discontinuation of antidepressants in patients with mood disorders: a review of the literature. Canadian journal of psychiatry. Revue canadienne de psychiatrie 20030501
Trazodone hydrochloride attenuates thermal hyperalgesia in a chronic constriction injury rat model. European journal of anaesthesiology 20030501
Short-term exposure to low-dose ritonavir impairs clearance and enhances adverse effects of trazodone. Journal of clinical pharmacology 20030401
Unexplained transient hyperphosphatemia is more common in acute psychiatric disorders than in acute medical-surgical conditions. Psychiatry research 20030325
Electroanalytical characteristics of piribedil and its differential pulse and square wave voltammetric determination in pharmaceuticals and human serum. Journal of pharmaceutical and biomedical analysis 20030310
Assessment of the contributions of CYP3A4 and CYP3A5 in the metabolism of the antipsychotic agent haloperidol to its potentially neurotoxic pyridinium metabolite and effect of antidepressants on the bioactivation pathway. Drug metabolism and disposition: the biological fate of chemicals 20030301
A multicentre prospective controlled study to determine the safety of trazodone and nefazodone use during pregnancy. Canadian journal of psychiatry. Revue canadienne de psychiatrie 20030301
Mianserin and trazodone significantly attenuate the intensity of opioid withdrawal symptoms in mice. Addiction biology 20030301
Behavioral disturbances in dementia. Dialogues in clinical neuroscience 20030301
Association of low dose trazodone treatment with aggravated angle-closure glaucoma. Psychiatry and clinical neurosciences 20030201
Pharmacologic management by clinical pharmacists of behavioral and psychological symptoms of dementia in nursing home residents: results from a pilot study. Pharmacotherapy 20030201
Treatment of sleep disturbance in alcohol recovery: a national survey of addiction medicine physicians. Journal of addictive diseases 20030101
Dissociative symptoms from combined treatment with sertraline and trazodone. The Journal of neuropsychiatry and clinical neurosciences 20030101
Treatment of neuroleptic-induced akathisia with the 5-HT2A antagonist trazodone. Clinical neuropharmacology 20030101
Folate for depressive disorders. The Cochrane database of systematic reviews 20030101
Antidepressants for generalized anxiety disorder. The Cochrane database of systematic reviews 20030101
Drugs for preventing migraine headaches in children. The Cochrane database of systematic reviews 20030101
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Delirium. Clinical medicine (London, England) 20030101
[Interest of the use of pindolol in the treatment of depression: review]. L'Encephale 20030101
Piperazine-derived designer drug 1-(3-chlorophenyl)piperazine (mCPP): GC-MS studies on its metabolism and its toxicological detection in rat urine including analytical differentiation from its precursor drugs trazodone and nefazodone. Journal of analytical toxicology 20030101
Confirmation of the neurophysiologically predicted therapeutic effects of trazodone on its target symptoms depression, anxiety and insomnia by postmarketing clinical studies with a controlled-release formulation in depressed outpatients. Neuropsychobiology 20030101
The treatment of generalised anxiety disorder. A systematic review. Panminerva medica 20021201
Simultaneous quantification of citalopram, clozapine, fluoxetine, norfluoxetine, maprotiline, desmethylmaprotiline and trazodone in human serum by HPLC analysis. International journal of clinical pharmacology and therapeutics 20021201
Sleep-wake mechanisms and drug discovery: sleep EEG as a tool for the development of CNS-acting drugs. Dialogues in clinical neuroscience 20021201
Clitoral priapism: a rare condition presenting as a cause of vulvar pain. Obstetrics and gynecology 20021101
In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone. Xenobiotica; the fate of foreign compounds in biological systems 20021101
Voluntary undertaking rule and duty to warn. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021001
Voltammetric analysis of trazodone HCl in pharmaceuticals and biological fluids. Journal of pharmaceutical and biomedical analysis 20020905
Erectile dysfunction: oral pharmacotherapy options. International journal of clinical pharmacology and therapeutics 20020901
The pharmacologic management of SSRI-induced side effects: a survey of psychiatrists. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20020901
Sleep in posttraumatic stress disorder. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20020901
Psychopharmacology of anxiety disorders. Dialogues in clinical neuroscience 20020901
Alterations in 5-HT(1A) receptors and adenylyl cyclase response by trazodone in regions of rat brain. Life sciences 20020816
Alpha(1)-adrenoceptor antagonists. 4. Pharmacophore-based design, synthesis, and biological evaluation of new imidazo-, benzimidazo-, and indoloarylpiperazine derivatives. Journal of medicinal chemistry 20020815
Effects of antidepressants in rats trained to discriminate centrally administered isoproterenol. The Journal of pharmacology and experimental therapeutics 20020801
Relationship between plasma concentrations of trazodone and its active metabolite, m-chlorophenylpiperazine, and its clinical effect in depressed patients. Therapeutic drug monitoring 20020801
Effects of trazodone and imipramine on the biological rhythm: an analysis of sleep EEG and body core temperature. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20020801
Priapism associated with trazodone in an adolescent with autism. Journal of the American Academy of Child and Adolescent Psychiatry 20020701
[Chronobiological research on antidepressant drugs: the effect of the antidepressant drugs, trazodone and imipramine on the circadian rhythm using electroencephalography in healthy volunteers]. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20020601
Pharmacological aspects of erectile dysfunction. Japanese journal of pharmacology 20020601
An overview of the clinical efficacy of mirtazapine. Human psychopharmacology 20020601
[Latest therapies for treating dementia]. Atencion primaria 20020515
Psychotropic drugs and the ECG: focus on the QTc interval. Expert opinion on pharmacotherapy 20020501
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Paroxetine associated hepatotoxicity: a report of 3 cases and a review of the literature. Pharmacopsychiatry 20020501
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Induction of hyperlocomotion in mice exposed to a novel environment by inhibition of serotonin reuptake. A pharmacological characterization of diverse classes of antidepressant agents. Pharmacology, biochemistry, and behavior 20020401
Serotonin releasing agents. Neurochemical, therapeutic and adverse effects. Pharmacology, biochemistry, and behavior 20020401
Citalopram-induced priapism. Pharmacotherapy 20020401
Detecting drug-drug interactions in medication profiles of psychiatric inpatients: a two-stage approach. Journal of the Formosan Medical Association = Taiwan yi zhi 20020401
Pathophysiology of depression and mechanisms of treatment. Dialogues in clinical neuroscience 20020301
The clinical pharmacology of depressive states. Dialogues in clinical neuroscience 20020301
alpha(1)-Adrenoceptor antagonists. Rational design, synthesis and biological evaluation of new trazodone-like compounds. Bioorganic & medicinal chemistry letters 20020211
Early polyneuropharmacologic intervention in brain injury agitation. American journal of physical medicine & rehabilitation 20020201
Insomnia in depression: differences in objective and subjective sleep and awakening quality to normal controls and acute effects of trazodone. Progress in neuro-psychopharmacology & biological psychiatry 20020201
A hemodialysis patient with trazodone-induced parkinsonism. Nephron 20020201
AAS and AES determination of furaltadone, methadone and trazodone in pharmaceutical formulations. Journal of pharmaceutical and biomedical analysis 20020101
Noncardiac chest pain. Journal of clinical gastroenterology 20020101
An 8-year-old boy with autism, 1 year later. JAMA 20020101
Chronic stress impairs rotarod performance in rats: implications for depressive state. Pharmacology, biochemistry, and behavior 20020101
Effects of psychotropic drugs on seizure threshold. Drug safety 20020101
Masturbatory guilt leading to severe depression and erectile dysfunction. Journal of sex & marital therapy 20020101
No long-term effect of behavioral treatment on psychotropic drug use for agitation in Alzheimer's disease patients. Journal of geriatric psychiatry and neurology 20020101
Potential interactions between herbal medicines and conventional drug therapies used by older adults attending a memory clinic. Drugs & aging 20020101
[Depression in epilepsy: symptom or syndrome?]. La Clinica terapeutica 20020101
Inhibitory presynaptic 5-hydroxytryptamine(2A) receptors regulate evoked glutamate release from rat cerebellar mossy fibers. The Journal of pharmacology and experimental therapeutics 20011201
Venlafaxine- and trazodone-induced serotonin syndrome. The American journal of psychiatry 20011201
Misdiagnosis of myoclonus in antidepressant induced serotonin excess. Veterinary and human toxicology 20011201
Hepatotoxicity after short-term trazodone therapy. The Annals of pharmacotherapy 20011201
Central nervous system agents in the treatment of erectile dysfunction: how do they work? Current urology reports 20011201
An unusual presentation of sertraline and trazodone overdose. The Annals of pharmacotherapy 20011101
Treatment of insomnia in hospitalized patients. The Annals of pharmacotherapy 20011101
Evaluation of the absorption, excretion and metabolism of [14C] etoperidone in man. Xenobiotica; the fate of foreign compounds in biological systems 20011101
[Pharmacotherapeutical approaches to insomnia patients with cardiac diseases and after heart transplantation]. Zeitschrift fur Kardiologie 20011001
Antidepressant drug prescribing in Italy, 2000: analysis of a general practice database. European journal of clinical pharmacology 20011001
Does behavioral improvement with haloperidol or trazodone treatment depend on psychosis or mood symptoms in patients with dementia? Journal of the American Geriatrics Society 20011001
A display of hypomania in a depressed male in response to fluvoxamine. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20011001
Spectrophotometric, spectrofluorimetric and LC determination of trazodone hydrochloride. Journal of pharmaceutical and biomedical analysis 20010901
Antagonism of nicotinic acetylcholine receptors by inhibitors of monoamine uptake. Molecular psychiatry 20010901
Cognitive toxicity of drugs used in the elderly. Dialogues in clinical neuroscience 20010901
Low frequency rTMS as an add-on antidepressive strategy: heterogeneous impact on 99mTc-HMPAO and 18 F-FDG uptake as measured simultaneously with the double isotope SPECT technique. Pilot study. Nuclear medicine communications 20010801
Myoclonus secondary to the concurrent use of trazodone and fluoxetine. Veterinary and human toxicology 20010801
Use of drugs by Old Age Psychiatrists in the treatment of psychotic and behavioural symptoms in patients with dementia. Aging & mental health 20010801
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry 20010719
P-glycoprotein interactions of nefazodone and trazodone in cell culture. Journal of clinical pharmacology 20010701
Survey on the usefulness of trazodone in patients with PTSD with insomnia or nightmares. Pharmacopsychiatry 20010701
Effects of genetic polymorphism of CYP1A2 inducibility on the steady-state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazine in depressed Japanese patients. Pharmacology & toxicology 20010501
Pharmacology of erectile function and dysfunction. The Urologic clinics of North America 20010501
Acute trazodone and quipazine treatment attenuates apomorphine-induced aggressive behaviour in male rats without major impact on emotional behaviour or monoamine content post mortem. Pharmacological research 20010401
Synthesis and pharmacological evaluation of aryl/heteroaryl piperazinyl alkyl benzotriazoles as ligands for some serotonin and dopamine receptor subtypes. Farmaco (Societa chimica italiana : 1989) 20010401
[Incidence of priapism at the Marqués de Valdecilla University Hospital in Santander]. Archivos espanoles de urologia 20010401
The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism. Pharmacology, biochemistry, and behavior 20010401
Screening for detection of new antidepressants, neuroleptics, hypnotics, and their metabolites in urine by GC-MS developed using rat liver microsomes. Therapeutic drug monitoring 20010201
Recommendations for the management of behavioral and psychological symptoms of dementia. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20010201
Electroconvulsive therapy and cardiovascular complications in patients taking trazodone for insomnia. The Journal of clinical psychiatry 20010201
Serotonin syndrome. A common but often unrecognized psychiatric condition. Geriatrics 20010101
Weight outcomes among antidepressant users in nursing facilities. Journal of the American Geriatrics Society 20010101
Antidepressants as analgesics: a review of randomized controlled trials. Journal of psychiatry & neuroscience : JPN 20010101
[Depressive disorders in neurologic rehabilitation: therapy with paroxetine]. Psychiatrische Praxis 20010101
Mania resulting from continuous positive airways pressure in a depressed man with sleep apnea syndrome. Neuropsychobiology 20010101
Possible mild serotonin syndrome related to co-prescription of tandospirone and trazodone. General hospital psychiatry 20010101
False-positive amphetamine screen following a trazodone overdose. Journal of toxicology. Clinical toxicology 20010101
Inhibition of K(+)-evoked release of rat striatal 5-hydroxytryptamine by an atypical antidepressant: trazodone. Neuropsychobiology 20010101
Treatment of the agitation of late-life psychosis and Alzheimer's disease. European psychiatry : the journal of the Association of European Psychiatrists 20010101
Smoking in patients receiving psychotropic medications: a pharmacokinetic perspective. CNS drugs 20010101
Insomnia related to dysthymia: polysomnographic and psychometric comparison with normal controls and acute therapeutic trials with trazodone. Neuropsychobiology 20010101
Fatal overdose with trazodone: case report and literature review. Acta clinica Belgica 20010101
The neuropharmacology of upper airway motor control in the awake and asleep states: implications for obstructive sleep apnoea. Respiratory research 20010101
Antidepressants versus placebo for people with bulimia nervosa. The Cochrane database of systematic reviews 20010101
Interactions between herbal medicines and prescribed drugs: a systematic review. Drugs 20010101
Successful treatment with trazodone for repetitive behavior in schizophrenia. Nordic journal of psychiatry 20010101
National Patterns of Medication Treatment for Depression, 1987 to 2001. Primary care companion to the Journal of clinical psychiatry 20010101
Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. Circulation 20001205
Lethal combination of tramadol and multiple drugs affecting serotonin. The American journal of forensic medicine and pathology 20001201
Fluoxetine-induced sexual dysfunction reversed by trazodone. Canadian journal of psychiatry. Revue canadienne de psychiatrie 20001101
Coma in a patient with Alzheimer's disease taking low dose trazodone and gingko biloba. Journal of neurology, neurosurgery, and psychiatry 20000501
Antidepressant exacerbation of spasticity. Archives of physical medicine and rehabilitation 19990301
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