Loxapine P-glycoprotein interactions in vitro.

Drug metabolism letters 20120301

New pyridobenzoxazepine derivatives derived from 5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine (JL13): chemical synthesis and pharmacological evaluation.

Journal of medicinal chemistry 20120223

Rapid acute treatment of agitation in patients with bipolar I disorder: a multicenter, randomized, placebo-controlled clinical trial with inhaled loxapine.

Bipolar disorders 20120201

[RÉALITÉ LT, a pharmacoepidemiological study of semiology and therapeutic strategy of patients with schizophrenia treated by antipsychotic loxapine in routine clinical practice].

L'Encephale 20120201

The oxidative degradation of dibenzoazepine derivatives by cerium(IV) complexes in acidic sulfate media.

Dalton transactions (Cambridge, England : 2003) 20120128

Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC-MS/MS.

Journal of pharmaceutical and biomedical analysis 20120125

Modeling psychiatric disorders through reprogramming.

Disease models & mechanisms 20120101

Now take a deep breath: inhaled loxapine for the treatment of acute agitation.

Journal of psychosocial nursing and mental health services 20120101

The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease.

Parkinson's disease 20120101

Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs: population based cohort study.

BMJ (Clinical research ed.) 20120101

Heart rate-corrected QT interval helps predict mortality after intentional organophosphate poisoning.

PloS one 20120101

Palladium-catalyzed reaction of aryl iodides with ortho-bromoanilines and norbornene/norbornadiene: unexpected formation of dibenzoazepine derivatives.

Angewandte Chemie (International ed. in English) 20111216

Neuroleptic malignant syndrome-like reaction precipitated by antipsychotics in a patient with gamma-butyrolactone withdrawal.

Journal of addiction medicine 20111201

Swallowing difficulties: a prognostic signpost.

Canadian family physician Medecin de famille canadien 20111201

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

PLoS computational biology 20111201

Efficacy and safety of loxapine for inhalation in the treatment of agitation in patients with schizophrenia: a randomized, double-blind, placebo-controlled trial.

The Journal of clinical psychiatry 20111001

In vitro identification of the human cytochrome p450 enzymes involved in the oxidative metabolism of loxapine.

Biopharmaceutics & drug disposition 20111001

The pharmacoepidemiology of antipsychotics for adults with schizophrenia in Canada, 2005 to 2009.

Canadian journal of psychiatry. Revue canadienne de psychiatrie 20111001

'Extended' antipsychotic dosing in the maintenance treatment of schizophrenia: a double-blind, placebo-controlled trial.

The Journal of clinical psychiatry 20110801

Inhaled loxapine reduces acute agitation in people with schizophrenia compared with placebo.

Evidence-based mental health 20110801

New uses for old drugs: pharmacophore-based screening for the discovery of P-glycoprotein inhibitors.

Chemical biology & drug design 20110701

Combination loxapine and aripiprazole for refractory hallucinations in schizophrenia.

The Annals of pharmacotherapy 20110701

Quality of life after electroconvulsive therapy in persons with treatment resistant schizophrenia.

The Indian journal of medical research 20110601

The dopaminergic system in peripheral blood lymphocytes: from physiology to pharmacology and potential applications to neuropsychiatric disorders.

Current neuropharmacology 20110601

Modelling schizophrenia using human induced pluripotent stem cells.

Nature 20110512

The benefits of an active control arm.

The British journal of psychiatry : the journal of mental science 20110401

Aerosolised antipsychotic assuages agitation: inhaled loxapine for agitation associated with schizophrenia or bipolar disorder.

International journal of clinical practice 20110301

Interaction of clozapine and its nitrenium ion with rat D2 dopamine receptors: in vitro binding and computational study.

Journal of computer-aided molecular design 20110201

In vitro aerosol characterization of Staccato(®) Loxapine.

International journal of pharmaceutics 20110117

Rapid acute treatment of agitation in individuals with schizophrenia: multicentre, randomised, placebo-controlled study of inhaled loxapine.

The British journal of psychiatry : the journal of mental science 20110101

Meeting on big mutations addresses big questions in human genetics.

Genome medicine 20110101

Pharmacotherapy for treatment-resistant schizophrenia.

Neuropsychiatric disease and treatment 20110101

Malignant catatonia due to anti-NMDA-receptor encephalitis in a 17-year-old girl: case report.

Child and adolescent psychiatry and mental health 20110101

Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways.

PloS one 20110101

Homicide and associated steroid acute psychosis: a case report.

Case reports in medicine 20110101

Validation of HPLC-MS/MS methods for analysis of loxapine, amoxapine, 7-OH-loxapine, 8-OH-loxapine and loxapine N-oxide in human plasma.

Bioanalysis 20101201

Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.

Healthcare informatics research 20101201

In vitro aerosol deposition in the oropharyngeal region for Staccato loxapine.

Journal of aerosol medicine and pulmonary drug delivery 20100801

4-Nitro-2-phenoxy-aniline.

Acta crystallographica. Section E, Structure reports online 20100601

Pharmacokinetics of loxapine following inhalation of a thermally generated aerosol in healthy volunteers.

Journal of clinical pharmacology 20100201

[Catatonia in a 14 year-old girl: treatment with clorazepam and carbamazepine, a 10-year follow-up].

L'Encephale 20100201

Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28.

Bioorganic & medicinal chemistry 20100115

Simultaneous HPLC determination of 14 tricyclic antidepressants and metabolites in human plasma.

Journal of separation science 20100101

Identifying unexpected therapeutic targets via chemical-protein interactome.

PloS one 20100101

Beneficial effects of loxapine on agitation and breathing patterns during weaning from mechanical ventilation.

Critical care (London, England) 20100101

Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data.

BMC bioinformatics 20100101

Pharmacological interventions for borderline personality disorder.

The Cochrane database of systematic reviews 20100101

A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting.

Annals of general psychiatry 20100101

Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients.

Neuropsychiatric disease and treatment 20100101

An overview of Indian research in schizophrenia.

Indian journal of psychiatry 20100101

The association between class of antipsychotic and rates of hospitalization: results of a retrospective analysis of data from the 2005 Medicare current beneficiary survey.

Clinical therapeutics 20091201

Psychotic woman with painful abdominal distension. Life-threatening psychotropic drug-induced gastrointestinal hypomotility.

Annals of emergency medicine 20091101

Use and safety of antipsychotic drugs during pregnancy.

Journal of psychiatric practice 20090501

Finding my faith.

Indian journal of psychiatry 20090101

Bacitracin-sensitive aminopeptidase(s) degradation of methionine(5)-enkephalin by human brain putamen and hippocampus preparations: inhibition by phenothiazine drugs.

American journal of therapeutics 20090101

Rapid liquid chromatography/tandem mass spectrometer (LCMS) method for clozapine and its metabolite N-desmethyl clozapine (norclozapine) in human serum.

Journal of clinical laboratory analysis 20090101

Current perspectives in the treatment of resistant schizophrenia.

Indian journal of psychiatry 20090101

Spectroscopic and electrochemical analysis of psychotropic drugs.

Indian journal of pharmaceutical sciences 20090101

Safety and efficacy of antipsychotic drugs for the behavioral and psychological symptoms of dementia.

Indian journal of psychiatry 20090101

Neuroanatomical, neurochemical, and neurodevelopmental basis of obsessive-compulsive symptoms in schizophrenia.

Indian journal of psychological medicine 20090101

Hospitalization risk associated with typical and atypical antipsychotic use in community-dwelling elderly patients.

The American journal of geriatric pharmacotherapy 20081001

HPLC analysis of the antidepressant trazodone and its main metabolite m-CPP in human plasma.

Journal of pharmaceutical and biomedical analysis 20080805

Analysis of the recent antipsychotic aripiprazole in human plasma by capillary electrophoresis and high-performance liquid chromatography with diode array detection.

Analytica chimica acta 20080407

Efficacy and tolerability of second-generation antipsychotics in children and adolescents with schizophrenia.

Schizophrenia bulletin 20080101

Incorporating clinical guidelines through clinician decision-making.

Implementation science : IS 20080101

The effect of antipsychotic medication on sexual function and serum prolactin levels in community-treated schizophrenic patients: results from the Schizophrenia Trial of Aripiprazole (STAR) study (NCT00237913).

BMC psychiatry 20080101

Modifications of antiepileptic drugs for improved tolerability and efficacy.

Perspectives in medicinal chemistry 20080101

Loxapine for schizophrenia.

The Cochrane database of systematic reviews 20071017

Determination of clozapine and its metabolite, norclozapine in various biological matrices using high-performance liquid chromatography.

Drug development and industrial pharmacy 20071001

Pharmacological causes of hyperprolactinemia.

Therapeutics and clinical risk management 20071001

HPLC analysis of the novel antidepressant duloxetine in human plasma after an original solid-phase extraction procedure.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070901

Simultaneous analysis of classical neuroleptics, atypical antipsychotics and their metabolites in human plasma.

Analytical and bioanalytical chemistry 20070501

Risk of extrapyramidal syndrome in schizophrenic patients treated with antipsychotics: a population-based study.

Clinical pharmacology and therapeutics 20070401

Simultaneous determination of methadone, buprenorphine and norbuprenorphine in biological fluids for therapeutic drug monitoring purposes.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301

Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly patients.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070227

Simultaneous determination of the antipsychotic drugs levomepromazine and clozapine and their main metabolites in human plasma by a HPLC-UV method with solid-phase extraction.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201

Correlations between weight changes and lipid profile changes in schizophrenic patients after antipsychotics therapy.

Chang Gung medical journal 20070101

Effect of loxapine on electrical brain activity, intracranial pressure, and middle cerebral artery flow velocity in traumatic brain-injured patients.

Neurocritical care 20070101

Clozapine: Current perspective.

Indian journal of psychiatry 20070101

Lack of enhanced effect of antipsychotics combined with fluvoxamine on acetylcholine release in rat prefrontal cortex.

Journal of pharmacological sciences 20061201

Synthesis, characterization, antimicrobial and single crystal X-ray crystallographic studies of some new sulfonyl, 4-chloro phenoxy benzene and dibenzoazepine substituted benzamides.

European journal of medicinal chemistry 20061101

Systematic review of antipsychotics for the treatment of hospital-associated delirium in medically or surgically ill patients.

The Annals of pharmacotherapy 20061101

Loxapine treatment in an autistic child with aggressive behavior: therapeutic challenges.

Journal of child and adolescent psychopharmacology 20061001

Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: a review.

The Journal of clinical psychiatry 20060901

Characterization of the histamine H4 receptor binding site. Part 1. Synthesis and pharmacological evaluation of dibenzodiazepine derivatives.

Journal of medicinal chemistry 20060727

[Efficacy and adverse reactions of antipsychotics for neuropsychiatric symptoms in dementia: a systematic review].

Nederlands tijdschrift voor geneeskunde 20060715

Adjunctive topiramate in ultradian cycling bipolar disorder: case report with 3-year follow-up.

European psychiatry : the journal of the Association of European Psychiatrists 20060601

Increasing psychosis in a patient switched from clozaril to generic clozapine.

The American journal of psychiatry 20060401

Time to discontinuation of atypical versus typical antipsychotics in the naturalistic treatment of schizophrenia.

BMC psychiatry 20060101

[Clinical and socio-demographic profile of patients with schizophrenia according to the antipsychotic treatment prescribed].

L'Encephale 20060101

[Therapeutics approach of adult patients with acute and chronic psychotic states: REALITE survey].

L'Encephale 20060101

NMS after clozapine initiation.

Journal of the American Academy of Child and Adolescent Psychiatry 20051101

Contrasting loxapine to its isomer isoloxapine--the critical role of in vivo D2 blockade in determining atypicality.

Schizophrenia research 20050915

Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.

Psychopharmacology 20050501

Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.

Journal of medicinal chemistry 20050324

Minimally effective doses of conventional antipsychotic medications used to treat aggression, self-injurious and destructive behaviors in mentally retarded adults.

Journal of clinical psychopharmacology 20050201

Atypical and typical antipsychotic drug interactions with the dopamine D2 receptor.

European journal of medicinal chemistry 20050201

Treatment of acute mania--from clinical trials to recommendations for clinical practice.

Human psychopharmacology 20050101

Chlorpromazine and loxapine reduce interleukin-1beta and interleukin-2 release by rat mixed glial and microglial cell cultures.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050101

Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors.

European journal of pharmacology 20040714

Transient hyperproinsulinemia during treatment with clozapine and amisulpride.

The Journal of clinical psychiatry 20040601

Treatment-refractory schizophrenia.

Dialogues in clinical neuroscience 20040301

Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.

Journal of medicinal chemistry 20040101

An assessment of quality of sleep and the use of drugs with sedating properties in hospitalized adult patients.

Health and quality of life outcomes 20040101

[Agranulocytosis induced by loxapine in an elderly patient: a case study].

Therapie 20040101

Simultaneous determination of four antipsychotic drugs in plasma by high-performance liquid chromatography. Application to management of acute intoxications.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031005

Effects of some antidepressant drugs on tryptaminergic responses of the rat jejunum.

Pharmacology 20031001

Neuroleptic malignant syndrome: case report and discussion.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030902

Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).

Journal of medicinal chemistry 20030703

Differential effects of atypical and typical antipsychotic drugs on N-methyl-D-aspartate- and electrically evoked responses in the pyramidal cells of the rat medial prefrontal cortex.

Synapse (New York, N.Y.) 20030501

A comparison of the effects of loxapine with ziprasidone and thioridazine on the release of dopamine and acetylcholine in the prefrontal cortex and nucleus accumbens.

Psychopharmacology 20030501

Induction of hyperglycemia in mice with atypical antipsychotic drugs that inhibit glucose uptake.

Pharmacology, biochemistry, and behavior 20030501

H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030301

Human genetic variations in the 5HT2A receptor: a single nucleotide polymorphism identified with altered response to clozapine.

Pharmacogenetics 20030201

In vitro human plasma leucine(5)-enkephalin degradation is inhibited by a select number of drugs with the phenothiazine molecule in their chemical structure.

Pharmacology 20030101

Effect of loxapine on peripheral dopamine-like and serotonin receptors in patients with schizophrenia.

Journal of psychiatry & neuroscience : JPN 20030101

JL 13, an atypical antipsychotic: a preclinical review.

CNS drug reviews 20030101

Loxapine versus olanzapine in the treatment of delirium following traumatic brain injury.

NeuroRehabilitation 20030101

[Survey of management methods for patients in a state of agitation at admission and emergency departments in France].

L'Encephale 20030101

Interspecies variability and drug interactions of loxapine metabolism in liver microsomes.

European journal of drug metabolism and pharmacokinetics 20030101

Discriminative stimulus properties in rats of the novel antipsychotic quetiapine.

Experimental and clinical psychopharmacology 20021101

Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH.

Acta crystallographica. Section D, Biological crystallography 20020601

Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

The Journal of biological chemistry 20020419

Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation.

Archives of general psychiatry 20020401

[Self-poisoning with Datura stramonium. 3 case reports].

Presse medicale (Paris, France : 1983) 20020119

Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study.

BMC psychiatry 20020101

TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243].

BMC psychiatry 20020101

Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine.

Brain research 20011227

A new class of antiarrhythmic-defibrillatory agents.

Bioorganic & medicinal chemistry letters 20011119

Inverse agonist actions of typical and atypical antipsychotic drugs at the human 5-hydroxytryptamine(2C) receptor.

The Journal of pharmacology and experimental therapeutics 20011001

Treatment of the special patient with schizophrenia.

Dialogues in clinical neuroscience 20010601

Re: Neuroleptic malignant syndrome associated with quetiapine.

Canadian journal of psychiatry. Revue canadienne de psychiatrie 20010501

Loxapine side-effects: 3 case reports of hyperleukocytosis.

Therapie 20010101

Clinically significant drug interactions with agents specific for migraine attacks.

CNS drugs 20010101

[Body weight changes and psychotropic drug treatment: neuroleptics].

L'Encephale 20010101

Thioridazine for dementia.

The Cochrane database of systematic reviews 20010101

[Psychiatric manifestations of lupus erythematosus systemic and Sjogren's syndrome].

L'Encephale 20010101

Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.

The Journal of pharmacology and experimental therapeutics 20001001

Olanzapine-induced tardive dystonia.

The American journal of psychiatry 19991001

Does loxapine have 'atypical' properties? Clinical evidence.

The Journal of clinical psychiatry 19990101

The role of alpha2-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat.

British journal of pharmacology 19980801

Clozapine inhibits catalepsy induced by olanzapine and loxapine, but prolongs catalepsy induced by SCH 23390 in rats.

Naunyn-Schmiedeberg's archives of pharmacology 19970301

Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 19970201

Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.

Journal of neurochemistry 19960101

Emergence of symptoms of Tourette's syndrome during fluvoxamine treatment of obsessive-compulsive disorder.

The British journal of psychiatry : the journal of mental science 19940601

Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.

The Journal of pharmacology and experimental therapeutics 19940301

Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.

The Journal of biological chemistry 19930825

Biologically active conformers of phenothiazines and thioxanthenes. Further evidence for a ligand model of dopamine D2 receptor antagonists.

Journal of medicinal chemistry 19930723

Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.

Molecular pharmacology 19930301

Simultaneous quantitation of loxapine, amoxapine and their 7- and 8-hydroxy metabolites in plasma by high-performance liquid chromatography.

Journal of chromatography 19910308

Loxapine-lorazepam-induced hypotension and stupor.

Journal of clinical psychopharmacology 19890601

Neurotoxicity resulting from a combination of lithium and loxapine.

The Journal of clinical psychiatry 19890501

Neurotoxicity induced by combined lithium-thioridazine treatment.

Biological psychiatry 19860701

Rapid tranquilization: a comparison of thiothixene with loxapine.

The Journal of clinical psychiatry 19860601

Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes.

Proceedings of the National Academy of Sciences of the United States of America 19840901

Drug interactions on spontaneous locomotor activity in rats. Neuroleptics and amphetamine-induced hyperactivity.

Neuropharmacology 19840801

Loxapine versus chlorpromazine in paranoid schizophrenia: a double-blind study.

The Journal of clinical psychiatry 19840401

Neuroleptic-induced catatonia: case report.

The Journal of clinical psychiatry 19830801

Neuroleptic malignant syndrome associated with loxapine.

The Journal of clinical psychiatry 19830101

Efficacy of antipsychotic medications in behaviorally disturbed dementia patients.

The American journal of psychiatry 19820901

Sexual dysfunction in women using major tranquilizers.

Psychosomatics 19820901

Loxapine succinate as initial treatment of hostile and aggressive schizophrenic criminal offenders.

Journal of clinical pharmacology 19820101

Seizures induced by acute loxapine overdose.

The American journal of psychiatry 19810801

Evaluations of loxapine succinate in the ambulatory treatment of acute schizophrenic episodes.

International pharmacopsychiatry 19800101

[Loxapine succinate: a new neuroleptic].

L'Encephale 19790101

A two year trial of loxapine succinate in chronic psychotic patients.

Diseases of the nervous system 19760501

Treatment of acute psychotic patients with loxapine parenterally.

Current therapeutic research, clinical and experimental 19760201

[The assessment of neuroleptogenic extrapyramidal syndroms in psychopharmacological research (author's transl)].

Pharmakopsychiatrie, Neuro-Psychopharmakologie 19750101